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Results for mixl1+mxtx1+sebox

Z-value: 0.81

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Transcription factors associated with mixl1+mxtx1+sebox

Gene Symbol Gene ID Gene Info
sebox
ENSDARG00000042526 SEBOX homeobox
mixl1
ENSDARG00000069252 Mix paired-like homeobox
mxtx1
ENSDARG00000069382 mix-type homeobox gene 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mxtx1dr10_dc_chr13_-_21529695_21529754-0.302.7e-01Click!
mixl1dr10_dc_chr20_-_43826581_438265930.273.1e-01Click!
seboxdr10_dc_chr5_+_66693263_66693284-0.126.7e-01Click!

Activity profile of mixl1+mxtx1+sebox motif

Sorted Z-values of mixl1+mxtx1+sebox motif

Network of associatons between targets according to the STRING database.

First level regulatory network of mixl1+mxtx1+sebox

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr21_+_25740782 4.97 ENSDART00000021620
cldnd
claudin d
chr18_-_40718244 3.29 ENSDART00000077577
si:ch211-132b12.8
si:ch211-132b12.8
chr10_-_34971985 3.06 ENSDART00000141201
ccna1
cyclin A1
chr8_+_45326435 2.99 ENSDART00000134161
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr12_-_14104939 2.91 ENSDART00000152742
buc2l
bucky ball 2-like
chr17_+_16038358 2.73 ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr24_+_12689711 2.61 ENSDART00000114762
nanog
nanog homeobox
chr11_-_6442588 2.58 ENSDART00000137879
zgc:162969
zgc:162969
chr10_-_25246786 2.58 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr1_-_18118467 2.53 ENSDART00000142026
si:dkey-167i21.2
si:dkey-167i21.2
chr5_+_37303599 2.44 ENSDART00000097754
ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr10_-_21404605 2.44 ENSDART00000125167
avd
avidin
chr17_-_45021393 2.42

chr14_+_34150130 2.31 ENSDART00000132193
ENSDART00000141058
wnt8a
BX927327.1
wingless-type MMTV integration site family, member 8a
ENSDARG00000105311
chr20_-_14218080 2.26 ENSDART00000104032
si:ch211-223m11.2
si:ch211-223m11.2
chr16_-_29452509 2.16 ENSDART00000148787
s100a1
S100 calcium binding protein A1
chr22_-_17627900 2.16 ENSDART00000138483
si:ch73-243b8.4
si:ch73-243b8.4
chr19_+_15536640 2.07 ENSDART00000098970
lin28a
lin-28 homolog A (C. elegans)
chr17_+_16038103 2.04 ENSDART00000155005
si:ch73-204p21.2
si:ch73-204p21.2
chr1_-_54570813 2.03 ENSDART00000098615
nanos3
nanos homolog 3
chr20_-_23527234 1.97 ENSDART00000004625
zar1
zygote arrest 1
chr24_+_8702288 1.95 ENSDART00000114810
sycp2l
synaptonemal complex protein 2-like
chr10_-_34971926 1.90 ENSDART00000141201
ccna1
cyclin A1
chr2_+_6341404 1.78 ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr21_-_32027717 1.77 ENSDART00000131651
ENSDARG00000073961
ENSDARG00000073961
chr24_+_19270877 1.66

chr16_+_47283253 1.65 ENSDART00000062507
ica1
islet cell autoantigen 1
chr10_+_6925373 1.65 ENSDART00000128866
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr3_+_28729443 1.56 ENSDART00000077235
alg1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr20_+_14218237 1.50 ENSDART00000044937
kcns3b
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3b
chr22_+_4035577 1.49 ENSDART00000170620
ctxn1
cortexin 1
chr24_+_12689887 1.45 ENSDART00000114762
nanog
nanog homeobox
chr14_-_8634381 1.36 ENSDART00000129030
zgc:153681
zgc:153681
KN149710v1_+_38638 1.32

chr1_+_18118735 1.30 ENSDART00000078610
slc25a51a
solute carrier family 25, member 51a
chr16_+_47283374 1.26 ENSDART00000062507
ica1
islet cell autoantigen 1
chr18_-_43890836 1.23 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr10_-_25448712 1.22 ENSDART00000140023
grik1a
glutamate receptor, ionotropic, kainate 1a
chr18_+_20571460 1.20 ENSDART00000151990
wee2
WEE1 homolog 2 (S. pombe)
chr16_-_29451902 1.18

chr1_+_21244200 1.16 ENSDART00000087729
kdm4c
lysine (K)-specific demethylase 4C
chr1_+_35253862 1.16 ENSDART00000139636
zgc:152968
zgc:152968
chr10_-_32550351 1.14 ENSDART00000129395
uvrag
UV radiation resistance associated gene
chr6_+_40925259 1.12 ENSDART00000002728
ENSDART00000145153
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr19_-_5186692 1.12 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr11_+_34909167 1.09 ENSDART00000110839
mon1a
MON1 secretory trafficking family member A
chr8_+_41003546 1.08 ENSDART00000129344
gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr11_-_34909095 1.08 ENSDART00000017393
traip
TRAF-interacting protein
chr11_+_34909244 1.07 ENSDART00000110839
mon1a
MON1 secretory trafficking family member A
chr8_+_11387135 1.04

chr15_-_16241412 1.03 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr8_-_44247277 1.02

chr16_+_42567707 1.02 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr14_+_23420053 1.01 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr18_+_20571400 0.99 ENSDART00000151990
wee2
WEE1 homolog 2 (S. pombe)
chr7_+_28341426 0.99 ENSDART00000019991
slc7a6os
solute carrier family 7, member 6 opposite strand
chr21_+_34053739 0.96 ENSDART00000147519
mtmr1b
myotubularin related protein 1b
chr17_-_25630635 0.96 ENSDART00000149060
ppp1cb
protein phosphatase 1, catalytic subunit, beta isozyme
chr2_-_27892824 0.92

chr5_+_6391432 0.83 ENSDART00000170564
ENSDART00000086666
stpg2
sperm-tail PG-rich repeat containing 2
chr20_-_14218236 0.81 ENSDART00000168434
si:ch211-223m11.2
si:ch211-223m11.2
chr24_+_16924542 0.80 ENSDART00000014787
pip4k2aa
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a
chr20_+_54404987 0.79 ENSDART00000099338
actr10
ARP10 actin related protein 10 homolog
chr1_+_21244242 0.77 ENSDART00000087729
kdm4c
lysine (K)-specific demethylase 4C
chr8_-_1833095 0.75 ENSDART00000114476
ENSDART00000091235
ENSDART00000140077
pi4kab
phosphatidylinositol 4-kinase, catalytic, alpha b
chr21_+_34053590 0.74 ENSDART00000147519
ENSDART00000158115
ENSDART00000029599
ENSDART00000145123
mtmr1b
myotubularin related protein 1b
chr18_+_19467527 0.74 ENSDART00000079695
zwilch
zwilch kinetochore protein
chr8_-_19236074 0.74 ENSDART00000137994
zgc:77486
zgc:77486
chr20_-_16271738 0.72 ENSDART00000012476
coa7
cytochrome c oxidase assembly factor 7
chr21_-_36710989 0.71 ENSDART00000086060
mrpl22
mitochondrial ribosomal protein L22
chr11_-_6442490 0.69 ENSDART00000137879
zgc:162969
zgc:162969
chr6_+_48188549 0.69

chr23_-_25208472 0.67 ENSDART00000103989
ENSDART00000160278
idh3g
isocitrate dehydrogenase 3 (NAD+) gamma
chr21_-_25765319 0.66 ENSDART00000101219
mettl27
methyltransferase like 27
chr1_+_8010026 0.66 ENSDART00000152142
zgc:77849
zgc:77849
chr20_-_37910887 0.66 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr2_+_6341345 0.65 ENSDART00000058256
zp3b
zona pellucida glycoprotein 3b
chr5_-_18459312 0.64 ENSDART00000145210
ankle2
ankyrin repeat and LEM domain containing 2
chr14_+_23419864 0.63 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr6_+_50382153 0.63 ENSDART00000055504
cyc1
cytochrome c-1
chr7_+_26378093 0.63 ENSDART00000173823
ENSDART00000101053
tp53i11a
tumor protein p53 inducible protein 11a
chr3_-_39554099 0.62 ENSDART00000145303
b9d1
B9 protein domain 1
chr8_-_21039978 0.61 ENSDART00000137606
ENSDART00000146532
zgc:112962
zgc:112962
chr11_-_12024136 0.61 ENSDART00000111919
sp2
sp2 transcription factor
chr18_+_20571785 0.60 ENSDART00000040074
wee2
WEE1 homolog 2 (S. pombe)
chr14_-_33605295 0.59 ENSDART00000168546
zdhhc24
zinc finger, DHHC-type containing 24
chr7_+_8492338 0.58

chr13_-_35346618 0.58 ENSDART00000057052
slx4ip
SLX4 interacting protein
chr23_-_31986679 0.56 ENSDART00000085054
mtfr2
mitochondrial fission regulator 2
chr5_+_37303707 0.54 ENSDART00000097754
ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr8_+_45326523 0.54 ENSDART00000145011
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr12_+_3632548 0.54

chr4_-_5822882 0.54 ENSDART00000008898
foxm1
forkhead box M1
chr11_+_34909393 0.53 ENSDART00000110839
mon1a
MON1 secretory trafficking family member A
chr3_-_26112995 0.53 ENSDART00000103741
ppp4ca
protein phosphatase 4, catalytic subunit a
chr8_+_50964745 0.52 ENSDART00000013870
ENSDARG00000007359
ENSDARG00000007359
chr3_-_26113336 0.51 ENSDART00000103741
ppp4ca
protein phosphatase 4, catalytic subunit a
chr3_+_26113651 0.51 ENSDART00000103734
atad5a
ATPase family, AAA domain containing 5a
chr14_+_34150232 0.51 ENSDART00000148044
wnt8a
wingless-type MMTV integration site family, member 8a
KN150200v1_+_7782 0.49

chr6_-_32001100 0.49 ENSDART00000132280
ror1
receptor tyrosine kinase-like orphan receptor 1
chr8_-_5834829 0.48 ENSDART00000179217
ENSDARG00000106522
ENSDARG00000106522
chr24_+_16402587 0.48 ENSDART00000164319
sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr24_-_24999348 0.48 ENSDART00000152104
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr8_+_36467811 0.47 ENSDART00000098701
slc7a4
solute carrier family 7, member 4
chr15_-_16241500 0.46 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr24_-_14447825 0.45

chr25_-_28630138 0.45

chr11_+_26366532 0.45 ENSDART00000159505
dynlrb1
dynein, light chain, roadblock-type 1
chr6_+_49489473 0.43 ENSDART00000177749
FO704848.1
ENSDARG00000107438
chr16_+_42567668 0.43 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr8_-_25015215 0.42 ENSDART00000170511
nfyal
nuclear transcription factor Y, alpha, like
chr16_-_42105636 0.41 ENSDART00000102798
zp3d.2
zona pellucida glycoprotein 3d tandem duplicate 2
chr3_+_26113393 0.41 ENSDART00000103733
atad5a
ATPase family, AAA domain containing 5a
chr14_+_8634323 0.41 ENSDART00000159920
rps6kal
ribosomal protein S6 kinase a, like
chr8_+_26377369 0.39 ENSDART00000087151
amt
aminomethyltransferase
chr6_+_48188609 0.37

chr24_-_14447655 0.36

chr6_-_51771558 0.35 ENSDART00000073847
blcap
bladder cancer associated protein
chr8_+_41003629 0.35 ENSDART00000129344
gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr17_-_41000670 0.34 ENSDART00000124715
si:dkey-16j16.4
si:dkey-16j16.4
chr24_+_12689972 0.34 ENSDART00000114762
nanog
nanog homeobox
chr17_+_8642373 0.34 ENSDART00000105326
tonsl
tonsoku-like, DNA repair protein
chr23_-_31986571 0.33 ENSDART00000135526
mtfr2
mitochondrial fission regulator 2
chr24_-_14447519 0.32

chr22_-_20141216 0.28 ENSDART00000128023
btbd2a
BTB (POZ) domain containing 2a
chr11_+_33555374 0.26 ENSDART00000109418
spoplb
speckle-type POZ protein-like b
chr16_-_42105733 0.26 ENSDART00000102798
zp3d.2
zona pellucida glycoprotein 3d tandem duplicate 2
chr25_-_24440292 0.25 ENSDART00000156805
CR854832.1
ENSDARG00000096817
chr17_-_41809859 0.24 ENSDART00000156031
ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr23_+_22763739 0.22

chr3_-_13311188 0.21 ENSDART00000080807
fbxw9
F-box and WD repeat domain containing 9
chr11_+_34259003 0.21

chr24_-_24578984 0.21 ENSDART00000012399
armc1
armadillo repeat containing 1
chr10_+_6925975 0.21

chr24_+_12690117 0.19 ENSDART00000114762
nanog
nanog homeobox
chr22_+_20141311 0.18

chr16_-_26798351 0.18

chr15_-_45304762 0.15 ENSDART00000177018
CABZ01068243.1
ENSDARG00000106883
chr17_+_8642428 0.15 ENSDART00000105326
tonsl
tonsoku-like, DNA repair protein
chr5_-_66441778 0.14 ENSDART00000168245
rps6ka4
ribosomal protein S6 kinase, polypeptide 4
chr24_+_16924429 0.12 ENSDART00000014787
pip4k2aa
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a
chr2_+_50873843 0.10

chr23_-_31986482 0.08 ENSDART00000135526
mtfr2
mitochondrial fission regulator 2
chr13_+_25590508 0.07 ENSDART00000046050
pcbd1
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
chr1_+_35253821 0.07 ENSDART00000179634
zgc:152968
zgc:152968
chr8_-_16370646 0.06 ENSDART00000115419
faf1
Fas (TNFRSF6) associated factor 1
chr20_-_21031592 0.03 ENSDART00000152726
btbd6b
BTB (POZ) domain containing 6b
chr1_-_28335293 0.03 ENSDART00000075546
hsf2bp
heat shock transcription factor 2 binding protein
chr16_+_6809981 0.02 ENSDART00000149720
znf236
zinc finger protein 236
chr15_+_1569864 0.02 ENSDART00000056765
smc4
structural maintenance of chromosomes 4
chr15_-_16241341 0.01 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr11_-_36188531 0.01 ENSDART00000128889
zbtb40
zinc finger and BTB domain containing 40
chr14_+_23419894 0.00 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.6 GO:0043622 cortical microtubule organization(GO:0043622)
0.7 2.6 GO:0039015 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.6 2.8 GO:0060631 regulation of meiosis I(GO:0060631)
0.5 1.4 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.4 1.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 2.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 2.9 GO:0050796 regulation of insulin secretion(GO:0050796)
0.2 5.0 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.2 0.7 GO:0030730 regulation of sequestering of triglyceride(GO:0010889) positive regulation of sequestering of triglyceride(GO:0010890) sequestering of triglyceride(GO:0030730)
0.2 3.1 GO:0035803 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2 1.7 GO:0061458 gonad development(GO:0008406) reproductive structure development(GO:0048608) reproductive system development(GO:0061458)
0.2 0.8 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.7 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.1 1.0 GO:0048532 anatomical structure arrangement(GO:0048532)
0.1 0.6 GO:0035264 multicellular organism growth(GO:0035264)
0.1 0.4 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.7 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 5.0 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 0.6 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 2.7 GO:0006623 protein targeting to vacuole(GO:0006623)
0.1 0.6 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.6 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.5 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.1 2.0 GO:0048599 oocyte development(GO:0048599)
0.0 1.2 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 1.0 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 1.0 GO:0000266 mitochondrial fission(GO:0000266)
0.0 1.6 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 1.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.4 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 2.2 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 0.5 GO:0031297 replication fork processing(GO:0031297)
0.0 1.5 GO:0051260 protein homooligomerization(GO:0051260)
0.0 2.2 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.5 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0 0.6 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.6 GO:0048634 regulation of muscle organ development(GO:0048634)
0.0 0.6 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.7 GO:0042255 ribosome assembly(GO:0042255)
0.0 1.8 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.3 GO:0031397 negative regulation of protein ubiquitination(GO:0031397) negative regulation of protein modification by small protein conjugation or removal(GO:1903321)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.7 2.6 GO:0097189 apoptotic body(GO:0097189)
0.3 2.9 GO:0030667 secretory granule membrane(GO:0030667)
0.2 3.7 GO:0043186 P granule(GO:0043186)
0.1 4.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 1.5 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 0.5 GO:0035101 FACT complex(GO:0035101)
0.1 0.6 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.8 GO:0005869 dynactin complex(GO:0005869)
0.1 4.5 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 0.7 GO:0005811 lipid particle(GO:0005811)
0.0 3.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.7 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.7 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 1.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:0009374 biotin binding(GO:0009374)
0.4 1.1 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.3 1.4 GO:1903231 mRNA binding involved in posttranscriptional gene silencing(GO:1903231)
0.3 3.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.3 2.4 GO:0035804 structural constituent of egg coat(GO:0035804)
0.2 1.4 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.2 1.6 GO:0050699 WW domain binding(GO:0050699)
0.2 1.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 1.8 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 0.7 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.2 2.6 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.8 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 1.2 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 3.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.7 GO:0032190 acrosin binding(GO:0032190)
0.1 5.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 2.6 GO:0005109 frizzled binding(GO:0005109)
0.1 0.6 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 2.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 1.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 2.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 1.5 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 9.6 GO:0042802 identical protein binding(GO:0042802)
0.0 0.6 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 2.1 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 2.9 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.4 GO:0008483 transaminase activity(GO:0008483)
0.0 1.2 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.6 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.5 GO:0017147 Wnt-protein binding(GO:0017147)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 4.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.5 ST GA13 PATHWAY G alpha 13 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.0 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import