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Results for mnx2a

Z-value: 0.46

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Transcription factors associated with mnx2a

Gene Symbol Gene ID Gene Info
mnx2a
ENSDARG00000042106 motor neuron and pancreas homeobox 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mnx2adr10_dc_chr9_+_7745593_77456010.621.1e-02Click!

Activity profile of mnx2a motif

Sorted Z-values of mnx2a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of mnx2a

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_+_56157608 1.49 ENSDART00000149665
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr18_-_3056732 1.17 ENSDART00000162657
rps3
ribosomal protein S3
chr16_+_23516127 1.10 ENSDART00000004679
icn
ictacalcin
chr17_+_23278879 0.93 ENSDART00000153652
zgc:165461
zgc:165461
chr20_-_22576513 0.92 ENSDART00000103510
pdgfra
platelet-derived growth factor receptor, alpha polypeptide
chr22_-_26333957 0.89 ENSDART00000130493
capn2b
calpain 2, (m/II) large subunit b
chr3_-_29768364 0.72 ENSDART00000020311
rpl27
ribosomal protein L27
chr3_+_25992836 0.63 ENSDART00000010477
hsp70.3
heat shock cognate 70-kd protein, tandem duplicate 3
chr12_+_24221087 0.63 ENSDART00000088178
nrxn1a
neurexin 1a
chr7_-_25623974 0.61 ENSDART00000173602
cd99l2
CD99 molecule-like 2
chr19_-_43037791 0.61 ENSDART00000004392
fkbp9
FK506 binding protein 9
chr9_-_31467299 0.60 ENSDART00000022204
zic5
zic family member 5 (odd-paired homolog, Drosophila)
chr14_-_17257773 0.58 ENSDART00000082667
fgfrl1a
fibroblast growth factor receptor-like 1a
chr23_+_25428372 0.57 ENSDART00000147440
fmnl3
formin-like 3
chr15_-_4537178 0.57 ENSDART00000155619
ENSDART00000128602
tfdp2
transcription factor Dp-2
chr3_-_27516974 0.56 ENSDART00000151675
si:ch211-157c3.4
si:ch211-157c3.4
chr24_-_6048914 0.54 ENSDART00000146830
ENSDART00000021981
apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr2_-_34010299 0.53 ENSDART00000140910
ptch2
patched 2
chr25_-_19388415 0.51 ENSDART00000156016
zgc:193812
zgc:193812
chr2_+_49358871 0.50 ENSDART00000179089
sema6ba
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba
chr21_+_28441951 0.49 ENSDART00000077887
slc22a6l
solute carrier family 22 (organic anion transporter), member 6, like
chr8_-_34077387 0.49 ENSDART00000159208
ENSDART00000040126
ENSDART00000048994
ENSDART00000098822
pbx3b
pre-B-cell leukemia homeobox 3b
chr14_+_20045365 0.48 ENSDART00000167637
aff2
AF4/FMR2 family, member 2
chr15_-_23441268 0.48 ENSDART00000078570
c1qtnf5
C1q and TNF related 5
chr9_-_20562293 0.45 ENSDART00000113418
igsf3
immunoglobulin superfamily, member 3
chr16_-_55320569 0.45 ENSDART00000156368
ENSDARG00000069583
ENSDARG00000069583
chr6_+_23787804 0.45 ENSDART00000163188
znf648
zinc finger protein 648
chr16_+_23172295 0.44 ENSDART00000167518
ENSDART00000161087
efna3b
ephrin-A3b
chr14_+_160149 0.44 ENSDART00000158405
ENSDART00000158072
gpc2
glypican 2
chr5_-_41672394 0.43 ENSDART00000164363
si:ch211-207c6.2
si:ch211-207c6.2
chr14_+_36156947 0.42

chr19_-_6384776 0.42

chr14_+_21816442 0.41 ENSDART00000109759
tmx2a
thioredoxin-related transmembrane protein 2a
chr20_-_9107294 0.41 ENSDART00000140792
OMA1
OMA1 zinc metallopeptidase
chr3_-_6078015 0.40 ENSDART00000165715
BX284638.1
ENSDARG00000098850
chr23_-_31585883 0.39 ENSDART00000157511
eya4
EYA transcriptional coactivator and phosphatase 4
chr24_+_21395671 0.39 ENSDART00000091529
wasf3b
WAS protein family, member 3b
chr1_-_25600988 0.38 ENSDART00000160381
cxxc4
CXXC finger 4
chr14_-_2682064 0.38 ENSDART00000161677
si:dkey-201i24.6
si:dkey-201i24.6
chr22_+_2921305 0.38 ENSDART00000143258
cep19
centrosomal protein 19
chr20_+_21002097 0.37 ENSDART00000035827
brf1b
BRF1, RNA polymerase III transcription initiation factor b
chr8_+_39964695 0.37 ENSDART00000073782
ggt5a
gamma-glutamyltransferase 5a
chr22_+_16509286 0.37 ENSDART00000083063
tal1
T-cell acute lymphocytic leukemia 1
chr22_+_12746080 0.36 ENSDART00000044683
ftcd
formimidoyltransferase cyclodeaminase
chr20_-_48677794 0.36 ENSDART00000124040
ENSDART00000148437
insm1a
insulinoma-associated 1a
chr17_-_52735250 0.36

chr2_-_40170303 0.36 ENSDART00000165602
epha4a
eph receptor A4a
chr22_-_20141589 0.36 ENSDART00000085913
btbd2a
BTB (POZ) domain containing 2a
chr4_+_16896821 0.36 ENSDART00000017726
etnk1
ethanolamine kinase 1
chr6_+_24299180 0.34 ENSDART00000167482
tgfbr3
transforming growth factor, beta receptor III
chr16_+_51319421 0.34

chr16_+_21436660 0.34 ENSDART00000145886
osbpl3b
oxysterol binding protein-like 3b
chr18_-_14709371 0.33 ENSDART00000111995
si:dkey-238o13.4
si:dkey-238o13.4
chr17_+_30352361 0.33 ENSDART00000076611
greb1
growth regulation by estrogen in breast cancer 1
chr16_-_21238288 0.33 ENSDART00000139737
cbx3b
chromobox homolog 3b
chr1_-_40208544 0.33 ENSDART00000027463
hmx4
H6 family homeobox 4
chr6_+_13833991 0.32

chr4_+_3970874 0.32 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr1_-_40208469 0.32 ENSDART00000027463
hmx4
H6 family homeobox 4
chr24_-_14447773 0.31

chr25_+_30701751 0.31

chr14_+_4169846 0.30 ENSDART00000038301
gnpda2
glucosamine-6-phosphate deaminase 2
chr11_-_6051096 0.30 ENSDART00000147761
vsg1
vessel-specific 1
chr8_-_11512545 0.30 ENSDART00000133932
si:ch211-248e11.2
si:ch211-248e11.2
chr19_-_43038013 0.30 ENSDART00000004392
fkbp9
FK506 binding protein 9
chr12_+_5046825 0.29 ENSDART00000164178
prrt2
proline-rich transmembrane protein 2
chr19_+_5562107 0.29 ENSDART00000082080
jupb
junction plakoglobin b
chr6_+_45917081 0.28 ENSDART00000149450
ENSDART00000149642
h6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr20_+_28958586 0.28 ENSDART00000142678
slc10a1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr11_-_6442836 0.28 ENSDART00000004483
zgc:162969
zgc:162969
chr19_+_22478256 0.27 ENSDART00000100181
sall3b
spalt-like transcription factor 3b
chr8_-_19166630 0.26

chr18_-_43890514 0.26 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr21_+_26684617 0.25 ENSDART00000053797
slc3a2b
solute carrier family 3 (amino acid transporter heavy chain), member 2b
chr22_-_20141216 0.25 ENSDART00000128023
btbd2a
BTB (POZ) domain containing 2a
chr23_+_36016450 0.25 ENSDART00000103035
hoxc6a
homeobox C6a
chr9_-_30243398 0.25 ENSDART00000139863
ENSDART00000140040
dcbld2
discoidin, CUB and LCCL domain containing 2
chr3_+_27667194 0.25 ENSDART00000075100
carhsp1
calcium regulated heat stable protein 1
chr7_+_25052687 0.25 ENSDART00000110347
cyp26b1
cytochrome P450, family 26, subfamily b, polypeptide 1
chr13_+_25590508 0.24 ENSDART00000046050
pcbd1
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
chr10_-_24401876 0.24 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr3_-_27517052 0.24 ENSDART00000151625
si:ch211-157c3.4
si:ch211-157c3.4
KN149726v1_+_1094 0.24

chr13_-_44492897 0.23

chr8_+_2428689 0.23 ENSDART00000081325
dynll1
dynein, light chain, LC8-type 1
chr1_+_11290598 0.22 ENSDART00000103399
tspan5b
tetraspanin 5b
chr25_+_15842875 0.22 ENSDART00000126641
ppfibp2b
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr17_-_52735615 0.22

chr8_+_43334181 0.22 ENSDART00000038566
fam101a
family with sequence similarity 101, member A
chr7_+_19300351 0.21 ENSDART00000169060
si:ch211-212k18.5
si:ch211-212k18.5
chr22_-_2921219 0.21 ENSDART00000092991
pigx
phosphatidylinositol glycan anchor biosynthesis, class X
chr9_+_34832049 0.21 ENSDART00000100735
ENSDART00000133996
shox
short stature homeobox
chr1_-_50215233 0.20 ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr6_-_57542101 0.19 ENSDART00000156967
itcha
itchy E3 ubiquitin protein ligase a
chr17_-_37447917 0.19 ENSDART00000075975
crip1
cysteine-rich protein 1
chr18_-_16600954 0.19 ENSDART00000143744
mgat4c
mgat4 family, member C
chr10_+_37193690 0.19 ENSDART00000114909
cuedc1a
CUE domain containing 1a
chr7_-_25624212 0.18 ENSDART00000173505
cd99l2
CD99 molecule-like 2
chr1_-_31379323 0.18 ENSDART00000101958
pnpla4
patatin-like phospholipase domain containing 4
chr23_+_17220363 0.18 ENSDART00000143420
BX927275.2
ENSDARG00000095017
chr14_-_15845445 0.17 ENSDART00000162431
ptcd3
pentatricopeptide repeat domain 3
chr6_-_11544518 0.17 ENSDART00000151195
march7
membrane-associated ring finger (C3HC4) 7
chr14_-_32543646 0.17 ENSDART00000105726
slc25a5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr24_-_6641762 0.17 ENSDART00000114700
unm_sa821
un-named sa821
chr17_-_37447869 0.17 ENSDART00000148160
crip1
cysteine-rich protein 1
chr8_+_25015325 0.17 ENSDART00000140617
ngrn
neugrin, neurite outgrowth associated
chr20_-_37587804 0.17 ENSDART00000166106
si:ch211-202p1.5
si:ch211-202p1.5
chr11_-_19612693 0.16 ENSDART00000037894
namptb
nicotinamide phosphoribosyltransferase b
chr6_+_28215039 0.16 ENSDART00000104394
smx5
smx5
chr15_-_16241341 0.16 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr23_-_40873523 0.16 ENSDART00000127420
ENSDARG00000088040
ENSDARG00000088040
chr13_+_47175 0.15 ENSDART00000102505
foxg1d
forkhead box G1d
chr19_+_42899678 0.15 ENSDART00000076915
si:dkey-166k12.1
si:dkey-166k12.1
chr3_+_15586954 0.15 ENSDART00000080075
phb
prohibitin
chr5_-_33156615 0.15 ENSDART00000159058
dab2ipb
DAB2 interacting protein b
chr17_-_31594647 0.15 ENSDART00000135468
si:dkey-170l10.1
si:dkey-170l10.1
chr5_-_27958815 0.14 ENSDART00000177313
si:ch73-195i19.3
si:ch73-195i19.3
chr11_-_25181234 0.14 ENSDART00000013714
gata1a
GATA binding protein 1a
chr20_-_16553010 0.14

chr5_+_36431824 0.14 ENSDART00000045036
nfkbib
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr13_+_32609784 0.13 ENSDART00000160138
sobpa
sine oculis binding protein homolog (Drosophila) a
chr4_-_19992951 0.13 ENSDART00000169248
drd4-rs
dopamine receptor D4 related sequence
chr9_+_4708975 0.13 ENSDART00000081326
prpf40a
PRP40 pre-mRNA processing factor 40 homolog A
chr8_+_23334921 0.13 ENSDART00000085361
ENSDART00000046460
ENSDART00000145062
dnmt3ba
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a
chr8_-_23591082 0.13 ENSDART00000025024
slc38a5b
solute carrier family 38, member 5b
chr8_-_46903869 0.13 ENSDART00000161462
acot7
acyl-CoA thioesterase 7
chr4_+_14658179 0.13 ENSDART00000168152
abcc9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr17_+_25425967 0.12 ENSDART00000030691
clic4
chloride intracellular channel 4
chr13_-_40027211 0.12

chr2_+_50873893 0.12

chr23_-_36319185 0.11 ENSDART00000139328
znf740b
zinc finger protein 740b
chr2_-_26160882 0.11 ENSDART00000133163
CR392026.2
ENSDARG00000094803
chr6_+_33896684 0.11 ENSDART00000165710
gpbp1l1
GC-rich promoter binding protein 1-like 1
chr7_-_25624128 0.11 ENSDART00000173505
cd99l2
CD99 molecule-like 2
chr5_+_65754237 0.11 ENSDART00000170757
kntc1
kinetochore associated 1
chr3_-_38642067 0.10 ENSDART00000155518
znf281a
zinc finger protein 281a
chr11_+_24582928 0.09 ENSDART00000135443
kdm5ba
lysine (K)-specific demethylase 5Ba
chr6_+_3120600 0.09 ENSDART00000151359
kdm4aa
lysine (K)-specific demethylase 4A, genome duplicate a
chr9_-_39190534 0.09

chr6_-_3837266 0.08 ENSDART00000059212
unc50
unc-50 homolog (C. elegans)
chr8_+_39964882 0.08 ENSDART00000134452
ggt5a
gamma-glutamyltransferase 5a
chr10_+_37193735 0.08 ENSDART00000114909
cuedc1a
CUE domain containing 1a
chr14_+_4169371 0.08 ENSDART00000136665
gnpda2
glucosamine-6-phosphate deaminase 2
chr2_-_6545431 0.07 ENSDART00000161934
si:dkey-119f1.1
si:dkey-119f1.1
chr20_-_15029379 0.07 ENSDART00000152641
dnm3a
dynamin 3a
chr13_+_32609849 0.07 ENSDART00000160138
sobpa
sine oculis binding protein homolog (Drosophila) a
chr16_-_16212890 0.07 ENSDART00000131227
ankib1b
ankyrin repeat and IBR domain containing 1b
chr25_-_27120954 0.07 ENSDART00000157319
hyal4
hyaluronoglucosaminidase 4
chr10_+_3461461 0.06

chr19_+_7019317 0.06 ENSDART00000139122
flot1a
flotillin 1a
chr1_+_9634016 0.06 ENSDART00000029774
tmem55bb
transmembrane protein 55Bb
chr8_+_25015374 0.06 ENSDART00000140617
ngrn
neugrin, neurite outgrowth associated
chr1_-_8439215 0.06 ENSDART00000081337
ndufab1a
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1a
chr25_-_20160885 0.06 ENSDART00000160700
dnm1l
dynamin 1-like
chr20_+_31173383 0.05 ENSDART00000136255
otofa
otoferlin a
chr8_-_8408046 0.05 ENSDART00000132700
cdk16
cyclin-dependent kinase 16
chr11_-_18081944 0.05 ENSDART00000113468
CABZ01112215.1
ENSDARG00000079534
chr19_-_19806070 0.05 ENSDART00000165206
smarcc1b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1b
chr9_-_14302522 0.04 ENSDART00000135458
abcb6b
ATP-binding cassette, sub-family B (MDR/TAP), member 6b
chr21_-_11561793 0.04 ENSDART00000171708
ENSDART00000081614
cast
calpastatin
chr3_+_27655753 0.04 ENSDART00000086994
nat15
N-acetyltransferase 15 (GCN5-related, putative)
chr2_-_25306278 0.04 ENSDART00000132050
hltf
helicase-like transcription factor
chr24_+_16402613 0.03 ENSDART00000164319
sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr21_-_44707326 0.03 ENSDART00000013814
ammecr1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 homolog (human)
chr2_+_50873843 0.03

chr12_-_33871785 0.03 ENSDART00000105545
arl3
ADP-ribosylation factor-like 3
chr11_+_35790782 0.03 ENSDART00000125221
CR933559.1
ENSDARG00000087939
chr13_+_36496475 0.03 ENSDART00000133198
si:ch211-67f24.7
si:ch211-67f24.7
chr10_-_8094671 0.02 ENSDART00000099033
zgc:158494
zgc:158494
chr23_+_28882409 0.02 ENSDART00000078171
pex14
peroxisomal biogenesis factor 14
chr3_+_32700750 0.02 ENSDART00000139410
cd2bp2
CD2 (cytoplasmic tail) binding protein 2
chr3_-_16569378 0.02 ENSDART00000055859
pold1
polymerase (DNA directed), delta 1, catalytic subunit
chr25_-_3345176 0.02 ENSDART00000029067
hbp1
HMG-box transcription factor 1
chr3_-_13311188 0.02 ENSDART00000080807
fbxw9
F-box and WD repeat domain containing 9
chr10_+_29964164 0.02 ENSDART00000118838
SNORD14
Small nucleolar RNA SNORD14
chr7_+_24787720 0.01

chr16_-_42105733 0.01 ENSDART00000102798
zp3d.2
zona pellucida glycoprotein 3d tandem duplicate 2
chr10_-_28142344 0.01 ENSDART00000023545
ints2
integrator complex subunit 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.1 0.4 GO:0052803 imidazole-containing compound metabolic process(GO:0052803) imidazole-containing compound catabolic process(GO:0052805)
0.1 0.4 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 0.5 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 0.5 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.1 0.9 GO:0003315 heart rudiment formation(GO:0003315)
0.1 0.4 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.2 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 0.6 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 1.2 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.1 0.4 GO:1901099 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.4 GO:0006041 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.1 0.4 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 0.6 GO:0021592 fourth ventricle development(GO:0021592)
0.1 0.6 GO:0042026 protein refolding(GO:0042026)
0.1 0.2 GO:0014829 phasic smooth muscle contraction(GO:0014821) vascular smooth muscle contraction(GO:0014829) endocrine process(GO:0050886)
0.1 0.2 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.1 1.5 GO:0071698 olfactory placode development(GO:0071698)
0.1 0.4 GO:0070571 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.0 0.6 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.0 0.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0031280 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclic nucleotide metabolic process(GO:0030800) negative regulation of cyclic nucleotide biosynthetic process(GO:0030803) negative regulation of nucleotide biosynthetic process(GO:0030809) negative regulation of cAMP metabolic process(GO:0030815) negative regulation of cAMP biosynthetic process(GO:0030818) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350) negative regulation of purine nucleotide biosynthetic process(GO:1900372)
0.0 0.2 GO:0015859 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.0 0.2 GO:0046098 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine metabolic process(GO:0046098) guanine biosynthetic process(GO:0046099) hypoxanthine metabolic process(GO:0046100)
0.0 0.2 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.1 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.4 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.0 0.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.3 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.2 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.2 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.4 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.4 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.6 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.3 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.3 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.1 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.1 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.1 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.1 0.4 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.5 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 1.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 0.5 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.1 0.4 GO:0016841 folic acid binding(GO:0005542) ammonia-lyase activity(GO:0016841)
0.1 0.5 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.1 0.3 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.4 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.1 0.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.4 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.2 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 1.9 GO:0019838 growth factor binding(GO:0019838)
0.0 0.1 GO:0099528 G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.1 GO:0051192 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0 0.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.4 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 1.9 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.7 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.3 REACTOME BILE ACID AND BILE SALT METABOLISM Genes involved in Bile acid and bile salt metabolism
0.0 0.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.1 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 1.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.7 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)