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Results for msx2a

Z-value: 0.33

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Transcription factors associated with msx2a

Gene Symbol Gene ID Gene Info
msx2a
ENSDARG00000104651 muscle segment homeobox 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
msx2adr10_dc_chr14_-_23784679_23784711-0.758.1e-04Click!

Activity profile of msx2a motif

Sorted Z-values of msx2a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of msx2a

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr19_-_868378 1.14

chr13_-_18564182 0.71 ENSDART00000176809
sfxn3
sideroflexin 3
chr19_+_31997954 0.59 ENSDART00000164108
gmnn
geminin, DNA replication inhibitor
chr13_+_38100228 0.56 ENSDART00000144093
si:dkeyp-4c7.3
si:dkeyp-4c7.3
chr3_-_15346590 0.47 ENSDART00000124063
sgf29
SAGA complex associated factor 29
chr17_+_23710004 0.46 ENSDART00000034913
zgc:91976
zgc:91976
chr4_-_6407602 0.45 ENSDART00000134376
CR356233.2
ENSDARG00000093020
chr11_+_17849608 0.44 ENSDART00000020283
rpusd4
RNA pseudouridylate synthase domain containing 4
chr7_-_51497945 0.43 ENSDART00000054591
bmp15
bone morphogenetic protein 15
chr17_+_23709781 0.41 ENSDART00000034913
zgc:91976
zgc:91976
chr5_-_18458903 0.40 ENSDART00000145210
ankle2
ankyrin repeat and LEM domain containing 2
chr21_+_5027444 0.40 ENSDART00000139288
si:dkey-121h17.7
si:dkey-121h17.7
chr21_-_2292663 0.40 ENSDART00000164015
zgc:66483
zgc:66483
chr17_+_23709676 0.39 ENSDART00000179026
zgc:91976
zgc:91976
chr6_+_21887963 0.39 ENSDART00000157796
cbx8b
chromobox homolog 8b
chr25_+_32716795 0.39 ENSDART00000131098
ENSDARG00000087402
ENSDARG00000087402
chr3_-_15346427 0.37 ENSDART00000144369
sgf29
SAGA complex associated factor 29
chr14_+_34673281 0.37 ENSDART00000164974
ebf1a
early B-cell factor 1a
chr6_+_21887935 0.35 ENSDART00000157796
cbx8b
chromobox homolog 8b
chr20_+_36957917 0.33 ENSDART00000153091
BX248390.1
ENSDARG00000096735
chr12_+_32316774 0.33 ENSDART00000153144
CT573006.1
ENSDARG00000096761
chr3_-_33811737 0.32 ENSDART00000026090
ENSDART00000047660
ENSDART00000111878
gtf2f1
general transcription factor IIF, polypeptide 1
chr7_-_20322448 0.32 ENSDART00000170850
CR318653.1
ENSDARG00000104557
chr16_-_13723352 0.31 ENSDART00000139102
dbpb
D site albumin promoter binding protein b
chr9_-_40129231 0.31 ENSDART00000177531
CABZ01092969.1
ENSDARG00000108990
chr15_-_23786063 0.30 ENSDART00000109318
zc3h4
zinc finger CCCH-type containing 4
chr21_+_5027623 0.30 ENSDART00000139288
si:dkey-121h17.7
si:dkey-121h17.7
chr3_-_28371648 0.30 ENSDART00000150912
CR792426.1
ENSDARG00000096347
chr22_+_2735606 0.30 ENSDART00000133652
si:dkey-20i20.11
si:dkey-20i20.11
chr25_+_18997440 0.30 ENSDART00000155569
si:dkeyp-19h3.8
si:dkeyp-19h3.8
chr12_-_25126122 0.29 ENSDART00000152931
kcng3
potassium voltage-gated channel, subfamily G, member 3
chr21_+_5027668 0.29 ENSDART00000139288
si:dkey-121h17.7
si:dkey-121h17.7
chr7_+_24257251 0.29 ENSDART00000136473
ENSDARG00000079281
ENSDARG00000079281
chr5_-_19619115 0.29 ENSDART00000026516
pxmp2
peroxisomal membrane protein 2
chr3_-_26675055 0.28 ENSDART00000143710
pigq
phosphatidylinositol glycan anchor biosynthesis, class Q
chr3_+_27582277 0.28 ENSDART00000019004
arhgdig
Rho GDP dissociation inhibitor (GDI) gamma
chr19_-_5186692 0.27 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr5_-_19619201 0.26 ENSDART00000026516
pxmp2
peroxisomal membrane protein 2
chr2_+_1260407 0.26

chr23_+_16848278 0.26 ENSDART00000104791
zgc:153722
zgc:153722
chr4_-_14193396 0.26 ENSDART00000101812
ENSDART00000143804
pus7l
pseudouridylate synthase 7-like
chr4_-_75683584 0.26 ENSDART00000075770
zgc:162948
zgc:162948
chr14_+_29601073 0.25 ENSDART00000143763
fam149a
family with sequence similarity 149 member A
chr7_+_39392939 0.25 ENSDART00000146171
zgc:158564
zgc:158564
chr19_-_27093002 0.25

chr5_-_67839187 0.24

chr5_+_27793171 0.24

chr21_-_13654658 0.23 ENSDART00000111666
npdc1a
neural proliferation, differentiation and control, 1a
chr5_+_71100066 0.23 ENSDART00000115182
nup214
nucleoporin 214
chr16_-_13723295 0.22 ENSDART00000139102
dbpb
D site albumin promoter binding protein b
chr15_-_6969345 0.21 ENSDART00000169529
mrps22
mitochondrial ribosomal protein S22
chr5_+_21673232 0.21 ENSDART00000131223
fdx1b
ferredoxin 1b
chr3_-_15346710 0.20 ENSDART00000007726
sgf29
SAGA complex associated factor 29
chr3_+_32278978 0.19 ENSDART00000061426
rras
related RAS viral (r-ras) oncogene homolog
chr7_-_20322390 0.19 ENSDART00000170850
CR318653.1
ENSDARG00000104557
chr22_+_37696341 0.19 ENSDART00000007346
psmd1
proteasome 26S subunit, non-ATPase 1
chr21_-_39616469 0.19 ENSDART00000026766
aldocb
aldolase C, fructose-bisphosphate, b
chr13_-_40592360 0.19

chr24_-_32668102 0.19 ENSDART00000066590
rdh12l
retinol dehydrogenase 12, like
chr5_-_39077051 0.19

chr14_+_17092009 0.19 ENSDART00000129838
rnf212
ring finger protein 212
chr3_-_58094618 0.19 ENSDART00000093031
snu13a
SNU13 homolog, small nuclear ribonucleoprotein a (U4/U6.U5)
chr16_+_1843899 0.19

chr10_+_35209240 0.19 ENSDART00000126105
nsun5
NOP2/Sun domain family, member 5
chr25_-_36678422 0.18 ENSDART00000087247
glg1a
golgi glycoprotein 1a
chr3_-_25361866 0.17 ENSDART00000147322
grb2b
growth factor receptor-bound protein 2b
chr15_+_2556689 0.17 ENSDART00000063329
cux1b
cut-like homeobox 1b
chr10_-_42279805 0.17 ENSDART00000132976
ess2
ess-2 splicing factor homolog
chr23_+_44937093 0.17

chr11_-_25495239 0.17

chr23_+_16848213 0.16 ENSDART00000104791
zgc:153722
zgc:153722
chr5_-_18458827 0.16 ENSDART00000145210
ankle2
ankyrin repeat and LEM domain containing 2
chr23_+_2847589 0.16 ENSDART00000156954
plcg1
phospholipase C, gamma 1
chr21_+_5027576 0.16 ENSDART00000139288
si:dkey-121h17.7
si:dkey-121h17.7
chr9_-_32240567 0.16

chr11_-_7786415 0.16 ENSDART00000154569
CR450813.1
ENSDARG00000097035
chr1_+_29027527 0.16 ENSDART00000142184
zic2b
zic family member 2 (odd-paired homolog, Drosophila) b
chr3_-_33812379 0.15

chr19_-_7522951 0.15 ENSDART00000003544
gabpb2a
GA binding protein transcription factor, beta subunit 2a
chr14_+_29601046 0.14 ENSDART00000143763
fam149a
family with sequence similarity 149 member A
chr9_+_55963230 0.14

chr19_-_11397220 0.14 ENSDART00000104933
eepd1
endonuclease/exonuclease/phosphatase family domain containing 1
chr6_-_1638631 0.13 ENSDART00000087039
ENSDARG00000015563
ENSDARG00000015563
chr25_-_34596585 0.13 ENSDART00000171659
zgc:162611
zgc:162611
chr3_-_35411760 0.13 ENSDART00000022147
ndufab1b
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1b
chr21_+_32046764 0.13

chr2_-_41713521 0.13 ENSDART00000084597
d2hgdh
D-2-hydroxyglutarate dehydrogenase
chr10_-_42691422 0.12 ENSDART00000039187
march5l
membrane-associated ring finger (C3HC4) 5, like
chr1_-_19072200 0.12

chr1_+_34741292 0.12 ENSDART00000109678
usp38
ubiquitin specific peptidase 38
chr1_+_19071918 0.12 ENSDART00000138276
ENSDARG00000077648
ENSDARG00000077648
chr25_+_20021806 0.11 ENSDART00000104304
bpgm
2,3-bisphosphoglycerate mutase
chr14_+_29601252 0.11 ENSDART00000143763
fam149a
family with sequence similarity 149 member A
chr6_+_54798741 0.11

chr18_-_199009 0.11

chr1_+_9633924 0.11 ENSDART00000029774
tmem55bb
transmembrane protein 55Bb
chr25_-_34596670 0.11 ENSDART00000171659
zgc:162611
zgc:162611
chr21_+_812425 0.11 ENSDART00000006419
ENSDART00000133976
txnl1
thioredoxin-like 1
chr16_-_26798351 0.11

chr16_+_34157948 0.11 ENSDART00000140552
tcea3
transcription elongation factor A (SII), 3
chr22_-_29938022 0.10

chr22_-_6772249 0.10 ENSDART00000108883
si:ch1073-188e1.1
si:ch1073-188e1.1
chr19_-_27092958 0.10

chr11_+_17849528 0.10 ENSDART00000020283
rpusd4
RNA pseudouridylate synthase domain containing 4
chr6_-_19666829 0.10 ENSDART00000083085
mtmr14
myotubularin related protein 14
chr10_-_22181059 0.10 ENSDART00000006173
cldn7b
claudin 7b
chr17_-_43896998 0.10 ENSDART00000156513
BX465227.1
ENSDARG00000097825
chr3_-_25361708 0.10 ENSDART00000147322
grb2b
growth factor receptor-bound protein 2b
chr16_+_28643677 0.10 ENSDART00000149306
nmt2
N-myristoyltransferase 2
chr10_-_5846612 0.10 ENSDART00000161096
ankrd55
ankyrin repeat domain 55
chr23_-_29579049 0.10 ENSDART00000165744
kif1b
kinesin family member 1B
chr10_-_42279667 0.09 ENSDART00000132976
ess2
ess-2 splicing factor homolog
chr4_-_18976343 0.09

chr22_-_27252706 0.09 ENSDART00000019442
xpnpep1
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr16_+_11027467 0.09 ENSDART00000172949
pou2f2a
POU class 2 homeobox 2a
chr7_+_22540012 0.09

chr21_+_27152225 0.08 ENSDART00000125349
bada
BCL2-associated agonist of cell death a
chr19_+_40792676 0.08 ENSDART00000110699
vps50
VPS50 EARP/GARPII complex subunit
chr5_+_53229583 0.08 ENSDART00000171107
naa38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr2_-_58230370 0.08

chr5_+_58883486 0.08 ENSDART00000055350
dtx2
deltex 2, E3 ubiquitin ligase
chr11_+_42184011 0.08 ENSDART00000161332
zgc:110286
zgc:110286
chr12_+_33793468 0.08 ENSDART00000130853
mfsd13a
major facilitator superfamily domain containing 13A
chr8_-_53553764 0.08 ENSDART00000157521
actr8
ARP8 actin related protein 8 homolog
chr6_-_32059004 0.08 ENSDART00000139055
efcab7
EF-hand calcium binding domain 7
chr10_+_3053045 0.08 ENSDART00000028870
ube2l3a
ubiquitin-conjugating enzyme E2L 3a
chr1_+_9634016 0.07 ENSDART00000029774
tmem55bb
transmembrane protein 55Bb
chr7_+_39393052 0.07 ENSDART00000146171
zgc:158564
zgc:158564
chr2_+_1260457 0.07

chr3_-_25361754 0.07 ENSDART00000147322
grb2b
growth factor receptor-bound protein 2b
chr25_+_18997277 0.06 ENSDART00000154066
isg20
interferon stimulated exonuclease gene
chr11_-_16017396 0.06 ENSDART00000081062
arpc4l
actin related protein 2/3 complex, subunit 4, like
chr22_-_6772204 0.06 ENSDART00000108883
si:ch1073-188e1.1
si:ch1073-188e1.1
chr24_+_20782714 0.06 ENSDART00000144883
fam162a
family with sequence similarity 162, member A
chr16_+_12726556 0.06

chr19_+_40792612 0.05 ENSDART00000017917
vps50
VPS50 EARP/GARPII complex subunit
chr7_+_39393106 0.05 ENSDART00000047271
ENSDART00000113458
zgc:158564
zgc:158564
chr13_-_5952897 0.04 ENSDART00000099224
dld
deltaD
chr14_-_43204831 0.04 ENSDART00000122339
gar1
GAR1 homolog, ribonucleoprotein
chr11_+_42184049 0.04 ENSDART00000056048
si:ch1073-165f9.2
si:ch1073-165f9.2
chr1_-_44513922 0.03 ENSDART00000014727
ddx39aa
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa
chr16_-_21891328 0.03 ENSDART00000123597
ENSDARG00000089032
ENSDARG00000089032
chr6_-_55332828 0.03

chr13_+_40560230 0.03 ENSDART00000146112
hps1
Hermansky-Pudlak syndrome 1
chr11_+_3939876 0.03 ENSDART00000122953
gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr17_+_30431395 0.03 ENSDART00000153939
lpin1
lipin 1
chr2_+_48220021 0.03 ENSDART00000056291
klf6b
Kruppel-like factor 6b
chr21_+_16969092 0.03 ENSDART00000101246
vps29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr4_-_9195261 0.02 ENSDART00000080943
hcfc2
host cell factor C2
chr16_-_36794503 0.02 ENSDART00000133310
pik3r4
phosphoinositide-3-kinase, regulatory subunit 4
chr10_-_42691305 0.02 ENSDART00000171404
march5l
membrane-associated ring finger (C3HC4) 5, like
chr22_+_4408184 0.02 ENSDART00000113811
CU570881.1
ENSDARG00000078024
chr14_-_33604914 0.01 ENSDART00000168546
zdhhc24
zinc finger, DHHC-type containing 24
chr7_-_26243985 0.01 ENSDART00000173617
eif4a1a
eukaryotic translation initiation factor 4A1A
chr6_-_1638559 0.01 ENSDART00000087039
ENSDARG00000015563
ENSDARG00000015563
chr12_-_6029653 0.01 ENSDART00000002583
aarsd1
alanyl-tRNA synthetase domain containing 1
chr2_+_2583038 0.01

chr15_+_2556736 0.01 ENSDART00000063329
cux1b
cut-like homeobox 1b
chr12_-_29190576 0.01 ENSDART00000153458
sh2d4bb
SH2 domain containing 4Bb
chr19_-_30767032 0.01 ENSDART00000146847
khdrbs1b
KH domain containing, RNA binding, signal transduction associated 1b
chr1_+_264808 0.01 ENSDART00000139438
cenpe
centromere protein E
chr2_-_57723042 0.00 ENSDART00000143973
sf3a2
splicing factor 3a, subunit 2
chr3_+_59589031 0.00 ENSDART00000108647
alyref
Aly/REF export factor
chr13_-_743812 0.00 ENSDART00000167256
ENSDARG00000102651
ENSDARG00000102651
chr6_-_6965908 0.00 ENSDART00000041304
atg3
autophagy related 3
chr14_-_46646688 0.00

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.4 GO:0022602 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698)
0.1 0.3 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.6 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 0.5 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.1 0.2 GO:0035474 selective angioblast sprouting(GO:0035474)
0.1 0.2 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:0090344 negative regulation of cell aging(GO:0090344)
0.0 1.0 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.1 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 0.1 GO:0018377 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.0 0.5 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.3 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.3 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.2 GO:0045199 maintenance of cell polarity(GO:0030011) maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.1 GO:0090199 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.7 GO:0006865 amino acid transport(GO:0006865)
0.0 0.0 GO:1903232 melanosome assembly(GO:1903232)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.3 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.1 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.7 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.0 GO:0031085 BLOC-3 complex(GO:0031085)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.7 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.1 0.3 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 0.4 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 0.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.3 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.0 0.6 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 1.0 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.0 0.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.2 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.6 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)