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Results for msx2b

Z-value: 0.83

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Transcription factors associated with msx2b

Gene Symbol Gene ID Gene Info
msx2b
ENSDARG00000101023 muscle segment homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
msx2bdr10_dc_chr21_-_41286846_41286877-0.853.0e-05Click!

Activity profile of msx2b motif

Sorted Z-values of msx2b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of msx2b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr13_-_49934440 3.51 ENSDART00000034541
gpatch11
G patch domain containing 11
chr10_-_25246786 2.84 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr14_-_880799 2.59 ENSDART00000031992
rgs14a
regulator of G protein signaling 14a
chr5_-_8712068 2.19 ENSDART00000134896
ENSDART00000147000
lrp13
low-density lipoprotein receptor related-protein 13
chr16_-_24727689 1.95 ENSDART00000167121
fxyd6l
FXYD domain containing ion transport regulator 6 like
chr5_-_8712114 1.73 ENSDART00000134896
ENSDART00000147000
lrp13
low-density lipoprotein receptor related-protein 13
chr19_-_48327666 1.71

chr13_+_33331767 1.59 ENSDART00000177841
zgc:136302
zgc:136302
chr20_-_3220106 1.45 ENSDART00000123331
spint1b
serine peptidase inhibitor, Kunitz type 1 b
chr7_+_16771283 1.44 ENSDART00000171275
CU929054.1
ENSDARG00000102605
chr2_-_37418967 1.41 ENSDART00000015723
prkci
protein kinase C, iota
chr10_+_11014479 1.36 ENSDART00000064992
cdc37l1
cell division cycle 37-like 1
chr19_+_14132374 1.31 ENSDART00000164696
tmem222b
transmembrane protein 222b
chr17_+_50622734 1.28 ENSDART00000049464
fermt2
fermitin family member 2
chr20_-_23527234 1.28 ENSDART00000004625
zar1
zygote arrest 1
chr11_+_25302044 1.23 ENSDART00000035602
cxxc1b
CXXC finger protein 1b
chr18_+_6417959 1.21 ENSDART00000110892
b4galnt3b
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr14_+_33167424 1.20 ENSDART00000038128
mcts1
malignant T cell amplified sequence 1
chr2_+_46210971 1.19

chr2_+_46210909 1.13

chr22_+_4734033 1.08 ENSDART00000158846
mibp
muscle-specific beta 1 integrin binding protein
chr15_-_23786063 1.08 ENSDART00000109318
zc3h4
zinc finger CCCH-type containing 4
chr21_-_37750338 1.07 ENSDART00000133585
fam114a2
family with sequence similarity 114, member A2
chr12_-_17741310 1.05 ENSDART00000166604
baiap2l1a
BAI1-associated protein 2-like 1a
chr17_+_32670368 1.05 ENSDART00000142449
ctsba
cathepsin Ba
KN149710v1_+_38638 1.04

chr21_-_19883182 1.04 ENSDART00000065670
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr3_-_33296077 1.04 ENSDART00000075495
rpl23
ribosomal protein L23
chr2_+_49343278 1.02 ENSDART00000175147
sema6ba
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba
chr10_-_8088063 1.01 ENSDART00000099031
zgc:136254
zgc:136254
chr15_-_23849212 0.99 ENSDART00000059354
rad1
RAD1 homolog (S. pombe)
chr14_+_20941526 0.97 ENSDART00000138551
smim19
small integral membrane protein 19
chr7_+_13238684 0.94 ENSDART00000053535
arih1l
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like
chr5_-_53907908 0.93 ENSDART00000158069
ssna1
Sjogren syndrome nuclear autoantigen 1
chr3_-_31487744 0.92 ENSDART00000124559
moto
minamoto
chr8_-_1833095 0.92 ENSDART00000114476
ENSDART00000091235
ENSDART00000140077
pi4kab
phosphatidylinositol 4-kinase, catalytic, alpha b
chr20_-_3292418 0.89 ENSDART00000099315
cebpz
CCAAT/enhancer binding protein (C/EBP), zeta
chr23_+_44730111 0.88 ENSDART00000177271
trappc1
trafficking protein particle complex 1
chr19_-_12473163 0.88 ENSDART00000165518
ptpn2b
protein tyrosine phosphatase, non-receptor type 2, b
chr22_-_510040 0.87 ENSDART00000140101
ccnd3
cyclin D3
chr3_+_56882443 0.85

chr21_-_19883409 0.84 ENSDART00000065670
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr8_-_16689736 0.82 ENSDART00000049676
depdc1a
DEP domain containing 1a
chr24_+_25871962 0.82 ENSDART00000137851
tfr1b
transferrin receptor 1b
chr25_-_34596670 0.81 ENSDART00000171659
zgc:162611
zgc:162611
chr8_+_19945820 0.81 ENSDART00000134124
znf692
zinc finger protein 692
chr2_-_55584106 0.79 ENSDART00000169382
ENSDART00000097874
tpm4b
tropomyosin 4b
chr15_-_34550732 0.76 ENSDART00000139934
agmo
alkylglycerol monooxygenase
chr19_-_7522951 0.76 ENSDART00000003544
gabpb2a
GA binding protein transcription factor, beta subunit 2a
chr6_-_54425831 0.75 ENSDART00000017230
snrpc
small nuclear ribonucleoprotein polypeptide C
chr19_+_7072033 0.71 ENSDART00000158758
ENSDART00000160482
kifc1
kinesin family member C1
chr21_-_39616469 0.69 ENSDART00000026766
aldocb
aldolase C, fructose-bisphosphate, b
chr3_-_2041373 0.65 ENSDART00000146552
polr2f
polymerase (RNA) II (DNA directed) polypeptide F
chr12_+_10078043 0.65 ENSDART00000152369
si:dkeyp-118b1.2
si:dkeyp-118b1.2
chr7_-_66470152 0.65 ENSDART00000021317
ctr9
CTR9 homolog, Paf1/RNA polymerase II complex component
chr3_+_56882467 0.64

chr22_+_2575708 0.63

chr2_-_37419017 0.62 ENSDART00000015723
prkci
protein kinase C, iota
chr20_+_6545194 0.62 ENSDART00000159829
si:ch211-191a24.4
si:ch211-191a24.4
chr18_-_35861482 0.61 ENSDART00000088488
opa3
optic atrophy 3
chr11_-_6870835 0.61 ENSDART00000007204
ddx49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr11_-_6442547 0.60 ENSDART00000137879
zgc:162969
zgc:162969
chr23_+_2104589 0.60

chr22_-_21820673 0.60 ENSDART00000105564
aes
amino-terminal enhancer of split
chr25_-_5805538 0.59

chr21_-_21477462 0.58 ENSDART00000031205
pvrl3b
poliovirus receptor-related 3b
chr2_-_12852199 0.58

chr21_-_14719281 0.58 ENSDART00000067004
phpt1
phosphohistidine phosphatase 1
chr11_-_6442490 0.57 ENSDART00000137879
zgc:162969
zgc:162969
chr23_-_77607 0.57

chr19_+_40590165 0.56 ENSDART00000049147
rbm48
RNA binding motif protein 48
chr14_+_11864388 0.56 ENSDART00000146521
rhogd
ras homolog gene family, member Gd
chr15_+_47207100 0.56 ENSDART00000154481
stard10
StAR-related lipid transfer (START) domain containing 10
chr23_+_39718769 0.55 ENSDART00000034690
otud3
OTU deubiquitinase 3
chr18_-_17158425 0.55 ENSDART00000141873
zc3h18
zinc finger CCCH-type containing 18
chr23_-_25208472 0.54 ENSDART00000103989
ENSDART00000160278
idh3g
isocitrate dehydrogenase 3 (NAD+) gamma
chr7_-_66470118 0.54 ENSDART00000021317
ctr9
CTR9 homolog, Paf1/RNA polymerase II complex component
chr7_+_23752492 0.53 ENSDART00000141165
tinf2
TERF1 (TRF1)-interacting nuclear factor 2
chr20_-_3292250 0.52 ENSDART00000099315
cebpz
CCAAT/enhancer binding protein (C/EBP), zeta
chr23_-_31986679 0.52 ENSDART00000085054
mtfr2
mitochondrial fission regulator 2
chr17_-_7377094 0.51

chr8_-_53593850 0.51

chr23_-_39879096 0.51 ENSDART00000159519
ENSDARG00000102199
ENSDARG00000102199
chr4_-_25179188 0.51 ENSDART00000066929
taf3
TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto
chr3_+_30956719 0.50 ENSDART00000129564
si:dkey-66i24.8
si:dkey-66i24.8
chr5_+_24378828 0.50 ENSDART00000111302
rhbdd3
rhomboid domain containing 3
chr19_+_12487051 0.47 ENSDART00000052238
ENSDART00000013865
seh1l
SEH1-like (S. cerevisiae)
chr14_-_880729 0.46 ENSDART00000165211
rgs14a
regulator of G protein signaling 14a
chr5_-_66502280 0.45 ENSDART00000065264
cdca5
cell division cycle associated 5
chr15_-_25431916 0.45 ENSDART00000047471
cluha
clustered mitochondria (cluA/CLU1) homolog a
chr4_-_16893974 0.45 ENSDART00000124627
strap
serine/threonine kinase receptor associated protein
chr9_-_41352000 0.44 ENSDART00000059667
wdr75
WD repeat domain 75
chr9_-_2522639 0.44 ENSDART00000137706
scrn3
secernin 3
chr1_+_40428722 0.43 ENSDART00000145272
lrpap1
low density lipoprotein receptor-related protein associated protein 1
chr1_-_27395825 0.42 ENSDART00000170779
snapc3
small nuclear RNA activating complex, polypeptide 3
chr20_-_40357240 0.42

chr2_-_41722058 0.42 ENSDART00000022643
znf622
zinc finger protein 622
chr4_-_11811833 0.41 ENSDART00000014153
cyb5r3
cytochrome b5 reductase 3
chr13_-_49934345 0.40 ENSDART00000034541
gpatch11
G patch domain containing 11
chr8_+_293186 0.40 ENSDART00000164099
ENSDART00000165472
snx2
sorting nexin 2
chr2_+_9957535 0.39 ENSDART00000018524
pcyt1aa
phosphate cytidylyltransferase 1, choline, alpha a
chr8_-_26773755 0.38 ENSDART00000139787
kazna
kazrin, periplakin interacting protein a
chr18_-_19016801 0.37 ENSDART00000129776
vwa9
von Willebrand factor A domain containing 9
chr2_-_43274603 0.36 ENSDART00000132346
ENSDART00000075347
lrrc6
leucine rich repeat containing 6
chr11_+_17849528 0.35 ENSDART00000020283
rpusd4
RNA pseudouridylate synthase domain containing 4
chr21_-_2211701 0.34 ENSDART00000175686
si:dkey-50i6.6
si:dkey-50i6.6
chr20_-_51373292 0.33 ENSDART00000027836
ENSDART00000114407
rbm25b
RNA binding motif protein 25b
chr22_-_29695242 0.32

chr1_+_33471274 0.31 ENSDART00000046094
arl6
ADP-ribosylation factor-like 6
chr23_-_31986571 0.30 ENSDART00000135526
mtfr2
mitochondrial fission regulator 2
chr25_+_386868 0.29

chr24_+_25872051 0.27 ENSDART00000137851
tfr1b
transferrin receptor 1b
chr9_-_35073289 0.25 ENSDART00000011163
asmtl
acetylserotonin O-methyltransferase-like
chr14_+_33167301 0.25 ENSDART00000038128
mcts1
malignant T cell amplified sequence 1
chr8_-_53593880 0.25 ENSDART00000015554
ubiad1
UbiA prenyltransferase domain containing 1
chr9_-_50106442 0.23

chr8_-_38285034 0.23 ENSDART00000125920
pdlim2
PDZ and LIM domain 2 (mystique)
chr7_-_13109764 0.22 ENSDART00000091616
sdhaf2
succinate dehydrogenase complex assembly factor 2
chr17_+_12504341 0.22 ENSDART00000139918
gpn1
GPN-loop GTPase 1
chr18_-_50108685 0.22

chr16_+_54350976 0.19 ENSDART00000172622
ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr7_-_66469975 0.17 ENSDART00000021317
ctr9
CTR9 homolog, Paf1/RNA polymerase II complex component
chr7_-_39874079 0.17 ENSDART00000173634
wdr60
WD repeat domain 60
chr23_-_31986482 0.16 ENSDART00000135526
mtfr2
mitochondrial fission regulator 2
chr13_-_35924447 0.16 ENSDART00000134955
lgmn
legumain
chr15_+_17138134 0.15 ENSDART00000046648
clptm1
cleft lip and palate associated transmembrane protein 1
chr14_-_6831278 0.14 ENSDART00000054803
trpt1
tRNA phosphotransferase 1
chr9_-_52950815 0.13 ENSDART00000161667
smarcal1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr6_-_52348510 0.12 ENSDART00000142565
eif6
eukaryotic translation initiation factor 6
chr24_+_26183653 0.11 ENSDART00000003884
mynn
myoneurin
chr11_+_29523717 0.11 ENSDART00000088624
ENSDART00000124471
rpgrb
retinitis pigmentosa GTPase regulator b
chr23_-_45265411 0.09

chr15_+_17094877 0.09 ENSDART00000062069
plin2
perilipin 2
chr3_-_13311188 0.09 ENSDART00000080807
fbxw9
F-box and WD repeat domain containing 9
chr1_-_50438531 0.08

chr25_+_35778740 0.08 ENSDART00000073404
zgc:114037
zgc:114037
chr10_+_18919823 0.07 ENSDART00000138334
ppp2r2ab
protein phosphatase 2, regulatory subunit B, alpha b
chr12_-_29118423 0.07 ENSDART00000153175
si:ch211-214e3.5
si:ch211-214e3.5
chr18_+_5616238 0.05 ENSDART00000163629
dut
deoxyuridine triphosphatase
chr20_-_20455731 0.04 ENSDART00000170488
ENSDART00000047580
hif1ab
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b
chr10_-_13158018 0.04 ENSDART00000164568
musk
muscle, skeletal, receptor tyrosine kinase
chr7_+_15065241 0.03 ENSDART00000045385
mespba
mesoderm posterior ba
chr5_-_12060382 0.03 ENSDART00000133587
wsb2
WD repeat and SOCS box containing 2
chr12_-_27497159 0.01 ENSDART00000066282
dhx8
DEAH (Asp-Glu-Ala-His) box polypeptide 8

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.5 1.5 GO:0002188 translation reinitiation(GO:0002188)
0.5 1.9 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.3 1.4 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.3 0.8 GO:0046485 ether lipid metabolic process(GO:0046485)
0.2 2.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 1.1 GO:0015682 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.2 0.8 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 0.9 GO:0007141 male meiosis I(GO:0007141)
0.2 0.5 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.1 3.0 GO:0008354 germ cell migration(GO:0008354)
0.1 1.1 GO:2000251 regulation of actin cytoskeleton reorganization(GO:2000249) positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 1.2 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.4 GO:0010984 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916) regulation of lipoprotein particle clearance(GO:0010984) negative regulation of lipoprotein particle clearance(GO:0010985)
0.1 0.4 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 2.0 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.5 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.5 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.5 GO:0006999 nuclear pore organization(GO:0006999)
0.1 0.9 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 0.3 GO:0042373 vitamin K metabolic process(GO:0042373) cellular response to fluid shear stress(GO:0071498)
0.1 0.2 GO:0034553 mitochondrial electron transport, succinate to ubiquinone(GO:0006121) respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.2 GO:0030279 negative regulation of ossification(GO:0030279)
0.0 1.0 GO:0000266 mitochondrial fission(GO:0000266)
0.0 1.3 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 0.3 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.0 0.5 GO:0016233 telomere capping(GO:0016233)
0.0 0.6 GO:1902622 regulation of neutrophil migration(GO:1902622)
0.0 1.4 GO:0050821 protein stabilization(GO:0050821)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0010889 regulation of sequestering of triglyceride(GO:0010889) positive regulation of sequestering of triglyceride(GO:0010890) sequestering of triglyceride(GO:0030730)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 1.0 GO:0000077 DNA damage checkpoint(GO:0000077)
0.0 0.9 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.6 GO:0050881 multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881)
0.0 1.0 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.7 GO:0090307 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 0.1 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.0 0.5 GO:0048634 regulation of muscle organ development(GO:0048634)
0.0 0.9 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.3 GO:0061512 protein localization to cilium(GO:0061512)
0.0 1.0 GO:0031101 fin regeneration(GO:0031101)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.2 1.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 1.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.4 GO:0019185 snRNA-activating protein complex(GO:0019185)
0.1 1.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 3.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 0.5 GO:0070187 telosome(GO:0070187)
0.1 1.0 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 0.8 GO:0000243 commitment complex(GO:0000243)
0.1 1.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.9 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665) DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.0 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.1 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 3.0 GO:0030425 dendrite(GO:0030425)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.7 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.9 GO:0036064 ciliary basal body(GO:0036064)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.3 3.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 0.9 GO:1903231 mRNA binding involved in posttranscriptional gene silencing(GO:1903231)
0.2 1.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.2 1.1 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.2 2.8 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.2 2.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 0.9 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2 0.8 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.6 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.1 0.5 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 1.9 GO:2001069 glycogen binding(GO:2001069)
0.1 2.0 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.4 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.4 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 0.4 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 3 promoter sequence-specific DNA binding(GO:0001006) RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.1 0.8 GO:0030619 U1 snRNA binding(GO:0030619)
0.1 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.4 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 1.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 1.3 GO:0005178 integrin binding(GO:0005178)
0.0 1.4 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 1.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.7 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.9 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 0.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.1 PID ATR PATHWAY ATR signaling pathway
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 1.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.6 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.5 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 1.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.0 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.5 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends