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Results for mta3

Z-value: 0.40

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Transcription factors associated with mta3

Gene Symbol Gene ID Gene Info
mta3
ENSDARG00000054903 metastasis associated 1 family, member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mta3dr10_dc_chr12_+_25132396_251325770.533.6e-02Click!

Activity profile of mta3 motif

Sorted Z-values of mta3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of mta3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr25_+_33527870 0.97 ENSDART00000011967
anxa2a
annexin A2a
KN149707v1_+_4014 0.86 ENSDART00000168516
cdo1
cysteine dioxygenase, type I
chr19_+_33267939 0.74 ENSDART00000176726
rpl30
ribosomal protein L30
chr18_-_11216447 0.63 ENSDART00000040500
tspan9a
tetraspanin 9a
chr7_-_52283383 0.59 ENSDART00000165649
tcf12
transcription factor 12
chr11_-_32461160 0.58 ENSDART00000155592
pcdh17
protocadherin 17
chr25_-_34638406 0.57 ENSDART00000123853
hist1h4l
histone 1, H4, like
chr19_+_42183946 0.53 ENSDART00000087096
tinagl1
tubulointerstitial nephritis antigen-like 1
chr25_-_2485276 0.52 ENSDART00000154889
ENSDART00000155027
BX957346.1
ENSDARG00000096850
chr16_+_29109050 0.50 ENSDART00000122681
CR848841.1
Nestin
chr12_-_10372055 0.44 ENSDART00000052001
eef2k
eukaryotic elongation factor 2 kinase
chr1_+_52308366 0.41 ENSDART00000108492
inpp4b
inositol polyphosphate-4-phosphatase type II B
chr8_-_19872129 0.41 ENSDART00000129193
trabd2b
TraB domain containing 2B
chr20_-_54645287 0.35 ENSDART00000153389
yy1b
YY1 transcription factor b
chr5_+_68410884 0.34 ENSDART00000153691
CU928129.1
ENSDARG00000097815
chr21_+_44586326 0.29

chr21_-_45595372 0.26 ENSDART00000163982
camlg
calcium modulating ligand
chr14_-_549816 0.26 ENSDART00000168951
fgf2
fibroblast growth factor 2
chr3_-_5318206 0.25 ENSDART00000137105
myh9b
myosin, heavy chain 9b, non-muscle
chr21_+_25150600 0.23 ENSDART00000101147
si:dkey-183i3.5
si:dkey-183i3.5
chr1_+_52308299 0.20 ENSDART00000108492
inpp4b
inositol polyphosphate-4-phosphatase type II B
chr13_-_33527029 0.20

chr16_+_11138879 0.17 ENSDART00000091183
erfl3
Ets2 repressor factor like 3
chr18_+_40364675 0.17 ENSDART00000098791
ENSDART00000049171
sema6dl
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr2_-_59013059 0.16

chr13_-_4238224 0.16 ENSDART00000124716
si:dkeyp-121d4.3
si:dkeyp-121d4.3
chr5_+_65754237 0.15 ENSDART00000170757
kntc1
kinetochore associated 1
chr5_-_21520111 0.14

chr25_-_34601771 0.14 ENSDART00000073457
zgc:194989
zgc:194989
chr6_-_12035327 0.12

chr23_-_25866388 0.10 ENSDART00000138370
BX005414.1
ENSDARG00000094688
chr4_-_13256905 0.10 ENSDART00000026593
ENSDART00000150577
grip1
glutamate receptor interacting protein 1
chr8_+_27536121 0.09 ENSDART00000016696
rhocb
ras homolog family member Cb
chr20_+_54645315 0.08

chr12_-_4351401 0.08

chr5_+_30725475 0.08

chr22_+_26840335 0.06 ENSDART00000158756
crebbpa
CREB binding protein a
chr8_-_23250112 0.06

chr25_-_2485217 0.04 ENSDART00000154889
ENSDART00000155027
BX957346.1
ENSDARG00000096850
chr11_-_44280978 0.04 ENSDART00000099568
gpr137bb
G protein-coupled receptor 137Bb
chr14_-_2451650 0.04 ENSDART00000111748
pcdhb
protocadherin b
chr2_-_55971357 0.03 ENSDART00000154701
ENSDART00000154107
si:ch211-178n15.1
si:ch211-178n15.1
chr2_-_43318809 0.02 ENSDART00000132588
crema
cAMP responsive element modulator a
chr20_-_54645903 0.00 ENSDART00000038745
yy1b
YY1 transcription factor b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.4 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.3 GO:0030323 respiratory tube development(GO:0030323) lung development(GO:0030324)
0.0 0.4 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.2 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 0.6 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.1 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 GO:0005604 basement membrane(GO:0005604)
0.0 0.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.1 0.6 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.9 GO:0016702 ferrous iron binding(GO:0008198) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends