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Results for mybl1

Z-value: 1.46

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Transcription factors associated with mybl1

Gene Symbol Gene ID Gene Info
mybl1
ENSDARG00000030999 v-myb avian myeloblastosis viral oncogene homolog-like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mybl1dr10_dc_chr24_+_23646663_23646747-0.533.6e-02Click!

Activity profile of mybl1 motif

Sorted Z-values of mybl1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of mybl1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr21_+_25740782 4.69 ENSDART00000021620
cldnd
claudin d
chr14_-_35552296 3.77 ENSDART00000052648
tmem144b
transmembrane protein 144b
chr14_+_30434569 3.63 ENSDART00000023054
atl3
atlastin 3
chr22_-_8144696 3.37 ENSDART00000156571
si:ch73-44m9.3
si:ch73-44m9.3
chr23_+_4409342 3.34 ENSDART00000136287
mybl2a
v-myb avian myeloblastosis viral oncogene homolog-like 2a
chr22_-_28828375 3.22 ENSDART00000104880
ENSDART00000005112
si:dkeyp-34c12.1
si:dkeyp-34c12.1
chr13_-_42548129 3.01 ENSDART00000169083
lrrfip2
leucine rich repeat (in FLII) interacting protein 2
chr21_+_28710341 3.01 ENSDART00000014058
zgc:100829
zgc:100829
chr1_+_50893368 2.99 ENSDART00000152789
etaa1
ETAA1, ATR kinase activator
chr18_+_17545564 2.83 ENSDART00000061007
mt2
metallothionein 2
chr22_+_31073990 2.71 ENSDART00000111561
zmp:0000000735
zmp:0000000735
chr20_+_30476065 2.65 ENSDART00000062441
rnaseh1
ribonuclease H1
chr14_+_30434751 2.62 ENSDART00000139975
atl3
atlastin 3
chr5_+_56896961 2.58

chr22_-_8144599 2.56 ENSDART00000156571
si:ch73-44m9.3
si:ch73-44m9.3
chr1_+_45784486 2.47

chr22_-_7976467 2.35 ENSDART00000162028
sc:d217
sc:d217
chr3_+_22914624 2.26 ENSDART00000157090
ENSDART00000103858
b4galnt2.2
beta-1,4-N-acetyl-galactosaminyl transferase 2, tandem duplicate 2
chr3_-_3646681 2.16 ENSDART00000165648
ENSDART00000046454
ENSDART00000115282
ENSDART00000164463
ENSDARG00000076771
ENSDARG00000076771
chr18_-_16947996 2.14 ENSDART00000100117
znf143b
zinc finger protein 143b
chr18_-_16948109 2.08 ENSDART00000100117
znf143b
zinc finger protein 143b
chr6_-_46740359 2.05 ENSDART00000011970
zgc:66479
zgc:66479
chr7_-_15942989 1.94 ENSDART00000173739
btr04
bloodthirsty-related gene family, member 4
chr11_-_22210506 1.91 ENSDART00000146873
tmem183a
transmembrane protein 183A
chr3_+_22914688 1.88 ENSDART00000156472
b4galnt2.2
beta-1,4-N-acetyl-galactosaminyl transferase 2, tandem duplicate 2
chr20_+_2100836 1.85

chr2_-_24909546 1.84 ENSDART00000170283
crsp7
cofactor required for Sp1 transcriptional activation, subunit 7
chr7_-_15943107 1.80 ENSDART00000173492
btr04
bloodthirsty-related gene family, member 4
chr21_-_26655258 1.79 ENSDART00000149702
ENSDART00000149840
bscl2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr15_-_24007305 1.74 ENSDART00000002824
appbp2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr21_+_28710269 1.70 ENSDART00000014058
zgc:100829
zgc:100829
chr21_+_28710424 1.63 ENSDART00000014058
zgc:100829
zgc:100829
chr1_-_42915971 1.58

chr2_-_24909432 1.54 ENSDART00000170283
crsp7
cofactor required for Sp1 transcriptional activation, subunit 7
chr6_-_22311576 1.44

chr6_-_6818607 1.44 ENSDART00000151822
tuba8l4
tubulin, alpha 8 like 4
chr12_+_31523147 1.43 ENSDART00000153129
dnmbp
dynamin binding protein
chr1_+_35253862 1.40 ENSDART00000139636
zgc:152968
zgc:152968
chr3_+_14421976 1.39 ENSDART00000171731
znf653
zinc finger protein 653
chr20_+_30475949 1.34 ENSDART00000148242
rnaseh1
ribonuclease H1
chr6_-_9394499 1.34 ENSDART00000013066
ercc3
excision repair cross-complementation group 3
chr17_-_43632707 1.34 ENSDART00000136431
rtkn2a
rhotekin 2a
chr20_+_5022501 1.31 ENSDART00000162678
si:dkey-60a16.1
si:dkey-60a16.1
chr10_-_13549869 1.30

chr2_+_30497550 1.29 ENSDART00000125933
fam173b
family with sequence similarity 173, member B
chr13_+_15571152 1.29 ENSDART00000135960
trmt61a
tRNA methyltransferase 61A
chr14_+_6228658 1.23 ENSDART00000055961
thg1l
tRNA-histidine guanylyltransferase 1-like
chr1_+_44248486 1.21 ENSDART00000067621
vps37c
vacuolar protein sorting 37 homolog C (S. cerevisiae)
chr21_-_19879125 1.18 ENSDART00000164317
eri1
exoribonuclease 1
chr13_-_37043725 1.13

chr2_+_30497691 1.11 ENSDART00000125933
fam173b
family with sequence similarity 173, member B
chr14_+_7596207 1.10 ENSDART00000113299
zgc:110843
zgc:110843
chr5_+_56896748 1.09

chr24_-_20812363 1.07 ENSDART00000142080
kpna1
karyopherin alpha 1 (importin alpha 5)
chr20_-_47576872 1.07 ENSDART00000067776
rab10
RAB10, member RAS oncogene family
chr12_+_31523411 1.06 ENSDART00000153129
dnmbp
dynamin binding protein
chr11_+_25443646 1.05 ENSDART00000121478
otud5b
OTU deubiquitinase 5b
chr23_-_539640 1.03 ENSDART00000128788
mtg2
mitochondrial ribosome-associated GTPase 2
chr20_+_7337986 1.03 ENSDART00000140222
dsg2.1
desmoglein 2, tandem duplicate 1
chr24_+_14095601 1.01 ENSDART00000124740
ncoa2
nuclear receptor coactivator 2
chr5_-_39440181 1.00 ENSDART00000157755
cds1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr23_+_33792005 0.96 ENSDART00000024695
dazap2
DAZ associated protein 2
chr23_+_40070965 0.96 ENSDART00000166539
fyco1a
FYVE and coiled-coil domain containing 1a
chr16_-_31386496 0.95

chr6_-_7854902 0.95

chr7_-_24778134 0.94 ENSDART00000135179
arl2
ADP-ribosylation factor-like 2
chr3_-_6833379 0.93 ENSDART00000123724
atg4db
autophagy related 4D, cysteine peptidase b
chr15_-_24007488 0.92 ENSDART00000002824
appbp2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr8_+_44448437 0.88 ENSDART00000143807
mhc1laa
major histocompatibility complex class I LAA
chr20_+_31375136 0.86

chr12_+_28685081 0.83 ENSDART00000022724
pnpo
pyridoxamine 5'-phosphate oxidase
chr14_+_35552581 0.80 ENSDART00000135079
zgc:63568
zgc:63568
chr22_-_28828300 0.77 ENSDART00000104880
si:dkeyp-34c12.1
si:dkeyp-34c12.1
chr17_+_19461192 0.77 ENSDART00000024194
kif11
kinesin family member 11
chr2_+_20655215 0.75

chr6_-_17903824 0.72 ENSDART00000170369
nol11
nucleolar protein 11
chr23_+_44937093 0.70

chr15_-_24007354 0.68 ENSDART00000002824
appbp2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr20_+_31375056 0.67

chr21_+_28710522 0.66 ENSDART00000137874
zgc:100829
zgc:100829
chr3_-_14421675 0.63 ENSDART00000137197
swsap1
SWIM-type zinc finger 7 associated protein 1
chr23_-_36469779 0.57 ENSDART00000168246
spryd3
SPRY domain containing 3
chr17_-_1949701 0.54 ENSDART00000013093
ENSDART00000168231
ENSDART00000166833
zfyve19
zinc finger, FYVE domain containing 19
chr22_-_20695416 0.53 ENSDART00000105532
oaz1a
ornithine decarboxylase antizyme 1a
chr13_+_31390033 0.53 ENSDART00000086018
pcnxl4
pecanex-like 4 (Drosophila)
chr20_+_5022399 0.50 ENSDART00000053883
si:dkey-60a16.1
si:dkey-60a16.1
chr20_-_26517489 0.48

chr7_+_22538844 0.44 ENSDART00000020212
sf1
splicing factor 1
chr5_+_31382951 0.44 ENSDART00000007458
ppp6c
protein phosphatase 6, catalytic subunit
chr13_-_42547873 0.39 ENSDART00000169083
lrrfip2
leucine rich repeat (in FLII) interacting protein 2
chr16_-_20044830 0.38

chr7_+_51541162 0.36 ENSDART00000174120
si:ch211-122f10.4
si:ch211-122f10.4
chr19_-_33356861 0.33 ENSDART00000137611
azin1b
antizyme inhibitor 1b
chr20_+_31372117 0.29

chr3_-_14421728 0.29 ENSDART00000137197
swsap1
SWIM-type zinc finger 7 associated protein 1
chr18_-_5619309 0.26 ENSDART00000177705
CABZ01081638.1
ENSDARG00000107008
chr9_-_35003703 0.26

chr7_-_31650421 0.24 ENSDART00000146720
lin7c
lin-7 homolog C (C. elegans)
chr14_+_46621228 0.23 ENSDART00000173248
si:ch211-276i12.11
si:ch211-276i12.11
chr12_+_31523317 0.20 ENSDART00000153129
dnmbp
dynamin binding protein
chr24_+_17001271 0.18 ENSDART00000149744
mllt10
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10
chr24_+_14070379 0.17 ENSDART00000004664
tram1
translocation associated membrane protein 1
chr5_+_40910195 0.16 ENSDART00000134317
vcp
valosin containing protein
chr24_-_30924897 0.15 ENSDART00000168540
ptbp2a
polypyrimidine tract binding protein 2a
chr1_+_35253821 0.14 ENSDART00000179634
zgc:152968
zgc:152968
chr5_-_39440105 0.07 ENSDART00000157755
cds1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr16_+_24046933 0.07

chr24_+_17001576 0.04 ENSDART00000149744
mllt10
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10
chr23_-_18131038 0.00 ENSDART00000173385
zgc:92287
zgc:92287

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.0 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.5 4.0 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.5 3.8 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.4 4.1 GO:0030259 lipid glycosylation(GO:0030259)
0.4 2.8 GO:0010574 vascular endothelial growth factor production(GO:0010573) regulation of vascular endothelial growth factor production(GO:0010574) positive regulation of vascular endothelial growth factor production(GO:0010575)
0.3 1.0 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.2 0.8 GO:0042823 water-soluble vitamin biosynthetic process(GO:0042364) pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.2 1.3 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.2 4.7 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.2 0.7 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.2 0.9 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.1 6.4 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 1.0 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.4 GO:0044878 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.1 0.3 GO:1902047 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 0.8 GO:0034389 lipid particle organization(GO:0034389)
0.1 1.1 GO:0098926 postsynaptic signal transduction(GO:0098926)
0.1 1.1 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.1 1.2 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 1.2 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.1 0.2 GO:2000058 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.1 0.5 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 1.3 GO:0030488 tRNA methylation(GO:0030488)
0.0 1.2 GO:0006400 tRNA modification(GO:0006400)
0.0 0.8 GO:0090307 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 0.2 GO:0060729 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.0 0.3 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.4 GO:0001878 response to yeast(GO:0001878)
0.0 1.0 GO:0016579 protein deubiquitination(GO:0016579)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0097196 Shu complex(GO:0097196)
0.3 3.4 GO:0070847 core mediator complex(GO:0070847)
0.3 1.3 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.2 1.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 1.2 GO:0000813 ESCRT I complex(GO:0000813)
0.1 3.0 GO:0043596 nuclear replication fork(GO:0043596)
0.1 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 4.7 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 4.1 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 2.7 GO:0005795 Golgi stack(GO:0005795)
0.0 1.0 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.8 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.4 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.1 GO:0005741 mitochondrial outer membrane(GO:0005741)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.0 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 1.2 GO:0070568 guanylyltransferase activity(GO:0070568)
0.3 1.3 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.2 3.8 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.2 1.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.2 4.1 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 0.3 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.5 GO:0042979 ornithine decarboxylase inhibitor activity(GO:0008073) ornithine decarboxylase regulator activity(GO:0042979)
0.1 1.0 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.8 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 1.1 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 1.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.1 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 2.7 GO:0004527 exonuclease activity(GO:0004527)
0.0 4.7 GO:0042802 identical protein binding(GO:0042802)
0.0 8.3 GO:0003924 GTPase activity(GO:0003924)
0.0 3.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 2.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 4.8 GO:0000989 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 2.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 1.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 1.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.1 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis