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Results for mybl2b

Z-value: 2.61

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Transcription factors associated with mybl2b

Gene Symbol Gene ID Gene Info
mybl2b
ENSDARG00000032264 v-myb avian myeloblastosis viral oncogene homolog-like 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mybl2bdr10_dc_chr11_+_1524965_1525123-0.562.4e-02Click!

Activity profile of mybl2b motif

Sorted Z-values of mybl2b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of mybl2b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr24_+_21495522 9.96 ENSDART00000105925
gtf3ab
general transcription factor IIIA, b
chr4_-_20456825 8.20 ENSDART00000003621
ENSDART00000132356
sinup
siaz-interacting nuclear protein
chr7_+_17695173 7.91 ENSDART00000101601
cth1
cysteine three histidine 1
chr24_-_9857510 7.02 ENSDART00000136274
si:ch211-146l10.7
si:ch211-146l10.7
chr11_+_29299382 6.54

chr22_-_28828375 6.45 ENSDART00000104880
ENSDART00000005112
si:dkeyp-34c12.1
si:dkeyp-34c12.1
chr10_+_32107014 6.40 ENSDART00000137373
si:ch211-266i6.3
si:ch211-266i6.3
chr7_+_58448953 5.96 ENSDART00000024185
zgc:56231
zgc:56231
chr10_-_26240772 5.87 ENSDART00000131394
fhdc3
FH2 domain containing 3
chr5_-_66145078 5.20 ENSDART00000041441
stip1
stress-induced phosphoprotein 1
chr23_+_19663746 4.53 ENSDART00000170149
slmapb
sarcolemma associated protein b
chr22_-_8144696 4.52 ENSDART00000156571
si:ch73-44m9.3
si:ch73-44m9.3
chr24_-_9865837 4.46 ENSDART00000106244
zgc:171750
zgc:171750
chr5_+_52199662 4.31

chr3_+_16880947 4.29 ENSDART00000080854
stat3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr11_+_29295032 4.19 ENSDART00000112721
BX548000.1
ENSDARG00000079546
chr6_-_31196004 4.00

chr20_+_791374 3.97 ENSDART00000137135
mei4
meiosis-specific, MEI4 homolog (S. cerevisiae)
chr16_-_55210909 3.82 ENSDART00000156533
kdf1a
keratinocyte differentiation factor 1a
chr1_-_53052062 3.74 ENSDART00000162751
xpo1a
exportin 1 (CRM1 homolog, yeast) a
chr7_+_31154984 3.71 ENSDART00000138456
eif3jb
eukaryotic translation initiation factor 3, subunit Jb
chr13_+_22973764 3.69 ENSDART00000110266
pik3ap1
phosphoinositide-3-kinase adaptor protein 1
chr23_-_3568408 3.65 ENSDART00000019667
rnf114
ring finger protein 114
chr14_+_30434569 3.63 ENSDART00000023054
atl3
atlastin 3
chr8_-_30732816 3.58 ENSDART00000098986
gucd1
guanylyl cyclase domain containing 1
chr10_+_16543480 3.57 ENSDART00000121864
slc27a6
solute carrier family 27 (fatty acid transporter), member 6
chr15_+_6462447 3.50 ENSDART00000065824
bace2
beta-site APP-cleaving enzyme 2
chr22_-_8144599 3.46 ENSDART00000156571
si:ch73-44m9.3
si:ch73-44m9.3
chr15_-_24007305 3.40 ENSDART00000002824
appbp2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr13_+_11417882 3.37 ENSDART00000034935
desi2
desumoylating isopeptidase 2
chr7_+_35163845 3.33 ENSDART00000173733
BX294178.2
ENSDARG00000104955
chr24_+_21495482 3.25 ENSDART00000105925
gtf3ab
general transcription factor IIIA, b
chr14_-_47387481 3.23 ENSDART00000031498
ccna2
cyclin A2
chr7_+_26730804 3.22

chr1_+_29919378 3.20 ENSDART00000127670
bora
bora, aurora kinase A activator
chr23_+_30803518 3.20 ENSDART00000134141
asxl1
additional sex combs like transcriptional regulator 1
chr5_+_36066758 3.13 ENSDART00000097686
zgc:153990
zgc:153990
chr16_-_11350009 3.08 ENSDART00000134752
znf526
zinc finger protein 526
chr23_+_30803887 3.05 ENSDART00000134141
asxl1
additional sex combs like transcriptional regulator 1
chr5_+_67157818 3.03 ENSDART00000162301
ENSDART00000159386
si:ch211-271b14.1
si:ch211-271b14.1
chr8_-_44247277 2.98

chr17_+_51655501 2.97 ENSDART00000149807
odc1
ornithine decarboxylase 1
chr1_+_49170632 2.97 ENSDART00000132405
lef1
lymphoid enhancer-binding factor 1
chr13_+_45387478 2.96 ENSDART00000019113
tmem57b
transmembrane protein 57b
chr5_+_36066651 2.96 ENSDART00000097686
zgc:153990
zgc:153990
chr8_-_14571519 2.96 ENSDART00000146175
cep350
centrosomal protein 350
chr4_-_1496779 2.95 ENSDART00000166360
nap1l1
nucleosome assembly protein 1-like 1
chr14_-_23798158 2.94 ENSDART00000172747
si:ch211-277c7.7
si:ch211-277c7.7
chr24_+_25872005 2.94 ENSDART00000137851
tfr1b
transferrin receptor 1b
chr13_+_35799681 2.93 ENSDART00000046115
mfsd2aa
major facilitator superfamily domain containing 2aa
chr25_+_29873412 2.91 ENSDART00000067056
ticrr
TopBP1-interacting, checkpoint, and replication regulator
chr15_-_28636418 2.90 ENSDART00000127845
ssh2a
slingshot protein phosphatase 2a
chr23_+_4409342 2.83 ENSDART00000136287
mybl2a
v-myb avian myeloblastosis viral oncogene homolog-like 2a
chr6_-_43297126 2.83 ENSDART00000154170
frmd4ba
FERM domain containing 4Ba
chr23_-_33811895 2.80 ENSDART00000131680
si:ch211-210c8.7
si:ch211-210c8.7
chr7_+_24119777 2.76 ENSDART00000087494
ENSDART00000125463
haus3
HAUS augmin-like complex, subunit 3
chr13_+_45387708 2.75 ENSDART00000074567
tmem57b
transmembrane protein 57b
chr25_+_27836260 2.75 ENSDART00000149373
aass
aminoadipate-semialdehyde synthase
chr17_-_29706238 2.74 ENSDART00000153865
CT027582.2
ENSDARG00000097817
chr4_-_20456437 2.70 ENSDART00000003621
ENSDART00000132356
sinup
siaz-interacting nuclear protein
chr2_+_9854294 2.65

chr1_-_50395003 2.64 ENSDART00000035150
spast
spastin
chr18_+_47305642 2.64 ENSDART00000009775
rbm7
RNA binding motif protein 7
chr13_+_15571152 2.61 ENSDART00000135960
trmt61a
tRNA methyltransferase 61A
chr24_+_28855974 2.61 ENSDART00000017427
rnpc3
RNA-binding region (RNP1, RRM) containing 3
chr13_+_25234411 2.61 ENSDART00000027428
chuk
conserved helix-loop-helix ubiquitous kinase
chr6_+_60117223 2.56 ENSDART00000008243
prelid3b
PRELI domain containing 3
chr5_+_58564789 2.55 ENSDART00000045518
prkrip1
PRKR interacting protein 1 (IL11 inducible)
chr16_+_38400861 2.54 ENSDART00000133752
elp6
elongator acetyltransferase complex subunit 6
chr3_+_12087549 2.53

chr11_+_19440815 2.51 ENSDART00000005639
thoc7
THO complex 7
chr7_+_24119940 2.48 ENSDART00000108753
poln
polymerase (DNA directed) nu
chr6_+_43452686 2.47 ENSDART00000075521
zgc:113054
zgc:113054
chr20_+_791328 2.47 ENSDART00000137135
mei4
meiosis-specific, MEI4 homolog (S. cerevisiae)
chr18_+_27457678 2.44 ENSDART00000014726
tp53i11b
tumor protein p53 inducible protein 11b
chr15_-_30247084 2.43 ENSDART00000154069
BX322555.4
ENSDARG00000097908
chr1_+_31319012 2.43 ENSDART00000146602
sts
steroid sulfatase (microsomal), isozyme S
chr25_+_35790000 2.42 ENSDART00000152195
si:ch211-113a14.18
si:ch211-113a14.18
chr24_-_36413059 2.41 ENSDART00000062736
coasy
CoA synthase
chr10_+_19059739 2.41 ENSDART00000038674
tmem230a
transmembrane protein 230a
chr4_+_9010972 2.36 ENSDART00000058007
samm50l
sorting and assembly machinery component 50 homolog, like
chr5_+_58564645 2.35 ENSDART00000045518
prkrip1
PRKR interacting protein 1 (IL11 inducible)
chr2_+_15379717 2.34 ENSDART00000058484
cnn3b
calponin 3, acidic b
chr25_+_17829003 2.33 ENSDART00000067305
zgc:103499
zgc:103499
chr8_+_19589519 2.31 ENSDART00000144667
slc35a3a
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3a
chr5_-_8206388 2.30 ENSDART00000062957
paip1
poly(A) binding protein interacting protein 1
chr23_-_24299965 2.30 ENSDART00000109134
plekhm2
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr17_+_23709676 2.30 ENSDART00000179026
zgc:91976
zgc:91976
chr5_+_52199767 2.28

chr20_+_52968725 2.28 ENSDART00000014606
phactr1
phosphatase and actin regulator 1
chr22_-_11799717 2.28 ENSDART00000126784
ptpn4b
protein tyrosine phosphatase, non-receptor type 4b
chr7_+_31155071 2.27 ENSDART00000138456
eif3jb
eukaryotic translation initiation factor 3, subunit Jb
chr19_+_29750506 2.26 ENSDART00000164432
ldlrap1a
low density lipoprotein receptor adaptor protein 1a
chr16_-_39317068 2.25 ENSDART00000133642
gpd1l
glycerol-3-phosphate dehydrogenase 1-like
chr20_+_44684340 2.25 ENSDART00000149775
atad2b
ATPase family, AAA domain containing 2B
chr17_-_12095843 2.24 ENSDART00000155545
ahctf1
AT hook containing transcription factor 1
chr2_-_47827141 2.24 ENSDART00000056882
cul3a
cullin 3a
chr19_+_24741351 2.23 ENSDART00000090081
sema4ab
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Ab
chr3_-_36940649 2.21 ENSDART00000110716
ENSDART00000160233
tubg1
tubulin, gamma 1
chr7_+_68964813 2.21 ENSDART00000166258
marveld3
MARVEL domain containing 3
chr17_+_34238753 2.20 ENSDART00000014306
mpp5a
membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5)
chr15_+_25503446 2.19 ENSDART00000154164
aifm4
apoptosis-inducing factor, mitochondrion-associated, 4
chr8_+_59148 2.18 ENSDART00000159739
ENSDART00000122378
cep120
centrosomal protein 120
chr19_-_46500888 2.15 ENSDART00000178772
ptdss1b
phosphatidylserine synthase 1b
chr10_+_16543577 2.14 ENSDART00000121864
slc27a6
solute carrier family 27 (fatty acid transporter), member 6
chr7_-_38443332 2.11 ENSDART00000047220
fbxo3
F-box protein 3
chr14_+_31189527 2.11 ENSDART00000053026
fam122b
family with sequence similarity 122B
chr17_-_43725091 2.11

chr24_-_6304289 2.10 ENSDART00000140212
zgc:174877
zgc:174877
chr10_+_21487458 2.10 ENSDART00000147215
ENSDART00000019252
fbxw11b
F-box and WD repeat domain containing 11b
chr5_+_36067010 2.09 ENSDART00000097686
zgc:153990
zgc:153990
chr15_-_24007488 2.06 ENSDART00000002824
appbp2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr22_-_7976467 2.05 ENSDART00000162028
sc:d217
sc:d217
chr21_+_7570420 2.04 ENSDART00000161921
zgc:113019
zgc:113019
chr3_+_13780104 2.04 ENSDART00000164179
syce2
synaptonemal complex central element protein 2
chr18_-_510340 2.02 ENSDART00000164374
si:ch211-79l17.1
si:ch211-79l17.1
chr12_+_47828020 1.99 ENSDART00000112010
lzts2b
leucine zipper, putative tumor suppressor 2b
chr13_-_3805904 1.97 ENSDART00000017052
ncoa4
nuclear receptor coactivator 4
chr4_-_10770022 1.97

chr25_-_13394261 1.97 ENSDART00000056721
ldhd
lactate dehydrogenase D
chr6_+_28001359 1.95 ENSDART00000139367
amotl2a
angiomotin like 2a
chr3_-_6833379 1.95 ENSDART00000123724
atg4db
autophagy related 4D, cysteine peptidase b
chr16_+_28857531 1.95 ENSDART00000161525
zgc:171704
zgc:171704
chr5_+_6005049 1.94

chr15_+_28477741 1.94 ENSDART00000057257
pitpnaa
phosphatidylinositol transfer protein, alpha a
chr19_+_16159980 1.94 ENSDART00000151169
gmeb1
glucocorticoid modulatory element binding protein 1
chr15_-_161052 1.93

chr15_-_23588004 1.92 ENSDART00000078396
hmbsb
hydroxymethylbilane synthase, b
chr22_-_28828300 1.92 ENSDART00000104880
si:dkeyp-34c12.1
si:dkeyp-34c12.1
chr17_-_51729568 1.91 ENSDART00000157244
exd2
exonuclease 3'-5' domain containing 2
chr19_-_24551474 1.91 ENSDART00000104087
thap7
THAP domain containing 7
chr9_-_35824470 1.90 ENSDART00000140356
zp2l1
zona pellucida glycoprotein 2, like 1
chr16_-_4940519 1.90 ENSDART00000149421
rpa2
replication protein A2
chr11_+_6872272 1.90 ENSDART00000075998
klhl26
kelch-like family member 26
chr14_+_15788442 1.88 ENSDART00000159181
immt
inner membrane protein, mitochondrial (mitofilin)
chr7_-_73625494 1.87 ENSDART00000041385
zgc:163061
zgc:163061
chr15_+_6462943 1.86 ENSDART00000065824
bace2
beta-site APP-cleaving enzyme 2
chr17_+_23463668 1.85

chr14_+_30434751 1.84 ENSDART00000139975
atl3
atlastin 3
chr9_-_18807868 1.83

chr11_-_12174576 1.82 ENSDART00000147670
npepps
aminopeptidase puromycin sensitive
chr21_-_21142020 1.81 ENSDART00000079678
ftsj1
FtsJ RNA methyltransferase homolog 1 (E. coli)
chr20_+_791476 1.80 ENSDART00000137135
mei4
meiosis-specific, MEI4 homolog (S. cerevisiae)
chr4_-_20456517 1.80 ENSDART00000003621
ENSDART00000132356
sinup
siaz-interacting nuclear protein
chr22_-_7887341 1.78 ENSDART00000097198
sc:d217
sc:d217
chr24_-_36412892 1.77 ENSDART00000148868
coasy
CoA synthase
chr19_-_25843075 1.77 ENSDART00000036854
glcci1
glucocorticoid induced 1
chr8_-_41511380 1.76 ENSDART00000019858
golga1
golgin A1
chr8_+_23360660 1.76 ENSDART00000142783
mapre1a
microtubule-associated protein, RP/EB family, member 1a
chr1_-_49307663 1.74

chr10_+_21487218 1.74 ENSDART00000147215
ENSDART00000019252
fbxw11b
F-box and WD repeat domain containing 11b
chr5_-_62389958 1.71

chr3_+_53097692 1.70 ENSDART00000082715
camsap3
calmodulin regulated spectrin-associated protein family, member 3
chr15_-_23587867 1.69 ENSDART00000078396
hmbsb
hydroxymethylbilane synthase, b
chr3_-_27470798 1.69 ENSDART00000077734
zgc:66160
zgc:66160
chr15_+_31709330 1.69 ENSDART00000159634
b3glcta
beta 3-glucosyltransferase a
chr15_-_24007354 1.68 ENSDART00000002824
appbp2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr2_+_31959127 1.67 ENSDART00000132113
otulinb
OTU deubiquitinase with linear linkage specificity b
chr5_-_68751287 1.67 ENSDART00000112692
ENSDARG00000077155
ENSDARG00000077155
chr8_-_14571436 1.67 ENSDART00000146175
cep350
centrosomal protein 350
chr5_+_4092360 1.66 ENSDART00000158826
CABZ01058650.1
ENSDARG00000101063
chr3_+_16880842 1.65 ENSDART00000080854
stat3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr2_+_35750334 1.64 ENSDART00000052666
rasal2
RAS protein activator like 2
chr10_-_25059072 1.64 ENSDART00000040733
cd209
CD209 molecule
chr7_-_73625414 1.63 ENSDART00000041385
zgc:163061
zgc:163061
chr17_-_12095723 1.63 ENSDART00000115321
ahctf1
AT hook containing transcription factor 1
chr19_-_12158958 1.63 ENSDART00000024193
rnf19a
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr25_-_13307171 1.63 ENSDART00000056723
gins3
GINS complex subunit 3
chr17_+_26785230 1.62 ENSDART00000023470
pgrmc2
progesterone receptor membrane component 2
chr7_+_58448909 1.62 ENSDART00000024185
zgc:56231
zgc:56231
chr3_-_45018353 1.62 ENSDART00000166146
dnajb1a
DnaJ (Hsp40) homolog, subfamily B, member 1a
chr16_-_11350199 1.62 ENSDART00000134752
znf526
zinc finger protein 526
chr17_-_22553428 1.62 ENSDART00000079390
exo1
exonuclease 1
chr24_-_5904097 1.60 ENSDART00000007373
ENSDART00000135124
acbd5a
acyl-CoA binding domain containing 5a
chr8_+_23126036 1.60 ENSDART00000141175
gid8a
GID complex subunit 8 homolog a (S. cerevisiae)
chr7_+_29930406 1.59 ENSDART00000075588
wdr76
WD repeat domain 76
chr19_-_35863647 1.59 ENSDART00000179357
anln
anillin, actin binding protein
chr18_+_1018614 1.57 ENSDART00000161206
pkma
pyruvate kinase, muscle, a
chr19_+_10640291 1.57 ENSDART00000151801
usf2
upstream transcription factor 2, c-fos interacting
chr3_+_45375580 1.56 ENSDART00000162799
crb3a
crumbs homolog 3a
chr1_-_44227583 1.55 ENSDART00000134635
si:dkey-9i23.15
si:dkey-9i23.15
chr1_-_39384698 1.54 ENSDART00000147317
cntf
ciliary neurotrophic factor
chr10_+_16544000 1.53 ENSDART00000121864
slc27a6
solute carrier family 27 (fatty acid transporter), member 6
chr8_-_49739908 1.53 ENSDART00000138810
gkap1
G kinase anchoring protein 1
chr8_-_31407839 1.52 ENSDART00000098912
znf131
zinc finger protein 131
chr6_-_6818607 1.51 ENSDART00000151822
tuba8l4
tubulin, alpha 8 like 4
chr21_-_40556480 1.51 ENSDART00000168850
taok1b
TAO kinase 1b
chr6_-_33886299 1.51 ENSDART00000115409
mast2
microtubule associated serine/threonine kinase 2
chr10_+_40405689 1.51

chr8_-_41511321 1.50 ENSDART00000019858
golga1
golgin A1
chr7_-_69114652 1.50

chr15_-_28636615 1.50 ENSDART00000127845
ssh2a
slingshot protein phosphatase 2a
chr16_-_41854586 1.49 ENSDART00000134718
psmc4
proteasome 26S subunit, ATPase 4
chr10_-_26240909 1.48 ENSDART00000131394
fhdc3
FH2 domain containing 3
chr17_+_13292569 1.46 ENSDART00000177104
BX005308.2
ENSDARG00000108498
chr25_-_13562558 1.46 ENSDART00000045488
csnk2a2b
casein kinase 2, alpha prime polypeptide b
chr6_+_19933322 1.45 ENSDART00000143378
thumpd3
THUMP domain containing 3
chr18_-_16927749 1.45 ENSDART00000100105
ENSDART00000163400
swap70b
SWAP switching B-cell complex 70b subunit 70b
chr22_-_6490288 1.45 ENSDART00000149676
CR352226.7
ENSDARG00000095952
chr11_-_25223594 1.45 ENSDART00000014945
hcfc1a
host cell factor C1a

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:0044320 leptin-mediated signaling pathway(GO:0033210) cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
1.2 7.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
1.0 4.1 GO:0051977 maintenance of blood-brain barrier(GO:0035633) lysophospholipid transport(GO:0051977) lipid transport across blood brain barrier(GO:1990379)
1.0 2.9 GO:0008356 asymmetric cell division(GO:0008356)
1.0 3.9 GO:0046931 pore complex assembly(GO:0046931) nuclear pore complex assembly(GO:0051292)
1.0 3.8 GO:0010482 keratinocyte development(GO:0003334) epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.9 4.4 GO:0015682 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.9 3.5 GO:0030728 ovulation(GO:0030728)
0.7 2.2 GO:0061511 centriole elongation(GO:0061511)
0.7 2.1 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.7 2.8 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.7 2.6 GO:0043243 positive regulation of protein complex disassembly(GO:0043243)
0.7 2.6 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.6 12.7 GO:0001840 neural plate development(GO:0001840)
0.6 6.0 GO:0097324 beta-amyloid metabolic process(GO:0050435) melanocyte migration(GO:0097324)
0.6 3.0 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.6 2.9 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.5 4.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.5 3.6 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.5 2.0 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.5 3.0 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.5 1.5 GO:0014015 positive regulation of gliogenesis(GO:0014015) positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.5 3.9 GO:1990108 protein linear deubiquitination(GO:1990108)
0.5 1.4 GO:0097704 response to oscillatory fluid shear stress(GO:0097702) cellular response to oscillatory fluid shear stress(GO:0097704)
0.4 2.2 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.4 2.6 GO:0021698 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698)
0.4 2.9 GO:0030242 pexophagy(GO:0030242)
0.4 1.2 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.4 0.8 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.4 1.6 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.4 1.9 GO:0000212 meiotic spindle organization(GO:0000212)
0.4 1.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.4 3.3 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.4 2.5 GO:0070987 error-free translesion synthesis(GO:0070987)
0.3 1.7 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.3 1.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.3 1.6 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.3 2.6 GO:0051013 microtubule severing(GO:0051013)
0.3 7.4 GO:0015908 fatty acid transport(GO:0015908)
0.3 0.6 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.3 2.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.3 1.8 GO:0061635 regulation of protein complex stability(GO:0061635)
0.3 1.2 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.3 4.6 GO:0034453 microtubule anchoring(GO:0034453)
0.3 2.0 GO:0035909 aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.3 4.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.3 6.0 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.3 1.1 GO:0031642 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.3 1.6 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.3 3.3 GO:0097320 membrane tubulation(GO:0097320)
0.2 1.9 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.2 1.6 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.2 3.2 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.2 1.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 1.8 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.2 1.3 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.2 1.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 0.9 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2 1.4 GO:0016578 histone deubiquitination(GO:0016578)
0.2 1.0 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 2.9 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.2 4.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.2 5.9 GO:0030488 tRNA methylation(GO:0030488)
0.2 1.7 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.2 1.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.2 1.0 GO:0031112 positive regulation of microtubule polymerization or depolymerization(GO:0031112)
0.2 5.1 GO:0015914 phospholipid transport(GO:0015914)
0.2 0.5 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.2 0.6 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.4 GO:0046080 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.1 2.7 GO:0006298 mismatch repair(GO:0006298)
0.1 2.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 1.9 GO:0043171 peptide catabolic process(GO:0043171)
0.1 1.0 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.1 0.4 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 2.0 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 0.5 GO:0044878 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.1 4.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 2.2 GO:0010632 regulation of epithelial cell migration(GO:0010632)
0.1 3.5 GO:0048263 determination of dorsal identity(GO:0048263)
0.1 1.8 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 0.7 GO:0003160 endocardium morphogenesis(GO:0003160)
0.1 0.4 GO:0090166 Golgi disassembly(GO:0090166)
0.1 3.9 GO:0001878 response to yeast(GO:0001878)
0.1 4.4 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 1.2 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 1.2 GO:0051646 mitochondrion localization(GO:0051646)
0.1 2.5 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1 2.1 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.1 4.2 GO:0051225 spindle assembly(GO:0051225)
0.1 4.9 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.1 1.5 GO:0097194 execution phase of apoptosis(GO:0097194)
0.1 1.6 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 1.2 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 3.1 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.1 1.2 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 4.6 GO:0007283 spermatogenesis(GO:0007283)
0.1 1.2 GO:0010212 response to ionizing radiation(GO:0010212)
0.1 3.5 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.1 1.6 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 1.7 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 0.9 GO:0033505 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.1 9.0 GO:0007018 microtubule-based movement(GO:0007018)
0.1 0.3 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.1 1.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 1.3 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.7 GO:0042407 cristae formation(GO:0042407)
0.0 0.2 GO:0030730 regulation of sequestering of triglyceride(GO:0010889) positive regulation of sequestering of triglyceride(GO:0010890) sequestering of triglyceride(GO:0030730)
0.0 1.1 GO:0035329 hippo signaling(GO:0035329)
0.0 4.5 GO:0006936 muscle contraction(GO:0006936)
0.0 1.0 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 3.6 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 1.3 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.7 GO:0030225 macrophage differentiation(GO:0030225)
0.0 1.5 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.0 1.6 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.5 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.2 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.6 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 1.8 GO:0072329 monocarboxylic acid catabolic process(GO:0072329)
0.0 1.6 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 1.7 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 0.7 GO:0002429 immune response-activating cell surface receptor signaling pathway(GO:0002429)
0.0 0.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 2.7 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.3 GO:0070663 regulation of mononuclear cell proliferation(GO:0032944) regulation of T cell proliferation(GO:0042129) regulation of lymphocyte proliferation(GO:0050670) regulation of leukocyte proliferation(GO:0070663)
0.0 0.6 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 2.9 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 2.5 GO:0006338 chromatin remodeling(GO:0006338)
0.0 1.3 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 1.6 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 8.0 GO:0045944 positive regulation of transcription from RNA polymerase II promoter(GO:0045944)
0.0 0.6 GO:0051402 neuron apoptotic process(GO:0051402)
0.0 0.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 1.0 GO:0006954 inflammatory response(GO:0006954)
0.0 1.6 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 1.3 GO:0008033 tRNA processing(GO:0008033)
0.0 1.5 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.9 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.6 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.8 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.5 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.0 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 1.1 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.5 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.2 GO:0000800 lateral element(GO:0000800)
1.5 7.6 GO:0035517 PR-DUB complex(GO:0035517)
1.1 3.3 GO:0000801 central element(GO:0000801)
1.1 3.2 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.5 2.6 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.5 2.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.4 1.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.4 3.9 GO:0071797 LUBAC complex(GO:0071797)
0.4 2.0 GO:0001917 photoreceptor inner segment(GO:0001917)
0.4 1.2 GO:0097361 CIA complex(GO:0097361)
0.4 2.4 GO:0070876 SOSS complex(GO:0070876)
0.4 2.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.4 2.9 GO:0005826 actomyosin contractile ring(GO:0005826)
0.4 2.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.4 2.1 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.3 3.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.3 1.6 GO:0000811 GINS complex(GO:0000811)
0.3 2.5 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.3 1.2 GO:0017054 negative cofactor 2 complex(GO:0017054)
0.3 0.9 GO:0019185 snRNA-activating protein complex(GO:0019185)
0.3 2.8 GO:0070652 HAUS complex(GO:0070652)
0.2 1.7 GO:0000938 GARP complex(GO:0000938)
0.2 1.2 GO:0001772 immunological synapse(GO:0001772)
0.2 1.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 1.9 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.2 4.1 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.2 1.0 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.2 1.7 GO:0036449 microtubule minus-end(GO:0036449)
0.2 3.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 9.0 GO:0005871 kinesin complex(GO:0005871)
0.1 1.9 GO:0061617 MICOS complex(GO:0061617)
0.1 4.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.3 GO:0030667 secretory granule membrane(GO:0030667)
0.1 1.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 5.0 GO:0030496 midbody(GO:0030496)
0.1 7.7 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 1.8 GO:1990752 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.1 7.8 GO:0005802 trans-Golgi network(GO:0005802)
0.1 1.4 GO:0005876 spindle microtubule(GO:0005876)
0.1 0.8 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.1 2.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 5.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 1.1 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.1 1.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 2.7 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 1.1 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.9 GO:0070822 Sin3-type complex(GO:0070822)
0.1 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.8 GO:0071564 npBAF complex(GO:0071564)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 2.2 GO:0005814 centriole(GO:0005814)
0.0 1.0 GO:0030286 dynein complex(GO:0030286)
0.0 0.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.5 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 2.4 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 5.2 GO:0005681 spliceosomal complex(GO:0005681)
0.0 4.1 GO:0005813 centrosome(GO:0005813)
0.0 0.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.6 GO:0005771 multivesicular body(GO:0005771)
0.0 3.4 GO:0005769 early endosome(GO:0005769)
0.0 2.4 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.7 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.6 GO:0016605 PML body(GO:0016605)
0.0 1.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.8 GO:0000785 chromatin(GO:0000785)
0.0 1.6 GO:0009986 cell surface(GO:0009986)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
1.6 6.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
1.4 4.2 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
1.1 7.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
1.0 4.1 GO:0051978 lysophospholipid transporter activity(GO:0051978)
0.9 2.8 GO:0030626 U12 snRNA binding(GO:0030626)
0.9 2.8 GO:0004753 saccharopine dehydrogenase activity(GO:0004753) saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity(GO:0047131)
0.9 4.4 GO:0004998 transferrin receptor activity(GO:0004998)
0.9 2.6 GO:0008384 IkappaB kinase activity(GO:0008384)
0.7 5.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.7 2.0 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.6 2.6 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.6 3.0 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.5 2.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.5 1.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.5 2.6 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.5 3.6 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.5 2.6 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.5 1.9 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.4 2.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.4 1.3 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.4 1.7 GO:0030507 spectrin binding(GO:0030507)
0.4 1.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.4 1.2 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.4 1.6 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.4 6.0 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.4 1.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.3 5.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.3 3.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.3 1.3 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.3 1.2 GO:0003823 antigen binding(GO:0003823) lipid antigen binding(GO:0030882)
0.3 1.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 1.0 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 0.9 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 2.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.2 4.2 GO:0008171 O-methyltransferase activity(GO:0008171)
0.2 2.3 GO:0008494 translation activator activity(GO:0008494)
0.2 0.6 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.2 1.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 4.9 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.2 2.3 GO:0019894 kinesin binding(GO:0019894)
0.2 9.0 GO:0003777 microtubule motor activity(GO:0003777)
0.2 1.2 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
0.1 0.4 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.1 1.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 2.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 4.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 3.3 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.1 1.0 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 1.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 2.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 1.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 4.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.3 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 8.0 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 2.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.4 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 1.2 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 2.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 7.4 GO:0019904 protein domain specific binding(GO:0019904)
0.1 1.2 GO:0031386 protein tag(GO:0031386)
0.1 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 3.1 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.1 2.6 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 4.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 6.0 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.5 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 2.7 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 2.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.2 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.5 GO:0005126 cytokine receptor binding(GO:0005126)
0.0 2.2 GO:0031625 ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.0 0.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 1.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 4.3 GO:0008017 microtubule binding(GO:0008017)
0.0 1.0 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 3.1 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 1.9 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.0 0.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 1.4 GO:0005262 calcium channel activity(GO:0005262)
0.0 4.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.5 GO:0044325 ion channel binding(GO:0044325)
0.0 0.4 GO:0022884 protein transmembrane transporter activity(GO:0008320) macromolecule transmembrane transporter activity(GO:0022884)
0.0 0.1 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 5.9 GO:0003924 GTPase activity(GO:0003924)
0.0 3.0 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 3.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.3 2.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 10.2 PID PLK1 PATHWAY PLK1 signaling events
0.2 4.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 5.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 5.4 PID BCR 5PATHWAY BCR signaling pathway
0.1 1.9 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 1.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 2.4 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.1 1.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 0.7 PID IL1 PATHWAY IL1-mediated signaling events
0.1 3.0 PID CMYB PATHWAY C-MYB transcription factor network
0.1 3.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.6 PID ATR PATHWAY ATR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.4 2.6 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.4 4.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.4 7.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.4 3.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.3 4.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.3 2.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 0.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2 3.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 3.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.9 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 2.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 5.2 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 1.4 REACTOME KINESINS Genes involved in Kinesins
0.1 1.0 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 3.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 4.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.2 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 1.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 1.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 2.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 3.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 4.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER