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Results for mybl2b
Z-value: 2.61
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Transcription factors associated with mybl2b
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| mybl2b | dr10_dc_chr11_+_1524965_1525123 | -0.56 | 2.4e-02 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of mybl2b
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr24_+_21495522 Show fit | 9.96 |
ENSDART00000105925
|
general transcription factor IIIA, b |
|
| chr4_-_20456825 Show fit | 8.20 |
ENSDART00000003621
ENSDART00000132356 |
siaz-interacting nuclear protein |
|
| chr7_+_17695173 Show fit | 7.91 |
ENSDART00000101601
|
cysteine three histidine 1 |
|
| chr24_-_9857510 Show fit | 7.02 |
ENSDART00000136274
|
si:ch211-146l10.7 |
|
| chr11_+_29299382 Show fit | 6.54 |
|
|
|
| chr22_-_28828375 Show fit | 6.45 |
ENSDART00000104880
ENSDART00000005112 |
si:dkeyp-34c12.1 |
|
| chr10_+_32107014 Show fit | 6.40 |
ENSDART00000137373
|
si:ch211-266i6.3 |
|
| chr7_+_58448953 Show fit | 5.96 |
ENSDART00000024185
|
zgc:56231 |
|
| chr10_-_26240772 Show fit | 5.87 |
ENSDART00000131394
|
FH2 domain containing 3 |
|
| chr5_-_66145078 Show fit | 5.20 |
ENSDART00000041441
|
stress-induced phosphoprotein 1 |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 12.7 | GO:0001840 | neural plate development(GO:0001840) |
| 0.1 | 9.0 | GO:0007018 | microtubule-based movement(GO:0007018) |
| 0.0 | 8.0 | GO:0045944 | positive regulation of transcription from RNA polymerase II promoter(GO:0045944) |
| 0.3 | 7.4 | GO:0015908 | fatty acid transport(GO:0015908) |
| 1.2 | 7.1 | GO:0042138 | meiotic DNA double-strand break formation(GO:0042138) |
| 0.6 | 6.0 | GO:0097324 | beta-amyloid metabolic process(GO:0050435) melanocyte migration(GO:0097324) |
| 0.3 | 6.0 | GO:0060236 | regulation of mitotic spindle organization(GO:0060236) |
| 2.0 | 5.9 | GO:0044320 | leptin-mediated signaling pathway(GO:0033210) cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321) |
| 0.2 | 5.9 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.2 | 5.1 | GO:0015914 | phospholipid transport(GO:0015914) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 9.0 | GO:0005871 | kinesin complex(GO:0005871) |
| 2.7 | 8.2 | GO:0000800 | lateral element(GO:0000800) |
| 0.1 | 7.8 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.1 | 7.7 | GO:0005923 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
| 1.5 | 7.6 | GO:0035517 | PR-DUB complex(GO:0035517) |
| 0.1 | 5.3 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 5.2 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.1 | 5.0 | GO:0030496 | midbody(GO:0030496) |
| 0.1 | 4.4 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.2 | 4.1 | GO:0016282 | eukaryotic 43S preinitiation complex(GO:0016282) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 9.0 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.1 | 8.0 | GO:0036459 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 1.1 | 7.4 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.1 | 7.4 | GO:0019904 | protein domain specific binding(GO:0019904) |
| 1.6 | 6.2 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.4 | 6.0 | GO:0070001 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.0 | 6.0 | GO:0019901 | protein kinase binding(GO:0019901) |
| 0.0 | 5.9 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.3 | 5.2 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.7 | 5.1 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 10.2 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.7 | 5.9 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.1 | 5.6 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.1 | 5.4 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.2 | 4.8 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.1 | 3.0 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.1 | 3.0 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.3 | 2.6 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.1 | 2.4 | ST T CELL SIGNAL TRANSDUCTION | T Cell Signal Transduction |
| 0.1 | 1.9 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 7.4 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.7 | 5.9 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.1 | 5.2 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
| 0.0 | 4.9 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.3 | 4.7 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.1 | 4.3 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.4 | 4.2 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.4 | 3.2 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.2 | 3.2 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.2 | 3.0 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |