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Results for myca+mych

Z-value: 1.28

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Transcription factors associated with myca+mych

Gene Symbol Gene ID Gene Info
myca
ENSDARG00000045695 MYC proto-oncogene, bHLH transcription factor a
mych
ENSDARG00000077473 myelocytomatosis oncogene homolog

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mycadr10_dc_chr24_+_10273081_10273133-0.775.1e-04Click!
mychdr10_dc_chr6_+_50452229_504522540.504.6e-02Click!

Activity profile of myca+mych motif

Sorted Z-values of myca+mych motif

Network of associatons between targets according to the STRING database.

First level regulatory network of myca+mych

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr18_+_14308032 4.40

chr9_-_12916555 3.89 ENSDART00000140691
si:ch211-167j6.3
si:ch211-167j6.3
chr25_+_17593164 3.83 ENSDART00000171965
galnt18a
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18a
chr25_+_17593080 3.56 ENSDART00000171965
galnt18a
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18a
chr12_+_13053552 3.26 ENSDART00000124799
si:ch211-103b1.2
si:ch211-103b1.2
chr10_+_22065599 2.94 ENSDART00000143461
npm1a
nucleophosmin 1a (nucleolar phosphoprotein B23, numatrin)
chr5_-_15971338 2.92 ENSDART00000110437
piwil2
piwi-like RNA-mediated gene silencing 2
chr21_-_2296253 2.90 ENSDART00000162867
zgc:66483
zgc:66483
chr22_-_28828375 2.88 ENSDART00000104880
ENSDART00000005112
si:dkeyp-34c12.1
si:dkeyp-34c12.1
chr15_-_17163526 2.64 ENSDART00000101724
mos
v-mos Moloney murine sarcoma viral oncogene homolog
chr5_-_31738565 2.49 ENSDART00000017956
dab2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr23_-_21607742 2.33 ENSDART00000139092
rcc2
regulator of chromosome condensation 2
chr22_+_15317622 2.29 ENSDART00000045682
rrp36
ribosomal RNA processing 36
chr17_+_15527923 2.21 ENSDART00000148443
marcksb
myristoylated alanine-rich protein kinase C substrate b
chr16_-_31834830 2.21

chr25_+_17593235 2.19 ENSDART00000171965
galnt18a
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18a
chr14_+_15845853 2.06 ENSDART00000160973
polr1a
polymerase (RNA) I polypeptide A
chr7_+_30355221 2.05 ENSDART00000173533
ENSDART00000052541
ccnb2
cyclin B2
chr4_-_14193396 2.03 ENSDART00000101812
ENSDART00000143804
pus7l
pseudouridylate synthase 7-like
chr18_+_14677042 2.02 ENSDART00000138995
vps9d1
VPS9 domain containing 1
chr22_+_17235696 1.91 ENSDART00000134798
tdrd5
tudor domain containing 5
chr19_-_24971920 1.89 ENSDART00000132660
polr3gla
polymerase (RNA) III (DNA directed) polypeptide G like a
chr13_-_15011369 1.89 ENSDART00000163132
rab11fip5a
RAB11 family interacting protein 5a (class I)
chr22_+_2237813 1.86

chr19_+_39689450 1.78

chr23_+_38335290 1.72 ENSDART00000177981
ENSDART00000178842
CABZ01070579.1
ENSDARG00000109193
chr13_-_44885278 1.71 ENSDART00000159021
khdrbs1a
KH domain containing, RNA binding, signal transduction associated 1a
chr8_+_25276000 1.67 ENSDART00000049793
gstm.1
glutathione S-transferase mu, tandem duplicate 1
KN150266v1_-_68652 1.63

chr24_+_34183462 1.62 ENSDART00000143995
zgc:92591
zgc:92591
chr21_-_30045531 1.62 ENSDART00000157307
ccnjl
cyclin J-like
chr25_+_21001126 1.58 ENSDART00000079012
rad52
RAD52 homolog, DNA repair protein
chr19_+_21209328 1.57 ENSDART00000142463
txnl4a
thioredoxin-like 4A
chr5_-_19619201 1.52 ENSDART00000026516
pxmp2
peroxisomal membrane protein 2
chr13_+_31271568 1.51 ENSDART00000019202
tdrd9
tudor domain containing 9
chr22_+_4734033 1.51 ENSDART00000158846
mibp
muscle-specific beta 1 integrin binding protein
chr16_-_31834774 1.51

chr10_-_14971401 1.50 ENSDART00000044756
ENSDART00000128579
smad2
SMAD family member 2
chr4_-_13025193 1.50 ENSDART00000177894
BX119963.3
ENSDARG00000106390
chr11_-_44859225 1.49 ENSDART00000163776
eif4a3
eukaryotic translation initiation factor 4A3
chr8_+_40126740 1.47

chr24_+_39631194 1.45 ENSDART00000013894
dcun1d3
defective in cullin neddylation 1 domain containing 3
chr5_-_19619115 1.44 ENSDART00000026516
pxmp2
peroxisomal membrane protein 2
chr21_-_31215463 1.43 ENSDART00000170507
crcp
calcitonin gene-related peptide-receptor component protein
chr10_-_14971565 1.42 ENSDART00000147653
smad2
SMAD family member 2
chr22_+_4733940 1.42 ENSDART00000158279
mibp
muscle-specific beta 1 integrin binding protein
chr18_-_11626694 1.41 ENSDART00000098565
CRACR2A
calcium release activated channel regulator 2A
chr20_+_38354928 1.41 ENSDART00000149160
ccl38.6
chemokine (C-C motif) ligand 38, duplicate 6
chr23_+_38228263 1.39 ENSDART00000137969
zgc:112994
zgc:112994
chr21_+_25031903 1.37

chr1_-_55072271 1.35 ENSDART00000142244
dnajb1b
DnaJ (Hsp40) homolog, subfamily B, member 1b
chr20_-_47994260 1.33 ENSDART00000166857
CABZ01059120.1
ENSDARG00000100162
chr23_+_30803887 1.33 ENSDART00000134141
asxl1
additional sex combs like transcriptional regulator 1
chr13_-_29571309 1.32 ENSDART00000139773
CT025909.1
ENSDARG00000093614
chr25_+_33118422 1.32

chr11_+_25058986 1.31 ENSDART00000122249
top1l
topoisomerase (DNA) I, like
chr13_-_2296283 1.29 ENSDART00000017148
gclc
glutamate-cysteine ligase, catalytic subunit
chr5_+_68036497 1.26 ENSDART00000017849
her7
hairy and enhancer of split related-7
chr1_+_47323244 1.26

chr8_-_44247277 1.25

chr23_+_30803518 1.24 ENSDART00000134141
asxl1
additional sex combs like transcriptional regulator 1
chr3_-_18655432 1.22 ENSDART00000034489
msrb1a
methionine sulfoxide reductase B1a
chr11_+_6012910 1.21 ENSDART00000161001
gtpbp3
GTP binding protein 3
chr8_-_38284748 1.21 ENSDART00000102233
pdlim2
PDZ and LIM domain 2 (mystique)
chr13_+_35799681 1.21 ENSDART00000046115
mfsd2aa
major facilitator superfamily domain containing 2aa
chr13_+_30441704 1.21 ENSDART00000010052
ppifa
peptidylprolyl isomerase Fa
chr1_+_40134345 1.19 ENSDART00000177517
CR387992.1
ENSDARG00000108790
chr10_+_43953171 1.18

chr24_+_34183557 1.18 ENSDART00000143995
zgc:92591
zgc:92591
chr5_-_27394361 1.17 ENSDART00000132740
ppp3cca
protein phosphatase 3, catalytic subunit, gamma isozyme, a
chr3_+_18657831 1.16 ENSDART00000055757
tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr10_-_39362315 1.15 ENSDART00000023831
cry5
cryptochrome circadian clock 5
chr3_+_41984648 1.14 ENSDART00000154052
ftsj2
FtsJ RNA methyltransferase homolog 2 (E. coli)
chr14_+_15845943 1.14 ENSDART00000159352
polr1a
polymerase (RNA) I polypeptide A
chr1_-_18955249 1.13 ENSDART00000146688
polr1e
polymerase (RNA) I polypeptide E
chr7_-_31346802 1.13 ENSDART00000111388
igdcc3
immunoglobulin superfamily, DCC subclass, member 3
chr11_-_13094557 1.13 ENSDART00000160989
elovl1b
ELOVL fatty acid elongase 1b
chr13_-_11888944 1.11 ENSDART00000125430
pprc1
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr21_+_6009129 1.10 ENSDART00000065858
fpgs
folylpolyglutamate synthase
chr1_-_29958364 1.10 ENSDART00000085454
dis3
DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
chr15_-_1519615 1.10 ENSDART00000129356
si:dkeyp-97b10.3
si:dkeyp-97b10.3
chr19_-_34529880 1.10 ENSDART00000158677
ENSDART00000112004
si:dkey-184p18.2
si:dkey-184p18.2
chr6_+_3556296 1.09 ENSDART00000041627
ssb
Sjogren syndrome antigen B (autoantigen La)
chr5_-_9577533 1.09 ENSDART00000036421
chek2
checkpoint kinase 2
chr13_-_25277861 1.09 ENSDART00000002741
itprip
inositol 1,4,5-trisphosphate receptor interacting protein
chr24_+_39630741 1.09 ENSDART00000132939
dcun1d3
defective in cullin neddylation 1 domain containing 3
chr24_+_36429525 1.07 ENSDART00000062722
pus3
pseudouridylate synthase 3
chr23_+_21608152 1.07

KN149704v1_-_17031 1.06

chr21_-_22085596 1.06 ENSDART00000101726
slc35f2
solute carrier family 35, member F2
chr1_-_39297624 1.05 ENSDART00000165373
cdk2ap2
cyclin-dependent kinase 2 associated protein 2
chr19_-_9020995 1.05 ENSDART00000043507
ciarta
circadian associated repressor of transcription a
chr2_+_44928188 1.05 ENSDART00000147292
ece2a
endothelin converting enzyme 2a
chr15_-_28852613 1.04 ENSDART00000152147
blmh
bleomycin hydrolase
chr9_-_27585644 1.04 ENSDART00000101401
tex30
testis expressed 30
chr9_-_904565 1.04 ENSDART00000144068
zgc:101851
zgc:101851
chr20_-_46079578 1.03 ENSDART00000153228
AL929237.3
ENSDARG00000096676
chr13_-_44885345 1.03 ENSDART00000074787
ENSDART00000125633
khdrbs1a
KH domain containing, RNA binding, signal transduction associated 1a
chr11_+_25058714 1.03 ENSDART00000065949
top1l
topoisomerase (DNA) I, like
chr17_+_22740348 1.02 ENSDART00000151999
ttc27
tetratricopeptide repeat domain 27
chr22_-_26971170 1.02 ENSDART00000162742
ENSDARG00000061256
ENSDARG00000061256
chr11_+_24562450 1.02 ENSDART00000082761
ENSDART00000131976
adipor1a
adiponectin receptor 1a
chr3_-_5157662 1.02 ENSDART00000169609
tefb
thyrotrophic embryonic factor b
chr21_+_21760105 1.02 ENSDART00000003518
neu3.2
sialidase 3 (membrane sialidase), tandem duplicate 2
chr18_+_8959686 1.00 ENSDART00000145226
si:ch211-233h19.2
si:ch211-233h19.2
chr5_-_12592887 1.00

chr20_-_25732204 1.00 ENSDART00000048164
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr8_+_10825036 1.00 ENSDART00000140717
brpf3b
bromodomain and PHD finger containing, 3b
chr25_+_18997440 1.00 ENSDART00000155569
si:dkeyp-19h3.8
si:dkeyp-19h3.8
chr8_-_38284959 0.99 ENSDART00000125920
pdlim2
PDZ and LIM domain 2 (mystique)
chr23_-_33396673 0.98

chr22_-_23252993 0.97 ENSDART00000105613
si:dkey-121a9.3
si:dkey-121a9.3
chr21_+_25032002 0.96

chr15_-_43954665 0.96 ENSDART00000041249
chordc1a
cysteine and histidine-rich domain (CHORD) containing 1a
chr16_+_17857553 0.96 ENSDART00000148878
them4
thioesterase superfamily member 4
chr3_-_40791555 0.96 ENSDART00000055201
foxk1
forkhead box K1
chr9_-_27581087 0.95 ENSDART00000135221
nepro
nucleolus and neural progenitor protein
chr3_+_50398735 0.95

chr8_-_38284904 0.94 ENSDART00000125920
pdlim2
PDZ and LIM domain 2 (mystique)
chr20_+_25726978 0.94 ENSDART00000164264
ppat
phosphoribosyl pyrophosphate amidotransferase
chr7_-_31346844 0.92 ENSDART00000111388
igdcc3
immunoglobulin superfamily, DCC subclass, member 3
chr9_+_42656327 0.92

chr12_-_33256599 0.92 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr12_+_33874289 0.92 ENSDART00000125745
sfxn2
sideroflexin 2
chr13_+_30441803 0.91 ENSDART00000144417
ppifa
peptidylprolyl isomerase Fa
chr16_+_41004372 0.91 ENSDART00000058587
gbp
glycogen synthase kinase binding protein
chr3_-_40790889 0.91

chr14_-_5100304 0.91 ENSDART00000168074
pcgf1
polycomb group ring finger 1
chr18_+_6498590 0.91 ENSDART00000162398
c2cd5
C2 calcium-dependent domain containing 5
chr23_+_38335341 0.91 ENSDART00000177981
ENSDART00000178842
CABZ01070579.1
ENSDARG00000109193
chr3_+_41984196 0.91 ENSDART00000154052
ftsj2
FtsJ RNA methyltransferase homolog 2 (E. coli)
chr19_-_22761674 0.90

chr5_+_60782855 0.90 ENSDART00000074073
alkbh4
alkB homolog 4, lysine demthylase
chr17_+_26785230 0.90 ENSDART00000023470
pgrmc2
progesterone receptor membrane component 2
chr4_-_3015097 0.90 ENSDART00000128934
ENSDART00000019518
aebp2
AE binding protein 2
chr20_-_33802082 0.88 ENSDART00000166573
rock2b
rho-associated, coiled-coil containing protein kinase 2b
chr3_-_40791490 0.87 ENSDART00000055201
foxk1
forkhead box K1
chr23_+_38313746 0.87 ENSDART00000129593
znf217
zinc finger protein 217
chr6_-_44164161 0.86 ENSDART00000035513
shq1
SHQ1, H/ACA ribonucleoprotein assembly factor
chr10_+_29883772 0.86 ENSDART00000100032
hyou1
hypoxia up-regulated 1
chr13_-_35781185 0.86

chr21_+_34085267 0.85 ENSDART00000024750
hmgb3b
high mobility group box 3b
chr24_+_32754013 0.85 ENSDART00000156638
si:ch211-282b22.1
si:ch211-282b22.1
chr5_-_27394324 0.85 ENSDART00000132740
ppp3cca
protein phosphatase 3, catalytic subunit, gamma isozyme, a
chr14_-_21779536 0.84

chr23_-_21608024 0.84 ENSDART00000134587
rcc2
regulator of chromosome condensation 2
chr1_-_39297686 0.83 ENSDART00000165373
cdk2ap2
cyclin-dependent kinase 2 associated protein 2
chr14_-_35932521 0.83 ENSDART00000158722
BX511223.1
ENSDARG00000101064
chr21_+_25031760 0.82

chr3_+_43361682 0.81 ENSDART00000168784
nsmce1
NSE1 homolog, SMC5-SMC6 complex component
chr1_+_47323043 0.81

chr23_-_21608362 0.81 ENSDART00000010647
rcc2
regulator of chromosome condensation 2
chr25_+_17593263 0.80 ENSDART00000171965
galnt18a
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18a
chr21_-_11235148 0.80 ENSDART00000122331
rtkn2b
rhotekin 2b
chr8_+_42910943 0.79 ENSDART00000021715
slc23a2
solute carrier family 23 (ascorbic acid transporter), member 2
chr23_+_38314255 0.78 ENSDART00000129593
znf217
zinc finger protein 217
chr12_-_28422582 0.78 ENSDART00000067762
MYO1D
myosin ID
chr17_-_31802796 0.76 ENSDART00000172519
abraxas2b
abraxas 2b, BRISC complex subunit
chr24_-_38304083 0.76 ENSDART00000109975
crp7
C-reactive protein 7
chr20_-_7079663 0.76 ENSDART00000040793
sirt5
sirtuin 5
chr21_-_30045669 0.76 ENSDART00000155188
ccnjl
cyclin J-like
chr21_+_21760059 0.75 ENSDART00000003518
neu3.2
sialidase 3 (membrane sialidase), tandem duplicate 2
chr15_+_17163165 0.75

chr22_-_28828300 0.75 ENSDART00000104880
si:dkeyp-34c12.1
si:dkeyp-34c12.1
chr13_-_11888896 0.75 ENSDART00000125430
pprc1
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr22_+_15317535 0.75 ENSDART00000045682
rrp36
ribosomal RNA processing 36
chr13_+_39151166 0.75 ENSDART00000113259
ENSDARG00000079055
ENSDARG00000079055
chr20_-_7079412 0.74 ENSDART00000040793
sirt5
sirtuin 5
chr4_+_14107347 0.74 ENSDART00000150748
CU469420.1
ENSDARG00000086259
chr14_+_41042379 0.74 ENSDART00000173335
bcorl1
BCL6 corepressor-like 1
chr3_+_41984701 0.73 ENSDART00000154052
ftsj2
FtsJ RNA methyltransferase homolog 2 (E. coli)
chr3_+_5125139 0.73 ENSDART00000161755
CU681842.1
ENSDARG00000102795
chr17_+_15528557 0.73

chr21_-_31215400 0.72 ENSDART00000121946
crcp
calcitonin gene-related peptide-receptor component protein
chr5_-_67315284 0.72 ENSDART00000131665
gtf3aa
general transcription factor IIIAa
chr7_-_55238300 0.72 ENSDART00000148514
aprt
adenine phosphoribosyltransferase
chr8_+_26413471 0.71 ENSDART00000172542
ENSDART00000078369
zgc:136971
zgc:136971
chr15_+_17162691 0.71

chr3_-_40791035 0.70 ENSDART00000055201
foxk1
forkhead box K1
chr9_+_27909662 0.70 ENSDART00000112415
lcmt2
leucine carboxyl methyltransferase 2
chr13_-_35781541 0.70 ENSDART00000147522
mycla
MYCL proto-oncogene, bHLH transcription factor a
chr8_+_26040518 0.69 ENSDART00000009178
impdh2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr23_-_38228511 0.69 ENSDART00000087112
pfdn4
prefoldin subunit 4
chr13_-_35766296 0.69 ENSDART00000162399
tacc3
transforming, acidic coiled-coil containing protein 3
chr16_-_13723778 0.69 ENSDART00000139102
dbpb
D site albumin promoter binding protein b
chr18_-_20618924 0.68 ENSDART00000090156
ENSDART00000151980
bcl2l13
BCL2-like 13 (apoptosis facilitator)
chr12_-_5153412 0.68 ENSDART00000160037
fra10ac1
FRA10A associated CGG repeat 1
chr11_-_44859336 0.68 ENSDART00000157615
eif4a3
eukaryotic translation initiation factor 4A3
chr21_+_21760026 0.68 ENSDART00000003518
neu3.2
sialidase 3 (membrane sialidase), tandem duplicate 2
chr22_+_17235538 0.67 ENSDART00000134798
tdrd5
tudor domain containing 5
KN150266v1_-_68620 0.67

chr18_+_5637539 0.67

chr13_-_35781256 0.67

chr9_-_21649644 0.67 ENSDART00000133469
zmym2
zinc finger, MYM-type 2
chr24_+_35297193 0.65 ENSDART00000075142
ENSDART00000158801
pcmtd1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr24_+_35296732 0.65 ENSDART00000172652
pcmtd1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr19_-_22762165 0.64 ENSDART00000169065
ENSDART00000080260
zgc:109744
zgc:109744
chr3_+_43361636 0.62 ENSDART00000161277
nsmce1
NSE1 homolog, SMC5-SMC6 complex component
chr9_-_27909272 0.62 ENSDART00000161068
gtf2e1
general transcription factor IIE, polypeptide 1, alpha
chr17_+_26785073 0.61 ENSDART00000023470
pgrmc2
progesterone receptor membrane component 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.8 2.5 GO:1905207 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.7 2.2 GO:2001284 epithelial cell morphogenesis involved in gastrulation(GO:0003381) BMP secretion(GO:0038055) positive regulation of BMP secretion(GO:1900144) regulation of BMP secretion(GO:2001284)
0.7 2.7 GO:0006407 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
0.7 3.3 GO:1901993 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.6 2.5 GO:0010566 regulation of ketone biosynthetic process(GO:0010566) protein demalonylation(GO:0036046) peptidyl-lysine demalonylation(GO:0036047) protein desuccinylation(GO:0036048) peptidyl-lysine desuccinylation(GO:0036049) protein deglutarylation(GO:0061698)
0.5 4.5 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.5 1.4 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.4 1.3 GO:0000493 box H/ACA snoRNP assembly(GO:0000493)
0.4 2.6 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via single-strand annealing(GO:0045002)
0.4 4.8 GO:0009303 rRNA transcription(GO:0009303)
0.4 1.7 GO:0051977 maintenance of blood-brain barrier(GO:0035633) lysophospholipid transport(GO:0051977) lipid transport across blood brain barrier(GO:1990379)
0.4 2.9 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.4 2.4 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.4 1.5 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.4 1.5 GO:0030728 ovulation(GO:0030728)
0.4 2.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.3 1.9 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.3 0.9 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.3 1.4 GO:0002548 monocyte chemotaxis(GO:0002548) response to interferon-gamma(GO:0034341) cellular response to interferon-gamma(GO:0071346)
0.3 1.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119) mRNA pseudouridine synthesis(GO:1990481)
0.3 1.1 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.2 1.0 GO:0044209 AMP salvage(GO:0044209)
0.2 0.8 GO:0015882 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.2 2.1 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.2 0.5 GO:0034475 U4 snRNA 3'-end processing(GO:0034475) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.2 1.0 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.2 1.0 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 2.5 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.2 2.3 GO:0006265 DNA topological change(GO:0006265)
0.1 1.0 GO:0016075 rRNA catabolic process(GO:0016075)
0.1 0.4 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.1 2.0 GO:0001522 pseudouridine synthesis(GO:0001522)
0.1 0.4 GO:0070126 mitochondrial translational termination(GO:0070126)
0.1 0.6 GO:0034367 macromolecular complex remodeling(GO:0034367)
0.1 0.6 GO:0015682 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.1 0.3 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.1 0.6 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.1 1.1 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 0.5 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.1 2.3 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.8 GO:0032185 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.1 0.6 GO:0021571 rhombomere 5 development(GO:0021571) rhombomere 6 development(GO:0021572)
0.1 3.1 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.1 0.8 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.9 GO:0070989 oxidative demethylation(GO:0070989)
0.1 1.9 GO:0006301 postreplication repair(GO:0006301)
0.1 4.4 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 2.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 2.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.3 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 2.2 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 0.6 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
0.1 1.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 1.9 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 0.9 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.9 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 1.3 GO:0001757 somite specification(GO:0001757)
0.1 0.4 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 3.0 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.1 1.1 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.1 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 1.6 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.8 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 10.4 GO:0006486 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 0.6 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.2 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 1.0 GO:0071482 cellular response to light stimulus(GO:0071482)
0.0 0.1 GO:0045226 renal water homeostasis(GO:0003091) renal water transport(GO:0003097) extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.5 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 1.0 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.3 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.8 GO:0051028 mRNA transport(GO:0051028)
0.0 1.0 GO:0051298 centrosome duplication(GO:0051298)
0.0 1.4 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 1.0 GO:0007623 circadian rhythm(GO:0007623)
0.0 0.2 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.4 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.0 0.8 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.1 GO:0070084 protein initiator methionine removal(GO:0070084)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 1.6 GO:0006865 amino acid transport(GO:0006865)
0.0 0.5 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.9 GO:0045055 regulated exocytosis(GO:0045055)
0.0 0.1 GO:0046112 nucleobase biosynthetic process(GO:0046112)
0.0 0.2 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.0 0.5 GO:0001878 response to yeast(GO:0001878)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.9 GO:0001755 neural crest cell migration(GO:0001755)
0.0 1.3 GO:0045087 innate immune response(GO:0045087)
0.0 0.7 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0033391 chromatoid body(GO:0033391)
0.6 2.9 GO:0071546 pi-body(GO:0071546)
0.5 2.6 GO:0035517 PR-DUB complex(GO:0035517)
0.5 1.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.4 1.9 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.3 2.4 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.3 4.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.3 4.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 1.6 GO:0005955 calcineurin complex(GO:0005955)
0.2 2.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 0.6 GO:1990429 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.2 1.7 GO:0070938 contractile ring(GO:0070938)
0.1 1.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 2.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 1.9 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 3.8 GO:0030686 90S preribosome(GO:0030686)
0.1 2.0 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.4 GO:0008537 proteasome activator complex(GO:0008537)
0.1 1.5 GO:0043186 P granule(GO:0043186)
0.1 5.5 GO:0032432 actin filament bundle(GO:0032432)
0.1 1.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.8 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 1.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.6 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 4.0 GO:0030496 midbody(GO:0030496)
0.1 1.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 4.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.4 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.1 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.6 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.9 GO:0035102 PRC1 complex(GO:0035102)
0.0 3.3 GO:0000786 nucleosome(GO:0000786)
0.0 0.4 GO:0015030 Cajal body(GO:0015030)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.5 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 10.4 GO:0000139 Golgi membrane(GO:0000139)
0.0 4.6 GO:0005730 nucleolus(GO:0005730)
0.0 0.8 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 3.3 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.5 GO:0016605 PML body(GO:0016605)
0.0 0.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.6 GO:0000922 spindle pole(GO:0000922)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0034584 piRNA binding(GO:0034584)
0.6 2.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.6 1.9 GO:0004357 glutamate-cysteine ligase activity(GO:0004357) glutamate binding(GO:0016595)
0.6 2.5 GO:0061697 protein-malonyllysine demalonylase activity(GO:0036054) protein-succinyllysine desuccinylase activity(GO:0036055) protein-glutaryllysine deglutarylase activity(GO:0061697)
0.6 2.9 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.4 1.7 GO:0051978 lysophospholipid transporter activity(GO:0051978)
0.4 1.2 GO:0004044 amidophosphoribosyltransferase activity(GO:0004044)
0.4 2.4 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.4 1.2 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.4 1.5 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326)
0.4 1.8 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.4 1.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.3 2.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.2 0.7 GO:0002054 nucleobase binding(GO:0002054)
0.2 1.6 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 3.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 2.9 GO:0070411 I-SMAD binding(GO:0070411)
0.2 0.8 GO:0008142 oxysterol binding(GO:0008142)
0.2 2.1 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.2 6.8 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.2 1.2 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.2 3.3 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.2 2.7 GO:0008143 poly(A) binding(GO:0008143)
0.1 2.5 GO:0097602 cullin family protein binding(GO:0097602)
0.1 2.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 3.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.4 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 1.9 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.6 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.6 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.1 0.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.3 GO:0004001 adenosine kinase activity(GO:0004001)
0.1 0.8 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 1.4 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.4 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1 2.1 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.8 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.1 1.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 4.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 2.1 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 0.5 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 3.7 GO:0003724 RNA helicase activity(GO:0003724)
0.1 0.9 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.6 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.4 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 1.1 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 1.1 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 1.1 GO:0071949 FAD binding(GO:0071949)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 4.3 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.5 GO:0031386 protein tag(GO:0031386)
0.0 1.0 GO:0032451 demethylase activity(GO:0032451)
0.0 2.2 GO:0005516 calmodulin binding(GO:0005516)
0.0 3.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.2 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 3.2 GO:0042393 histone binding(GO:0042393)
0.0 0.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.4 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 3.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 3.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 2.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.7 PID AURORA A PATHWAY Aurora A signaling
0.0 0.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 1.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 2.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 1.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 2.0 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 0.6 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 2.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 2.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 3.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 0.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 0.5 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.1 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 4.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 2.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 2.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.8 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 0.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism