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Results for myf6

Z-value: 1.74

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Transcription factors associated with myf6

Gene Symbol Gene ID Gene Info
ENSDARG00000029830 myogenic factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
myf6dr10_dc_chr4_+_21996784_21996805-0.721.5e-03Click!

Activity profile of myf6 motif

Sorted Z-values of myf6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of myf6

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_-_73890950 6.41 ENSDART00000164992
RNA binding protein with multiple splicing
chr7_-_73890817 4.56 ENSDART00000164992
RNA binding protein with multiple splicing
chr7_-_59284273 3.97 ENSDART00000008554
La ribonucleoprotein domain family, member 7
chr7_-_59284362 3.75 ENSDART00000101731
La ribonucleoprotein domain family, member 7
chr19_-_27093095 3.23

chr1_-_30299017 2.90

chr1_-_44892852 2.43 ENSDART00000160961
activating transcription factor 7 interacting protein
chr12_+_30673985 2.38 ENSDART00000160422
aldehyde dehydrogenase 18 family, member A1
chr6_+_135002 2.31 ENSDART00000097468
zinc finger, GATA-like protein 1
chr7_+_17848688 2.28 ENSDART00000055810
zRAB1B, member RAS oncogene family a
chr9_+_22846286 2.23 ENSDART00000101765
si:dkey-189g17.2
chr4_-_6443552 2.18 ENSDART00000136572
forkhead box P2
chr2_+_28199458 2.18 ENSDART00000150330
bucky ball
chr1_-_44892600 2.15 ENSDART00000149155
activating transcription factor 7 interacting protein
chr23_+_46000362 2.14 ENSDART00000023944
lamin L3
chr23_-_6831711 2.12 ENSDART00000125393
ENSDARG00000089210
chr14_-_7102535 2.08 ENSDART00000036463
DND microRNA-mediated repression inhibitor 1
chr20_-_9212139 2.07 ENSDART00000064140
YLP motif containing 1
chr21_-_38670059 2.05 ENSDART00000065169
ENSDART00000113813
seven in absentia homolog 2 (Drosophila)-like
chr2_-_39761055 1.99 ENSDART00000179646
splA/ryanodine receptor domain and SOCS box containing 4a
chr12_-_10474942 1.92 ENSDART00000106163
ENSDART00000124562
zgc:152977
chr9_-_32240567 1.90

chr17_+_699708 1.89 ENSDART00000165144
SIVA1, apoptosis-inducing factor
KN150455v1_-_14200 1.86

chr20_-_14885629 1.85 ENSDART00000160481
SUN domain containing ossification factor
chr1_-_39622531 1.84

chr12_-_24711074 1.74 ENSDART00000066317
forkhead box N2b
chr2_-_54224744 1.72

chr4_-_6443699 1.69

chr19_+_14592632 1.69 ENSDART00000161088
ENSDART00000161965
zinc finger, DHHC-type containing 18b
chr13_+_11418060 1.67 ENSDART00000166908
desumoylating isopeptidase 2
chr13_-_50299643 1.61 ENSDART00000170527
ventral expressed homeobox
chr23_+_43868027 1.59 ENSDART00000112598
ENSDART00000169576
OTU deubiquitinase 4
KN150589v1_-_5209 1.58 ENSDART00000157761
ENSDART00000157531
ELOVL fatty acid elongase 7b
chr1_+_21964075 1.58 ENSDART00000161874
annexin A5b
chr25_-_34648876 1.53 ENSDART00000154851
zgc:153405
chr20_-_14885599 1.53 ENSDART00000160481
SUN domain containing ossification factor
chr7_+_45747622 1.50 ENSDART00000163991
cyclin E1
chr16_+_53391776 1.49 ENSDART00000010792
phosphatidylserine synthase 1a
chr7_-_41446221 1.48 ENSDART00000099121
ADP-ribosylation factor-like 8
chr2_-_45810787 1.48 ENSDART00000135665
pre-mRNA processing factor 38B
chr1_-_53052062 1.47 ENSDART00000162751
exportin 1 (CRM1 homolog, yeast) a
chr17_-_51729707 1.46 ENSDART00000157244
exonuclease 3'-5' domain containing 2
chr17_-_51729568 1.45 ENSDART00000157244
exonuclease 3'-5' domain containing 2
chr11_+_30005768 1.43 ENSDART00000167618
ENSDARG00000100936
chr16_+_53391438 1.43 ENSDART00000010792
phosphatidylserine synthase 1a
chr17_+_19606608 1.43 ENSDART00000044993
ENSDART00000131863
regulator of G protein signaling 7a
chr5_+_37144525 1.42 ENSDART00000148766
D4, zinc and double PHD fingers family 2
chr8_-_20106132 1.42 ENSDART00000029939
regulatory factor X, 2 (influences HLA class II expression)
chr17_+_15527923 1.42 ENSDART00000148443
myristoylated alanine-rich protein kinase C substrate b
chr25_-_352985 1.41 ENSDART00000165705
sizzled
chr3_-_31747486 1.41 ENSDART00000076189
zgc:171779
chr7_-_73890600 1.41 ENSDART00000164992
RNA binding protein with multiple splicing
chr9_+_38832959 1.40 ENSDART00000110651
solute carrier family 12, member 8
chr5_+_37144384 1.39 ENSDART00000148766
D4, zinc and double PHD fingers family 2
chr9_+_22846082 1.38 ENSDART00000139270
si:dkey-189g17.2
chr7_-_59284632 1.37 ENSDART00000101731
La ribonucleoprotein domain family, member 7
chr5_-_41260390 1.35 ENSDART00000140154
si:dkey-65b12.12
chr7_-_49528331 1.35 ENSDART00000052083
four jointed box 1
chr8_+_25126238 1.35 ENSDART00000136505
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr8_+_28362546 1.35 ENSDART00000062682
adiponectin receptor 1b
chr2_-_58805035 1.34 ENSDART00000159735
MAU2 sister chromatid cohesion factor
chr25_-_20932941 1.34 ENSDART00000138985
ENSDART00000046298
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr16_+_25202230 1.33 ENSDART00000163244
si:ch211-261d7.6
chr18_+_37279099 1.32 ENSDART00000135444
tubulin folding cofactor B
chr9_+_22846432 1.32 ENSDART00000101765
si:dkey-189g17.2
chr24_-_19574666 1.32 ENSDART00000135405
cysteine-serine-rich nuclear protein 1b
chr1_-_51075777 1.32 ENSDART00000152745
small nuclear ribonucleoprotein polypeptide B2
chr1_-_55072271 1.31 ENSDART00000142244
DnaJ (Hsp40) homolog, subfamily B, member 1b
chr8_+_40463218 1.31

chr9_-_18808049 1.31

chr6_-_39315705 1.29 ENSDART00000012644
keratin 4
chr21_+_22598805 1.28 ENSDART00000142495
ENSDARG00000089088
chr1_+_41762057 1.27 ENSDART00000137609
catenin (cadherin-associated protein), alpha 2
chr12_-_24711169 1.26 ENSDART00000066317
forkhead box N2b
chr20_-_3301951 1.25 ENSDART00000123096
myristoylated alanine-rich protein kinase C substrate a
chr17_+_28653205 1.24 ENSDART00000129779
HECT domain containing 1
chr13_+_11417882 1.24 ENSDART00000034935
desumoylating isopeptidase 2
chr7_+_51520610 1.23 ENSDART00000174201
solute carrier family 38, member 7
chr10_+_17919692 1.22

chr20_-_38884093 1.21 ENSDART00000153430
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a
chr17_-_6443618 1.21 ENSDART00000129950
ENSDART00000154074
si:ch211-189e2.2
chr24_-_42053682 1.20 ENSDART00000169725
zinc finger and BTB domain containing 14
chr15_+_14656797 1.19 ENSDART00000162350
F-box protein 46
chr12_-_25058837 1.19 ENSDART00000135368
ras homolog family member Q
chr2_+_35134340 1.16 ENSDART00000113609
ring finger and WD repeat domain 2
chr2_+_6341404 1.15 ENSDART00000076700
zona pellucida glycoprotein 3b
chr17_+_6310117 1.15 ENSDART00000149527
coenzyme Q8A
chr25_-_20933145 1.15 ENSDART00000138985
ENSDART00000046298
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
KN150455v1_-_14097 1.13

chr9_-_29218911 1.12 ENSDART00000151941
protein tyrosine phosphatase, non-receptor type 4a
chr3_-_15529158 1.11 ENSDART00000080441
zgc:66443
chr9_+_46748457 1.08

chr5_-_35997198 1.08 ENSDART00000031270
ras homolog gene family, member Gc
chr2_+_52225622 1.07 ENSDART00000170353
ENSDARG00000103108
chr7_-_20330881 1.06 ENSDART00000169750
si:dkey-19b23.11
KN150266v1_-_68652 1.06

chr16_-_40633986 1.06 ENSDART00000170815
ENSDARG00000100586
chr2_-_31849916 1.06 ENSDART00000109460
nucleolar protein 7
chr24_-_23793117 1.05

chr24_+_5771253 1.04 ENSDART00000154930
si:ch211-157j23.2
chr6_-_3763783 1.04 ENSDART00000170584
tousled-like kinase 1b
chr7_-_41446119 1.03 ENSDART00000099121
ADP-ribosylation factor-like 8
chr18_+_45669615 1.02 ENSDART00000150973
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr20_-_3301898 1.02 ENSDART00000123096
myristoylated alanine-rich protein kinase C substrate a
chr19_+_41895061 1.02 ENSDART00000087187
argonaute RISC catalytic component 2
chr7_+_24223131 1.01 ENSDART00000087568
negative elongation factor complex member A
chr13_-_50299821 1.01 ENSDART00000170527
ventral expressed homeobox
chr6_-_49160475 1.01 ENSDART00000041942
tetraspanin 2a
chr9_-_18807868 1.00

chr5_-_45219194 1.00

chr23_-_22596648 1.00 ENSDART00000079019
splA/ryanodine receptor domain and SOCS box containing 1
chr24_-_20496410 1.00 ENSDART00000166135
zinc finger and BTB domain containing 47b
chr20_-_26516874 0.99

chr24_-_19573966 0.99 ENSDART00000158952
ENSDART00000109107
ENSDART00000056082
cysteine-serine-rich nuclear protein 1b
chr7_+_34523283 0.98 ENSDART00000009698
epithelial splicing regulatory protein 2
chr20_+_35182783 0.98 ENSDART00000040456
CDC42 binding protein kinase alpha (DMPK-like) b
chr4_+_13413303 0.97 ENSDART00000003694
cullin-associated and neddylation-dissociated 1
chr7_-_50974318 0.97 ENSDART00000174297
ENSDARG00000105693
chr8_+_13327234 0.97 ENSDART00000159760
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr15_+_23421623 0.96 ENSDART00000113279
ring finger protein 26
chr17_+_5776013 0.96 ENSDART00000168326
zinc finger protein 513b
chr20_+_7337986 0.96 ENSDART00000140222
desmoglein 2, tandem duplicate 1
chr1_-_51863300 0.96 ENSDART00000004233
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr12_+_27444732 0.95 ENSDART00000013033
ets variant 4
chr20_-_14885722 0.95 ENSDART00000160481
SUN domain containing ossification factor
chr7_+_34235297 0.94 ENSDART00000173957
regulatory factor X, 7
chr8_+_29885318 0.94 ENSDART00000154309
ENSDARG00000097806
chr8_-_22265875 0.94 ENSDART00000134033
si:ch211-147a11.3
chr23_+_26153043 0.94 ENSDART00000054013
ATPase, H+ transporting, lysosomal accessory protein 1b
chr1_+_45907424 0.94 ENSDART00000053240
calcium binding protein 39-like
chr19_+_30212276 0.94

chr21_+_33216466 0.93 ENSDART00000163808
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1b
chr5_-_56641212 0.93 ENSDART00000050957
fer (fps/fes related) tyrosine kinase
chr3_-_42948612 0.92

chr16_+_36814839 0.91

chr11_-_44756789 0.91 ENSDART00000161712
synaptogyrin 2b
chr15_+_5125138 0.91 ENSDART00000101937
phosphoglucomutase 2-like 1
chr16_-_12362566 0.91 ENSDART00000116542
U7 small nuclear RNA
chr7_-_59284425 0.91 ENSDART00000101731
La ribonucleoprotein domain family, member 7
chr2_-_45810714 0.91 ENSDART00000135665
pre-mRNA processing factor 38B
chr8_-_22266041 0.91 ENSDART00000134033
si:ch211-147a11.3
chr7_-_54407355 0.90 ENSDART00000162795
cyclin D1
chr5_-_35997345 0.90 ENSDART00000122098
ras homolog gene family, member Gc
chr19_+_17899173 0.89 ENSDART00000123519
ubiquitin-conjugating enzyme E2E 1
chr21_+_10692781 0.89

chr16_-_2642235 0.89

chr22_-_680961 0.89 ENSDART00000149320
ADP-ribosylation factor-like 8A
chr6_+_9735100 0.89 ENSDART00000171518
abl-interactor 2b
chr11_+_44916426 0.89

chr15_+_6462447 0.88 ENSDART00000065824
beta-site APP-cleaving enzyme 2
chr12_+_5067663 0.87 ENSDART00000166600
centrosomal protein 55 like
chr20_-_9212089 0.87 ENSDART00000064140
YLP motif containing 1
chr5_+_61389881 0.87 ENSDART00000141574
si:dkey-35m8.1
chr17_-_6443673 0.87 ENSDART00000129950
ENSDART00000154074
si:ch211-189e2.2
chr13_-_37530793 0.87 ENSDART00000141295
si:dkey-188i13.11
chr3_-_42948574 0.87

chr16_+_25097165 0.86 ENSDART00000157312
zinc finger protein 1035
chr17_+_15527525 0.86 ENSDART00000159426
myristoylated alanine-rich protein kinase C substrate b
chr6_+_135255 0.86 ENSDART00000097468
zinc finger, GATA-like protein 1
chr7_+_56076854 0.86

chr12_+_9811557 0.86 ENSDART00000110458
family with sequence similarity 117, member Ab
chr14_+_20941526 0.86 ENSDART00000138551
small integral membrane protein 19
chr21_+_33216675 0.85 ENSDART00000163808
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1b
chr19_+_30212200 0.85

chr5_+_19363942 0.85 ENSDART00000051614
trichoplein, keratin filament binding
chr15_-_161052 0.85

chr15_+_14656886 0.85 ENSDART00000162350
F-box protein 46
chr20_-_3220475 0.84 ENSDART00000123331
serine peptidase inhibitor, Kunitz type 1 b
chr5_+_37496875 0.84 ENSDART00000135428
si:ch211-284e13.5
chr24_+_12845339 0.84 ENSDART00000126842
hypothetical protein FLJ11011-like (H. sapiens)
chr1_-_44892558 0.84 ENSDART00000149155
activating transcription factor 7 interacting protein
chr10_-_17214368 0.84

chr7_+_73598715 0.84 ENSDART00000109720
zgc:163061
chr4_+_4825461 0.83 ENSDART00000150309
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr7_-_73890499 0.83 ENSDART00000164992
RNA binding protein with multiple splicing
chr24_-_19574944 0.83 ENSDART00000135405
cysteine-serine-rich nuclear protein 1b
chr25_+_17593164 0.83 ENSDART00000171965
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18a
chr7_-_73620443 0.83 ENSDART00000158891
ENSDART00000111622
ENSDARG00000079652
chr17_+_30476515 0.82

chr19_+_42661987 0.82 ENSDART00000102698
jumping translocation breakpoint
chr23_-_27579257 0.82 ENSDART00000137229
ankyrin repeat and SOCS box containing 8
chr25_-_20933295 0.82 ENSDART00000138985
ENSDART00000046298
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr25_-_34599241 0.81 ENSDART00000156727
si:dkey-108k21.21
chr10_-_44634139 0.81 ENSDART00000010056
ENSDART00000169919
coiled-coil domain containing 62
chr11_+_2527564 0.81 ENSDART00000175330
DnaJ (Hsp40) homolog, subfamily C, member 14
chr10_-_6453139 0.81 ENSDART00000168549
carbonic anhydrase IX
chr8_-_22266750 0.81 ENSDART00000100042
ENSDART00000138966
si:ch211-147a11.3
chr17_+_28657998 0.81 ENSDART00000159067
HECT domain containing 1
chr7_-_69883542 0.80

chr19_+_30212565 0.80

chr6_-_3763940 0.80 ENSDART00000171804
tousled-like kinase 1b
chr9_+_188559 0.80 ENSDART00000162764
ribosomal RNA processing 1
chr24_-_20496308 0.80 ENSDART00000166135
zinc finger and BTB domain containing 47b
chr18_-_26995562 0.80 ENSDART00000147823
reticulocalbin 2
chr15_-_33669618 0.79 ENSDART00000161151
StAR-related lipid transfer (START) domain containing 13b
chr3_-_42949189 0.79 ENSDART00000161127
axin 1
chr11_+_11136919 0.79 ENSDART00000026135
lymphocyte antigen 75
chr19_+_30212487 0.79

chr10_-_44634167 0.79 ENSDART00000010056
ENSDART00000169919
coiled-coil domain containing 62

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 10.0 GO:1990437 snRNA 2'-O-methylation(GO:1990437) U6 2'-O-snRNA methylation(GO:1990438)
1.0 3.0 GO:1900144 epithelial cell morphogenesis involved in gastrulation(GO:0003381) BMP secretion(GO:0038055) positive regulation of BMP secretion(GO:1900144) regulation of BMP secretion(GO:2001284)
0.7 2.2 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.7 2.0 GO:0050957 equilibrioception(GO:0050957)
0.6 2.9 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.6 2.8 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.6 1.7 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.5 4.3 GO:0046850 regulation of bone remodeling(GO:0046850)
0.5 6.1 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.5 2.0 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.5 1.9 GO:1903449 male sex determination(GO:0030238) androst-4-ene-3,17-dione biosynthetic process(GO:1903449)
0.5 1.8 GO:0048103 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
0.5 3.6 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.5 1.4 GO:0044706 adult heart development(GO:0007512) female pregnancy(GO:0007565) embryo implantation(GO:0007566) multi-multicellular organism process(GO:0044706) apelin receptor signaling pathway(GO:0060183) trophoblast cell migration(GO:0061450) regulation of trophoblast cell migration(GO:1901163) positive regulation of trophoblast cell migration(GO:1901165)
0.4 2.9 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.4 2.1 GO:0060967 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.4 1.6 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.4 2.4 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.4 1.1 GO:0039535 negative regulation of type I interferon production(GO:0032480) cytoplasmic pattern recognition receptor signaling pathway in response to virus(GO:0039528) RIG-I signaling pathway(GO:0039529) regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531) regulation of RIG-I signaling pathway(GO:0039535) cellular response to virus(GO:0098586)
0.4 1.8 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.3 1.0 GO:0010265 SCF complex assembly(GO:0010265)
0.3 1.3 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.3 0.9 GO:0098751 bone cell development(GO:0098751)
0.3 3.7 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.3 3.5 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.3 3.0 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.3 2.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.3 1.3 GO:0098921 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.2 0.7 GO:0009098 leucine biosynthetic process(GO:0009098)
0.2 1.0 GO:0008057 eye pigment granule organization(GO:0008057)
0.2 0.7 GO:0042730 fibrinolysis(GO:0042730)
0.2 0.6 GO:0021846 cell proliferation in forebrain(GO:0021846) centriole elongation(GO:0061511)
0.2 0.7 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.2 0.7 GO:0043243 positive regulation of protein complex disassembly(GO:0043243)
0.2 1.1 GO:0050819 negative regulation of coagulation(GO:0050819)
0.2 0.7 GO:0002931 response to ischemia(GO:0002931)
0.2 0.7 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.2 0.5 GO:0030327 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.2 2.2 GO:0045471 response to ethanol(GO:0045471)
0.2 3.0 GO:0039014 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014)
0.2 0.5 GO:0035552 oxidative RNA demethylation(GO:0035513) oxidative single-stranded DNA demethylation(GO:0035552)
0.2 0.5 GO:0010259 multicellular organism aging(GO:0010259)
0.2 0.5 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037)
0.2 0.8 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 0.5 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.2 4.5 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.7 GO:0097009 energy homeostasis(GO:0097009)
0.1 1.0 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.1 0.6 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448) neurotransmitter catabolic process(GO:0042135)
0.1 5.6 GO:0048599 oocyte development(GO:0048599)
0.1 1.9 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 2.7 GO:0043652 engulfment of apoptotic cell(GO:0043652) regulation of neutrophil migration(GO:1902622)
0.1 0.4 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.1 1.5 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 0.5 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.6 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.1 0.7 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 0.3 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.1 0.4 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.1 3.5 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.4 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 1.0 GO:0097324 beta-amyloid metabolic process(GO:0050435) melanocyte migration(GO:0097324)
0.1 1.1 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.3 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.1 1.7 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 1.0 GO:0001709 cell fate determination(GO:0001709)
0.1 0.4 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 0.5 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.1 0.4 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 0.3 GO:0051204 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.1 0.4 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.1 10.5 GO:0030218 erythrocyte differentiation(GO:0030218) erythrocyte homeostasis(GO:0034101)
0.1 2.8 GO:0050821 protein stabilization(GO:0050821)
0.1 1.4 GO:0060046 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.2 GO:0006531 aspartate metabolic process(GO:0006531)
0.1 0.9 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 0.6 GO:0034389 lipid particle organization(GO:0034389)
0.1 1.9 GO:0006998 nuclear envelope organization(GO:0006998)
0.1 0.6 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.2 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.1 0.8 GO:0061709 reticulophagy(GO:0061709)
0.1 0.2 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 0.7 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.4 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.2 GO:0043393 regulation of protein binding(GO:0043393)
0.1 2.0 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 0.5 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.1 3.5 GO:0030901 midbrain development(GO:0030901)
0.1 2.0 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.1 0.1 GO:0048211 Golgi vesicle docking(GO:0048211)
0.1 0.2 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.3 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 0.2 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.1 0.2 GO:0071887 leukocyte apoptotic process(GO:0071887) regulation of leukocyte apoptotic process(GO:2000106)
0.1 1.4 GO:0051014 actin filament severing(GO:0051014)
0.1 2.1 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 1.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 2.8 GO:0006334 nucleosome assembly(GO:0006334)
0.1 1.6 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.3 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.3 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.6 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 1.2 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.0 0.1 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.0 0.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.7 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 2.2 GO:0097191 extrinsic apoptotic signaling pathway(GO:0097191)
0.0 1.1 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 3.7 GO:0006006 glucose metabolic process(GO:0006006)
0.0 1.0 GO:0043588 skin development(GO:0043588)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.4 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 4.2 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.7 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.6 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 2.8 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 1.2 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0 0.9 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.0 1.3 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 1.4 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.0 0.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.4 GO:0051222 positive regulation of protein transport(GO:0051222) positive regulation of establishment of protein localization(GO:1904951)
0.0 1.3 GO:0098661 inorganic anion transmembrane transport(GO:0098661)
0.0 0.5 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 1.4 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 1.4 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 1.7 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.3 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.3 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 1.6 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.0 1.6 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.4 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.1 GO:0003190 heart valve formation(GO:0003188) atrioventricular valve formation(GO:0003190)
0.0 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.3 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.3 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.7 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.4 GO:0003313 heart rudiment development(GO:0003313)
0.0 0.2 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.2 GO:0018200 peptidyl-glutamic acid modification(GO:0018200)
0.0 0.2 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.0 0.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048) amino sugar biosynthetic process(GO:0046349)
0.0 0.2 GO:0000459 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0 0.7 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.1 GO:0006404 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.0 0.2 GO:0090660 cerebrospinal fluid circulation(GO:0090660)
0.0 0.5 GO:0015908 fatty acid transport(GO:0015908)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 0.1 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 1.2 GO:0008544 epidermis development(GO:0008544)
0.0 0.6 GO:0060872 semicircular canal development(GO:0060872)
0.0 1.4 GO:0007188 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger(GO:0007187) adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 1.4 GO:0006913 nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169)
0.0 0.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 4.0 GO:0000398 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.1 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 2.1 GO:0006364 rRNA processing(GO:0006364)
0.0 0.3 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.7 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 0.1 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 0.2 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 0.2 GO:0007379 somite specification(GO:0001757) segment specification(GO:0007379)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0032019 mitochondrial cloud(GO:0032019)
0.5 5.2 GO:0045171 intercellular bridge(GO:0045171)
0.3 1.3 GO:0031251 PAN complex(GO:0031251)
0.3 1.0 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.3 1.5 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.2 2.8 GO:0005845 mRNA cap binding complex(GO:0005845)
0.2 1.6 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.2 0.6 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.2 1.9 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.2 1.5 GO:0032021 NELF complex(GO:0032021)
0.2 0.7 GO:1902636 kinociliary basal body(GO:1902636)
0.2 0.5 GO:0034709 methylosome(GO:0034709)
0.1 0.4 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 0.7 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 1.7 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 1.0 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 2.7 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 8.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 5.0 GO:0032432 actin filament bundle(GO:0032432)
0.1 0.6 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 1.3 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 2.6 GO:0071565 nBAF complex(GO:0071565)
0.1 1.7 GO:0043186 P granule(GO:0043186)
0.1 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.5 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.4 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 1.4 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 0.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.3 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 0.4 GO:0016589 NURF complex(GO:0016589)
0.1 2.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 2.3 GO:0030496 midbody(GO:0030496)
0.1 5.3 GO:0000786 nucleosome(GO:0000786)
0.0 4.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.9 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.5 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.6 GO:0044545 NSL complex(GO:0044545)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 1.0 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.2 GO:0030880 RNA polymerase complex(GO:0030880)
0.0 3.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 2.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase II, core complex(GO:0005665) DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.4 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.3 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 1.1 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 8.4 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.9 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:0097546 ciliary base(GO:0097546)
0.0 0.1 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 15.6 GO:0005654 nucleoplasm(GO:0005654)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.0 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0042641 actomyosin(GO:0042641)
0.0 0.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.7 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.4 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.6 GO:0005814 centriole(GO:0005814)
0.0 0.5 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.2 GO:0045095 keratin filament(GO:0045095)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 10.0 GO:0097322 7SK snRNA binding(GO:0097322)
0.6 2.8 GO:0070551 endoribonuclease activity, cleaving siRNA-paired mRNA(GO:0070551)
0.5 1.9 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.4 1.2 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.4 1.5 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.4 2.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.3 0.9 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.3 2.8 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.3 1.9 GO:0043495 protein anchor(GO:0043495)
0.3 0.8 GO:0004617 phosphoglycerate dehydrogenase activity(GO:0004617)
0.2 0.7 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 1.0 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.2 1.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2 1.4 GO:0031704 apelin receptor binding(GO:0031704)
0.2 1.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.2 2.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 2.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 0.6 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.2 0.7 GO:0004061 arylformamidase activity(GO:0004061)
0.2 0.6 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 3.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 1.0 GO:0070698 type I activin receptor binding(GO:0070698)
0.2 0.7 GO:0004046 aminoacylase activity(GO:0004046)
0.2 0.5 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.2 0.5 GO:0035515 DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
0.2 1.4 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 1.3 GO:0030619 U1 snRNA binding(GO:0030619)
0.1 0.7 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.6 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 2.6 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.8 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.8 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.7 GO:0004335 galactokinase activity(GO:0004335)
0.1 2.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 1.4 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 0.5 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 4.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 2.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.4 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 0.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.7 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 1.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.3 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.6 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.3 GO:0070513 death domain binding(GO:0070513)
0.1 2.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 1.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 1.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 3.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.4 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.1 0.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.7 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 0.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.6 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
0.1 0.6 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 2.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 2.4 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.1 0.1 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.1 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 4.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 1.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.2 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.1 0.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.5 GO:0005009 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.1 1.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 3.5 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.1 0.2 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.3 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.1 0.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 1.6 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 17.5 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 0.2 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.1 0.4 GO:0071253 connexin binding(GO:0071253)
0.1 0.2 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.1 3.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0008465 glycerate dehydrogenase activity(GO:0008465)
0.0 0.6 GO:0008483 transaminase activity(GO:0008483)
0.0 1.0 GO:0015296 anion:cation symporter activity(GO:0015296)
0.0 0.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.4 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 3.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.3 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 3.8 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.9 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 1.1 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.9 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.3 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.7 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.4 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 2.6 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 6.9 GO:0003924 GTPase activity(GO:0003924)
0.0 0.6 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.4 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.0 0.4 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 1.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.8 GO:0005525 GTP binding(GO:0005525)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 2.2 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.8 GO:0045296 cadherin binding(GO:0045296)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 2.3 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 PID S1P S1P3 PATHWAY S1P3 pathway
0.2 2.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.7 PID LKB1 PATHWAY LKB1 signaling events
0.1 5.1 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 1.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 0.8 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 2.0 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 1.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 2.4 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.5 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.2 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.3 PID AURORA A PATHWAY Aurora A signaling
0.0 0.7 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.4 PID BARD1 PATHWAY BARD1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.3 1.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.3 3.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 0.7 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.2 1.9 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 0.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 1.7 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 2.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 2.6 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.0 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
0.1 1.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 0.8 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 1.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 0.4 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 0.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 2.8 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.1 0.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 0.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.0 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.2 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 1.5 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.3 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation