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Results for myf6
Z-value: 1.74
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Transcription factors associated with myf6
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| myf6 | dr10_dc_chr4_+_21996784_21996805 | -0.72 | 1.5e-03 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of myf6
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_-_73890950 Show fit | 6.41 |
ENSDART00000164992
|
RNA binding protein with multiple splicing |
|
| chr7_-_73890817 Show fit | 4.56 |
ENSDART00000164992
|
RNA binding protein with multiple splicing |
|
| chr7_-_59284273 Show fit | 3.97 |
ENSDART00000008554
|
La ribonucleoprotein domain family, member 7 |
|
| chr7_-_59284362 Show fit | 3.75 |
ENSDART00000101731
|
La ribonucleoprotein domain family, member 7 |
|
| chr19_-_27093095 Show fit | 3.23 |
|
|
|
| chr1_-_30299017 Show fit | 2.90 |
|
|
|
| chr1_-_44892852 Show fit | 2.43 |
ENSDART00000160961
|
activating transcription factor 7 interacting protein |
|
| chr12_+_30673985 Show fit | 2.38 |
ENSDART00000160422
|
aldehyde dehydrogenase 18 family, member A1 |
|
| chr6_+_135002 Show fit | 2.31 |
ENSDART00000097468
|
zinc finger, GATA-like protein 1 |
|
| chr7_+_17848688 Show fit | 2.28 |
ENSDART00000055810
|
zRAB1B, member RAS oncogene family a |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 10.5 | GO:0030218 | erythrocyte differentiation(GO:0030218) erythrocyte homeostasis(GO:0034101) |
| 2.5 | 10.0 | GO:1990437 | snRNA 2'-O-methylation(GO:1990437) U6 2'-O-snRNA methylation(GO:1990438) |
| 0.5 | 6.1 | GO:0090309 | methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
| 0.1 | 5.6 | GO:0048599 | oocyte development(GO:0048599) |
| 0.2 | 4.5 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.5 | 4.3 | GO:0046850 | regulation of bone remodeling(GO:0046850) |
| 0.0 | 4.2 | GO:0016579 | protein deubiquitination(GO:0016579) |
| 0.0 | 4.0 | GO:0000398 | RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398) |
| 0.3 | 3.7 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.0 | 3.7 | GO:0006006 | glucose metabolic process(GO:0006006) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 15.6 | GO:0005654 | nucleoplasm(GO:0005654) |
| 0.1 | 8.4 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 8.4 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.1 | 5.3 | GO:0000786 | nucleosome(GO:0000786) |
| 0.5 | 5.2 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.1 | 5.0 | GO:0032432 | actin filament bundle(GO:0032432) |
| 0.0 | 4.3 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 3.2 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.2 | 2.8 | GO:0005845 | mRNA cap binding complex(GO:0005845) |
| 0.1 | 2.7 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 17.5 | GO:0003729 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 2.0 | 10.0 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.0 | 6.9 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.1 | 4.8 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.1 | 4.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.0 | 3.8 | GO:0042803 | protein homodimerization activity(GO:0042803) |
| 0.0 | 3.6 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.1 | 3.5 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.1 | 3.5 | GO:0008408 | 3'-5' exonuclease activity(GO:0008408) |
| 0.1 | 3.4 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.1 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.1 | 3.7 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.2 | 2.8 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.0 | 2.4 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.2 | 2.2 | PID S1P S1P3 PATHWAY | S1P3 pathway |
| 0.1 | 2.0 | PID HIV NEF PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
| 0.1 | 1.4 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.1 | 1.2 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 0.9 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.1 | 0.8 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 3.2 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.1 | 2.8 | REACTOME SIGNALING BY SCF KIT | Genes involved in Signaling by SCF-KIT |
| 0.1 | 2.6 | REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
| 0.1 | 2.2 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.2 | 1.9 | REACTOME ANDROGEN BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
| 0.1 | 1.8 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.1 | 1.8 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.2 | 1.7 | REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
| 0.1 | 1.5 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.0 | 1.5 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |