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Results for myod1

Z-value: 2.41

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Transcription factors associated with myod1

Gene Symbol Gene ID Gene Info
myod1
ENSDARG00000030110 myogenic differentiation 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
myod1dr10_dc_chr25_-_30845998_308460120.901.5e-06Click!

Activity profile of myod1 motif

Sorted Z-values of myod1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of myod1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr8_-_11191783 8.49 ENSDART00000131171
unc45b
unc-45 myosin chaperone B
chr8_-_985673 7.23 ENSDART00000170737
smyd1b
SET and MYND domain containing 1b
chr17_-_124685 7.23 ENSDART00000158825
actc1b
actin, alpha, cardiac muscle 1b
chr7_+_49442972 7.21 ENSDART00000019446
ascl1b
achaete-scute family bHLH transcription factor 1b
chr7_+_39131795 6.30 ENSDART00000025852
tnni2b.1
troponin I type 2b (skeletal, fast), tandem duplicate 1
chr7_+_6517248 5.92 ENSDART00000102681
pnp5a
purine nucleoside phosphorylase 5a
chr11_-_5868257 5.84 ENSDART00000104360
gamt
guanidinoacetate N-methyltransferase
chr8_-_7049946 5.68 ENSDART00000045669
ENSDART00000162950
KRT73
keratin 73
chr22_+_26543146 5.61

chr21_-_25704662 5.47 ENSDART00000101211
cldnh
claudin h
chr6_-_42006033 5.40 ENSDART00000032527
cav3
caveolin 3
chr21_+_27346176 5.10 ENSDART00000005682
actn3a
actinin alpha 3a
chr20_-_19646761 4.98

chr3_+_32394653 4.87 ENSDART00000150897
si:ch73-367p23.2
si:ch73-367p23.2
chr6_+_3519697 4.83 ENSDART00000013588
klhl41b
kelch-like family member 41b
chr16_+_46327528 4.79 ENSDART00000040769
nr2f5
nuclear receptor subfamily 2, group F, member 5
chr24_+_7832020 4.66 ENSDART00000019705
bmp6
bone morphogenetic protein 6
chr7_+_40972616 4.60 ENSDART00000173814
scrib
scribbled planar cell polarity protein
chr2_+_55859099 4.42 ENSDART00000097753
ENSDART00000141688
nmrk2
nicotinamide riboside kinase 2
chr17_-_32473712 4.34 ENSDART00000148455
ENSDART00000149885
grhl1
grainyhead-like transcription factor 1
chr11_-_18542803 4.26 ENSDART00000059732
id1
inhibitor of DNA binding 1
chr9_-_23081250 4.26

chr24_-_33817169 4.23 ENSDART00000079292
cavin4b
caveolae associated protein 4b
chr16_-_42990753 4.04 ENSDART00000149317
hfe2
hemochromatosis type 2
chr22_-_613948 4.04 ENSDART00000148692
apobec2a
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a
chr17_+_27417635 4.03 ENSDART00000052446
vgll2b
vestigial-like family member 2b
chr24_+_20430778 4.00 ENSDART00000010488
klhl40b
kelch-like family member 40b
chr10_+_33227967 3.98 ENSDART00000159666
myl10
myosin, light chain 10, regulatory
chr10_+_15819127 3.95 ENSDART00000140511
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr15_+_19902697 3.94 ENSDART00000101204
alcamb
activated leukocyte cell adhesion molecule b
chr2_-_21677086 3.94 ENSDART00000057022
klhl40a
kelch-like family member 40a
chr18_+_38307946 3.89 ENSDART00000134247
lmo2
LIM domain only 2 (rhombotin-like 1)
chr20_-_32543497 3.88 ENSDART00000026635
nr2e1
nuclear receptor subfamily 2, group E, member 1
chr12_-_36138709 3.86 ENSDART00000130985
st6galnac
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase
chr6_+_7092350 3.82 ENSDART00000049695
ENSDART00000136088
ENSDART00000083424
ENSDART00000125912
dzip1
DAZ interacting zinc finger protein 1
chr20_+_35010140 3.80 ENSDART00000172001
snap25a
synaptosomal-associated protein, 25a
chr1_+_38834751 3.78 ENSDART00000137676
tenm3
teneurin transmembrane protein 3
chr4_+_12033088 3.78 ENSDART00000044154
tnnt2c
troponin T2c, cardiac
chr10_+_42530040 3.77 ENSDART00000025691
dbnla
drebrin-like a
chr6_+_47845002 3.71 ENSDART00000140943
padi2
peptidyl arginine deiminase, type II
chr11_-_41357639 3.69 ENSDART00000055709
her2
hairy-related 2
chr22_+_21997000 3.56 ENSDART00000046174
gna15.1
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1
chr22_-_14103942 3.54 ENSDART00000140323
ENSDARG00000042857
ENSDARG00000042857
chr24_+_17125429 3.51 ENSDART00000017605
spag6
sperm associated antigen 6
chr12_+_31558667 3.48 ENSDART00000152971
dnmbp
dynamin binding protein
chr3_-_31672763 3.46 ENSDART00000028270
gfap
glial fibrillary acidic protein
chr3_+_37433008 3.41 ENSDART00000055225
wnt9b
wingless-type MMTV integration site family, member 9B
chr23_-_3466041 3.40 ENSDART00000002309
mafba
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba
chr1_+_51925783 3.38 ENSDART00000167514
abca1a
ATP-binding cassette, sub-family A (ABC1), member 1A
chr11_-_42934175 3.37 ENSDART00000172929
sptbn1
spectrin, beta, non-erythrocytic 1
chr15_-_15421065 3.35 ENSDART00000106120
ywhag2
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2
chr11_-_22211478 3.33 ENSDART00000065996
tmem183a
transmembrane protein 183A
KN149932v1_+_27584 3.30

chr14_-_30363703 3.27 ENSDART00000134098
efemp2a
EGF containing fibulin-like extracellular matrix protein 2a
chr24_+_4341242 3.26 ENSDART00000133360
ccny
cyclin Y
chr19_-_22894525 3.17 ENSDART00000090679
pleca
plectin a
chr21_+_549788 3.16 ENSDART00000175116
CABZ01100207.1
ENSDARG00000106163
chr7_+_58718614 3.14 ENSDART00000157873
hacd1
3-hydroxyacyl-CoA dehydratase 1
chr14_+_5852295 3.14 ENSDART00000128638
bscl2l
Bernardinelli-Seip congenital lipodystrophy 2, like
chr10_+_19069375 3.14 ENSDART00000111952
igsf9a
immunoglobulin superfamily, member 9a
chr14_-_17258072 3.11 ENSDART00000082667
fgfrl1a
fibroblast growth factor receptor-like 1a
chr14_-_32704626 3.11 ENSDART00000170626
kdrl
kinase insert domain receptor like
chr16_+_39396358 3.07

chr17_-_5816135 3.04

chr10_+_16634200 3.04 ENSDART00000101142
chsy3
chondroitin sulfate synthase 3
chr10_+_31358236 3.03 ENSDART00000145562
robo4
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr18_+_23198330 3.02 ENSDART00000143977
mef2aa
myocyte enhancer factor 2aa
chr11_-_32461160 3.02 ENSDART00000155592
pcdh17
protocadherin 17
chr5_+_36093701 3.01 ENSDART00000019259
dlb
deltaB
chr16_+_5625301 2.99

chr14_+_21816442 2.99 ENSDART00000109759
tmx2a
thioredoxin-related transmembrane protein 2a
chr22_+_11726312 2.98 ENSDART00000155366
krt96
keratin 96
chr2_-_32372801 2.97 ENSDART00000143348
BX663499.1
ENSDARG00000093778
chr16_+_3090170 2.95 ENSDART00000110395
limd1a
LIM domains containing 1a
chr11_+_41401893 2.94 ENSDART00000171655
AL929185.1
ENSDARG00000103982
chr18_+_38773971 2.92 ENSDART00000010177
onecut1
one cut homeobox 1
chr5_-_39910235 2.90 ENSDART00000146237
ENSDART00000163302
fsta
follistatin a
chr16_+_29716279 2.89 ENSDART00000137153
tmod4
tropomodulin 4 (muscle)
chr24_-_2278409 2.88

chr6_-_42006225 2.87 ENSDART00000032527
cav3
caveolin 3
chr23_+_36832325 2.86

chr8_+_46319434 2.83 ENSDART00000145618
si:dkey-75a21.2
si:dkey-75a21.2
chr4_-_76620869 2.83

chr22_-_14103803 2.83 ENSDART00000062902
ENSDARG00000042857
ENSDARG00000042857
chr21_-_7703717 2.81 ENSDART00000158852
egfl7
EGF-like-domain, multiple 7
KN149968v1_+_15749 2.81 ENSDART00000168977
ENSDARG00000102503
ENSDARG00000102503
chr12_+_22734974 2.78 ENSDART00000130594
afap1
actin filament associated protein 1
chr6_-_39053400 2.78 ENSDART00000165839
tns2b
tensin 2b
chr16_-_14184394 2.75 ENSDART00000090234
trim109
tripartite motif containing 109
chr7_-_69639922 2.75

chr20_+_27068031 2.74 ENSDART00000153294
ahsa1a
AHA1, activator of heat shock protein ATPase homolog 1a
chr1_-_50147413 2.71 ENSDART00000080389
fam13a
family with sequence similarity 13, member A
chr22_+_24131239 2.71 ENSDART00000159165
b3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr5_-_40133824 2.71 ENSDART00000010896
isl1
ISL LIM homeobox 1
chr2_-_44402486 2.70 ENSDART00000011188
ENSDART00000093298
atp1a2a
ATPase, Na+/K+ transporting, alpha 2a polypeptide
chr2_-_42784609 2.67

chr1_-_40208469 2.64 ENSDART00000027463
hmx4
H6 family homeobox 4
chr18_-_6494014 2.61 ENSDART00000062423
tnni1c
troponin I, skeletal, slow c
chr6_-_9964616 2.61

chr10_+_26020615 2.60 ENSDART00000128292
ENSDART00000170275
ENSDART00000166164
ENSDART00000108808
frem2a
Fras1 related extracellular matrix protein 2a
chr23_+_20522512 2.58 ENSDART00000137294
slc35c2
solute carrier family 35 (GDP-fucose transporter), member C2
chr16_+_5256773 2.56 ENSDART00000012053
elovl4a
ELOVL fatty acid elongase 4a
chr13_-_7435355 2.56 ENSDART00000121952
h2afy2
H2A histone family, member Y2
chr11_+_3940085 2.55 ENSDART00000122953
gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr13_-_7434672 2.55 ENSDART00000159453
h2afy2
H2A histone family, member Y2
chr13_-_49983998 2.51

chr15_-_12484651 2.50 ENSDART00000162258
BX901957.1
ENSDARG00000098363
chr20_+_34417665 2.48 ENSDART00000153207
ivns1abpa
influenza virus NS1A binding protein a
chr11_-_6004509 2.47 ENSDART00000108628
ano8b
anoctamin 8b
chr18_-_3244618 2.46 ENSDART00000161520
gdpd4a
glycerophosphodiester phosphodiesterase domain containing 4a
chr19_-_6466494 2.45 ENSDART00000104950
atp1a3a
ATPase, Na+/K+ transporting, alpha 3a polypeptide
chr8_+_999710 2.45 ENSDART00000081432
sprb
sepiapterin reductase b
chr11_-_25803101 2.44 ENSDART00000088888
kaznb
kazrin, periplakin interacting protein b
KN150487v1_+_15409 2.42 ENSDART00000166996
CABZ01074304.1
ENSDARG00000100224
chr10_+_34377959 2.41

chr19_-_7531709 2.39 ENSDART00000104750
mllt11
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11
chr4_-_24298444 2.37 ENSDART00000077926
ENSDART00000128368
celf2
cugbp, Elav-like family member 2
chr19_+_1626598 2.35 ENSDART00000163539
scrt1a
scratch family zinc finger 1a
chr7_-_70219217 2.35 ENSDART00000097710
ppargc1a
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr23_+_35964754 2.34 ENSDART00000103147
hoxc12a
homeobox C12a
chr14_-_45887823 2.33 ENSDART00000178932
ENSDART00000160657
cltb
clathrin, light chain B
chr23_+_2193582 2.32 ENSDART00000106336
cpeb2
cytoplasmic polyadenylation element binding protein 2
chr1_-_40587797 2.31 ENSDART00000170895
rgs12b
regulator of G protein signaling 12b
chr13_-_31165867 2.31 ENSDART00000030946
prdm8
PR domain containing 8
chr22_+_16282153 2.30 ENSDART00000162685
ENSDART00000105678
lrrc39
leucine rich repeat containing 39
chr21_+_17505748 2.28 ENSDART00000163238
stom
stomatin
chr10_-_28474085 2.26

chr22_+_11745592 2.26 ENSDART00000140272
krt96
keratin 96
chr24_-_33817036 2.26 ENSDART00000079292
cavin4b
caveolae associated protein 4b
chr12_+_18403055 2.26 ENSDART00000090332
neurl2
neuralized E3 ubiquitin protein ligase 2
chr4_-_4825948 2.25 ENSDART00000141539
coa6
cytochrome c oxidase assembly factor 6
chr7_-_38288929 2.25

chr16_+_55167489 2.25 ENSDART00000149795
nr0b2a
nuclear receptor subfamily 0, group B, member 2a
chr19_+_41488385 2.25 ENSDART00000138687
ppp1r9a
protein phosphatase 1, regulatory subunit 9A
chr14_+_24543732 2.24 ENSDART00000106039
arhgef37
Rho guanine nucleotide exchange factor (GEF) 37
chr17_+_27383737 2.24 ENSDART00000156756
FP017274.1
ENSDARG00000097369
chr14_-_41311458 2.23 ENSDART00000163039
fgfrl1b
fibroblast growth factor receptor-like 1b
chr17_+_52736192 2.22 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr2_-_42279180 2.22 ENSDART00000047055
trim55a
tripartite motif containing 55a
chr15_-_47277391 2.22 ENSDART00000151600
h3f3b.1
H3 histone, family 3B.1
chr11_-_42933969 2.21 ENSDART00000172929
sptbn1
spectrin, beta, non-erythrocytic 1
chr9_+_30774173 2.20 ENSDART00000160590
tbc1d4
TBC1 domain family, member 4
chr14_-_32877752 2.20 ENSDART00000163046
si:dkey-31j3.11
si:dkey-31j3.11
chr17_+_38314814 2.19 ENSDART00000017493
nkx2.1
NK2 homeobox 1
chr6_+_1873957 2.19

chr13_+_41998500 2.19 ENSDART00000074707
cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr8_-_50299273 2.19 ENSDART00000023639
nkx2.7
NK2 transcription factor related 7
chr1_-_48853800 2.19 ENSDART00000137357
zgc:175214
zgc:175214
chr1_-_24297477 2.18

chr15_-_20297270 2.17 ENSDART00000123910
ppp1r14ab
protein phosphatase 1, regulatory (inhibitor) subunit 14Ab
KN149909v1_+_1319 2.16

chr2_-_53210330 2.16 ENSDART00000024629
rab31
RAB31, member RAS oncogene family
chr15_+_15580544 2.16 ENSDART00000016024
traf4a
tnf receptor-associated factor 4a
chr5_-_47656197 2.15

chr7_-_29021031 2.15 ENSDART00000086753
dapk2a
death-associated protein kinase 2a
chr6_+_52064243 2.14 ENSDART00000153468
abraa
actin binding Rho activating protein a
chr3_-_44113070 2.14 ENSDART00000160717
znf750
zinc finger protein 750
chr16_+_46435014 2.13 ENSDART00000144000
rpz2
rapunzel 2
chr17_-_6219019 2.13

chr15_+_9351511 2.11 ENSDART00000144381
sgcg
sarcoglycan, gamma
chr7_-_18629056 2.11 ENSDART00000021502
mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr10_-_23939618 2.10

chr23_-_24755654 2.09 ENSDART00000104035
ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr8_+_53173227 2.09 ENSDART00000131514
nadka
NAD kinase a
chr12_+_30245620 2.09 ENSDART00000153116
ENSDART00000152900
ENSDARG00000020224
ENSDARG00000020224
chr21_-_25704793 2.08 ENSDART00000101211
cldnh
claudin h
chr3_+_14238188 2.06 ENSDART00000165452
ENSDART00000171726
tmem56b
transmembrane protein 56b
chr10_-_8336541 2.06 ENSDART00000163803
plpp1a
phospholipid phosphatase 1a
chr16_-_29229687 2.05 ENSDART00000132589
mef2d
myocyte enhancer factor 2d
chr17_+_45824480 2.05

chr18_+_9524331 2.04 ENSDART00000053125
sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr15_-_4537178 2.04 ENSDART00000155619
ENSDART00000128602
tfdp2
transcription factor Dp-2
chr3_-_19218660 2.04 ENSDART00000132987
s1pr5a
sphingosine-1-phosphate receptor 5a
chr8_-_23744125 2.03 ENSDART00000141871
INAVA
innate immunity activator
chr6_-_49674729 2.03 ENSDART00000112226
apcdd1l
adenomatosis polyposis coli down-regulated 1-like
chr17_+_53224434 2.03 ENSDART00000166517
asb2b
ankyrin repeat and SOCS box containing 2b
chr20_+_51388214 2.03 ENSDART00000153452
hsp90ab1
heat shock protein 90, alpha (cytosolic), class B member 1
chr6_-_39767452 2.03 ENSDART00000085277
pfkmb
phosphofructokinase, muscle b
chr1_-_37990863 2.02 ENSDART00000132402
gpm6ab
glycoprotein M6Ab
chr3_+_42380497 2.01 ENSDART00000163579
si:dkey-43p13.5
si:dkey-43p13.5
chr6_+_45917081 2.01 ENSDART00000149450
ENSDART00000149642
h6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr20_-_21773202 2.01 ENSDART00000133286
si:ch211-207i1.2
si:ch211-207i1.2
chr8_-_37011436 2.00 ENSDART00000139567
renbp
renin binding protein
chr23_-_20402258 2.00 ENSDART00000136204
CR749762.2
ENSDARG00000093223
chr15_+_24064257 2.00 ENSDART00000156714
CR394545.1
ENSDARG00000097097
chr5_-_54150484 1.99 ENSDART00000058470
pik3r1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr19_-_5453469 1.99 ENSDART00000105004
krt17
keratin 17
chr10_+_32739166 1.99 ENSDART00000063551
ppm1e
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr18_+_30391910 1.97 ENSDART00000158871
gse1
Gse1 coiled-coil protein
chr10_+_33926312 1.97 ENSDART00000174730
BX569785.2
ENSDARG00000106629
chr3_-_36339966 1.96 ENSDART00000176547
ppl
periplakin
chr19_-_5452918 1.96 ENSDART00000105004
krt17
keratin 17
chr1_-_10391257 1.95 ENSDART00000102903
dmd
dystrophin
chr25_-_34648956 1.95 ENSDART00000154851
zgc:153405
zgc:153405
chr25_-_16658906 1.94 ENSDART00000124729
ENSDART00000110859
ribc2
RIB43A domain with coiled-coils 2
chr1_-_51862897 1.94 ENSDART00000136469
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr24_+_21200975 1.93 ENSDART00000126519
shisa2b
shisa family member 2b
chr7_+_31567166 1.91 ENSDART00000099785
ENSDART00000122506
mybpc3
myosin binding protein C, cardiac
chr21_-_4842528 1.90 ENSDART00000097796
rnf165a
ring finger protein 165a
KN149970v1_-_1072 1.89

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.1 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
1.9 5.8 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
1.4 4.3 GO:0010084 specification of organ axis polarity(GO:0010084)
1.3 4.0 GO:0051101 regulation of DNA binding(GO:0051101)
1.3 3.8 GO:1903385 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
1.3 5.0 GO:0071634 transforming growth factor beta activation(GO:0036363) transforming growth factor beta production(GO:0071604) regulation of transforming growth factor beta production(GO:0071634) negative regulation of transforming growth factor beta production(GO:0071635) regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
1.1 3.4 GO:0021742 abducens nucleus development(GO:0021742)
1.1 4.3 GO:0003334 keratinocyte development(GO:0003334)
1.0 9.2 GO:0001765 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
1.0 7.1 GO:0048769 sarcomerogenesis(GO:0048769)
1.0 6.8 GO:0061162 establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.9 3.8 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.9 5.3 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.8 3.3 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.8 2.4 GO:0072025 distal convoluted tubule development(GO:0072025) late distal convoluted tubule development(GO:0072068)
0.7 3.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.6 6.5 GO:0033292 T-tubule organization(GO:0033292)
0.6 2.6 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.6 1.9 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.6 3.7 GO:0007405 neuroblast proliferation(GO:0007405)
0.6 3.1 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881) membrane depolarization(GO:0051899) regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.6 5.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.6 2.3 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.6 3.4 GO:0032374 regulation of sterol transport(GO:0032371) regulation of cholesterol transport(GO:0032374)
0.6 1.7 GO:0003091 renal water homeostasis(GO:0003091) renal water transport(GO:0003097) carbon dioxide transport(GO:0015670)
0.5 4.2 GO:0003207 cardiac chamber formation(GO:0003207)
0.5 1.5 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
0.5 2.5 GO:0031646 positive regulation of neurological system process(GO:0031646)
0.5 2.9 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.5 2.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.5 11.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.5 2.8 GO:2001239 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.5 3.3 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.5 1.9 GO:0030104 water homeostasis(GO:0030104)
0.5 1.8 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.4 3.0 GO:0060148 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.4 2.4 GO:0071688 myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.4 1.4 GO:0060259 positive regulation of epithelial cell differentiation(GO:0030858) regulation of feeding behavior(GO:0060259)
0.4 1.1 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.4 2.8 GO:0030183 B cell differentiation(GO:0030183)
0.3 4.1 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.3 12.9 GO:0045214 sarcomere organization(GO:0045214)
0.3 3.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.3 3.8 GO:0016082 synaptic vesicle priming(GO:0016082)
0.3 4.4 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.3 3.1 GO:0021592 fourth ventricle development(GO:0021592)
0.3 3.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.3 3.6 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.3 0.6 GO:0051660 establishment of centrosome localization(GO:0051660)
0.3 1.7 GO:0060579 ventral spinal cord interneuron fate commitment(GO:0060579)
0.3 3.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.3 2.0 GO:0061718 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.3 0.9 GO:0052803 imidazole-containing compound metabolic process(GO:0052803) imidazole-containing compound catabolic process(GO:0052805)
0.3 1.7 GO:0033198 response to ATP(GO:0033198)
0.3 2.2 GO:0034389 lipid particle organization(GO:0034389)
0.3 4.8 GO:0032526 response to retinoic acid(GO:0032526)
0.3 1.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.3 1.5 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.2 2.4 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.2 1.2 GO:2000651 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.2 2.6 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.2 2.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 2.0 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 1.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 8.5 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.2 1.9 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.2 1.3 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.2 1.5 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.2 1.0 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 2.6 GO:1900052 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.2 2.0 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.2 3.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 1.2 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 0.6 GO:2000136 cell proliferation involved in heart morphogenesis(GO:0061323) regulation of cell proliferation involved in heart morphogenesis(GO:2000136)
0.2 0.8 GO:0015865 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.2 1.1 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.2 1.1 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.2 3.3 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.2 5.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 2.9 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 1.7 GO:0042572 retinol metabolic process(GO:0042572)
0.2 3.0 GO:0097120 receptor localization to synapse(GO:0097120)
0.2 3.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 0.7 GO:2001032 positive regulation of double-strand break repair via homologous recombination(GO:1905168) regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.2 2.5 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.2 2.1 GO:0045471 response to ethanol(GO:0045471)
0.2 1.9 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.2 1.4 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.2 3.1 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 3.1 GO:0030878 thyroid gland development(GO:0030878)
0.2 0.9 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.2 0.3 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.2 2.1 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.1 1.0 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 4.2 GO:0030835 regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835) actin filament capping(GO:0051693)
0.1 0.7 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 2.0 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 3.0 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 1.2 GO:0032264 IMP salvage(GO:0032264)
0.1 1.8 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.1 1.0 GO:0090178 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 2.3 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 1.1 GO:0044211 pyrimidine-containing compound salvage(GO:0008655) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206) CTP salvage(GO:0044211)
0.1 2.0 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 2.3 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.1 4.9 GO:0021575 hindbrain morphogenesis(GO:0021575)
0.1 1.0 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 2.3 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 0.8 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 0.7 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 1.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 5.5 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.1 3.8 GO:0050768 negative regulation of neurogenesis(GO:0050768)
0.1 1.3 GO:0061337 cardiac conduction(GO:0061337)
0.1 0.3 GO:1903059 N-terminal protein palmitoylation(GO:0006500) regulation of lipoprotein metabolic process(GO:0050746) negative regulation of lipoprotein metabolic process(GO:0050748) regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) regulation of protein lipidation(GO:1903059) negative regulation of protein lipidation(GO:1903060)
0.1 1.0 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 2.2 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.1 0.3 GO:0046655 folic acid metabolic process(GO:0046655)
0.1 1.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 4.8 GO:0021782 glial cell development(GO:0021782)
0.1 2.0 GO:0048484 enteric nervous system development(GO:0048484)
0.1 0.5 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 2.8 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 3.4 GO:0030901 midbrain development(GO:0030901)
0.1 1.5 GO:0060729 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.1 0.5 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 1.4 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 1.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.2 GO:0090153 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 0.2 GO:0010259 multicellular organism aging(GO:0010259)
0.1 7.2 GO:0060047 heart contraction(GO:0060047)
0.1 1.0 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.1 2.0 GO:0030497 fatty acid elongation(GO:0030497)
0.1 5.2 GO:0031101 fin regeneration(GO:0031101)
0.1 2.2 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 0.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 0.4 GO:0043173 nucleotide salvage(GO:0043173)
0.1 6.1 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.1 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.8 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 0.5 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 0.9 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 2.0 GO:1902850 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.1 0.1 GO:0048211 Golgi vesicle docking(GO:0048211)
0.1 1.0 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.1 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.1 0.3 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.1 0.4 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.1 2.2 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.1 1.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 2.6 GO:0033334 fin morphogenesis(GO:0033334)
0.0 7.2 GO:0007268 chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916)
0.0 1.7 GO:0032456 endocytic recycling(GO:0032456)
0.0 2.1 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.7 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.3 GO:0010906 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 2.0 GO:0006469 negative regulation of protein kinase activity(GO:0006469) negative regulation of kinase activity(GO:0033673)
0.0 1.8 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 1.9 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 0.8 GO:0030239 myofibril assembly(GO:0030239)
0.0 1.0 GO:0035272 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.0 0.2 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 1.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.4 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 2.1 GO:0008544 epidermis development(GO:0008544)
0.0 0.2 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 5.3 GO:0009116 nucleoside metabolic process(GO:0009116)
0.0 1.8 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.5 GO:0036269 swimming behavior(GO:0036269)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.3 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.7 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.5 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.2 GO:0034340 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 4.6 GO:0098609 cell-cell adhesion(GO:0098609)
0.0 0.9 GO:0042471 ear morphogenesis(GO:0042471)
0.0 1.4 GO:0043068 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.0 0.3 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 1.0 GO:0007051 spindle organization(GO:0007051)
0.0 0.5 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.3 GO:0001570 vasculogenesis(GO:0001570)
0.0 0.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 25.8 GO:0031672 A band(GO:0031672)
1.2 3.5 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
1.0 4.9 GO:0008091 spectrin(GO:0008091)
0.7 15.6 GO:0005861 troponin complex(GO:0005861)
0.6 1.8 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.6 7.3 GO:0005869 dynactin complex(GO:0005869)
0.5 4.4 GO:0002102 podosome(GO:0002102)
0.5 15.9 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.4 2.9 GO:0044295 axonal growth cone(GO:0044295)
0.4 2.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.3 1.2 GO:0070062 extracellular exosome(GO:0070062)
0.3 1.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.3 3.2 GO:0030056 hemidesmosome(GO:0030056)
0.3 2.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.3 1.1 GO:0033263 CORVET complex(GO:0033263)
0.3 3.8 GO:0031083 BLOC-1 complex(GO:0031083)
0.3 4.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 3.0 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.2 2.9 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.2 4.1 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.2 2.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 1.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 5.7 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.2 1.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 2.6 GO:0071564 npBAF complex(GO:0071564)
0.2 1.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 1.7 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.2 2.0 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 2.8 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 1.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 10.0 GO:0005882 intermediate filament(GO:0005882)
0.1 4.1 GO:0060076 excitatory synapse(GO:0060076)
0.1 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.3 GO:0016586 RSC complex(GO:0016586)
0.1 6.2 GO:0005795 Golgi stack(GO:0005795)
0.1 11.4 GO:0030424 axon(GO:0030424)
0.1 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.1 4.1 GO:0005581 collagen trimer(GO:0005581)
0.1 5.0 GO:0030017 sarcomere(GO:0030017)
0.1 1.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 1.4 GO:0032587 ruffle membrane(GO:0032587)
0.1 1.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 8.7 GO:0005911 cell-cell junction(GO:0005911)
0.1 4.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 2.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 2.8 GO:0005814 centriole(GO:0005814)
0.1 3.1 GO:0030425 dendrite(GO:0030425)
0.0 1.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 8.7 GO:0043235 receptor complex(GO:0043235)
0.0 2.1 GO:0005924 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 5.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.6 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 1.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.3 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 4.3 GO:0030054 cell junction(GO:0030054)
0.0 1.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 16.5 GO:0005615 extracellular space(GO:0005615)
0.0 2.8 GO:0009986 cell surface(GO:0009986)
0.0 0.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.0 GO:0030027 lamellipodium(GO:0030027)
0.0 1.4 GO:0043005 neuron projection(GO:0043005)
0.0 0.2 GO:0035371 microtubule plus-end(GO:0035371)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 5.9 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
1.3 4.0 GO:0004126 cytidine deaminase activity(GO:0004126)
1.3 9.2 GO:0071253 connexin binding(GO:0071253)
1.0 3.1 GO:0102345 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.9 4.4 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.8 12.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.7 2.8 GO:0042169 SH2 domain binding(GO:0042169)
0.7 2.0 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.7 6.7 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.6 2.6 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.6 3.0 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.6 1.7 GO:0070330 aromatase activity(GO:0070330)
0.6 3.4 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.6 1.7 GO:0015166 polyol transmembrane transporter activity(GO:0015166) glycerol transmembrane transporter activity(GO:0015168)
0.5 2.0 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.5 6.7 GO:0005523 tropomyosin binding(GO:0005523)
0.5 1.8 GO:0016936 galactoside binding(GO:0016936)
0.4 1.3 GO:0030553 cGMP-dependent protein kinase activity(GO:0004692) cGMP binding(GO:0030553)
0.4 7.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.4 3.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.4 5.5 GO:0038191 neuropilin binding(GO:0038191)
0.4 5.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.4 1.8 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.4 1.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3 5.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.3 1.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.3 2.8 GO:0070700 BMP receptor binding(GO:0070700)
0.3 4.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.3 3.2 GO:0030506 ankyrin binding(GO:0030506)
0.3 2.0 GO:0003872 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.3 1.7 GO:0004931 purinergic nucleotide receptor activity(GO:0001614) extracellular ATP-gated cation channel activity(GO:0004931) nucleotide receptor activity(GO:0016502) ATP-gated ion channel activity(GO:0035381)
0.3 1.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.3 2.9 GO:0048185 activin binding(GO:0048185)
0.3 1.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.3 2.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.3 1.5 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.3 2.0 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 1.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 1.2 GO:0019870 chloride channel regulator activity(GO:0017081) chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.2 1.8 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.2 0.9 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.2 2.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 0.8 GO:0099528 G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.2 0.6 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 0.8 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.2 1.1 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.2 2.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.2 3.3 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.2 0.7 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.2 1.0 GO:0005231 excitatory extracellular ligand-gated ion channel activity(GO:0005231)
0.2 0.7 GO:0004046 aminoacylase activity(GO:0004046)
0.2 0.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 2.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 2.0 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.2 1.9 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.2 1.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.2 0.8 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 1.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.7 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 2.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.1 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 4.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 2.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 2.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 2.3 GO:0005112 Notch binding(GO:0005112)
0.1 2.0 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 4.4 GO:0005109 frizzled binding(GO:0005109)
0.1 3.9 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 12.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 2.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 7.9 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 2.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 3.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 3.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 1.6 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.1 12.2 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.1 3.0 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.1 1.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 1.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 1.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 4.6 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 2.3 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 0.4 GO:0048156 tau protein binding(GO:0048156)
0.1 0.9 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 1.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.5 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 1.5 GO:0044325 ion channel binding(GO:0044325)
0.1 1.5 GO:0004180 carboxypeptidase activity(GO:0004180)
0.1 1.3 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.7 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 27.3 GO:0046983 protein dimerization activity(GO:0046983)
0.1 2.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 3.9 GO:0042802 identical protein binding(GO:0042802)
0.1 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 1.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.3 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.8 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 1.2 GO:0051087 chaperone binding(GO:0051087)
0.0 9.5 GO:0051015 actin filament binding(GO:0051015)
0.0 4.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.4 GO:0005179 hormone activity(GO:0005179)
0.0 17.3 GO:0005198 structural molecule activity(GO:0005198)
0.0 4.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0032977 membrane insertase activity(GO:0032977)
0.0 1.0 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 1.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.0 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 7.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 4.5 GO:0019901 protein kinase binding(GO:0019901)
0.0 1.6 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 2.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 2.5 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 4.6 GO:0008168 methyltransferase activity(GO:0008168)
0.0 0.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.9 GO:0020037 heme binding(GO:0020037)
0.0 0.9 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 10.0 GO:0005509 calcium ion binding(GO:0005509)
0.0 20.8 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 2.5 GO:0003779 actin binding(GO:0003779)
0.0 0.2 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.3 4.3 PID ALK1 PATHWAY ALK1 signaling events
0.3 9.0 PID BMP PATHWAY BMP receptor signaling
0.2 3.6 PID ARF 3PATHWAY Arf1 pathway
0.2 3.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 4.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 2.0 PID IL23 PATHWAY IL23-mediated signaling events
0.1 1.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 7.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 4.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 3.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 1.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 2.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 3.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.4 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.7 5.0 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.7 4.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.6 5.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.5 3.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.3 3.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.2 3.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 2.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 4.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.2 3.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 1.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 1.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 2.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 1.7 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 2.4 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.1 1.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.6 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 4.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.8 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 0.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 4.3 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 0.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 1.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.1 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 2.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 6.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 2.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 2.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.8 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 1.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)