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Results for myod1
Z-value: 2.41
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Transcription factors associated with myod1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| myod1 | dr10_dc_chr25_-_30845998_30846012 | 0.90 | 1.5e-06 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of myod1
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr8_-_11191783 Show fit | 8.49 |
ENSDART00000131171
|
unc-45 myosin chaperone B |
|
| chr8_-_985673 Show fit | 7.23 |
ENSDART00000170737
|
SET and MYND domain containing 1b |
|
| chr17_-_124685 Show fit | 7.23 |
ENSDART00000158825
|
actin, alpha, cardiac muscle 1b |
|
| chr7_+_49442972 Show fit | 7.21 |
ENSDART00000019446
|
achaete-scute family bHLH transcription factor 1b |
|
| chr7_+_39131795 Show fit | 6.30 |
ENSDART00000025852
|
troponin I type 2b (skeletal, fast), tandem duplicate 1 |
|
| chr7_+_6517248 Show fit | 5.92 |
ENSDART00000102681
|
purine nucleoside phosphorylase 5a |
|
| chr11_-_5868257 Show fit | 5.84 |
ENSDART00000104360
|
guanidinoacetate N-methyltransferase |
|
| chr8_-_7049946 Show fit | 5.68 |
ENSDART00000045669
ENSDART00000162950 |
keratin 73 |
|
| chr22_+_26543146 Show fit | 5.61 |
|
|
|
| chr21_-_25704662 Show fit | 5.47 |
ENSDART00000101211
|
claudin h |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 12.9 | GO:0045214 | sarcomere organization(GO:0045214) |
| 0.5 | 11.8 | GO:0003009 | skeletal muscle contraction(GO:0003009) |
| 1.0 | 9.2 | GO:0001765 | membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836) |
| 0.2 | 8.5 | GO:0061077 | chaperone-mediated protein folding(GO:0061077) |
| 0.1 | 7.2 | GO:0060047 | heart contraction(GO:0060047) |
| 0.0 | 7.2 | GO:0007268 | chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916) |
| 2.4 | 7.1 | GO:0098528 | skeletal muscle fiber differentiation(GO:0098528) |
| 1.0 | 7.1 | GO:0048769 | sarcomerogenesis(GO:0048769) |
| 1.0 | 6.8 | GO:0061162 | establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339) |
| 0.6 | 6.5 | GO:0033292 | T-tubule organization(GO:0033292) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 25.8 | GO:0031672 | A band(GO:0031672) |
| 0.0 | 16.5 | GO:0005615 | extracellular space(GO:0005615) |
| 0.5 | 15.9 | GO:0005901 | caveola(GO:0005901) plasma membrane raft(GO:0044853) |
| 0.7 | 15.6 | GO:0005861 | troponin complex(GO:0005861) |
| 0.1 | 11.4 | GO:0030424 | axon(GO:0030424) |
| 0.1 | 10.0 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.1 | 8.7 | GO:0005911 | cell-cell junction(GO:0005911) |
| 0.0 | 8.7 | GO:0043235 | receptor complex(GO:0043235) |
| 0.6 | 7.3 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.1 | 6.2 | GO:0005795 | Golgi stack(GO:0005795) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 27.3 | GO:0046983 | protein dimerization activity(GO:0046983) |
| 0.0 | 20.8 | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981) |
| 0.0 | 17.3 | GO:0005198 | structural molecule activity(GO:0005198) |
| 0.1 | 12.9 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.8 | 12.6 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.1 | 12.2 | GO:0050839 | cell adhesion molecule binding(GO:0050839) |
| 0.0 | 10.0 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.0 | 9.5 | GO:0051015 | actin filament binding(GO:0051015) |
| 1.3 | 9.2 | GO:0071253 | connexin binding(GO:0071253) |
| 0.1 | 7.9 | GO:0004879 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 9.0 | PID BMP PATHWAY | BMP receptor signaling |
| 0.5 | 8.6 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.1 | 7.0 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.2 | 4.7 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.1 | 4.4 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.3 | 4.3 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.0 | 3.9 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.2 | 3.6 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.2 | 3.6 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.1 | 3.4 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.8 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.6 | 5.5 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.7 | 5.0 | REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
| 0.7 | 4.9 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 4.8 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.2 | 4.4 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.1 | 4.3 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.2 | 3.9 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.5 | 3.5 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.2 | 3.4 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |