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Results for neurod1

Z-value: 0.81

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Transcription factors associated with neurod1

Gene Symbol Gene ID Gene Info
ENSDARG00000019566 neuronal differentiation 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
neurod1dr10_dc_chr9_-_44493074_444931680.792.8e-04Click!

Activity profile of neurod1 motif

Sorted Z-values of neurod1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of neurod1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr9_-_55204516 2.08

chr22_+_26543146 1.91

chr5_-_36237656 1.68 ENSDART00000032481
creatine kinase, muscle a
chr5_-_28090077 1.67

chr9_-_7695437 1.64 ENSDART00000102715
tubulin, alpha 8 like 3
chr9_+_308260 1.57 ENSDART00000163474
SH3 and cysteine rich domain 3
chr10_+_15819127 1.49 ENSDART00000140511
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr21_+_27346176 1.49 ENSDART00000005682
actinin alpha 3a
chr2_-_21693984 1.32 ENSDART00000171699
hedgehog acyltransferase-like, a
chr1_+_51189343 1.28 ENSDART00000150757
ENSDARG00000096092
chr11_+_24687813 1.27 ENSDART00000131431
sulfatase 2a
chr18_+_30391910 1.26 ENSDART00000158871
Gse1 coiled-coil protein
chr3_-_48865474 1.24 ENSDART00000133036
ELAV like neuron-specific RNA binding protein 3
chr7_+_32451041 1.23 ENSDART00000126565
si:ch211-150g13.3
chr22_+_12327849 1.20 ENSDART00000178678
ENSDARG00000106890
chr9_-_44493074 1.18 ENSDART00000167685
neuronal differentiation 1
chr16_+_46327528 1.18 ENSDART00000040769
nuclear receptor subfamily 2, group F, member 5
chr6_-_15526547 1.17 ENSDART00000038133
tripartite motif containing 63a
chr17_+_27383737 1.16 ENSDART00000156756
ENSDARG00000097369
chr10_-_42032702 1.15

chr10_-_43826919 1.15 ENSDART00000039551
ENSDART00000160786
ENSDART00000099134
myocyte enhancer factor 2ca
chr1_+_51925783 1.14 ENSDART00000167514
ATP-binding cassette, sub-family A (ABC1), member 1A
chr1_-_28241500 1.13 ENSDART00000019770
glycoprotein M6Ba
chr8_+_7340538 1.13 ENSDART00000121708
proprotein convertase subtilisin/kexin type 1 inhibitor, like
chr5_+_36093701 1.12 ENSDART00000019259
deltaB
chr15_+_29153215 1.09 ENSDART00000156799
si:ch211-137a8.4
chr21_-_23710216 1.09 ENSDART00000132570
neural cell adhesion molecule 1a
chr18_+_20504980 1.08 ENSDART00000060295
receptor-associated protein of the synapse, 43kD
chr16_+_46034246 1.08 ENSDART00000101753
myotubularin related protein 11
chr5_-_40133824 1.05 ENSDART00000010896
ISL LIM homeobox 1
chr6_-_43094573 1.05 ENSDART00000084389
leucine rich repeat neuronal 1
chr2_+_2895642 1.03 ENSDART00000032459
aquaporin 1a (Colton blood group), tandem duplicate 1
chr15_+_7179382 1.02 ENSDART00000101578
hairy-related 8.2
chr10_+_4717800 1.01 ENSDART00000161789
paralemmin 2
chr16_+_50189177 1.01 ENSDART00000163565
phospholipase C-like 2
chr4_-_4423059 1.00 ENSDART00000082046
neurotrophin 3
chr16_-_10404109 0.99

chr12_-_41124276 0.99 ENSDART00000172022
ENSDART00000158605
ENSDART00000162967
dihydropyrimidinase-like 4
chr3_-_28120668 0.98

chr22_+_34738389 0.98 ENSDART00000154372
4-hydroxy-2-oxoglutarate aldolase 1
chr23_+_35964754 0.97 ENSDART00000103147
homeobox C12a
chr19_+_34145030 0.97 ENSDART00000151521
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_-_47656197 0.95

chr24_+_7607915 0.95 ENSDART00000124409
caveolae associated protein 1b
chr2_-_30675594 0.95 ENSDART00000087270
catenin (cadherin-associated protein), delta 2b
chr10_+_15819085 0.95 ENSDART00000114483
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr6_-_9964616 0.95

chr5_-_51172369 0.94 ENSDART00000164267
ENSDART00000157866
homer scaffolding protein 1b
chr16_-_37461878 0.94 ENSDART00000142916
si:ch211-208k15.1
chr23_+_21546553 0.93 ENSDART00000142921
si:ch73-21g5.7
chr7_+_28862183 0.92 ENSDART00000052346
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b
chr8_-_11191783 0.92 ENSDART00000131171
unc-45 myosin chaperone B
chr10_+_35344246 0.92 ENSDART00000139229
P450 (cytochrome) oxidoreductase a
chr13_+_25319230 0.91 ENSDART00000101328
atonal bHLH transcription factor 7
chr18_+_23198330 0.91 ENSDART00000143977
myocyte enhancer factor 2aa
chr19_-_34328673 0.90 ENSDART00000164563
engulfment and cell motility 1 (ced-12 homolog, C. elegans)
chr6_+_27156169 0.89 ENSDART00000088364
kinesin family member 1Aa
chr19_+_48499602 0.89

chr6_+_56157608 0.89 ENSDART00000149665
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr5_+_42312784 0.87 ENSDART00000039973
RUN and FYVE domain containing 3
chr16_+_24057260 0.86 ENSDART00000132742
ENSDART00000145330
apolipoprotein C-I
chr23_+_35609887 0.85 ENSDART00000179393
tubulin, alpha 1b
chr2_+_25363717 0.85 ENSDART00000142601
stromal antigen 1a
chr8_-_985673 0.84 ENSDART00000170737
SET and MYND domain containing 1b
chr1_-_37990863 0.83 ENSDART00000132402
glycoprotein M6Ab
chr13_+_28723589 0.83

chr6_-_6835861 0.83 ENSDART00000053304
si:ch211-114n24.6
chr13_+_25298383 0.83

chr7_+_6517248 0.83 ENSDART00000102681
purine nucleoside phosphorylase 5a
chr23_-_1008307 0.82 ENSDART00000110588
cadherin 26, tandem duplicate 1
chr6_-_9329917 0.82 ENSDART00000151470
mitogen-activated protein kinase kinase kinase 2
chr7_-_55406347 0.82 ENSDART00000021009
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr24_+_24924379 0.81 ENSDART00000115165
APC membrane recruitment protein 2
chr21_-_39239757 0.78

chr5_+_37254520 0.78 ENSDART00000051222
preproinsulin
chr9_-_1958795 0.77 ENSDART00000138730
homeobox D3a
chr1_+_9999665 0.76 ENSDART00000054879
ENSDARG00000037679
chr5_-_45729685 0.76 ENSDART00000156577
si:ch211-130m23.5
chr25_-_8475902 0.76 ENSDART00000176751
ENSDARG00000107886
chr24_-_34449257 0.75 ENSDART00000128690
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr13_-_16126849 0.75 ENSDART00000079745
zgc:110045
chr8_-_50159285 0.75 ENSDART00000149010
haptoglobin
chr16_+_24717056 0.75 ENSDART00000157237
si:dkey-56f14.7
chr5_-_33169062 0.74 ENSDART00000133504
DAB2 interacting protein b
chr2_-_42279180 0.74 ENSDART00000047055
tripartite motif containing 55a
chr25_-_28932291 0.74 ENSDART00000073488
ENSDARG00000051805
chr23_-_10242377 0.73 ENSDART00000129044
keratin 5
chr6_-_11544518 0.72 ENSDART00000151195
membrane-associated ring finger (C3HC4) 7
chr23_+_21610798 0.72 ENSDART00000111966
Rho guanine nucleotide exchange factor (GEF) 10-like b
chr5_+_40722565 0.71 ENSDART00000097546
AT rich interactive domain 3C (BRIGHT-like)
chr11_-_32461160 0.71 ENSDART00000155592
protocadherin 17
chr5_+_29327479 0.71

chr8_-_23744125 0.70 ENSDART00000141871
innate immunity activator
chr12_+_30448812 0.69 ENSDART00000126064
si:ch211-28p3.4
chr6_-_60088120 0.69

chr25_-_26292712 0.68 ENSDART00000067114
F-box and leucine-rich repeat protein 22
chr15_+_1832874 0.68 ENSDART00000126253
family with sequence similarity 124B
chr15_+_3296905 0.67 ENSDART00000171723
forkhead box O1 a
chr3_+_17210396 0.67 ENSDART00000090676
si:ch211-210g13.5
chr17_-_52735250 0.66

chr9_+_23854967 0.66 ENSDART00000060905
glycophorin C (Gerbich blood group)
chr10_+_33956052 0.66

chr15_+_15580544 0.66 ENSDART00000016024
tnf receptor-associated factor 4a
chr2_+_50892294 0.65 ENSDART00000018150
ENSDART00000111135
neuronal differentiation 6b
chr3_-_1435654 0.65 ENSDART00000089646
ENSDART00000158110
family with sequence similarity 234, member B
chr10_-_30016761 0.64 ENSDART00000078800
lens intrinsic membrane protein 2.1
chr10_-_15896595 0.64 ENSDART00000092343
tight junction protein 2a (zona occludens 2)
chr11_-_23206021 0.64 ENSDART00000032844
pleckstrin homology domain containing, family A member 6
chr16_-_32059848 0.64 ENSDART00000138701
glutathione S-transferase kappa 1
chr19_-_27676873 0.64 ENSDART00000143919
gamma-aminobutyric acid (GABA) B receptor, 1b
chr8_-_7425677 0.63 ENSDART00000149671
histone deacetylase 6
chr6_-_43094926 0.63 ENSDART00000084389
leucine rich repeat neuronal 1
chr1_-_40587797 0.62 ENSDART00000170895
regulator of G protein signaling 12b
chr5_+_23741791 0.62 ENSDART00000049003
ATPase, H+ transporting, lysosomal, V1 subunit Aa
chr14_+_2969679 0.60 ENSDART00000044678
ENSDARG00000034011
chr3_+_49277125 0.60 ENSDART00000161724
growth arrest-specific 7a
chr24_+_35173816 0.60

chr5_+_29327363 0.59

chr4_-_9591451 0.59 ENSDART00000114060
cerebral dopamine neurotrophic factor
chr15_-_4537178 0.58 ENSDART00000155619
ENSDART00000128602
transcription factor Dp-2
chr18_-_47026460 0.58 ENSDART00000108574
GRAM domain containing 1Bb
chr13_-_24181106 0.58 ENSDART00000004420
RAB4a, member RAS oncogene family
chr11_+_39768718 0.57 ENSDART00000130278
si:dkey-264d12.1
chr16_+_5625301 0.57

chr16_-_33976031 0.57 ENSDART00000110743
dynein, axonemal, light intermediate chain 1
chr25_+_34515221 0.57 ENSDART00000046218
filamin C, gamma a (actin binding protein 280)
chr25_+_7391458 0.57 ENSDART00000042928
fucokinase
chr10_-_28474085 0.57

chr7_+_72128846 0.57 ENSDART00000123887
mitogen-activated protein kinase 8 interacting protein 1
chr21_+_32285006 0.57

chr24_-_38758093 0.56

chr1_+_52308366 0.56 ENSDART00000108492
inositol polyphosphate-4-phosphatase type II B
chr15_+_19358079 0.56 ENSDART00000123815
junctional adhesion molecule 3a
chr17_-_37040941 0.55 ENSDART00000126823
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr11_-_25803101 0.55 ENSDART00000088888
kazrin, periplakin interacting protein b
chr1_-_48853800 0.55 ENSDART00000137357
zgc:175214
chr8_-_14113377 0.55 ENSDART00000090427
si:dkey-6n6.1
chr20_+_35377079 0.54 ENSDART00000168216
family with sequence similarity 49, member A
chr23_-_19053587 0.53

chr8_+_28513670 0.53 ENSDART00000110291
sulfiredoxin 1 homolog (S. cerevisiae)
chr10_-_13220838 0.53 ENSDART00000160265
muscle, skeletal, receptor tyrosine kinase
chr22_+_24131239 0.52 ENSDART00000159165
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr23_-_15381030 0.52

chr8_-_16556749 0.52 ENSDART00000101655
calreticulin
chr19_-_27676807 0.52 ENSDART00000045616
gamma-aminobutyric acid (GABA) B receptor, 1b
chr20_+_23599157 0.52 ENSDART00000149922
palladin, cytoskeletal associated protein
chr23_-_18131105 0.52 ENSDART00000173102
zgc:92287
chr7_-_68629353 0.52

chr20_-_49965171 0.52

chr23_-_15807415 0.52 ENSDART00000178557
ENSDARG00000108083
chr12_+_22137783 0.51 ENSDART00000131175
wingless-type MMTV integration site family, member 3
chr6_+_30441419 0.50

chr18_+_36825511 0.50 ENSDART00000098958
tetratricopeptide repeat domain 9B
chr11_+_36781811 0.50 ENSDART00000109235
bicaudal D homolog 2 (Drosophila)
chr5_+_3172101 0.50 ENSDART00000080486
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1
chr22_-_17026124 0.50 ENSDART00000138382
nuclear factor I/A
chr7_-_14913632 0.49

chr8_-_6899611 0.49 ENSDART00000139545
WD repeat domain 13
chr23_+_37535830 0.49

chr16_+_50189117 0.49 ENSDART00000163565
phospholipase C-like 2
chr6_+_54134129 0.49 ENSDART00000156554
high mobility group AT-hook 1b
chr16_-_51287698 0.48 ENSDART00000156255
argonaute RISC catalytic component 1
chr3_+_26023021 0.48

chr2_-_30005139 0.48 ENSDART00000146968
canopy1
chr1_-_18809429 0.48 ENSDART00000124260
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr1_+_9999842 0.48 ENSDART00000152438
ENSDARG00000037679
chr20_-_49965261 0.48

chr18_-_14868444 0.48 ENSDART00000045232
metastasis suppressor 1-like a
chr5_-_62116975 0.47 ENSDART00000144469
adenosine A2b receptor
chr14_+_6117282 0.47 ENSDART00000051556
ATP-binding cassette, sub-family A (ABC1), member 1B
chr25_-_35539585 0.46 ENSDART00000073432
retinoblastoma-like 2 (p130)
chr3_-_55995924 0.46 ENSDART00000167356
transcription factor AP-4 (activating enhancer binding protein 4)
chr19_+_35415174 0.46 ENSDART00000103266
WDYHV motif containing 1
chr17_-_52493315 0.46 ENSDART00000156806
ribosomal protein S6 kinase-like 1
chr3_+_33209227 0.46 ENSDART00000128786
peptide YYa
chr7_-_29070193 0.46 ENSDART00000147251
transient receptor potential cation channel, subfamily M, member 1a
chr7_+_20215723 0.46 ENSDART00000173724
ENSDART00000173773
si:dkey-33c9.8
chr12_-_3903961 0.45 ENSDART00000134292
ENSDARG00000021154
chr18_+_12179227 0.45 ENSDART00000162067
ENSDART00000168386
FYVE, RhoGEF and PH domain containing 4a
chr18_+_15827187 0.45 ENSDART00000147024
ENSDART00000099944
ENSDART00000160470
nudix (nucleoside diphosphate linked moiety X)-type motif 4a
chr10_+_9134634 0.44 ENSDART00000110443
follistatin b
chr14_-_136402 0.44

chr1_+_11400375 0.44

chr10_-_17383466 0.44

chr1_-_55162455 0.44 ENSDART00000137909
sterile alpha motif domain containing 1b
chr3_-_28120760 0.44

chr5_+_43365449 0.44 ENSDART00000113502
si:dkey-84j12.1
chr3_+_38651644 0.44 ENSDART00000083394
si:dkey-106c17.3
chr5_+_29327447 0.44

chr16_+_5625552 0.43

chr10_-_24401876 0.43 ENSDART00000149362
phosphatidylinositol transfer protein, alpha b
chr25_+_16593169 0.43 ENSDART00000073416
cat eye syndrome chromosome region, candidate 1a
chr9_+_33177527 0.43 ENSDART00000174533
VANGL planar cell polarity protein 1
chr25_-_35159840 0.43 ENSDART00000148718
ENSDART00000164189
ENSDART00000027174
leucine-rich repeat kinase 2
chr3_+_17760847 0.42 ENSDART00000080946
tetratricopeptide repeat domain 25
chr1_+_2074153 0.42 ENSDART00000058877
RAP2A, member of RAS oncogene family b
chr14_-_24304373 0.42

chr12_-_36255806 0.42 ENSDART00000159513
si:dkey-113d16.9
chr19_-_33301572 0.42 ENSDART00000052080
lysosomal protein transmembrane 4 beta
chr22_+_13862110 0.42 ENSDART00000105711
SH3-domain binding protein 4a

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0060254 N-terminal protein palmitoylation(GO:0006500) negative regulation of lipoprotein metabolic process(GO:0050748) regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.4 1.6 GO:0070296 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) sarcoplasmic reticulum calcium ion transport(GO:0070296) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
0.4 1.1 GO:0098810 neurotransmitter uptake(GO:0001504) regulation of neurotransmitter uptake(GO:0051580) neurotransmitter reuptake(GO:0098810)
0.4 1.5 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.3 1.0 GO:0003091 renal water homeostasis(GO:0003091) renal water transport(GO:0003097) carbon dioxide transport(GO:0015670)
0.3 2.0 GO:0032374 regulation of sterol transport(GO:0032371) regulation of cholesterol transport(GO:0032374)
0.3 0.9 GO:1990092 calcium-dependent self proteolysis(GO:1990092)
0.3 1.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.2 1.7 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.2 0.7 GO:0048659 smooth muscle cell proliferation(GO:0048659)
0.2 0.7 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2 1.7 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.2 1.4 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.2 0.8 GO:0030858 positive regulation of epithelial cell differentiation(GO:0030858) regulation of feeding behavior(GO:0060259)
0.2 0.9 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 2.0 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.2 0.3 GO:0097378 interneuron axon guidance(GO:0097376) spinal cord interneuron axon guidance(GO:0097377) dorsal spinal cord interneuron axon guidance(GO:0097378)
0.2 1.0 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.2 1.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.2 0.9 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.1 0.7 GO:0061337 cardiac conduction(GO:0061337)
0.1 0.4 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 0.4 GO:0044036 cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.1 0.7 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 1.4 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 0.5 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.1 1.2 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.1 0.8 GO:0001964 startle response(GO:0001964)
0.1 1.4 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 1.0 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.1 0.4 GO:0045582 positive regulation of T cell differentiation(GO:0045582)
0.1 0.7 GO:0086003 cardiac muscle cell contraction(GO:0086003)
0.1 0.7 GO:0030183 B cell differentiation(GO:0030183)
0.1 0.3 GO:0060296 regulation of cilium beat frequency(GO:0003356) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1 0.3 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.1 0.9 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.5 GO:0033700 phospholipid efflux(GO:0033700)
0.1 0.7 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.4 GO:0009158 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.5 GO:0098508 endothelial to hematopoietic transition(GO:0098508)
0.1 1.4 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 0.6 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.1 0.4 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.1 0.2 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.1 0.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.5 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.5 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.2 GO:0048852 post-embryonic morphogenesis(GO:0009886) post-embryonic foregut morphogenesis(GO:0048618) hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852) adenohypophysis morphogenesis(GO:0048855)
0.0 0.9 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.5 GO:0007631 feeding behavior(GO:0007631)
0.0 0.5 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.9 GO:0071698 olfactory placode development(GO:0071698)
0.0 0.6 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.9 GO:0036269 swimming behavior(GO:0036269)
0.0 0.8 GO:0007398 ectoderm development(GO:0007398)
0.0 0.3 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.3 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.0 0.6 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.1 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.5 GO:0097178 ruffle assembly(GO:0097178)
0.0 1.1 GO:0007416 synapse assembly(GO:0007416)
0.0 0.2 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.6 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.6 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.7 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.6 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 2.0 GO:0042552 myelination(GO:0042552)
0.0 0.1 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.7 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.9 GO:0009225 nucleotide-sugar metabolic process(GO:0009225)
0.0 0.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.4 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.1 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.9 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.1 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.9 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 1.1 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.3 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.8 GO:0051693 regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835) actin filament capping(GO:0051693)
0.0 0.6 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 2.0 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.9 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.0 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.4 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.3 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 1.4 GO:0031101 fin regeneration(GO:0031101)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.6 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.2 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.1 GO:1900044 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.4 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.4 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 2.4 GO:0098916 chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916)
0.0 0.5 GO:0034599 cellular response to oxidative stress(GO:0034599)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.3 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.0 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.4 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 0.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.3 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.6 GO:0006476 protein deacetylation(GO:0006476)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0044295 axonal growth cone(GO:0044295)
0.2 1.2 GO:0038039 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1 0.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.3 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.1 1.6 GO:0030315 T-tubule(GO:0030315)
0.1 0.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.7 GO:0031672 A band(GO:0031672)
0.1 0.3 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.1 0.4 GO:0008091 spectrin(GO:0008091)
0.1 0.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 2.4 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.3 GO:0042583 chromaffin granule(GO:0042583)
0.0 1.9 GO:0014069 postsynaptic density(GO:0014069)
0.0 1.5 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 1.6 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.1 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.0 0.9 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.6 GO:0030175 filopodium(GO:0030175)
0.0 0.3 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0032420 stereocilium(GO:0032420)
0.0 2.3 GO:0030425 dendrite(GO:0030425)
0.0 1.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.4 GO:0045095 keratin filament(GO:0045095)
0.0 0.7 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.4 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.2 GO:0043195 terminal bouton(GO:0043195)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0099738 basal cortex(GO:0045180) cell cortex region(GO:0099738)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.8 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.7 GO:0098802 plasma membrane receptor complex(GO:0098802)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.3 1.0 GO:0015166 polyol transmembrane transporter activity(GO:0015166) glycerol transmembrane transporter activity(GO:0015168)
0.3 1.6 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 0.9 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.2 1.5 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2 1.7 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.2 0.6 GO:0047611 acetylspermidine deacetylase activity(GO:0047611)
0.2 0.8 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.2 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 1.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 0.9 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.2 0.9 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.2 2.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 1.0 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.2 1.1 GO:0043495 protein anchor(GO:0043495)
0.1 1.0 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.8 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.8 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 0.4 GO:0003796 lysozyme activity(GO:0003796)
0.1 1.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.9 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.1 0.9 GO:0031852 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.7 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 0.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.2 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.1 0.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 0.9 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.4 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 3.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.5 GO:0034452 dynactin binding(GO:0034452)
0.1 1.1 GO:0005112 Notch binding(GO:0005112)
0.1 0.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.1 2.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.2 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 0.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.5 GO:0016405 CoA-ligase activity(GO:0016405)
0.0 0.4 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.4 GO:0048185 activin binding(GO:0048185)
0.0 0.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 2.3 GO:0045296 cadherin binding(GO:0045296)
0.0 0.5 GO:0005518 collagen binding(GO:0005518)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.9 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.3 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.9 GO:0005179 hormone activity(GO:0005179)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.5 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.1 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.5 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.4 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.5 GO:0019955 cytokine binding(GO:0019955)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0016881 acid-amino acid ligase activity(GO:0016881)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 1.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 0.9 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.8 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.6 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 1.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.9 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.9 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.0 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.7 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation