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Results for nfatc2a

Z-value: 3.16

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Transcription factors associated with nfatc2a

Gene Symbol Gene ID Gene Info
ENSDARG00000100927 nuclear factor of activated T cells 2a

Activity profile of nfatc2a motif

Sorted Z-values of nfatc2a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of nfatc2a

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_-_39315024 10.82 ENSDART00000012644
keratin 4
chr24_-_28814066 7.99 ENSDART00000042065
ENSDART00000170675
ENSDART00000158668
collagen, type XI, alpha 1a
chr16_-_45943282 7.41 ENSDART00000133213
antifreeze protein type IV
chr20_+_12559243 7.13 ENSDART00000172370
si:dkey-269i1.4
chr17_+_8166167 6.81 ENSDART00000169900
CDC42 binding protein kinase alpha (DMPK-like) a
chr20_-_49880744 6.38 ENSDART00000025926
collagen, type XII, alpha 1b
chr3_+_24067387 6.17 ENSDART00000055609
activating transcription factor 4b
chr4_+_2215426 5.99 ENSDART00000168370
fibroblast growth factor receptor substrate 2a
chr5_+_28559915 5.86 ENSDART00000088827
dipeptidyl-peptidase 7
chr5_-_30324182 5.85 ENSDART00000153909
spinster homolog 2 (Drosophila)
chr22_-_26333957 5.73 ENSDART00000130493
calpain 2, (m/II) large subunit b
chr1_-_50831155 5.52 ENSDART00000152719
sprouty-related, EVH1 domain containing 2a
chr19_-_41482388 5.43 ENSDART00000111982
sarcoglycan, epsilon
chr4_+_7668939 5.31 ENSDART00000149218
ELK3, ETS-domain protein
chr4_+_10065500 4.95 ENSDART00000026492
filamin C, gamma b (actin binding protein 280)
chr16_+_23482744 4.95 ENSDART00000148961
S100 calcium binding protein A10b
chr21_-_5852663 4.73 ENSDART00000130521
calcium channel flower domain containing 1
chr19_+_9054095 4.57 ENSDART00000039597
cellular retinoic acid binding protein 2, b
chr2_-_34010299 4.55 ENSDART00000140910
patched 2
chr18_+_38773971 4.43 ENSDART00000010177
one cut homeobox 1
chr1_-_674449 4.38 ENSDART00000160564
cysteine/tyrosine-rich 1
chr14_-_30363703 4.34 ENSDART00000134098
EGF containing fibulin-like extracellular matrix protein 2a
chr22_+_31089813 4.34 ENSDART00000060005
ribosomal protein L32
chr7_+_21455138 4.34 ENSDART00000173992
lysine (K)-specific demethylase 6B, a
chr23_+_36002332 4.32 ENSDART00000103139
homeobox C8a
chr13_-_30515486 4.28 ENSDART00000139607
zinc finger, CCHC domain containing 24
chr13_+_22545318 4.21 ENSDART00000143312
zgc:193505
chr8_+_46651079 4.20 ENSDART00000113803
hairy-related 3
chr9_+_30279907 4.20 ENSDART00000102981
collagen, type VIII, alpha 1a
chr3_+_26013873 4.19 ENSDART00000043932
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr6_-_47842137 4.16 ENSDART00000141986
leucine-rich repeats and immunoglobulin-like domains 2
chr7_-_54407681 4.13 ENSDART00000162795
cyclin D1
chr11_-_38843219 4.11 ENSDART00000102827
prolyl 3-hydroxylase 1
chr16_-_14506846 4.06 ENSDART00000170957
cellular retinoic acid binding protein 2, a
chr12_-_3098744 4.00 ENSDART00000015092
collagen, type I, alpha 1b
chr23_+_32573474 3.96 ENSDART00000134811
si:dkey-261h17.1
chr21_+_5528438 3.95 ENSDART00000168158
shroom family member 3
chr22_-_35967525 3.93 ENSDART00000176971
ENSDARG00000106725
chr9_-_9693163 3.87 ENSDART00000018228
glycogen synthase kinase 3 beta
chr9_-_13383818 3.86 ENSDART00000084055
frizzled class receptor 7a
chr11_-_26428979 3.83 ENSDART00000111539
EF-hand and coiled-coil domain containing 1
chr4_+_1667305 3.82 ENSDART00000150198
solute carrier family 38, member 4
chr1_-_53746151 3.81 ENSDART00000179565
ENSDARG00000108130
chr6_-_49527428 3.73 ENSDART00000128025
ribosomal protein S26, like
chr3_-_23444371 3.69 ENSDART00000087726
insulin-like growth factor 2 mRNA binding protein 1
chr15_+_34131126 3.68 ENSDART00000169487
von Willebrand factor D and EGF domains
chr10_+_4717800 3.64 ENSDART00000161789
paralemmin 2
chr8_-_38357549 3.62 ENSDART00000129597
sorbin and SH3 domain containing 3
chr7_+_38479571 3.62 ENSDART00000170486
coagulation factor II (thrombin)
chr16_+_29558320 3.61 ENSDART00000011497
cathepsin K
chr15_+_125263 3.54

chr6_-_48095609 3.51 ENSDART00000137458
solute carrier family 2 (facilitated glucose transporter), member 1b
chr5_-_58162552 3.49 ENSDART00000161230
Rho guanine nucleotide exchange factor (GEF) 12b
chr24_-_9151388 3.49 ENSDART00000149875
TGFB-induced factor homeobox 1
chr2_-_21265803 3.44 ENSDART00000006870
prostaglandin-endoperoxide synthase 2a
chr18_+_40364675 3.43 ENSDART00000098791
ENSDART00000049171
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr24_-_33869817 3.40 ENSDART00000079283
transmembrane protein with EGF-like and two follistatin-like domains 1b
chr2_-_43998886 3.38 ENSDART00000146493
zinc finger E-box binding homeobox 1a
chr12_-_25796463 3.38 ENSDART00000152983
si:dkey-193p11.2
chr23_+_23730717 3.36

chr4_-_17066886 3.36 ENSDART00000134595
SRY (sex determining region Y)-box 5
KN150405v1_-_65814 3.34 ENSDART00000160124
ENSDARG00000100753
chr17_-_35934175 3.32 ENSDART00000110040
ENSDART00000137525
SRY (sex determining region Y)-box 11a
ENSDARG00000092907
chr12_+_25509394 3.31 ENSDART00000077157
SIX homeobox 3b
chr12_-_1442400 3.31

chr16_-_36022327 3.28 ENSDART00000172252
eva-1 homolog Ba (C. elegans)
chr5_-_14148028 3.28 ENSDART00000113037
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr20_-_25063937 3.27 ENSDART00000159122
eph receptor A7
chr13_-_5440923 3.25 ENSDART00000102576
Meis homeobox 1 b
chr13_+_7575753 3.24

chr1_+_49894978 3.24 ENSDART00000020412
polycystic kidney disease 2
chr23_+_23559246 3.23 ENSDART00000172214
agrin
chr23_+_33362843 3.22

chr19_+_41924878 3.22 ENSDART00000172311
si:ch211-57n23.1
chr2_+_23139845 3.21 ENSDART00000042255
RAB6B, member RAS oncogene family b
chr3_+_36146072 3.20 ENSDART00000148444
zgc:86896
chr4_-_16556116 3.17 ENSDART00000033188
B-cell translocation gene 1, anti-proliferative
chr2_-_42384993 3.17 ENSDART00000141358
apolipoprotein M
chr9_-_34129128 3.16

chr7_+_22386456 3.16 ENSDART00000146081
plac8 onzin related protein 5
chr16_-_22797736 3.13 ENSDART00000143836
si:ch211-105c13.3
chr23_-_26798851 3.07 ENSDART00000170576
ENSDART00000166123
heparan sulfate proteoglycan 2
chr7_-_54407461 3.06 ENSDART00000162795
cyclin D1
chr4_+_22959458 3.04 ENSDART00000036531
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr14_-_24094142 3.04 ENSDART00000126894
family with sequence similarity 13, member B
chr4_+_14361566 3.02 ENSDART00000007103
NUAK family, SNF1-like kinase, 1a
chr21_-_3301751 3.01 ENSDART00000009740
SMAD family member 7
chr13_-_42630425 3.00 ENSDART00000161950
calpain 2, (m/II) large subunit a
chr4_+_14972481 2.99 ENSDART00000005985
smoothened, frizzled class receptor
chr12_-_1442655 2.98

chr3_-_49242655 2.98 ENSDART00000142200
ENSDART00000139524
ADP-ribosylation factor-like 16
chr1_-_35196892 2.97 ENSDART00000033566
SMAD family member 1
chr24_-_23175007 2.97 ENSDART00000112256
zinc finger homeobox 4
chr6_+_58921655 2.96 ENSDART00000083628
DNA-damage-inducible transcript 3
chr5_-_68270398 2.95 ENSDART00000161561
ENSDARG00000059093
chr1_-_46047321 2.93

chr13_+_25298383 2.92

chr12_+_40919018 2.92 ENSDART00000176047
ENSDARG00000108020
chr17_-_30846176 2.88 ENSDART00000062811
YY1 transcription factor a
chr8_+_47861033 2.87 ENSDART00000147159
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a
chr4_+_14361655 2.86 ENSDART00000007103
NUAK family, SNF1-like kinase, 1a
chr6_-_39315608 2.85 ENSDART00000012644
keratin 4
chr18_+_29424354 2.85 ENSDART00000014703
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a)
chr1_-_29669484 2.83 ENSDART00000164202
insulin-like growth factor 2 mRNA binding protein 2b
chr20_+_13998066 2.83 ENSDART00000007744
solute carrier family 30 (zinc transporter), member 1a
chr17_+_52736192 2.82 ENSDART00000158273
ENSDART00000161414
Meis homeobox 2a
chr9_-_14533551 2.80 ENSDART00000056103
neuropilin 2b
chr1_+_29054033 2.80 ENSDART00000054066
zic family member 2 (odd-paired homolog, Drosophila) b
chr3_+_30790513 2.80 ENSDART00000130422
claudin i
chr16_+_21098948 2.79 ENSDART00000006043
homeobox A11b
chr20_-_34389652 2.78 ENSDART00000144705
ENSDART00000020389
hemicentin 1
chr19_+_5375413 2.77 ENSDART00000141237
si:dkeyp-113d7.10
chr18_-_15404998 2.74 ENSDART00000031752
regulatory factor X, 4
chr7_+_34417030 2.73 ENSDART00000108473
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr24_+_7832020 2.72 ENSDART00000019705
bone morphogenetic protein 6
chr10_-_43924675 2.72 ENSDART00000052307
arrestin domain containing 3b
chr21_+_7844259 2.71 ENSDART00000027268
orthopedia homeobox a
chr9_-_33584190 2.71 ENSDART00000138844
calcium/calmodulin-dependent serine protein kinase a
chr18_-_46260401 2.70 ENSDART00000153930
si:dkey-244a7.1
chr3_-_34363698 2.70

chr15_-_11257445 2.69

chr7_-_56493164 2.69

chr11_-_22438900 2.69 ENSDART00000014062
myogenin
chr21_-_23074223 2.68 ENSDART00000147896
ubiquitin specific peptidase 28
chr13_-_3022033 2.67 ENSDART00000050934
protein kinase domain containing, cytoplasmic a
chr9_-_24183317 2.67 ENSDART00000140346
collagen, type VI, alpha 3
chr23_-_18972097 2.66 ENSDART00000133826
ENSDARG00000057403
chr16_-_13734068 2.65 ENSDART00000164344
si:dkeyp-69b9.6
chr20_-_47521258 2.65

chr12_+_18112818 2.64 ENSDART00000130741
family with sequence similarity 20, member Cb
chr25_+_558191 2.64 ENSDART00000126863
ENSDART00000166012
neural EGFL like 2a
chr24_-_23174888 2.63 ENSDART00000112256
zinc finger homeobox 4
chr16_-_13733759 2.63 ENSDART00000164344
si:dkeyp-69b9.6
chr17_-_52735250 2.63

chr18_-_14723138 2.63 ENSDART00000010129
peptide deformylase (mitochondrial)
chr5_-_71340996 2.62 ENSDART00000162526
SET and MYND domain containing 1a
chr11_+_37639045 2.62 ENSDART00000111157
si:ch211-112f3.4
chr20_+_26639029 2.62 ENSDART00000045397
syntaxin 11b, tandem duplicate 1
chr23_-_3466041 2.61 ENSDART00000002309
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba
chr20_+_29731714 2.59 ENSDART00000101556
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2b
chr22_-_23238714 2.58 ENSDART00000054807
LIM homeobox 9
chr9_-_1958795 2.58 ENSDART00000138730
homeobox D3a
chr7_-_41347831 2.58 ENSDART00000174304
plexin domain containing 2
chr7_+_73598802 2.57 ENSDART00000109720
zgc:163061
chr8_-_40287789 2.57 ENSDART00000074125
apelin receptor a
chr25_+_31053243 2.56 ENSDART00000067039
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8a
chr4_+_7668691 2.55 ENSDART00000149218
ELK3, ETS-domain protein
chr16_+_39396358 2.55

KN149795v1_-_24393 2.54

chr15_-_27778111 2.53 ENSDART00000134373
LIM homeobox 1a
chr20_+_34423970 2.53 ENSDART00000061659
influenza virus NS1A binding protein a
chr1_-_55554518 2.52 ENSDART00000019573
zgc:65894
chr7_+_30516734 2.52 ENSDART00000174000
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr14_+_23980348 2.51 ENSDART00000160984
ENSDARG00000105465
chr23_-_18958008 2.51 ENSDART00000133419
ENSDARG00000057403
chr3_-_32464649 2.50 ENSDART00000103239
tetraspanin 4b
chr20_+_34640226 2.50 ENSDART00000076946
ENSDARG00000054723
chr21_-_11539798 2.49 ENSDART00000144770
calpastatin
chr6_-_59510397 2.47 ENSDART00000170685
GLI family zinc finger 1
chr7_+_39130411 2.46 ENSDART00000144750
troponin I type 2b (skeletal, fast), tandem duplicate 1
chr6_-_27901354 2.46 ENSDART00000155116
im:7152348
chr9_-_9864049 2.45 ENSDART00000121456
follistatin-like 1b
chr22_+_2921305 2.44 ENSDART00000143258
centrosomal protein 19
chr2_+_25363717 2.44 ENSDART00000142601
stromal antigen 1a
chr14_+_6122948 2.43 ENSDART00000149783
ENSDART00000148461
ATP-binding cassette, sub-family A (ABC1), member 1B
chr2_+_3701942 2.42 ENSDART00000132572
glutamic pyruvate transaminase (alanine aminotransferase) 2, like
chr2_-_30071872 2.41 ENSDART00000056747
sonic hedgehog b
chr7_+_25794014 2.40 ENSDART00000174010
ENSDART00000173815
ENSDARG00000105638
chr6_-_39053400 2.39 ENSDART00000165839
tensin 2b
chr23_-_19789409 2.39 ENSDART00000131860
ribosomal protein L10
chr6_-_49527616 2.38 ENSDART00000128025
ribosomal protein S26, like
chr18_-_22297945 2.37

chr11_+_24687813 2.37 ENSDART00000131431
sulfatase 2a
chr7_-_33080261 2.36 ENSDART00000114041
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr4_+_18974767 2.36 ENSDART00000066973
IMP (inosine 5'-monophosphate) dehydrogenase 1b
chr5_+_32739678 2.36 ENSDART00000026085
prostaglandin E synthase
chr1_-_46015367 2.36 ENSDART00000074519
karyopherin alpha 3 (importin alpha 4)
chr19_+_7798512 2.35 ENSDART00000104719
ENSDART00000146747
tuftelin 1b
chr13_+_27102308 2.34 ENSDART00000145901
Ras and Rab interactor 2
chr7_-_33678058 2.34 ENSDART00000173513
protein inhibitor of activated STAT, 1a
chr2_-_30071993 2.33 ENSDART00000056747
sonic hedgehog b
chr6_+_49096966 2.32 ENSDART00000141042
ENSDART00000143369
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr13_+_28364942 2.32 ENSDART00000025583
fibroblast growth factor 8a
chr1_-_10201135 2.32 ENSDART00000131744
dystrophin
chr1_-_45709828 2.31 ENSDART00000150029
ATPase, class VI, type 11A
chr1_-_10822278 2.30 ENSDART00000091205
sidekick cell adhesion molecule 1b
chr1_-_44888989 2.30 ENSDART00000135089
activating transcription factor 7 interacting protein
chr6_+_43018443 2.30 ENSDART00000064888
T-cell leukemia translocation altered gene
chr16_-_35633520 2.30 ENSDART00000169868
ENSDART00000166606
sex comb on midleg homolog 1 (Drosophila)
chr11_-_23151247 2.29

chr3_-_58170499 2.29 ENSDART00000074272
im:6904045
chr12_-_25973094 2.29 ENSDART00000171206
ENSDART00000171212
ENSDART00000170265
LIM domain binding 3b
chr11_-_33355651 2.29 ENSDART00000033980
LIM and senescent cell antigen-like domains 1
chr17_-_20124053 2.27 ENSDART00000133327
actinin, alpha 2b
chr9_-_12604530 2.26 ENSDART00000128931
insulin-like growth factor 2 mRNA binding protein 2a
chr2_+_27739201 2.26 ENSDART00000145909
selenoprotein P, plasma, 1b
chr5_+_34397578 2.26 ENSDART00000043341
forkhead box D1
chr15_+_7179382 2.25 ENSDART00000101578
hairy-related 8.2
chr25_-_31452381 2.25 ENSDART00000028338
secretory carrier membrane protein 5a
chr21_+_25651712 2.25 ENSDART00000135123
si:dkey-17e16.17

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0097377 interneuron axon guidance(GO:0097376) spinal cord interneuron axon guidance(GO:0097377) dorsal spinal cord interneuron axon guidance(GO:0097378)
1.7 5.1 GO:0021742 abducens nucleus development(GO:0021742)
1.6 8.2 GO:0048745 smooth muscle tissue development(GO:0048745)
1.5 5.9 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
1.4 4.2 GO:0097702 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246) response to oscillatory fluid shear stress(GO:0097702) cellular response to oscillatory fluid shear stress(GO:0097704)
1.4 4.2 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
1.4 4.2 GO:0045933 regulation of skeletal muscle contraction(GO:0014819) positive regulation of muscle contraction(GO:0045933)
1.3 4.0 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
1.3 5.3 GO:0030194 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
1.3 6.6 GO:1902751 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) mitotic G1 DNA damage checkpoint(GO:0031571) positive regulation of cell cycle G2/M phase transition(GO:1902751)
1.2 5.0 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
1.1 3.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
1.1 4.4 GO:0061194 tongue development(GO:0043586) tongue morphogenesis(GO:0043587) taste bud development(GO:0061193) taste bud morphogenesis(GO:0061194) taste bud formation(GO:0061195)
1.0 5.1 GO:0048635 negative regulation of muscle organ development(GO:0048635)
1.0 3.0 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
1.0 4.8 GO:0035988 chondrocyte proliferation(GO:0035988)
0.9 2.8 GO:1990359 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.9 3.7 GO:1901741 positive regulation of syncytium formation by plasma membrane fusion(GO:0060143) positive regulation of myoblast fusion(GO:1901741)
0.9 5.4 GO:0014831 gastro-intestinal system smooth muscle contraction(GO:0014831)
0.9 2.6 GO:0070166 enamel mineralization(GO:0070166) amelogenesis(GO:0097186)
0.9 4.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.7 4.5 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.7 6.4 GO:0060956 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.7 4.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.7 2.8 GO:0010226 response to lithium ion(GO:0010226)
0.7 2.7 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.7 2.0 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.7 5.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.6 1.9 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
0.6 1.9 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.6 15.5 GO:0048385 regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.6 4.4 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.6 2.5 GO:0036363 transforming growth factor beta activation(GO:0036363) transforming growth factor beta production(GO:0071604) regulation of transforming growth factor beta production(GO:0071634) negative regulation of transforming growth factor beta production(GO:0071635) regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
0.6 11.1 GO:0032963 collagen metabolic process(GO:0032963) multicellular organismal macromolecule metabolic process(GO:0044259)
0.6 9.8 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.6 2.4 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.6 1.8 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.6 4.2 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.6 3.6 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.6 2.3 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.5 1.1 GO:1990402 embryonic liver development(GO:1990402)
0.5 2.2 GO:0048853 forebrain morphogenesis(GO:0048853)
0.5 1.6 GO:0015822 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.5 2.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.5 2.6 GO:0002030 inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of calcium ion transport into cytosol(GO:0010524) positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) regulation of inhibitory G-protein coupled receptor phosphorylation(GO:1904323) positive regulation of inhibitory G-protein coupled receptor phosphorylation(GO:1904325)
0.5 1.5 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.5 2.0 GO:0031643 positive regulation of myelination(GO:0031643)
0.5 2.0 GO:1903726 negative regulation of phospholipid metabolic process(GO:1903726)
0.5 5.7 GO:0021767 mammillary body development(GO:0021767)
0.5 1.4 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.5 1.8 GO:1901490 regulation of lymphangiogenesis(GO:1901490) positive regulation of lymphangiogenesis(GO:1901492)
0.4 2.2 GO:0030308 negative regulation of cell growth(GO:0030308)
0.4 2.7 GO:0016203 muscle attachment(GO:0016203)
0.4 0.9 GO:0045168 cell-cell signaling involved in cell fate commitment(GO:0045168)
0.4 1.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.4 7.4 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.4 1.3 GO:0061032 visceral serous pericardium development(GO:0061032)
0.4 1.2 GO:0097037 heme export(GO:0097037)
0.4 3.1 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.4 0.8 GO:0030852 regulation of granulocyte differentiation(GO:0030852) regulation of neutrophil differentiation(GO:0045658)
0.4 1.5 GO:0002832 negative regulation of response to biotic stimulus(GO:0002832) negative regulation of defense response to virus(GO:0050687)
0.4 2.6 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.4 5.2 GO:0014028 notochord formation(GO:0014028)
0.4 1.5 GO:0016199 axon midline choice point recognition(GO:0016199)
0.4 1.1 GO:0010265 SCF complex assembly(GO:0010265)
0.4 1.4 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.3 2.4 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.3 3.8 GO:0030316 osteoclast differentiation(GO:0030316)
0.3 1.7 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.3 1.4 GO:0099558 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.3 2.4 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.3 5.7 GO:0071711 basement membrane organization(GO:0071711)
0.3 1.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.3 1.6 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.3 2.6 GO:0034389 lipid particle organization(GO:0034389)
0.3 1.0 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.3 3.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.3 2.2 GO:0045444 fat cell differentiation(GO:0045444)
0.3 2.8 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.3 3.0 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.3 3.3 GO:0006183 GTP biosynthetic process(GO:0006183)
0.3 1.5 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.3 0.9 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
0.3 2.4 GO:0097028 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011) dendritic cell differentiation(GO:0097028)
0.3 1.2 GO:1901998 toxin transport(GO:1901998)
0.3 3.1 GO:0033292 T-tubule organization(GO:0033292)
0.3 2.5 GO:0021794 thalamus development(GO:0021794)
0.3 2.2 GO:0033700 phospholipid efflux(GO:0033700)
0.3 1.1 GO:0021576 hindbrain formation(GO:0021576)
0.3 2.5 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.3 3.3 GO:0070654 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.3 1.9 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.3 1.3 GO:0090104 pancreatic epsilon cell differentiation(GO:0090104)
0.3 3.0 GO:0015671 oxygen transport(GO:0015671)
0.3 6.7 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.3 0.8 GO:0072045 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341) convergent extension involved in nephron morphogenesis(GO:0072045)
0.3 3.5 GO:0015701 bicarbonate transport(GO:0015701)
0.3 7.6 GO:0060030 dorsal convergence(GO:0060030)
0.3 2.6 GO:0030241 skeletal muscle thin filament assembly(GO:0030240) skeletal muscle myosin thick filament assembly(GO:0030241)
0.3 1.0 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.3 1.8 GO:0061615 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.3 16.2 GO:0045665 negative regulation of neuron differentiation(GO:0045665)
0.3 1.5 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.2 1.2 GO:0099640 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971) axo-dendritic protein transport(GO:0099640)
0.2 1.0 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 1.7 GO:0060841 venous blood vessel development(GO:0060841)
0.2 0.7 GO:0009215 deoxyribonucleoside triphosphate biosynthetic process(GO:0009202) purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.2 3.2 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2 2.1 GO:0021592 fourth ventricle development(GO:0021592)
0.2 0.7 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.2 2.9 GO:1900052 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.2 0.7 GO:0030803 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclic nucleotide metabolic process(GO:0030800) negative regulation of cyclic nucleotide biosynthetic process(GO:0030803) negative regulation of nucleotide biosynthetic process(GO:0030809) negative regulation of cAMP metabolic process(GO:0030815) negative regulation of cAMP biosynthetic process(GO:0030818) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350) negative regulation of purine nucleotide biosynthetic process(GO:1900372)
0.2 3.9 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.2 2.2 GO:0006956 complement activation(GO:0006956)
0.2 6.2 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.2 1.9 GO:0006527 arginine catabolic process(GO:0006527)
0.2 5.1 GO:0009612 response to mechanical stimulus(GO:0009612)
0.2 1.0 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.2 0.6 GO:0044806 multicellular organism aging(GO:0010259) G-quadruplex DNA unwinding(GO:0044806)
0.2 1.6 GO:0001964 startle response(GO:0001964)
0.2 8.2 GO:0045214 sarcomere organization(GO:0045214)
0.2 1.0 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 2.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 1.4 GO:0061074 regulation of neural retina development(GO:0061074)
0.2 2.3 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.2 4.5 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.2 2.1 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.2 0.8 GO:0046636 negative regulation of alpha-beta T cell activation(GO:0046636) negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.2 1.7 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.2 0.7 GO:0046888 negative regulation of hormone secretion(GO:0046888)
0.2 0.7 GO:0035776 pronephric proximal tubule development(GO:0035776)
0.2 0.7 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.2 0.4 GO:1990709 presynaptic active zone organization(GO:1990709)
0.2 1.2 GO:0070527 platelet aggregation(GO:0070527)
0.2 2.6 GO:0050654 chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.2 1.4 GO:0060114 vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.2 3.8 GO:0043113 receptor clustering(GO:0043113)
0.2 0.9 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.2 1.0 GO:0035094 response to nicotine(GO:0035094)
0.2 1.4 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.2 0.8 GO:0051031 tRNA transport(GO:0051031)
0.2 1.2 GO:0060416 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.2 1.0 GO:0051601 exocyst localization(GO:0051601)
0.2 1.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.2 12.9 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.2 2.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 0.8 GO:0042987 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.2 1.1 GO:1990089 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.2 1.1 GO:0097475 motor neuron migration(GO:0097475)
0.2 2.6 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.2 0.5 GO:0042214 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247) regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.2 1.2 GO:0051013 microtubule severing(GO:0051013)
0.2 3.3 GO:0016925 protein sumoylation(GO:0016925)
0.2 2.0 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.7 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 1.9 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 2.6 GO:0001819 positive regulation of cytokine production(GO:0001819)
0.1 1.6 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 1.2 GO:0050919 negative chemotaxis(GO:0050919)
0.1 1.9 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.3 GO:0061011 hepatic duct development(GO:0061011)
0.1 3.6 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.1 1.4 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 3.8 GO:0036303 lymph vessel morphogenesis(GO:0036303)
0.1 0.4 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.7 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 1.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 1.0 GO:0048570 notochord morphogenesis(GO:0048570)
0.1 2.5 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.9 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.1 0.4 GO:0010586 miRNA metabolic process(GO:0010586)
0.1 1.6 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 6.9 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.1 2.6 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 1.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 1.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 0.3 GO:0072506 cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320) cellular phosphate ion homeostasis(GO:0030643) phosphate ion homeostasis(GO:0055062) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502) trivalent inorganic anion homeostasis(GO:0072506)
0.1 5.1 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.1 0.9 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 0.6 GO:0001881 receptor recycling(GO:0001881)
0.1 0.6 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 4.7 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.1 0.4 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 1.8 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 0.6 GO:0016559 peroxisome fission(GO:0016559)
0.1 0.1 GO:0046113 nucleobase catabolic process(GO:0046113)
0.1 1.4 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.7 GO:0006959 humoral immune response(GO:0006959)
0.1 4.0 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 0.4 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.1 2.4 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 3.0 GO:0030318 melanocyte differentiation(GO:0030318)
0.1 1.2 GO:0032438 melanosome organization(GO:0032438)
0.1 1.0 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.1 1.8 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 0.5 GO:0030183 B cell differentiation(GO:0030183)
0.1 0.7 GO:0031638 zymogen activation(GO:0031638)
0.1 1.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 2.3 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.5 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.1 1.5 GO:0006826 iron ion transport(GO:0006826)
0.1 1.2 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.9 GO:0060324 face development(GO:0060324)
0.1 1.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.2 GO:0035066 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1 1.4 GO:0021854 limbic system development(GO:0021761) hypothalamus development(GO:0021854)
0.1 0.8 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 1.5 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 1.2 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 1.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.1 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.1 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 1.1 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.1 1.0 GO:0001649 osteoblast differentiation(GO:0001649)
0.1 1.7 GO:0007416 synapse assembly(GO:0007416)
0.1 1.6 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.1 0.9 GO:0003146 heart jogging(GO:0003146)
0.1 1.9 GO:0048484 enteric nervous system development(GO:0048484)
0.1 1.0 GO:0048546 digestive tract morphogenesis(GO:0048546)
0.1 0.5 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 9.9 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.1 0.6 GO:0097320 membrane tubulation(GO:0097320)
0.1 0.4 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.8 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.1 1.9 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.1 1.8 GO:0006836 neurotransmitter transport(GO:0006836)
0.1 1.6 GO:2000181 negative regulation of blood vessel morphogenesis(GO:2000181)
0.1 2.2 GO:0022904 respiratory electron transport chain(GO:0022904)
0.1 1.3 GO:0001570 vasculogenesis(GO:0001570)
0.1 0.4 GO:0010888 negative regulation of cholesterol storage(GO:0010887) negative regulation of lipid storage(GO:0010888)
0.1 1.1 GO:0047496 vesicle transport along microtubule(GO:0047496)
0.1 2.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.9 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.0 0.3 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 1.3 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.8 GO:0030282 bone mineralization(GO:0030282)
0.0 0.7 GO:0021510 spinal cord development(GO:0021510)
0.0 0.6 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.3 GO:0097061 dendritic spine morphogenesis(GO:0060997) dendritic spine organization(GO:0097061)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.2 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.7 GO:0051180 vitamin transport(GO:0051180)
0.0 0.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.4 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 1.0 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.7 GO:0046033 AMP metabolic process(GO:0046033)
0.0 4.5 GO:0050767 regulation of neurogenesis(GO:0050767)
0.0 0.2 GO:0072530 purine-containing compound transmembrane transport(GO:0072530)
0.0 1.5 GO:0048747 muscle fiber development(GO:0048747)
0.0 2.6 GO:0007268 chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916)
0.0 0.5 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.4 GO:0006555 methionine metabolic process(GO:0006555) methionine biosynthetic process(GO:0009086)
0.0 0.8 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.5 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.3 GO:0046660 female sex differentiation(GO:0046660)
0.0 2.0 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 0.3 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.0 0.8 GO:0051262 protein tetramerization(GO:0051262)
0.0 0.5 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 2.0 GO:0030155 regulation of cell adhesion(GO:0030155)
0.0 2.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.7 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.5 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.5 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.2 GO:0010165 response to X-ray(GO:0010165)
0.0 0.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.4 GO:0042407 cristae formation(GO:0042407)
0.0 0.4 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.0 GO:0009791 post-embryonic development(GO:0009791)
0.0 0.9 GO:2001056 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043280) positive regulation of cysteine-type endopeptidase activity(GO:2001056)
0.0 0.7 GO:0006821 chloride transport(GO:0006821)
0.0 1.3 GO:0097485 axon guidance(GO:0007411) neuron projection guidance(GO:0097485)
0.0 0.5 GO:0051607 defense response to virus(GO:0051607)
0.0 0.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.1 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0045899 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.4 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.2 GO:0043666 regulation of phosphatase activity(GO:0010921) regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 1.2 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.3 GO:0002183 cytoplasmic translational initiation(GO:0002183)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.5 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
1.1 6.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.7 2.8 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.7 2.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.6 35.0 GO:0005581 collagen trimer(GO:0005581)
0.6 1.9 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.6 2.5 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.6 4.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.6 7.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.5 12.1 GO:0045095 keratin filament(GO:0045095)
0.5 3.7 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.4 1.2 GO:0070195 growth hormone receptor complex(GO:0070195)
0.4 7.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.3 1.0 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.3 3.7 GO:0014704 intercalated disc(GO:0014704)
0.3 4.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.3 5.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.3 4.0 GO:0043195 terminal bouton(GO:0043195)
0.3 2.9 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.3 1.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 2.6 GO:0031430 M band(GO:0031430)
0.2 2.6 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 0.9 GO:1902636 kinociliary basal body(GO:1902636)
0.2 11.3 GO:0042641 actomyosin(GO:0042641)
0.2 1.7 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.2 1.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.2 2.6 GO:0008278 cohesin complex(GO:0008278)
0.2 6.0 GO:0008305 integrin complex(GO:0008305)
0.2 3.0 GO:0031594 neuromuscular junction(GO:0031594)
0.2 1.4 GO:0072487 MSL complex(GO:0072487)
0.2 1.7 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2 6.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 9.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 8.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 1.1 GO:0038039 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.2 1.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 1.9 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.2 0.8 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.2 0.8 GO:0032420 stereocilium(GO:0032420)
0.2 22.5 GO:0031012 extracellular matrix(GO:0031012)
0.1 1.3 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 6.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 1.5 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 2.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 4.5 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 1.7 GO:0097546 ciliary base(GO:0097546)
0.1 63.7 GO:0005615 extracellular space(GO:0005615)
0.1 1.8 GO:0044545 NSL complex(GO:0044545)
0.1 0.8 GO:0005833 hemoglobin complex(GO:0005833) haptoglobin-hemoglobin complex(GO:0031838)
0.1 3.1 GO:0034707 chloride channel complex(GO:0034707)
0.1 2.5 GO:0005861 troponin complex(GO:0005861)
0.1 1.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.9 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.6 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 3.2 GO:0030426 growth cone(GO:0030426)
0.1 1.2 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.4 GO:0030897 HOPS complex(GO:0030897)
0.1 0.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.5 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.8 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.4 GO:0043679 axon terminus(GO:0043679) neuron projection terminus(GO:0044306)
0.1 1.5 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.8 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 1.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 3.3 GO:0031674 I band(GO:0031674)
0.1 0.2 GO:0043034 costamere(GO:0043034)
0.1 1.5 GO:0043204 perikaryon(GO:0043204)
0.1 3.7 GO:0016324 apical plasma membrane(GO:0016324)
0.1 7.8 GO:0009986 cell surface(GO:0009986)
0.1 1.5 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 0.9 GO:0030175 filopodium(GO:0030175)
0.1 3.9 GO:0000922 spindle pole(GO:0000922)
0.1 1.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.3 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.7 GO:0070847 core mediator complex(GO:0070847)
0.1 5.7 GO:0000786 nucleosome(GO:0000786)
0.1 5.1 GO:0030425 dendrite(GO:0030425)
0.1 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 2.4 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 7.4 GO:0043235 receptor complex(GO:0043235)
0.0 0.1 GO:0031526 brush border membrane(GO:0031526)
0.0 1.0 GO:0060076 postsynaptic density(GO:0014069) excitatory synapse(GO:0060076)
0.0 0.7 GO:0030686 90S preribosome(GO:0030686)
0.0 1.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0089701 U2AF(GO:0089701)
0.0 9.8 GO:0005576 extracellular region(GO:0005576)
0.0 0.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.6 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.6 GO:0030027 lamellipodium(GO:0030027)
0.0 1.7 GO:0005776 autophagosome(GO:0005776)
0.0 1.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 3.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.0 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 0.5 GO:0030684 preribosome(GO:0030684)
0.0 0.8 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.9 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.5 GO:0030496 midbody(GO:0030496)
0.0 0.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 6.6 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.4 GO:0031519 PcG protein complex(GO:0031519)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.4 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
1.2 4.9 GO:0008142 oxysterol binding(GO:0008142)
1.2 4.8 GO:0008158 hedgehog receptor activity(GO:0008158)
1.1 3.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.9 2.8 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.9 7.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.9 4.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.8 6.4 GO:0005113 patched binding(GO:0005113)
0.7 7.9 GO:0001972 retinoic acid binding(GO:0001972)
0.7 2.1 GO:0070699 beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
0.7 10.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.7 5.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.6 5.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.6 1.7 GO:0048406 nerve growth factor binding(GO:0048406)
0.6 1.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.6 2.8 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.6 1.7 GO:0015057 thrombin receptor activity(GO:0015057)
0.6 7.8 GO:0070411 I-SMAD binding(GO:0070411)
0.5 1.6 GO:0034417 bisphosphoglycerate 3-phosphatase activity(GO:0034417)
0.5 1.6 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.5 1.6 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.5 9.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.5 1.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.5 3.5 GO:0015145 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.5 2.0 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.5 7.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.5 2.4 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.5 2.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.4 1.8 GO:0043121 neurotrophin binding(GO:0043121)
0.4 26.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.4 2.6 GO:0060182 apelin receptor activity(GO:0060182)
0.4 1.3 GO:0004925 prolactin receptor activity(GO:0004925)
0.4 2.5 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.4 4.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.4 1.2 GO:0004903 growth hormone receptor activity(GO:0004903)
0.4 2.2 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.4 1.1 GO:0004953 icosanoid receptor activity(GO:0004953)
0.4 2.2 GO:0048039 ubiquinone binding(GO:0048039)
0.4 3.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.3 1.0 GO:0070548 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360) L-glutamine aminotransferase activity(GO:0070548)
0.3 4.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.3 1.3 GO:0045503 dynein light chain binding(GO:0045503)
0.3 2.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.3 2.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.3 1.9 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.3 1.2 GO:0030274 LIM domain binding(GO:0030274)
0.3 2.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.3 1.5 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.3 0.9 GO:0070644 vitamin D response element binding(GO:0070644)
0.3 2.5 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.3 3.0 GO:0005344 oxygen transporter activity(GO:0005344) oxygen binding(GO:0019825)
0.3 1.6 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.3 3.7 GO:0038191 neuropilin binding(GO:0038191)
0.3 0.8 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.3 4.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 1.8 GO:0070095 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.2 1.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 0.7 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.2 4.0 GO:0043236 laminin binding(GO:0043236)
0.2 3.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.2 1.4 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.2 0.9 GO:0030507 spectrin binding(GO:0030507)
0.2 1.1 GO:0008506 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 2.7 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.2 8.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 1.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 1.0 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.2 1.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2 1.0 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 2.6 GO:0005080 protein kinase C binding(GO:0005080)
0.2 0.7 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.2 1.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.2 1.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 2.9 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.2 1.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 2.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.4 GO:0017046 peptide hormone binding(GO:0017046)
0.2 1.5 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 0.7 GO:0099528 G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.2 2.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 3.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 1.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 0.5 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.2 13.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 0.8 GO:0017040 ceramidase activity(GO:0017040)
0.2 1.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.2 2.3 GO:0005518 collagen binding(GO:0005518)
0.1 2.4 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.4 GO:0001729 ceramide kinase activity(GO:0001729)
0.1 9.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 11.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 1.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 1.3 GO:0016405 CoA-ligase activity(GO:0016405)
0.1 0.7 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.2 GO:0048495 Roundabout binding(GO:0048495)
0.1 2.3 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 1.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 15.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 1.4 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 1.0 GO:0005522 profilin binding(GO:0005522)
0.1 1.1 GO:0005272 sodium channel activity(GO:0005272)
0.1 1.0 GO:0070700 BMP receptor binding(GO:0070700)
0.1 1.0 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 0.9 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 3.0 GO:0005178 integrin binding(GO:0005178)
0.1 1.2 GO:0015232 heme transporter activity(GO:0015232)
0.1 1.0 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 2.9 GO:0019003 GDP binding(GO:0019003)
0.1 1.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 4.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 17.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 108.8 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 0.3 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.1 0.7 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.4 GO:0010181 FMN binding(GO:0010181)
0.1 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.4 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 0.6 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 1.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.3 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.5 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 1.5 GO:0098632 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.1 7.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 2.7 GO:0005109 frizzled binding(GO:0005109)
0.1 0.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.8 GO:0008201 heparin binding(GO:0008201)
0.1 0.5 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 1.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.0 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.4 GO:0031628 opioid receptor binding(GO:0031628)
0.1 1.0 GO:0008483 transaminase activity(GO:0008483)
0.1 15.9 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.1 2.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.3 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.1 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 0.9 GO:0019843 rRNA binding(GO:0019843)
0.1 0.9 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.1 0.8 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 1.5 GO:0019955 cytokine binding(GO:0019955)
0.0 0.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.3 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.4 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 5.0 GO:1990837 sequence-specific double-stranded DNA binding(GO:1990837)
0.0 2.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 21.9 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 2.0 GO:0051287 NAD binding(GO:0051287)
0.0 2.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 2.3 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.7 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 1.4 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725) molybdenum ion binding(GO:0030151)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.3 GO:0005048 signal sequence binding(GO:0005048)
0.0 0.5 GO:0004175 endopeptidase activity(GO:0004175)
0.0 0.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.7 GO:0005126 cytokine receptor binding(GO:0005126)
0.0 0.7 GO:0009055 electron carrier activity(GO:0009055)
0.0 1.8 GO:0005216 ion channel activity(GO:0005216)
0.0 0.5 GO:0003777 microtubule motor activity(GO:0003777)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 17.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.6 6.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.6 3.0 PID ALK2 PATHWAY ALK2 signaling events
0.6 4.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.6 1.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.5 10.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.4 1.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.4 2.5 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.3 1.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 4.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.3 3.0 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.2 3.0 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.2 9.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 16.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 2.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 1.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.2 3.9 PID BMP PATHWAY BMP receptor signaling
0.1 3.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 0.5 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 0.8 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 4.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 1.9 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 4.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.8 PID AP1 PATHWAY AP-1 transcription factor network
0.1 4.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 3.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 1.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 0.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 1.7 PID LKB1 PATHWAY LKB1 signaling events
0.1 1.5 PID ARF 3PATHWAY Arf1 pathway
0.1 0.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.1 PID CMYB PATHWAY C-MYB transcription factor network
0.1 0.5 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.1 1.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 2.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.1 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.1 PID ATM PATHWAY ATM pathway
0.0 1.0 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.5 PID P73PATHWAY p73 transcription factor network
0.0 0.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.1 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.7 3.6 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.6 3.0 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.5 2.2 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.4 3.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.4 3.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.4 6.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.4 1.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.4 3.0 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.4 7.3 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.4 2.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.4 1.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.3 7.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.3 3.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.3 1.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3 11.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.3 1.9 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.3 3.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 4.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.3 6.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.2 1.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 1.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 1.9 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 6.1 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.2 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 1.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 7.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 2.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.2 3.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 4.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.0 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 0.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 11.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.8 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.1 0.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.5 REACTOME SHC MEDIATED CASCADE Genes involved in SHC-mediated cascade
0.1 0.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 1.6 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 1.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 0.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 4.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.1 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.6 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 0.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 5.2 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 2.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 0.9 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 1.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 3.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.2 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 1.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.5 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC