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Results for nkx2.2b

Z-value: 1.03

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Transcription factors associated with nkx2.2b

Gene Symbol Gene ID Gene Info
nkx2.2b
ENSDARG00000101549 NK2 homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx2.2bdr10_dc_chr20_+_48950833_48950877-0.371.6e-01Click!

Activity profile of nkx2.2b motif

Sorted Z-values of nkx2.2b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx2.2b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr19_-_24971633 2.08 ENSDART00000162801
polr3gla
polymerase (RNA) III (DNA directed) polypeptide G like a
chr23_-_6831711 1.95 ENSDART00000125393
FP102169.1
ENSDARG00000089210
chr1_+_15875513 1.94

chr1_-_46141359 1.67 ENSDART00000142406
si:ch73-160h15.3
si:ch73-160h15.3
chr2_-_53797472 1.66 ENSDART00000057053
im:7138239
im:7138239
chr12_+_29121368 1.58 ENSDART00000006505
mxtx2
mix-type homeobox gene 2
chr14_-_10311891 1.56 ENSDART00000136649
si:dkey-92i17.2
si:dkey-92i17.2
chr12_-_22279843 1.44 ENSDART00000153194
si:dkey-38p12.3
si:dkey-38p12.3
chr14_+_23420053 1.36 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr4_+_828545 1.34 ENSDART00000067461
si:ch211-152c2.3
si:ch211-152c2.3
chr13_+_33578737 1.29 ENSDART00000161465
CABZ01087953.1
ENSDARG00000104106
chr5_-_30114979 1.21 ENSDART00000016758
ftr82
finTRIM family, member 82
chr23_-_24468191 1.13 ENSDART00000044918
epha2b
eph receptor A2 b
chr23_-_24468290 1.10 ENSDART00000044918
epha2b
eph receptor A2 b
chr8_+_26273354 1.10 ENSDART00000053463
mgll
monoglyceride lipase
chr2_-_53797503 1.04 ENSDART00000057053
im:7138239
im:7138239
chr3_-_27516974 1.04 ENSDART00000151675
si:ch211-157c3.4
si:ch211-157c3.4
chr18_-_35432838 0.96 ENSDART00000141703
snrpa
small nuclear ribonucleoprotein polypeptide A
chr9_-_18903879 0.96 ENSDART00000138785
si:dkey-239h2.3
si:dkey-239h2.3
chr7_+_22386456 0.88 ENSDART00000146081
ponzr5
plac8 onzin related protein 5
chr25_-_14472107 0.88

chr3_+_28450576 0.87 ENSDART00000150893
sept12
septin 12
chr15_-_5912236 0.83

chr22_+_866803 0.82 ENSDART00000140588
stk38b
serine/threonine kinase 38b
chr13_+_8509344 0.79 ENSDART00000140489
epcam
epithelial cell adhesion molecule
chr12_-_10438255 0.74 ENSDART00000106172
rac1a
ras-related C3 botulinum toxin substrate 1a (rho family, small GTP binding protein Rac1)
chr12_+_30119447 0.68 ENSDART00000102081
afap1l2
actin filament associated protein 1-like 2
chr21_+_130546 0.68 ENSDART00000174654
ARSB
arylsulfatase B
chr10_+_33758581 0.68 ENSDART00000141650
b3glctb
beta 3-glucosyltransferase b
chr12_-_28680035 0.67 ENSDART00000020667
osbpl7
oxysterol binding protein-like 7
chr9_-_20743808 0.66

chr5_-_30115110 0.64 ENSDART00000016758
ftr82
finTRIM family, member 82
chr19_-_5142209 0.64 ENSDART00000150980
chd4a
chromodomain helicase DNA binding protein 4a
chr7_-_22519196 0.64 ENSDART00000129919
ENSDARG00000091111
ENSDARG00000091111
chr11_-_25019298 0.64 ENSDART00000130477
ENSDART00000079578
snai1a
snail family zinc finger 1a
chr16_-_2642235 0.64

chr2_+_37441802 0.63 ENSDART00000132427
phc3
polyhomeotic homolog 3 (Drosophila)
chr24_+_9898743 0.63 ENSDART00000144186
pou6f2
POU class 6 homeobox 2
chr12_-_9400272 0.63 ENSDART00000003932
erbb2
erb-b2 receptor tyrosine kinase 2
chr13_+_45387478 0.63 ENSDART00000019113
tmem57b
transmembrane protein 57b
chr18_-_3430278 0.63 ENSDART00000157669
capn5a
calpain 5a
chr6_-_45867149 0.61 ENSDART00000062459
rbm19
RNA binding motif protein 19
chr2_+_49343278 0.61 ENSDART00000175147
sema6ba
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba
chr23_+_36608246 0.60 ENSDART00000113179
tspan31
tetraspanin 31
chr5_-_24013767 0.59 ENSDART00000003957
tia1l
cytotoxic granule-associated RNA binding protein 1, like
chr18_+_17503828 0.59 ENSDART00000161827
si:dkey-102f14.5
si:dkey-102f14.5
chr19_-_5141645 0.58 ENSDART00000150980
chd4a
chromodomain helicase DNA binding protein 4a
chr14_+_24543399 0.58 ENSDART00000106039
arhgef37
Rho guanine nucleotide exchange factor (GEF) 37
chr13_+_8508786 0.58 ENSDART00000059321
epcam
epithelial cell adhesion molecule
chr11_+_24919694 0.58 ENSDART00000162618
ENSDART00000128126
trpc4apa
transient receptor potential cation channel, subfamily C, member 4 associated protein a
chr7_+_22386328 0.58 ENSDART00000141048
ponzr5
plac8 onzin related protein 5
chr15_-_5912917 0.57

chr6_-_26904787 0.57 ENSDART00000134259
hdlbpa
high density lipoprotein binding protein a
chr8_-_38284904 0.56 ENSDART00000125920
pdlim2
PDZ and LIM domain 2 (mystique)
chr19_-_5142009 0.55 ENSDART00000150980
chd4a
chromodomain helicase DNA binding protein 4a
chr5_+_60028622 0.55

chr7_+_26457055 0.55

chr12_-_4264663 0.54 ENSDART00000152521
ca15b
carbonic anhydrase XVb
chr8_-_38284748 0.54 ENSDART00000102233
pdlim2
PDZ and LIM domain 2 (mystique)
chr4_+_6024067 0.53

chr3_-_26830876 0.53

chr12_-_28679813 0.53 ENSDART00000020667
osbpl7
oxysterol binding protein-like 7
chr1_+_29919378 0.52 ENSDART00000127670
bora
bora, aurora kinase A activator
chr16_+_39292206 0.52 ENSDART00000127319
ENSDART00000102510
zgc:77056
zgc:77056
chr21_+_130849 0.52

chr7_-_71343686 0.51 ENSDART00000128678
mettl4
methyltransferase like 4
chr16_-_4780901 0.51 ENSDART00000029485
arnt
aryl hydrocarbon receptor nuclear translocator
chr8_+_47737851 0.50 ENSDART00000160166
si:ch211-243p7.3
si:ch211-243p7.3
chr12_-_22279890 0.50 ENSDART00000153194
si:dkey-38p12.3
si:dkey-38p12.3
chr18_-_27334059 0.49 ENSDART00000028294
zgc:56106
zgc:56106
chr10_+_45138195 0.48 ENSDART00000162566
h2afvb
H2A histone family, member Vb
chr25_-_4294947 0.48

chr4_+_46379457 0.48 ENSDART00000162948
BX324155.1
ENSDARG00000104638
chr4_+_2215426 0.48 ENSDART00000168370
frs2a
fibroblast growth factor receptor substrate 2a
chr7_-_17129072 0.48

chr19_-_5142238 0.48 ENSDART00000130062
chd4a
chromodomain helicase DNA binding protein 4a
chr22_-_22234380 0.47 ENSDART00000020937
hdgfrp2
hepatoma-derived growth factor-related protein 2
chr5_-_18941045 0.47 ENSDART00000141268
kctd10
potassium channel tetramerization domain containing 10
chr5_-_12086593 0.46 ENSDART00000081494
ENSDART00000162780
vsig10
V-set and immunoglobulin domain containing 10
chr22_+_11745592 0.46 ENSDART00000140272
krt96
keratin 96
chr3_+_60299938 0.46 ENSDART00000053482
tsen54
TSEN54 tRNA splicing endonuclease subunit
chr5_-_66820811 0.46 ENSDART00000128050
ENSDARG00000042520
ENSDARG00000042520
chr18_-_22745979 0.46 ENSDART00000023721
nudt21
nudix hydrolase 21
chr14_+_23419864 0.46 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr3_+_24004141 0.45 ENSDART00000155216
si:ch211-246i5.5
si:ch211-246i5.5
chr22_-_20695416 0.45 ENSDART00000105532
oaz1a
ornithine decarboxylase antizyme 1a
chr2_-_53797678 0.45 ENSDART00000057053
im:7138239
im:7138239
chr20_+_52021000 0.45 ENSDART00000074330
taf1a
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A
chr24_-_32607801 0.45 ENSDART00000143781
EIF1B
eukaryotic translation initiation factor 1B
chr18_-_7522421 0.45 ENSDART00000101292
si:dkey-238c7.16
si:dkey-238c7.16
chr24_+_14516577 0.44

chr1_-_358810 0.44 ENSDART00000098627
pros1
protein S (alpha)
chr22_-_22234261 0.43 ENSDART00000113824
ENSDART00000169594
ENSDART00000158261
hdgfrp2
hepatoma-derived growth factor-related protein 2
chr6_-_22869821 0.43 ENSDART00000167674
mif4gda
MIF4G domain containing a
chr4_-_26046562 0.43 ENSDART00000124514
usp44
ubiquitin specific peptidase 44
chr20_+_53563189 0.43 ENSDART00000060432
cdc40
cell division cycle 40 homolog (S. cerevisiae)
chr14_-_23811519 0.42 ENSDART00000124255
cpeb4a
cytoplasmic polyadenylation element binding protein 4a
chr8_+_52456064 0.42 ENSDART00000012758
zgc:77112
zgc:77112
chr18_-_14723138 0.42 ENSDART00000010129
pdf
peptide deformylase (mitochondrial)
chr3_-_9755642 0.41 ENSDART00000168366
crebbpb
CREB binding protein b
chr24_+_35297193 0.41 ENSDART00000075142
ENSDART00000158801
pcmtd1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr22_-_25015224 0.41 ENSDART00000015512
polr3f
polymerase (RNA) III (DNA directed) polypeptide F
chr20_-_40357302 0.41

chr4_-_20119812 0.41 ENSDART00000100867
fam3c
family with sequence similarity 3, member C
chr18_-_22745846 0.41 ENSDART00000023721
nudt21
nudix hydrolase 21
chr3_+_19490148 0.40

chr23_+_38314255 0.40 ENSDART00000129593
znf217
zinc finger protein 217
chr12_-_22279713 0.40 ENSDART00000153194
si:dkey-38p12.3
si:dkey-38p12.3
chr7_-_37816600 0.40 ENSDART00000052366
cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr15_+_25516764 0.40 ENSDART00000009545
pak4
p21 protein (Cdc42/Rac)-activated kinase 4
chr7_-_26246798 0.40 ENSDART00000058913
eif4a1a
eukaryotic translation initiation factor 4A1A
chr16_-_21277161 0.40

chr16_-_41718971 0.40

chr8_-_25055333 0.39 ENSDART00000134190
sort1b
sortilin 1b
chr5_+_60028657 0.39

chr16_-_25485248 0.38 ENSDART00000040756
zgc:136493
zgc:136493
chr6_+_28215039 0.38 ENSDART00000104394
smx5
smx5
chr5_+_40543353 0.37 ENSDART00000011229
sub1b
SUB1 homolog, transcriptional regulator b
chr8_-_24269848 0.37

chr8_-_49739908 0.37 ENSDART00000138810
gkap1
G kinase anchoring protein 1
chr8_-_38284959 0.37 ENSDART00000125920
pdlim2
PDZ and LIM domain 2 (mystique)
chr10_-_25383262 0.36 ENSDART00000166348
cct8
chaperonin containing TCP1, subunit 8 (theta)
chr20_-_40357240 0.36

chr12_-_25058837 0.36 ENSDART00000135368
rhoq
ras homolog family member Q
chr23_+_38313746 0.35 ENSDART00000129593
znf217
zinc finger protein 217
chr6_+_12849673 0.35 ENSDART00000172158
l3hypdh
trans-L-3-hydroxyproline dehydratase
chr8_-_38284660 0.34 ENSDART00000102233
pdlim2
PDZ and LIM domain 2 (mystique)
chr22_+_866633 0.33 ENSDART00000140588
stk38b
serine/threonine kinase 38b
chr5_-_12086676 0.33 ENSDART00000081494
ENSDART00000162780
vsig10
V-set and immunoglobulin domain containing 10
chr8_-_38285034 0.33 ENSDART00000125920
pdlim2
PDZ and LIM domain 2 (mystique)
chr21_-_13654658 0.32 ENSDART00000111666
npdc1a
neural proliferation, differentiation and control, 1a
chr23_-_12305794 0.32

chr11_+_3240975 0.32 ENSDART00000082458
sarnp
SAP domain containing ribonucleoprotein
chr24_-_34794538 0.32 ENSDART00000171009
ENSDART00000170046
ctnna1
catenin (cadherin-associated protein), alpha 1
chr11_-_25019899 0.32 ENSDART00000123567
snai1a
snail family zinc finger 1a
chr22_+_35156074 0.32 ENSDART00000130581
rnf13
ring finger protein 13
chr20_+_53563389 0.32 ENSDART00000060432
cdc40
cell division cycle 40 homolog (S. cerevisiae)
chr16_-_4781028 0.31 ENSDART00000029485
arnt
aryl hydrocarbon receptor nuclear translocator
chr8_+_3372903 0.31 ENSDART00000017850
ctu1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr7_-_5252575 0.31

chr16_-_21277108 0.31

chr5_+_40543392 0.30 ENSDART00000011229
sub1b
SUB1 homolog, transcriptional regulator b
chr3_-_19913032 0.30

chr16_-_33151404 0.30 ENSDART00000145055
pnrc2
proline-rich nuclear receptor coactivator 2
chr14_-_10065562 0.30 ENSDART00000003879
fam199x
family with sequence similarity 199, X-linked
chr14_+_23419894 0.30 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr16_-_11908084 0.29 ENSDART00000135408
cnfn
cornifelin
chr5_+_69178270 0.29 ENSDART00000097359
dnajc25
DnaJ (Hsp40) homolog, subfamily C , member 25
chr13_+_36469737 0.29 ENSDART00000164545
cnih1
cornichon family AMPA receptor auxiliary protein 1
chr19_-_33264349 0.29

chr15_+_24628191 0.29 ENSDART00000140658
dhrs13b
dehydrogenase/reductase (SDR family) member 13b
chr3_+_18657831 0.29 ENSDART00000055757
tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr16_-_21277206 0.28

chr8_-_25055160 0.28 ENSDART00000134190
sort1b
sortilin 1b
chr2_-_22875246 0.28 ENSDART00000159641
znf644a
zinc finger protein 644a
chr6_-_39220951 0.28 ENSDART00000133305
ENSDART00000166290
os9
osteosarcoma amplified 9, endoplasmic reticulum lectin
chr22_-_7412566 0.28 ENSDART00000161615
ENSDART00000158210
BX511034.5
ENSDARG00000099295
chr4_+_74885660 0.28 ENSDART00000164709
zgc:153116
zgc:153116
chr7_-_71343519 0.28 ENSDART00000128678
mettl4
methyltransferase like 4
chr13_-_22568419 0.28 ENSDART00000165617
glud1a
glutamate dehydrogenase 1a
chr24_+_41448854 0.28

chr21_-_36934378 0.27 ENSDART00000065208
nop16
NOP16 nucleolar protein homolog (yeast)
chr3_+_4058776 0.27

chr2_-_15656155 0.27 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr14_-_38532734 0.27 ENSDART00000133442
gsr
glutathione reductase
chr22_+_21292537 0.27 ENSDART00000132605
shc2
SHC (Src homology 2 domain containing) transforming protein 2
chr9_-_14302452 0.27 ENSDART00000135458
abcb6b
ATP-binding cassette, sub-family B (MDR/TAP), member 6b
chr5_-_56533970 0.27 ENSDART00000171252
man2a1
mannosidase, alpha, class 2A, member 1
chr12_-_22387786 0.26 ENSDART00000109707
neurl4
neuralized E3 ubiquitin protein ligase 4
chr20_-_34742647 0.26

chr7_-_11436543 0.26

KN150423v1_-_9882 0.26

chr5_-_55243980 0.26 ENSDART00000014049
wdr36
WD repeat domain 36
chr13_-_33186976 0.25 ENSDART00000136701
tmem234
transmembrane protein 234
chr20_+_32853879 0.25 ENSDART00000023006
fam84a
family with sequence similarity 84, member A
chr17_+_10592507 0.25 ENSDART00000097274
ATG14
autophagy related 14
chr6_-_57542175 0.25 ENSDART00000156967
itcha
itchy E3 ubiquitin protein ligase a
chr19_-_21192796 0.25 ENSDART00000019206
ngly1
N-glycanase 1
chr19_-_1977399 0.25

chr9_-_10026818 0.25 ENSDART00000124423
ugt1ab
UDP glucuronosyltransferase 1 family a, b
chr3_+_19536018 0.25 ENSDART00000006490
tlk2
tousled-like kinase 2
chr19_-_35380449 0.24

chr7_-_11436576 0.24

chr6_-_49548896 0.24 ENSDART00000169678
ppp4r1l
protein phosphatase 4, regulatory subunit 1-like
chr4_+_67023074 0.24 ENSDART00000158749
zgc:173702
zgc:173702
chr19_+_31280451 0.24 ENSDART00000047461
mfsd2ab
major facilitator superfamily domain containing 2ab
chr12_+_23691397 0.24 ENSDART00000066331
svila
supervillin a
chr23_+_1069029 0.24 ENSDART00000159263
slc34a2b
solute carrier family 34 (type II sodium/phosphate cotransporter), member 2b
chr11_+_24919823 0.24 ENSDART00000162618
ENSDART00000128126
trpc4apa
transient receptor potential cation channel, subfamily C, member 4 associated protein a
chr1_-_46430811 0.23 ENSDART00000048445
mhc1zea
major histocompatibility complex class I ZEA
chr6_-_12967003 0.23

chr21_+_27303969 0.23 ENSDART00000146724
dpp3
dipeptidyl-peptidase 3
chr2_+_3125365 0.23 ENSDART00000164308
ENSDART00000167649
pik3r3a
phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
chr12_+_30611399 0.22 ENSDART00000153036
slc35f3a
solute carrier family 35, member F3a
chr25_-_18910254 0.22 ENSDART00000019765
efcab6
EF-hand calcium binding domain 6
chr11_+_18710724 0.22 ENSDART00000176141
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr7_-_13661739 0.22 ENSDART00000062257
slc39a1
solute carrier family 39 (zinc transporter), member 1
chr23_-_15090815 0.22 ENSDART00000147636
ndrg3b
ndrg family member 3b
chr15_-_1928150 0.22

chr2_-_32404106 0.22 ENSDART00000148202
ubtfl
upstream binding transcription factor, like

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0031439 pro-B cell differentiation(GO:0002328) regulation of mRNA cleavage(GO:0031437) positive regulation of mRNA cleavage(GO:0031439) regulation of pro-B cell differentiation(GO:2000973) positive regulation of pro-B cell differentiation(GO:2000975)
0.2 0.6 GO:0048913 anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.2 0.6 GO:0032635 interleukin-6 production(GO:0032635) regulation of interleukin-6 production(GO:0032675)
0.1 0.4 GO:0042730 fibrinolysis(GO:0042730)
0.1 0.5 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.4 GO:0002931 response to ischemia(GO:0002931)
0.1 0.3 GO:0006538 glutamate catabolic process(GO:0006538)
0.1 0.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 2.3 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.2 GO:0030320 cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320) cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.2 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.7 GO:2000144 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 0.4 GO:1904666 regulation of ubiquitin protein ligase activity(GO:1904666)
0.1 2.1 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.1 0.4 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 0.2 GO:0051977 lysophospholipid transport(GO:0051977) lipid transport across blood brain barrier(GO:1990379)
0.1 0.8 GO:1902622 regulation of neutrophil migration(GO:1902622)
0.0 1.0 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.1 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.3 GO:1903513 endoplasmic reticulum to cytosol transport(GO:1903513)
0.0 0.4 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 0.3 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 1.4 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 0.6 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.4 GO:0090316 positive regulation of intracellular protein transport(GO:0090316)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.8 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.5 GO:0008354 germ cell migration(GO:0008354)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 1.6 GO:0001706 endoderm formation(GO:0001706)
0.0 0.7 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.8 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.1 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 2.2 GO:0031101 fin regeneration(GO:0031101)
0.0 0.1 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.0 0.4 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 0.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.1 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677) detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.5 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.2 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 2.7 GO:0033674 positive regulation of kinase activity(GO:0033674)
0.0 0.6 GO:0048546 digestive tract morphogenesis(GO:0048546)
0.0 0.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.1 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.0 0.5 GO:0048854 brain morphogenesis(GO:0048854)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.3 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.4 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.8 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0042382 paraspeckles(GO:0042382)
0.2 0.5 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.4 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 1.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 2.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 2.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.3 GO:0002144 cytosolic tRNA wobble base thiouridylase complex(GO:0002144)
0.1 0.4 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 2.2 GO:0031941 filamentous actin(GO:0031941)
0.1 0.8 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 1.0 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.8 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.9 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0005903 brush border(GO:0005903)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 1.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.7 GO:0005844 polysome(GO:0005844)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.7 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.7 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0050699 WW domain binding(GO:0050699)
0.2 1.0 GO:0051059 NF-kappaB binding(GO:0051059)
0.2 2.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.6 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.0 GO:0030619 U1 snRNA binding(GO:0030619)
0.1 2.2 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.3 GO:0016639 glutamate dehydrogenase (NAD+) activity(GO:0004352) glutamate dehydrogenase [NAD(P)+] activity(GO:0004353) oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 0.9 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.5 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 2.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.3 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.1 1.2 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.2 GO:0051978 lysophospholipid transporter activity(GO:0051978)
0.0 0.1 GO:0008311 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.8 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.4 GO:2001069 glycogen binding(GO:2001069)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.1 GO:0016803 ether hydrolase activity(GO:0016803)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.4 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.7 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.2 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.6 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.8 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.1 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.1 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation