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Results for nkx2.4a+nkx2.4b

Z-value: 0.86

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Transcription factors associated with nkx2.4a+nkx2.4b

Gene Symbol Gene ID Gene Info
nkx2.4a
ENSDARG00000075107 NK2 homeobox 4a
nkx2.4b
ENSDARG00000104107 NK2 homeobox 4b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx2.4adr10_dc_chr17_-_42108276_421083740.821.1e-04Click!
nkx2.4bdr10_dc_chr20_+_48971948_489719820.811.6e-04Click!

Activity profile of nkx2.4a+nkx2.4b motif

Sorted Z-values of nkx2.4a+nkx2.4b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx2.4a+nkx2.4b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr13_-_13163676 2.12 ENSDART00000125883
ENSDART00000013534
fgfr3
fibroblast growth factor receptor 3
chr2_+_42874975 2.09 ENSDART00000075392
basp1
brain abundant, membrane attached signal protein 1
chr14_-_26238386 1.91 ENSDART00000105933
tgfbi
transforming growth factor, beta-induced
chr7_+_25052543 1.89 ENSDART00000110347
cyp26b1
cytochrome P450, family 26, subfamily b, polypeptide 1
chr1_+_25005968 1.84 ENSDART00000054228
lrata
lecithin retinol acyltransferase a (phosphatidylcholine-retinol O-acyltransferase)
chr8_+_23464087 1.76 ENSDART00000026316
sema3gb
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
chr10_-_10059864 1.63 ENSDART00000132375
strbp
spermatid perinuclear RNA binding protein
chr10_+_44364117 1.63

chr19_-_23037220 1.59 ENSDART00000090669
pleca
plectin a
chr25_-_27399421 1.52 ENSDART00000156906
asb15a
ankyrin repeat and SOCS box containing 15a
chr17_+_27417635 1.49 ENSDART00000052446
vgll2b
vestigial-like family member 2b
chr10_+_21850059 1.46 ENSDART00000164634
ENSDART00000172513
pcdh1g32
protocadherin 1 gamma 32
chr16_+_22950567 1.42 ENSDART00000143957
flad1
flavin adenine dinucleotide synthetase 1
chr5_+_36010448 1.38 ENSDART00000097684
nova1
neuro-oncological ventral antigen 1
chr8_-_49356479 1.38 ENSDART00000053203
plp2
proteolipid protein 2
chr13_-_13163801 1.36 ENSDART00000156968
fgfr3
fibroblast growth factor receptor 3
chr14_+_13919450 1.26 ENSDART00000174760
nlgn3a
neuroligin 3a
chr23_+_14058972 1.23 ENSDART00000090864
lmod3
leiomodin 3 (fetal)
chr5_-_33225263 1.16 ENSDART00000139371
BX005445.1
ENSDARG00000095064
chr24_+_30343717 1.15 ENSDART00000162377
FP085414.1
ENSDARG00000100270
chr14_-_32877752 1.14 ENSDART00000163046
si:dkey-31j3.11
si:dkey-31j3.11
chr22_+_12746080 1.13 ENSDART00000044683
ftcd
formimidoyltransferase cyclodeaminase
chr21_-_41286846 1.13 ENSDART00000167339
msx2b
muscle segment homeobox 2b
chr21_-_39132283 1.12 ENSDART00000065143
unc119b
unc-119 homolog b (C. elegans)
chr15_+_9096765 1.11 ENSDART00000080196
si:dkey-202g17.3
si:dkey-202g17.3
chr23_+_36002332 1.07 ENSDART00000103139
hoxc8a
homeobox C8a
chr22_-_36915567 1.03 ENSDART00000029588
kng1
kininogen 1
chr8_-_17480730 0.99 ENSDART00000100667
skia
v-ski avian sarcoma viral oncogene homolog a
chr23_-_7892862 0.99 ENSDART00000157612
ENSDART00000165427
myt1b
myelin transcription factor 1b
chr10_-_32580145 0.98 ENSDART00000137608
dgat2
diacylglycerol O-acyltransferase 2
chr7_+_25052687 0.97 ENSDART00000110347
cyp26b1
cytochrome P450, family 26, subfamily b, polypeptide 1
chr13_+_30546398 0.94

chr10_+_31358236 0.94 ENSDART00000145562
robo4
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr9_-_12840621 0.94 ENSDART00000088042
myo10l3
myosin X-like 3
chr5_+_53178362 0.93 ENSDART00000169565
sat2b
spermidine/spermine N1-acetyltransferase family member 2b
chr11_-_30105047 0.92 ENSDART00000030794
tmem169a
transmembrane protein 169a
chr5_+_32282547 0.88 ENSDART00000135459
rpl12
ribosomal protein L12
chr20_-_38546922 0.88 ENSDART00000136303
itpkb
inositol-trisphosphate 3-kinase B
chr20_+_27565701 0.86

chr24_+_35899507 0.84 ENSDART00000122408
si:dkeyp-7a3.1
si:dkeyp-7a3.1
chr19_+_24398194 0.84 ENSDART00000080673
syt11a
synaptotagmin XIa
chr17_+_43041951 0.84 ENSDART00000154863
isca2
iron-sulfur cluster assembly 2
chr2_+_393439 0.83 ENSDART00000122138
mylk4a
myosin light chain kinase family, member 4a
chr6_+_37881015 0.81 ENSDART00000087311
oca2
oculocutaneous albinism II
chr14_+_23412305 0.80 ENSDART00000136909
gnpda1
glucosamine-6-phosphate deaminase 1
chr8_-_24276303 0.80

chr3_-_29992106 0.80 ENSDART00000153562
ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr7_-_34854886 0.78 ENSDART00000141211
hsd11b2
hydroxysteroid (11-beta) dehydrogenase 2
chr19_-_28192439 0.76 ENSDART00000135348
adcy2b
adenylate cyclase 2b (brain)
chr18_-_47186938 0.73

chr4_+_18974767 0.69 ENSDART00000066973
impdh1b
IMP (inosine 5'-monophosphate) dehydrogenase 1b
chr9_+_7745593 0.67 ENSDART00000061716
mnx2a
motor neuron and pancreas homeobox 2a
chr14_+_20809272 0.67 ENSDART00000139865
aldob
aldolase b, fructose-bisphosphate
chr10_-_32580373 0.65 ENSDART00000066793
dgat2
diacylglycerol O-acyltransferase 2
chr13_-_1980818 0.65 ENSDART00000110814
fam83b
family with sequence similarity 83, member B
chr2_-_49248076 0.64 ENSDART00000161156
kcnj9
potassium inwardly-rectifying channel, subfamily J, member 9
chr16_-_34304851 0.63 ENSDART00000145485
phactr4b
phosphatase and actin regulator 4b
chr12_-_31342432 0.61 ENSDART00000148603
acsl5
acyl-CoA synthetase long-chain family member 5
chr13_+_26943081 0.60 ENSDART00000146227
slc24a3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr15_-_12079779 0.60 ENSDART00000160427
si:dkey-202l22.6
si:dkey-202l22.6
chr11_-_29908609 0.59 ENSDART00000156196
scml2
sex comb on midleg-like 2 (Drosophila)
chr10_-_15090647 0.59 ENSDART00000038401
ENSDART00000155674
si:ch211-95j8.2
si:ch211-95j8.2
chr24_+_30343687 0.58 ENSDART00000162377
FP085414.1
ENSDARG00000100270
chr2_+_16983582 0.57 ENSDART00000091351
gk5
glycerol kinase 5 (putative)
chr24_+_35173816 0.54

chr14_-_51867502 0.52 ENSDART00000166924
ENSDARG00000098660
ENSDARG00000098660
chr6_+_3703684 0.51 ENSDART00000013743
gorasp2
golgi reassembly stacking protein 2
chr5_+_34381412 0.51 ENSDART00000134795
ankra2
ankyrin repeat, family A (RFXANK-like), 2
chr9_-_23222916 0.49 ENSDART00000022392
ENSDART00000122036
rnd3b
Rho family GTPase 3b
chr6_+_46968199 0.48

chr6_+_37880936 0.48 ENSDART00000087311
oca2
oculocutaneous albinism II
chr25_+_1773157 0.47

chr3_+_33209227 0.47 ENSDART00000128786
pyya
peptide YYa
chr24_-_16993914 0.45

chr13_-_13163647 0.45 ENSDART00000125883
ENSDART00000013534
fgfr3
fibroblast growth factor receptor 3
chr17_-_42778156 0.41 ENSDART00000140549
nkx2.2a
NK2 homeobox 2a
chr11_+_35896325 0.40 ENSDART00000163330
grm2b
glutamate receptor, metabotropic 2b
chr18_-_47186896 0.38

chr11_+_38858351 0.37 ENSDART00000155746
cdc42
cell division cycle 42
chr20_+_48950833 0.37 ENSDART00000159275
nkx2.2b
NK2 homeobox 2b
chr18_+_29166912 0.37 ENSDART00000089031
ppfibp2a
PTPRF interacting protein, binding protein 2a (liprin beta 2)
chr6_+_58837900 0.36 ENSDART00000157581
dctn2
dynactin 2 (p50)
chr8_+_21556157 0.36 ENSDART00000172190
ajap1
adherens junctions associated protein 1
chr1_-_33880029 0.36 ENSDART00000004361
klf5a
Kruppel-like factor 5a
chr25_-_12633686 0.35 ENSDART00000171144
ENSDART00000171834
klhdc4
kelch domain containing 4
chr6_-_26897413 0.35

chr13_-_30807799 0.34

chr3_+_24003840 0.34 ENSDART00000156204
si:ch211-246i5.5
si:ch211-246i5.5
chr10_+_44364064 0.33

chr7_-_33080261 0.33 ENSDART00000114041
anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr9_+_2756231 0.33 ENSDART00000123342
sp3a
sp3a transcription factor
chr20_-_26973962 0.32

chr10_+_31358307 0.31 ENSDART00000145562
robo4
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr20_+_27121126 0.30 ENSDART00000126919
ENSDART00000016014
chga
chromogranin A
chr18_+_20058028 0.30 ENSDART00000146957
uacaa
uveal autoantigen with coiled-coil domains and ankyrin repeats a
chr22_+_39110524 0.29 ENSDART00000153841
lmcd1
LIM and cysteine-rich domains 1
chr23_-_18972097 0.28 ENSDART00000133826
CR847953.1
ENSDARG00000057403
chr2_-_11864995 0.28 ENSDART00000080925
impad1
inositol monophosphatase domain containing 1
chr5_-_32282404 0.28 ENSDART00000166698
lrsam1
leucine rich repeat and sterile alpha motif containing 1
chr2_-_6380457 0.27 ENSDART00000092182
ppm1la
protein phosphatase, Mg2+/Mn2+ dependent, 1La
chr20_+_23843436 0.27 ENSDART00000050559
sh3rf1
SH3 domain containing ring finger 1
chr13_+_2213363 0.27 ENSDART00000019989
ENSDART00000165305
fbxo9
F-box protein 9
chr19_-_6215704 0.26 ENSDART00000104978
cica
capicua transcriptional repressor a
chr2_-_6380589 0.26 ENSDART00000092182
ppm1la
protein phosphatase, Mg2+/Mn2+ dependent, 1La
chr17_+_33388313 0.25 ENSDART00000077553
xdh
xanthine dehydrogenase
chr3_+_60367511 0.24 ENSDART00000128260
CABZ01087514.1
ENSDARG00000090861
chr5_-_4082749 0.23

chr6_+_12999420 0.23 ENSDART00000089725
ino80db
INO80 complex subunit Db
chr12_-_48278273 0.22

chr18_+_92690 0.21

chr5_-_32860888 0.20 ENSDART00000085636
ENSDARG00000060631
ENSDARG00000060631
chr24_-_10910835 0.20 ENSDART00000133530
asap1b
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1b
chr7_-_18348841 0.19 ENSDART00000111636
DTX4
deltex E3 ubiquitin ligase 4
chr15_-_34700453 0.14 ENSDART00000140882
ispd
isoprenoid synthase domain containing
chr19_-_38832599 0.14 ENSDART00000087639
smap2
small ArfGAP2
chr23_+_34392753 0.14

chr22_-_36915689 0.13 ENSDART00000029588
kng1
kininogen 1
chr7_-_6222134 0.13 ENSDART00000173197
hist1h4l
histone 1, H4, like
chr10_-_28638101 0.12 ENSDART00000177781
bbx
bobby sox homolog (Drosophila)
chr13_-_30807601 0.11

chr6_-_59412311 0.11

chr21_-_2322963 0.10 ENSDART00000160337
si:ch73-299h12.8
si:ch73-299h12.8
chr24_+_33478309 0.10 ENSDART00000122579
si:ch73-173p19.1
si:ch73-173p19.1
chr20_-_51585893 0.09 ENSDART00000151426
si:ch73-91k6.2
si:ch73-91k6.2
chr24_+_3177066 0.09

chr23_-_33783396 0.08 ENSDART00000130338
pou6f1
POU class 6 homeobox 1
chr17_-_31027949 0.08 ENSDART00000152016
eml1
echinoderm microtubule associated protein like 1
chr11_+_21949272 0.08 ENSDART00000122136
MDFI
MyoD family inhibitor
chr20_-_26973934 0.07

chr7_-_41871376 0.04 ENSDART00000110907
itfg1
integrin alpha FG-GAP repeat containing 1
chr2_-_6380096 0.04

chr2_-_38330046 0.04 ENSDART00000076503
ap1g2
adaptor-related protein complex 1, gamma 2 subunit
chr19_-_38832891 0.03 ENSDART00000087639
smap2
small ArfGAP2
chr9_+_41776562 0.01

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.5 1.6 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.4 1.3 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.4 1.1 GO:0052803 imidazole-containing compound metabolic process(GO:0052803) imidazole-containing compound catabolic process(GO:0052805)
0.4 1.4 GO:0072388 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.2 1.0 GO:0003322 pancreatic A cell development(GO:0003322)
0.2 0.9 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.2 1.3 GO:0042438 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.2 0.9 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.2 1.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 0.6 GO:0010747 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) regulation of organic acid transport(GO:0032890) positive regulation of organic acid transport(GO:0032892) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transport(GO:1903793) regulation of anion transmembrane transport(GO:1903959) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.2 1.8 GO:0042572 retinol metabolic process(GO:0042572)
0.2 1.2 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.2 0.8 GO:0034650 cortisol metabolic process(GO:0034650)
0.1 0.8 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.4 GO:0008347 glial cell migration(GO:0008347)
0.1 3.9 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 1.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.6 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.5 GO:2001287 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 0.8 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.1 0.3 GO:0046888 negative regulation of hormone secretion(GO:0046888)
0.1 0.5 GO:0019563 glycerol catabolic process(GO:0019563)
0.1 0.4 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 0.9 GO:0061337 cardiac conduction(GO:0061337)
0.1 0.7 GO:0006183 GMP biosynthetic process(GO:0006177) GTP biosynthetic process(GO:0006183) GMP metabolic process(GO:0046037)
0.1 1.1 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 0.7 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.8 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 0.9 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 0.4 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0 0.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.5 GO:0007631 feeding behavior(GO:0007631)
0.0 0.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 1.8 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 1.1 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.4 GO:0030719 P granule organization(GO:0030719)
0.0 1.9 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.4 GO:0033505 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0 0.3 GO:0046113 nucleobase catabolic process(GO:0046113)
0.0 1.6 GO:0007283 spermatogenesis(GO:0007283)
0.0 0.6 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037)
0.0 0.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 1.1 GO:0006865 amino acid transport(GO:0006865)
0.0 1.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.8 GO:0007269 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 1.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0007528 neuromuscular junction development(GO:0007528)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.6 GO:0030056 hemidesmosome(GO:0030056)
0.1 1.2 GO:0031430 M band(GO:0031430)
0.1 1.1 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 0.3 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.5 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.9 GO:0016459 myosin complex(GO:0016459)
0.0 0.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 10.0 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 1.9 GO:0031012 extracellular matrix(GO:0031012)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.9 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.4 1.1 GO:0005542 folic acid binding(GO:0005542) ammonia-lyase activity(GO:0016841)
0.4 1.4 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.3 0.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 3.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 0.9 GO:0019809 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.2 0.7 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.2 1.6 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.2 0.8 GO:0004016 adenylate cyclase activity(GO:0004016)
0.2 0.9 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 0.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 1.6 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.4 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.1 0.7 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 1.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 1.9 GO:0005518 collagen binding(GO:0005518)
0.1 0.9 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 0.3 GO:0030151 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725) molybdenum ion binding(GO:0030151)
0.1 0.6 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.9 GO:0098632 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 1.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.8 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 0.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.8 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.6 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 1.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.9 GO:0046332 SMAD binding(GO:0046332)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 1.3 GO:0003774 motor activity(GO:0003774)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 0.9 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 0.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 0.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 2.9 PID FGF PATHWAY FGF signaling pathway
0.0 0.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.9 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 1.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 2.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 2.2 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.1 0.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 2.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus