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Results for nkx2.5

Z-value: 0.96

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Transcription factors associated with nkx2.5

Gene Symbol Gene ID Gene Info
nkx2.5
ENSDARG00000018004 NK2 homeobox 5

Activity profile of nkx2.5 motif

Sorted Z-values of nkx2.5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx2.5

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr20_+_4567653 3.48

chr15_+_29153215 2.61 ENSDART00000156799
si:ch211-137a8.4
si:ch211-137a8.4
chr25_-_14472107 2.05

chr1_+_49894978 1.96 ENSDART00000020412
pkd2
polycystic kidney disease 2
chr20_+_4567603 1.79

chr15_-_18425091 1.73 ENSDART00000155866
zbtb16b
zinc finger and BTB domain containing 16b
chr3_+_32394653 1.69 ENSDART00000150897
si:ch73-367p23.2
si:ch73-367p23.2
chr8_+_48106836 1.67 ENSDART00000138717
si:ch211-263k4.2
si:ch211-263k4.2
chr5_-_42272455 1.65 ENSDART00000161586
flot2a
flotillin 2a
chr23_+_19827551 1.65 ENSDART00000073442
flna
filamin A, alpha (actin binding protein 280)
chr18_-_46243753 1.64 ENSDART00000145999
prx
periaxin
chr1_+_26330186 1.43 ENSDART00000102322
bnc2
basonuclin 2
chr10_-_39210658 1.43 ENSDART00000150193
slc37a4b
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr4_-_24310846 1.42 ENSDART00000017443
celf2
cugbp, Elav-like family member 2
chr16_-_46653204 1.26 ENSDART00000158341
tmem176l.3a
transmembrane protein 176l.3a
chr20_+_2443682 1.26 ENSDART00000131642
akap7
A kinase (PRKA) anchor protein 7
chr16_-_9785057 1.25 ENSDART00000113724
mal2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr7_-_47900199 1.25 ENSDART00000174262
mtss1lb
metastasis suppressor 1-like b
chr14_+_21531709 1.24 ENSDART00000144367
ctbp1
C-terminal binding protein 1
chr15_-_47277391 1.23 ENSDART00000151600
h3f3b.1
H3 histone, family 3B.1
chr5_-_248845 1.20 ENSDART00000127504
trabd2a
TraB domain containing 2A
chr23_-_35657313 1.18 ENSDART00000043429
jph2
junctophilin 2
KN150131v1_+_59098 1.17 ENSDART00000175590
CABZ01064941.1
ENSDARG00000106550
chr14_-_48951428 1.16 ENSDART00000157785
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr9_+_30483319 1.16 ENSDART00000148148
srpx
sushi-repeat containing protein, X-linked
chr12_+_6065116 1.16 ENSDART00000139054
sgms1
sphingomyelin synthase 1
chr14_-_7774262 1.13 ENSDART00000045109
zgc:92242
zgc:92242
chr12_-_17357133 1.13 ENSDART00000079115
papss2b
3'-phosphoadenosine 5'-phosphosulfate synthase 2b
chr6_-_39346614 1.13 ENSDART00000104074
zgc:158846
zgc:158846
chr24_-_2918801 1.12 ENSDART00000164776
fam69c
family with sequence similarity 69, member C
chr12_+_2835894 1.12 ENSDART00000165225
prkar1ab
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b
chr21_-_13571753 1.10 ENSDART00000065819
clic3
chloride intracellular channel 3
chr13_-_49826330 1.08 ENSDART00000099475
nid1a
nidogen 1a
chr17_+_45824480 1.07

chr9_-_12726136 1.06

chr22_+_5657904 1.05 ENSDART00000138102
dnase1l4.2
deoxyribonuclease 1 like 4, tandem duplicate 2
chr4_+_21996784 1.05 ENSDART00000040266
myf6
myogenic factor 6
chr21_-_28486800 1.05 ENSDART00000077910
epdl2
ependymin-like 2
chr11_+_37639045 1.02 ENSDART00000111157
si:ch211-112f3.4
si:ch211-112f3.4
chr11_-_33697442 1.01 ENSDART00000087597
col6a2
collagen, type VI, alpha 2
chr3_+_22246697 1.01 ENSDART00000155597
arhgap27l
Rho GTPase activating protein 27, like
chr10_+_5693933 0.97 ENSDART00000159769
pam
peptidylglycine alpha-amidating monooxygenase
chr1_-_25272318 0.97 ENSDART00000134192
synpo2b
synaptopodin 2b
chr5_-_70939686 0.96

chr18_+_18598885 0.95

chr20_-_28739099 0.94 ENSDART00000135513
rgs6
regulator of G protein signaling 6
chr9_-_22347397 0.92 ENSDART00000146188
crygm2d16
crystallin, gamma M2d16
chr22_+_15946773 0.89 ENSDART00000144545
rc3h1a
ring finger and CCCH-type domains 1a
chr9_-_35135414 0.89 ENSDART00000140563
dcun1d2a
DCN1, defective in cullin neddylation 1, domain containing 2a
chr3_-_7220340 0.88

chr16_-_24696036 0.87

chr20_+_23599157 0.87 ENSDART00000149922
palld
palladin, cytoskeletal associated protein
chr24_-_2278409 0.86

chr15_-_41288480 0.85 ENSDART00000155359
smco4
single-pass membrane protein with coiled-coil domains 4
chr25_-_31881585 0.84 ENSDART00000123999
ENSDART00000158091
ENSDARG00000100731
ENSDARG00000100731
chr1_-_44942144 0.84 ENSDART00000044057
sept3
septin 3
chr17_-_44135924 0.83 ENSDART00000156648
otx2
orthodenticle homeobox 2
chr20_+_44413431 0.82 ENSDART00000114660
opn8b
opsin 8, group member b
chr6_+_24717985 0.81 ENSDART00000165609
barhl2
BarH-like homeobox 2
chr18_+_46384462 0.80 ENSDART00000024202
daw1
dynein assembly factor with WDR repeat domains 1
chr10_-_24401876 0.79 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr13_+_22134507 0.78 ENSDART00000060576
myoz1a
myozenin 1a
chr1_-_44942047 0.76 ENSDART00000044057
sept3
septin 3
chr7_-_32604392 0.76 ENSDART00000132504
ano5b
anoctamin 5b
chr22_+_18364282 0.76 ENSDART00000088270
yjefn3
YjeF N-terminal domain containing 3
chr6_-_22869821 0.74 ENSDART00000167674
mif4gda
MIF4G domain containing a
chr1_+_49894685 0.73 ENSDART00000020412
pkd2
polycystic kidney disease 2
chr21_+_45693978 0.71 ENSDART00000160324
CABZ01102047.1
ENSDARG00000099648
chr3_-_33295814 0.71 ENSDART00000146294
rpl23
ribosomal protein L23
chr22_+_1320235 0.70

chr22_+_1404309 0.70 ENSDART00000161813
zgc:101130
zgc:101130
chr17_-_610651 0.70

chr14_-_205130 0.69 ENSDART00000035581
ENSDART00000158725
ENSDART00000163549
OTOP1
otopetrin 1
chr2_-_43997672 0.69 ENSDART00000005449
zeb1a
zinc finger E-box binding homeobox 1a
KN149830v1_-_23361 0.68

chr6_-_40660116 0.68 ENSDART00000154359
ppil1
peptidylprolyl isomerase (cyclophilin)-like 1
chr12_+_22455344 0.67 ENSDART00000172053
capgb
capping protein (actin filament), gelsolin-like b
chr19_+_46647893 0.65 ENSDART00000162785
ENSDART00000171251
ENSDART00000164938
mapk15
mitogen-activated protein kinase 15
chr13_-_7897936 0.63 ENSDART00000139728
si:ch211-250c4.4
si:ch211-250c4.4
chr18_+_41243277 0.63

chr25_-_10919875 0.63 ENSDART00000099572
mespab
mesoderm posterior ab
chr25_+_35602451 0.61 ENSDART00000036147
irx5b
iroquois homeobox 5b
chr16_+_9718837 0.60 ENSDART00000047920
enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr10_+_2952793 0.58

chr19_+_26838851 0.57 ENSDART00000136244
npr1a
natriuretic peptide receptor 1a
chr16_-_2570425 0.57

chr19_-_31785558 0.57 ENSDART00000046609
scin
scinderin
chr22_-_337198 0.57

chr4_-_13903253 0.55 ENSDART00000032805
gxylt1b
glucoside xylosyltransferase 1b
chr7_-_47900141 0.55 ENSDART00000174262
mtss1lb
metastasis suppressor 1-like b
chr11_-_3609813 0.55 ENSDART00000136577
itih3a
inter-alpha-trypsin inhibitor heavy chain 3a
chr7_-_17129072 0.55

chr7_+_40367221 0.54 ENSDART00000052236
mnx1
motor neuron and pancreas homeobox 1
chr15_-_41777233 0.53 ENSDART00000154230
ftr90
finTRIM family, member 90
chr8_-_38316609 0.53

chr1_+_26330335 0.51 ENSDART00000102322
bnc2
basonuclin 2
chr16_+_55008251 0.51 ENSDART00000176995
CABZ01087388.1
ENSDARG00000106538
chr1_-_30772653 0.51 ENSDART00000087115
rims1b
regulating synaptic membrane exocytosis 1b
chr23_+_4385722 0.50 ENSDART00000146302
ENSDART00000136792
ENSDART00000135027
sgk2a
serum/glucocorticoid regulated kinase 2a
chr22_+_38206685 0.47 ENSDART00000104527
tm4sf18
transmembrane 4 L six family member 18
chr21_-_39900518 0.47 ENSDART00000175055
CABZ01065291.1
ENSDARG00000107374
chr16_+_24046789 0.46

chr1_+_50348973 0.46

chr9_-_2416300 0.46

chr11_+_38013564 0.45 ENSDART00000171496
CDK18
cyclin dependent kinase 18
chr1_-_31117154 0.44

chr13_-_50299821 0.44 ENSDART00000170527
vent
ventral expressed homeobox
chr11_-_16067646 0.43

chr8_+_17803229 0.42 ENSDART00000175436
slc44a5b
solute carrier family 44, member 5b
chr23_-_28367816 0.41 ENSDART00000003548
znf385a
zinc finger protein 385A
chr4_-_4110484 0.41 ENSDART00000138221
lmod2b
leiomodin 2 (cardiac) b
chr6_+_58837900 0.40 ENSDART00000157581
dctn2
dynactin 2 (p50)
chr4_-_74789596 0.39 ENSDART00000174356
ENSDART00000174313
si:ch73-158p21.3
si:ch73-158p21.3
chr5_+_68352513 0.39 ENSDART00000160775
ENSDARG00000102513
ENSDARG00000102513
chr18_-_43890514 0.39 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr7_-_68033217 0.38

chr16_-_31868810 0.36 ENSDART00000058737
cdc42l
cell division cycle 42, like
chr14_-_48951396 0.36 ENSDART00000157785
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr12_-_7790309 0.36 ENSDART00000148673
ank3b
ankyrin 3b
chr18_-_3030681 0.35 ENSDART00000161848
ints4
integrator complex subunit 4
chr3_+_52746124 0.35

chr3_+_32394550 0.34 ENSDART00000150897
si:ch73-367p23.2
si:ch73-367p23.2
chr24_-_33361897 0.34 ENSDART00000128943
nrbp2b
nuclear receptor binding protein 2b
chr11_-_25222937 0.34

chr3_+_19582280 0.34 ENSDART00000109409
mrc2
mannose receptor, C type 2
chr1_+_46487300 0.34 ENSDART00000158432
ENSDART00000074450
morc3b
MORC family CW-type zinc finger 3b
chr1_+_33510660 0.34 ENSDART00000147201
slc5a7a
solute carrier family 5 (sodium/choline cotransporter), member 7a
chr5_+_31562242 0.33 ENSDART00000134472
taok3b
TAO kinase 3b
chr20_+_27068108 0.33 ENSDART00000132434
ENSDART00000029781
ahsa1a
AHA1, activator of heat shock protein ATPase homolog 1a
chr13_-_49920975 0.33 ENSDART00000165066
eif2ak2
eukaryotic translation initiation factor 2-alpha kinase 2
chr11_+_25266623 0.32 ENSDART00000154213
tfe3b
transcription factor binding to IGHM enhancer 3b
chr13_-_50299643 0.31 ENSDART00000170527
vent
ventral expressed homeobox
chr15_+_24277664 0.31 ENSDART00000155502
sez6b
seizure related 6 homolog b
chr10_+_22043094 0.30 ENSDART00000035188
kcnip1b
Kv channel interacting protein 1 b
chr1_-_54593214 0.29 ENSDART00000152807
si:ch211-286b5.5
si:ch211-286b5.5
chr2_-_24735186 0.29 ENSDART00000141365
zgc:154006
zgc:154006
chr15_-_1519571 0.28 ENSDART00000129356
si:dkeyp-97b10.3
si:dkeyp-97b10.3
chr13_-_6089739 0.28 ENSDART00000159052
si:zfos-1056e6.1
si:zfos-1056e6.1
chr6_-_45867149 0.27 ENSDART00000062459
rbm19
RNA binding motif protein 19
chr6_-_25962268 0.27 ENSDART00000076997
lmo4b
LIM domain only 4b
chr22_-_12130441 0.25 ENSDART00000146785
tmem163b
transmembrane protein 163b
chr14_-_32956886 0.25 ENSDART00000075056
rab41
RAB41, member RAS oncogene family
chr8_+_25594106 0.24

chr19_+_43524098 0.23 ENSDART00000129362
eef1a1l2
eukaryotic translation elongation factor 1 alpha 1, like 2
chr16_-_5205633 0.23 ENSDART00000082071
bckdhb
branched chain keto acid dehydrogenase E1, beta polypeptide
chr3_-_3589844 0.23 ENSDART00000140482
ENSDARG00000079723
ENSDARG00000079723
chr19_-_44064157 0.23 ENSDART00000144058
si:ch211-193k19.2
si:ch211-193k19.2
chr4_+_71965053 0.23 ENSDART00000150765
si:ch211-165i18.2
si:ch211-165i18.2
chr4_-_47142181 0.22 ENSDART00000150426
znf1064
zinc finger protein 1064
chr1_+_53384116 0.22 ENSDART00000149760
triobpa
TRIO and F-actin binding protein a
chr11_-_232269 0.21 ENSDART00000172818
si:ch1073-456m8.1
si:ch1073-456m8.1
chr4_+_13430131 0.21 ENSDART00000137200
si:dkey-39a18.1
si:dkey-39a18.1
KN150266v1_+_74105 0.21

chr3_-_7275872 0.21 ENSDART00000132197
BX005085.4
ENSDARG00000102658
chr22_+_5633739 0.21 ENSDART00000106141
tma7
translation machinery associated 7 homolog
chr2_-_31627340 0.20

chr14_-_16171165 0.20 ENSDART00000089021
canx
calnexin
chr6_-_23830912 0.20

chr3_-_41649319 0.20 ENSDART00000049687
grifin
galectin-related inter-fiber protein
chr8_+_30912152 0.19 ENSDART00000171400
derl3
derlin 3
chr10_+_26149600 0.17

chr15_-_39783178 0.17

chr12_-_3672263 0.17

chr16_-_42857240 0.17

chr9_+_37510430 0.17 ENSDART00000100622
slc15a2
solute carrier family 15 (oligopeptide transporter), member 2
chr10_+_21657291 0.16

chr9_+_17855021 0.15 ENSDART00000166566
ENSDART00000060356
dgkh
diacylglycerol kinase, eta
chr14_+_11457256 0.14 ENSDART00000110004
frmpd3
FERM and PDZ domain containing 3
chr22_-_19527759 0.14 ENSDART00000105485
si:dkey-78l4.14
si:dkey-78l4.14
chr3_+_19582238 0.14 ENSDART00000109409
mrc2
mannose receptor, C type 2
chr3_+_13040717 0.14

chr9_+_37510380 0.11 ENSDART00000100622
slc15a2
solute carrier family 15 (oligopeptide transporter), member 2
chr10_+_29425917 0.11

chr3_+_23523703 0.10 ENSDART00000078428
hoxb13a
homeobox B13a
chr14_+_11457009 0.10 ENSDART00000110004
frmpd3
FERM and PDZ domain containing 3
chr12_-_13690539 0.09 ENSDART00000078021
foxh1
forkhead box H1
chr7_-_54990861 0.09 ENSDART00000122603
rnf166
ring finger protein 166
chr17_-_53237500 0.08

chr18_+_17503828 0.08 ENSDART00000161827
si:dkey-102f14.5
si:dkey-102f14.5
chr4_+_20588066 0.06

chr14_-_2379419 0.05

chr14_+_26461172 0.05 ENSDART00000125289
ahnak
AHNAK nucleoprotein
chr18_+_41242498 0.03 ENSDART00000138552
ENSDART00000145863
trip12
thyroid hormone receptor interactor 12
chr23_+_25365281 0.02 ENSDART00000016248
pa2g4b
proliferation-associated 2G4, b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0044246 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246) response to oscillatory fluid shear stress(GO:0097702) cellular response to oscillatory fluid shear stress(GO:0097704)
0.5 1.6 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.4 1.7 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.3 1.7 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.2 0.7 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.2 1.0 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.2 1.2 GO:0045056 transcytosis(GO:0045056)
0.2 1.1 GO:0050428 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.6 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.1 1.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 1.8 GO:0097178 ruffle assembly(GO:0097178)
0.1 0.8 GO:0032371 regulation of sterol transport(GO:0032371) regulation of cholesterol transport(GO:0032374)
0.1 1.0 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.1 0.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.6 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 1.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.5 GO:0016266 O-glycan processing(GO:0016266)
0.1 1.1 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.1 1.9 GO:0039020 pronephric nephron tubule development(GO:0039020)
0.1 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.7 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.1 0.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274) acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.1 0.8 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.1 0.9 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.1 0.8 GO:0007602 phototransduction(GO:0007602)
0.1 1.2 GO:0051014 actin filament severing(GO:0051014)
0.1 0.3 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.1 1.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.5 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.9 GO:0050670 regulation of mononuclear cell proliferation(GO:0032944) regulation of T cell proliferation(GO:0042129) regulation of lymphocyte proliferation(GO:0050670) regulation of leukocyte proliferation(GO:0070663)
0.0 1.0 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 1.9 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.6 GO:0007379 somite specification(GO:0001757) segment specification(GO:0007379)
0.0 0.4 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 1.9 GO:0006821 chloride transport(GO:0006821)
0.0 0.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.7 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.1 GO:0015835 peptidoglycan transport(GO:0015835) nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0 0.2 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.9 GO:0007601 visual perception(GO:0007601)
0.0 2.5 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 0.4 GO:0016180 snRNA processing(GO:0016180)
0.0 0.3 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.3 GO:0006829 zinc II ion transport(GO:0006829)
0.0 1.2 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0030314 junctional membrane complex(GO:0030314)
0.3 2.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.3 1.7 GO:0016600 flotillin complex(GO:0016600)
0.3 2.1 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.3 1.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.6 GO:0002102 podosome(GO:0002102)
0.1 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 1.1 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.7 GO:0030018 Z disc(GO:0030018)
0.0 1.2 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.9 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0043204 perikaryon(GO:0043204)
0.0 1.2 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.2 GO:0000786 nucleosome(GO:0000786)
0.0 0.4 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.7 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.4 1.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 1.0 GO:0016842 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) amidine-lyase activity(GO:0016842)
0.2 0.8 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.2 1.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 0.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 1.1 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2 1.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.2 0.8 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.7 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.9 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 1.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.5 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.6 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.8 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.3 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.1 0.7 GO:0008494 translation activator activity(GO:0008494)
0.1 0.3 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.9 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.7 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 1.9 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.5 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 2.7 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0042936 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 1.1 GO:0051287 NAD binding(GO:0051287)
0.0 1.4 GO:0015293 symporter activity(GO:0015293)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 1.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.5 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 1.6 GO:0060090 binding, bridging(GO:0060090)
0.0 4.8 GO:0003779 actin binding(GO:0003779)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.2 PID ATM PATHWAY ATM pathway
0.0 1.0 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.3 PID CERAMIDE PATHWAY Ceramide signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.9 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC