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Results for nkx6.1

Z-value: 1.00

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Transcription factors associated with nkx6.1

Gene Symbol Gene ID Gene Info
ENSDARG00000022569 NK6 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx6.1dr10_dc_chr21_+_19034242_190342880.887.8e-06Click!

Activity profile of nkx6.1 motif

Sorted Z-values of nkx6.1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx6.1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr20_-_22576513 3.82 ENSDART00000103510
platelet-derived growth factor receptor, alpha polypeptide
chr16_+_46145286 3.73 ENSDART00000172232
synaptic vesicle glycoprotein 2A
chr12_+_24221087 2.94 ENSDART00000088178
neurexin 1a
chr9_-_32942783 2.83 ENSDART00000060006
oligodendrocyte lineage transcription factor 2
chr10_+_39141022 2.41 ENSDART00000158245
si:ch73-1a9.3
chr16_+_23516127 2.35 ENSDART00000004679
ictacalcin
chr14_+_46419051 2.25 ENSDART00000112377
microtubule-associated protein 1 light chain 3 gamma, like
chr6_+_56157608 2.10 ENSDART00000149665
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr17_+_23278879 2.08 ENSDART00000153652
zgc:165461
chr24_-_21778717 2.03 ENSDART00000131944
transgelin 3b
chr2_+_49358871 1.96 ENSDART00000179089
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba
chr3_+_56970554 1.95 ENSDART00000162930
BAH domain and coiled-coil containing 1a
chr20_-_29517770 1.94 ENSDART00000147464
ryanodine receptor 3
chr7_-_25623974 1.93 ENSDART00000173602
CD99 molecule-like 2
chr23_-_7740845 1.93 ENSDART00000172451
pleiomorphic adenoma gene-like 2
chr17_+_15425559 1.89 ENSDART00000026180
fatty acid binding protein 7, brain, a
chr15_-_4537178 1.88 ENSDART00000155619
ENSDART00000128602
transcription factor Dp-2
chr12_+_20230575 1.81 ENSDART00000066383
hemoglobin, alpha embryonic 5
chr11_+_23522743 1.79 ENSDART00000121874
neurofascin homolog (chicken) a
chr15_-_18159904 1.75 ENSDART00000170874
pleckstrin homology-like domain, family B, member 1b
chr21_+_28441951 1.75 ENSDART00000077887
solute carrier family 22 (organic anion transporter), member 6, like
chr18_-_3056732 1.71 ENSDART00000162657
ribosomal protein S3
chr17_-_29102320 1.70 ENSDART00000104204
forkhead box G1a
chr20_-_9107294 1.68 ENSDART00000140792
OMA1 zinc metallopeptidase
chr11_+_10925475 1.68 ENSDART00000064860
RNA binding motif, single stranded interacting protein 1a
chr24_+_5205878 1.63 ENSDART00000106488
ENSDART00000005901
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr14_+_20045365 1.58 ENSDART00000167637
AF4/FMR2 family, member 2
chr18_+_26437604 1.56 ENSDART00000060245
cathepsin H
chr5_+_38236956 1.56 ENSDART00000160236
Fraser extracellular matrix complex subunit 1
chr11_+_14142126 1.55 ENSDART00000102520
paralemmin 1a
chr1_-_4757890 1.50 ENSDART00000114035
motor neuron and pancreas homeobox 2b
chr4_-_15442828 1.50 ENSDART00000157414
plexin A4
chr6_-_54816183 1.47 ENSDART00000148462
troponin I type 1b (skeletal, slow)
chr6_+_3873114 1.47 ENSDART00000159952
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Bb
chr16_-_42990753 1.47 ENSDART00000149317
hemochromatosis type 2
chr20_+_33391554 1.46 ENSDART00000024104
MYCN proto-oncogene, bHLH transcription factor
chr22_-_37417903 1.44 ENSDART00000149948
ENSDARG00000095844
chr1_+_13779755 1.44

chr18_+_29424354 1.43 ENSDART00000014703
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a)
chr16_-_17439735 1.43 ENSDART00000144392
zyxin
chr3_-_35928594 1.38

chr20_-_3970778 1.38 ENSDART00000178724
ENSDART00000178565
tripartite motif containing 67
chr7_+_6517248 1.38 ENSDART00000102681
purine nucleoside phosphorylase 5a
chr21_+_28408329 1.37 ENSDART00000077871
phosphorylase, glycogen, muscle A
chr19_+_32579358 1.37 ENSDART00000021798
fatty acid binding protein 11a
chr21_-_22510751 1.37 ENSDART00000169870
myosin VB
chr16_+_23172295 1.36 ENSDART00000167518
ENSDART00000161087
ephrin-A3b
chr24_-_6048914 1.36 ENSDART00000146830
ENSDART00000021981
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr25_+_14411153 1.35 ENSDART00000015681
developing brain homeobox 1b
chr8_+_39964695 1.34 ENSDART00000073782
gamma-glutamyltransferase 5a
chr3_+_17387551 1.33 ENSDART00000104549
hypocretin (orexin) neuropeptide precursor
chr5_-_40707316 1.33 ENSDART00000161932
natriuretic peptide receptor 3
chr14_-_17258072 1.33 ENSDART00000082667
fibroblast growth factor receptor-like 1a
chr23_-_23474703 1.32 ENSDART00000078936
hairy-related 9
chr18_-_43890514 1.31 ENSDART00000087382
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr1_+_26330186 1.28 ENSDART00000102322
basonuclin 2
chr2_-_34010299 1.28 ENSDART00000140910
patched 2
chr3_-_6078015 1.28 ENSDART00000165715
ENSDARG00000098850
chr3_-_29768364 1.27 ENSDART00000020311
ribosomal protein L27
chr16_+_13928844 1.24 ENSDART00000090191
folliculin
chr22_-_13018196 1.24 ENSDART00000028787
aryl hydrocarbon receptor 1b
chr21_-_25567978 1.24 ENSDART00000133134
EGF containing fibulin-like extracellular matrix protein 2b
chr1_-_40208544 1.23 ENSDART00000027463
H6 family homeobox 4
chr23_+_36023748 1.21

chr14_-_17257773 1.21 ENSDART00000082667
fibroblast growth factor receptor-like 1a
chr6_+_23787804 1.21 ENSDART00000163188
zinc finger protein 648
chr24_+_21395671 1.21 ENSDART00000091529
WAS protein family, member 3b
chr16_-_28943421 1.20 ENSDART00000149501
si:dkey-239n17.4
chr7_+_34018862 1.19 ENSDART00000123498
fin bud initiation factor b
chr21_+_17731439 1.19 ENSDART00000124173
retinoid X receptor, alpha a
chr16_+_29060022 1.18 ENSDART00000088023
gon-4-like (C. elegans)
chr3_-_45779817 1.16 ENSDART00000164361
glucagon receptor a
chr23_+_20936374 1.16 ENSDART00000129992
paired box 7b
chr23_+_11350727 1.14

chr22_+_16509286 1.14 ENSDART00000083063
T-cell acute lymphocytic leukemia 1
chr12_-_10372055 1.13 ENSDART00000052001
eukaryotic elongation factor 2 kinase
chr18_+_48426375 1.13

chr4_-_2615160 1.12 ENSDART00000140760
E2F transcription factor 7
chr21_-_11539798 1.12 ENSDART00000144770
calpastatin
chr1_-_40208469 1.12 ENSDART00000027463
H6 family homeobox 4
chr2_-_23348612 1.12 ENSDART00000110373
zinc finger protein 414
chr2_-_10555152 1.12 ENSDART00000150166
guanine nucleotide binding protein (G protein), gamma 12a
chr2_-_36058327 1.11 ENSDART00000003550
nicotinamide nucleotide adenylyltransferase 2
chr9_-_20562293 1.11 ENSDART00000113418
immunoglobulin superfamily, member 3
chr19_-_7069920 1.10 ENSDART00000145741
zinc finger protein 384 like
chr18_-_19467100 1.10 ENSDART00000060363
ribosomal protein L4
chr9_-_31467299 1.10 ENSDART00000022204
zic family member 5 (odd-paired homolog, Drosophila)
chr24_-_14447773 1.09

chr5_-_71643185 1.08 ENSDART00000029014
paired box 8
chr19_+_31046291 1.08 ENSDART00000052124
family with sequence similarity 49, member A-like
chr20_-_22478716 1.08 ENSDART00000110967
ENSDART00000011135
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a
chr15_-_20088439 1.07 ENSDART00000161379
autism susceptibility candidate 2b
chr22_+_12746080 1.06 ENSDART00000044683
formimidoyltransferase cyclodeaminase
chr8_-_34077387 1.06 ENSDART00000159208
ENSDART00000040126
ENSDART00000048994
ENSDART00000098822
pre-B-cell leukemia homeobox 3b
chr14_-_4166292 1.05 ENSDART00000127318
FERM and PDZ domain containing 1b
chr14_-_20760787 1.05

chr9_-_43736549 1.05 ENSDART00000140526
zinc finger protein 385B
chr16_+_26900732 1.04 ENSDART00000042895
cadherin 17, LI cadherin (liver-intestine)
chr2_-_40170303 1.04 ENSDART00000165602
eph receptor A4a
chr21_+_28921734 1.04 ENSDART00000166575
protein phosphatase 3, catalytic subunit, alpha isozyme
chr12_-_5693715 1.03 ENSDART00000105887
distal-less homeobox 4b
chr10_-_33678206 1.02 ENSDART00000128049
hormonally up-regulated Neu-associated kinase
chr14_+_14356509 1.01 ENSDART00000170211
centrin, EF-hand protein, 2
chr24_+_17125429 1.01 ENSDART00000017605
sperm associated antigen 6
chr15_-_14616083 1.01 ENSDART00000171169
numb homolog (Drosophila)-like
chr6_-_2294751 1.01 ENSDART00000165223
pre-B-cell leukemia homeobox 1b
chr7_+_19300351 1.00 ENSDART00000169060
si:ch211-212k18.5
chr6_-_43094573 1.00 ENSDART00000084389
leucine rich repeat neuronal 1
chr25_+_2933235 0.99 ENSDART00000029580
ferritin, heavy polypeptide 1b
chr1_-_518543 0.98 ENSDART00000138032
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr19_+_22478256 0.98 ENSDART00000100181
spalt-like transcription factor 3b
chr17_-_31642673 0.98 ENSDART00000030448
visual system homeobox 2
chr2_+_33907298 0.97

chr8_-_23591082 0.97 ENSDART00000025024
solute carrier family 38, member 5b
chr5_-_67233396 0.96 ENSDART00000051833
ENSDART00000124890
GS homeobox 1
chr13_+_28617462 0.96 ENSDART00000101633
prominin 2
chr13_+_33151628 0.96 ENSDART00000135200
coiled-coil domain containing 28B
chr16_-_13733759 0.96 ENSDART00000164344
si:dkeyp-69b9.6
chr3_+_61924544 0.95 ENSDART00000090370
NADPH oxidase organizer 1a
chr25_+_24193604 0.95 ENSDART00000083407
beta-1,4-N-acetyl-galactosaminyl transferase 4a
chr20_-_21031504 0.95 ENSDART00000152726
BTB (POZ) domain containing 6b
chr22_-_13325409 0.95 ENSDART00000154095
si:ch211-227m13.1
chr2_+_33343287 0.94 ENSDART00000056655
Kruppel-like factor 17
chr16_+_24766043 0.94 ENSDART00000114304
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like
chr13_-_252864 0.94

chr1_-_11474337 0.93 ENSDART00000149913
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr15_-_1858350 0.93 ENSDART00000082026
matrix metallopeptidase 28
chr5_-_32687349 0.93 ENSDART00000004238
ribosomal protein L7a
chr5_+_62987426 0.92 ENSDART00000178937
dynamin 1b
chr20_-_14158114 0.92 ENSDART00000009549
Rh-associated glycoprotein
chr11_+_36983626 0.90 ENSDART00000170209
interleukin 17 receptor C
chr6_+_24299180 0.90 ENSDART00000167482
transforming growth factor, beta receptor III
chr20_+_34417665 0.89 ENSDART00000153207
influenza virus NS1A binding protein a
chr19_-_7069850 0.89 ENSDART00000145741
zinc finger protein 384 like
chr1_-_30801520 0.89 ENSDART00000007770
ladybird homeobox 1b
chr21_+_10663517 0.88 ENSDART00000074833
retinal homeobox gene 3
chr24_+_30343717 0.88 ENSDART00000162377
ENSDARG00000100270
chr13_-_31165867 0.88 ENSDART00000030946
PR domain containing 8
chr8_-_19166630 0.88

chr5_+_36431824 0.87 ENSDART00000045036
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr7_-_58649991 0.86 ENSDART00000167076
mannose receptor, C type 1a
chr9_-_41608298 0.86

chr23_+_23094125 0.86 ENSDART00000146415
ENSDART00000146463
sterile alpha motif domain containing 11
chr1_-_25600988 0.86 ENSDART00000160381
CXXC finger 4
chr10_+_38582701 0.85 ENSDART00000144329
alkaline ceramidase 3
chr15_+_29343644 0.85 ENSDART00000170537
ENSDART00000128973
RAP1 GTPase activating protein 2a
chr18_+_24935499 0.85

chr3_+_18406137 0.85 ENSDART00000158791
chromobox homolog 4 (Pc class homolog, Drosophila)
chr17_+_30352361 0.85 ENSDART00000076611
growth regulation by estrogen in breast cancer 1
chr14_+_30568242 0.85

chr19_-_31815128 0.84 ENSDART00000137292
transmembrane protein 106Bb
chr23_+_35996491 0.84 ENSDART00000127384
homeobox C9a
chr6_-_8075384 0.84 ENSDART00000129674
solute carrier family 44 (choline transporter), member 2
chr14_-_2682064 0.83 ENSDART00000161677
si:dkey-201i24.6
chr3_-_34208423 0.83 ENSDART00000151634
trinucleotide repeat containing 6C1
chr17_+_25500291 0.83 ENSDART00000041721
crystallin beta-gamma domain containing 1a
chr20_+_28531684 0.83 ENSDART00000123387
D4, zinc and double PHD fingers, family 3
chr15_+_46141934 0.83 ENSDART00000154388
wu:fb18f06
chr23_+_6043862 0.82

chr2_+_3370130 0.82 ENSDART00000098391
wingless-type MMTV integration site family, member 9A
chr15_-_23441268 0.82 ENSDART00000078570
C1q and TNF related 5
chr25_-_5883620 0.82 ENSDART00000136054
sorting nexin 22
chr22_-_15930756 0.82 ENSDART00000080047
epidermal growth factor receptor pathway substrate 15-like 1a
chr3_-_41370116 0.82

chr14_+_2969679 0.81 ENSDART00000044678
ENSDARG00000034011
chr12_-_26339002 0.81 ENSDART00000153214
synaptopodin 2-like b
chr11_-_18068313 0.79

chr11_-_37730181 0.79 ENSDART00000102870
solute carrier family 41 (magnesium transporter), member 1
chr17_-_47893203 0.78

chr22_-_864745 0.78 ENSDART00000035514
choline/ethanolamine phosphotransferase 1b
chr8_+_26502828 0.76 ENSDART00000046863
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl
chr5_-_33156615 0.76 ENSDART00000159058
DAB2 interacting protein b
chr23_-_22186674 0.76 ENSDART00000142474
polyhomeotic homolog 2a (Drosophila)
chr3_-_39554155 0.75 ENSDART00000015393
B9 protein domain 1
chr17_+_29259577 0.75 ENSDART00000049399
ankyrin repeat domain 9
chr11_+_14373731 0.74 ENSDART00000161879
ENSDARG00000099220
chr14_+_36156947 0.74

chr10_-_43200499 0.74 ENSDART00000171494
single-stranded DNA binding protein 2
chr5_-_44229464 0.74 ENSDART00000019104
fructose-1,6-bisphosphatase 2
chr16_-_45211650 0.73 ENSDART00000165186
si:dkey-33i11.9
chr13_-_28177612 0.73 ENSDART00000045351
ladybird homeobox 1a
chr10_+_13042496 0.73 ENSDART00000158919
lysophosphatidic acid receptor 1
chr25_+_28717079 0.73 ENSDART00000162854
pyruvate kinase, muscle, b
chr8_-_11512545 0.72 ENSDART00000133932
si:ch211-248e11.2
chr7_+_54410044 0.72

chr16_-_41515399 0.71 ENSDART00000169116
copine IVa
chr20_-_37587804 0.71 ENSDART00000166106
si:ch211-202p1.5
chr10_+_32739166 0.71 ENSDART00000063551
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr24_+_9272045 0.70 ENSDART00000132724
si:ch211-285f17.1
chr21_+_6858073 0.69 ENSDART00000139493
olfactomedin 1b
chr19_+_5562107 0.68 ENSDART00000082080
junction plakoglobin b
chr5_-_47520995 0.68 ENSDART00000144252
ENSDARG00000095715
chr18_-_7184699 0.68 ENSDART00000135587
CD9 molecule a
chr14_+_160149 0.68 ENSDART00000158405
ENSDART00000158072
glypican 2
chr25_+_2909562 0.68 ENSDART00000149360
mannose phosphate isomerase
chr9_+_34832049 0.68 ENSDART00000100735
ENSDART00000133996
short stature homeobox
chr8_-_17580655 0.67

chr20_-_23526954 0.67 ENSDART00000004625
zygote arrest 1
chr9_-_3700395 0.67 ENSDART00000102900
Sp5 transcription factor a
chr3_+_28822408 0.66 ENSDART00000133528
lectin, galactoside-binding, soluble, 2a

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0021742 abducens nucleus development(GO:0021742)
0.5 1.6 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.5 1.4 GO:0003242 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.4 1.3 GO:0001659 temperature homeostasis(GO:0001659) sleep(GO:0030431)
0.4 3.8 GO:0003315 heart rudiment formation(GO:0003315)
0.4 1.1 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.4 1.1 GO:0032875 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.4 1.4 GO:0006751 glutathione catabolic process(GO:0006751)
0.4 0.7 GO:0050886 endocrine process(GO:0050886)
0.4 1.1 GO:0052805 imidazole-containing compound metabolic process(GO:0052803) imidazole-containing compound catabolic process(GO:0052805)
0.3 0.9 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.3 0.9 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.3 1.2 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.3 2.1 GO:0030183 B cell differentiation(GO:0030183)
0.3 1.0 GO:0021559 auditory receptor cell fate commitment(GO:0009912) trigeminal nerve development(GO:0021559) inner ear receptor cell fate commitment(GO:0060120)
0.3 1.3 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.3 0.8 GO:0032616 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.3 2.5 GO:0021592 fourth ventricle development(GO:0021592)
0.2 1.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 1.0 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 0.9 GO:0048785 hatching gland development(GO:0048785)
0.2 1.2 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.2 0.7 GO:0090171 cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554) chondrocyte morphogenesis(GO:0090171)
0.2 1.6 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.2 0.6 GO:0014005 regulation of cellular amino acid metabolic process(GO:0006521) microglia development(GO:0014005) regulation of cellular amine metabolic process(GO:0033238)
0.2 1.5 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.2 0.8 GO:1901492 regulation of lymphangiogenesis(GO:1901490) positive regulation of lymphangiogenesis(GO:1901492)
0.2 2.0 GO:0043584 nose development(GO:0043584)
0.2 1.8 GO:0019226 transmission of nerve impulse(GO:0019226)
0.2 0.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 0.6 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.2 0.7 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.2 2.3 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.2 0.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2 1.8 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.2 1.8 GO:0015671 oxygen transport(GO:0015671)
0.2 1.0 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.2 2.1 GO:0071698 olfactory placode development(GO:0071698)
0.2 1.1 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.2 0.5 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.2 2.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 1.0 GO:0070571 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.1 0.4 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 0.4 GO:1902871 negative regulation of photoreceptor cell differentiation(GO:0046533) regulation of amacrine cell differentiation(GO:1902869) positive regulation of amacrine cell differentiation(GO:1902871)
0.1 0.6 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.1 1.5 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.8 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.4 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 0.8 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 0.5 GO:1901998 toxin transport(GO:1901998)
0.1 1.1 GO:0034672 anterior/posterior pattern specification involved in pronephros development(GO:0034672) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.1 1.4 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 0.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 1.2 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.7 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.1 0.3 GO:0061614 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.1 0.9 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.1 0.7 GO:0090303 positive regulation of wound healing(GO:0090303)
0.1 0.8 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 4.7 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.1 1.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 1.0 GO:0061074 regulation of neural retina development(GO:0061074)
0.1 1.6 GO:0071711 basement membrane organization(GO:0071711)
0.1 1.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.5 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 0.9 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 1.7 GO:0039020 pronephric nephron tubule development(GO:0039020)
0.1 0.9 GO:0009435 NAD biosynthetic process(GO:0009435)
0.1 1.9 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.1 0.6 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.1 0.6 GO:0021754 facial nucleus development(GO:0021754)
0.1 1.5 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.2 GO:0051963 regulation of synapse assembly(GO:0051963) positive regulation of synapse assembly(GO:0051965)
0.1 1.0 GO:0006801 superoxide metabolic process(GO:0006801)
0.1 0.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.4 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 1.3 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.1 1.2 GO:0032526 response to retinoic acid(GO:0032526)
0.1 0.3 GO:0006574 valine catabolic process(GO:0006574)
0.1 1.4 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.8 GO:0032418 lysosome localization(GO:0032418)
0.1 0.5 GO:0051382 kinetochore assembly(GO:0051382)
0.1 4.2 GO:0006836 neurotransmitter transport(GO:0006836)
0.1 0.8 GO:0015696 ammonium transport(GO:0015696)
0.0 0.8 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.8 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.3 GO:0050768 negative regulation of neurogenesis(GO:0050768)
0.0 0.7 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.7 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.4 GO:0006956 complement activation(GO:0006956)
0.0 1.0 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 1.0 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.3 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.6 GO:0035675 neuromast hair cell development(GO:0035675)
0.0 1.0 GO:0007099 centriole replication(GO:0007099)
0.0 1.4 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.2 GO:0046292 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.0 0.5 GO:0060974 cell migration involved in heart formation(GO:0060974)
0.0 4.0 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.2 GO:0010990 SMAD protein complex assembly(GO:0007183) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.7 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 1.2 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.3 GO:0071248 cellular response to metal ion(GO:0071248)
0.0 1.2 GO:0010675 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.0 0.2 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.0 0.3 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.8 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.8 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 0.9 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 1.1 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.3 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) maintenance of protein localization in endoplasmic reticulum(GO:0035437) cellular response to sterol depletion(GO:0071501)
0.0 1.0 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.5 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.3 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 1.2 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.0 0.8 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.9 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 2.0 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.2 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 1.4 GO:0071560 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 0.7 GO:0030282 bone mineralization(GO:0030282)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:0007412 axon target recognition(GO:0007412)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.6 GO:0036269 swimming behavior(GO:0036269)
0.0 0.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.5 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.5 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.1 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.0 0.2 GO:0009409 response to cold(GO:0009409)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 1.2 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.4 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.5 GO:0032456 endocytic recycling(GO:0032456)
0.0 1.0 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 1.1 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.7 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 1.5 GO:0043484 regulation of RNA splicing(GO:0043484)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.3 1.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.3 1.0 GO:0071914 prominosome(GO:0071914)
0.3 1.8 GO:0005833 hemoglobin complex(GO:0005833) haptoglobin-hemoglobin complex(GO:0031838)
0.2 1.2 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.2 1.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.2 0.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.0 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.6 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 1.5 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 1.2 GO:0031209 SCAR complex(GO:0031209)
0.1 1.0 GO:0030677 nucleoid(GO:0009295) ribonuclease P complex(GO:0030677) mitochondrial nucleoid(GO:0042645)
0.1 0.7 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 3.9 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 0.8 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 0.4 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.5 GO:0030130 trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 0.4 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1 1.5 GO:0005861 troponin complex(GO:0005861)
0.1 1.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 2.0 GO:0031225 anchored component of membrane(GO:0031225)
0.1 2.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.4 GO:0016342 catenin complex(GO:0016342)
0.0 2.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.1 GO:0016459 myosin complex(GO:0016459)
0.0 1.7 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.2 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 6.3 GO:0043235 receptor complex(GO:0043235)
0.0 1.6 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 1.6 GO:0005814 centriole(GO:0005814)
0.0 0.7 GO:0071565 nBAF complex(GO:0071565)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 3.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.8 GO:0030018 Z disc(GO:0030018)
0.0 2.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 5.5 GO:0005887 integral component of plasma membrane(GO:0005887)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0008158 hedgehog receptor activity(GO:0008158)
0.5 1.4 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.4 1.1 GO:0005542 folic acid binding(GO:0005542) ammonia-lyase activity(GO:0016841)
0.3 1.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.3 1.9 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.3 1.0 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.3 1.6 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.3 1.4 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.3 0.8 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.3 1.8 GO:0031720 haptoglobin binding(GO:0031720)
0.2 1.0 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.2 0.7 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 1.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 0.9 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 1.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.2 0.9 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 1.9 GO:0005504 fatty acid binding(GO:0005504)
0.2 0.9 GO:0017040 ceramidase activity(GO:0017040)
0.2 0.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 0.7 GO:0016936 galactoside binding(GO:0016936)
0.2 2.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 0.9 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.2 0.8 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 1.0 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.6 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 1.2 GO:0017046 peptide hormone binding(GO:0017046)
0.1 1.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.0 GO:0004322 ferroxidase activity(GO:0004322) ferric iron binding(GO:0008199) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.5 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.1 5.9 GO:0019838 growth factor binding(GO:0019838)
0.1 1.1 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 2.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.3 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 2.0 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 4.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.1 1.6 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.1 3.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.1 1.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.2 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.1 0.3 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 1.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.4 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 1.7 GO:0019955 cytokine binding(GO:0019955)
0.1 1.1 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.7 GO:0050308 carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308)
0.0 0.1 GO:0051192 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.3 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.0 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 4.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.7 GO:0000976 transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0 33.5 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 1.7 GO:0044389 ubiquitin-like protein ligase binding(GO:0044389)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698) calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 1.7 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140) succinate transmembrane transporter activity(GO:0015141)
0.0 0.4 GO:0030276 clathrin binding(GO:0030276)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.2 GO:0019201 nucleotide kinase activity(GO:0019201)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 3.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 1.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 1.4 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 2.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 3.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.5 PID BMP PATHWAY BMP receptor signaling
0.0 4.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.8 PID E2F PATHWAY E2F transcription factor network
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.7 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.9 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.2 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.2 1.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 1.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.2 1.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 0.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 1.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 0.9 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 2.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 3.7 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 1.4 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.1 0.7 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.1 0.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 5.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 0.5 REACTOME BILE ACID AND BILE SALT METABOLISM Genes involved in Bile acid and bile salt metabolism
0.1 1.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 2.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere