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Results for nr1h4

Z-value: 0.67

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Transcription factors associated with nr1h4

Gene Symbol Gene ID Gene Info
ENSDARG00000057741 nuclear receptor subfamily 1, group H, member 4

Activity profile of nr1h4 motif

Sorted Z-values of nr1h4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of nr1h4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_+_27697056 0.59 ENSDART00000132070
vesicle-associated membrane protein 5
chr1_-_11002715 0.56 ENSDART00000090689
BRCA1-associated ATM activator 1
chr5_+_39885307 0.55 ENSDART00000051055
NADH dehydrogenase (ubiquinone) Fe-S protein 4, (NADH-coenzyme Q reductase)
chr23_+_22671069 0.54 ENSDART00000054337
G protein-coupled receptor 157
chr23_+_28882409 0.52 ENSDART00000078171
peroxisomal biogenesis factor 14
chr5_+_24569070 0.50 ENSDART00000012268
mitochondrial ribosomal protein L41
chr2_+_23004159 0.45 ENSDART00000123442
zgc:161973
chr5_-_68799483 0.42 ENSDART00000145966
mitogen-activated protein kinase-activated protein kinase 5
chr24_-_31394710 0.42 ENSDART00000169556
ATP-binding cassette, sub-family D (ALD), member 3a
chr25_-_16685648 0.42 ENSDART00000019413
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9a
chr18_+_46153484 0.40 ENSDART00000015034
biliverdin reductase B
chr7_-_58856734 0.40 ENSDART00000159285
HAUS augmin-like complex, subunit 6
chr12_-_25110065 0.40 ENSDART00000077188
cytochrome c oxidase subunit VIIa polypeptide 3
chr10_-_26240772 0.40 ENSDART00000131394
FH2 domain containing 3
chr12_+_22449611 0.39

chr14_+_10648299 0.39 ENSDART00000145776
zinc finger, DHHC-type containing 15b
chr7_-_58856862 0.38 ENSDART00000164104
HAUS augmin-like complex, subunit 6
chr22_-_11106940 0.37 ENSDART00000016873
ATPase, H+ transporting, lysosomal accessory protein 2
chr21_+_11943637 0.36 ENSDART00000141306
zgc:162344
chr9_-_34459799 0.36 ENSDART00000059955
immunoglobulin-like domain containing receptor 1b
chr22_+_24532560 0.35 ENSDART00000169847
WD repeat domain 47b
chr6_+_4068830 0.34 ENSDART00000130642
ENSDARG00000088225
chr15_+_29126271 0.33 ENSDART00000144546
si:ch211-137a8.2
chr11_+_24820942 0.32

chr19_+_2754903 0.32 ENSDART00000160533
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr5_-_68943600 0.31 ENSDART00000159851
MOB kinase activator 1A
chr12_-_14104939 0.31 ENSDART00000152742
bucky ball 2-like
chr23_+_22671035 0.30 ENSDART00000054337
G protein-coupled receptor 157
chr7_-_32708788 0.30 ENSDART00000113744
plakophilin 3b
chr23_-_42918086 0.29 ENSDART00000102328
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr21_-_2335024 0.28 ENSDART00000171645
si:ch73-299h12.9
chr7_-_58856806 0.28 ENSDART00000159285
HAUS augmin-like complex, subunit 6
chr16_+_9635202 0.28 ENSDART00000148699
ENSDARG00000095943
chr23_+_4315077 0.28 ENSDART00000008761
ADP-ribosylation factor-like 6 interacting protein 5b
chr5_-_68943821 0.28 ENSDART00000158956
MOB kinase activator 1A
chr17_-_17744885 0.27 ENSDART00000155261
SRA stem-loop interacting RNA binding protein
chr5_+_1164747 0.26 ENSDART00000129490
expressed sequence BC139872
chr2_-_6139833 0.26 ENSDART00000147509
si:ch211-284b7.3
chr12_-_26291790 0.26 ENSDART00000152941
ubiquitin specific peptidase 54b
chr24_+_26223767 0.26

chr12_-_25110150 0.26 ENSDART00000077188
cytochrome c oxidase subunit VIIa polypeptide 3
chr2_-_6139895 0.25 ENSDART00000147509
si:ch211-284b7.3
chr4_-_1809690 0.24

chr14_+_22778880 0.24 ENSDART00000164526
ecto-NOX disulfide-thiol exchanger 2
chr2_-_37299150 0.24 ENSDART00000137598
NAD kinase b
chr2_-_23003738 0.24 ENSDART00000115025
THAP domain containing 4
chr21_-_11943446 0.23 ENSDART00000142644
tubulin polyglutamylase complex subunit 2
chr20_-_10500595 0.23 ENSDART00000064112
glutaredoxin 5 homolog (S. cerevisiae)
chr20_+_39782876 0.23 ENSDART00000050729
HD domain containing 2
chr12_-_18292591 0.23 ENSDART00000078724
ATP synthase mitochondrial F1 complex assembly factor 2
chr21_+_11943609 0.23 ENSDART00000155426
ENSDART00000102463
zgc:162344
chr5_-_68664928 0.23 ENSDART00000073676
iron-sulfur cluster assembly 1
chr15_+_46129807 0.22 ENSDART00000153936
si:ch1073-340i21.2
chr2_+_10362661 0.22 ENSDART00000136018
NOL1/NOP2/Sun domain family, member 4
chr23_+_22671150 0.22 ENSDART00000054337
G protein-coupled receptor 157
chr8_+_33010788 0.22 ENSDART00000172672
angiopoietin-like 2b
chr16_-_24646282 0.22 ENSDART00000126274
si:ch211-79k12.2
chr23_+_20505691 0.21 ENSDART00000140219
solute carrier family 35 (GDP-fucose transporter), member C2
chr18_-_2989015 0.21 ENSDART00000159257
remodeling and spacing factor 1a
chr6_+_15018104 0.20 ENSDART00000063648
NCK adaptor protein 2b
chr2_-_42384993 0.19 ENSDART00000141358
apolipoprotein M
chr2_-_27996140 0.19 ENSDART00000097868
trimethylguanosine synthase 1
chr6_-_39633603 0.19 ENSDART00000104042
activating transcription factor 7b
chr4_-_3340315 0.19 ENSDART00000009076
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr11_+_5845373 0.19 ENSDART00000111374
NADH dehydrogenase (ubiquinone) Fe-S protein 7, (NADH-coenzyme Q reductase)
chr1_-_44239584 0.19 ENSDART00000137216
transmembrane protein 176
chr9_+_17415990 0.19 ENSDART00000112884
kelch repeat and BTB (POZ) domain containing 7
chr6_-_49512935 0.18 ENSDART00000166238
ribosomal protein, large P2
chr23_+_22313519 0.18

chr5_+_40235387 0.18 ENSDART00000147767
si:dkey-3h3.3
chr6_-_19132923 0.18

chr7_+_28881845 0.17 ENSDART00000138065
transmembrane protein with metallophosphoesterase domain
chr10_+_3728747 0.17

chr21_-_2334989 0.16 ENSDART00000171645
si:ch73-299h12.9
chr16_-_20506304 0.16 ENSDART00000134980
si:dkeyp-86h10.3
chr2_+_27996280 0.16 ENSDART00000126762
transmembrane protein 68
chr12_-_18459868 0.16

chr16_-_4940567 0.16 ENSDART00000149421
replication protein A2
chr7_+_38395803 0.16 ENSDART00000013394
mitochondrial carrier homolog 2
chr2_+_38279454 0.16 ENSDART00000076478
dehydrogenase/reductase (SDR family) member 1
chr21_-_32048768 0.16 ENSDART00000146079
methionine adenosyltransferase II, beta
chr19_-_27958005 0.15 ENSDART00000114301
si:ch211-152p11.4
chr7_-_24567002 0.14 ENSDART00000139455
family with sequence similarity 113
chr18_-_21199617 0.13 ENSDART00000060166
glutamic-oxaloacetic transaminase 2a, mitochondrial
chr10_-_26240909 0.13 ENSDART00000131394
FH2 domain containing 3
chr18_+_31038010 0.13 ENSDART00000163471
urate (5-hydroxyiso-) hydrolase a
chr11_-_18174 0.13 ENSDART00000167814
proline rich 13
chr15_-_44054313 0.13 ENSDART00000110112
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr15_+_30246345 0.13 ENSDART00000100214
nuclear fragile X mental retardation protein interacting protein 2
chr5_+_65267043 0.13 ENSDART00000161578
myomaker, myoblast fusion factor
chr7_-_40359613 0.12 ENSDART00000173670
ubiquitin protein ligase E3C
chr1_+_5948527 0.12 ENSDART00000138919
ubiquitin-conjugating enzyme E2F (putative)
chr7_-_8635989 0.12 ENSDART00000081620
ventral anterior homeobox 2
chr25_-_340711 0.11 ENSDART00000178866
ENSDARG00000107546
chr9_-_34459768 0.11 ENSDART00000059955
immunoglobulin-like domain containing receptor 1b
chr2_-_45838054 0.11 ENSDART00000125406
family with sequence similarity 102, member B, a
chr4_-_3340275 0.11 ENSDART00000009076
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr8_-_19311772 0.11 ENSDART00000138881
ENSDART00000010604
ral guanine nucleotide dissociation stimulator-like 1
chr9_+_48309684 0.11 ENSDART00000177287
ENSDART00000113883
ENSDARG00000041339
chr22_-_38321005 0.11 ENSDART00000015117
ELAV like neuron-specific RNA binding protein 2
chr18_+_17796754 0.10

chr22_+_24291724 0.10 ENSDART00000168169
coiled-coil domain containing 50
chr4_+_1680973 0.10 ENSDART00000149826
ENSDART00000166437
ENSDART00000031135
ENSDART00000172300
ENSDART00000067446
solute carrier family 38, member 4
chr5_-_24568752 0.10 ENSDART00000145061
patatin-like phospholipase domain containing 7b
chr6_+_40954138 0.10 ENSDART00000156660
POZ (BTB) and AT hook containing zinc finger 1
chr15_+_46093261 0.10

chr3_+_48362748 0.10 ENSDART00000157199
MKL/myocardin-like 2b
chr6_-_586251 0.10 ENSDART00000148867
ENSDART00000149414
ENSDART00000149248
lectin, galactoside-binding, soluble, 2b
chr7_+_5837533 0.10 ENSDART00000110813
histone 1, H4, like
chr13_-_7434672 0.10 ENSDART00000159453
H2A histone family, member Y2
chr22_+_24291633 0.09 ENSDART00000165618
coiled-coil domain containing 50
chr10_+_22043094 0.09 ENSDART00000035188
Kv channel interacting protein 1 b
chr9_-_29832812 0.09 ENSDART00000101177
SPRY domain containing 7b
chr7_-_8635687 0.09 ENSDART00000081620
ventral anterior homeobox 2
chr7_+_36267647 0.08 ENSDART00000173653
chromodomain helicase DNA binding protein 9
chr8_+_13757024 0.08

chr22_-_10509388 0.08 ENSDART00000131217
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr5_+_35186037 0.08 ENSDART00000127383
ENSDART00000022043
StAR-related lipid transfer (START) domain containing 8
chr12_+_34018417 0.08 ENSDART00000032821
cytohesin 1b
chr15_+_30246662 0.08 ENSDART00000100214
nuclear fragile X mental retardation protein interacting protein 2
chr5_-_28090077 0.08

chr7_+_29030304 0.07 ENSDART00000099327
RAB8B, member RAS oncogene family
chr25_+_32062428 0.07 ENSDART00000152326
sulfide quinone reductase-like (yeast)
chr8_+_7297420 0.07 ENSDART00000140874
selenoprotein H
chr25_-_23949331 0.07 ENSDART00000047569
insulin-like growth factor 2b
chr16_-_4940519 0.06 ENSDART00000149421
replication protein A2
chr16_+_5284778 0.06 ENSDART00000156685
ENSDART00000156765
SOGA family member 3a
SOGA family member 3a
chr1_-_44002772 0.06 ENSDART00000133210
si:dkey-28b4.8
chr19_-_19282688 0.06 ENSDART00000162708
palmitoyl-protein thioesterase 2
chr15_+_21231406 0.06 ENSDART00000038499
ENSDARG00000077872
chr8_+_45934564 0.06 ENSDART00000060955
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr20_-_49965261 0.05

chr18_+_46153538 0.05 ENSDART00000114128
biliverdin reductase B
chr1_+_127240 0.05 ENSDART00000122230
coagulation factor VIIi
chr4_-_18466436 0.05 ENSDART00000150221
SCO2 cytochrome c oxidase assembly protein
chr8_+_13069019 0.05 ENSDART00000167926
integrin, beta 4
chr25_+_23494481 0.05 ENSDART00000089199
carnitine palmitoyltransferase 1Ab (liver)
chr17_+_794430 0.04 ENSDART00000158830
cytochrome P450, family 1, subfamily C, polypeptide 2
chr13_-_25066650 0.04

chr1_+_44239727 0.04 ENSDART00000141145
si:dkey-9i23.16
chr14_-_29542922 0.04

chr15_+_24756002 0.04 ENSDART00000110618
leucine rich repeat containing 75A
chr4_+_8531280 0.04 ENSDART00000162065
wingless-type MMTV integration site family, member 5b
chr16_+_36465373 0.04 ENSDART00000158358
serine/threonine kinase 40
chr23_+_20505072 0.04 ENSDART00000132920
solute carrier family 35 (GDP-fucose transporter), member C2
chr6_-_31160132 0.04 ENSDART00000153592
ENSDARG00000097226
chr22_-_10509348 0.03 ENSDART00000131217
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr6_+_38629054 0.03 ENSDART00000086533
ATPase, class V, type 10A
chr3_-_19750156 0.03 ENSDART00000134969
Rho family GTPase 2
chr3_+_31821397 0.03 ENSDART00000148861
potassium voltage-gated channel, Shaw-related subfamily, member 3a
chr23_+_20505319 0.03 ENSDART00000140219
solute carrier family 35 (GDP-fucose transporter), member C2
chr10_+_37033 0.03 ENSDART00000157786
ribosomal oxygenase 2
chr3_-_32192499 0.03

chr23_-_42918055 0.03 ENSDART00000102328
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr5_-_45986774 0.02

chr4_+_8531350 0.02 ENSDART00000162065
wingless-type MMTV integration site family, member 5b
chr22_+_24532479 0.02 ENSDART00000169847
WD repeat domain 47b
chr10_+_16634200 0.02 ENSDART00000101142
chondroitin sulfate synthase 3
chr19_-_32487376 0.02

chr14_-_33936261 0.02 ENSDART00000021437
glutamate receptor, ionotropic, AMPA 1a
chr6_-_40314512 0.02 ENSDART00000033844
collagen, type VII, alpha 1
chr2_+_43757541 0.01

chr12_+_16848206 0.01

chr16_+_36465436 0.01 ENSDART00000158358
serine/threonine kinase 40
chr15_-_30247084 0.00 ENSDART00000154069
ENSDARG00000097908

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.1 0.2 GO:0007624 ultradian rhythm(GO:0007624)
0.1 0.4 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.3 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.1 0.2 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.6 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0006531 aspartate metabolic process(GO:0006531)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.1 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.2 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.4 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.4 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.0 0.1 GO:0052746 inositol phosphorylation(GO:0052746)
0.0 0.1 GO:0009155 purine deoxyribonucleotide catabolic process(GO:0009155)
0.0 0.2 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259) negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.0 0.2 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 1.1 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.6 GO:0010212 response to ionizing radiation(GO:0010212)
0.0 0.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0014896 regulation of muscle hypertrophy(GO:0014743) muscle hypertrophy(GO:0014896)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.2 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.4 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.5 GO:0022900 electron transport chain(GO:0022900)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.1 GO:0070652 HAUS complex(GO:0070652)
0.1 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0030552 cAMP binding(GO:0030552)
0.1 0.2 GO:0048270 methionine adenosyltransferase regulator activity(GO:0048270)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.3 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.1 GO:0033971 hydroxyisourate hydrolase activity(GO:0033971)
0.0 0.4 GO:0015245 long-chain fatty acid transporter activity(GO:0005324) fatty acid transporter activity(GO:0015245)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.7 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.0 0.2 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport