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Results for nr2c1

Z-value: 0.28

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Transcription factors associated with nr2c1

Gene Symbol Gene ID Gene Info
nr2c1
ENSDARG00000045527 nuclear receptor subfamily 2, group C, member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr2c1dr10_dc_chr4_-_25869361_25869450-0.543.1e-02Click!

Activity profile of nr2c1 motif

Sorted Z-values of nr2c1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of nr2c1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr17_+_23463072 0.63

chr10_-_21404605 0.50 ENSDART00000125167
avd
avidin
chr22_+_132285 0.49 ENSDART00000059140
slc25a20
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
chr4_-_17028492 0.42

chr7_+_13742576 0.41

chr11_+_37345493 0.36 ENSDART00000157993
hp1bp3
heterochromatin protein 1, binding protein 3
chr10_-_180603 0.36

chr7_+_13742622 0.36

chr12_+_31623806 0.33

chr10_+_15382647 0.33 ENSDART00000046274
trappc13
trafficking protein particle complex 13
chr4_-_7867294 0.32 ENSDART00000167943
nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr3_-_18655432 0.31 ENSDART00000034489
msrb1a
methionine sulfoxide reductase B1a
chr7_+_34025638 0.30 ENSDART00000052471
ENSDART00000173798
bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr22_-_58352 0.29 ENSDART00000127829
atad3
ATPase family, AAA domain containing 3
chr11_+_24076334 0.29 ENSDART00000017599
rem1
RAS (RAD and GEM)-like GTP-binding 1
chr11_+_24820942 0.29

chr23_+_42793279 0.29

chr15_+_29126271 0.29 ENSDART00000144546
si:ch211-137a8.2
si:ch211-137a8.2
chr3_-_58400454 0.28 ENSDART00000052179
cdr2a
cerebellar degeneration-related protein 2a
chr25_+_32419008 0.27

chr5_+_3683209 0.27 ENSDART00000132056
ggnbp2
gametogenetin binding protein 2
chr3_-_32795702 0.27 ENSDART00000140117
aoc2
amine oxidase, copper containing 2
chr6_-_31798839 0.26

chr8_+_10825036 0.25 ENSDART00000140717
brpf3b
bromodomain and PHD finger containing, 3b
chr13_+_7243353 0.25 ENSDART00000146592
gbf1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr19_+_3115642 0.24 ENSDART00000127473
ENSDART00000126549
ENSDART00000024593
ENSDART00000082353
ENSDART00000141324
hsf1
heat shock transcription factor 1
chr3_-_33362324 0.24 ENSDART00000020342
sgsm3
small G protein signaling modulator 3
chr10_-_41018185 0.24 ENSDART00000134295
bmp1b
bone morphogenetic protein 1b
chr4_-_7867110 0.23 ENSDART00000162276
nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr17_+_25828037 0.23

chr2_-_41888389 0.22

chr5_+_56658275 0.22 ENSDART00000149646
slc31a1
solute carrier family 31 (copper transporter), member 1
chr3_-_58400345 0.22 ENSDART00000052179
cdr2a
cerebellar degeneration-related protein 2a
chr14_+_971438 0.22 ENSDART00000161487
si:ch73-308l14.2
si:ch73-308l14.2
chr4_-_951763 0.22 ENSDART00000093289
xrcc6bp1
XRCC6 binding protein 1
chr24_-_12622124 0.21

chr23_+_39454172 0.20 ENSDART00000149819
src
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr19_-_22761674 0.20

chr3_+_27639256 0.20 ENSDART00000017962
eci1
enoyl-CoA delta isomerase 1
chr11_-_37656066 0.20

chr1_-_40536800 0.20 ENSDART00000134739
rgs12b
regulator of G protein signaling 12b
chr10_-_41018394 0.19 ENSDART00000059795
bmp1b
bone morphogenetic protein 1b
chr3_+_25904651 0.19 ENSDART00000078137
ankrd54
ankyrin repeat domain 54
chr12_+_31668126 0.19 ENSDART00000105584
lrrc59
leucine rich repeat containing 59
chr10_-_180681 0.19

chr4_-_16461881 0.18 ENSDART00000128835
wu:fc23c09
wu:fc23c09
chr13_+_583640 0.18 ENSDART00000109737
cox15
cytochrome c oxidase assembly homolog 15 (yeast)
chr21_+_2728070 0.18

chr11_+_24076576 0.18 ENSDART00000171491
rem1
RAS (RAD and GEM)-like GTP-binding 1
chr10_+_15382807 0.18 ENSDART00000168909
trappc13
trafficking protein particle complex 13
chr19_+_3115514 0.18 ENSDART00000127473
ENSDART00000126549
ENSDART00000024593
ENSDART00000082353
ENSDART00000141324
hsf1
heat shock transcription factor 1
chr5_-_45986774 0.18

chr6_+_40525779 0.17 ENSDART00000033819
prkcda
protein kinase C, delta a
chr8_-_2471264 0.17 ENSDART00000056767
acaa2
acetyl-CoA acyltransferase 2
chr20_-_36768848 0.17 ENSDART00000134819
slc5a6a
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6a
chr13_+_33545847 0.16 ENSDART00000023379
mgme1
mitochondrial genome maintenance exonuclease 1
chr12_+_31668168 0.16 ENSDART00000105584
lrrc59
leucine rich repeat containing 59
chr16_-_25765512 0.16 ENSDART00000132693
tomm40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr17_-_20110496 0.16

chr19_-_3115104 0.16 ENSDART00000093146
bop1
block of proliferation 1
chr8_+_10824974 0.16 ENSDART00000140717
brpf3b
bromodomain and PHD finger containing, 3b
chr3_-_33362384 0.16 ENSDART00000020342
sgsm3
small G protein signaling modulator 3
chr13_+_7243325 0.15 ENSDART00000146592
gbf1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr16_-_25765396 0.15 ENSDART00000132693
tomm40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr24_+_14095601 0.15 ENSDART00000124740
ncoa2
nuclear receptor coactivator 2
chr23_+_39453929 0.15 ENSDART00000102843
src
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr5_+_26804676 0.15 ENSDART00000121886
ENSDART00000005025
hdr
hematopoietic death receptor
chr8_+_21127033 0.15 ENSDART00000033491
spryd4
SPRY domain containing 4
chr16_-_25765322 0.15 ENSDART00000132693
tomm40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr13_+_6908853 0.15 ENSDART00000109434
aifm2
apoptosis-inducing factor, mitochondrion-associated, 2
chr25_-_27222696 0.14 ENSDART00000123590
si:ch211-91p5.3
si:ch211-91p5.3
chr5_-_41260390 0.14 ENSDART00000140154
si:dkey-65b12.12
si:dkey-65b12.12
chr15_+_40228295 0.14 ENSDART00000111018
ngef
neuronal guanine nucleotide exchange factor
chr9_+_33179226 0.14

chr19_-_6503643 0.14

chr3_+_40147509 0.14 ENSDART00000017304
cpsf4
cleavage and polyadenylation specific factor 4
chr2_+_32033176 0.13 ENSDART00000135040
mycb
MYC proto-oncogene, bHLH transcription factor b
chr23_+_37380022 0.13 ENSDART00000162737
agmat
agmatine ureohydrolase (agmatinase)
chr5_+_56658431 0.13 ENSDART00000149646
slc31a1
solute carrier family 31 (copper transporter), member 1
chr12_+_19016508 0.13 ENSDART00000141346
ENSDART00000066397
phf5a
PHD finger protein 5A
chr16_+_36794641 0.12 ENSDART00000139069
decr1
2,4-dienoyl CoA reductase 1, mitochondrial
chr3_+_19186724 0.12 ENSDART00000110548
kri1
KRI1 homolog
chr8_-_8659980 0.12 ENSDART00000046712
zgc:86609
zgc:86609
chr16_-_25765583 0.12 ENSDART00000132693
tomm40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr11_-_43125936 0.12

chr11_+_24076371 0.12 ENSDART00000166045
rem1
RAS (RAD and GEM)-like GTP-binding 1
chr21_-_43176006 0.11 ENSDART00000148630
hspa4a
heat shock protein 4a
chr24_+_17055519 0.11 ENSDART00000149954
mllt10
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10
chr3_-_36277628 0.11 ENSDART00000173545
cog1
component of oligomeric golgi complex 1
chr23_+_22671035 0.11 ENSDART00000054337
gpr157
G protein-coupled receptor 157
chr20_+_28506477 0.11 ENSDART00000114929
zfyve1
zinc finger, FYVE domain containing 1
chr5_-_22090397 0.10

chr3_+_19186494 0.10 ENSDART00000111528
kri1
KRI1 homolog
chr23_+_22671150 0.10 ENSDART00000054337
gpr157
G protein-coupled receptor 157
chr3_-_36277758 0.10 ENSDART00000173545
cog1
component of oligomeric golgi complex 1
chr16_-_25765542 0.09 ENSDART00000132693
tomm40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr11_-_35757903 0.09 ENSDART00000167472
itpr1b
inositol 1,4,5-trisphosphate receptor, type 1b
chr8_+_10824790 0.09 ENSDART00000140717
brpf3b
bromodomain and PHD finger containing, 3b
chr15_-_1880173 0.09 ENSDART00000154175
taf15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr14_+_30073402 0.09 ENSDART00000136009
cnot7
CCR4-NOT transcription complex, subunit 7
chr4_-_951970 0.09 ENSDART00000093289
xrcc6bp1
XRCC6 binding protein 1
chr25_-_18910254 0.09 ENSDART00000019765
efcab6
EF-hand calcium binding domain 6
chr1_-_51086075 0.09 ENSDART00000045894
rnaseh2a
ribonuclease H2, subunit A
chr9_-_41982745 0.09 ENSDART00000144573
obsl1b
obscurin-like 1b
chr16_-_25765623 0.08 ENSDART00000015302
tomm40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr7_-_65913414 0.08 ENSDART00000145843
pth1b
parathyroid hormone 1b
chr12_-_22387786 0.08 ENSDART00000109707
neurl4
neuralized E3 ubiquitin protein ligase 4
chr2_+_6155429 0.08 ENSDART00000145244
aldh9a1b
aldehyde dehydrogenase 9 family, member A1b
chr5_-_22090338 0.08

chr5_-_30112312 0.08

chr6_+_40954342 0.07

chr25_+_18910528 0.07 ENSDART00000104420
samm50
SAMM50 sorting and assembly machinery component
chr11_+_3479741 0.07 ENSDART00000171621
pusl1
pseudouridylate synthase-like 1
chr17_+_16600773 0.07

chr23_+_22671069 0.07 ENSDART00000054337
gpr157
G protein-coupled receptor 157
chr17_+_28664644 0.07

chr2_-_4276017 0.07

chr10_-_20148585 0.07 ENSDART00000138120
ENSDART00000079922
pbdc1
polysaccharide biosynthesis domain containing 1
chr20_-_36768780 0.07 ENSDART00000134819
slc5a6a
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6a
chr8_+_2471513 0.07 ENSDART00000063943
mrpl40
mitochondrial ribosomal protein L40
chr19_-_35117708 0.06

chr17_-_49324003 0.06 ENSDART00000021950
mthfd1b
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr3_+_53792981 0.06 ENSDART00000178486
olfm2a
olfactomedin 2a
chr9_+_17421457 0.05 ENSDART00000006256
zgc:101559
zgc:101559
chr1_+_54059634 0.05 ENSDART00000162075
pi4k2a
phosphatidylinositol 4-kinase type 2 alpha
chr6_+_40525610 0.05 ENSDART00000033819
prkcda
protein kinase C, delta a
chr12_+_26579286 0.05 ENSDART00000144355
arhgap12b
Rho GTPase activating protein 12b
chr15_+_28335293 0.05 ENSDART00000152536
myo1cb
myosin Ic, paralog b
chr16_+_8067533 0.05 ENSDART00000126041
ano10a
anoctamin 10a
chr7_+_41871444 0.04 ENSDART00000149250
phkb
phosphorylase kinase, beta
chr2_-_4275952 0.04

chr8_+_8660457 0.04 ENSDART00000137780
uxt
ubiquitously-expressed, prefoldin-like chaperone
chr6_-_39905773 0.04 ENSDART00000148612
tsfm
Ts translation elongation factor, mitochondrial
chr3_+_25904908 0.04 ENSDART00000078137
ankrd54
ankyrin repeat domain 54
chr9_+_38692733 0.04 ENSDART00000087229
lmln
leishmanolysin-like (metallopeptidase M8 family)
chr20_+_38717757 0.04 ENSDART00000144521
si:ch211-243j20.2
si:ch211-243j20.2
chr20_-_27038165 0.04 ENSDART00000160827
ftr79
finTRIM family, member 79
chr10_-_8238422 0.04 ENSDART00000129467
dhx29
DEAH (Asp-Glu-Ala-His) box polypeptide 29
chr3_+_32539409 0.03 ENSDART00000136292
rnf25
ring finger protein 25
chr6_-_51541332 0.03 ENSDART00000156336
ENSDART00000154512
si:dkey-6e2.2
si:dkey-6e2.2
chr21_-_1956120 0.03 ENSDART00000165547
CABZ01045062.1
ENSDARG00000100274
chr14_-_6818814 0.03

chr7_+_31567140 0.03 ENSDART00000144679
mybpc3
myosin binding protein C, cardiac
chr18_-_16934961 0.03 ENSDART00000122102
wee1
WEE1 G2 checkpoint kinase
chr17_-_22117248 0.02 ENSDART00000089689
mrps5
mitochondrial ribosomal protein S5
chr11_+_6450876 0.02 ENSDART00000170180
CU062501.2
ENSDARG00000103967
chr15_-_1880375 0.02 ENSDART00000102410
taf15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr23_+_20184837 0.02

chr1_-_43880612 0.02 ENSDART00000009858
tmx2b
thioredoxin-related transmembrane protein 2b
chr13_-_37002066 0.02 ENSDART00000135510
syne2b
spectrin repeat containing, nuclear envelope 2b
chr15_+_40228075 0.02 ENSDART00000111018
ngef
neuronal guanine nucleotide exchange factor
chr24_+_30852751 0.02

chr23_+_17946764 0.01 ENSDART00000117743
SNORD59
Small nucleolar RNA SNORD59
chr15_+_36355348 0.01

chr24_+_17055672 0.01 ENSDART00000149954
mllt10
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10
chr9_+_34623833 0.01 ENSDART00000175455
si:ch211-269e2.1
si:ch211-269e2.1
chr21_-_1956163 0.01 ENSDART00000165547
CABZ01045062.1
ENSDARG00000100274
chr17_-_21348828 0.01 ENSDART00000058027
shtn1
shootin 1
chr2_-_55970982 0.01 ENSDART00000154701
ENSDART00000154107
si:ch211-178n15.1
si:ch211-178n15.1
chr4_-_16461748 0.00 ENSDART00000128835
wu:fc23c09
wu:fc23c09
chr10_-_20545884 0.00

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0098751 bone cell development(GO:0098751)
0.1 0.6 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.4 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.2 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.1 0.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.5 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.2 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.4 GO:0070828 heterochromatin organization(GO:0070828)
0.0 0.1 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.0 0.3 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579) positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 0.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.4 GO:0009408 response to heat(GO:0009408)
0.0 0.0 GO:0070125 mitochondrial translational elongation(GO:0070125)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.1 0.8 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.0 GO:0005964 phosphorylase kinase complex(GO:0005964)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.1 0.5 GO:0009374 biotin binding(GO:0009374)
0.1 0.5 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 0.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.2 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.2 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.5 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.8 GO:0022884 protein transmembrane transporter activity(GO:0008320) macromolecule transmembrane transporter activity(GO:0022884)
0.0 0.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.1 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.3 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0043878 aminobutyraldehyde dehydrogenase activity(GO:0019145) glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.2 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.2 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines