Project

DANIO-CODE

Navigation
Downloads

Results for nr2e3

Z-value: 1.83

Motif logo

logo of

Transcription factors associated with nr2e3

Gene Symbol Gene ID Gene Info
nr2e3
ENSDARG00000045904 nuclear receptor subfamily 2, group E, member 3

Activity profile of nr2e3 motif

Sorted Z-values of nr2e3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of nr2e3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr8_+_47644421 6.81 ENSDART00000139096
si:ch211-251b21.1
si:ch211-251b21.1
chr19_+_41396014 5.46 ENSDART00000159444
ENSDART00000042990
ENSDART00000144544
col1a2
collagen, type I, alpha 2
chr16_+_26900732 4.53 ENSDART00000042895
cdh17
cadherin 17, LI cadherin (liver-intestine)
chr1_+_25662652 4.45 ENSDART00000113020
tet2
tet methylcytosine dioxygenase 2
chr4_+_12033088 4.28 ENSDART00000044154
tnnt2c
troponin T2c, cardiac
chr3_+_26896869 4.23 ENSDART00000065495
emp2
epithelial membrane protein 2
chr3_-_27516974 4.20 ENSDART00000151675
si:ch211-157c3.4
si:ch211-157c3.4
chr23_-_511984 4.00 ENSDART00000055139
col9a3
collagen, type IX, alpha 3
chr10_+_4717800 3.93 ENSDART00000161789
palm2
paralemmin 2
chr18_+_43041488 3.91

chr7_+_44373815 3.79 ENSDART00000170721
si:dkey-56m19.5
si:dkey-56m19.5
chr12_+_25509394 3.78 ENSDART00000077157
six3b
SIX homeobox 3b
chr8_+_21163236 3.68 ENSDART00000091307
col2a1a
collagen, type II, alpha 1a
chr3_-_39313029 3.56 ENSDART00000156123
CU464118.1
ENSDARG00000097747
chr18_+_40364675 3.51 ENSDART00000098791
ENSDART00000049171
sema6dl
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr20_+_4567653 3.42

chr2_-_8219329 3.41 ENSDART00000040209
ephb3a
eph receptor B3a
chr12_+_42281025 3.41 ENSDART00000167324
ebf3a
early B-cell factor 3a
chr12_-_37560192 3.37 ENSDART00000140353
sdk2b
sidekick cell adhesion molecule 2b
chr21_-_8103907 3.27 ENSDART00000171027
OLFML2A
olfactomedin like 2A
chr14_-_46651359 3.11 ENSDART00000163316
CR383676.1
ENSDARG00000099970
chr24_-_12794057 3.09 ENSDART00000024084
pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr24_-_28814066 3.07 ENSDART00000042065
ENSDART00000170675
ENSDART00000158668
col11a1a
collagen, type XI, alpha 1a
chr3_+_53518347 3.07 ENSDART00000170461
col5a3a
collagen, type V, alpha 3a
chr4_-_8610868 2.87 ENSDART00000067322
fbxl14b
F-box and leucine-rich repeat protein 14b
chr12_-_25796463 2.87 ENSDART00000152983
si:dkey-193p11.2
si:dkey-193p11.2
chr4_-_73485204 2.81 ENSDART00000122898
phf21b
PHD finger protein 21B
chr9_+_25520011 2.75 ENSDART00000167110
itm2bb
integral membrane protein 2Bb
chr25_+_21732255 2.67 ENSDART00000027393
ckmt1
creatine kinase, mitochondrial 1
chr3_+_28450576 2.65 ENSDART00000150893
sept12
septin 12
chr12_-_30662709 2.64 ENSDART00000126466
entpd1
ectonucleoside triphosphate diphosphohydrolase 1
chr14_-_42633578 2.63 ENSDART00000162714
ENSDART00000161521
pcdh10b
protocadherin 10b
chr7_-_18302231 2.60 ENSDART00000108938
msantd1
Myb/SANT-like DNA-binding domain containing 1
chr24_-_12794564 2.60 ENSDART00000024084
pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr6_-_47842137 2.58 ENSDART00000141986
lrig2
leucine-rich repeats and immunoglobulin-like domains 2
chr1_-_46052304 2.54 ENSDART00000142880
BX294379.1
ENSDARG00000092950
chr24_-_34449257 2.53 ENSDART00000128690
agap3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr3_-_34671480 2.51 ENSDART00000167355
nsfa
N-ethylmaleimide-sensitive factor a
chr2_+_22324846 2.50 ENSDART00000044371
tox
thymocyte selection-associated high mobility group box
chr1_-_35419335 2.49 ENSDART00000037516
znf827
zinc finger protein 827
chr5_+_42406222 2.46 ENSDART00000009182
aqp3a
aquaporin 3a
chr22_+_26543146 2.46

chr19_+_156649 2.46 ENSDART00000167717
lrrc16a
leucine rich repeat containing 16A
chr12_+_31501522 2.46 ENSDART00000144422
cpn1
carboxypeptidase N, polypeptide 1
chr7_+_21455138 2.45 ENSDART00000173992
kdm6ba
lysine (K)-specific demethylase 6B, a
chr1_-_22160662 2.44 ENSDART00000054386
qdprb1
quinoid dihydropteridine reductase b1
chr5_+_38487183 2.44 ENSDART00000164065
anxa3a
annexin A3a
chr4_-_20435099 2.40 ENSDART00000055317
lrrc17
leucine rich repeat containing 17
chr21_-_26459113 2.39 ENSDART00000157255
cd248b
CD248 molecule, endosialin b
chr12_+_24833569 2.35 ENSDART00000014868
calm3a
calmodulin 3a (phosphorylase kinase, delta)
chr12_-_25973094 2.34 ENSDART00000171206
ENSDART00000171212
ENSDART00000170265
ldb3b
LIM domain binding 3b
chr9_+_49054601 2.34 ENSDART00000047401
abcb11a
ATP-binding cassette, sub-family B (MDR/TAP), member 11a
chr24_+_19842162 2.32 ENSDART00000123031
CR381686.3
ENSDARG00000094073
chr11_-_18542803 2.31 ENSDART00000059732
id1
inhibitor of DNA binding 1
chr16_-_9978112 2.30 ENSDART00000149312
ncalda
neurocalcin delta a
chr9_-_30437160 2.29 ENSDART00000147241
BX936337.1
ENSDARG00000092870
chr5_-_33006537 2.23 ENSDART00000048350
si:dkey-34e4.1
si:dkey-34e4.1
chr8_-_15091823 2.22 ENSDART00000142358
bcar3
breast cancer anti-estrogen resistance 3
chr8_+_15989815 2.22 ENSDART00000110171
elavl4
ELAV like neuron-specific RNA binding protein 4
chr1_-_10822278 2.18 ENSDART00000091205
sdk1b
sidekick cell adhesion molecule 1b
chr19_+_20209561 2.18 ENSDART00000168833
CR382300.1
ENSDARG00000098798
chr14_-_46650724 2.15

chr11_-_7310284 2.13 ENSDART00000091664
apc2
adenomatosis polyposis coli 2
chr17_-_35934175 2.13 ENSDART00000110040
ENSDART00000137525
sox11a
AL929378.1
SRY (sex determining region Y)-box 11a
ENSDARG00000092907
chr24_-_26334717 2.12 ENSDART00000079984
ENSDART00000136871
rpl22l1
ribosomal protein L22-like 1
chr23_-_28560598 2.11 ENSDART00000127072
tmem107l
transmembrane protein 107 like
chr2_+_36634309 2.10 ENSDART00000169547
ENSDART00000098417
pak2a
p21 protein (Cdc42/Rac)-activated kinase 2a
chr1_+_46537108 2.10

chr15_-_4537178 2.09 ENSDART00000155619
ENSDART00000128602
tfdp2
transcription factor Dp-2
chr7_-_35438739 2.09 ENSDART00000043857
irx5a
iroquois homeobox 5a
chr3_-_32727588 2.08 ENSDART00000158916
si:dkey-16l2.20
si:dkey-16l2.20
chr24_+_24308055 2.06

chr14_+_21563827 2.05 ENSDART00000032141
spon2a
spondin 2a, extracellular matrix protein
chr5_+_59845054 2.01 ENSDART00000130565
tmem132e
transmembrane protein 132E
chr7_-_8128948 2.00 ENSDART00000057101
aep1
aerolysin-like protein
chr13_+_22528640 1.96 ENSDART00000078877
sncga
synuclein, gamma a
chr8_-_33372638 1.96 ENSDART00000076420
lmx1bb
LIM homeobox transcription factor 1, beta b
KN149932v1_+_27584 1.96

chr17_-_14551031 1.96 ENSDART00000162452
daam1a
dishevelled associated activator of morphogenesis 1a
chr17_+_134921 1.96 ENSDART00000166339
klhdc2
kelch domain containing 2
chr9_+_31471391 1.95 ENSDART00000010774
zic2a
zic family member 2 (odd-paired homolog, Drosophila), a
chr20_+_34679181 1.95

chr3_+_36155364 1.95 ENSDART00000059533
wipi1
WD repeat domain, phosphoinositide interacting 1
chr17_+_27417635 1.93 ENSDART00000052446
vgll2b
vestigial-like family member 2b
chr7_+_63014869 1.92 ENSDART00000161436
pcdh7b
protocadherin 7b
chr7_-_46509291 1.92 ENSDART00000173891
tshz3b
teashirt zinc finger homeobox 3b
chr22_+_18222691 1.88 ENSDART00000148357
BX664610.1
ENSDARG00000095557
chr24_+_39266257 1.86 ENSDART00000053139
atp6v0cb
ATPase, H+ transporting, lysosomal, V0 subunit cb
chr20_-_9992898 1.86 ENSDART00000080664
ACTC1
zgc:86709
chr18_+_40365208 1.86 ENSDART00000167134
sema6dl
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr5_+_37662896 1.86 ENSDART00000051231
gnb2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr5_-_62816208 1.85 ENSDART00000097325
c5
complement component 5
chr20_+_35010140 1.84 ENSDART00000172001
snap25a
synaptosomal-associated protein, 25a
chr25_-_12107407 1.83 ENSDART00000159800
ENSDART00000091727
ntrk3a
neurotrophic tyrosine kinase, receptor, type 3a
chr8_+_25748377 1.83 ENSDART00000062406
cacna1sb
calcium channel, voltage-dependent, L type, alpha 1S subunit, b
chr19_-_22983970 1.82 ENSDART00000160153
pleca
plectin a
KN150170v1_+_10738 1.82 ENSDART00000159076
HUS1
HUS1 checkpoint clamp component
chr23_-_15807415 1.80 ENSDART00000178557
BX005011.3
ENSDARG00000108083
chr1_-_18110990 1.80 ENSDART00000020970
pgm2
phosphoglucomutase 2
chr19_-_22182031 1.78 ENSDART00000104279
znf516
zinc finger protein 516
chr7_-_14937467 1.77 ENSDART00000031049
ENSDARG00000023868
ENSDARG00000023868
chr5_+_59844830 1.76 ENSDART00000130565
tmem132e
transmembrane protein 132E
chr11_+_37639045 1.74 ENSDART00000111157
si:ch211-112f3.4
si:ch211-112f3.4
chr6_-_12079553 1.74 ENSDART00000157058
si:dkey-276j7.1
si:dkey-276j7.1
chr19_+_20202737 1.70 ENSDART00000164677
hoxa4a
homeobox A4a
chr15_+_14048904 1.70 ENSDART00000159438
zgc:162730
zgc:162730
chr7_+_19310071 1.70 ENSDART00000077545
slc7a7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr20_+_4567603 1.68

chr9_-_22394674 1.67 ENSDART00000101869
crygm2d12
crystallin, gamma M2d12
chr3_-_34363698 1.67

chr7_-_21978889 1.62

chr4_+_22020246 1.62 ENSDART00000112035
ENSDART00000127664
myf5
myogenic factor 5
chr16_+_5625301 1.62

chr4_+_10722966 1.62 ENSDART00000102534
ENSDART00000067253
ENSDART00000136000
stab2
stabilin 2
chr9_-_22377136 1.61 ENSDART00000110933
CR847505.1
ENSDARG00000076693
chr14_+_23917724 1.61 ENSDART00000138082
ENSDART00000079215
stc2a
stanniocalcin 2a
chr1_-_11163480 1.60 ENSDART00000033361
ttyh3b
tweety family member 3b
chr21_+_22808694 1.60 ENSDART00000065555
birc2
baculoviral IAP repeat containing 2
chr17_+_48734060 1.56 ENSDART00000178697
daam2
dishevelled associated activator of morphogenesis 2
chr1_-_53403731 1.56 ENSDART00000171722
smdt1b
single-pass membrane protein with aspartate-rich tail 1b
chr3_-_28534446 1.56 ENSDART00000151670
fbxl16
F-box and leucine-rich repeat protein 16
chr24_-_12794672 1.55 ENSDART00000024084
pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr6_-_35326559 1.55 ENSDART00000114960
nos1apa
nitric oxide synthase 1 (neuronal) adaptor protein a
chr16_+_53178713 1.54 ENSDART00000174634
CABZ01062546.1
ENSDARG00000108858
chr21_-_20305406 1.54 ENSDART00000065659
rbp4l
retinol binding protein 4, like
chr5_+_68410884 1.53 ENSDART00000153691
CU928129.1
ENSDARG00000097815
chr19_-_22904687 1.53 ENSDART00000141503
pleca
plectin a
chr24_-_38899781 1.53 ENSDART00000112318
ntn2
netrin 2
chr14_-_6822151 1.51 ENSDART00000171311
si:ch73-43g23.1
si:ch73-43g23.1
chr9_-_6683651 1.50 ENSDART00000061593
pou3f3a
POU class 3 homeobox 3a
chr20_+_13998066 1.48 ENSDART00000007744
slc30a1a
solute carrier family 30 (zinc transporter), member 1a
chr4_-_73484546 1.48

chr2_-_41669008 1.48 ENSDART00000130830
otomp
otolith matrix protein
chr3_-_33295814 1.47 ENSDART00000146294
rpl23
ribosomal protein L23
chr8_+_18552850 1.46 ENSDART00000177476
prrg1
proline rich Gla (G-carboxyglutamic acid) 1
chr15_+_30276801 1.45 ENSDART00000047248
ENSDART00000123937
nlk2
nemo-like kinase, type 2
chr6_-_36574848 1.44 ENSDART00000135413
her6
hairy-related 6
chr5_-_40451061 1.43 ENSDART00000083515
pdzd2
PDZ domain containing 2
chr4_-_73485028 1.42 ENSDART00000122898
phf21b
PHD finger protein 21B
chr3_+_56008829 1.41

chr17_+_18097490 1.41 ENSDART00000144894
bcl11ba
B-cell CLL/lymphoma 11Ba (zinc finger protein)
chr6_-_15514726 1.40 ENSDART00000135583
mlpha
melanophilin a
chr14_-_25301744 1.40 ENSDART00000131886
slc25a48
solute carrier family 25, member 48
chr9_-_3700395 1.40 ENSDART00000102900
sp5a
Sp5 transcription factor a
chr15_+_9351511 1.39 ENSDART00000144381
sgcg
sarcoglycan, gamma
chr24_-_40968409 1.39 ENSDART00000169315
ENSDART00000171543
smyhc1
slow myosin heavy chain 1
chr3_-_27517052 1.39 ENSDART00000151625
si:ch211-157c3.4
si:ch211-157c3.4
chr5_+_36180981 1.37 ENSDART00000087191
mark4a
MAP/microtubule affinity-regulating kinase 4a
chr22_+_15480482 1.37 ENSDART00000125450
gpc1a
glypican 1a
chr9_-_31714290 1.35 ENSDART00000127214
tmtc4
transmembrane and tetratricopeptide repeat containing 4
chr3_+_15122138 1.35 ENSDART00000141752
asphd1
aspartate beta-hydroxylase domain containing 1
chr1_-_11163282 1.35 ENSDART00000033361
ttyh3b
tweety family member 3b
chr1_+_25662910 1.35 ENSDART00000113020
tet2
tet methylcytosine dioxygenase 2
chr23_+_24557956 1.34

chr12_-_48758684 1.32 ENSDART00000130190
uros
uroporphyrinogen III synthase
chr3_+_49277125 1.32 ENSDART00000161724
gas7a
growth arrest-specific 7a
chr3_+_23600462 1.30 ENSDART00000131410
hoxb3a
homeobox B3a
chr17_+_48999061 1.30 ENSDART00000177390
tiam2a
T-cell lymphoma invasion and metastasis 2a
chr16_-_21891429 1.29 ENSDART00000123597
ENSDARG00000089032
ENSDARG00000089032
chr23_+_19743720 1.28 ENSDART00000031872
kctd6b
potassium channel tetramerization domain containing 6b
chr6_-_12953515 1.27 ENSDART00000150036
ENSDART00000149940
adam23a
ADAM metallopeptidase domain 23a
chr17_+_45961986 1.26

chr5_+_51202141 1.26 ENSDART00000087467
cmya5
cardiomyopathy associated 5
chr19_-_19029640 1.25 ENSDART00000169489
p3h4
prolyl 3-hydroxylase family member 4 (non-enzymatic)
chr13_+_30546398 1.23

chr25_+_30535271 1.22

chr17_-_27247075 1.22

chr16_-_43441084 1.22 ENSDART00000058680
psma2
proteasome subunit alpha 2
chr8_+_7297981 1.21 ENSDART00000170975
BX469901.2
ENSDARG00000103232
chr15_+_15467483 1.19 ENSDART00000049831
dhrs11b
dehydrogenase/reductase (SDR family) member 11b
chr19_-_9603597 1.19 ENSDART00000045245
ing4
inhibitor of growth family, member 4
chr17_-_31041977 1.19 ENSDART00000104307
eml1
echinoderm microtubule associated protein like 1
chr23_-_7283514 1.18 ENSDART00000156369
CR589876.1
ENSDARG00000096997
chr19_-_22984081 1.18 ENSDART00000160153
pleca
plectin a
chr22_+_38276148 1.18 ENSDART00000104504
si:ch211-284e20.8
si:ch211-284e20.8
chr14_-_2245277 1.17 ENSDART00000169653
ENSDART00000160123
pcdh2ac
protocadherin 2 alpha c
chr16_+_5625552 1.17

chr1_-_54319943 1.17 ENSDART00000152666
slc25a23a
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23a
chr8_+_24725855 1.16 ENSDART00000078656
slc16a4
solute carrier family 16, member 4
chr18_-_26483645 1.15

chr9_+_33334773 1.15 ENSDART00000005879
atp5o
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr12_-_7902815 1.15 ENSDART00000088100
ank3b
ankyrin 3b
chr12_+_35912088 1.15 ENSDART00000167873
baiap2b
BAI1-associated protein 2b
chr7_-_35438887 1.14 ENSDART00000043857
irx5a
iroquois homeobox 5a
chr16_+_53111969 1.14 ENSDART00000011506
nkd2b
naked cuticle homolog 2b
chr25_-_325847 1.14 ENSDART00000059514
prickle1a
prickle homolog 1a
chr18_-_7423027 1.14 ENSDART00000147102
BX470218.1
ENSDARG00000094555
chr15_+_18710214 1.14 ENSDART00000166555
cadm1b
cell adhesion molecule 1b
chr6_-_39278328 1.13 ENSDART00000148531
arhgef25b
Rho guanine nucleotide exchange factor (GEF) 25b
chr23_+_35996491 1.13 ENSDART00000127384
hoxc9a
homeobox C9a
chr23_-_38228305 1.13 ENSDART00000131791
pfdn4
prefoldin subunit 4
chr16_+_21891184 1.13

chr5_+_18827478 1.12 ENSDART00000089078
acacb
acetyl-CoA carboxylase beta
chr6_-_40660116 1.12 ENSDART00000154359
ppil1
peptidylprolyl isomerase (cyclophilin)-like 1
chr3_+_23573114 1.12 ENSDART00000024256
hoxb6a
homeobox B6a
chr9_+_34510213 1.10 ENSDART00000035522
ENSDART00000170615
ENSDART00000146480
pou2f1b
POU class 2 homeobox 1b
chr13_+_1484997 1.09

chr3_+_36183975 1.09 ENSDART00000151305
slc16a6b
solute carrier family 16, member 6b
chr5_+_51201924 1.09 ENSDART00000087467
cmya5
cardiomyopathy associated 5
chr10_-_22967786 1.08

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.2 GO:0071549 propionate metabolic process(GO:0019541) propionate catabolic process(GO:0019543) glycerol biosynthetic process from pyruvate(GO:0046327) cellular response to dexamethasone stimulus(GO:0071549)
1.2 5.8 GO:0019857 5-methylcytosine catabolic process(GO:0006211) 5-methylcytosine metabolic process(GO:0019857)
0.8 2.5 GO:0048939 Golgi vesicle docking(GO:0048211) anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.8 3.3 GO:1901492 regulation of lymphangiogenesis(GO:1901490) positive regulation of lymphangiogenesis(GO:1901492)
0.6 3.7 GO:0051963 regulation of synapse assembly(GO:0051963) positive regulation of synapse assembly(GO:0051965)
0.6 1.7 GO:0014005 regulation of cellular amino acid metabolic process(GO:0006521) microglia development(GO:0014005) regulation of cellular amine metabolic process(GO:0033238)
0.5 3.8 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.5 2.7 GO:0010561 negative regulation of glycoprotein biosynthetic process(GO:0010561) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) negative regulation of glycoprotein metabolic process(GO:1903019)
0.5 4.2 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.5 1.6 GO:0061549 sympathetic ganglion development(GO:0061549)
0.5 1.5 GO:1990359 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.5 2.0 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.5 3.2 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.5 1.8 GO:1990090 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.4 3.5 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.4 2.6 GO:0033986 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.4 1.2 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.4 1.6 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.4 1.6 GO:0060544 regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544)
0.4 1.6 GO:0048713 regulation of oligodendrocyte differentiation(GO:0048713)
0.4 2.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.4 7.1 GO:0030199 collagen fibril organization(GO:0030199)
0.4 1.1 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.3 1.0 GO:1990092 calcium-dependent self proteolysis(GO:1990092)
0.3 1.0 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.3 7.7 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.3 4.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.3 3.7 GO:0021794 thalamus development(GO:0021794)
0.3 1.8 GO:0016082 synaptic vesicle priming(GO:0016082)
0.2 5.7 GO:0009612 response to mechanical stimulus(GO:0009612)
0.2 2.0 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 0.9 GO:0021730 trigeminal sensory nucleus development(GO:0021730)
0.2 0.9 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.2 0.7 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.2 1.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.2 2.2 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.2 2.1 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.2 2.1 GO:0046548 retinal rod cell development(GO:0046548)
0.2 1.7 GO:2000251 regulation of actin cytoskeleton reorganization(GO:2000249) positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.2 1.4 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.2 0.8 GO:0046888 negative regulation of hormone secretion(GO:0046888)
0.2 2.0 GO:0021592 fourth ventricle development(GO:0021592)
0.2 1.2 GO:0014721 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721) slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.2 1.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.2 1.1 GO:0044034 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.2 1.0 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.2 0.5 GO:0044806 multicellular organism aging(GO:0010259) G-quadruplex DNA unwinding(GO:0044806)
0.2 5.6 GO:0007416 synapse assembly(GO:0007416)
0.2 1.9 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.2 1.8 GO:0090311 regulation of protein deacetylation(GO:0090311)
0.2 4.3 GO:0006937 regulation of muscle contraction(GO:0006937)
0.2 0.8 GO:0035627 ceramide transport(GO:0035627)
0.1 7.8 GO:0050919 negative chemotaxis(GO:0050919)
0.1 2.5 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 0.4 GO:0061009 common bile duct development(GO:0061009)
0.1 0.9 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.1 0.4 GO:0034720 negative regulation of ossification(GO:0030279) histone H3-K4 demethylation(GO:0034720) histone H3-K36 demethylation(GO:0070544)
0.1 1.1 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 0.7 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) mitotic G1 DNA damage checkpoint(GO:0031571) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.1 0.9 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.1 2.5 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 0.3 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.3 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 0.6 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.9 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.1 0.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.5 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.1 2.4 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.1 0.8 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.4 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 2.0 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.1 1.3 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.7 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.1 0.3 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 0.7 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 9.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.4 GO:0051181 cofactor transport(GO:0051181)
0.1 1.1 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 0.8 GO:0070527 platelet aggregation(GO:0070527)
0.1 2.0 GO:0021986 habenula development(GO:0021986)
0.1 4.2 GO:0048596 embryonic camera-type eye morphogenesis(GO:0048596)
0.1 2.5 GO:0030318 melanocyte differentiation(GO:0030318)
0.1 2.8 GO:0010721 negative regulation of cell development(GO:0010721)
0.1 0.6 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 0.4 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 0.5 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.1 0.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 0.4 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.1 0.4 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 2.1 GO:0050770 regulation of axonogenesis(GO:0050770)
0.1 0.4 GO:1900045 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.1 2.0 GO:0042742 defense response to bacterium(GO:0042742)
0.1 3.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 0.9 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 1.2 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.1 0.4 GO:0021508 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.1 1.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.8 GO:0021955 central nervous system neuron axonogenesis(GO:0021955)
0.0 2.2 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 3.5 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 1.8 GO:0070509 calcium ion import(GO:0070509)
0.0 0.7 GO:0006826 iron ion transport(GO:0006826)
0.0 1.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.4 GO:0051905 establishment of pigment granule localization(GO:0051905)
0.0 5.0 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.3 GO:0031345 negative regulation of cell projection organization(GO:0031345)
0.0 1.3 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.5 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 0.3 GO:0007613 memory(GO:0007613)
0.0 0.2 GO:0042551 neuron maturation(GO:0042551)
0.0 1.5 GO:0030901 midbrain development(GO:0030901)
0.0 1.0 GO:0045766 positive regulation of angiogenesis(GO:0045766) positive regulation of vasculature development(GO:1904018)
0.0 2.2 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.2 GO:0098773 trabecula formation(GO:0060343) heart trabecula formation(GO:0060347) skin epidermis development(GO:0098773)
0.0 1.3 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.4 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.3 GO:0031274 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 1.2 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 2.5 GO:0002521 leukocyte differentiation(GO:0002521)
0.0 1.3 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.6 GO:0042073 intraciliary transport(GO:0042073) determination of ventral identity(GO:0048264)
0.0 1.6 GO:0006874 cellular calcium ion homeostasis(GO:0006874)
0.0 0.3 GO:0006825 copper ion transport(GO:0006825)
0.0 1.3 GO:0006821 chloride transport(GO:0006821)
0.0 0.1 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.3 GO:0043049 otic placode formation(GO:0043049)
0.0 0.6 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.5 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.4 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.5 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.0 0.7 GO:0016358 dendrite development(GO:0016358)
0.0 0.2 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.1 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457) chaperone-mediated protein complex assembly(GO:0051131)
0.0 1.5 GO:0006457 protein folding(GO:0006457)
0.0 1.4 GO:0060047 heart contraction(GO:0060047)
0.0 1.1 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.6 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 0.1 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.0 0.8 GO:0030041 actin filament polymerization(GO:0030041)
0.0 0.4 GO:0048332 mesoderm morphogenesis(GO:0048332)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.5 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.4 4.7 GO:0030056 hemidesmosome(GO:0030056)
0.3 7.7 GO:0016342 catenin complex(GO:0016342)
0.3 6.8 GO:0042734 presynaptic membrane(GO:0042734)
0.3 1.6 GO:1990246 uniplex complex(GO:1990246)
0.2 1.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 2.0 GO:0046930 pore complex(GO:0046930)
0.2 11.3 GO:0005581 collagen trimer(GO:0005581)
0.2 2.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 4.3 GO:0005861 troponin complex(GO:0005861)
0.2 2.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.2 1.9 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 2.1 GO:0036038 MKS complex(GO:0036038)
0.1 1.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 2.6 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 1.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.9 GO:0043679 axon terminus(GO:0043679)
0.1 1.9 GO:0048786 presynaptic active zone(GO:0048786)
0.1 4.3 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.1 GO:0016272 prefoldin complex(GO:0016272)
0.1 2.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 2.2 GO:0043204 perikaryon(GO:0043204)
0.1 1.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.8 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 4.2 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 5.6 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.8 GO:0045180 basal cortex(GO:0045180)
0.1 0.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.7 GO:0005776 autophagosome(GO:0005776)
0.0 6.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 17.8 GO:0005615 extracellular space(GO:0005615)
0.0 0.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 1.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.6 GO:0005686 U2 snRNP(GO:0005686)
0.0 1.3 GO:0030425 dendrite(GO:0030425)
0.0 0.8 GO:0008305 integrin complex(GO:0008305)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 1.8 GO:0030424 axon(GO:0030424)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 6.7 GO:0045202 synapse(GO:0045202)
0.0 0.9 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 1.3 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.0 0.7 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.0 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 0.7 GO:0030027 lamellipodium(GO:0030027)
0.0 0.4 GO:0005643 nuclear pore(GO:0005643)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.2 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
1.2 5.8 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.8 2.5 GO:0015168 polyol transmembrane transporter activity(GO:0015166) glycerol transmembrane transporter activity(GO:0015168)
0.8 2.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.6 1.9 GO:1903136 cuprous ion binding(GO:1903136)
0.6 6.8 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.6 3.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.6 2.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.5 4.3 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.5 1.5 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.5 1.8 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.4 3.5 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.4 4.7 GO:0030506 ankyrin binding(GO:0030506)
0.4 0.8 GO:0051185 coenzyme transporter activity(GO:0051185)
0.4 2.0 GO:0070492 oligosaccharide binding(GO:0070492)
0.4 21.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.4 1.8 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.3 1.5 GO:0034632 retinol transporter activity(GO:0034632)
0.3 2.4 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.3 1.5 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.3 2.4 GO:0048495 Roundabout binding(GO:0048495)
0.3 1.9 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.3 1.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.3 2.6 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.2 2.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 3.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 0.9 GO:0099528 G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.2 0.9 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.2 0.6 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.2 2.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 2.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 0.8 GO:0046624 ceramide transporter activity(GO:0035620) sphingolipid transporter activity(GO:0046624) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.2 2.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 1.8 GO:0015026 coreceptor activity(GO:0015026)
0.2 1.4 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.2 0.7 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.2 1.7 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 2.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.1 1.0 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 1.6 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 3.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 2.3 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 5.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 5.5 GO:0045296 cadherin binding(GO:0045296)
0.1 0.8 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.1 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.1 2.2 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 1.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.4 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 1.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.5 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.8 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.4 GO:0017022 myosin binding(GO:0017022)
0.1 1.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.8 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 1.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 2.5 GO:0005179 hormone activity(GO:0005179)
0.1 1.2 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.1 0.8 GO:0005518 collagen binding(GO:0005518)
0.0 0.8 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
0.0 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.8 GO:0015248 sterol transporter activity(GO:0015248)
0.0 1.3 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 1.2 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.2 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.9 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.7 GO:0050661 NADP binding(GO:0050661)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.3 GO:0016531 copper chaperone activity(GO:0016531)
0.0 1.3 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 1.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0019894 kinesin binding(GO:0019894)
0.0 1.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 2.6 GO:0060090 binding, bridging(GO:0060090)
0.0 10.6 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.3 GO:0051213 dioxygenase activity(GO:0051213)
0.0 0.3 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 17.4 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 2.6 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 1.7 GO:0000287 magnesium ion binding(GO:0000287)
0.0 4.9 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.5 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.3 PID ALK1 PATHWAY ALK1 signaling events
0.1 1.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 1.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 2.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 1.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 4.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 1.8 PID ATR PATHWAY ATR signaling pathway
0.0 2.1 PID E2F PATHWAY E2F transcription factor network
0.0 1.1 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 5.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.2 1.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 1.8 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 2.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 4.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 1.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 0.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.6 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 0.7 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.5 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 1.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.0 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 2.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.8 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.2 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.7 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation