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Results for nr2f1a

Z-value: 0.85

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Transcription factors associated with nr2f1a

Gene Symbol Gene ID Gene Info
ENSDARG00000052695 nuclear receptor subfamily 2, group F, member 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr2f1adr10_dc_chr5_+_49093134_490932260.861.6e-05Click!

Activity profile of nr2f1a motif

Sorted Z-values of nr2f1a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of nr2f1a

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_25157675 2.83 ENSDART00000136984
fatty acid binding protein 2, intestinal
chr16_-_45943282 2.48 ENSDART00000133213
antifreeze protein type IV
chr8_+_933677 2.35 ENSDART00000149528
fatty acid binding protein 1b, tandem duplicate 1
chr20_+_31366832 2.21 ENSDART00000133353
apolipoprotein Bb, tandem duplicate 1
chr22_-_17570306 2.11 ENSDART00000139361
glutathione peroxidase 4a
chr5_+_40722565 2.11 ENSDART00000097546
AT rich interactive domain 3C (BRIGHT-like)
chr12_-_5085227 1.99 ENSDART00000160729
retinol binding protein 4, plasma
chr16_-_45950530 1.95 ENSDART00000060822
antifreeze protein type IV
chr17_+_30687093 1.86 ENSDART00000179434
apolipoprotein Ba
chr12_+_27032862 1.84

chr22_+_15995914 1.69 ENSDART00000062618
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr3_+_39425125 1.67 ENSDART00000146867
aldolase a, fructose-bisphosphate, a
chr5_+_8415025 1.67 ENSDART00000046440
1-acylglycerol-3-phosphate O-acyltransferase 9, like
chr25_+_4490129 1.62

chr15_-_16948863 1.58 ENSDART00000062135
ENSDARG00000042379
chr9_-_39195468 1.55 ENSDART00000014207
myosin, light chain 1, alkali; skeletal, fast
chr2_-_42384993 1.50 ENSDART00000141358
apolipoprotein M
chr12_+_13080209 1.50 ENSDART00000127870
calymmin
chr3_-_45779817 1.50 ENSDART00000164361
glucagon receptor a
chr5_-_36237656 1.49 ENSDART00000032481
creatine kinase, muscle a
chr13_-_39033893 1.45 ENSDART00000045434
collagen, type IX, alpha 1b
chr22_+_37934447 1.40 ENSDART00000076082
fetuin B
chr16_+_23999029 1.38 ENSDART00000129525
apolipoprotein A-IV b, tandem duplicate 1
chr2_-_47578695 1.36 ENSDART00000014350
ENSDART00000038828
paired box 3a
chr18_+_31038010 1.35 ENSDART00000163471
urate (5-hydroxyiso-) hydrolase a
chr5_+_49093250 1.34 ENSDART00000133384
nuclear receptor subfamily 2, group F, member 1a
chr18_+_45893199 1.31 ENSDART00000158246
dishevelled segment polarity protein 3b
chr23_+_42488817 1.31 ENSDART00000171459
y cytochrome P450, family 2, subfamily AA, polypeptide 2
chr13_-_37001997 1.29 ENSDART00000135510
spectrin repeat containing, nuclear envelope 2b
chr6_+_48138737 1.27

chr23_-_9924987 1.26 ENSDART00000005015
protein kinase C binding protein 1, like
chr16_-_39181608 1.25 ENSDART00000075517
growth differentiation factor 6a
chr17_+_12254292 1.25 ENSDART00000160722
ketohexokinase
chr20_-_36984259 1.24 ENSDART00000076313
taxilin beta a
chr5_+_49093134 1.22 ENSDART00000133384
nuclear receptor subfamily 2, group F, member 1a
chr6_-_39315024 1.21 ENSDART00000012644
keratin 4
chr17_-_30685367 1.21 ENSDART00000114358
zgc:194392
chr24_-_14567403 1.19 ENSDART00000131830
junctophilin 1a
chr9_-_34491458 1.19 ENSDART00000049805
immunoglobulin-like domain containing receptor 2
chr22_+_30234718 1.19 ENSDART00000172496
adducin 3 (gamma) a
chr21_-_20674965 1.18 ENSDART00000065649
ENSDARG00000044676
chr3_-_31672763 1.17 ENSDART00000028270
glial fibrillary acidic protein
chr9_+_42112576 1.16 ENSDART00000130434
ENSDART00000007058
collagen type XVIII alpha 1 chain a
chr11_+_6118409 1.15 ENSDART00000027666
nuclear receptor subfamily 2, group F, member 6b
chr13_+_22350043 1.14 ENSDART00000136863
LIM domain binding 3a
chr3_-_18426055 1.12 ENSDART00000122968
aquaporin 8b
KN149909v1_+_1319 1.11

chr16_+_21436660 1.11 ENSDART00000145886
oxysterol binding protein-like 3b
chr11_+_21749658 1.09 ENSDART00000161485
forkhead box P4
chr17_+_1058137 1.08

chr16_+_25491981 1.08 ENSDART00000086333
jumonji, AT rich interactive domain 2a
chr5_-_1325831 1.08

chr11_+_26371444 1.06 ENSDART00000042322
microtubule-associated protein 1 light chain 3 alpha
chr19_+_156649 1.03 ENSDART00000167717
leucine rich repeat containing 16A
chr22_+_24362712 1.03 ENSDART00000157861
prolyl 3-hydroxylase 2
chr23_-_15442032 1.03 ENSDART00000082060
ENSDARG00000078145
chr18_+_9413588 1.03 ENSDART00000061886
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr7_-_18894639 1.01 ENSDART00000142924
kin of IRRE like a
chr25_+_5162045 1.01 ENSDART00000169540
ENSDARG00000101164
chr9_+_9524547 1.00 ENSDART00000061525
ENSDART00000125174
nuclear receptor subfamily 1, group I, member 2
chr11_+_11217547 1.00 ENSDART00000087105
myomesin 2a
chr14_+_28136958 0.99

chr14_-_49115338 0.96 ENSDART00000056712
electron-transferring-flavoprotein dehydrogenase
chr19_-_325337 0.96 ENSDART00000147635
glycerol-3-phosphate dehydrogenase 1c
chr2_+_32036450 0.96 ENSDART00000140776
ENSDARG00000091946
chr15_+_23849554 0.94 ENSDART00000138375
intraflagellar transport 20 homolog (Chlamydomonas)
chr2_+_42342148 0.93 ENSDART00000144716
caveolae associated protein 4a
chr19_-_30816780 0.93 ENSDART00000103475
anterior gradient 2
chr23_+_42381296 0.92 ENSDART00000158684
ENSDART00000159985
ENSDART00000172144
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr11_+_30482530 0.91 ENSDART00000103270
solute carrier family 22 (organic anion transporter), member 7a
chr12_-_37921731 0.91

chr23_+_36010592 0.91 ENSDART00000137507
homeo box C3a
chr13_+_1377875 0.90

chr20_+_2255204 0.89 ENSDART00000137579
si:ch73-18b11.2
chr23_+_24141576 0.89

chr5_+_1223598 0.89 ENSDART00000159783
ENSDART00000026535
ENSDART00000168130
ENSDART00000147972
dynamin 1a
chr2_-_43110857 0.89 ENSDART00000098303
otoconin 90
chr11_-_2107054 0.87 ENSDART00000173031
homeobox C6b
chr6_-_22227089 0.86 ENSDART00000168554
rhomboid, veinlet-like 3 (Drosophila)
chr21_+_25199691 0.86 ENSDART00000168140
ENSDART00000112783
transmembrane protein 45B
chr25_-_34638406 0.85 ENSDART00000123853
histone 1, H4, like
chr20_+_23643050 0.85 ENSDART00000168690
palladin, cytoskeletal associated protein
chr9_+_9524688 0.84 ENSDART00000061525
ENSDART00000125174
nuclear receptor subfamily 1, group I, member 2
chr21_-_44013995 0.84 ENSDART00000028960
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2
chr17_+_8874210 0.84

chr12_-_3903961 0.82 ENSDART00000134292
ENSDARG00000021154
chr10_-_32580373 0.81 ENSDART00000066793
diacylglycerol O-acyltransferase 2
chr1_-_50831155 0.81 ENSDART00000152719
sprouty-related, EVH1 domain containing 2a
chr2_+_37833161 0.81 ENSDART00000166352
short chain dehydrogenase/reductase family 39U, member 1
chr4_-_21931540 0.80 ENSDART00000174400
ribosomal protein S16
chr14_+_35906366 0.80 ENSDART00000105602
ELOVL fatty acid elongase 6
chr4_-_20435099 0.79 ENSDART00000055317
leucine rich repeat containing 17
chr12_-_31342432 0.79 ENSDART00000148603
acyl-CoA synthetase long-chain family member 5
chr23_+_44817648 0.79 ENSDART00000143688
discs, large homolog 4b (Drosophila)
chr14_-_48951428 0.78 ENSDART00000157785
Rap guanine nucleotide exchange factor (GEF) 2
chr9_-_1969197 0.77 ENSDART00000080608
homeobox D10a
chr15_+_28269289 0.77 ENSDART00000077736
vitronectin a
chr16_-_32059848 0.77 ENSDART00000138701
glutathione S-transferase kappa 1
chr16_-_24753560 0.76 ENSDART00000063083
paraoxonase 3, tandem duplicate 2
chr23_+_27985224 0.76 ENSDART00000171859
ENSDARG00000100606
chr20_-_53162473 0.75 ENSDART00000164460
GATA binding protein 4
chr7_-_38288929 0.75

KN150207v1_-_1208 0.75 ENSDART00000171112
ENSDARG00000099354
chr24_+_16249188 0.75 ENSDART00000164516
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr8_+_7655655 0.74 ENSDART00000170184
FYVE, RhoGEF and PH domain containing 1
chr14_-_16023198 0.74

chr1_-_25600988 0.74 ENSDART00000160381
CXXC finger 4
chr25_-_23949331 0.73 ENSDART00000047569
insulin-like growth factor 2b
chr23_+_42431407 0.73 ENSDART00000169821
cytochrome P450, family 2, subfamily AA, polypeptide 8
chr13_-_37144297 0.73

chr13_-_31413855 0.73 ENSDART00000005670
dehydrogenase/reductase (SDR family) member 7
chr23_-_35657313 0.72 ENSDART00000043429
junctophilin 2
chr5_+_26804344 0.72 ENSDART00000121886
ENSDART00000005025
hematopoietic death receptor
chr19_+_4996328 0.71 ENSDART00000165082
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr22_-_17652938 0.71 ENSDART00000139911
tight junction protein 3
chr13_-_219661 0.71 ENSDART00000133731
si:ch1073-291c23.2
chr2_-_59019569 0.71

chr20_+_40247918 0.71 ENSDART00000121818
triadin
chr23_-_26798851 0.70 ENSDART00000170576
ENSDART00000166123
heparan sulfate proteoglycan 2
chr9_+_16437408 0.70 ENSDART00000006787
eph receptor A3
chr12_-_34726359 0.70 ENSDART00000153026
NADH:ubiquinone oxidoreductase complex assembly factor 8
chr8_-_14146621 0.70 ENSDART00000063817
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11
chr10_-_44180588 0.70 ENSDART00000145404
crystallin, beta B1
chr6_-_39767452 0.69 ENSDART00000085277
phosphofructokinase, muscle b
chr7_+_31567166 0.69 ENSDART00000099785
ENSDART00000122506
myosin binding protein C, cardiac
chr2_+_30932612 0.69 ENSDART00000132450
ENSDART00000137012
myomesin 1a (skelemin)
chr21_+_5483017 0.69 ENSDART00000160885
starch binding domain 1
chr25_-_31881585 0.68 ENSDART00000123999
ENSDART00000158091
ENSDARG00000100731
KN150074v1_-_1031 0.68

chr17_+_6119323 0.67 ENSDART00000131075
dual specificity phosphatase 23b
chr3_-_22082170 0.67 ENSDART00000155490
microtubule-associated protein tau b
chr22_-_20101177 0.67 ENSDART00000138688
cAMP responsive element binding protein 3-like 3a
chr3_+_17913109 0.67 ENSDART00000112384
ankyrin repeat domain 40
chr19_-_5416317 0.66 ENSDART00000010373
keratin, type 1, gene 19d
chr18_-_23889256 0.65 ENSDART00000059976
nuclear receptor subfamily 2, group F, member 2
chr23_+_9285446 0.65 ENSDART00000033663
ribosomal protein S21
chr16_+_26900732 0.65 ENSDART00000042895
cadherin 17, LI cadherin (liver-intestine)
chr9_-_21257082 0.64 ENSDART00000124533
T-box 15
chr16_+_30068125 0.64 ENSDART00000147083
ENSDARG00000093232
chr10_-_44441481 0.63 ENSDART00000160231
strawberry notch homolog 1 (Drosophila)
chr23_-_20494890 0.63

chr5_-_29891016 0.63 ENSDART00000138464
pleckstrin homology-like domain, family B, member 1a
chr9_+_21340251 0.63 ENSDART00000133903
hydroxyacid oxidase 2 (long chain)
chr18_+_27753985 0.63 ENSDART00000141835
tetraspanin 18b
chr18_+_7350133 0.63 ENSDART00000172404
ceramide synthase 3b
chr11_+_30048913 0.63

chr7_+_50491026 0.63 ENSDART00000165037
si:ch73-380l10.2
chr8_+_25714744 0.62 ENSDART00000156340
si:ch211-167b20.8
chr11_+_37345024 0.62 ENSDART00000077496
heterochromatin protein 1, binding protein 3
chr8_+_48488009 0.62

chr3_-_24989269 0.62 ENSDART00000154724
chondroadherin-like a
chr20_+_18841440 0.62 ENSDART00000174532
family with sequence similarity 167, member Ab
chr12_+_23742199 0.62

chr14_+_33073643 0.61 ENSDART00000052780
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
KN150680v1_+_10854 0.61

chr7_-_52574822 0.61 ENSDART00000172951
microtubule-associated protein 1Aa
chr2_+_38057483 0.61 ENSDART00000159951
calsequestrin 1a
chr4_-_1346961 0.61 ENSDART00000164623
pleiotrophin
chr23_-_24468191 0.61 ENSDART00000044918
eph receptor A2 b
chr2_+_29862841 0.61 ENSDART00000135918
si:ch211-207d6.2
chr15_-_25582891 0.61

chr1_-_46015367 0.60 ENSDART00000074519
karyopherin alpha 3 (importin alpha 4)
chr4_-_16461748 0.60 ENSDART00000128835
wu:fc23c09
chr21_+_28441951 0.60 ENSDART00000077887
solute carrier family 22 (organic anion transporter), member 6, like
chr14_-_33596430 0.59 ENSDART00000112438
si:ch73-335m24.5
chr3_-_6325652 0.59 ENSDART00000168508
ENSDARG00000104099
chr20_+_25567046 0.59 ENSDART00000153071
phosphoribosylformylglycinamidine synthase
chr10_+_10393377 0.59 ENSDART00000109432
cerebral endothelial cell adhesion molecule
chr11_+_24720057 0.58 ENSDART00000145647
sulfatase 2a
chr15_-_37973812 0.58 ENSDART00000122439
si:dkey-238d18.4
chr23_+_42370612 0.57 ENSDART00000161812
cytochrome P450, family 2, subfamily AA, polypeptide 9
chr25_-_14948922 0.57 ENSDART00000161165
paired box 6a
chr9_+_32490721 0.57 ENSDART00000078608
heat shock 10 protein 1
chr11_+_6118322 0.57 ENSDART00000165031
nuclear receptor subfamily 2, group F, member 6b
chr23_-_34970838 0.57 ENSDART00000087219
ENSDARG00000061272
chr25_-_22890657 0.57

chr5_-_8568715 0.57 ENSDART00000099891
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit Eb
KN149795v1_-_24393 0.57

chr11_-_30117563 0.57 ENSDART00000078387
peroxisomal trans-2-enoyl-CoA reductase
chr17_-_1111115 0.56

chr20_+_230394 0.56 ENSDART00000002661
laminin, alpha 4
chr20_-_3970778 0.56 ENSDART00000178724
ENSDART00000178565
tripartite motif containing 67
chr5_+_61335845 0.56 ENSDART00000166482
ENSDART00000050884
ENSDART00000163909
selenoprotein W, 1
chr20_+_4120302 0.56 ENSDART00000159837
cnksr family member 3
chr4_-_25847471 0.56 ENSDART00000142491
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr11_-_8158013 0.55 ENSDART00000024046
urate oxidase
chr22_-_26971466 0.55 ENSDART00000087202
ENSDARG00000061256
chr23_-_624534 0.55 ENSDART00000132175
neural adhesion molecule L1.1
chr21_+_8106096 0.55 ENSDART00000011096
nuclear receptor subfamily 6, group A, member 1b
chr16_+_21121428 0.55

chr15_-_16271208 0.55

chr10_+_26786051 0.55 ENSDART00000100329
coagulation factor IXb
chr11_+_21749918 0.55 ENSDART00000161485
forkhead box P4
KN150642v1_+_9419 0.55 ENSDART00000159069
atonal bHLH transcription factor 1b
chr9_-_22140954 0.55 ENSDART00000146528
LIM domain 7a
chr23_+_32409339 0.55 ENSDART00000149698
solute carrier family 39 (zinc transporter), member 5
chr18_-_15963983 0.54 ENSDART00000127769
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr17_-_31041977 0.54 ENSDART00000104307
echinoderm microtubule associated protein like 1
chr8_-_23102555 0.54

chr5_+_62304435 0.53 ENSDART00000123243
translocase of inner mitochondrial membrane 22

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0042671 blood vessel maturation(GO:0001955) retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.3 1.7 GO:0060843 lymphatic endothelial cell fate commitment(GO:0060838) venous endothelial cell differentiation(GO:0060843) venous endothelial cell fate commitment(GO:0060845)
0.3 2.6 GO:0046865 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.3 0.9 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
0.3 3.6 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.3 3.9 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.3 0.5 GO:0048664 neuron fate determination(GO:0048664)
0.3 0.8 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.3 0.8 GO:0010747 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) regulation of organic acid transport(GO:0032890) positive regulation of organic acid transport(GO:0032892) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transport(GO:1903793) regulation of anion transmembrane transport(GO:1903959) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.3 0.8 GO:0072578 neurotransmitter-gated ion channel clustering(GO:0072578)
0.2 1.2 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.2 1.1 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.2 0.6 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.2 0.8 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.2 1.3 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.2 1.5 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.2 0.9 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.2 0.5 GO:0006833 water transport(GO:0006833)
0.2 0.7 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.2 0.5 GO:0086010 mechanosensory behavior(GO:0007638) membrane depolarization during action potential(GO:0086010)
0.2 0.9 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.2 1.7 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.2 1.7 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.2 1.4 GO:0050936 xanthophore differentiation(GO:0050936)
0.2 0.9 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 0.4 GO:0003242 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 4.4 GO:0060030 dorsal convergence(GO:0060030)
0.1 0.4 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 3.5 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.1 0.7 GO:0030104 water homeostasis(GO:0030104)
0.1 0.9 GO:1903963 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 0.4 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.1 0.3 GO:0097702 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246) response to oscillatory fluid shear stress(GO:0097702) cellular response to oscillatory fluid shear stress(GO:0097704)
0.1 0.3 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.1 0.4 GO:0031643 positive regulation of myelination(GO:0031643)
0.1 0.6 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 2.0 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.1 0.4 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.1 1.6 GO:0009743 response to carbohydrate(GO:0009743) response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.1 0.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.3 GO:0030800 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclic nucleotide metabolic process(GO:0030800) negative regulation of cyclic nucleotide biosynthetic process(GO:0030803) negative regulation of nucleotide biosynthetic process(GO:0030809) negative regulation of cAMP metabolic process(GO:0030815) negative regulation of cAMP biosynthetic process(GO:0030818) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350) negative regulation of purine nucleotide biosynthetic process(GO:1900372)
0.1 0.5 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.7 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.5 GO:0006567 glycine metabolic process(GO:0006544) threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.1 0.4 GO:0015882 L-ascorbic acid transport(GO:0015882)
0.1 0.3 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 0.6 GO:0061620 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.3 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 0.8 GO:0050919 negative chemotaxis(GO:0050919)
0.1 0.8 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.1 0.7 GO:0042102 positive regulation of mononuclear cell proliferation(GO:0032946) positive regulation of T cell proliferation(GO:0042102) positive regulation of lymphocyte proliferation(GO:0050671) positive regulation of leukocyte proliferation(GO:0070665)
0.1 0.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.3 GO:1901490 regulation of lymphangiogenesis(GO:1901490) positive regulation of lymphangiogenesis(GO:1901492)
0.1 1.5 GO:0044259 collagen metabolic process(GO:0032963) multicellular organismal macromolecule metabolic process(GO:0044259)
0.1 0.7 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.9 GO:0070831 basement membrane assembly(GO:0070831)
0.1 0.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 0.5 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.8 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 0.2 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 1.1 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 1.1 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.1 0.3 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 0.3 GO:0035776 pronephric proximal tubule development(GO:0035776)
0.1 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.4 GO:0070199 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.1 0.3 GO:0045144 meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177) meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.2 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.3 GO:0035313 negative regulation of Rac protein signal transduction(GO:0035021) wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.1 0.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.3 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.3 GO:0061036 positive regulation of chondrocyte differentiation(GO:0032332) positive regulation of cartilage development(GO:0061036)
0.0 0.4 GO:0006152 purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.8 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 0.2 GO:2001044 regulation of integrin-mediated signaling pathway(GO:2001044)
0.0 0.2 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.7 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.8 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.5 GO:0030656 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.3 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 1.8 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.2 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 0.8 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.2 GO:0060394 SMAD protein complex assembly(GO:0007183) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.9 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.6 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 0.2 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.7 GO:0046847 filopodium assembly(GO:0046847)
0.0 3.9 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.4 GO:0060974 cell migration involved in heart formation(GO:0060974)
0.0 0.9 GO:0010906 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.0 0.1 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.2 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.8 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.1 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.1 GO:0071632 optomotor response(GO:0071632)
0.0 0.4 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.8 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.4 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.6 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.6 GO:0071248 cellular response to metal ion(GO:0071248)
0.0 1.7 GO:0006979 response to oxidative stress(GO:0006979)
0.0 0.3 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.2 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.7 GO:0007416 synapse assembly(GO:0007416)
0.0 0.5 GO:0007599 blood coagulation(GO:0007596) hemostasis(GO:0007599)
0.0 0.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.9 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.9 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 1.0 GO:0001755 neural crest cell migration(GO:0001755)
0.0 0.2 GO:0009409 response to cold(GO:0009409)
0.0 0.8 GO:0035272 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.0 1.3 GO:0021782 glial cell development(GO:0021782)
0.0 0.3 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.4 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 1.3 GO:0033993 response to lipid(GO:0033993)
0.0 0.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.6 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 1.3 GO:0006936 muscle contraction(GO:0006936)
0.0 0.4 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.6 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.1 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 1.6 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.2 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.0 0.1 GO:0048899 anterior lateral line development(GO:0048899)
0.0 0.6 GO:0016358 dendrite development(GO:0016358)
0.0 0.8 GO:0007601 visual perception(GO:0007601)
0.0 0.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.6 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.4 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 1.6 GO:0006869 lipid transport(GO:0006869)
0.0 2.4 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.7 GO:0006865 amino acid transport(GO:0006865)
0.0 0.5 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.6 GO:0006633 fatty acid biosynthetic process(GO:0006633)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.1 GO:0042627 chylomicron(GO:0042627)
0.6 1.9 GO:0030314 junctional membrane complex(GO:0030314)
0.3 0.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 1.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 1.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 0.9 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.2 1.7 GO:0031430 M band(GO:0031430)
0.1 0.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.6 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 0.9 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 3.2 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.6 GO:0045095 keratin filament(GO:0045095)
0.1 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.6 GO:0042788 polysomal ribosome(GO:0042788)
0.1 3.0 GO:0005581 collagen trimer(GO:0005581)
0.1 1.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 1.3 GO:0044420 basement membrane(GO:0005604) extracellular matrix component(GO:0044420)
0.0 0.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.2 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0014704 intercalated disc(GO:0014704)
0.0 0.2 GO:0030990 intraciliary transport particle(GO:0030990)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.5 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 1.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.9 GO:0000421 autophagosome membrane(GO:0000421)
0.0 2.1 GO:0005882 intermediate filament(GO:0005882)
0.0 1.1 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.9 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.1 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 16.7 GO:0005576 extracellular region(GO:0005576)
0.0 0.3 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.9 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.0 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.4 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0030125 clathrin vesicle coat(GO:0030125)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.6 4.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.5 5.2 GO:0005504 fatty acid binding(GO:0005504)
0.5 2.3 GO:0034632 retinol transporter activity(GO:0034632)
0.4 1.5 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.3 1.3 GO:0033971 hydroxyisourate hydrolase activity(GO:0033971)
0.3 1.7 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.3 1.6 GO:0015250 water channel activity(GO:0015250)
0.2 1.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.2 1.3 GO:0048039 ubiquinone binding(GO:0048039)
0.2 0.8 GO:0004064 arylesterase activity(GO:0004064)
0.2 1.5 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.2 1.7 GO:0001972 retinoic acid binding(GO:0001972)
0.2 1.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.6 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 0.7 GO:2001070 starch binding(GO:2001070)
0.1 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.5 GO:0017046 peptide hormone binding(GO:0017046)
0.1 0.9 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 1.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.8 GO:0043495 protein anchor(GO:0043495)
0.1 0.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.4 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.1 2.3 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 3.5 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 0.8 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.3 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.1 0.7 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.6 GO:0003872 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.1 0.8 GO:0048495 Roundabout binding(GO:0048495)
0.1 1.2 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.3 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 0.3 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 0.9 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 0.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.8 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.6 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.1 0.9 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 1.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.4 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 0.3 GO:0099528 G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.1 0.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 4.0 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 0.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 0.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.7 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 1.1 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.6 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 1.1 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.4 GO:0015145 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.0 2.3 GO:0008201 heparin binding(GO:0008201)
0.0 0.3 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.1 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.2 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.0 0.8 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.6 GO:0010181 FMN binding(GO:0010181)
0.0 0.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.5 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.6 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 1.3 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0070300 phosphatidic acid binding(GO:0070300) phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0 0.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.6 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.8 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.3 GO:0030546 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.5 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.2 GO:0034595 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 1.3 GO:0005125 cytokine activity(GO:0005125)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.0 0.4 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 3.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.3 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0048038 quinone binding(GO:0048038)
0.0 0.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.5 GO:0005179 hormone activity(GO:0005179)
0.0 1.0 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.5 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.3 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 2.4 GO:0051015 actin filament binding(GO:0051015)
0.0 1.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.2 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 0.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 0.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.6 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.2 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.3 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 1.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.6 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 3.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.0 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 1.2 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.7 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 1.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production