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Results for nr2f1b+nr2f5

Z-value: 0.66

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Transcription factors associated with nr2f1b+nr2f5

Gene Symbol Gene ID Gene Info
nr2f1b
ENSDARG00000017168 nuclear receptor subfamily 2, group F, member 1b
nr2f5
ENSDARG00000033172 nuclear receptor subfamily 2, group F, member 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr2f5dr10_dc_chr16_+_46327528_463276380.923.9e-07Click!
nr2f1bdr10_dc_chr10_+_43950311_439503560.844.6e-05Click!

Activity profile of nr2f1b+nr2f5 motif

Sorted Z-values of nr2f1b+nr2f5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of nr2f1b+nr2f5

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_+_64175669 1.93 ENSDART00000050863
zgc:101858
zgc:101858
chr21_+_28408329 1.49 ENSDART00000077871
pygma
phosphorylase, glycogen, muscle A
chr15_+_27431469 1.39 ENSDART00000122101
tbx2b
T-box 2b
chr15_-_27431216 1.25 ENSDART00000155933
AL954322.2
ENSDARG00000097072
chr20_-_11179880 1.25 ENSDART00000152246
flrt2
fibronectin leucine rich transmembrane protein 2
chr22_-_26971466 1.18 ENSDART00000087202
ENSDARG00000061256
ENSDARG00000061256
chr13_-_22877318 1.10 ENSDART00000057638
ENSDART00000171778
hk1
hexokinase 1
chr15_+_1238615 1.06 ENSDART00000167760
ENSDART00000163827
mfsd1
major facilitator superfamily domain containing 1
chr17_+_17935213 1.04 ENSDART00000104999
ccdc85ca
coiled-coil domain containing 85C, a
chr14_-_24094142 0.99 ENSDART00000126894
fam13b
family with sequence similarity 13, member B
KN149883v1_-_5164 0.98 ENSDART00000158506
ENSDART00000172360
NDUFA13
NADH:ubiquinone oxidoreductase subunit A13
KN150642v1_+_9419 0.97 ENSDART00000159069
atoh1b
atonal bHLH transcription factor 1b
chr20_-_17006936 0.97 ENSDART00000012859
psma6b
proteasome subunit alpha 6b
chr6_-_39053400 0.96 ENSDART00000165839
tns2b
tensin 2b
chr2_+_33399405 0.96 ENSDART00000137207
slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr2_+_53253623 0.96 ENSDART00000121980
creb3l3b
cAMP responsive element binding protein 3-like 3b
chr10_-_21096635 0.93 ENSDART00000091004
pcdh1a
protocadherin 1a
chr1_-_55162455 0.92 ENSDART00000137909
samd1b
sterile alpha motif domain containing 1b
chr19_+_12315183 0.86 ENSDART00000149221
grhl2b
grainyhead-like transcription factor 2b
chr1_-_55108003 0.84 ENSDART00000142069
ENSDART00000043933
ndufb7
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7
chr12_-_3742020 0.75 ENSDART00000092983
ENSDARG00000063555
ENSDARG00000063555
chr1_-_47080507 0.71 ENSDART00000101079
neurl1aa
neuralized E3 ubiquitin protein ligase 1Aa
chr12_+_17744208 0.67

chr21_+_25651712 0.66 ENSDART00000135123
si:dkey-17e16.17
si:dkey-17e16.17
chr13_+_24703802 0.66 ENSDART00000101274
zgc:153981
zgc:153981
chr3_-_12818954 0.65 ENSDART00000158747
ENSDART00000158815
pdgfab
platelet-derived growth factor alpha polypeptide b
chr8_-_41266057 0.64 ENSDART00000108518
rnf10
ring finger protein 10
chr5_+_64175494 0.59 ENSDART00000050863
zgc:101858
zgc:101858
chr16_+_21090083 0.56 ENSDART00000052662
hoxa13b
homeobox A13b
chr23_-_3760604 0.53 ENSDART00000143731
pacsin1a
protein kinase C and casein kinase substrate in neurons 1a
chr23_+_24010310 0.44 ENSDART00000171029
ptpn11b
protein tyrosine phosphatase, non-receptor type 11, b
chr4_+_1680973 0.44 ENSDART00000149826
ENSDART00000166437
ENSDART00000031135
ENSDART00000172300
ENSDART00000067446
slc38a4
solute carrier family 38, member 4
chr11_+_43136945 0.44

chr7_+_26980284 0.43 ENSDART00000173962
sox6
SRY (sex determining region Y)-box 6
chr3_+_27615311 0.43

chr2_+_58654570 0.41 ENSDART00000164102
ENSDART00000158777
cirbpa
cold inducible RNA binding protein a
chr1_-_47080468 0.37 ENSDART00000101079
neurl1aa
neuralized E3 ubiquitin protein ligase 1Aa
chr4_-_70713033 0.35 ENSDART00000169130
ftr64
finTRIM family, member 64
chr7_+_30803603 0.34 ENSDART00000173805
tjp1a
tight junction protein 1a
chr11_-_25086785 0.34 ENSDART00000158598
si:ch211-232b12.5
si:ch211-232b12.5
chr2_+_21947475 0.29 ENSDART00000112014
mplkip
M-phase specific PLK1 interacting protein
chr22_+_18291117 0.28 ENSDART00000137985
gatad2ab
GATA zinc finger domain containing 2Ab
chr18_+_12452 0.27

chr16_+_48729441 0.27 ENSDART00000154683
CU694532.1
ENSDARG00000097878
chr14_-_5510157 0.26 ENSDART00000131820
kazald2
Kazal-type serine peptidase inhibitor domain 2
chr20_+_46969915 0.25 ENSDART00000158124
ENSDARG00000103380
ENSDARG00000103380
chr2_-_9809756 0.24 ENSDART00000056899
txndc12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr25_+_1511300 0.24 ENSDART00000093277
ppm1h
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr4_+_9010890 0.22 ENSDART00000058007
samm50l
sorting and assembly machinery component 50 homolog, like
chr6_+_9441851 0.21 ENSDART00000064995
sumo1
small ubiquitin-like modifier 1
chr5_-_24580478 0.18 ENSDART00000138209
dph7
diphthamide biosynthesis 7
chr2_+_3062119 0.17 ENSDART00000110416
eif2b5
eukaryotic translation initiation factor 2B, subunit 5 epsilon
chr23_+_36494295 0.17 ENSDART00000042701
pip4k2ca
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma a
chr10_-_21096686 0.16 ENSDART00000139733
pcdh1a
protocadherin 1a
chr20_-_11179958 0.14 ENSDART00000152246
flrt2
fibronectin leucine rich transmembrane protein 2
chr1_-_20131454 0.12

chr12_+_26972001 0.11

chr7_+_28881845 0.11 ENSDART00000138065
tmppe
transmembrane protein with metallophosphoesterase domain
chr18_-_11707 0.11 ENSDART00000159781
WHAMM
WAS protein homolog associated with actin, golgi membranes and microtubules
chr12_+_26971596 0.11

chr7_+_20829933 0.10 ENSDART00000173612
serpinh2
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr16_+_54024920 0.10 ENSDART00000155929
nod1
nucleotide-binding oligomerization domain containing 1
chr15_-_35075545 0.10 ENSDART00000006288
dhx16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr21_+_5775383 0.08 ENSDART00000165065
uqcr10
ubiquinol-cytochrome c reductase, complex III subunit X
chr1_-_39414732 0.08 ENSDART00000135647
si:ch211-113e8.10
si:ch211-113e8.10
chr20_+_53772078 0.08 ENSDART00000126983
myh6
myosin, heavy chain 6, cardiac muscle, alpha
chr15_+_2556736 0.04 ENSDART00000063329
cux1b
cut-like homeobox 1b
chr14_-_33468547 0.03

chr19_+_27243907 0.03 ENSDART00000126006
FP085398.1
ENSDARG00000087611
chr10_-_76359 0.00 ENSDART00000144722
dyrk1aa
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, a

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:0048664 neuron fate determination(GO:0048664)
0.2 1.0 GO:0099565 chemical synaptic transmission, postsynaptic(GO:0099565)
0.2 0.6 GO:0031643 positive regulation of myelination(GO:0031643)
0.1 1.5 GO:0009251 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 0.3 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 1.1 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.1 0.2 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.1 0.6 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.4 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.1 0.9 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.0 1.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.5 GO:1900006 membrane tubulation(GO:0097320) positive regulation of dendrite development(GO:1900006)
0.0 1.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0055004 atrial cardiac myofibril assembly(GO:0055004)
0.0 0.1 GO:0071684 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 1.0 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.2 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.4 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 0.4 GO:0003333 amino acid transmembrane transport(GO:0003333)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.8 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.4 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.1 GO:0014069 postsynaptic density(GO:0014069)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.2 1.1 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.0 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.6 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.1 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases