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Results for nr5a1a+nr5a2+nr5a5

Z-value: 0.92

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Transcription factors associated with nr5a1a+nr5a2+nr5a5

Gene Symbol Gene ID Gene Info
ENSDARG00000039116 nuclear receptor subfamily 5, group A, member 5
ENSDARG00000100940 nuclear receptor subfamily 5, group A, member 2
ENSDARG00000103176 nuclear receptor subfamily 5, group A, member 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr5a2dr10_dc_chr22_-_22694364_226944190.792.6e-04Click!

Activity profile of nr5a1a+nr5a2+nr5a5 motif

Sorted Z-values of nr5a1a+nr5a2+nr5a5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of nr5a1a+nr5a2+nr5a5

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_-_30816780 2.76 ENSDART00000103475
anterior gradient 2
chr2_+_42342148 1.95 ENSDART00000144716
caveolae associated protein 4a
chr7_-_25623974 1.94 ENSDART00000173602
CD99 molecule-like 2
chr9_-_1969197 1.94 ENSDART00000080608
homeobox D10a
chr23_+_25782195 1.81 ENSDART00000060059
RNA binding motif, single stranded interacting protein 2b
chr7_-_28425307 1.78 ENSDART00000148822
adhesion G protein-coupled receptor G1
chr3_+_1413640 1.77 ENSDART00000055430
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6
chr20_+_51388214 1.77 ENSDART00000153452
heat shock protein 90, alpha (cytosolic), class B member 1
chr14_-_31676235 1.73 ENSDART00000105761
zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)
chr13_-_13163676 1.73 ENSDART00000125883
ENSDART00000013534
fibroblast growth factor receptor 3
chr5_+_55598181 1.69 ENSDART00000021159
LIM homeobox 1b
chr22_+_33177432 1.69 ENSDART00000126885
dystroglycan 1
chr7_+_25642061 1.61 ENSDART00000135728
high mobility group box 3a
chr22_-_2870591 1.61 ENSDART00000063533
aquaporin 12
chr20_+_230394 1.54 ENSDART00000002661
laminin, alpha 4
chr19_-_12226198 1.54 ENSDART00000032474
ENSDART00000151056
ENSDART00000167360
poly A binding protein, cytoplasmic 1 b
chr6_-_15526547 1.49 ENSDART00000038133
tripartite motif containing 63a
chr20_+_51388313 1.46 ENSDART00000153452
heat shock protein 90, alpha (cytosolic), class B member 1
chr7_-_8635687 1.44 ENSDART00000081620
ventral anterior homeobox 2
chr19_+_5375413 1.44 ENSDART00000141237
si:dkeyp-113d7.10
chr25_-_4376129 1.43

chr4_-_21931540 1.42 ENSDART00000174400
ribosomal protein S16
chr7_+_25641990 1.41 ENSDART00000129924
high mobility group box 3a
chr23_+_17856053 1.36 ENSDART00000154427
ENSDARG00000097211
chr7_-_57941497 1.36 ENSDART00000114008
un-named hu7910
chr11_-_7310284 1.35 ENSDART00000091664
adenomatosis polyposis coli 2
chr13_-_22877318 1.33 ENSDART00000057638
ENSDART00000171778
hexokinase 1
chr3_+_27684309 1.33

chr5_+_26829686 1.32 ENSDART00000087894
zgc:153409
chr5_-_21523520 1.27 ENSDART00000023306
ankyrin repeat and SOCS box-containing 12a
chr3_-_26393945 1.25 ENSDART00000087118
xylosyltransferase I
chr2_-_20941256 1.25 ENSDART00000114199
si:ch211-267e7.3
chr7_+_34417030 1.24 ENSDART00000108473
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr14_+_34174018 1.24 ENSDART00000024440
forkhead box I3b
chr18_+_20504980 1.23 ENSDART00000060295
receptor-associated protein of the synapse, 43kD
chr2_-_28244864 1.20 ENSDART00000137542
zgc:163121
chr5_-_34701639 1.20 ENSDART00000085142
microtubule-associated protein 1B
chr12_-_48493654 1.20 ENSDART00000162603
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8
chr24_-_16884946 1.19 ENSDART00000171988
prostaglandin D2 synthase b, tandem duplicate 2
chr7_-_33080261 1.13 ENSDART00000114041
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr7_-_23933499 1.13 ENSDART00000087298
guanosine monophosphate reductase 2
chr19_+_14197118 1.12 ENSDART00000166230
trophoblast glycoprotein a
chr13_-_13163801 1.12 ENSDART00000156968
fibroblast growth factor receptor 3
chr2_+_30932612 1.11 ENSDART00000132450
ENSDART00000137012
myomesin 1a (skelemin)
chr15_-_26619404 1.10 ENSDART00000150152
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr7_+_20215723 1.10 ENSDART00000173724
ENSDART00000173773
si:dkey-33c9.8
chr7_-_25816549 1.09 ENSDART00000052989
ENSDART00000047951
acetylcholinesterase
chr12_-_457997 1.08 ENSDART00000143232
dehydrogenase/reductase (SDR family) member 7Cb
chr3_-_39287733 1.07

chr18_-_25010085 1.06 ENSDART00000133786
si:ch211-196l7.4
chr7_-_25816655 1.03 ENSDART00000052989
ENSDART00000047951
acetylcholinesterase
chr19_+_21140010 1.02 ENSDART00000090757
K(lysine) acetyltransferase 2B
chr15_+_37204488 1.01 ENSDART00000157762
amyloid beta (A4) precursor-like protein 1
chr16_-_21120115 1.01

chr23_+_25428372 0.99 ENSDART00000147440
formin-like 3
chr20_+_34417665 0.98 ENSDART00000153207
influenza virus NS1A binding protein a
chr3_-_21149752 0.98 ENSDART00000003939
synaptogyrin 1a
chr4_+_14361566 0.98 ENSDART00000007103
NUAK family, SNF1-like kinase, 1a
chr5_-_70939686 0.98

chr5_-_34701743 0.97 ENSDART00000085142
microtubule-associated protein 1B
chr16_+_32605735 0.97 ENSDART00000093250
POU class 3 homeobox 2b
chr2_-_58272475 0.97 ENSDART00000166282
ENSDART00000159040
purine nucleoside phosphorylase 5b
chr3_-_32727588 0.96 ENSDART00000158916
si:dkey-16l2.20
chr14_-_1081316 0.96

chr19_-_9793494 0.95 ENSDART00000134816
solute carrier family 2 (facilitated glucose transporter), member 3a
chr6_-_39346614 0.95 ENSDART00000104074
zgc:158846
chr16_+_55351732 0.95 ENSDART00000109391
ENSDARG00000077559
chr14_-_5371581 0.95 ENSDART00000012116
T-cell leukemia, homeobox 2
chr14_+_5852295 0.94 ENSDART00000128638
Bernardinelli-Seip congenital lipodystrophy 2, like
chr1_-_4757890 0.94 ENSDART00000114035
motor neuron and pancreas homeobox 2b
chr18_+_17594381 0.93 ENSDART00000010998
solute carrier family 12 (sodium/chloride transporter), member 3
chr3_-_40159349 0.93 ENSDART00000055186
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
chr18_-_15963983 0.92 ENSDART00000127769
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr8_+_10267246 0.92 ENSDART00000159312
ENSDART00000160766
Pim-1 proto-oncogene, serine/threonine kinase
chr14_-_11947241 0.91 ENSDART00000115101
myotilin
chr4_-_16356071 0.91 ENSDART00000079521
keratocan
chr9_+_30774173 0.90 ENSDART00000160590
TBC1 domain family, member 4
chr23_+_18796386 0.89 ENSDART00000137438
myosin, heavy chain 7B, cardiac muscle, beta b
chr19_+_47719438 0.88 ENSDART00000138295
exostoses (multiple) 1c
chr25_-_34599079 0.87 ENSDART00000156727
si:dkey-108k21.21
chr6_+_20276828 0.87 ENSDART00000128047
ubiquinol-cytochrome c reductase core protein I
chr25_-_21718782 0.87 ENSDART00000175132
ENSDARG00000051873
chr2_+_43736542 0.87 ENSDART00000148454
integrin, beta 1b.1
chr5_+_50947650 0.86 ENSDART00000058403
creatine kinase, mitochondrial 2b (sarcomeric)
chr8_-_11806627 0.86 ENSDART00000064017
Rap guanine nucleotide exchange factor (GEF) 1a
chr11_+_30416115 0.86 ENSDART00000161662
tau tubulin kinase 1a
chr15_-_1225595 0.86

chr16_+_53221957 0.84

chr22_-_10324166 0.84 ENSDART00000092050
stabilin 1
chr4_+_22754618 0.84

chr8_-_52729505 0.84 ENSDART00000168241
tubulin, beta 2b
chr7_-_58540731 0.83 ENSDART00000167231
mitochondrial ribosomal protein L15
chr20_-_28981879 0.81 ENSDART00000134564
ENSDART00000132127
serine/arginine-rich splicing factor 5b
chr20_+_230164 0.81 ENSDART00000002661
laminin, alpha 4
chr3_-_52419408 0.80 ENSDART00000154260
si:dkey-210j14.4
chr6_+_41557636 0.80 ENSDART00000084834
SLIT-ROBO Rho GTPase activating protein 3
chr2_+_37985514 0.80 ENSDART00000149224
apolipoprotein L, 1
chr19_-_27807312 0.80

chr12_-_3903961 0.80 ENSDART00000134292
ENSDARG00000021154
chr20_+_7337738 0.79 ENSDART00000165596
desmoglein 2, tandem duplicate 1
chr23_+_17856104 0.79 ENSDART00000154427
ENSDARG00000097211
chr8_-_23102555 0.78

chr10_+_29351676 0.78 ENSDART00000088973
synaptotagmin-like 2a
chr13_-_2083873 0.77 ENSDART00000129773
muscular LMNA-interacting protein
chr21_-_19789339 0.77

chr1_+_9999842 0.77 ENSDART00000152438
ENSDARG00000037679
chr7_-_57727148 0.77

chr9_-_28292714 0.76 ENSDART00000146284
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr5_-_24568752 0.76 ENSDART00000145061
patatin-like phospholipase domain containing 7b
chr24_+_26287471 0.75 ENSDART00000105784
ENSDART00000122554
claudin 11b
chr25_+_1747864 0.75

chr8_+_23192085 0.75 ENSDART00000032996
ENSDART00000137536
pancreatic progenitor cell differentiation and proliferation factor a
chr10_+_37983342 0.75 ENSDART00000172548
basic helix-loop-helix family, member a9
chr23_+_25930072 0.74 ENSDART00000124103
hepatocyte nuclear factor 4, alpha
chr17_+_7438152 0.72 ENSDART00000130625
si:dkeyp-110a12.4
chr4_-_72097569 0.72 ENSDART00000108669
zgc:171551
chr17_-_12231165 0.71 ENSDART00000080927
synaptosomal-associated protein, 25b
chr23_+_14058972 0.71 ENSDART00000090864
leiomodin 3 (fetal)
chr12_-_36415239 0.70

chr20_+_26408687 0.70

chr12_-_25110150 0.70 ENSDART00000077188
cytochrome c oxidase subunit VIIa polypeptide 3
chr18_+_41323776 0.70 ENSDART00000048985
ventricular zone expressed PH domain-containing 1
chr23_-_19053587 0.69

chr10_+_9259213 0.68 ENSDART00000064966
sorting nexin 18b
chr16_-_30698002 0.68 ENSDART00000146508
low density lipoprotein receptor class A domain containing 4b
chr17_-_26592356 0.68 ENSDART00000016608
mitochondrial ribosomal protein L57
chr12_+_7421078 0.67 ENSDART00000163114
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr19_-_9793444 0.67 ENSDART00000134816
solute carrier family 2 (facilitated glucose transporter), member 3a
chr21_-_20305406 0.67 ENSDART00000065659
retinol binding protein 4, like
chr11_-_18442094 0.67 ENSDART00000159380
zinc finger, MYND-type containing 8
chr15_-_4536026 0.67

chr23_+_35988395 0.66 ENSDART00000154825
homeo box C3a
chr7_-_71958596 0.66

chr14_-_24814149 0.66 ENSDART00000158108
si:rp71-1d10.8
chr7_-_8635989 0.65 ENSDART00000081620
ventral anterior homeobox 2
chr10_-_17383380 0.65

chr19_+_10912601 0.65 ENSDART00000053325
translocase of outer mitochondrial membrane 40 homolog, like
chr19_-_27878747 0.64 ENSDART00000137638
si:ch73-25f10.6
chr8_+_7237516 0.64

chr16_-_22903823 0.63

chr22_+_31866783 0.63 ENSDART00000159825
dedicator of cytokinesis 3
chr13_+_50062513 0.61 ENSDART00000124142
ENSDART00000099537
cytochrome c oxidase subunit Vb 2
chr13_-_18064929 0.61 ENSDART00000079902
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr7_-_27877036 0.61 ENSDART00000044208
LIM domain only 1
chr14_-_29487265 0.61

chr17_-_50899135 0.57

chr2_-_2509717 0.56 ENSDART00000082143
ENSDART00000158864
protein kinase, cAMP-dependent, catalytic, beta b
chr11_-_29908609 0.56 ENSDART00000156196
sex comb on midleg-like 2 (Drosophila)
chr12_-_34621359 0.56

KN149817v1_+_2207 0.55

chr22_+_12406830 0.55 ENSDART00000108609
Rho family GTPase 3a
chr13_+_41998500 0.54 ENSDART00000074707
CDC42 effector protein (Rho GTPase binding) 3
chr2_+_32796877 0.54 ENSDART00000082250
zgc:136930
chr23_-_22186674 0.53 ENSDART00000142474
polyhomeotic homolog 2a (Drosophila)
chr10_-_32580373 0.53 ENSDART00000066793
diacylglycerol O-acyltransferase 2
chr9_+_17341042 0.53 ENSDART00000147488
SLAIN motif family, member 1a
chr25_-_35094733 0.53 ENSDART00000153827
caseinolytic mitochondrial matrix peptidase chaperone subunit b
chr1_-_44239584 0.53 ENSDART00000137216
transmembrane protein 176
chr4_+_25637474 0.52 ENSDART00000066942
ENSDART00000041965
acyl-CoA thioesterase 15
chr3_+_19863136 0.52 ENSDART00000078974
transmembrane and ubiquitin-like domain containing 2
chr11_+_2786083 0.52 ENSDART00000172837
kinesin family member 21B
chr20_+_35183329 0.52 ENSDART00000114262
CDC42 binding protein kinase alpha (DMPK-like) b
chr14_-_35074225 0.51 ENSDART00000129460
ribonuclease H2, subunit C
chr18_-_47186938 0.51

chr3_-_39287813 0.50

chr13_-_29290894 0.50 ENSDART00000150228
choline O-acetyltransferase a
chr5_-_31845561 0.49 ENSDART00000157295
ENSDART00000159522
neuronal calcium sensor 1a
chr10_-_17383466 0.49

chr10_+_42546351 0.49 ENSDART00000020000
cytochrome c oxidase subunit 5B
chr20_-_53162473 0.48 ENSDART00000164460
GATA binding protein 4
chr17_-_31041977 0.48 ENSDART00000104307
echinoderm microtubule associated protein like 1
chr2_+_289138 0.48 ENSDART00000157246
zinc finger protein 1008
chr17_+_21433543 0.47 ENSDART00000079030
phospholipase A2, group IVF, tandem duplicate 1
chr9_+_33334773 0.47 ENSDART00000005879
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr7_-_25624212 0.47 ENSDART00000173505
CD99 molecule-like 2
chr7_-_25816498 0.47 ENSDART00000052989
ENSDART00000047951
acetylcholinesterase
chr15_+_26156180 0.46

chr14_+_38505346 0.46 ENSDART00000129958
ENSDART00000144599
heterogeneous nuclear ribonucleoprotein A0b
chr18_-_48498261 0.46 ENSDART00000146346
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6
chr1_+_44239727 0.45 ENSDART00000141145
si:dkey-9i23.16
chr6_+_29716538 0.45 ENSDART00000164849
prohibitin 2b
chr20_-_25839801 0.44

chr19_+_14197020 0.44 ENSDART00000166230
trophoblast glycoprotein a
chr15_-_25430003 0.44 ENSDART00000152651
clustered mitochondria (cluA/CLU1) homolog a
chr17_+_23102259 0.44 ENSDART00000178403
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr11_-_2563343 0.43 ENSDART00000008133
ENSDARG00000002897
chr24_+_24309660 0.43

chr23_+_35984675 0.43 ENSDART00000053295
homeobox C10a
chr23_-_20026717 0.43 ENSDART00000153828
ATPase, Ca++ transporting, plasma membrane 3b
chr18_+_20504641 0.42

chr25_-_21718647 0.41 ENSDART00000152014
ENSDART00000177876
ENSDARG00000051873
chr14_-_1081393 0.41

chr9_+_21908880 0.41

chr16_-_5821719 0.40 ENSDART00000136655
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3
chr17_-_43296680 0.40 ENSDART00000176637
echinoderm microtubule associated protein like 5
chr16_+_14135089 0.40

chr3_+_60724858 0.40 ENSDART00000044096
helicase with zinc finger
chr10_-_7712439 0.38 ENSDART00000159330
prenylcysteine oxidase 1
chr17_-_33336706 0.38 ENSDART00000040346
EFR3 homolog Ba (S. cerevisiae)
chr3_-_8608620 0.38

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0014075 response to amphetamine(GO:0001975) acetylcholine catabolic process(GO:0006581) response to amine(GO:0014075)
0.8 3.2 GO:1901388 transforming growth factor beta activation(GO:0036363) transforming growth factor beta production(GO:0071604) regulation of transforming growth factor beta production(GO:0071634) negative regulation of transforming growth factor beta production(GO:0071635) regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
0.6 1.8 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.5 2.8 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.5 1.4 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.4 1.2 GO:0009957 epidermal cell fate specification(GO:0009957)
0.3 1.0 GO:1903010 regulation of bone development(GO:1903010)
0.3 4.0 GO:0016203 muscle attachment(GO:0016203)
0.3 1.6 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.2 0.5 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.2 3.8 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.2 0.8 GO:1901490 regulation of lymphangiogenesis(GO:1901490) positive regulation of lymphangiogenesis(GO:1901492)
0.2 2.1 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259) negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.2 0.5 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 1.2 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.7 GO:0060394 SMAD protein complex assembly(GO:0007183) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.4 GO:0030328 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.1 0.7 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.9 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 0.3 GO:0032212 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.1 0.5 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.1 0.4 GO:0044209 AMP salvage(GO:0044209)
0.1 3.2 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 0.4 GO:0015860 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.1 0.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.9 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.3 GO:0044539 long-chain fatty acid import(GO:0044539)
0.1 0.9 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.9 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.1 2.4 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.1 1.3 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.1 0.9 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.1 1.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.3 GO:0048240 sperm capacitation(GO:0048240)
0.1 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.8 GO:0035775 pronephric glomerulus morphogenesis(GO:0035775)
0.1 0.9 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 0.9 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 1.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.3 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.0 1.0 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.8 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.9 GO:0007634 optokinetic behavior(GO:0007634)
0.0 1.2 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 1.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 1.2 GO:0007416 synapse assembly(GO:0007416)
0.0 1.6 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.8 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 1.0 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.9 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0051645 Golgi localization(GO:0051645)
0.0 0.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.9 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.8 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 1.0 GO:0007601 visual perception(GO:0007601)
0.0 0.1 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.0 0.3 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.1 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.0 0.3 GO:0009081 branched-chain amino acid metabolic process(GO:0009081)
0.0 1.1 GO:0006936 muscle contraction(GO:0006936)
0.0 1.5 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.7 GO:0033339 pectoral fin development(GO:0033339)
0.0 0.9 GO:0090630 activation of GTPase activity(GO:0090630)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:1902560 GMP reductase complex(GO:1902560)
0.2 2.4 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.2 3.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.2 1.7 GO:0016011 dystroglycan complex(GO:0016011)
0.2 1.8 GO:0031430 M band(GO:0031430)
0.1 1.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.5 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 1.3 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.3 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 2.5 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.2 GO:0005858 axonemal dynein complex(GO:0005858)
0.1 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 1.0 GO:0045095 keratin filament(GO:0045095)
0.0 2.7 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.9 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 2.5 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.8 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 1.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.5 GO:0072686 mitotic spindle(GO:0072686)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0003990 acetylcholinesterase activity(GO:0003990) cholinesterase activity(GO:0004104)
0.4 1.3 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.3 1.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.3 0.9 GO:0019960 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3 0.8 GO:0005521 lamin binding(GO:0005521)
0.3 1.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.2 1.0 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.2 1.0 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.2 3.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 3.0 GO:0008301 DNA binding, bending(GO:0008301)
0.2 1.2 GO:0043495 protein anchor(GO:0043495)
0.2 1.9 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.2 0.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 0.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.9 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.7 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.7 GO:0034632 retinol transporter activity(GO:0034632)
0.1 0.4 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.1 0.4 GO:0004001 adenosine kinase activity(GO:0004001)
0.1 1.7 GO:0043236 laminin binding(GO:0043236)
0.1 0.9 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 0.3 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.1 0.4 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.1 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.9 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 0.5 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.8 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 1.7 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 1.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.2 GO:0045503 dynein light chain binding(GO:0045503)
0.1 0.9 GO:0098631 protein binding involved in cell adhesion(GO:0098631)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.3 GO:0004691 AMP-activated protein kinase activity(GO:0004679) cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.5 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.6 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 3.3 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.4 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.6 GO:0008320 protein transmembrane transporter activity(GO:0008320) macromolecule transmembrane transporter activity(GO:0022884)
0.0 1.4 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 2.0 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.0 GO:0008201 heparin binding(GO:0008201)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 3.4 GO:0008017 microtubule binding(GO:0008017)
0.0 3.3 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 2.2 GO:0042393 histone binding(GO:0042393)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.2 0.9 PID ALK2 PATHWAY ALK2 signaling events
0.1 0.9 PID IL5 PATHWAY IL5-mediated signaling events
0.1 2.4 PID REELIN PATHWAY Reelin signaling pathway
0.1 2.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 3.2 PID FGF PATHWAY FGF signaling pathway
0.1 2.8 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.5 3.2 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.2 2.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 1.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 1.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 3.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 0.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 0.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 0.4 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.8 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.5 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)