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Results for nr6a1a

Z-value: 1.14

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Transcription factors associated with nr6a1a

Gene Symbol Gene ID Gene Info
ENSDARG00000101508 nuclear receptor subfamily 6, group A, member 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr6a1adr10_dc_chr8_-_52952226_52952290-0.721.5e-03Click!

Activity profile of nr6a1a motif

Sorted Z-values of nr6a1a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of nr6a1a

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_-_36503296 3.17 ENSDART00000149211
interleukin 13 receptor, alpha 2
chr5_-_11471707 1.97 ENSDART00000166285
si:ch73-47f2.1
chr25_+_7318688 1.89 ENSDART00000166496
catalase
chr17_-_45021393 1.83

chr9_-_12687806 1.64 ENSDART00000058565
PTTG1 interacting protein b
chr10_+_33449922 1.58 ENSDART00000115379
ENSDART00000163458
ENSDART00000078012
zgc:153345
chr8_-_22265875 1.55 ENSDART00000134033
si:ch211-147a11.3
chr18_+_8954323 1.54 ENSDART00000134827
transmembrane protein 243, mitochondrial a
chr7_+_15781933 1.44 ENSDART00000161669
inner mitochondrial membrane peptidase subunit 1
chr19_-_5186692 1.39 ENSDART00000037007
triosephosphate isomerase 1a
chr1_+_23866532 1.39 ENSDART00000076519
dCTP pyrophosphatase 1
chr24_-_9844547 1.31

chr12_+_30673985 1.30 ENSDART00000160422
aldehyde dehydrogenase 18 family, member A1
chr5_+_22076136 1.28 ENSDART00000080877
tumor necrosis factor (ligand) superfamily, member 10 like 4
chr11_+_44909949 1.24 ENSDART00000173116
ENSDART00000167011
ENSDART00000167226
pyrroline-5-carboxylate reductase 1b
chr2_-_50491234 1.19 ENSDART00000165678
MCM6 minichromosome maintenance deficient 6, like
chr2_-_22631167 1.13 ENSDART00000168653
ENSDART00000158558
family with sequence similarity 110, member B
ENSDARG00000098356
chr14_+_35074248 1.07 ENSDART00000084914
tRNA methyltransferase 12 homolog (S. cerevisiae)
chr21_-_804453 1.05

chr8_-_26690715 1.01 ENSDART00000135215
transmembrane protein 51a
chr1_+_49170967 1.00 ENSDART00000164936
lymphoid enhancer-binding factor 1
chr5_-_36503236 0.99 ENSDART00000149211
interleukin 13 receptor, alpha 2
chr24_+_34183462 0.99 ENSDART00000143995
zgc:92591
chr7_+_24855467 0.98 ENSDART00000077217
zgc:101765
chr8_-_22266041 0.97 ENSDART00000134033
si:ch211-147a11.3
chr1_-_7882397 0.96 ENSDART00000114613
pentatricopeptide repeat domain 1
chr10_-_36849540 0.91

chr3_-_49031058 0.90 ENSDART00000154561
mitochondrial ribosomal protein L12
chr18_-_20619155 0.90 ENSDART00000151864
BCL2-like 13 (apoptosis facilitator)
chr11_+_24076576 0.89 ENSDART00000171491
RAS (RAD and GEM)-like GTP-binding 1
chr3_-_58400454 0.89 ENSDART00000052179
cerebellar degeneration-related protein 2a
chr10_-_36849596 0.89

chr7_-_31346991 0.89 ENSDART00000111388
immunoglobulin superfamily, DCC subclass, member 3
chr8_+_15213841 0.88 ENSDART00000063717
ENSDARG00000043402
chr14_-_33138710 0.87 ENSDART00000132813
lysosomal-associated membrane protein 2
chr24_-_9838947 0.86 ENSDART00000138576
zgc:171977
chr11_+_26895952 0.86 ENSDART00000158411
ENSDART00000173374
ENSDART00000129736
histone deacetylase 11
chr15_-_16137131 0.85

chr11_-_7786415 0.84 ENSDART00000154569
ENSDARG00000097035
chr8_+_26838596 0.83

chr24_+_34183557 0.83 ENSDART00000143995
zgc:92591
chr20_+_28006043 0.83

chr15_+_30246345 0.80 ENSDART00000100214
nuclear fragile X mental retardation protein interacting protein 2
chr13_-_23825684 0.79 ENSDART00000133646
phosphatase and actin regulator 2
chr11_-_18637482 0.78 ENSDART00000156276
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b
chr7_-_31346844 0.78 ENSDART00000111388
immunoglobulin superfamily, DCC subclass, member 3
chr21_-_32341308 0.78 ENSDART00000112550
mitogen-activated protein kinase 9
chr14_+_25927045 0.77 ENSDART00000168673
ENSDART00000128971
GM2 ganglioside activator
chr13_-_11630642 0.77 ENSDART00000102381
ubiquitin-conjugating enzyme E2D 3
chr8_+_29733037 0.76 ENSDART00000133955
mitogen-activated protein kinase 4
chr15_-_16950049 0.76

chr7_-_25252260 0.74 ENSDART00000173657
ENSDARG00000105572
chr6_+_42340776 0.73 ENSDART00000015277
glutathione peroxidase 1b
chr13_-_8360779 0.72 ENSDART00000058107
multiple coagulation factor deficiency 2
chr10_-_16910230 0.72 ENSDART00000171755
ENSDART00000170953
stomatin (EPB72)-like 2
chr16_-_19155418 0.71 ENSDART00000134796
formin homology 2 domain containing 3b
chr24_+_17190448 0.71 ENSDART00000159724
ENSDART00000081851
ENSDART00000018868
protein disulfide isomerase family A, member 4
chr18_-_21199617 0.71 ENSDART00000060166
glutamic-oxaloacetic transaminase 2a, mitochondrial
chr2_+_38959335 0.70 ENSDART00000109219
RAS (RAD and GEM)-like GTP binding 2
chr7_-_31346802 0.70 ENSDART00000111388
immunoglobulin superfamily, DCC subclass, member 3
chr22_+_1643493 0.69 ENSDART00000167767
ENSDARG00000098230
chr5_+_61711614 0.69 ENSDART00000082965
active BCR-related
chr1_-_46260853 0.67

chr17_-_42523585 0.67 ENSDART00000154755
protein kinase D3
chr14_+_29932533 0.67 ENSDART00000017122
N-acylsphingosine amidohydrolase (acid ceramidase) 1a
chr12_-_4597113 0.66 ENSDART00000110514
proline rich 12a
chr16_+_29574449 0.66 ENSDART00000148450
cathepsin S, ortholog2, tandem duplicate 1
chr8_-_26690680 0.66 ENSDART00000135215
transmembrane protein 51a
chr13_-_11630475 0.66 ENSDART00000035505
ubiquitin-conjugating enzyme E2D 3
chr3_+_12087549 0.65

chr19_+_24334831 0.65 ENSDART00000090200
SNAP-associated protein
chr1_-_7968497 0.65 ENSDART00000141407
ENSDART00000148067
actin, beta 1
chr22_-_6723094 0.64

chr25_+_7318825 0.64 ENSDART00000159748
catalase
chr10_+_43289261 0.64 ENSDART00000024644
X-ray repair complementing defective repair in Chinese hamster cells 4
chr16_-_17289585 0.64 ENSDART00000135146
glyceraldehyde-3-phosphate dehydrogenase
chr9_+_8919663 0.63 ENSDART00000134954
carbohydrate kinase domain containing
chr4_-_71644701 0.62 ENSDART00000174178
si:cabz01021430.2
chr4_+_8007952 0.62 ENSDART00000014036
optineurin
chr25_+_16796766 0.61

chr23_-_27647386 0.61

chr17_-_42523635 0.61 ENSDART00000154755
protein kinase D3
chr17_+_18217416 0.61 ENSDART00000156616
ENSDARG00000097921
chr8_-_11806733 0.60 ENSDART00000064017
Rap guanine nucleotide exchange factor (GEF) 1a
chr10_-_36849472 0.60

chr8_-_22265802 0.60 ENSDART00000134033
si:ch211-147a11.3
chr17_+_5680342 0.60 ENSDART00000156089
ENSDARG00000096839
chr5_-_40524177 0.59 ENSDART00000083561
myotubularin related protein 12
chr14_-_33114322 0.58 ENSDART00000173267
transmembrane protein 255A
chr9_-_10833577 0.57 ENSDART00000078348
ENSDART00000134911
si:ch1073-416j23.1
chr15_+_28477741 0.57 ENSDART00000057257
phosphatidylinositol transfer protein, alpha a
chr6_-_7529384 0.57 ENSDART00000091836
ENSDART00000151697
ubinuclein 2a
chr10_-_42302932 0.57 ENSDART00000076693
ENSDART00000073631
STAM binding protein a
chr3_-_58400345 0.57 ENSDART00000052179
cerebellar degeneration-related protein 2a
chr1_-_42915971 0.57

chr18_+_6747156 0.56 ENSDART00000111343
lipase maturation factor 2a
chr14_-_21320696 0.56 ENSDART00000043162
receptor accessory protein 2
chr11_+_26125813 0.56 ENSDART00000088800
phosphopantothenoylcysteine synthetase
chr7_-_7533176 0.55 ENSDART00000173376
inturned planar cell polarity protein
chr13_+_42183685 0.55 ENSDART00000158367
insulin-degrading enzyme
chr7_+_55648832 0.55 ENSDART00000082780
acyl-CoA synthetase family member 3
chr19_-_6503643 0.55

chr13_-_8979137 0.54 ENSDART00000058056
mitochondrial ribosomal protein S26
chr8_+_13757180 0.54

chr8_-_54103635 0.53

chr23_+_25808393 0.53

chr5_+_40599287 0.52 ENSDART00000137545
ENSDARG00000093616
chr10_+_33450122 0.52 ENSDART00000115379
ENSDART00000163458
ENSDART00000078012
zgc:153345
chr24_+_24999138 0.52 ENSDART00000152095
ENSDART00000154988
ENSDART00000156098
ENSDARG00000096452
chr11_-_18637646 0.52 ENSDART00000156276
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b
chr2_-_59019569 0.51

chr7_+_7261692 0.51 ENSDART00000102629
nitrilase 1
chr13_+_50167246 0.51 ENSDART00000178572
ENSDARG00000108623
chr13_+_25722545 0.50

chr10_-_36849734 0.50

chr8_+_13757024 0.50

chr5_-_54578261 0.50 ENSDART00000016995
ENSDART00000134937
splicing regulatory glutamine/lysine-rich protein 1
chr11_+_26896056 0.49 ENSDART00000158411
ENSDART00000173374
ENSDART00000129736
histone deacetylase 11
chr4_+_16020464 0.49 ENSDART00000144611
ENSDARG00000093983
chr12_-_18286666 0.49 ENSDART00000078767
target of myb1 like 2 membrane trafficking protein
chr22_+_25059272 0.48 ENSDART00000177284
ribosome binding protein 1b
chr9_-_21427035 0.48 ENSDART00000146764
COX17 cytochrome c oxidase copper chaperone
chr14_-_36072158 0.48 ENSDART00000128244
ankyrin repeat and SOCS box containing 5a
chr21_+_15617110 0.47 ENSDART00000015841
glutathione S-transferase theta 1b
chr5_-_15921657 0.47

chr1_+_16834347 0.47 ENSDART00000005593
ENSDART00000140076
caspase 3, apoptosis-related cysteine peptidase a
chr2_+_58448918 0.46 ENSDART00000098173
VAMP (vesicle-associated membrane protein)-associated protein A, like
chr14_+_35074075 0.46 ENSDART00000084914
tRNA methyltransferase 12 homolog (S. cerevisiae)
chr9_-_10833656 0.46 ENSDART00000078348
ENSDART00000134911
si:ch1073-416j23.1
chr12_+_33294613 0.46 ENSDART00000129458
fatty acid synthase
chr17_+_18097490 0.45 ENSDART00000144894
B-cell CLL/lymphoma 11Ba (zinc finger protein)
chr5_-_47521160 0.45 ENSDART00000144252
ENSDARG00000095715
chr17_+_28532738 0.44

chr9_+_24255311 0.44 ENSDART00000166303
leucine rich repeat (in FLII) interacting protein 1a
chr9_-_22377136 0.44 ENSDART00000110933
ENSDARG00000076693
chr15_-_31104074 0.44 ENSDART00000157005
neurofibromin 1a
chr7_-_67508752 0.44 ENSDART00000167891
ENSDARG00000099896
chr21_-_21142020 0.44 ENSDART00000079678
FtsJ RNA methyltransferase homolog 1 (E. coli)
chr12_+_11314303 0.44 ENSDART00000129495
si:rp71-19m20.1
chr6_-_11127409 0.44 ENSDART00000151125
pericentrin
chr14_+_15728850 0.43 ENSDART00000161348
PRELI domain containing 1a
chr7_+_61450760 0.43 ENSDART00000165864
acyl-CoA oxidase 3, pristanoyl
chr25_-_28636834 0.42 ENSDART00000138087
cytochrome c oxidase subunit Vaa
chr15_-_30247084 0.42 ENSDART00000154069
ENSDARG00000097908
chr9_-_21427331 0.42 ENSDART00000102143
COX17 cytochrome c oxidase copper chaperone
chr5_-_54578223 0.42 ENSDART00000016995
ENSDART00000134937
splicing regulatory glutamine/lysine-rich protein 1
chr24_-_10253650 0.41 ENSDART00000127568
ENSDART00000106260
ANKH inorganic pyrophosphate transport regulator a
chr2_+_25212281 0.41 ENSDART00000078838
RAB3A, member RAS oncogene family, a
chr24_+_17190237 0.41 ENSDART00000126435
protein disulfide isomerase family A, member 4
chr12_-_18286637 0.40 ENSDART00000078767
target of myb1 like 2 membrane trafficking protein
chr18_-_2954175 0.39 ENSDART00000166382
chloride channel, nucleotide-sensitive, 1A
chr25_-_34638406 0.38 ENSDART00000123853
histone 1, H4, like
chr13_+_50167216 0.38 ENSDART00000178572
ENSDARG00000108623
chr10_-_16910257 0.38 ENSDART00000171755
ENSDART00000170953
stomatin (EPB72)-like 2
chr4_+_70728926 0.38

chr14_+_4071250 0.38 ENSDART00000162015
solute carrier family 25, member 51b
chr18_+_40481566 0.38 ENSDART00000098806
UDP glucuronosyltransferase 5 family, polypeptide C3
chr15_+_26667763 0.37 ENSDART00000155352
ENSDARG00000074561
chr5_-_68765495 0.37 ENSDART00000097251
ENSDARG00000067564
chr5_-_68765567 0.37 ENSDART00000097251
ENSDARG00000067564
chr9_+_33247126 0.37

chr22_-_6723168 0.37

chr1_+_15928362 0.36 ENSDART00000149026
ENSDART00000159785
ENSDART00000164899
pericentriolar material 1
chr2_+_32760638 0.36 ENSDART00000022909
kelch-like family member 18
chr20_-_33887129 0.35 ENSDART00000020183
family with sequence similarity 102, member B, b
chr21_+_19283166 0.35 ENSDART00000063621
abraxas 2a, BRISC complex subunit
chr25_+_28636948 0.35

chr7_-_41446221 0.35 ENSDART00000099121
ADP-ribosylation factor-like 8
chr3_+_31530419 0.34 ENSDART00000113441
myosin, light chain kinase 5
chr3_+_22914688 0.34 ENSDART00000156472
beta-1,4-N-acetyl-galactosaminyl transferase 2, tandem duplicate 2
chr5_-_54169271 0.34 ENSDART00000056213
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr16_-_34240818 0.34 ENSDART00000054026
regulator of chromosome condensation 1
chr1_+_51998508 0.33 ENSDART00000134658
solute carrier family 44 (choline transporter), member 1a
chr23_-_32239909 0.33

chr1_+_51998406 0.33 ENSDART00000134658
solute carrier family 44 (choline transporter), member 1a
chr22_+_18218979 0.32

chr2_+_52639159 0.32 ENSDART00000006216
phospholipid phosphatase 2a
chr8_-_54103762 0.32

chr20_-_51843197 0.31 ENSDART00000129965
ENSDARG00000091595
chr5_+_32751876 0.31

chr6_-_33940201 0.30 ENSDART00000132762
aldo-keto reductase family 1, member A1b (aldehyde reductase)
chr7_-_46940193 0.30 ENSDART00000161558
ENSDARG00000099964
chr15_+_28477893 0.30 ENSDART00000057257
phosphatidylinositol transfer protein, alpha a
chr21_-_43641419 0.30 ENSDART00000151486
ENSDART00000151115
si:ch1073-263o8.2
chr15_+_6776788 0.30 ENSDART00000152653
ENSDARG00000096597
chr9_-_21427247 0.30 ENSDART00000146764
COX17 cytochrome c oxidase copper chaperone
chr13_-_42598533 0.30 ENSDART00000160472
calpain 1, (mu/I) large subunit a
chr18_+_40481599 0.30 ENSDART00000098806
UDP glucuronosyltransferase 5 family, polypeptide C3
chr9_-_7308912 0.29 ENSDART00000128352
MIT, microtubule interacting and transport, domain containing 1
chr4_+_9477541 0.29 ENSDART00000030738
lipase maturation factor 2b
chr11_+_15743714 0.29 ENSDART00000167191
pantothenate kinase 4
chr17_-_41000670 0.29 ENSDART00000124715
si:dkey-16j16.4
chr5_-_9443859 0.29

chr18_-_2954048 0.29 ENSDART00000166382
chloride channel, nucleotide-sensitive, 1A
chr5_-_979163 0.28

chr10_+_4717721 0.28 ENSDART00000161789
paralemmin 2
chr23_+_17176587 0.28 ENSDART00000053414
COMM domain containing 7
chr15_+_16950144 0.28 ENSDART00000049196
glycerophosphodiester phosphodiesterase domain containing 1
chr3_-_39163225 0.28 ENSDART00000102674
ENSDART00000167070
phospholipase C, delta 3a
chr1_-_55108003 0.27 ENSDART00000142069
ENSDART00000043933
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.5 1.4 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.4 1.5 GO:0071280 cellular response to copper ion(GO:0071280)
0.4 1.4 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.3 1.4 GO:0009223 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.3 3.5 GO:0042542 response to hydrogen peroxide(GO:0042542)
0.2 0.7 GO:0006531 aspartate metabolic process(GO:0006531)
0.2 1.0 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.2 0.9 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 1.0 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.2 0.6 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.2 0.5 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.2 0.6 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 0.4 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.9 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.8 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 0.4 GO:0099558 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.1 1.2 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.9 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 1.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.4 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.9 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.1 0.7 GO:0051639 actin filament network formation(GO:0051639)
0.1 2.0 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.8 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.6 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 0.3 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.1 0.6 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.1 0.2 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 4.4 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.7 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 1.4 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.3 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.0 0.2 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 1.4 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.7 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.3 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0006921 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 1.8 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.3 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.2 GO:0006895 phagolysosome assembly(GO:0001845) Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.0 0.6 GO:0060173 limb development(GO:0060173)
0.0 0.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.5 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.2 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.6 GO:0018198 peptidyl-cysteine modification(GO:0018198)
0.0 0.8 GO:0007254 JNK cascade(GO:0007254)
0.0 0.6 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.2 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.2 0.7 GO:0034709 methylosome(GO:0034709)
0.2 0.6 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.2 0.6 GO:0097433 dense body(GO:0097433)
0.1 0.6 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 1.2 GO:0042555 MCM complex(GO:0042555)
0.1 1.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 0.6 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 0.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.7 GO:0042788 polysomal ribosome(GO:0042788)
0.0 2.2 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 3.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 3.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.0 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.4 GO:0000786 nucleosome(GO:0000786)
0.0 3.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.7 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.6 GO:0005776 autophagosome(GO:0005776)
0.0 1.1 GO:0098800 inner mitochondrial membrane protein complex(GO:0098800)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.4 1.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.3 1.2 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.2 0.7 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.2 1.0 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 0.8 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 1.4 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2 0.7 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.2 1.5 GO:0016531 copper chaperone activity(GO:0016531)
0.2 0.6 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 0.4 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.1 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.4 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.4 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 4.2 GO:0019955 cytokine binding(GO:0019955)
0.1 1.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 1.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.5 GO:0033149 FFAT motif binding(GO:0033149)
0.1 2.8 GO:0004601 peroxidase activity(GO:0004601)
0.1 0.3 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 1.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.3 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 1.1 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.2 GO:0030553 cGMP-dependent protein kinase activity(GO:0004692) cGMP binding(GO:0030553)
0.1 1.9 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.1 1.0 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.2 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 2.0 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.1 0.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.2 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.1 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.5 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.5 GO:0000049 tRNA binding(GO:0000049)
0.0 0.0 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 2.4 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.2 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.3 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.3 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.9 GO:0030276 clathrin binding(GO:0030276)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 0.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 1.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 2.5 PID FOXO PATHWAY FoxO family signaling
0.1 1.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.6 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.6 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 1.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.7 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.7 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis