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Results for olig1_olig2+olig4

Z-value: 1.55

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Transcription factors associated with olig1_olig2+olig4

Gene Symbol Gene ID Gene Info
ENSDARG00000040948 oligodendrocyte transcription factor 1
ENSDARG00000040946 oligodendrocyte lineage transcription factor 2
ENSDARG00000052610 oligodendrocyte transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
olig2dr10_dc_chr9_-_32942783_32942789-0.901.8e-06Click!
olig4dr10_dc_chr13_+_45830454_45830473-0.879.3e-06Click!

Activity profile of olig1_olig2+olig4 motif

Sorted Z-values of olig1_olig2+olig4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of olig1_olig2+olig4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_-_27394361 6.00 ENSDART00000132740
protein phosphatase 3, catalytic subunit, gamma isozyme, a
chr19_-_27093095 5.67

chr2_-_39070943 5.54 ENSDART00000129963
retinol binding protein 1b, cellular
chr18_-_40718244 4.10 ENSDART00000077577
si:ch211-132b12.8
chr20_+_34021257 3.87 ENSDART00000146292
LIM homeobox transcription factor 1, alpha
chr9_+_28293831 3.85 ENSDART00000101338
isocitrate dehydrogenase 1 (NADP+), soluble
chr19_+_41419851 3.76 ENSDART00000138555
ENSDART00000158587
ENSDART00000049842
CAS1 domain containing 1
chr15_+_14656797 3.57 ENSDART00000162350
F-box protein 46
chr18_+_284210 3.54 ENSDART00000158040
La ribonucleoprotein domain family, member 6
chr5_-_27394324 3.53 ENSDART00000132740
protein phosphatase 3, catalytic subunit, gamma isozyme, a
chr9_-_12916555 3.49 ENSDART00000140691
si:ch211-167j6.3
chr21_-_13654658 3.24 ENSDART00000111666
neural proliferation, differentiation and control, 1a
chr19_-_41820114 3.19 ENSDART00000038038
split hand/foot malformation (ectrodactyly) type 1
chr20_-_22899048 2.93 ENSDART00000063609
FIP1 like 1a (S. cerevisiae)
chr4_-_72228164 2.88

chr16_-_39317068 2.70 ENSDART00000133642
glycerol-3-phosphate dehydrogenase 1-like
chr5_-_14022455 2.56 ENSDART00000177403
ENSDARG00000107645
chr2_-_39071026 2.45 ENSDART00000129963
retinol binding protein 1b, cellular
chr18_+_18124107 2.40 ENSDART00000151406
ENSDARG00000096293
chr6_-_50731449 2.27 ENSDART00000157153
phosphatidylinositol glycan anchor biosynthesis, class U
chr24_-_23639458 2.26 ENSDART00000090368
serum/glucocorticoid regulated kinase family, member 3
KN150663v1_-_3381 2.24

chr15_-_5913264 2.21 ENSDART00000155156
ENSDART00000155971
si:ch73-281n10.2
chr18_+_18890626 2.19 ENSDART00000019581
ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)
chr24_-_9549374 2.14 ENSDART00000093046
ubiquitin-like modifier activating enzyme 5
chr5_-_23741221 2.14 ENSDART00000042481
PHD finger protein 23a
chr13_-_51617720 2.13 ENSDART00000121457
limb bud and heart development
chr5_+_27659432 2.09 ENSDART00000087684
non-SMC condensin I complex, subunit H
chr15_+_14656886 2.08 ENSDART00000162350
F-box protein 46
chr20_+_6783996 2.07 ENSDART00000169966
insulin-like growth factor binding protein 3
chr1_-_17000212 2.03 ENSDART00000146258
cilia and flagella associated protein 97
chr7_-_24249672 1.99 ENSDART00000077039
fatty acid amide hydrolase 2b
chr13_+_11418060 1.96 ENSDART00000166908
desumoylating isopeptidase 2
chr13_+_11307037 1.96 ENSDART00000138312
zinc finger and BTB domain containing 18
chr16_+_53366182 1.95 ENSDART00000162926
si:ch211-269k10.5
chr7_+_9045376 1.95 ENSDART00000128530
small nuclear ribonucleoprotein polypeptide A'
chr5_-_39205454 1.92 ENSDART00000133231
RasGEF domain family, member 1Ba
chr2_-_39070886 1.90 ENSDART00000129963
retinol binding protein 1b, cellular
chr10_+_9804879 1.89

chr20_-_36776382 1.88 ENSDART00000062908
ribosomal protein L7-like 1
chr3_-_7275821 1.85 ENSDART00000132197
ENSDARG00000102658
chr9_-_7235236 1.84 ENSDART00000092435
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr10_-_33435736 1.83 ENSDART00000023509
spindle and kinetochore associated complex subunit 2
chr10_-_31129270 1.83 ENSDART00000146116
pannexin 3
chr20_-_31349892 1.82 ENSDART00000137236
hippocalcin-like 1
chr5_-_54091790 1.82 ENSDART00000150070
cyclin B1
chr21_+_11686037 1.81 ENSDART00000031786
glutaredoxin (thioltransferase)
chr14_+_31278584 1.81 ENSDART00000158875
ENSDART00000026195
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6a
chr8_-_53625018 1.80

chr2_-_7913468 1.80 ENSDART00000163175
DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)
chr22_-_6916274 1.79

chr12_+_20685139 1.75 ENSDART00000153261
ENSDARG00000096799
KN150460v1_-_33517 1.72

chr13_+_11306913 1.71 ENSDART00000138312
zinc finger and BTB domain containing 18
chr16_-_17678748 1.69 ENSDART00000017142
mannose-6-phosphate receptor (cation dependent)
chr10_+_6925373 1.69 ENSDART00000128866
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr1_+_48770997 1.68 ENSDART00000015007
TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr23_-_18851683 1.68 ENSDART00000169180
ENSDART00000006482
transient receptor potential cation channel, subfamily C, member 4 associated protein b
chr24_-_23639325 1.67 ENSDART00000090368
serum/glucocorticoid regulated kinase family, member 3
chr6_-_22842200 1.65 ENSDART00000160311
small ubiquitin-like modifier 2a
chr21_+_13291305 1.64 ENSDART00000134347
zgc:113162
chr10_-_31129217 1.63 ENSDART00000146116
pannexin 3
chr21_-_38670059 1.62 ENSDART00000065169
ENSDART00000113813
seven in absentia homolog 2 (Drosophila)-like
chr13_+_11417882 1.61 ENSDART00000034935
desumoylating isopeptidase 2
chr20_-_31349698 1.60 ENSDART00000137236
hippocalcin-like 1
chr19_+_41419985 1.59 ENSDART00000138555
ENSDART00000158587
ENSDART00000049842
CAS1 domain containing 1
chr17_+_23709781 1.59 ENSDART00000034913
zgc:91976
chr20_+_4034072 1.59 ENSDART00000092217
tetratricopeptide repeat domain 13
chr13_+_11306998 1.58 ENSDART00000138312
zinc finger and BTB domain containing 18
chr6_-_51811024 1.58 ENSDART00000031597
proteasome inhibitor subunit 1
chr2_+_41909094 1.58 ENSDART00000179428
ENSDARG00000107429
chr7_+_15059782 1.58 ENSDART00000165683
mesoderm posterior ba
chr8_-_11806733 1.56 ENSDART00000064017
Rap guanine nucleotide exchange factor (GEF) 1a
chr10_+_15066791 1.55 ENSDART00000140084
si:dkey-88l16.5
chr12_+_5067663 1.54 ENSDART00000166600
centrosomal protein 55 like
chr7_+_45747622 1.54 ENSDART00000163991
cyclin E1
chr19_+_10742387 1.53 ENSDART00000091813
argonaute RISC catalytic component 3b
chr8_-_11806698 1.53 ENSDART00000064017
Rap guanine nucleotide exchange factor (GEF) 1a
chr22_-_10861268 1.52 ENSDART00000145229
rho/rac guanine nucleotide exchange factor (GEF) 18b
chr20_-_34126039 1.51 ENSDART00000033817
SCY1-like, kinase-like 3
chr24_-_16835352 1.51 ENSDART00000005331
ENSDART00000128446
kelch-like family member 15
chr9_+_44327817 1.50

chr8_+_7625846 1.47 ENSDART00000175045
ENSDARG00000107577
chr5_+_51979524 1.46 ENSDART00000168317
amyloid beta (A4) precursor protein-binding, family A, member 1a
chr22_-_28276824 1.46 ENSDART00000147686
si:dkey-222p3.1
chr7_+_38395803 1.45 ENSDART00000013394
mitochondrial carrier homolog 2
chr20_+_52723371 1.43 ENSDART00000002787
ENSDART00000158230
pyrroline-5-carboxylate reductase 3
chr13_+_28785104 1.42

chr5_-_39598926 1.42 ENSDART00000175588
WD repeat and FYVE domain containing 3
chr22_+_1451958 1.42

chr24_-_9549419 1.40 ENSDART00000093046
ubiquitin-like modifier activating enzyme 5
chr2_+_24045890 1.40 ENSDART00000047073
oxidative stress responsive 1a
chr13_+_22691356 1.39 ENSDART00000144094
DNA replication helicase/nuclease 2
chr7_+_44463158 1.37 ENSDART00000066380
carbonic anhydrase VII
chr2_+_10265922 1.35 ENSDART00000143876
cytidylate kinase
chr24_+_36316070 1.35 ENSDART00000155260
retinoblastoma binding protein 8
chr1_+_13768098 1.33 ENSDART00000005067
recombination signal binding protein for immunoglobulin kappa J region a
chr11_+_36117256 1.33 ENSDART00000141529
ataxin 7-like 2a
chr21_+_20350218 1.33 ENSDART00000144366
si:dkey-30k6.5
chr20_-_23977077 1.32 ENSDART00000043316
katanin p60 (ATPase containing) subunit A 1
chr17_+_27988842 1.31 ENSDART00000155838
leucine zipper protein 1
chr13_+_22567761 1.31 ENSDART00000137467
si:ch211-134m17.9
chr21_+_13291242 1.30 ENSDART00000134347
zgc:113162
chr5_-_22099244 1.29 ENSDART00000161298
non-POU domain containing, octamer-binding
chr12_-_19063761 1.29 ENSDART00000153343
zinc finger CCCH-type containing 7B
KN150663v1_-_3817 1.28

chr25_+_16259634 1.28 ENSDART00000136454
TEA domain family member 1a
chr1_-_54586004 1.27 ENSDART00000152687
si:ch211-286b5.4
chr20_+_23707625 1.27

chr2_+_46210971 1.27

chr20_+_23707789 1.26

chr2_+_46210909 1.25

chr22_-_11024649 1.25 ENSDART00000105823
ENSDART00000159995
insulin receptor b
chr3_+_7877162 1.23 ENSDART00000057434
ENSDART00000170291
hook microtubule-tethering protein 2
chr13_-_51617421 1.23 ENSDART00000121457
limb bud and heart development
chr3_+_42667814 1.22 ENSDART00000172425
zinc finger, AN1-type domain 2A
chr3_+_25776714 1.22 ENSDART00000170324
target of myb1 membrane trafficking protein
chr12_+_5013049 1.21 ENSDART00000161548
kinesin family member 22
chr2_-_5233961 1.21 ENSDART00000163728
discs, large (Drosophila) homolog 1, like
chr19_+_34263554 1.20 ENSDART00000161290
peroxisomal biogenesis factor 1
chr21_+_20350152 1.20 ENSDART00000144366
si:dkey-30k6.5
chr11_+_25455772 1.20 ENSDART00000110224
MON1 secretory trafficking family member Bb
chr22_-_31089831 1.20

chr8_+_44448437 1.19 ENSDART00000143807
major histocompatibility complex class I LAA
chr17_+_13803088 1.19 ENSDART00000176632
ENSDARG00000107833
chr15_+_47207251 1.19 ENSDART00000154481
StAR-related lipid transfer (START) domain containing 10
chr3_-_15960491 1.18 ENSDART00000064838
LIM and SH3 protein 1
KN149790v1_-_67669 1.18 ENSDART00000163561
ENSDARG00000099322
chr2_+_24046083 1.18 ENSDART00000047073
oxidative stress responsive 1a
chr12_-_20494169 1.18 ENSDART00000105362
sorting nexin 11
chr20_+_34021116 1.18 ENSDART00000146292
LIM homeobox transcription factor 1, alpha
chr20_-_9135267 1.17 ENSDART00000125133
Myb-like, SWIRM and MPN domains 1
chr5_-_14022419 1.17 ENSDART00000177403
ENSDARG00000107645
chr24_-_31394710 1.17 ENSDART00000169556
ATP-binding cassette, sub-family D (ALD), member 3a
chr13_+_28655338 1.16 ENSDART00000039028
NSE4 homolog A, SMC5-SMC6 complex component
chr3_-_62156743 1.16 ENSDART00000101870
ENSDART00000175992
protein Z, vitamin K-dependent plasma glycoprotein a
chr14_+_35065189 1.16 ENSDART00000171565
zinc finger and BTB domain containing 3
chr1_+_18956542 1.15 ENSDART00000054575
transmembrane protein 192
chr24_-_36721857 1.15

chr24_+_16575167 1.14

chr6_-_51811058 1.14 ENSDART00000031597
proteasome inhibitor subunit 1
chr24_+_14451260 1.14 ENSDART00000137337
ENSDART00000091784
thiamine triphosphatase
chr21_+_11685992 1.12 ENSDART00000031786
glutaredoxin (thioltransferase)
chr25_+_4660989 1.12 ENSDART00000170640
myosin VC
chr24_+_28855974 1.11 ENSDART00000017427
RNA-binding region (RNP1, RRM) containing 3
chr19_-_23665476 1.10 ENSDART00000140665
growth factor receptor-bound protein 10a
chr10_-_14582293 1.10 ENSDART00000039161
haloacid dehalogenase-like hydrolase domain containing 2
chr3_-_29557642 1.10 ENSDART00000151679
si:ch73-233k15.2
chr7_-_24249630 1.10 ENSDART00000077039
fatty acid amide hydrolase 2b
chr25_-_26309873 1.09 ENSDART00000155698
ubiquitin specific peptidase 3
chr5_-_56640932 1.09 ENSDART00000149855
fer (fps/fes related) tyrosine kinase
chr21_+_20350334 1.09 ENSDART00000144366
si:dkey-30k6.5
chr8_-_47215582 1.09 ENSDART00000147606
peptidylprolyl isomerase H (cyclophilin H)
chr20_-_4033876 1.09 ENSDART00000113184
ARV1 homolog, fatty acid homeostasis modulator
chr20_+_52021000 1.09 ENSDART00000074330
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A
chr5_-_65564733 1.08 ENSDART00000178162
ENSDARG00000107190
chr20_+_26037296 1.08 ENSDART00000141265
zinc finger protein 106b
chr13_+_28655433 1.08 ENSDART00000039028
NSE4 homolog A, SMC5-SMC6 complex component
chr15_-_5912917 1.07

chr20_+_19094480 1.07 ENSDART00000152380
L-threonine dehydrogenase
chr1_-_43011866 1.07

chr2_-_58446028 1.06 ENSDART00000111651
ENSDARG00000078442
chr18_-_43890836 1.06 ENSDART00000087382
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr3_+_37648665 1.06 ENSDART00000151506
si:dkey-260c8.8
chr5_-_56641001 1.06 ENSDART00000149855
fer (fps/fes related) tyrosine kinase
chr3_+_22204475 1.06 ENSDART00000055676
ENSDARG00000038186
chr3_+_36830725 1.05 ENSDART00000150917
ENSDARG00000070174
chr2_-_38288904 1.04

chr7_+_13238684 1.04 ENSDART00000053535
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like
chr5_+_25408121 1.04

chr14_-_26160351 1.03

chr20_-_49067167 1.03 ENSDART00000163071
ENSDART00000170617
5'-3' exoribonuclease 2
chr9_-_7235272 1.03 ENSDART00000174720
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr7_+_45748086 1.03 ENSDART00000170294
cyclin E1
chr7_-_24567002 1.03 ENSDART00000139455
family with sequence similarity 113
chr3_+_54551887 1.02 ENSDART00000169663
ENSDARG00000098327
chr9_-_25517664 1.02 ENSDART00000060840
mediator complex subunit 4
chr7_+_22524917 1.02 ENSDART00000112169
RNA binding motif protein 4.2
chr20_-_26148523 1.02 ENSDART00000141626
general transcription factor IIH, polypeptide 5
chr8_+_7625791 1.02 ENSDART00000175045
ENSDARG00000107577
chr14_+_33723918 1.02 ENSDART00000015670
mediator complex subunit 7
chr7_-_24604255 1.01 ENSDART00000173920
adenosine deaminase domain containing 2
chr7_+_15197911 1.01 ENSDART00000046542
insulin-like growth factor 1b receptor
chr10_+_22566556 1.01 ENSDART00000079514
ephrin-B3a
chr1_-_51863300 1.00 ENSDART00000004233
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr10_+_19615343 1.00

chr21_-_39501604 1.00 ENSDART00000006971
septin 4a
chr9_+_21548044 0.99 ENSDART00000147619
N-6 adenine-specific DNA methyltransferase 2 (putative)
chr10_+_33629943 0.99 ENSDART00000130093
c10h21orf59 homolog (H. sapiens)
chr3_-_32457708 0.99

chr25_+_7067043 0.99 ENSDART00000179500
ENSDARG00000107609
chr21_+_599565 0.99 ENSDART00000177311
ENSDARG00000106379
chr13_+_22567886 0.99 ENSDART00000137467
si:ch211-134m17.9
chr13_-_23626319 0.98 ENSDART00000124152
regulator of G protein signaling 17
chr6_+_8916643 0.98

chr14_-_34293596 0.97 ENSDART00000128869
actin filament associated protein 1-like 1a
chr7_+_45748011 0.97 ENSDART00000170294
cyclin E1
chr2_-_58805035 0.95 ENSDART00000159735
MAU2 sister chromatid cohesion factor
chr25_+_7067115 0.95 ENSDART00000179500
ENSDARG00000107609
chr7_-_41446321 0.95 ENSDART00000099121
ADP-ribosylation factor-like 8

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0006097 glyoxylate cycle(GO:0006097)
0.9 3.5 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.8 2.3 GO:0071932 replication fork reversal(GO:0071932)
0.7 2.2 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.7 3.5 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.6 1.9 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.6 1.9 GO:0009193 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.6 3.7 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.5 2.3 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.4 1.2 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.4 1.6 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.4 1.1 GO:0006772 thiamine metabolic process(GO:0006772) thiamine diphosphate metabolic process(GO:0042357) thiamine-containing compound metabolic process(GO:0042723)
0.4 2.2 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.3 2.1 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.3 1.3 GO:0072314 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.3 2.9 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.3 0.9 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.3 2.1 GO:0016578 histone deubiquitination(GO:0016578)
0.3 0.9 GO:0051645 Golgi localization(GO:0051645)
0.3 1.4 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.3 1.8 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.2 3.1 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.2 0.7 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.2 3.0 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.2 0.7 GO:2000106 leukocyte apoptotic process(GO:0071887) regulation of leukocyte apoptotic process(GO:2000106)
0.2 1.1 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.2 3.6 GO:0072091 regulation of stem cell proliferation(GO:0072091)
0.2 1.5 GO:0045444 fat cell differentiation(GO:0045444)
0.2 0.6 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.2 0.6 GO:0034421 post-translational protein acetylation(GO:0034421)
0.2 1.6 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.2 1.2 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.2 1.3 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.2 0.8 GO:0010481 keratinocyte development(GO:0003334) epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.2 2.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.2 0.9 GO:0031507 heterochromatin assembly(GO:0031507)
0.2 0.7 GO:1990379 maintenance of blood-brain barrier(GO:0035633) lysophospholipid transport(GO:0051977) lipid transport across blood brain barrier(GO:1990379)
0.2 0.4 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.2 1.1 GO:0032366 intracellular sterol transport(GO:0032366)
0.2 0.5 GO:0000967 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.2 0.9 GO:0051447 negative regulation of meiotic nuclear division(GO:0045835) negative regulation of meiotic cell cycle(GO:0051447)
0.2 1.7 GO:0061458 gonad development(GO:0008406) reproductive structure development(GO:0048608) reproductive system development(GO:0061458)
0.2 1.3 GO:0051013 microtubule severing(GO:0051013)
0.2 1.0 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.2 1.6 GO:0035283 fourth ventricle development(GO:0021592) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.2 1.3 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.2 0.8 GO:0046292 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.2 1.4 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 0.6 GO:0071869 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.2 0.6 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 2.8 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.6 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 1.0 GO:0099633 protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
0.1 0.7 GO:0010922 positive regulation of phosphatase activity(GO:0010922) positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 0.9 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 2.0 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.1 2.0 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626) regulation of cellular response to insulin stimulus(GO:1900076)
0.1 1.0 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.7 GO:0030262 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.1 0.5 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.6 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.1 0.6 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 0.5 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 1.0 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.1 0.4 GO:1903798 regulation of production of small RNA involved in gene silencing by RNA(GO:0070920) regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798)
0.1 0.7 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 0.3 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 0.9 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.8 GO:0010867 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.5 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.1 0.4 GO:1903335 regulation of vacuolar transport(GO:1903335)
0.1 0.7 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 2.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 0.8 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 1.8 GO:0001966 thigmotaxis(GO:0001966)
0.1 4.0 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.1 2.0 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 2.4 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.1 0.5 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.1 0.4 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.4 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 0.7 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 0.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.3 GO:0032675 interleukin-6 production(GO:0032635) regulation of interleukin-6 production(GO:0032675) protein import into mitochondrial intermembrane space(GO:0045041)
0.1 1.1 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 1.2 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 2.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 4.5 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 1.8 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.2 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.1 0.2 GO:0005997 xylulose metabolic process(GO:0005997)
0.1 0.3 GO:0003262 endocardial progenitor cell migration to the midline involved in heart field formation(GO:0003262)
0.1 0.7 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.1 GO:0090208 positive regulation of triglyceride metabolic process(GO:0090208)
0.1 0.1 GO:1903010 regulation of bone development(GO:1903010)
0.1 0.4 GO:0018201 peptidyl-glycine modification(GO:0018201)
0.1 1.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.8 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 1.0 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 1.8 GO:0035329 hippo signaling(GO:0035329)
0.1 1.0 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 0.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 0.5 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.7 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.1 0.7 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.2 GO:1904357 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.1 0.4 GO:0046323 type B pancreatic cell proliferation(GO:0044342) glucose import(GO:0046323)
0.1 1.2 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.1 1.1 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1 0.2 GO:0097201 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264) negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.1 1.2 GO:0006623 protein targeting to vacuole(GO:0006623)
0.1 1.5 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.1 0.2 GO:0070265 necrotic cell death(GO:0070265) programmed necrotic cell death(GO:0097300)
0.1 0.9 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.7 GO:0090169 regulation of spindle assembly(GO:0090169) regulation of mitotic spindle assembly(GO:1901673)
0.1 0.4 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.1 0.7 GO:0070918 dsRNA fragmentation(GO:0031050) production of miRNAs involved in gene silencing by miRNA(GO:0035196) production of small RNA involved in gene silencing by RNA(GO:0070918) cellular response to dsRNA(GO:0071359)
0.1 0.3 GO:0007589 body fluid secretion(GO:0007589)
0.1 0.8 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.1 0.4 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.3 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.0 GO:0072425 G2 DNA damage checkpoint(GO:0031572) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.0 4.0 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 1.0 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.3 GO:0097354 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.4 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.0 1.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.5 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.8 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.6 GO:0070475 rRNA base methylation(GO:0070475)
0.0 5.5 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 1.2 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.9 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.4 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.7 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0036268 swimming(GO:0036268)
0.0 1.1 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.2 GO:0070828 heterochromatin organization(GO:0070828)
0.0 0.3 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.3 GO:0042026 protein refolding(GO:0042026)
0.0 1.5 GO:0003341 cilium movement(GO:0003341)
0.0 1.0 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.3 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.7 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.1 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.9 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.0 1.7 GO:0071599 otic vesicle development(GO:0071599)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.0 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 2.5 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.3 GO:0000054 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 0.5 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.2 GO:0006692 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 2.6 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 0.5 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.6 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 2.7 GO:0016042 lipid catabolic process(GO:0016042)
0.0 0.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.9 GO:0050922 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of chemotaxis(GO:0050922) negative regulation of axon guidance(GO:1902668)
0.0 0.1 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.0 1.1 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 0.7 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 2.2 GO:0006310 DNA recombination(GO:0006310)
0.0 0.2 GO:0051307 meiotic chromosome separation(GO:0051307)
0.0 4.4 GO:0051603 proteolysis involved in cellular protein catabolic process(GO:0051603)
0.0 0.3 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.1 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.2 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.1 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.7 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.1 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 0.3 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.0 GO:0072575 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.0 0.9 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.4 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.5 GO:0051170 nuclear import(GO:0051170)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 9.9 GO:0005955 calcineurin complex(GO:0005955)
0.7 4.5 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.6 2.3 GO:0005760 gamma DNA polymerase complex(GO:0005760)
0.4 2.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.4 3.5 GO:0005921 gap junction(GO:0005921)
0.4 1.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.3 1.7 GO:0000796 condensin complex(GO:0000796)
0.3 2.0 GO:0000439 core TFIIH complex(GO:0000439)
0.3 1.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205) Sec62/Sec63 complex(GO:0031207)
0.3 2.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.3 1.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.3 0.8 GO:0061574 ASAP complex(GO:0061574)
0.3 2.6 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.3 3.6 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2 2.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.2 1.9 GO:0005899 insulin receptor complex(GO:0005899)
0.2 2.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2 0.6 GO:0030914 STAGA complex(GO:0030914)
0.2 0.9 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.2 2.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 2.1 GO:0097431 mitotic spindle pole(GO:0097431)
0.2 5.2 GO:0035861 site of double-strand break(GO:0035861)
0.2 0.8 GO:0035517 PR-DUB complex(GO:0035517)
0.2 1.2 GO:0000938 GARP complex(GO:0000938)
0.2 0.8 GO:0000814 ESCRT II complex(GO:0000814)
0.1 0.4 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.1 1.9 GO:0070847 core mediator complex(GO:0070847)
0.1 1.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.7 GO:0070695 FHF complex(GO:0070695)
0.1 1.0 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 1.0 GO:0002102 podosome(GO:0002102)
0.1 0.4 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.1 8.9 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 2.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 0.8 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 1.0 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 0.8 GO:0000124 SAGA complex(GO:0000124)
0.1 0.2 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.1 0.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 0.4 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.1 1.4 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.5 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 2.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.6 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.4 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 1.7 GO:0043186 P granule(GO:0043186)
0.1 0.8 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 3.0 GO:0030496 midbody(GO:0030496)
0.1 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.4 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 0.3 GO:0031526 brush border membrane(GO:0031526)
0.1 4.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 2.1 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 1.0 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 2.9 GO:0000776 kinetochore(GO:0000776)
0.0 0.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.9 GO:0005686 U2 snRNP(GO:0005686)
0.0 2.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 3.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.0 1.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.7 GO:0016592 mediator complex(GO:0016592)
0.0 3.0 GO:0055037 recycling endosome(GO:0055037)
0.0 0.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.5 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 1.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.3 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.2 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.6 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 3.0 GO:0016607 nuclear speck(GO:0016607)
0.0 0.8 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.8 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.0 4.6 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 2.5 GO:0005770 late endosome(GO:0005770)
0.0 0.2 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.1 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 2.5 GO:0005813 centrosome(GO:0005813)
0.0 1.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0097546 ciliary base(GO:0097546)
0.0 0.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.6 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 9.9 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
1.3 3.9 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.8 2.3 GO:0016890 site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890)
0.7 2.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.7 2.1 GO:0070336 Y-form DNA binding(GO:0000403) double-strand/single-strand DNA junction binding(GO:0000406) flap-structured DNA binding(GO:0070336)
0.6 3.6 GO:0090624 endoribonuclease activity, cleaving miRNA-paired mRNA(GO:0090624)
0.5 2.0 GO:0030620 U2 snRNA binding(GO:0030620)
0.5 5.8 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.5 1.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.5 1.9 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.5 1.4 GO:0009041 uridylate kinase activity(GO:0009041)
0.4 1.6 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.4 3.5 GO:0022829 wide pore channel activity(GO:0022829)
0.4 2.3 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.4 1.1 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.3 0.9 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.3 3.5 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.3 0.8 GO:0030626 U12 snRNA binding(GO:0030626)
0.3 0.8 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.3 1.6 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 1.7 GO:0005537 mannose binding(GO:0005537)
0.2 1.9 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.2 0.9 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.2 0.7 GO:0035174 histone serine kinase activity(GO:0035174)
0.2 0.7 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.2 7.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 0.6 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.2 0.6 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.2 0.8 GO:0004046 aminoacylase activity(GO:0004046)
0.2 1.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 1.9 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.2 1.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 0.6 GO:0070042 rRNA (uridine-N3-)-methyltransferase activity(GO:0070042)
0.2 0.7 GO:0051978 lysophospholipid transporter activity(GO:0051978)
0.2 0.5 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.2 1.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 4.7 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.2 2.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 0.8 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.4 GO:0045547 polyprenyltransferase activity(GO:0002094) dehydrodolichyl diphosphate synthase activity(GO:0045547)
0.1 0.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.6 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.3 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 0.4 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.8 GO:0051920 peroxiredoxin activity(GO:0051920)
0.1 0.8 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 2.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 0.6 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1 0.5 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.7 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 1.3 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.8 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 1.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.1 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 6.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.3 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.3 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.1 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 1.8 GO:0031386 protein tag(GO:0031386)
0.1 1.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324) fatty acid transporter activity(GO:0015245)
0.1 0.2 GO:0047522 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 1.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.2 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.3 GO:0046922 peptide-O-fucosyltransferase activity(GO:0046922)
0.1 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.1 1.0 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.1 0.8 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.2 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.1 1.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.3 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.2 GO:0004738 pyruvate dehydrogenase activity(GO:0004738)
0.1 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.7 GO:0035198 miRNA binding(GO:0035198)
0.1 2.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.8 GO:0046527 glucosyltransferase activity(GO:0046527)
0.1 0.2 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 1.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.7 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.5 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 0.4 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.1 0.3 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 2.9 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.6 GO:0034595 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0 3.0 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.3 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.4 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.4 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 4.7 GO:0019783 ubiquitin-like protein-specific protease activity(GO:0019783)
0.0 0.3 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0016842 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) amidine-lyase activity(GO:0016842)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.7 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 1.0 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 6.4 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 1.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 1.5 GO:0003724 RNA helicase activity(GO:0003724)
0.0 1.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.1 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.8 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.4 GO:0008483 transaminase activity(GO:0008483)
0.0 3.1 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 1.4 GO:0030276 clathrin binding(GO:0030276)
0.0 0.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.6 GO:0004532 exoribonuclease activity(GO:0004532) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 1.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.0 GO:0019902 phosphatase binding(GO:0019902)
0.0 1.5 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.7 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0004806 triglyceride lipase activity(GO:0004806)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.3 4.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 2.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 0.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 2.8 PID AURORA B PATHWAY Aurora B signaling
0.1 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 3.3 PID PLK1 PATHWAY PLK1 signaling events
0.1 0.3 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 2.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 2.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 1.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 2.2 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.1 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.7 PID BMP PATHWAY BMP receptor signaling
0.0 0.8 PID P73PATHWAY p73 transcription factor network
0.0 0.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.1 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.2 PID FOXM1 PATHWAY FOXM1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.3 1.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 0.3 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.2 5.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.2 2.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 2.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 1.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 3.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.3 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 1.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 3.1 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 1.1 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 1.2 REACTOME KINESINS Genes involved in Kinesins
0.1 2.9 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.1 3.0 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 1.9 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 0.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 1.0 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 3.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.9 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 2.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.4 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 1.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 2.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.6 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.7 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.2 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 3.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.4 REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.0 0.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism