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Results for onecut2

Z-value: 0.75

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Transcription factors associated with onecut2

Gene Symbol Gene ID Gene Info
ENSDARG00000090387 one cut homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
onecut2dr10_dc_chr21_-_1716495_17165670.361.7e-01Click!

Activity profile of onecut2 motif

Sorted Z-values of onecut2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of onecut2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_-_14821305 2.34

chr14_+_7626822 1.24 ENSDART00000109941
CXXC finger protein 5b
chr11_+_36933891 1.21 ENSDART00000170542
ENSDARG00000100406
chr6_-_10593395 1.15 ENSDART00000020261
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr19_-_35512932 1.12

chr2_-_32521879 1.08 ENSDART00000056639
Fas apoptotic inhibitory molecule 2a
chr5_+_49103778 1.06 ENSDART00000155405
ENSDARG00000098045
chr21_-_20305406 1.05 ENSDART00000065659
retinol binding protein 4, like
chr4_-_9172622 0.96 ENSDART00000042963
carbohydrate (chondroitin 4) sulfotransferase 11
chr15_-_33688186 0.95

chr3_+_23557320 0.95 ENSDART00000046638
homeobox B8a
chr20_+_52740555 0.91 ENSDART00000110777
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr10_-_33212897 0.89 ENSDART00000081170
cut-like homeobox 1a
chr13_+_24271932 0.89 ENSDART00000043002
RAB1A, member RAS oncogene family b
chr2_+_5651428 0.84 ENSDART00000111220
Mab-21 domain containing 2
chr4_+_13811932 0.83 ENSDART00000067168
PDZ domain containing ring finger 4
chr6_-_6895376 0.80 ENSDART00000081761
bridging integrator 1b
chr4_-_17226968 0.78 ENSDART00000177956
ENSDART00000177406
ENSDARG00000106175
chr16_+_46526268 0.77 ENSDART00000134734
rapunzel 5
chr15_-_26619404 0.77 ENSDART00000150152
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr23_-_45250886 0.77 ENSDART00000163367
ENSDARG00000103727
chr16_+_22672315 0.76 ENSDART00000142241
Src homology 2 domain containing E
chr5_+_23675413 0.73 ENSDART00000051552
mannose-P-dolichol utilization defect 1a
chr11_-_11534819 0.73 ENSDART00000104254
keratin 15
chr7_-_25623974 0.71 ENSDART00000173602
CD99 molecule-like 2
chr21_+_19034242 0.70 ENSDART00000123309
NK6 homeobox 1
chr19_-_41887040 0.70 ENSDART00000062026
distal-less homeobox 5a
chr10_-_7827244 0.70 ENSDART00000111058
myeloid-specific peroxidase
chr2_+_45447068 0.70 ENSDART00000083957
ENSDART00000160867
calmodulin regulated spectrin-associated protein family, member 2b
chr6_+_13833991 0.69

chr4_-_10600228 0.66 ENSDART00000048003
tetraspanin 12
chr11_+_42821961 0.66 ENSDART00000013642
forkhead box G1b
chr13_+_28286826 0.65 ENSDART00000043658
solute carrier family 2 (facilitated glucose transporter), member 15a
chr15_-_35394535 0.64 ENSDART00000144153
mitochondrial fission factor
chr18_+_9762796 0.62

chr10_-_33678206 0.62 ENSDART00000128049
hormonally up-regulated Neu-associated kinase
chr23_-_17543731 0.59 ENSDART00000002398
tripartite motif containing 101
chr7_-_57727148 0.58

chr6_-_6895175 0.58 ENSDART00000149232
ENSDART00000150033
bridging integrator 1b
chr17_+_32550616 0.56

chr1_-_22466834 0.56 ENSDART00000144208
adhesion G protein-coupled receptor L3.1
chr6_+_38882803 0.55 ENSDART00000132798
bridging integrator 2b
chr5_-_45729685 0.54 ENSDART00000156577
si:ch211-130m23.5
chr3_-_28534446 0.54 ENSDART00000151670
F-box and leucine-rich repeat protein 16
chr19_+_19939410 0.54

chr8_+_37136126 0.53 ENSDART00000098636
colony stimulating factor 1b (macrophage)
chr11_-_30364563 0.52 ENSDART00000165501
solute carrier family 8 (sodium/calcium exchanger), member 1a
chr18_+_22367874 0.52

chr25_+_18866796 0.51 ENSDART00000017299
thymine DNA glycosylase, tandem duplicate 1
chr21_-_27845076 0.51 ENSDART00000132583
neurexin 2a
chr5_-_62592627 0.50 ENSDART00000131274
tubulin folding cofactor E-like b
chr4_-_9172550 0.49 ENSDART00000042963
carbohydrate (chondroitin 4) sulfotransferase 11
chr1_+_50395721 0.48 ENSDART00000134065
dpy-30 histone methyltransferase complex regulatory subunit
chr11_+_30569525 0.48

chr10_+_35479226 0.45 ENSDART00000147303
HERV-H LTR-associating 2a, tandem duplicate 1
chr8_-_23060397 0.45 ENSDART00000135764
si:dkey-70p6.1
chr1_+_45267035 0.44 ENSDART00000108528
Rho guanine nucleotide exchange factor (GEF) 7b
chr23_+_28843683 0.43 ENSDART00000132179
mannan-binding lectin serine peptidase 2
chr16_-_16793728 0.42 ENSDART00000143550
si:dkey-8k3.2
chr12_+_26376471 0.42 ENSDART00000022495
nudE neurodevelopment protein 1-like 1a
chr24_-_38068071 0.40 ENSDART00000041805
meteorin, glial cell differentiation regulator
chr8_-_14446883 0.40 ENSDART00000057644
LIM homeobox 4
chr19_-_19282688 0.40 ENSDART00000162708
palmitoyl-protein thioesterase 2
chr15_+_19523309 0.39 ENSDART00000132665
zgc:77784
chr17_-_49931552 0.37 ENSDART00000161008
filamin A interacting protein 1a
chr7_-_71192839 0.35 ENSDART00000124827
leucine-rich repeat LGI family, member 2a
chr6_-_6895263 0.34 ENSDART00000149232
bridging integrator 1b
chr18_-_25064913 0.33 ENSDART00000013082
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr14_-_2430754 0.33 ENSDART00000159004
si:ch73-233f7.8
chr20_-_6822668 0.32 ENSDART00000169569
insulin-like growth factor binding protein 1a
chr11_+_19894502 0.31 ENSDART00000103997
FEZ family zinc finger 2
chr14_-_32543646 0.30 ENSDART00000105726
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr7_+_25794014 0.29 ENSDART00000174010
ENSDART00000173815
ENSDARG00000105638
chr6_+_46429927 0.29 ENSDART00000064865
ENSDART00000133992
staufen double-stranded RNA binding protein 1
chr17_+_8018808 0.29 ENSDART00000131200
myc target 1b
chr10_-_24422257 0.29 ENSDART00000141332
ENSDART00000100772
solute carrier family 43 (amino acid system L transporter), member 2b
chr3_-_27989221 0.28 ENSDART00000151143
RNA binding protein, fox-1 homolog (C. elegans) 1
chr10_-_42157835 0.28 ENSDART00000141500
ENSDART00000156626
ENSDARG00000093535
chr3_-_22098046 0.28 ENSDART00000017750
myosin, light chain 4, alkali; atrial, embryonic
KN149707v1_-_2099 0.27

chr22_-_20141216 0.26 ENSDART00000128023
BTB (POZ) domain containing 2a
chr7_+_35243375 0.25 ENSDART00000160065
ENSDARG00000101818
chr3_-_6555471 0.24 ENSDART00000157771
ENSDART00000166758
small ubiquitin-like modifier 2b
chr4_-_2937706 0.23 ENSDART00000160308
phosphodiesterase 3A, cGMP-inhibited
chr14_+_21401757 0.23 ENSDART00000073707
syntaxin 3A
chr21_+_3951876 0.21 ENSDART00000167791
Rap guanine nucleotide exchange factor (GEF) 1b
chr4_-_10600179 0.21 ENSDART00000048003
tetraspanin 12
chr1_+_45266889 0.20 ENSDART00000163725
Rho guanine nucleotide exchange factor (GEF) 7b
chr2_-_39793399 0.20 ENSDART00000007333
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36a
chr6_-_2501966 0.19 ENSDART00000155109
hydroxypyruvate isomerase
chr16_+_43818521 0.18 ENSDART00000149154
si:dkey-122a22.2
chr17_+_41034649 0.18 ENSDART00000160049
mitochondrial ribosomal protein L33
chr2_-_57133471 0.17

chr5_+_19153421 0.17

chr3_-_27989425 0.16 ENSDART00000151143
RNA binding protein, fox-1 homolog (C. elegans) 1
chr4_-_13256905 0.15 ENSDART00000026593
ENSDART00000150577
glutamate receptor interacting protein 1
chr4_-_2937838 0.15 ENSDART00000160308
phosphodiesterase 3A, cGMP-inhibited
chr10_-_24422496 0.14 ENSDART00000141332
ENSDART00000100772
solute carrier family 43 (amino acid system L transporter), member 2b
chr15_+_29241472 0.12

chr12_-_34621359 0.12

chr7_-_33080261 0.11 ENSDART00000114041
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr8_-_18579947 0.11

chr18_-_17048300 0.10 ENSDART00000165479
hyaluronan synthase 3
chr1_-_20716842 0.10 ENSDART00000102782
glutamate receptor, ionotropic, AMPA 2a
chr6_+_12999420 0.10 ENSDART00000089725
INO80 complex subunit Db
chr4_-_2937524 0.09 ENSDART00000160308
phosphodiesterase 3A, cGMP-inhibited
chr10_-_15447374 0.08 ENSDART00000020665
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr18_-_44854305 0.07 ENSDART00000086823
signal recognition particle receptor (docking protein)
chr21_+_30050280 0.07

chr20_-_6822718 0.07 ENSDART00000169569
insulin-like growth factor binding protein 1a
chr13_-_32517896 0.06 ENSDART00000132820
BEN domain containing 3
chr1_-_53465275 0.06

chr18_-_25065264 0.03 ENSDART00000013082
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr16_-_14506818 0.03 ENSDART00000170957
cellular retinoic acid binding protein 2, a
chr16_+_26147677 0.02 ENSDART00000113534
mitochondrial ribosomal protein L17
chr13_-_15863571 0.00 ENSDART00000016430
IKAROS family zinc finger 1 (Ikaros)
chr5_-_23171454 0.00 ENSDART00000135153
TBC1 domain family member 8B
chr7_-_67741663 0.00

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.2 0.6 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.4 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 1.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.7 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.1 0.5 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 0.9 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.1 0.3 GO:0015865 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.1 0.4 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 0.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.7 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.1 0.5 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.4 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.7 GO:2000377 regulation of reactive oxygen species metabolic process(GO:2000377)
0.1 0.5 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.5 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.1 0.7 GO:0050796 pancreatic A cell differentiation(GO:0003310) regulation of insulin secretion(GO:0050796)
0.0 0.2 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.4 GO:0006956 complement activation(GO:0006956)
0.0 0.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.3 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 1.6 GO:0060048 cardiac muscle contraction(GO:0060048)
0.0 0.9 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 0.2 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.6 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.2 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.4 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.9 GO:0006414 translational elongation(GO:0006414)
0.0 0.8 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0010883 regulation of lipid storage(GO:0010883)
0.0 0.9 GO:1905037 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.2 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:0048899 anterior lateral line development(GO:0048899)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 1.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.7 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0072379 ER membrane insertion complex(GO:0072379)
0.0 1.5 GO:0008021 synaptic vesicle(GO:0008021)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.3 1.6 GO:0048156 tau protein binding(GO:0048156)
0.2 1.1 GO:0034632 retinol transporter activity(GO:0034632)
0.2 0.7 GO:0030507 spectrin binding(GO:0030507)
0.1 1.1 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.3 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.1 0.5 GO:0008263 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.1 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.4 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.7 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.4 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 0.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism