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Results for osr2

Z-value: 0.46

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Transcription factors associated with osr2

Gene Symbol Gene ID Gene Info
osr2
ENSDARG00000038006 odd-skipped related transciption factor 2

Activity profile of osr2 motif

Sorted Z-values of osr2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of osr2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr18_-_45750 1.38 ENSDART00000148821
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr7_-_33558939 1.14 ENSDART00000074729
uacab
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr14_+_35906366 0.78 ENSDART00000105602
elovl6
ELOVL fatty acid elongase 6
chr22_-_11596329 0.76 ENSDART00000063133
gcga
glucagon a
chr10_-_13281047 0.68 ENSDART00000001253
si:busm1-57f23.1
si:busm1-57f23.1
chr18_-_1084561 0.67 ENSDART00000032392
dhdhl
dihydrodiol dehydrogenase (dimeric), like
chr10_+_38568464 0.64 ENSDART00000109752
serpinh1a
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a
chr23_+_35996491 0.61 ENSDART00000127384
hoxc9a
homeobox C9a
chr16_+_35391136 0.55 ENSDART00000167140
si:dkey-34d22.1
si:dkey-34d22.1
chr6_-_40886902 0.55 ENSDART00000017968
ENSDART00000154100
sirt4
sirtuin 4
chr14_+_8198019 0.50 ENSDART00000123364
vegfba
vascular endothelial growth factor Ba
chr7_-_33559032 0.48 ENSDART00000074729
uacab
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr8_+_3391493 0.47 ENSDART00000085993
pxnb
paxillin b
chr18_-_1084697 0.46 ENSDART00000032392
dhdhl
dihydrodiol dehydrogenase (dimeric), like
chr22_-_4622401 0.40 ENSDART00000106166
rx1
retinal homeobox gene 1
chr16_+_35391089 0.39 ENSDART00000167140
si:dkey-34d22.1
si:dkey-34d22.1
chr2_+_4144790 0.36 ENSDART00000160806
mkxb
mohawk homeobox b
chr16_+_51696466 0.35

chr5_-_54383466 0.34

chr17_-_16079935 0.34

chr3_-_11409342 0.32

chr11_+_31022048 0.30 ENSDART00000160154
si:dkey-238i5.2
si:dkey-238i5.2
chr11_-_36017515 0.29 ENSDART00000122531
nfya
nuclear transcription factor Y, alpha
chr18_-_45892 0.29 ENSDART00000052641
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr16_+_21065200 0.29 ENSDART00000006429
hibadhb
3-hydroxyisobutyrate dehydrogenase b
chr3_-_27989221 0.24 ENSDART00000151143
rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr23_-_35904414 0.22 ENSDART00000103150
calcoco1a
calcium binding and coiled-coil domain 1a
chr19_+_47707575 0.17 ENSDART00000163591
ENSDART00000159860
ENSDART00000138909
ENSDART00000158588
ENSDART00000170847
tpmt.2
thiopurine S-methyltransferase, tandem duplicate 2
chr10_-_41742329 0.15 ENSDART00000150213
ggt1b
gamma-glutamyltransferase 1b
chr11_-_36017410 0.13 ENSDART00000122531
nfya
nuclear transcription factor Y, alpha
chr3_-_27989425 0.10 ENSDART00000151143
rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr8_-_18410629 0.09

chr7_-_41871376 0.08 ENSDART00000110907
itfg1
integrin alpha FG-GAP repeat containing 1
chr19_-_6215704 0.07 ENSDART00000104978
cica
capicua transcriptional repressor a
chr6_-_43297150 0.06 ENSDART00000154170
frmd4ba
FERM domain containing 4Ba
chr14_+_23419894 0.05 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr5_+_6054781 0.04 ENSDART00000060532
zgc:110796
zgc:110796
chr3_-_27989329 0.00 ENSDART00000151143
rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.3 1.6 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.2 0.6 GO:1901492 regulation of lymphangiogenesis(GO:1901490) positive regulation of lymphangiogenesis(GO:1901492)
0.1 0.5 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 0.8 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 0.5 GO:0061055 myotome development(GO:0061055)
0.1 0.3 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.1 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.8 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.6 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.6 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.4 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 1.7 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.1 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.6 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.8 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.8 GO:0005179 hormone activity(GO:0005179)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.7 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives