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Results for otx2a_otx1

Z-value: 0.53

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Transcription factors associated with otx2a_otx1

Gene Symbol Gene ID Gene Info
ENSDARG00000030703 orthodenticle homeobox 2a
ENSDARG00000094992 orthodenticle homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
otx1adr10_dc_chr1_+_50277442_502774940.647.9e-03Click!
otx1bdr10_dc_chr17_+_24300451_24300487-0.514.4e-02Click!

Activity profile of otx2a_otx1 motif

Sorted Z-values of otx2a_otx1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of otx2a_otx1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_-_34367105 1.92 ENSDART00000157625
mitogen-activated protein kinase-activated protein kinase 3
chr25_+_18866796 1.14 ENSDART00000017299
thymine DNA glycosylase, tandem duplicate 1
chr19_+_2013850 1.10 ENSDART00000048850
SH3-domain binding protein 5a (BTK-associated)
chr1_-_674449 0.99 ENSDART00000160564
cysteine/tyrosine-rich 1
chr5_-_64348528 0.89 ENSDART00000158856
annexin A1b
chr9_-_30437160 0.85 ENSDART00000147241
ENSDARG00000092870
chr3_+_34010958 0.84 ENSDART00000131802
si:dkey-204f11.64
chr5_+_45822196 0.79

chr1_-_44888989 0.73 ENSDART00000135089
activating transcription factor 7 interacting protein
chr24_+_9335428 0.70 ENSDART00000132688
si:ch211-285f17.1
chr21_-_44610563 0.67 ENSDART00000099528
sprouty homolog 4 (Drosophila)
chr20_+_1251702 0.64 ENSDART00000064447
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr17_-_8111181 0.64 ENSDART00000149873
ENSDART00000148403
Abelson helper integration site 1
chr7_+_38123920 0.63 ENSDART00000138669
centrosomal protein 89
chr24_-_8590572 0.63 ENSDART00000082349
transcription factor AP-2 alpha
chr8_+_31426328 0.61 ENSDART00000135101
selenoprotein P, plasma, 1a
chr2_-_23431625 0.57 ENSDART00000157318
ENSDARG00000097593
chr24_+_9335316 0.53 ENSDART00000132688
si:ch211-285f17.1
chr4_-_18466436 0.53 ENSDART00000150221
SCO2 cytochrome c oxidase assembly protein
chr9_-_38232999 0.53 ENSDART00000133998
3-hydroxyacyl-CoA dehydratase 2
chr17_+_10437343 0.50 ENSDART00000167188
mitogen-activated protein kinase binding protein 1
chr22_-_32553488 0.48 ENSDART00000104693
poly(rC) binding protein 4
chr15_+_926222 0.45 ENSDART00000156395
si:dkey-7i4.9
chr2_-_49114158 0.44

chr7_+_19857748 0.44 ENSDART00000146335
zgc:114045
chr16_+_46530388 0.44 ENSDART00000058324
rapunzel 4
chr19_+_47846675 0.43 ENSDART00000041114
proteasome subunit beta 2
chr6_+_16279737 0.42 ENSDART00000040035
coiled-coil domain containing 80 like 1
chr5_-_40451061 0.42 ENSDART00000083515
PDZ domain containing 2
chr7_+_19857885 0.42 ENSDART00000146335
zgc:114045
chr15_+_676493 0.42

chr6_+_37677155 0.41 ENSDART00000122199
ENSDART00000065127
cytoplasmic FMR1 interacting protein 1
chr7_+_19858190 0.41 ENSDART00000179395
ENSDART00000113793
ENSDART00000169603
zgc:114045
chr23_-_3816492 0.41 ENSDART00000136394
high mobility group AT-hook 1a
chr5_-_56691295 0.40 ENSDART00000112793
cell division cycle 26 homolog
chr4_-_29059042 0.40 ENSDART00000169971
ENSDARG00000099486
chr23_+_41129663 0.38

chr7_-_35161302 0.38 ENSDART00000026712
matrix metallopeptidase 2
chr19_-_7621797 0.36 ENSDART00000143958
limb and CNS expressed 1 like
chr6_-_53426323 0.36 ENSDART00000162791
macrophage stimulating 1
chr7_-_46510632 0.35

chr19_+_34582100 0.34 ENSDART00000135592
POC1 centriolar protein homolog B (Chlamydomonas), like
chr8_+_47909655 0.33

chr14_-_9274939 0.33

chr18_+_45680493 0.33 ENSDART00000109948
glutamine and serine rich 1
chr7_-_35136671 0.33 ENSDART00000074963
lysophosphatidylcholine acyltransferase 2
chr19_+_7234029 0.32 ENSDART00000080348
bromodomain containing 2a
chr14_-_4166292 0.32 ENSDART00000127318
FERM and PDZ domain containing 1b
chr8_-_49754713 0.32 ENSDART00000074840
zgc:136564
chr24_+_20391758 0.31 ENSDART00000082082
glycyl-tRNA synthetase
chr14_-_25688444 0.31 ENSDART00000172909
antioxidant 1 copper chaperone
chr10_+_39291358 0.31 ENSDART00000159501
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr21_-_36338704 0.31 ENSDART00000157826
membrane protein, palmitoylated 1
chr9_+_1968455 0.31

chr13_-_33269297 0.30

chr5_-_40310798 0.29 ENSDART00000133183
poly (ADP-ribose) polymerase family, member 8
chr5_-_32282404 0.29 ENSDART00000166698
leucine rich repeat and sterile alpha motif containing 1
chr9_-_2938937 0.28

chr18_-_25002972 0.28 ENSDART00000163449
chromodomain helicase DNA binding protein 2
chr7_-_35136817 0.27 ENSDART00000074963
lysophosphatidylcholine acyltransferase 2
chr10_+_32160464 0.27 ENSDART00000099880
wingless-type MMTV integration site family, member 11, related
chr11_-_27455242 0.27 ENSDART00000045942
PHD finger protein 2
chr20_-_35109185 0.27 ENSDART00000062761
consortin, connexin sorting protein b
chr2_+_49683715 0.27 ENSDART00000122742
ENSDART00000160783
RAR-related orphan receptor C b
chr13_+_30097568 0.27 ENSDART00000134691
ribosomal protein S24
chr4_-_20764499 0.27 ENSDART00000023337
N-acyl phosphatidylethanolamine phospholipase D
chr22_-_31722970 0.27 ENSDART00000128247
LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
chr21_-_2116499 0.25 ENSDART00000167307
ENSDARG00000102019
chr17_-_9869142 0.25 ENSDART00000008355
cofilin 2 (muscle)
chr4_+_67836787 0.25 ENSDART00000168400
zinc finger protein 1117
KN149874v1_-_3544 0.25 ENSDART00000165981
ENSDARG00000099481
chr18_+_9762796 0.24

chr21_-_25176853 0.24 ENSDART00000122513
replication factor C (activator 1) 2
chr4_+_28452948 0.23 ENSDART00000150879
zinc finger protein 1067
chr17_+_14878846 0.23 ENSDART00000010507
ENSDART00000131052
prostaglandin E receptor 2a (subtype EP2)
chr3_+_36282205 0.23 ENSDART00000170318
si:ch1073-443f11.2
chr7_-_39107780 0.22 ENSDART00000173659
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr21_+_43706830 0.22 ENSDART00000126190
dyskeratosis congenita 1, dyskerin
chr7_-_16346150 0.21 ENSDART00000128488
E2F transcription factor 8
chr4_+_11054808 0.21 ENSDART00000140362
coiled-coil domain containing 59
chr5_-_40310638 0.21 ENSDART00000133183
poly (ADP-ribose) polymerase family, member 8
chr13_+_41791642 0.21 ENSDART00000114741
polymerase (RNA) I polypeptide B
chr3_-_39287733 0.21

chr19_-_20203902 0.19 ENSDART00000172668
ENSDARG00000101330
chr23_-_3816422 0.19 ENSDART00000132205
high mobility group AT-hook 1a
chr21_-_20728623 0.19 ENSDART00000135940
ENSDART00000002231
growth hormone receptor b
chr3_-_15849644 0.19 ENSDART00000160668
NME/NM23 nucleoside diphosphate kinase 3
chr19_-_8961733 0.19 ENSDART00000039629
cugbp, Elav-like family member 3a
KN150529v1_+_16214 0.18 ENSDART00000177459
ENSDARG00000108298
chr7_-_46510731 0.18

chr18_+_23891068 0.18 ENSDART00000146490
ENSDARG00000092402
chr8_+_25594106 0.18

chr11_-_27455348 0.17 ENSDART00000045942
PHD finger protein 2
chr3_-_15850290 0.17 ENSDART00000160628
NME/NM23 nucleoside diphosphate kinase 3
chr22_-_16128314 0.16 ENSDART00000009464
solute carrier family 30 (zinc transporter), member 7
chr5_+_26246985 0.16 ENSDART00000076742
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr11_-_18073742 0.16

chr9_-_46475828 0.16 ENSDART00000165238
histone deacetylase 4
chr17_+_50622804 0.16 ENSDART00000049464
fermitin family member 2
chr1_-_37451594 0.16 ENSDART00000142811
high mobility group box 2a
chr4_-_29003925 0.16 ENSDART00000111294
zgc:174315
chr4_+_17364740 0.16 ENSDART00000136299
nucleoporin 37
chr10_+_26691086 0.15 ENSDART00000079174
HIV-1 Tat specific factor 1
chr3_+_32360862 0.15 ENSDART00000151329
transient receptor potential cation channel, subfamily M, member 4a
chr8_-_45422915 0.15 ENSDART00000150067
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b
chr3_-_12752075 0.15 ENSDART00000160522
coiled-coil domain containing 137
chr16_-_48458505 0.15 ENSDART00000159372
eukaryotic translation initiation factor 3, subunit H, a
chr1_+_35217331 0.15

chr16_-_6450531 0.14 ENSDART00000060550
ENSDART00000145663
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9
chr7_-_35136743 0.14 ENSDART00000074963
lysophosphatidylcholine acyltransferase 2
chr16_+_38209664 0.14 ENSDART00000160332
phosphatidylinositol 4-kinase, catalytic, beta
chr18_+_284567 0.14 ENSDART00000158040
La ribonucleoprotein domain family, member 6
chr3_+_1440282 0.13 ENSDART00000158633
polymerase (DNA-directed), delta interacting protein 3
chr18_-_10744619 0.13 ENSDART00000034817
RNA binding motif protein 28
chr9_-_1457681 0.13 ENSDART00000124777
ENSDART00000093412
oxysterol binding protein-like 6
chr20_-_42481675 0.13 ENSDART00000015801
discoidin, CUB and LCCL domain containing 1
chr2_+_58658615 0.13

chr23_-_36342779 0.12 ENSDART00000024354
cysteine sulfinic acid decarboxylase
chr5_-_40310702 0.12 ENSDART00000133183
poly (ADP-ribose) polymerase family, member 8
chr10_-_14530340 0.12 ENSDART00000101298
ENSDART00000138161
galactose-1-phosphate uridylyltransferase
chr2_+_55859099 0.12 ENSDART00000097753
ENSDART00000141688
nicotinamide riboside kinase 2
chr12_-_9046799 0.12 ENSDART00000125230
exocyst complex component 6
chr25_-_10533634 0.11 ENSDART00000153639
protein phosphatase 6, regulatory subunit 3
chr4_-_29488075 0.11 ENSDART00000167636
ENSDARG00000101492
chr19_-_26093745 0.11 ENSDART00000022676
asparagine synthetase
chr18_+_23891152 0.10 ENSDART00000146490
ENSDARG00000092402
chr11_+_18710724 0.10 ENSDART00000176141
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr25_-_14494641 0.10

chr19_-_5141645 0.10 ENSDART00000150980
chromodomain helicase DNA binding protein 4a
chr19_+_2803373 0.10 ENSDART00000160847
HGH1 homolog (S. cerevisiae)
chr18_+_10816190 0.09 ENSDART00000161990
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr8_-_19872014 0.09 ENSDART00000129193
TraB domain containing 2B
chr17_+_1950129 0.09 ENSDART00000110529
BUB1 mitotic checkpoint serine/threonine kinase Bb
chr8_+_53241686 0.08 ENSDART00000125232
nuclear receptor subfamily 2, group C, member 2
chr20_-_29028920 0.08 ENSDART00000153082
sushi domain containing 6
chr23_-_45686191 0.08

chr4_+_36180573 0.08 ENSDART00000161159
ENSDARG00000102102
chr23_+_21565625 0.07 ENSDART00000025487
isoprenylcysteine carboxyl methyltransferase
chr7_-_26246798 0.07 ENSDART00000058913
eukaryotic translation initiation factor 4A1A
chr1_+_30941618 0.07 ENSDART00000044214
WW domain binding protein 1-like b
chr18_+_10815994 0.07 ENSDART00000028938
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr3_+_15605866 0.07 ENSDART00000140160
ENSDARG00000094116
chr17_+_50622887 0.07 ENSDART00000134126
fermitin family member 2
chr25_-_10532989 0.07 ENSDART00000177834
protein phosphatase 6, regulatory subunit 3
chr15_+_20428823 0.07 ENSDART00000062676
SPT5 homolog, DSIF elongation factor subunit
chr21_-_44109455 0.07 ENSDART00000044599
organic anion transporter X
chr19_+_34581867 0.07 ENSDART00000135592
POC1 centriolar protein homolog B (Chlamydomonas), like
chr15_-_26998580 0.06 ENSDART00000027563
coiled-coil domain containing 9
chr10_-_14530112 0.06 ENSDART00000176126
galactose-1-phosphate uridylyltransferase
chr8_-_29842274 0.06 ENSDART00000086044
ENSDART00000167487
solute carrier family 20 (phosphate transporter), member 2
chr9_+_21340251 0.06 ENSDART00000133903
hydroxyacid oxidase 2 (long chain)
chr21_+_36896321 0.06 ENSDART00000086001
ADP-ribosylation factor-like 10
chr5_-_43160243 0.05

chr2_+_20946939 0.05 ENSDART00000128505
olfactomedin-like 2Bb
chr5_+_32282547 0.05 ENSDART00000135459
ribosomal protein L12
chr11_-_12686320 0.05 ENSDART00000081319
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
chr4_+_56350528 0.05 ENSDART00000167976
ENSDARG00000098469
chr1_-_17898961 0.05 ENSDART00000082063
family with sequence similarity 114, member A1
chr5_+_61136704 0.05 ENSDART00000113508
heterogeneous nuclear ribonucleoprotein U-like 1 like
chr10_+_39555088 0.04 ENSDART00000135756
kin of IRRE like 3 a
chr7_+_19779221 0.04 ENSDART00000052904
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr2_+_58658858 0.04

chr25_+_6607551 0.04 ENSDART00000176596
ENSDARG00000108452
chr3_-_15060501 0.04 ENSDART00000037906
HIRA interacting protein 3
chr19_-_2222108 0.04 ENSDART00000127578
TWIST neighbor
chr3_+_29849796 0.03 ENSDART00000151509
potassium voltage-gated channel, shaker-related subfamily, member 7
chr24_-_21750082 0.03

chr7_-_39107722 0.03 ENSDART00000173659
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr17_-_31041977 0.03 ENSDART00000104307
echinoderm microtubule associated protein like 1
chr1_+_51998547 0.03 ENSDART00000134658
solute carrier family 44 (choline transporter), member 1a
chr17_+_30431520 0.03 ENSDART00000153826
lipin 1
chr13_-_35924447 0.03 ENSDART00000134955
legumain
chr5_-_68408171 0.02 ENSDART00000109761
ENSDART00000156681
ENSDART00000167680
ENSDARG00000076888
chr10_+_3052919 0.02 ENSDART00000028870
ubiquitin-conjugating enzyme E2L 3a
chr11_+_6298048 0.02 ENSDART00000104409
ENSDART00000139882
RAN binding protein 3a
chr9_+_3547661 0.02 ENSDART00000008606
methyltransferase like 8
chr5_+_34863704 0.02 ENSDART00000131286
ER lipid raft associated 2
chr6_-_7937201 0.02

chr1_-_37451291 0.02 ENSDART00000142811
high mobility group box 2a
chr5_-_25133456 0.01 ENSDART00000051566
zgc:101016
chr19_+_44288538 0.01 ENSDART00000139684
lysophospholipase II
chr20_-_34868582 0.01

chr18_+_23890892 0.01 ENSDART00000146490
ENSDARG00000092402
chr1_-_44513922 0.01 ENSDART00000014727
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa
chr12_+_22558928 0.00 ENSDART00000077548
actin binding LIM protein family, member 2
chr18_-_19016801 0.00 ENSDART00000129776
von Willebrand factor A domain containing 9
chr3_-_5367142 0.00 ENSDART00000098927
thioredoxin 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0071887 positive regulation of adaptive immune response(GO:0002821) positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002824) negative regulation of phospholipase activity(GO:0010519) positive regulation of vesicle fusion(GO:0031340) type 2 immune response(GO:0042092) regulation of fatty acid biosynthetic process(GO:0042304) T-helper 2 cell differentiation(GO:0045064) leukocyte apoptotic process(GO:0071887) regulation of leukocyte apoptotic process(GO:2000106)
0.1 0.4 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 0.5 GO:0033119 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 0.8 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.1 1.1 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.1 0.4 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 1.9 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.1 0.6 GO:0044458 motile cilium assembly(GO:0044458)
0.1 1.1 GO:0061099 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 0.3 GO:0070292 N-acylphosphatidylethanolamine metabolic process(GO:0070292)
0.1 0.2 GO:0002706 regulation of lymphocyte mediated immunity(GO:0002706)
0.1 0.2 GO:0042023 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.1 0.3 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 0.7 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.1 0.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.7 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120) mRNA pseudouridine synthesis(GO:1990481)
0.1 0.4 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.2 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.4 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 0.6 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036) iridophore differentiation(GO:0050935)
0.0 0.6 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.2 GO:0060416 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.3 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.1 GO:0060333 positive regulation of cytokine-mediated signaling pathway(GO:0001961) interferon-gamma-mediated signaling pathway(GO:0060333) positive regulation of response to cytokine stimulus(GO:0060760)
0.0 0.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.1 GO:0090299 perichondral ossification(GO:0036073) regulation of neural crest formation(GO:0090299)
0.0 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0051754 meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177) meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.3 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.5 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.3 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.4 GO:0030282 bone mineralization(GO:0030282)
0.0 0.3 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:0040019 positive regulation of embryonic development(GO:0040019)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.8 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.2 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.5 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.6 GO:0005814 centriole(GO:0005814)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0102345 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.2 1.1 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.1 0.7 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.9 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.1 0.3 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.2 GO:0004953 icosanoid receptor activity(GO:0004953)
0.1 0.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.2 GO:0004903 growth hormone receptor activity(GO:0004903)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 1.1 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.3 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.5 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.2 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.9 PID CASPASE PATHWAY Caspase cascade in apoptosis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 0.7 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.4 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C