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Results for otx2b

Z-value: 1.22

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Transcription factors associated with otx2b

Gene Symbol Gene ID Gene Info
otx2b
ENSDARG00000011235 orthodenticle homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
otx2dr10_dc_chr17_-_44133970_441339940.802.2e-04Click!

Activity profile of otx2b motif

Sorted Z-values of otx2b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of otx2b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_+_26013873 9.09 ENSDART00000043932
atp2a1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr19_-_8961733 3.45 ENSDART00000039629
celf3a
cugbp, Elav-like family member 3a
chr9_-_43178744 2.82

chr11_-_29316162 2.82 ENSDART00000163958
arhgef10la
Rho guanine nucleotide exchange factor (GEF) 10-like a
chr1_-_44476084 2.66 ENSDART00000034549
zgc:111983
zgc:111983
chr14_-_4166292 2.66 ENSDART00000127318
frmpd1b
FERM and PDZ domain containing 1b
chr22_+_30234718 2.60 ENSDART00000172496
add3a
adducin 3 (gamma) a
chr5_-_28025315 2.57 ENSDART00000131729
tnc
tenascin C
chr15_-_2689005 2.56 ENSDART00000063325
cldnf
claudin f
chr9_+_26292183 2.43

chr7_-_33558939 2.43 ENSDART00000074729
uacab
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr3_+_45375639 2.33 ENSDART00000162799
crb3a
crumbs homolog 3a
chr23_+_35964754 2.21 ENSDART00000103147
hoxc12a
homeobox C12a
chr15_-_15532980 2.20 ENSDART00000004220
ENSDART00000131259
rab34a
RAB34, member RAS oncogene family a
chr7_+_67244332 2.10 ENSDART00000170322
rpl13
ribosomal protein L13
chr16_+_42925950 2.07 ENSDART00000159730
ENSDART00000014956
polr3glb
polymerase (RNA) III (DNA directed) polypeptide G like b
chr5_-_28025439 2.06 ENSDART00000131729
tnc
tenascin C
chr23_-_24468191 2.04 ENSDART00000044918
epha2b
eph receptor A2 b
chr11_-_4216204 2.02 ENSDART00000121716
ENSDARG00000086300
ENSDARG00000086300
chr14_-_36037883 1.99 ENSDART00000173006
gpm6aa
glycoprotein M6Aa
chr8_-_38357549 1.98 ENSDART00000129597
sorbs3
sorbin and SH3 domain containing 3
chr14_-_7774262 1.96 ENSDART00000045109
zgc:92242
zgc:92242
chr12_+_6065116 1.94 ENSDART00000139054
sgms1
sphingomyelin synthase 1
chr5_+_22006860 1.92 ENSDART00000080919
rpl36a
ribosomal protein L36A
chr10_+_32160464 1.88 ENSDART00000099880
wnt11r
wingless-type MMTV integration site family, member 11, related
chr17_+_16557246 1.86 ENSDART00000015729
ENSDART00000136874
foxn3
forkhead box N3
chr10_-_8029671 1.85 ENSDART00000141445
ewsr1a
EWS RNA-binding protein 1a
chr23_+_14058972 1.85 ENSDART00000090864
lmod3
leiomodin 3 (fetal)
chr13_-_39821399 1.79 ENSDART00000056996
sfrp5
secreted frizzled-related protein 5
chr15_+_33212930 1.78 ENSDART00000164928
mab21l1
mab-21-like 1
chr4_-_9172622 1.77 ENSDART00000042963
chst11
carbohydrate (chondroitin 4) sulfotransferase 11
chr15_-_18159904 1.72 ENSDART00000170874
phldb1b
pleckstrin homology-like domain, family B, member 1b
chr14_-_2682064 1.72 ENSDART00000161677
si:dkey-201i24.6
si:dkey-201i24.6
chr17_+_24613874 1.67 ENSDART00000093004
map4k3b
mitogen-activated protein kinase kinase kinase kinase 3b
chr15_-_18638643 1.58 ENSDART00000142010
ncam1b
neural cell adhesion molecule 1b
chr11_-_27455242 1.58 ENSDART00000045942
phf2
PHD finger protein 2
chr1_-_10391257 1.57 ENSDART00000102903
dmd
dystrophin
chr10_-_21096635 1.55 ENSDART00000091004
pcdh1a
protocadherin 1a
chr11_-_2133416 1.53 ENSDART00000170593
hoxc12b
homeobox C12b
chr16_-_41994015 1.53

chr25_-_4376129 1.52

chr7_+_38123920 1.50 ENSDART00000138669
cep89
centrosomal protein 89
chr21_+_21705138 1.50 ENSDART00000112068
defbl1
defensin, beta-like 1
chr23_+_2193582 1.48 ENSDART00000106336
cpeb2
cytoplasmic polyadenylation element binding protein 2
chr19_-_39048324 1.48 ENSDART00000086717
col16a1
collagen, type XVI, alpha 1
chr17_+_45931793 1.43 ENSDART00000155372
kif26ab
kinesin family member 26Ab
chr3_-_32190009 1.43

chr7_+_55883471 1.42 ENSDART00000073594
ankrd11
ankyrin repeat domain 11
chr2_-_42011586 1.40 ENSDART00000045763
keap1a
kelch-like ECH-associated protein 1a
chr21_-_20305406 1.39 ENSDART00000065659
rbp4l
retinol binding protein 4, like
chr20_-_21773202 1.38 ENSDART00000133286
si:ch211-207i1.2
si:ch211-207i1.2
chr13_-_22901327 1.37 ENSDART00000056523
hkdc1
hexokinase domain containing 1
chr6_-_13215384 1.35 ENSDART00000112883
fmnl2b
formin-like 2b
chr5_+_58824344 1.34 ENSDART00000148727
gtf2ird1
GTF2I repeat domain containing 1
chr11_-_27455348 1.33 ENSDART00000045942
phf2
PHD finger protein 2
chr17_-_31147256 1.32 ENSDART00000055754
pkdccb
protein kinase domain containing, cytoplasmic b
chr10_+_35535209 1.32 ENSDART00000109705
phldb2a
pleckstrin homology-like domain, family B, member 2a
chr11_-_3841178 1.29 ENSDART00000082425
gata2a
GATA binding protein 2a
chr12_-_22438379 1.24 ENSDART00000177715
CR925753.1
ENSDARG00000108493
chr7_+_71096788 1.23 ENSDART00000161871
sod3a
superoxide dismutase 3, extracellular a
chr17_+_50622804 1.18 ENSDART00000049464
fermt2
fermitin family member 2
chr4_+_5370319 1.16 ENSDART00000163797
ENSDARG00000014395
ENSDARG00000014395
chr9_+_7745593 1.16 ENSDART00000061716
mnx2a
motor neuron and pancreas homeobox 2a
chr14_+_34626233 1.15 ENSDART00000004550
rnf145a
ring finger protein 145a
chr4_-_17226968 1.13 ENSDART00000177956
ENSDART00000177406
BX547928.1
ENSDARG00000106175
chr9_-_19154264 1.13 ENSDART00000081878
pou1f1
POU class 1 homeobox 1
chr23_-_28099284 1.12 ENSDART00000024283
sp5l
Sp5 transcription factor-like
chr7_-_41209891 1.12 ENSDART00000174300
smarcd3b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b
chr16_+_11260802 1.10 ENSDART00000140674
cicb
capicua transcriptional repressor b
chr16_-_33105847 1.09

chr23_-_6707246 1.09 ENSDART00000023793
mipb
major intrinsic protein of lens fiber b
chr2_+_26273986 1.08 ENSDART00000137746
slc7a14a
solute carrier family 7, member 14a
chr7_-_13638486 1.06 ENSDART00000169828
rlbp1a
retinaldehyde binding protein 1a
chr17_+_10437343 1.06 ENSDART00000167188
mapkbp1
mitogen-activated protein kinase binding protein 1
chr7_-_33559032 1.04 ENSDART00000074729
uacab
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr6_+_36965023 1.03 ENSDART00000028895
negr1
neuronal growth regulator 1
chr8_-_23405325 1.02

chr15_-_26703761 1.02 ENSDART00000087632
ENSDARG00000079340
ENSDARG00000079340
chr3_+_45375698 1.01 ENSDART00000162799
crb3a
crumbs homolog 3a
chr3_+_23573114 1.00 ENSDART00000024256
hoxb6a
homeobox B6a
chr7_-_49322226 0.98 ENSDART00000174161
brsk2b
BR serine/threonine kinase 2b
chr17_-_31041977 0.97 ENSDART00000104307
eml1
echinoderm microtubule associated protein like 1
chr11_-_16080475 0.97 ENSDART00000027014
rab7
RAB7, member RAS oncogene family
chr15_-_6979997 0.95 ENSDART00000169944
si:ch73-311h14.2
si:ch73-311h14.2
chr23_-_3816492 0.95 ENSDART00000136394
hmga1a
high mobility group AT-hook 1a
chr1_+_16900546 0.95 ENSDART00000078889
helt
helt bHLH transcription factor
chr3_+_17947837 0.92 ENSDART00000021634
wfikkn2a
info WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2a
chr23_-_35096962 0.91 ENSDART00000122429
klf15
Kruppel-like factor 15
chr8_+_14343513 0.89 ENSDART00000057642
acbd6
acyl-CoA binding domain containing 6
chr17_+_16557298 0.88 ENSDART00000015729
ENSDART00000136874
foxn3
forkhead box N3
chr23_-_4175790 0.87 ENSDART00000109807
ENSDARG00000076299
ENSDARG00000076299
KN150196v1_+_15525 0.86

chr15_+_29183251 0.82 ENSDART00000153609
capns1b
calpain, small subunit 1 b
chr1_+_50348973 0.82

chr7_-_70466713 0.81

chr1_+_54403123 0.81 ENSDART00000152654
lgalsla
lectin, galactoside-binding-like a
chr20_-_46638031 0.81 ENSDART00000060685
tmed10
transmembrane p24 trafficking protein 10
chr7_-_28339836 0.76 ENSDART00000054366
scube2
signal peptide, CUB domain, EGF-like 2
chr11_+_25266623 0.76 ENSDART00000154213
tfe3b
transcription factor binding to IGHM enhancer 3b
chr19_-_39048402 0.74 ENSDART00000086717
col16a1
collagen, type XVI, alpha 1
KN150196v1_+_15459 0.74

chr2_-_48317047 0.74 ENSDART00000123040
pfkpb
phosphofructokinase, platelet b
chr11_+_30048913 0.73

chr5_-_13890202 0.72 ENSDART00000026120
ap3m2
adaptor-related protein complex 3, mu 2 subunit
chr5_+_29327479 0.72

chr4_+_15072119 0.72

chr15_-_23532475 0.70 ENSDART00000148804
pdzd3a
PDZ domain containing 3a
chr13_-_50299821 0.69 ENSDART00000170527
vent
ventral expressed homeobox
chr14_-_9274939 0.68

chr6_-_17699493 0.68 ENSDART00000154180
CR388029.1
ENSDARG00000097214
chr24_+_37645966 0.67 ENSDART00000061203
rhot2
ras homolog family member T2
chr5_+_19153421 0.66

chr17_+_50622887 0.65 ENSDART00000134126
fermt2
fermitin family member 2
chr15_+_46813538 0.64

chr21_+_13236509 0.64

chr13_-_47510290 0.63 ENSDART00000121817
fbln7
fibulin 7
chr11_+_2437479 0.63 ENSDART00000130886
NABP2
nucleic acid binding protein 2
chr2_-_2456819 0.62 ENSDART00000013794
ENSDART00000082155
ENSDART00000169871
ENSDART00000167202
dab1b
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr10_-_18510699 0.62

chr13_+_40689329 0.61 ENSDART00000129532
prkg1a
protein kinase, cGMP-dependent, type Ia
chr7_+_30698873 0.57 ENSDART00000155974
tjp1a
tight junction protein 1a
chr18_+_10815994 0.56 ENSDART00000028938
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr17_+_45931756 0.56 ENSDART00000155372
kif26ab
kinesin family member 26Ab
chr4_-_18447913 0.55 ENSDART00000141671
socs2
suppressor of cytokine signaling 2
chr14_-_29459799 0.55 ENSDART00000005568
pdlim3b
PDZ and LIM domain 3b
chr2_-_16548451 0.54 ENSDART00000152031
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr5_+_26217533 0.53

chr21_+_5293086 0.52

chr7_-_17527827 0.50 ENSDART00000128504
si:dkey-106g10.7
si:dkey-106g10.7
chr6_+_32428877 0.49

chr9_-_28588288 0.48 ENSDART00000104317
ENSDART00000064343
klf7b
Kruppel-like factor 7b
chr1_-_15814788 0.48 ENSDART00000169081
mtmr7b
myotubularin related protein 7b
chr14_+_43599635 0.47 ENSDART00000155539
CR786577.1
ENSDARG00000097875
chr18_+_10816190 0.46 ENSDART00000161990
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr13_+_42276937 0.46

chr5_+_42472789 0.45 ENSDART00000026020
wdr54
WD repeat domain 54
chr23_-_28099391 0.45 ENSDART00000024283
sp5l
Sp5 transcription factor-like
chr23_-_28099359 0.44 ENSDART00000024283
sp5l
Sp5 transcription factor-like
chr7_-_50244215 0.42 ENSDART00000073910
adamtsl5
ADAMTS like 5
chr13_-_50299643 0.39 ENSDART00000170527
vent
ventral expressed homeobox
chr5_+_69369417 0.37

chr10_-_21096686 0.35 ENSDART00000139733
pcdh1a
protocadherin 1a
chr17_-_20959288 0.35 ENSDART00000006676
phyhipla
phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr8_+_27724171 0.34 ENSDART00000046004
wnt2bb
wingless-type MMTV integration site family, member 2Bb
chr3_-_26013660 0.34

chr17_+_45932080 0.33 ENSDART00000157326
kif26ab
kinesin family member 26Ab
chr23_-_28099235 0.32 ENSDART00000024283
sp5l
Sp5 transcription factor-like
chr7_+_66660781 0.32 ENSDART00000082664
sbf2
SET binding factor 2
chr4_-_9172550 0.32 ENSDART00000042963
chst11
carbohydrate (chondroitin 4) sulfotransferase 11
chr1_-_37451594 0.30 ENSDART00000142811
hmgb2a
high mobility group box 2a
chr20_-_21773327 0.29 ENSDART00000133286
si:ch211-207i1.2
si:ch211-207i1.2
chr5_+_25346893 0.27

chr11_+_30049412 0.24

chr10_+_35610358 0.23 ENSDART00000077373
zdhhc20a
zinc finger, DHHC-type containing 20a
chr7_-_66641971 0.23

chr4_+_11465367 0.19 ENSDART00000008584
gdi2
GDP dissociation inhibitor 2
chr13_-_25068717 0.19 ENSDART00000057605
adka
adenosine kinase a
chr7_-_29871904 0.18 ENSDART00000173636
frmd5
FERM domain containing 5
chr2_-_48401640 0.16 ENSDART00000056277
gigfy2
GRB10 interacting GYF protein 2
chr11_+_36215760 0.16 ENSDART00000128245
ldlrad2
low density lipoprotein receptor class A domain containing 2
chr24_-_31257591 0.16 ENSDART00000158808
cnn3a
calponin 3, acidic a
chr14_+_14541725 0.16 ENSDART00000169932
ccdc142
coiled-coil domain containing 142
chr18_-_5822255 0.15 ENSDART00000121503
cplx3b
complexin 3b
chr16_+_14820248 0.15

chr18_+_10815958 0.15 ENSDART00000028938
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr20_+_16822321 0.14 ENSDART00000161226
psmc1b
proteasome 26S subunit, ATPase 1b
chr18_+_7680416 0.14 ENSDART00000132369
rabl2
RAB, member of RAS oncogene family-like 2
chr14_+_7585570 0.12 ENSDART00000161307
ube2d2
ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
chr10_-_33212897 0.11 ENSDART00000081170
cux1a
cut-like homeobox 1a
chr23_-_28368224 0.11 ENSDART00000139537
znf385a
zinc finger protein 385A
chr3_+_24957053 0.10 ENSDART00000138578
st13
ST13, Hsp70 interacting protein
chr7_+_21365735 0.10 ENSDART00000173557
kdm6ba
lysine (K)-specific demethylase 6B, a
chr24_+_3447129 0.10 ENSDART00000134598
wdr37
WD repeat domain 37
chr7_-_49322116 0.09 ENSDART00000174161
brsk2b
BR serine/threonine kinase 2b
chr3_+_21539370 0.08 ENSDART00000156527
crhr1
corticotropin releasing hormone receptor 1
chr17_-_49910160 0.07 ENSDART00000122747
tmem30aa
transmembrane protein 30Aa
chr16_-_52090856 0.06 ENSDART00000155308
FO704712.1
ENSDARG00000063300
chr11_-_3841149 0.05 ENSDART00000082425
gata2a
GATA binding protein 2a
chr6_-_17699766 0.05 ENSDART00000170597
rptor
regulatory associated protein of MTOR, complex 1
chr5_-_27394386 0.04 ENSDART00000171611
ppp3cca
protein phosphatase 3, catalytic subunit, gamma isozyme, a
chr7_-_66641207 0.03

chr23_+_2193828 0.03 ENSDART00000106336
cpeb2
cytoplasmic polyadenylation element binding protein 2
chr7_-_50244264 0.03 ENSDART00000073910
adamtsl5
ADAMTS like 5
chr1_-_37452112 0.02 ENSDART00000142811
hmgb2a
high mobility group box 2a
chr23_-_24468290 0.02 ENSDART00000044918
epha2b
eph receptor A2 b
chr6_-_13215294 0.02 ENSDART00000112883
fmnl2b
formin-like 2b
KN150196v1_+_15294 0.01

chr5_-_68408171 0.01 ENSDART00000109761
ENSDART00000156681
ENSDART00000167680
ENSDARG00000076888
ENSDARG00000076888

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.1 GO:0045933 regulation of skeletal muscle contraction(GO:0014819) positive regulation of muscle contraction(GO:0045933)
1.4 4.2 GO:0045887 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887) positive regulation of neuromuscular junction development(GO:1904398)
1.0 3.1 GO:1902855 nonmotile primary cilium assembly(GO:0035058) regulation of nonmotile primary cilium assembly(GO:1902855)
1.0 2.9 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.6 1.8 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
0.6 3.5 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.5 2.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.4 1.3 GO:1902893 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.3 1.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.3 1.4 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.3 2.8 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.2 1.9 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.2 3.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 2.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.2 0.6 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2 1.9 GO:0051256 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.2 1.2 GO:0071451 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.2 1.1 GO:0006833 water transport(GO:0006833)
0.2 0.6 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 1.6 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.8 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.1 0.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.3 GO:0061011 hepatic duct development(GO:0061011)
0.1 0.8 GO:0042694 muscle cell fate specification(GO:0042694)
0.1 0.7 GO:0006007 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 1.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 1.1 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 2.6 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 1.1 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.1 2.6 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 1.7 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 1.2 GO:0030042 actin filament depolymerization(GO:0030042)
0.1 0.8 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 2.1 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.7 GO:1902686 positive regulation of mitochondrial membrane permeability(GO:0035794) mitochondrial outer membrane permeabilization(GO:0097345) positive regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902110) mitochondrial outer membrane permeabilization involved in programmed cell death(GO:1902686)
0.1 0.5 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.5 GO:0021634 optic nerve formation(GO:0021634)
0.1 2.3 GO:0001707 mesoderm formation(GO:0001707)
0.1 1.1 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 1.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.2 GO:0044209 AMP salvage(GO:0044209)
0.0 3.0 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 0.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 2.7 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 1.1 GO:0006865 amino acid transport(GO:0006865)
0.0 1.1 GO:0001708 cell fate specification(GO:0001708)
0.0 3.6 GO:0007411 axon guidance(GO:0007411)
0.0 1.5 GO:0045087 innate immune response(GO:0045087)
0.0 0.2 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.8 GO:0007030 Golgi organization(GO:0007030)
0.0 0.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0060415 cardiac muscle tissue morphogenesis(GO:0055008) muscle tissue morphogenesis(GO:0060415)
0.0 1.1 GO:0009416 response to light stimulus(GO:0009416)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 10.9 GO:0031672 A band(GO:0031672)
0.3 2.0 GO:0044295 axonal growth cone(GO:0044295)
0.2 1.4 GO:0016234 inclusion body(GO:0016234)
0.2 3.0 GO:0045180 basal cortex(GO:0045180)
0.1 1.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.7 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 2.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 1.1 GO:0071564 npBAF complex(GO:0071564)
0.1 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 2.9 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 2.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.6 GO:0014069 postsynaptic density(GO:0014069)
0.0 3.1 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.5 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.9 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.0 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.5 GO:0031941 filamentous actin(GO:0031941)
0.0 2.7 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.2 GO:0043195 terminal bouton(GO:0043195)
0.0 1.1 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.6 GO:0005871 kinesin complex(GO:0005871)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 9.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.5 2.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.3 1.9 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.3 1.4 GO:0034632 retinol transporter activity(GO:0034632)
0.2 1.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 1.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 2.9 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 1.1 GO:0015250 water channel activity(GO:0015250)
0.1 2.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.9 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.7 GO:0070095 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.1 0.7 GO:0043495 protein anchor(GO:0043495)
0.1 1.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.8 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.2 GO:0004001 adenosine kinase activity(GO:0004001)
0.1 0.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 1.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.2 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 2.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.2 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 1.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 4.8 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 1.1 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 0.5 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 1.1 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 2.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 3.5 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.6 GO:0003777 microtubule motor activity(GO:0003777)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 2.2 NABA COLLAGENS Genes encoding collagen proteins
0.1 1.9 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 2.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 9.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 2.1 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 3.6 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.1 1.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 2.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 2.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases