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Results for patz1
Z-value: 2.58
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Transcription factors associated with patz1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| patz1 | dr10_dc_chr6_+_40954138_40954195 | -0.43 | 9.6e-02 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of patz1
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr13_+_11913290 Show fit | 8.93 |
ENSDART00000079398
|
guanine nucleotide binding protein (G protein), gamma 2 |
|
| chr3_+_28450576 Show fit | 7.43 |
ENSDART00000150893
|
septin 12 |
|
| chr16_-_24220413 Show fit | 6.93 |
ENSDART00000103176
|
basal cell adhesion molecule (Lutheran blood group) |
|
| chr2_+_11973282 Show fit | 6.71 |
ENSDART00000057268
|
growth regulation by estrogen in breast cancer-like |
|
| chr8_+_20125687 Show fit | 6.62 |
ENSDART00000124809
|
acyl-CoA synthetase bubblegum family member 2 |
|
| chr12_-_26760324 Show fit | 6.60 |
ENSDART00000047724
|
zinc finger E-box binding homeobox 1b |
|
| chr23_+_10412852 Show fit | 6.56 |
ENSDART00000142595
|
keratin 18 |
|
| chr16_+_17705704 Show fit | 6.18 |
|
|
|
| chr7_+_21455138 Show fit | 6.18 |
ENSDART00000173992
|
lysine (K)-specific demethylase 6B, a |
|
| chr7_+_34417030 Show fit | 5.98 |
ENSDART00000108473
|
pleckstrin homology domain containing, family G (with RhoGef domain) member 4 |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 14.7 | GO:0048010 | vascular endothelial growth factor receptor signaling pathway(GO:0048010) |
| 0.2 | 8.2 | GO:0018107 | peptidyl-threonine phosphorylation(GO:0018107) |
| 1.0 | 7.7 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
| 0.2 | 7.0 | GO:0007050 | cell cycle arrest(GO:0007050) |
| 1.3 | 6.7 | GO:0045582 | positive regulation of T cell differentiation(GO:0045582) |
| 0.8 | 6.7 | GO:0001957 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 2.2 | 6.6 | GO:0070587 | regulation of cell-cell adhesion involved in gastrulation(GO:0070587) |
| 0.6 | 6.6 | GO:0071425 | hematopoietic stem cell proliferation(GO:0071425) |
| 0.6 | 6.6 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
| 0.0 | 6.0 | GO:0000122 | negative regulation of transcription from RNA polymerase II promoter(GO:0000122) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 19.2 | GO:0005615 | extracellular space(GO:0005615) |
| 0.0 | 17.8 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 1.3 | 14.4 | GO:0031680 | G-protein beta/gamma-subunit complex(GO:0031680) |
| 0.1 | 11.1 | GO:0043235 | receptor complex(GO:0043235) |
| 0.1 | 8.5 | GO:0005814 | centriole(GO:0005814) |
| 0.3 | 8.0 | GO:0031105 | septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156) |
| 0.1 | 6.9 | GO:0042641 | actomyosin(GO:0042641) |
| 0.0 | 6.5 | GO:0045202 | synapse(GO:0045202) |
| 0.4 | 6.2 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 1.2 | 5.8 | GO:0098890 | extrinsic component of postsynaptic membrane(GO:0098890) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 14.4 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.0 | 13.4 | GO:0003779 | actin binding(GO:0003779) |
| 0.0 | 11.0 | GO:0046983 | protein dimerization activity(GO:0046983) |
| 0.1 | 10.8 | GO:0098531 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
| 0.8 | 10.5 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.2 | 9.6 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.4 | 9.1 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 1.0 | 7.7 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 0.1 | 7.2 | GO:0042802 | identical protein binding(GO:0042802) |
| 0.7 | 6.6 | GO:0016405 | CoA-ligase activity(GO:0016405) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 12.6 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.6 | 6.7 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.4 | 6.2 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.2 | 6.0 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 5.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.2 | 5.4 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.2 | 5.0 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.1 | 4.8 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.3 | 4.1 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.5 | 3.4 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 14.4 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.3 | 8.5 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.4 | 7.1 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.2 | 6.7 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.1 | 5.7 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.5 | 5.5 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.3 | 3.9 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.4 | 3.6 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.2 | 3.4 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.1 | 2.9 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |