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Results for patz1

Z-value: 2.58

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Transcription factors associated with patz1

Gene Symbol Gene ID Gene Info
patz1
ENSDARG00000076584 POZ/BTB and AT hook containing zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
patz1dr10_dc_chr6_+_40954138_40954195-0.439.6e-02Click!

Activity profile of patz1 motif

Sorted Z-values of patz1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of patz1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr13_+_11913290 8.93 ENSDART00000079398
gng2
guanine nucleotide binding protein (G protein), gamma 2
chr3_+_28450576 7.43 ENSDART00000150893
sept12
septin 12
chr16_-_24220413 6.93 ENSDART00000103176
bcam
basal cell adhesion molecule (Lutheran blood group)
chr2_+_11973282 6.71 ENSDART00000057268
greb1l
growth regulation by estrogen in breast cancer-like
chr8_+_20125687 6.62 ENSDART00000124809
acsbg2
acyl-CoA synthetase bubblegum family member 2
chr12_-_26760324 6.60 ENSDART00000047724
zeb1b
zinc finger E-box binding homeobox 1b
chr23_+_10412852 6.56 ENSDART00000142595
krt18
keratin 18
chr16_+_17705704 6.18

chr7_+_21455138 6.18 ENSDART00000173992
kdm6ba
lysine (K)-specific demethylase 6B, a
chr7_+_34417030 5.98 ENSDART00000108473
plekhg4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr6_+_47425082 5.97 ENSDART00000171087
si:ch211-286o17.1
si:ch211-286o17.1
chr15_-_11257445 5.82

chr5_+_36487425 5.69 ENSDART00000049900
tagln2
transgelin 2
chr20_-_25063937 5.44 ENSDART00000159122
epha7
eph receptor A7
chr16_-_42486580 5.29 ENSDART00000148475
cspg5a
chondroitin sulfate proteoglycan 5a
chr19_+_12066023 5.28 ENSDART00000130537
spag1a
sperm associated antigen 1a
chr22_+_26543146 5.13

chr14_-_943860 5.02 ENSDART00000010773
acsl1b
acyl-CoA synthetase long-chain family member 1b
chr1_-_674449 5.01 ENSDART00000160564
cyyr1
cysteine/tyrosine-rich 1
chr4_-_25075693 4.99 ENSDART00000025153
gata3
GATA binding protein 3
chr6_+_7092350 4.99 ENSDART00000049695
ENSDART00000136088
ENSDART00000083424
ENSDART00000125912
dzip1
DAZ interacting zinc finger protein 1
chr19_-_5338129 4.92 ENSDART00000081951
stx1b
syntaxin 1B
chr7_-_23965038 4.75 ENSDART00000010124
slc7a8a
solute carrier family 7 (amino acid transporter light chain, L system), member 8a
chr5_-_39910235 4.72 ENSDART00000146237
ENSDART00000163302
fsta
follistatin a
chr8_+_7301525 4.65 ENSDART00000092347
ssuh2rs1
ssu-2 homolog, related sequence 1
chr23_-_2573949 4.61 ENSDART00000123322
snai1b
snail family zinc finger 1b
chr23_-_24468191 4.54 ENSDART00000044918
epha2b
eph receptor A2 b
chr12_+_34631232 4.53 ENSDART00000169634
si:dkey-21c1.8
si:dkey-21c1.8
chr9_+_3458086 4.32 ENSDART00000160977
ENSDART00000114168
CU469503.1
itga6a
ENSDARG00000099348
integrin, alpha 6a
chr2_+_26523457 4.32 ENSDART00000024662
plppr3a
phospholipid phosphatase related 3a
chr14_-_46651359 4.30 ENSDART00000163316
CR383676.1
ENSDARG00000099970
chr14_-_40454194 4.28 ENSDART00000166621
ef1
E74-like factor 1 (ets domain transcription factor)
chr15_-_21901138 4.26 ENSDART00000089953
sik2b
salt-inducible kinase 2b
chr6_+_55022668 4.25 ENSDART00000158845
mybphb
myosin binding protein Hb
chr20_-_21773202 4.24 ENSDART00000133286
si:ch211-207i1.2
si:ch211-207i1.2
chr5_-_36647498 4.22 ENSDART00000112312
lrch2
leucine-rich repeats and calponin homology (CH) domain containing 2
chr23_-_29138952 4.21 ENSDART00000002812
casz1
castor zinc finger 1
chr16_-_46799406 4.18 ENSDART00000115244
MEX3A
mex-3 RNA binding family member A
chr5_-_43896815 4.09 ENSDART00000110076
gas1a
growth arrest-specific 1a
chr3_-_6078015 4.09 ENSDART00000165715
BX284638.1
ENSDARG00000098850
chr9_-_48098629 4.06

chr8_+_10267246 4.06 ENSDART00000159312
ENSDART00000160766
pim1
Pim-1 proto-oncogene, serine/threonine kinase
chr18_-_11216447 4.04 ENSDART00000040500
tspan9a
tetraspanin 9a
chr12_+_34631310 4.01 ENSDART00000169634
si:dkey-21c1.8
si:dkey-21c1.8
chr15_+_19902697 3.96 ENSDART00000101204
alcamb
activated leukocyte cell adhesion molecule b
chr20_-_158899 3.91 ENSDART00000131635
slc16a10
solute carrier family 16 (aromatic amino acid transporter), member 10
chr6_+_39373026 3.83 ENSDART00000157165
si:dkey-195m11.8
si:dkey-195m11.8
chr13_-_34667689 3.80 ENSDART00000025719
ism1
isthmin 1
chr13_+_11912981 3.66 ENSDART00000158244
gng2
guanine nucleotide binding protein (G protein), gamma 2
chr11_-_25693072 3.62 ENSDART00000122011
kaznb
kazrin, periplakin interacting protein b
chr21_+_5483017 3.60 ENSDART00000160885
stbd1
starch binding domain 1
chr7_+_73408688 3.58 ENSDART00000159745
PCP4L1
Purkinje cell protein 4 like 1
chr12_+_31501522 3.58 ENSDART00000144422
cpn1
carboxypeptidase N, polypeptide 1
chr24_+_5205878 3.58 ENSDART00000106488
ENSDART00000005901
plod2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr5_+_6054781 3.55 ENSDART00000060532
zgc:110796
zgc:110796
chr17_+_8166167 3.49 ENSDART00000169900
cdc42bpaa
CDC42 binding protein kinase alpha (DMPK-like) a
chr3_+_12401750 3.48 ENSDART00000167177
ccnf
cyclin F
chr13_+_22173410 3.46 ENSDART00000173405
usp54a
ubiquitin specific peptidase 54a
chr9_-_44493074 3.43 ENSDART00000167685
neurod1
neuronal differentiation 1
chr24_+_9335428 3.41 ENSDART00000132688
si:ch211-285f17.1
si:ch211-285f17.1
chr15_-_40328793 3.39 ENSDART00000155018
si:ch211-281l24.3
si:ch211-281l24.3
chr15_-_4154407 3.39 ENSDART00000090624
lpar6a
lysophosphatidic acid receptor 6a
chr7_-_52283383 3.39 ENSDART00000165649
tcf12
transcription factor 12
chr8_+_1122000 3.39 ENSDART00000127252
slc35d2
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr19_-_24971633 3.39 ENSDART00000162801
polr3gla
polymerase (RNA) III (DNA directed) polypeptide G like a
chr22_+_33177432 3.38 ENSDART00000126885
dag1
dystroglycan 1
chr10_+_10830549 3.34 ENSDART00000101077
ENSDART00000139143
ptgdsa
prostaglandin D2 synthase a
chr23_-_7283514 3.25 ENSDART00000156369
CR589876.1
ENSDARG00000096997
chr5_-_36237656 3.24 ENSDART00000032481
ckma
creatine kinase, muscle a
chr6_+_2849460 3.23

chr8_+_25748377 3.22 ENSDART00000062406
cacna1sb
calcium channel, voltage-dependent, L type, alpha 1S subunit, b
chr10_-_42032702 3.19

chr15_+_46114986 3.19 ENSDART00000156366
si:ch1073-340i21.3
si:ch1073-340i21.3
chr19_-_39048324 3.17 ENSDART00000086717
col16a1
collagen, type XVI, alpha 1
chr16_+_5625301 3.15

chr15_-_17074348 3.15 ENSDART00000156768
hip1
huntingtin interacting protein 1
chr14_+_33117964 3.14 ENSDART00000075278
atp1b4
ATPase, Na+/K+ transporting, beta 4 polypeptide
chr25_-_325847 3.14 ENSDART00000059514
prickle1a
prickle homolog 1a
chr5_+_68410884 3.12 ENSDART00000153691
CU928129.1
ENSDARG00000097815
chr8_-_14142049 3.10 ENSDART00000126432
rhoaa
ras homolog gene family, member Aa
chr5_-_25866099 3.09 ENSDART00000144035
arvcfb
armadillo repeat gene deleted in velocardiofacial syndrome b
chr13_-_36996246 3.07 ENSDART00000133242
syne2b
spectrin repeat containing, nuclear envelope 2b
chr19_+_7234029 3.05 ENSDART00000080348
brd2a
bromodomain containing 2a
chr1_-_50831155 3.02 ENSDART00000152719
spred2a
sprouty-related, EVH1 domain containing 2a
chr8_-_52952226 3.02 ENSDART00000168185
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr13_+_28601627 3.00 ENSDART00000015773
ldb1a
LIM domain binding 1a
chr25_-_340711 2.99 ENSDART00000178866
CU929174.1
ENSDARG00000107546
chr11_+_18817797 2.94

chr5_+_45822196 2.92

chr5_-_43896757 2.90 ENSDART00000110076
gas1a
growth arrest-specific 1a
chr8_+_29953399 2.89 ENSDART00000149372
ENSDART00000007640
ptch1
ptch1
patched 1
patched 1
chr19_-_6384776 2.89

chr5_+_66712197 2.88 ENSDART00000014822
ebf2
early B-cell factor 2
chr1_-_11591843 2.88 ENSDART00000003825
cplx2l
complexin 2, like
chr16_+_29277783 2.84 ENSDART00000149569
CR848047.1
ENSDARG00000095906
chr25_+_34270560 2.84 ENSDART00000146669
wwp2
WW domain containing E3 ubiquitin protein ligase 2
chr13_-_34667430 2.84 ENSDART00000025719
ism1
isthmin 1
chr7_-_57796486 2.81 ENSDART00000043984
ank2b
ankyrin 2b, neuronal
chr18_+_44656323 2.76 ENSDART00000059063
ehd2b
EH-domain containing 2b
chr1_-_51862897 2.76 ENSDART00000136469
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr9_-_24431684 2.73 ENSDART00000039399
cavin2a
caveolae associated protein 2a
chr23_+_25782195 2.73 ENSDART00000060059
rbms2b
RNA binding motif, single stranded interacting protein 2b
chr5_-_31275147 2.73 ENSDART00000098160
tmem119b
transmembrane protein 119b
chr19_-_46396376 2.69

chr13_+_22350043 2.68 ENSDART00000136863
ldb3a
LIM domain binding 3a
chr5_-_31301280 2.66 ENSDART00000141446
coro1cb
coronin, actin binding protein, 1Cb
chr15_-_17074107 2.66 ENSDART00000156768
hip1
huntingtin interacting protein 1
chr11_+_37345024 2.66 ENSDART00000077496
hp1bp3
heterochromatin protein 1, binding protein 3
chr2_+_3864843 2.65 ENSDART00000108964
ENSDART00000128514
egfra
epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
chr2_-_23348612 2.64 ENSDART00000110373
znf414
zinc finger protein 414
chr13_-_14978365 2.59

chr3_+_52901602 2.59 ENSDART00000114343
brd4
bromodomain containing 4
chr2_+_21342233 2.58 ENSDART00000062563
rreb1b
ras responsive element binding protein 1b
chr12_-_36138709 2.58 ENSDART00000130985
st6galnac
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase
chr8_-_53508979 2.58 ENSDART00000158789
chdh
choline dehydrogenase
chr14_-_6901415 2.57 ENSDART00000167994
ENSDART00000166532
stox2b
storkhead box 2b
chr20_-_40422997 2.57 ENSDART00000075112
clvs2
clavesin 2
chr2_-_44429891 2.56 ENSDART00000163040
ENSDART00000056372
ENSDART00000109251
ENSDART00000166923
ENSDART00000132682
mpz
myelin protein zero
chr19_-_5142310 2.56 ENSDART00000130062
chd4a
chromodomain helicase DNA binding protein 4a
chr19_-_9603597 2.53 ENSDART00000045245
ing4
inhibitor of growth family, member 4
chr15_-_33669717 2.53 ENSDART00000161151
stard13b
StAR-related lipid transfer (START) domain containing 13b
chr4_+_13453879 2.50 ENSDART00000145069
dyrk2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr24_-_21114505 2.49 ENSDART00000111025
boc
BOC cell adhesion associated, oncogene regulated
chr9_-_22140954 2.47 ENSDART00000146528
lmo7a
LIM domain 7a
chr22_-_22694468 2.46 ENSDART00000166794
nr5a2
nuclear receptor subfamily 5, group A, member 2
chr5_+_23585492 2.44 ENSDART00000135083
tp53
tumor protein p53
chr9_-_33916709 2.43 ENSDART00000028225
mao
monoamine oxidase
chr1_+_54231447 2.39 ENSDART00000145652
golga7ba
golgin A7 family, member Ba
chr3_-_32190009 2.38

chr11_+_23695123 2.37 ENSDART00000000486
cntn2
contactin 2
chr11_+_23522743 2.36 ENSDART00000121874
nfasca
neurofascin homolog (chicken) a
chr21_+_28408329 2.36 ENSDART00000077871
pygma
phosphorylase, glycogen, muscle A
chr22_+_24131239 2.35 ENSDART00000159165
b3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr9_-_24602136 2.34 ENSDART00000135897
tmeff2a
transmembrane protein with EGF-like and two follistatin-like domains 2a
chr14_-_9216303 2.32 ENSDART00000054689
atoh8
atonal bHLH transcription factor 8
chr8_-_30233470 2.31 ENSDART00000139864
zgc:162939
zgc:162939
chr5_-_9497591 2.29 ENSDART00000113448
ENSDARG00000073808
ENSDARG00000073808
chr8_+_25235278 2.29 ENSDART00000143554
ampd2b
adenosine monophosphate deaminase 2b
chr4_-_16417703 2.28 ENSDART00000013085
dcn
decorin
chr16_+_17706003 2.28

chr11_-_29586549 2.27 ENSDART00000079149
xk
X-linked Kx blood group (McLeod syndrome)
chr1_-_37990863 2.26 ENSDART00000132402
gpm6ab
glycoprotein M6Ab
chr15_-_1225595 2.26

chr24_+_38783264 2.26 ENSDART00000154214
si:ch73-70c5.1
si:ch73-70c5.1
KN149874v1_+_3991 2.25

chr23_-_18945009 2.25 ENSDART00000080064
CR847953.1
ENSDARG00000057403
chr24_+_35500964 2.23 ENSDART00000058571
snai2
snail family zinc finger 2
chr16_+_42993841 2.21 ENSDART00000156767
CR854827.4
ENSDARG00000097750
chr9_+_56881036 2.19

chr7_+_37105282 2.18

chr24_+_9335316 2.17 ENSDART00000132688
si:ch211-285f17.1
si:ch211-285f17.1
chr11_-_40415291 2.16

chr17_+_27383737 2.13 ENSDART00000156756
FP017274.1
ENSDARG00000097369
chr2_+_43619752 2.12 ENSDART00000142078
ENSDART00000098265
ENSDART00000098267
nrp1b
neuropilin 1b
chr25_+_4909062 2.12 ENSDART00000170049
parvb
parvin, beta
chr21_+_13764828 2.11 ENSDART00000171306
stxbp1a
syntaxin binding protein 1a
chr16_+_5625552 2.09

chr10_+_43360137 2.07 ENSDART00000012522
vcanb
versican b
chr2_-_44330405 2.06 ENSDART00000111246
cadm3
cell adhesion molecule 3
chr23_+_6298911 2.06 ENSDART00000139795
syt2a
synaptotagmin IIa
chr16_+_11138924 2.06 ENSDART00000091183
erfl3
Ets2 repressor factor like 3
chr13_-_7897936 2.06 ENSDART00000139728
si:ch211-250c4.4
si:ch211-250c4.4
chr13_+_4276783 2.05 ENSDART00000148280
prr18
proline rich 18
chr18_-_45750 2.05 ENSDART00000148821
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr21_-_11554253 2.05 ENSDART00000133443
cast
calpastatin
chr22_-_95158 2.01

chr1_-_11591684 2.00 ENSDART00000003825
cplx2l
complexin 2, like
chr14_+_1093068 1.96 ENSDART00000162660
si:ch1073-303k11.2
si:ch1073-303k11.2
chr16_-_20901879 1.95 ENSDART00000103630
creb5b
cAMP responsive element binding protein 5b
chr10_+_22759607 1.95

chr20_+_545574 1.94 ENSDART00000152453
dse
dermatan sulfate epimerase
chr15_+_42440802 1.91 ENSDART00000089694
tiam1b
T-cell lymphoma invasion and metastasis 1b
chr18_-_41660821 1.90 ENSDART00000024087
fzd9b
frizzled class receptor 9b
chr22_-_17652938 1.89 ENSDART00000139911
tjp3
tight junction protein 3
chr18_+_14627030 1.88 ENSDART00000080788
wfdc1
WAP four-disulfide core domain 1
chr16_+_11138879 1.87 ENSDART00000091183
erfl3
Ets2 repressor factor like 3
chr20_+_37940880 1.87 ENSDART00000165887
flvcr1
feline leukemia virus subgroup C cellular receptor 1
chr19_+_4996328 1.85 ENSDART00000165082
ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr21_+_26660833 1.84 ENSDART00000004109
gng3
guanine nucleotide binding protein (G protein), gamma 3
chr14_+_23986703 1.83 ENSDART00000079164
klhl3
kelch-like family member 3
chr10_+_31358236 1.80 ENSDART00000145562
robo4
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr19_-_39048402 1.80 ENSDART00000086717
col16a1
collagen, type XVI, alpha 1
chr7_-_56493164 1.79

chr20_+_20772543 1.79 ENSDART00000152481
rtn1b
reticulon 1b
chr10_-_21096635 1.78 ENSDART00000091004
pcdh1a
protocadherin 1a
chr5_-_31275259 1.77 ENSDART00000098160
tmem119b
transmembrane protein 119b
chr5_+_36014029 1.77 ENSDART00000150574
nova1
neuro-oncological ventral antigen 1
chr23_+_22408855 1.76 ENSDART00000147696
rap1gap
RAP1 GTPase activating protein
chr16_-_21981065 1.75 ENSDART00000078858
si:ch73-86n18.1
si:ch73-86n18.1
chr8_+_8763233 1.75

chr11_-_80746 1.75

chr2_+_47885551 1.73

chr9_-_46272322 1.72 ENSDART00000169682
hdac4
histone deacetylase 4
KN149874v1_+_3898 1.71

chr15_+_42440952 1.70 ENSDART00000089694
tiam1b
T-cell lymphoma invasion and metastasis 1b
chr4_-_25075558 1.69 ENSDART00000025153
gata3
GATA binding protein 3
chr23_-_624534 1.68 ENSDART00000132175
nadl1.1
neural adhesion molecule L1.1
chr4_+_149696 1.68 ENSDART00000161055
dusp16
dual specificity phosphatase 16
chr13_-_17729411 1.67 ENSDART00000054579
march8
membrane-associated ring finger (C3HC4) 8
chr5_+_63726719 1.67 ENSDART00000173886
si:ch1073-363c19.3
si:ch1073-363c19.3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.6 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
1.8 5.3 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
1.6 4.9 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
1.5 4.5 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
1.3 6.7 GO:0045582 positive regulation of T cell differentiation(GO:0045582)
1.2 3.6 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
1.0 7.7 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.9 3.6 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.9 3.6 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.8 6.7 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.8 3.0 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.7 2.0 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.7 4.7 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.7 2.0 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.6 1.9 GO:0097037 heme export(GO:0097037)
0.6 3.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.6 6.6 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.6 6.6 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.6 2.9 GO:0036371 protein localization to T-tubule(GO:0036371)
0.6 2.3 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.6 3.5 GO:0046606 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.6 4.0 GO:0021885 forebrain cell migration(GO:0021885)
0.5 1.5 GO:0055004 atrial cardiac myofibril assembly(GO:0055004)
0.5 4.4 GO:0032264 IMP salvage(GO:0032264)
0.5 3.4 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.5 0.5 GO:0070640 vitamin D3 metabolic process(GO:0070640)
0.5 14.7 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.4 5.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.4 3.2 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.4 1.6 GO:0044209 AMP salvage(GO:0044209)
0.4 5.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.4 1.9 GO:0030104 water homeostasis(GO:0030104)
0.4 2.6 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.3 1.0 GO:0031639 plasminogen activation(GO:0031639)
0.3 2.4 GO:0042135 catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712) neurotransmitter catabolic process(GO:0042135)
0.3 1.4 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.3 3.4 GO:0007525 somatic muscle development(GO:0007525) T-tubule organization(GO:0033292)
0.3 5.8 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.3 1.8 GO:0070293 renal absorption(GO:0070293)
0.3 1.1 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.3 5.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.3 3.7 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.3 4.0 GO:0060975 cardioblast migration(GO:0003260) cardioblast migration to the midline involved in heart field formation(GO:0060975)
0.3 3.1 GO:0021535 cell migration in hindbrain(GO:0021535)
0.3 2.8 GO:0060021 palate development(GO:0060021)
0.3 4.6 GO:0042476 odontogenesis(GO:0042476)
0.3 3.9 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.2 1.0 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.2 2.4 GO:0019226 transmission of nerve impulse(GO:0019226)
0.2 5.4 GO:0015804 neutral amino acid transport(GO:0015804)
0.2 4.2 GO:0050654 chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.2 4.0 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.2 1.4 GO:0043525 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.2 2.0 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.2 1.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 0.7 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.2 5.4 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.2 3.4 GO:0050679 positive regulation of epithelial cell proliferation(GO:0050679)
0.2 1.3 GO:0048796 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.2 3.3 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.2 0.6 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.2 2.4 GO:0009251 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.2 2.3 GO:0070831 basement membrane assembly(GO:0070831)
0.2 4.1 GO:0007634 optokinetic behavior(GO:0007634)
0.2 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 4.7 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.2 3.1 GO:0002574 thrombocyte differentiation(GO:0002574)
0.2 5.0 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.2 8.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.2 7.0 GO:0007050 cell cycle arrest(GO:0007050)
0.2 3.6 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.2 0.6 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.2 2.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 1.5 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 1.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.6 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 0.4 GO:0010586 miRNA metabolic process(GO:0010586)
0.1 1.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 1.1 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.1 2.0 GO:0060729 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.1 1.8 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.5 GO:0090594 inflammatory response to wounding(GO:0090594)
0.1 3.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 1.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 2.4 GO:0097581 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.1 3.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.8 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.1 3.7 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.1 2.3 GO:0001558 regulation of cell growth(GO:0001558)
0.1 0.8 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 1.4 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 0.8 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.1 1.1 GO:0030316 osteoclast differentiation(GO:0030316)
0.1 0.4 GO:1903288 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 4.3 GO:0009755 hormone-mediated signaling pathway(GO:0009755)
0.1 0.4 GO:1901998 toxin transport(GO:1901998)
0.1 2.9 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 1.2 GO:0001649 osteoblast differentiation(GO:0001649)
0.1 0.5 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 0.2 GO:1904358 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.1 0.4 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 3.5 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.1 0.9 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1 3.9 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 2.8 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.8 GO:0097178 ruffle organization(GO:0031529) ruffle assembly(GO:0097178)
0.1 3.2 GO:0070509 calcium ion import(GO:0070509)
0.1 0.9 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 1.2 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.1 0.6 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 1.2 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.1 0.8 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.1 4.2 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.1 0.2 GO:0006407 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
0.1 1.1 GO:0048883 neuromast primordium migration(GO:0048883) posterior lateral line neuromast primordium migration(GO:0048920)
0.0 5.0 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 3.5 GO:0030155 regulation of cell adhesion(GO:0030155)
0.0 1.9 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 1.5 GO:0001570 vasculogenesis(GO:0001570)
0.0 0.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 2.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.8 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.7 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 0.5 GO:0051289 protein homotetramerization(GO:0051289)
0.0 3.5 GO:0016579 protein deubiquitination(GO:0016579)
0.0 1.6 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.9 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 2.7 GO:0007626 locomotory behavior(GO:0007626)
0.0 6.0 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.9 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 2.0 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.7 GO:0048916 posterior lateral line development(GO:0048916)
0.0 4.2 GO:0045664 regulation of neuron differentiation(GO:0045664)
0.0 3.4 GO:0007411 axon guidance(GO:0007411)
0.0 2.1 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 2.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.6 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 1.2 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.8 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 1.4 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.6 GO:0071599 otic vesicle development(GO:0071599)
0.0 0.5 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.7 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 1.4 GO:0048793 pronephros development(GO:0048793)
0.0 1.1 GO:0016485 protein processing(GO:0016485)
0.0 0.3 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.2 GO:0070654 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.0 0.1 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 1.2 GO:0051169 nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 14.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
1.2 5.8 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.5 3.4 GO:0044295 axonal growth cone(GO:0044295)
0.5 5.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.4 4.9 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.4 3.6 GO:0098533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.4 6.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.4 1.6 GO:0070062 extracellular exosome(GO:0070062)
0.4 1.1 GO:0000798 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.4 5.4 GO:0043195 terminal bouton(GO:0043195)
0.3 8.0 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.3 3.4 GO:0016011 dystroglycan complex(GO:0016011)
0.3 1.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.3 1.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 2.7 GO:0009925 basal plasma membrane(GO:0009925)
0.2 3.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 2.5 GO:0030056 hemidesmosome(GO:0030056)
0.2 2.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.2 2.3 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.2 2.9 GO:0030315 T-tubule(GO:0030315)
0.2 1.5 GO:0005581 collagen trimer(GO:0005581)
0.2 2.4 GO:0043209 myelin sheath(GO:0043209)
0.2 0.8 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 2.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.6 GO:0032019 mitochondrial cloud(GO:0032019)
0.1 1.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 4.3 GO:0008305 integrin complex(GO:0008305)
0.1 0.9 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 8.5 GO:0005814 centriole(GO:0005814)
0.1 1.5 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 6.9 GO:0042641 actomyosin(GO:0042641)
0.1 3.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 2.7 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 1.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 1.0 GO:0005801 cis-Golgi network(GO:0005801)
0.1 4.1 GO:0030027 lamellipodium(GO:0030027)
0.1 11.1 GO:0043235 receptor complex(GO:0043235)
0.1 0.7 GO:0016272 prefoldin complex(GO:0016272)
0.0 1.0 GO:0043025 neuronal cell body(GO:0043025)
0.0 1.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.6 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 2.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 17.8 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 3.4 GO:0000793 condensed chromosome(GO:0000793)
0.0 1.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.8 GO:0030141 secretory granule(GO:0030141)
0.0 19.2 GO:0005615 extracellular space(GO:0005615)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 2.4 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.3 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 3.6 GO:0005912 adherens junction(GO:0005912)
0.0 6.5 GO:0045202 synapse(GO:0045202)
0.0 1.3 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.4 GO:0019867 outer membrane(GO:0019867) organelle outer membrane(GO:0031968)
0.0 5.4 GO:0005576 extracellular region(GO:0005576)
0.0 0.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.8 GO:0016607 nuclear speck(GO:0016607)
0.0 0.5 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 2.3 GO:0005743 mitochondrial inner membrane(GO:0005743)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 14.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
1.0 7.7 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.9 4.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.8 2.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.8 3.9 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.8 10.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.8 3.0 GO:0030274 LIM domain binding(GO:0030274)
0.7 1.5 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.7 2.2 GO:0005463 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.7 2.9 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.7 3.6 GO:2001070 starch binding(GO:2001070)
0.7 2.8 GO:0004046 aminoacylase activity(GO:0004046)
0.7 3.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.7 6.6 GO:0016405 CoA-ligase activity(GO:0016405)
0.5 1.6 GO:0004001 adenosine kinase activity(GO:0004001)
0.5 5.0 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.5 2.4 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.4 4.7 GO:0048185 activin binding(GO:0048185)
0.4 9.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.4 5.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.4 3.2 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.4 3.9 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.4 3.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.4 3.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.3 3.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.3 1.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 3.7 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.2 2.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 3.0 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 2.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 3.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 2.0 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2 2.5 GO:0030506 ankyrin binding(GO:0030506)
0.2 4.4 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.2 2.0 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.2 4.1 GO:0035497 cAMP response element binding(GO:0035497)
0.2 2.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.2 3.4 GO:0043236 laminin binding(GO:0043236)
0.2 2.9 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.2 2.7 GO:0005080 protein kinase C binding(GO:0005080)
0.2 5.4 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.2 0.9 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2 1.9 GO:0015232 heme transporter activity(GO:0015232)
0.2 1.9 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.2 9.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 2.7 GO:0042562 hormone binding(GO:0042562)
0.2 1.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 10.8 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 0.8 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 1.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 2.7 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.8 GO:0060182 apelin receptor activity(GO:0060182)
0.1 1.0 GO:0004180 carboxypeptidase activity(GO:0004180)
0.1 7.2 GO:0042802 identical protein binding(GO:0042802)
0.1 1.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 2.0 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 1.5 GO:0005112 Notch binding(GO:0005112)
0.1 0.5 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 1.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.4 GO:0017081 chloride channel regulator activity(GO:0017081) chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 0.7 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 2.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.5 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 0.8 GO:0016408 C-acyltransferase activity(GO:0016408)
0.1 0.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 3.6 GO:0045296 cadherin binding(GO:0045296)
0.1 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.1 3.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.8 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 5.2 GO:0060090 binding, bridging(GO:0060090)
0.0 1.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 1.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 4.3 GO:0019901 protein kinase binding(GO:0019901)
0.0 3.5 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 13.4 GO:0003779 actin binding(GO:0003779)
0.0 2.6 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 0.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 1.9 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 5.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 11.0 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 2.2 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 2.8 GO:0016874 ligase activity(GO:0016874)
0.0 1.0 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.2 GO:0030165 PDZ domain binding(GO:0030165)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 12.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.6 6.7 PID IL27 PATHWAY IL27-mediated signaling events
0.5 3.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.4 6.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.3 1.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3 4.1 PID IL5 PATHWAY IL5-mediated signaling events
0.3 0.5 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.2 5.0 NABA COLLAGENS Genes encoding collagen proteins
0.2 5.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.2 6.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.2 1.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 1.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 2.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 1.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 1.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 4.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 1.9 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 5.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.2 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 14.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.5 5.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.4 7.1 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.4 3.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.3 2.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.3 3.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 8.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 6.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 1.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 3.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2 1.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 2.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 1.9 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 2.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 5.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.9 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.1 0.6 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 0.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.0 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 1.2 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 1.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins