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Results for pax10+pax4+pax6a+pax6b

Z-value: 0.99

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Transcription factors associated with pax10+pax4+pax6a+pax6b

Gene Symbol Gene ID Gene Info
ENSDARG00000021336 paired box 4
ENSDARG00000045936 paired box 6b
ENSDARG00000053364 paired box 10
ENSDARG00000103379 paired box 6a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pax6bdr10_dc_chr7_+_15619409_15619438-0.611.2e-02Click!
pax6adr10_dc_chr25_-_14949028_14949084-0.581.9e-02Click!

Activity profile of pax10+pax4+pax6a+pax6b motif

Sorted Z-values of pax10+pax4+pax6a+pax6b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of pax10+pax4+pax6a+pax6b

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_+_52456064 2.92 ENSDART00000012758
zgc:77112
chr16_+_39209567 2.55 ENSDART00000121756
syntabulin (syntaxin-interacting)
chr5_+_57254393 2.06 ENSDART00000050949
B-cell translocation gene 4
chr18_+_14308032 2.05

chr17_-_30884905 2.01 ENSDART00000131633
ENSDART00000146824
Enah/Vasp-like a
chr10_-_8088063 1.90 ENSDART00000099031
zgc:136254
chr21_-_2296253 1.85 ENSDART00000162867
zgc:66483
chr10_-_8094671 1.54 ENSDART00000099033
zgc:158494
chr21_-_2350174 1.37 ENSDART00000168946
si:ch211-241b2.4
chr16_-_39209426 1.36

chr25_-_8548041 1.34 ENSDART00000155280
GDP-D-glucose phosphorylase 1
chr9_+_8990576 1.31 ENSDART00000133899
ubiquitin conjugating enzyme E2 A, like
chr19_-_4876806 1.28 ENSDART00000141336
ENSDART00000110551
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr2_+_36110584 1.27 ENSDART00000163189
ENSDARG00000101668
chr12_-_35481361 1.26 ENSDART00000158658
ENSDART00000168958
ENSDART00000162175
SEC24 homolog C, COPII coat complex component
chr4_-_72228164 1.25

chr21_-_3548863 1.24 ENSDART00000086492
ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr18_-_20476969 1.24 ENSDART00000060311
progestin and adipoQ receptor family member Va
chr23_+_17999913 1.23 ENSDART00000012540
chitinase, acidic.4
chr21_-_2350090 1.22 ENSDART00000168946
si:ch211-241b2.4
chr25_-_1243081 1.13 ENSDART00000156062
calmodulin-like 4b
chr22_-_21021942 1.12 ENSDART00000133982
single stranded DNA binding protein 4
chr9_+_8387050 1.09 ENSDART00000136847
si:dkey-90l23.2
chr10_+_19610019 1.07

chr25_+_7358777 0.99 ENSDART00000161593
phosphatidylserine synthase 2
chr3_-_7487722 0.98

chr14_-_14353487 0.97 ENSDART00000172241
NAD(P) dependent steroid dehydrogenase-like
chr14_+_21373857 0.95 ENSDART00000079649
ENSDART00000165795
NADH dehydrogenase (ubiquinone) Fe-S protein 8b
chr25_-_9889107 0.93 ENSDART00000137407
ENSDARG00000093575
chr19_+_43090603 0.91 ENSDART00000018328
F-box and leucine-rich repeat protein 2
chr5_+_47324215 0.89 ENSDART00000097429
ENSDARG00000067658
chr13_-_32595706 0.89 ENSDART00000012232
prenyl (decaprenyl) diphosphate synthase, subunit 2
chr14_+_31189527 0.88 ENSDART00000053026
family with sequence similarity 122B
chr18_-_50439653 0.85 ENSDART00000151038
ENSDARG00000096262
chr13_-_49886891 0.84 ENSDART00000074230
protein kinase containing Z-DNA binding domains
chr7_+_26274744 0.83 ENSDART00000135313
tyrosine kinase, non-receptor, 1
chr14_-_30578373 0.83 ENSDART00000176631
si:ch211-126c2.4
chr1_-_28849479 0.82 ENSDART00000109224
ENSDARG00000074117
chr12_+_23691261 0.82 ENSDART00000066331
supervillin a
chr24_-_36383243 0.82 ENSDART00000155892
si:ch211-40k21.5
chr7_-_30353095 0.81 ENSDART00000173828
ring finger protein 111
chr12_-_13692190 0.80 ENSDART00000152370
forkhead box H1
chr12_-_3042394 0.79 ENSDART00000002867
ENSDART00000126315
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
KN150663v1_-_3381 0.77

chr3_-_54352535 0.77 ENSDART00000021977
ENSDART00000078973
DNA (cytosine-5-)-methyltransferase 1
chr5_-_68751287 0.76 ENSDART00000112692
ENSDARG00000077155
chr10_+_24721086 0.76 ENSDART00000079549
transmembrane phosphatase with tensin homology
chr24_+_28304276 0.76 ENSDART00000018095
SH3-domain GRB2-like endophilin B1a
chr16_-_5205600 0.75 ENSDART00000148955
branched chain keto acid dehydrogenase E1, beta polypeptide
chr9_+_8990774 0.74 ENSDART00000133899
ubiquitin conjugating enzyme E2 A, like
chr20_-_25587274 0.74 ENSDART00000141340
si:dkey-183n20.15
chr19_+_43090664 0.74 ENSDART00000018328
F-box and leucine-rich repeat protein 2
chr5_-_10966029 0.71

chr11_-_11353309 0.70 ENSDART00000016677
zgc:77929
chr22_+_8973724 0.70 ENSDART00000106414
ribonuclease/angiogenin inhibitor 1
chr16_+_39209538 0.69 ENSDART00000121756
syntabulin (syntaxin-interacting)
chr3_-_7487630 0.68

chr16_+_11888601 0.68 ENSDART00000133497
si:dkey-250k15.4
chr21_-_33070005 0.67

chr8_+_25873546 0.67 ENSDART00000137247
transmembrane protein 115
chr22_-_21021984 0.67 ENSDART00000133982
single stranded DNA binding protein 4
chr20_-_48957424 0.66 ENSDART00000158993
ENSDARG00000102751
chr8_+_26064660 0.66 ENSDART00000099283
DALR anticodon binding domain containing 3
chr1_+_51087450 0.66 ENSDART00000040397
peroxiredoxin 2
chr25_+_4508802 0.65 ENSDART00000021120
protein-glucosylgalactosylhydroxylysine glucosidase
chr7_-_45579815 0.65 ENSDART00000170224
SHC SH2-domain binding protein 1
chr15_+_20054306 0.65 ENSDART00000155199
zgc:112083
chr13_-_32595667 0.65 ENSDART00000012232
prenyl (decaprenyl) diphosphate synthase, subunit 2
chr21_-_39132507 0.64 ENSDART00000065143
unc-119 homolog b (C. elegans)
chr7_-_41232765 0.64 ENSDART00000173577
ENSDARG00000105669
chr7_+_26274687 0.64 ENSDART00000135313
tyrosine kinase, non-receptor, 1
chr23_-_27579257 0.63 ENSDART00000137229
ankyrin repeat and SOCS box containing 8
chr7_-_20330881 0.63 ENSDART00000169750
si:dkey-19b23.11
chr20_-_47470364 0.63 ENSDART00000040679
dystrobrevin, beta a
chr19_-_41933808 0.63 ENSDART00000062080
chromatin accessibility complex 1
chr7_-_30353179 0.62 ENSDART00000173828
ring finger protein 111
chr20_-_48957517 0.61 ENSDART00000158993
ENSDARG00000102751
chr8_-_44230474 0.61 ENSDART00000143020
syntaxin 2b
chr13_+_8509859 0.61 ENSDART00000140489
epithelial cell adhesion molecule
chr4_+_11763234 0.60 ENSDART00000153714
ENSDART00000156950
ENSDARG00000096099
chr7_-_8492862 0.60 ENSDART00000172807
ENSDART00000173026
si:ch211-1o7.3
chr19_-_42933592 0.57 ENSDART00000007642
zgc:110239
chr3_-_54352640 0.57 ENSDART00000128041
DNA (cytosine-5-)-methyltransferase 1
chr11_+_42438405 0.57 ENSDART00000163269
zgc:194981
chr8_+_41004169 0.57

chr23_-_27318468 0.57

chr3_-_23382550 0.57 ENSDART00000170200
ENSDARG00000101975
chr19_-_11320648 0.55 ENSDART00000148697
signal sequence receptor, beta
chr19_+_20579471 0.54 ENSDART00000090942
coiled-coil domain containing 126
chr19_-_20578899 0.54 ENSDART00000151646
family with sequence similarity 221, member A
chr8_+_41003546 0.54 ENSDART00000129344
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr6_-_51811024 0.53 ENSDART00000031597
proteasome inhibitor subunit 1
chr5_+_47324353 0.53 ENSDART00000097429
ENSDARG00000067658
chr25_-_8548210 0.53 ENSDART00000155280
GDP-D-glucose phosphorylase 1
chr5_+_31541677 0.53 ENSDART00000041504
tescalcin b
chr19_-_3785774 0.53 ENSDART00000161738
small integral membrane protein 13
chr16_+_11888545 0.52 ENSDART00000133497
si:dkey-250k15.4
chr18_+_36801847 0.52 ENSDART00000004129
si:ch211-160d20.3
chr3_-_54414615 0.52 ENSDART00000053106
sphingosine-1-phosphate receptor 2
chr12_+_23691397 0.52 ENSDART00000066331
supervillin a
chr1_+_45148002 0.52 ENSDART00000148086
mitogen-activated protein kinase kinase 7
chr5_-_45986774 0.51

chr23_-_18454945 0.50 ENSDART00000016891
hydroxysteroid (17-beta) dehydrogenase 10
chr15_-_743589 0.50 ENSDART00000156200
zgc:174574
chr22_+_22413803 0.49 ENSDART00000147825
kinesin family member 14
chr25_+_19772873 0.48 ENSDART00000170493
GRAM domain containing 4b
chr13_+_50167246 0.47 ENSDART00000178572
ENSDARG00000108623
chr23_-_16160099 0.47 ENSDART00000042469
ENSDART00000146605
MRG/MORF4L binding protein
chr7_-_3986977 0.47

KN150101v1_-_19017 0.47

chr19_-_11097075 0.47 ENSDART00000010997
tropomyosin 3
chr24_-_26334771 0.47 ENSDART00000079984
ENSDART00000136871
ribosomal protein L22-like 1
chr21_-_39521698 0.46 ENSDART00000020174
dynein, light chain, LC8-type 2b
chr12_+_20685139 0.46 ENSDART00000153261
ENSDARG00000096799
chr5_-_23763146 0.46

chr9_+_9956221 0.46 ENSDART00000168559
transcription termination factor, RNA polymerase II
chr11_+_19440815 0.46 ENSDART00000005639
THO complex 7
chr5_+_25612385 0.46 ENSDART00000098514
occludin b
chr21_-_39132951 0.46 ENSDART00000065143
unc-119 homolog b (C. elegans)
chr5_+_38225036 0.45 ENSDART00000076835
mitochondrial ribosomal protein L1
chr19_+_32614657 0.45 ENSDART00000022667
family with sequence similarity 8, member A1a
chr14_-_14353451 0.44 ENSDART00000170355
ENSDART00000159888
NAD(P) dependent steroid dehydrogenase-like
chr5_-_47323844 0.44 ENSDART00000145665
ENSDART00000007057
cyclin H
chr7_-_30353041 0.43 ENSDART00000173828
ring finger protein 111
chr3_+_36970806 0.42 ENSDART00000055228
PSMC3 interacting protein
chr6_+_33092094 0.42 ENSDART00000122242
protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
chr8_+_48954402 0.42

chr5_+_61711614 0.41 ENSDART00000082965
active BCR-related
chr1_+_11381915 0.41 ENSDART00000055566
xeroderma pigmentosum, complementation group A
chr9_-_21677941 0.41 ENSDART00000121939
ENSDART00000080404
M-phase phosphoprotein 8
chr25_-_19927083 0.41 ENSDART00000140182
CCR4-NOT transcription complex, subunit 4a
chr13_+_50167216 0.41 ENSDART00000178572
ENSDARG00000108623
chr25_-_8548430 0.41 ENSDART00000155280
GDP-D-glucose phosphorylase 1
chr14_+_7596207 0.41 ENSDART00000113299
zgc:110843
chr20_-_3220475 0.40 ENSDART00000123331
serine peptidase inhibitor, Kunitz type 1 b
chr5_-_27416678 0.40 ENSDART00000078642
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr23_+_44795356 0.39 ENSDART00000145905
enolase 3, (beta, muscle)
chr25_-_19926991 0.39 ENSDART00000140182
CCR4-NOT transcription complex, subunit 4a
chr13_+_28655433 0.39 ENSDART00000039028
NSE4 homolog A, SMC5-SMC6 complex component
chr7_-_19274727 0.38 ENSDART00000114203
mannosidase, alpha, class 2B, member 2
chr18_-_21695887 0.38 ENSDART00000019861
ENSDART00000114292
membrane-bound transcription factor peptidase, site 1
chr20_+_34248925 0.38 ENSDART00000145852
actin related protein 2/3 complex, subunit 5B
chr23_-_7191380 0.38 ENSDART00000176914
solute carrier organic anion transporter family, member 4A1
chr1_+_10423544 0.38 ENSDART00000109858
kinetochore-localized astrin/SPAG5 binding protein
chr10_+_24721139 0.38 ENSDART00000144710
transmembrane phosphatase with tensin homology
chr17_-_20159972 0.37

chr19_-_27958005 0.37 ENSDART00000114301
si:ch211-152p11.4
chr20_-_14784875 0.37 ENSDART00000063857
secernin 2
chr12_-_3042573 0.37 ENSDART00000002867
ENSDART00000126315
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr14_+_31189237 0.36 ENSDART00000053026
family with sequence similarity 122B
chr2_-_31728072 0.36 ENSDART00000113498
leucine rich repeat and coiled-coil centrosomal protein 1
chr3_-_47294091 0.36

chr16_+_22114192 0.36 ENSDART00000167919
zinc finger protein 687a
chr25_-_24150237 0.35 ENSDART00000073527
SPT2 chromatin protein domain containing 1
chr3_+_62116865 0.35 ENSDART00000112428
IQ motif containing K
chr24_-_36382704 0.35 ENSDART00000154858
si:ch211-40k21.5
chr21_+_21871674 0.35

chr23_-_27318392 0.35

chr13_+_8509927 0.34 ENSDART00000140489
epithelial cell adhesion molecule
chr18_-_15300493 0.34 ENSDART00000048206
transmembrane protein 263
chr20_+_27813565 0.33 ENSDART00000008306
zinc finger and BTB domain containing 1
chr25_-_8548290 0.33 ENSDART00000155280
GDP-D-glucose phosphorylase 1
chr19_-_6503643 0.33

chr11_-_8116319 0.32 ENSDART00000101561
tubulin tyrosine ligase-like family, member 7
chr10_-_26202233 0.31 ENSDART00000136472
tripartite motif containing 3b
chr14_+_6656429 0.31 ENSDART00000150050
heterogeneous nuclear ribonucleoprotein A/Ba
chr14_+_21874825 0.31 ENSDART00000114750
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr11_+_24060826 0.31 ENSDART00000138487
si:dkey-76p14.2
chr14_-_23504183 0.30 ENSDART00000054264
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr23_-_24615681 0.30 ENSDART00000132265
ATPase type 13A2
chr18_-_6011304 0.30 ENSDART00000122307
glycine cleavage system protein H (aminomethyl carrier), a
chr15_+_40130393 0.29 ENSDART00000063786
calcium binding protein 39
chr4_+_13932693 0.29 ENSDART00000142466
periphilin 1
chr19_-_20578863 0.29 ENSDART00000148179
family with sequence similarity 221, member A
chr12_+_13306551 0.28 ENSDART00000089017
ribonuclease type III, nuclear
chr20_-_3220522 0.28 ENSDART00000008077
serine peptidase inhibitor, Kunitz type 1 b
chr6_-_40411469 0.28 ENSDART00000154520
ENSDARG00000097645
chr21_-_1618494 0.28 ENSDART00000124904
zgc:152948
chr13_+_12538980 0.27 ENSDART00000010517
eukaryotic translation initiation factor 4eb
chr7_+_8492338 0.27

chr25_-_9889072 0.27 ENSDART00000137407
ENSDARG00000093575
chr1_-_25351767 0.26 ENSDART00000076120
ENSDART00000172737
G patch domain and ankyrin repeats 1
chr24_-_1014582 0.26 ENSDART00000114544
cyclin-dependent kinase 13
chr8_-_18480333 0.26 ENSDART00000149446
ENSDARG00000077696
chr19_+_12525407 0.26 ENSDART00000135706
low density lipoprotein receptor class A domain containing 4a
chr3_+_19490148 0.26

chr25_-_24150270 0.26 ENSDART00000073527
SPT2 chromatin protein domain containing 1
chr22_+_22413878 0.26 ENSDART00000147825
kinesin family member 14
chr10_+_20222743 0.26 ENSDART00000167008
protein phosphatase 3, catalytic subunit, gamma isozyme, b
chr4_-_1968907 0.25 ENSDART00000067433
ubiquitin-conjugating enzyme E2Nb
chr6_-_8156471 0.25 ENSDART00000081561
interleukin enhancer binding factor 3a
chr13_-_9737104 0.25 ENSDART00000158381
myomesin 2b
chr16_-_25765512 0.25 ENSDART00000132693
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr22_-_3165441 0.25 ENSDART00000158009
lon peptidase 1, mitochondrial
chr12_-_3630622 0.24 ENSDART00000164707
cytochrome C oxidase assembly factor 3a
chr8_+_41003629 0.24 ENSDART00000129344
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr7_+_21620944 0.24 ENSDART00000162252
POP7 homolog, ribonuclease P/MRP subunit
chr16_+_22113874 0.24 ENSDART00000170604
zinc finger protein 687a
chr25_-_10694465 0.24 ENSDART00000127054
ENSDARG00000089303
chr2_+_34675356 0.24

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.3 3.2 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.3 0.8 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.3 0.8 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.2 0.7 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.2 1.9 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.2 1.1 GO:2001287 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.2 2.9 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.2 0.8 GO:0010159 specification of organ position(GO:0010159)
0.1 1.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.4 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 0.5 GO:0051414 response to cortisol(GO:0051414) cellular response to cortisol stimulus(GO:0071387)
0.1 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 1.3 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 1.2 GO:0021592 fourth ventricle development(GO:0021592) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 1.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 2.0 GO:0051289 protein homotetramerization(GO:0051289)
0.1 0.4 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 0.7 GO:0019430 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 0.5 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.3 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.4 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.3 GO:0010990 SMAD protein complex assembly(GO:0007183) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 1.5 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.7 GO:0007584 response to nutrient(GO:0007584)
0.1 0.3 GO:0021588 cerebellum formation(GO:0021588)
0.1 1.0 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 2.3 GO:0016574 histone ubiquitination(GO:0016574)
0.1 0.2 GO:0000967 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) RNA 5'-end processing(GO:0000966) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.1 0.5 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.1 1.1 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 1.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.4 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 3.3 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.4 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 1.0 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.7 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 1.4 GO:0001878 response to yeast(GO:0001878)
0.0 0.1 GO:1902224 cellular ketone body metabolic process(GO:0046950) ketone body metabolic process(GO:1902224)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.8 GO:0051607 defense response to virus(GO:0051607)
0.0 1.0 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 0.6 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.6 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 1.6 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0051877 eye pigmentation(GO:0048069) pigment granule aggregation in cell center(GO:0051877) axis elongation involved in somitogenesis(GO:0090245)
0.0 0.1 GO:0045144 meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177) meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.1 GO:0036065 fucosylation(GO:0036065)
0.0 0.9 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 1.2 GO:0048477 oogenesis(GO:0048477)
0.0 0.5 GO:0035825 reciprocal DNA recombination(GO:0035825)
0.0 1.2 GO:0045087 innate immune response(GO:0045087)
0.0 0.5 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.2 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.0 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.2 GO:1903725 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551) regulation of phospholipid metabolic process(GO:1903725)
0.0 0.4 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0033503 HULC complex(GO:0033503)
0.2 2.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.7 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 0.3 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.1 0.6 GO:0008623 CHRAC(GO:0008623)
0.1 3.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.1 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.4 GO:0070985 TFIIK complex(GO:0070985)
0.1 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.9 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.4 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 0.6 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 1.0 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.6 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 1.9 GO:0016605 PML body(GO:0016605)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.5 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.0 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.8 GO:0030027 lamellipodium(GO:0030027)
0.0 1.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.6 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.4 1.2 GO:0004568 chitinase activity(GO:0004568)
0.4 1.9 GO:0032184 SUMO polymer binding(GO:0032184)
0.3 1.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 0.8 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.3 2.0 GO:0005522 profilin binding(GO:0005522)
0.2 3.0 GO:0019894 kinesin binding(GO:0019894)
0.2 2.9 GO:2001069 glycogen binding(GO:2001069)
0.2 1.3 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2 1.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 0.8 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2 0.7 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.2 0.7 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.8 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.7 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.4 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.5 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 1.5 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 0.3 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.6 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 1.0 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.0 1.0 GO:0022884 protein transmembrane transporter activity(GO:0008320) macromolecule transmembrane transporter activity(GO:0022884)
0.0 0.4 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.7 GO:0015926 glucosidase activity(GO:0015926)
0.0 2.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.3 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 1.8 GO:0005496 steroid binding(GO:0005496)
0.0 0.1 GO:0047611 acetylspermidine deacetylase activity(GO:0047611)
0.0 1.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 1.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.4 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.5 GO:0000149 SNARE binding(GO:0000149)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.0 GO:0016639 glutamate dehydrogenase (NAD+) activity(GO:0004352) glutamate dehydrogenase [NAD(P)+] activity(GO:0004353) oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 0.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.6 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 0.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.7 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.8 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.3 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0 0.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.5 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.6 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.2 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism