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Results for pax2b

Z-value: 1.85

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Transcription factors associated with pax2b

Gene Symbol Gene ID Gene Info
ENSDARG00000032578 paired box 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pax2bdr10_dc_chr12_-_45714172_45714180-0.758.2e-04Click!

Activity profile of pax2b motif

Sorted Z-values of pax2b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of pax2b

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_+_23704663 4.67 ENSDART00000104346
makorin, ring finger protein, 4
chr8_+_52456064 4.21 ENSDART00000012758
zgc:77112
chr19_+_15536640 4.06 ENSDART00000098970
lin-28 homolog A (C. elegans)
chr2_+_25281122 3.55 ENSDART00000025962
glycogenin 1a
chr8_-_2557556 3.45 ENSDART00000140033
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a
chr10_+_16543480 3.24 ENSDART00000121864
solute carrier family 27 (fatty acid transporter), member 6
chr24_-_24999240 3.23 ENSDART00000152104
pleckstrin homology-like domain, family B, member 2b
chr23_-_22596648 3.10 ENSDART00000079019
splA/ryanodine receptor domain and SOCS box containing 1
chr7_-_55346967 2.74 ENSDART00000135304
poly(A) binding protein, nuclear 1-like (cytoplasmic)
chr6_+_135002 2.64 ENSDART00000097468
zinc finger, GATA-like protein 1
chr11_+_12983670 2.60 ENSDART00000166126
basic transcription factor 3-like 4
chr15_+_29092022 2.60 ENSDART00000141164
si:ch211-137a8.2
chr16_+_9823111 2.58 ENSDART00000164103
extracellular matrix protein 1b
chr23_-_35384257 2.57 ENSDART00000113643
F-box protein 25
chr11_-_44539778 2.49 ENSDART00000161846
microtubule-associated protein 1 light chain 3 gamma
chr10_-_2944190 2.47 ENSDART00000132526
MARVEL domain containing 2a
chr3_-_20912934 2.45 ENSDART00000156275
family with sequence similarity 57, member Ba
chr4_+_16020464 2.44 ENSDART00000144611
ENSDARG00000093983
chr19_+_31997954 2.43 ENSDART00000164108
geminin, DNA replication inhibitor
chr3_-_32231069 2.43 ENSDART00000035545
protein arginine methyltransferase 1
chr17_+_52526741 2.37 ENSDART00000109891
angel homolog 1 (Drosophila)
chr13_+_35799681 2.36 ENSDART00000046115
major facilitator superfamily domain containing 2aa
chr13_+_35799602 2.33 ENSDART00000046115
major facilitator superfamily domain containing 2aa
chr3_-_15325357 2.25 ENSDART00000139575
spinster homolog 1 (Drosophila)
chr21_-_3548863 2.24 ENSDART00000086492
ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr16_-_55211053 2.21 ENSDART00000156533
keratinocyte differentiation factor 1a
chr1_-_55072271 2.19 ENSDART00000142244
DnaJ (Hsp40) homolog, subfamily B, member 1b
chr2_-_57339717 2.14 ENSDART00000150034
protein inhibitor of activated STAT, 4b
chr2_+_10858480 2.13 ENSDART00000091570
family with sequence similarity 69, member Aa
chr14_+_24543399 2.12 ENSDART00000106039
Rho guanine nucleotide exchange factor (GEF) 37
chr5_-_31257158 2.11 ENSDART00000112546
protein kinase N3
chr22_+_8856370 2.05 ENSDART00000178799
ENSDARG00000109049
chr16_+_9822930 2.05 ENSDART00000164103
extracellular matrix protein 1b
chr10_+_36718872 2.02 ENSDART00000063359
uncoupling protein 3
chr6_-_53145464 1.96 ENSDART00000079694
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
chr14_+_19859164 1.96 ENSDART00000123434
fragile X mental retardation 1
chr23_+_33792145 1.96 ENSDART00000024695
DAZ associated protein 2
chr8_+_28715451 1.95 ENSDART00000140115
coiled-coil serine-rich protein 1
chr22_+_37688839 1.93 ENSDART00000174664
ENSDART00000178200
ENSDARG00000108910
chr10_-_2944295 1.93 ENSDART00000132526
MARVEL domain containing 2a
chr17_+_25168837 1.92 ENSDART00000148431
CLN8, transmembrane ER and ERGIC protein
chr1_+_45015350 1.91 ENSDART00000143363
si:ch211-214c7.4
chr11_+_13118866 1.90 ENSDART00000123257
MAP kinase interacting serine/threonine kinase 1
chr10_-_45182378 1.87 ENSDART00000161815
polymerase (DNA directed), mu
chr1_+_5437327 1.86 ENSDART00000092324
ATP-binding cassette, sub-family B (MDR/TAP), member 6a
chr24_-_24999067 1.83 ENSDART00000152104
pleckstrin homology-like domain, family B, member 2b
chr12_+_19837266 1.83 ENSDART00000015780
excision repair cross-complementation group 4
chr5_-_47609402 1.83

chr8_+_40236694 1.80 ENSDART00000164414
ORAI calcium release-activated calcium modulator 1a
chr5_-_28931727 1.79 ENSDART00000174697
arrestin domain containing 1a
chr4_-_951763 1.78 ENSDART00000093289
XRCC6 binding protein 1
chr22_+_22413803 1.78 ENSDART00000147825
kinesin family member 14
chr15_+_29091983 1.76 ENSDART00000141164
si:ch211-137a8.2
chr12_-_926596 1.76 ENSDART00000088351
sperm associated antigen 9
chr3_+_42217236 1.75 ENSDART00000168228
transmembrane protein 184a
chr17_+_25163592 1.74 ENSDART00000100277
CLN8, transmembrane ER and ERGIC protein
chr2_+_15379961 1.73 ENSDART00000058484
calponin 3, acidic b
chr5_-_9036049 1.73 ENSDART00000160079
cyclin G associated kinase
chr5_-_47609309 1.73

chr10_-_24796421 1.72 ENSDART00000064463
translocase of inner mitochondrial membrane 10 homolog B (yeast)
chr6_-_8468819 1.71 ENSDART00000064149
nucleic acid binding protein 1b
chr22_-_52486 1.70

chr19_+_2942485 1.69 ENSDART00000177848
ENSDARG00000107451
chr18_+_44775449 1.68 ENSDART00000145190
ilvB (bacterial acetolactate synthase)-like
chr5_-_14000166 1.67 ENSDART00000099566
si:ch211-244o22.2
chr2_+_15379717 1.67 ENSDART00000058484
calponin 3, acidic b
chr3_+_32700459 1.66 ENSDART00000132679
ENSDART00000035759
CD2 (cytoplasmic tail) binding protein 2
chr22_-_25592743 1.65 ENSDART00000110638
ENSDART00000172092
si:ch211-12h2.8
chr3_+_16572387 1.64 ENSDART00000008711
glycogen synthase 1 (muscle)
chr23_-_24416864 1.64 ENSDART00000166392
family with sequence similarity 131, member C
chr16_+_53632289 1.63 ENSDART00000124691
sphingomyelin phosphodiesterase 5
chr6_-_10676857 1.62 ENSDART00000036456
cytochrome c, somatic b
chr13_-_7972442 1.62 ENSDART00000128005
atlastin GTPase 2
chr10_+_16543577 1.62 ENSDART00000121864
solute carrier family 27 (fatty acid transporter), member 6
chr8_+_40236654 1.61 ENSDART00000164414
ORAI calcium release-activated calcium modulator 1a
chr10_+_18953548 1.61 ENSDART00000030205
BCL2/adenovirus E1B interacting protein 3-like b
chr23_-_24416911 1.59 ENSDART00000166392
family with sequence similarity 131, member C
chr10_-_44441197 1.59 ENSDART00000160231
strawberry notch homolog 1 (Drosophila)
chr15_+_29092224 1.57 ENSDART00000131755
si:ch211-137a8.2
chr16_-_13723352 1.57 ENSDART00000139102
D site albumin promoter binding protein b
chr13_-_7972530 1.56 ENSDART00000080460
atlastin GTPase 2
chr14_+_21373857 1.55 ENSDART00000079649
ENSDART00000165795
NADH dehydrogenase (ubiquinone) Fe-S protein 8b
chr14_+_29932533 1.54 ENSDART00000017122
N-acylsphingosine amidohydrolase (acid ceramidase) 1a
chr8_-_2557506 1.53 ENSDART00000140033
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a
chr21_+_7737161 1.53

chr3_+_56882443 1.51

chr5_-_9035789 1.50 ENSDART00000124384
cyclin G associated kinase
chr19_+_791656 1.49 ENSDART00000138406
transmembrane protein 79a
chr5_-_40503137 1.48 ENSDART00000051070
golgi phosphoprotein 3
chr11_-_14044356 1.48 ENSDART00000085158
transmembrane protein 259
chr18_+_6339577 1.48 ENSDART00000136333
WAS protein family homolog 1
chr20_+_30476065 1.47 ENSDART00000062441
ribonuclease H1
chr12_-_30244575 1.46 ENSDART00000152981
tudor domain containing 1
chr8_-_40236572 1.46 ENSDART00000053158
lysine (K)-specific demethylase 2Ba
chr3_+_16772351 1.46 ENSDART00000164895
ATPase, H+ transporting, lysosomal V0 subunit a1a
chr3_-_26060787 1.46 ENSDART00000113843
yippee-like 3
chr6_+_18894174 1.46 ENSDART00000165806
serine/threonine kinase 11 interacting protein
chr9_-_11616001 1.44 ENSDART00000030995
uridine monophosphate synthetase
chr7_+_28905795 1.43 ENSDART00000146655
APH1B gamma secretase subunit
chr20_-_53835111 1.40 ENSDART00000177147
solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29
chr21_+_22364359 1.40 ENSDART00000134592
LMBR1 domain containing 2b
chr5_-_18502344 1.40 ENSDART00000137022
ENSDART00000090494
ENSDART00000165701
golgin A3
chr22_-_52569 1.39

chr21_-_19883182 1.39 ENSDART00000065670
protein phosphatase 1, regulatory subunit 3B
chr13_+_45387478 1.38 ENSDART00000019113
transmembrane protein 57b
chr12_+_19837298 1.37 ENSDART00000015780
excision repair cross-complementation group 4
chr2_+_15380054 1.37 ENSDART00000058484
calponin 3, acidic b
chr10_+_42085689 1.36 ENSDART00000009227
ORAI calcium release-activated calcium modulator 1b
chr8_+_50202152 1.34 ENSDART00000099863
solute carrier family 25 (mitochondrial iron transporter), member 37
chr7_-_9628384 1.33 ENSDART00000006343
ankyrin repeat and SOCS box containing 7
chr5_-_11530803 1.33 ENSDART00000159896
GATS protein-like 3
chr10_-_44441390 1.33 ENSDART00000160231
strawberry notch homolog 1 (Drosophila)
chr7_+_66410533 1.32 ENSDART00000027616
ENSDART00000162763
eukaryotic translation initiation factor 4, gamma 2a
chr7_+_27184121 1.32 ENSDART00000148417
cytochrome P450, family 2, subfamily R, polypeptide 1
chr8_-_22521204 1.32 ENSDART00000134542
cold shock domain containing E1, RNA-binding
chr18_-_3455211 1.31 ENSDART00000163762
DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)
chr2_+_10858655 1.31 ENSDART00000091570
family with sequence similarity 69, member Aa
chr6_-_51811024 1.31 ENSDART00000031597
proteasome inhibitor subunit 1
chr23_+_17583666 1.30 ENSDART00000054738
GID complex subunit 8 homolog b (S. cerevisiae)
chr10_+_16544000 1.30 ENSDART00000121864
solute carrier family 27 (fatty acid transporter), member 6
chr25_-_13394261 1.30 ENSDART00000056721
lactate dehydrogenase D
chr7_+_22027528 1.30 ENSDART00000056790
transmembrane protein 256
chr3_+_33608070 1.29

chr6_-_8225364 1.29

chr24_+_22614373 1.29 ENSDART00000135392
si:dkey-7n6.2
chr16_+_9822879 1.29 ENSDART00000164103
extracellular matrix protein 1b
chr16_-_13723295 1.28 ENSDART00000139102
D site albumin promoter binding protein b
chr23_+_17583383 1.28 ENSDART00000148457
GID complex subunit 8 homolog b (S. cerevisiae)
chr19_-_27239547 1.28 ENSDART00000149132
neuraminidase 1
chr11_+_44738699 1.28 ENSDART00000172301
ENSDART00000170118
thymidine kinase 1, soluble
chr13_-_50149031 1.27

chr3_+_9504996 1.27 ENSDART00000171467
si:dkey-29p9.3
chr15_+_45576378 1.26 ENSDART00000157459
ATG16 autophagy related 16-like 1 (S. cerevisiae)
chr15_-_23786063 1.26 ENSDART00000109318
zinc finger CCCH-type containing 4
chr14_+_29601046 1.25 ENSDART00000143763
family with sequence similarity 149 member A
KN149698v1_-_88818 1.25

chr22_+_25059272 1.24 ENSDART00000177284
ribosome binding protein 1b
chr25_+_30627892 1.24

chr6_-_8468961 1.24 ENSDART00000064149
nucleic acid binding protein 1b
chr4_+_25923205 1.24 ENSDART00000136927
vezatin, adherens junctions transmembrane protein
chr22_-_26537845 1.23

chr9_-_9864149 1.23 ENSDART00000121456
follistatin-like 1b
chr11_-_44738541 1.23 ENSDART00000168066
arylformamidase
chr13_-_31267133 1.23 ENSDART00000008287
phosphoglycerate mutase 1a
chr13_-_25620394 1.23 ENSDART00000111567
sphingosine-1-phosphate lyase 1
chr2_+_8314513 1.23 ENSDART00000138136
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2a
chr6_+_135255 1.23 ENSDART00000097468
zinc finger, GATA-like protein 1
chr20_+_54544851 1.23 ENSDART00000144633
CLOCK-interacting pacemaker b
chr22_+_37689055 1.21

chr13_-_35766296 1.21 ENSDART00000162399
transforming, acidic coiled-coil containing protein 3
chr20_-_26161022 1.21 ENSDART00000151950
serine active site containing 1
chr19_+_14490203 1.21 ENSDART00000164386
AT rich interactive domain 1Ab (SWI-like)
chr17_+_44327269 1.21 ENSDART00000045882
adaptor-related protein complex 5, mu 1 subunit
chr16_+_26858575 1.21 ENSDART00000138496
RAD54 homolog B (S. cerevisiae)
chr6_+_49724436 1.20 ENSDART00000154738
syntaxin 16
chr7_+_71262845 1.20 ENSDART00000100396
protein phosphatase 1, regulatory subunit 15A
chr5_-_69171508 1.19 ENSDART00000127782
UDP glucuronosyltransferase 2 family, polypeptide A1
chr20_-_40470331 1.18 ENSDART00000075096
sphingomyelin phosphodiesterase, acid-like 3A
chr10_-_24754849 1.17 ENSDART00000148582
sphingomyelin phosphodiesterase 1, acid lysosomal
chr3_-_58400345 1.17 ENSDART00000052179
cerebellar degeneration-related protein 2a
chr25_-_13774670 1.16 ENSDART00000160866
cryptochrome circadian clock 2
chr11_-_30971444 1.16 ENSDART00000170700
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing b
chr7_+_24119940 1.16 ENSDART00000108753
polymerase (DNA directed) nu
chr7_+_46970462 1.16 ENSDART00000098942
ENSDART00000162237
zinc finger protein 507
chr15_-_14102102 1.15 ENSDART00000139068
zgc:114130
chr1_-_54488824 1.15 ENSDART00000150430
proliferation associated nuclear element
chr16_+_53632152 1.15 ENSDART00000124691
sphingomyelin phosphodiesterase 5
chr19_+_34263554 1.14 ENSDART00000161290
peroxisomal biogenesis factor 1
chr4_-_16846903 1.14 ENSDART00000010777
lactate dehydrogenase Ba
chr5_-_14000289 1.13 ENSDART00000099566
si:ch211-244o22.2
chr4_+_9357791 1.13

chr21_+_20350152 1.12 ENSDART00000144366
si:dkey-30k6.5
chr8_-_31706973 1.12 ENSDART00000061832
si:dkey-46a10.3
chr8_+_50201986 1.11 ENSDART00000099863
solute carrier family 25 (mitochondrial iron transporter), member 37
chr21_+_34053739 1.11 ENSDART00000147519
myotubularin related protein 1b
chr7_-_41532268 1.11 ENSDART00000016105
ENSDART00000138800
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr17_+_49995001 1.10 ENSDART00000113644
vacuolar protein sorting 39 homolog (S. cerevisiae)
chr25_-_17282381 1.10 ENSDART00000178173
cytochrome P450, family 2, subfamily X, polypeptide 7
chr11_-_31012985 1.09 ENSDART00000162605
mannosidase, alpha, class 2B, member 1
chr19_+_14295978 1.09 ENSDART00000168260
nudC nuclear distribution protein
chr8_+_40236817 1.09 ENSDART00000164414
ORAI calcium release-activated calcium modulator 1a
chr6_+_38882608 1.08 ENSDART00000019939
bridging integrator 2b
chr3_-_29837017 1.08 ENSDART00000139310
branched chain amino-acid transaminase 2, mitochondrial
chr24_-_21758198 1.08 ENSDART00000091252
spermatogenesis associated 13
chr4_-_7867294 1.08 ENSDART00000167943
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr14_+_29601073 1.07 ENSDART00000143763
family with sequence similarity 149 member A
chr3_-_54245542 1.07 ENSDART00000124215
thyroid hormone receptor interactor 10a
chr5_+_56896961 1.07

chr16_+_17762256 1.06 ENSDART00000128672
transmembrane protein 238b
chr6_-_41141242 1.06 ENSDART00000128723
ENSDART00000151055
solute carrier family 6 member 22, tandem duplicate 1
chr9_-_21729953 1.06

chr20_-_223222 1.06 ENSDART00000104790
zinc finger protein 292b
chr19_-_35400339 1.05

chr23_-_31986679 1.05 ENSDART00000085054
mitochondrial fission regulator 2
chr17_+_15891060 1.05 ENSDART00000154181
spectrin repeat containing, nuclear envelope family member 3
chr13_-_23825787 1.05 ENSDART00000101150
phosphatase and actin regulator 2
chr13_+_40566900 1.04 ENSDART00000057047
Hermansky-Pudlak syndrome 1
chr5_-_66687335 1.04 ENSDART00000062359
uracil DNA glycosylase a
chr18_+_6417959 1.04 ENSDART00000110892
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr9_+_34571082 1.04 ENSDART00000131705
lysosomal-associated membrane protein 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.3 GO:1990379 maintenance of blood-brain barrier(GO:0035633) lysophospholipid transport(GO:0051977) lipid transport across blood brain barrier(GO:1990379)
0.9 5.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.8 2.5 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.7 2.9 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.7 2.9 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.7 3.6 GO:0072319 clathrin coat disassembly(GO:0072318) vesicle uncoating(GO:0072319)
0.7 2.1 GO:1903523 negative regulation of heart contraction(GO:0045822) negative regulation of blood circulation(GO:1903523)
0.7 2.8 GO:0061072 iris morphogenesis(GO:0061072)
0.7 2.0 GO:0090365 regulation of mRNA modification(GO:0090365)
0.6 3.2 GO:1901255 nucleotide-excision repair involved in interstrand cross-link repair(GO:1901255)
0.6 2.2 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.6 2.8 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) valine biosynthetic process(GO:0009099)
0.5 1.0 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.5 1.5 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.5 5.9 GO:0002115 store-operated calcium entry(GO:0002115)
0.4 2.2 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.4 1.3 GO:0071305 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.4 0.4 GO:0032885 regulation of polysaccharide biosynthetic process(GO:0032885)
0.4 2.0 GO:0010922 positive regulation of phosphatase activity(GO:0010922) positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.4 3.6 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.4 2.7 GO:0007220 Notch receptor processing(GO:0007220)
0.4 1.5 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.3 9.8 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.3 1.0 GO:1903232 melanosome assembly(GO:1903232)
0.3 5.9 GO:0070167 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.3 1.9 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.3 1.0 GO:1902908 regulation of melanosome transport(GO:1902908)
0.3 0.9 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.3 1.2 GO:0010656 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.3 1.8 GO:0039703 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.3 0.9 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.3 1.1 GO:0008057 eye pigment granule organization(GO:0008057)
0.3 0.8 GO:0071800 podosome assembly(GO:0071800)
0.3 7.7 GO:0097352 autophagosome maturation(GO:0097352)
0.3 1.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.3 2.0 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.2 0.7 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.2 0.7 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.2 6.3 GO:0015908 fatty acid transport(GO:0015908)
0.2 3.2 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.2 0.9 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.2 1.5 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.2 0.6 GO:0061511 centriole elongation(GO:0061511)
0.2 0.8 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.2 2.0 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.2 2.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 2.1 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.2 2.3 GO:0071875 adrenergic receptor signaling pathway(GO:0071875)
0.2 0.6 GO:0002504 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.2 0.6 GO:0051096 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.2 1.3 GO:2000480 regulation of cAMP-dependent protein kinase activity(GO:2000479) negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 0.7 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.2 1.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 0.5 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.2 1.0 GO:0021744 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.2 2.0 GO:0051181 cofactor transport(GO:0051181)
0.2 1.2 GO:0070987 error-free translesion synthesis(GO:0070987)
0.2 0.5 GO:0007624 ultradian rhythm(GO:0007624)
0.2 3.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.2 2.7 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.2 2.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.2 0.8 GO:0006528 asparagine metabolic process(GO:0006528)
0.1 0.6 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.6 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 2.1 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 4.8 GO:0048599 oocyte development(GO:0048599)
0.1 0.8 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.1 1.1 GO:0006013 mannose metabolic process(GO:0006013)
0.1 5.4 GO:0007605 sensory perception of sound(GO:0007605)
0.1 0.4 GO:0070922 small RNA loading onto RISC(GO:0070922)
0.1 0.5 GO:2001271 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 2.0 GO:0009409 response to cold(GO:0009409)
0.1 0.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 1.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 0.4 GO:1990535 neuron projection maintenance(GO:1990535)
0.1 1.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 1.5 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.1 1.0 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 0.5 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.8 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 4.9 GO:0055088 lipid homeostasis(GO:0055088)
0.1 0.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.3 GO:0006014 D-ribose metabolic process(GO:0006014)
0.1 1.9 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.1 1.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.4 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.1 0.4 GO:1903335 regulation of vacuolar transport(GO:1903335)
0.1 0.3 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.1 1.0 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.8 GO:0046386 deoxyribonucleotide catabolic process(GO:0009264) deoxyribose phosphate catabolic process(GO:0046386)
0.1 0.7 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.6 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.1 1.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.6 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.3 GO:0051645 Golgi localization(GO:0051645)
0.1 0.5 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 2.6 GO:0010212 response to ionizing radiation(GO:0010212)
0.1 0.3 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.3 GO:0001715 ectodermal cell fate commitment(GO:0001712) ectodermal cell fate specification(GO:0001715) ectodermal cell differentiation(GO:0010668) regulation of ectodermal cell fate specification(GO:0042665) regulation of ectoderm development(GO:2000383)
0.1 0.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.3 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.2 GO:0043393 regulation of protein binding(GO:0043393)
0.1 0.6 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.2 GO:2000622 negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 1.0 GO:0042407 cristae formation(GO:0042407)
0.1 0.4 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.6 GO:1901314 regulation of histone ubiquitination(GO:0033182) negative regulation of histone ubiquitination(GO:0033183) histone H2A K63-linked ubiquitination(GO:0070535) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.3 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627) mitochondrial protein processing(GO:0034982)
0.1 3.3 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 2.2 GO:0051084 'de novo' protein folding(GO:0006458) 'de novo' posttranslational protein folding(GO:0051084)
0.1 2.1 GO:0048263 determination of dorsal identity(GO:0048263)
0.1 1.0 GO:0016233 telomere capping(GO:0016233)
0.1 0.7 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 0.6 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 1.0 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.8 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 0.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307) oxidative DNA demethylation(GO:0035511)
0.1 0.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.2 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1 1.0 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1 1.3 GO:0006213 pyrimidine nucleoside metabolic process(GO:0006213)
0.1 1.4 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.2 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) RNA 5'-end processing(GO:0000966) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.1 0.8 GO:0048696 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.1 0.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 3.0 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 1.9 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 0.6 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.1 0.3 GO:0045144 meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177) meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.2 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.8 GO:0014823 response to activity(GO:0014823)
0.0 0.7 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 1.5 GO:0072665 protein localization to vacuole(GO:0072665)
0.0 0.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.4 GO:0051256 mitotic spindle elongation(GO:0000022) positive regulation of cytokinesis(GO:0032467) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.0 0.4 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
0.0 6.3 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.4 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.7 GO:0044042 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) energy reserve metabolic process(GO:0006112) glucan metabolic process(GO:0044042)
0.0 1.4 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.0 0.3 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.0 0.3 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 1.7 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 1.8 GO:0007283 spermatogenesis(GO:0007283)
0.0 0.4 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.8 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.7 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.9 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.4 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.5 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.9 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.2 GO:0046323 glucose import(GO:0046323)
0.0 1.3 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.8 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.6 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 2.2 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 0.2 GO:0001743 optic placode formation(GO:0001743) optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 1.3 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 1.2 GO:0072329 monocarboxylic acid catabolic process(GO:0072329)
0.0 0.5 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.1 GO:1903288 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.8 GO:0007281 germ cell development(GO:0007281)
0.0 1.2 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.4 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.7 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.3 GO:0051180 vitamin transport(GO:0051180)
0.0 0.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.3 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.4 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.4 GO:0046466 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.0 0.2 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.2 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.0 1.0 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.6 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 1.5 GO:0006413 translational initiation(GO:0006413)
0.0 0.4 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.4 GO:0035082 axoneme assembly(GO:0035082)
0.0 1.6 GO:0006631 fatty acid metabolic process(GO:0006631)
0.0 1.1 GO:0016197 endosomal transport(GO:0016197)
0.0 0.3 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.1 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 1.0 GO:0045055 regulated exocytosis(GO:0045055)
0.0 0.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.6 GO:0007030 Golgi organization(GO:0007030)
0.0 0.5 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0061689 tricellular tight junction(GO:0061689)
0.8 2.5 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.7 2.0 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.6 7.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.5 3.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.5 3.0 GO:0070876 SOSS complex(GO:0070876)
0.5 2.7 GO:0070765 gamma-secretase complex(GO:0070765)
0.4 7.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.4 1.9 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.3 1.0 GO:0031085 BLOC-3 complex(GO:0031085)
0.3 1.0 GO:1990879 CST complex(GO:1990879)
0.3 3.9 GO:0045180 basal cortex(GO:0045180)
0.3 0.8 GO:0001891 phagocytic cup(GO:0001891)
0.2 0.7 GO:0061574 ASAP complex(GO:0061574)
0.2 1.8 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2 1.5 GO:0071546 pi-body(GO:0071546)
0.2 0.7 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 0.6 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 1.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.9 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 1.5 GO:0035060 brahma complex(GO:0035060)
0.1 0.4 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 3.7 GO:0000421 autophagosome membrane(GO:0000421)
0.1 2.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.6 GO:0061617 MICOS complex(GO:0061617)
0.1 1.0 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 2.1 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.1 0.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.5 GO:0031415 NatA complex(GO:0031415)
0.1 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.1 1.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.3 GO:0005682 U5 snRNP(GO:0005682)
0.1 1.0 GO:0000813 ESCRT I complex(GO:0000813)
0.1 1.0 GO:0030904 retromer complex(GO:0030904)
0.1 2.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 3.6 GO:0031901 early endosome membrane(GO:0031901)
0.1 0.8 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 1.0 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 2.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.6 GO:0070652 HAUS complex(GO:0070652)
0.1 0.7 GO:0045178 basal plasma membrane(GO:0009925) basal part of cell(GO:0045178)
0.1 4.6 GO:0005802 trans-Golgi network(GO:0005802)
0.1 0.9 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 2.3 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 2.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 3.1 GO:0005871 kinesin complex(GO:0005871)
0.1 0.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.9 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.2 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.7 GO:0044545 NSL complex(GO:0044545)
0.0 10.2 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.1 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.8 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.5 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.5 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 1.3 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 1.0 GO:0030175 filopodium(GO:0030175)
0.0 2.6 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 1.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.9 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.7 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 4.8 GO:0005764 lysosome(GO:0005764)
0.0 0.0 GO:0031526 brush border membrane(GO:0031526)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0033179 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 1.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0005795 Golgi stack(GO:0005795)
0.0 0.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.7 GO:0031201 SNARE complex(GO:0031201)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.3 GO:0051978 lysophospholipid transporter activity(GO:0051978)
1.0 5.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.9 6.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.8 2.4 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.7 3.4 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.6 1.9 GO:0004357 glutamate-cysteine ligase activity(GO:0004357) glutamate binding(GO:0016595)
0.6 2.5 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.5 2.8 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.4 5.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.4 5.9 GO:2001069 glycogen binding(GO:2001069)
0.4 2.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.4 1.7 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.4 1.2 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.4 3.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.4 1.5 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.4 1.5 GO:0034584 piRNA binding(GO:0034584)
0.4 1.1 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.4 2.5 GO:0097001 sphingolipid binding(GO:0046625) ceramide binding(GO:0097001)
0.4 1.8 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.3 2.0 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 2.0 GO:0015616 DNA translocase activity(GO:0015616)
0.3 1.0 GO:0030626 U12 snRNA binding(GO:0030626)
0.3 2.9 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.3 0.9 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.3 3.5 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.3 0.5 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.3 1.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 0.7 GO:0043531 ADP binding(GO:0043531)
0.2 1.0 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.2 1.0 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 3.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 0.7 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.2 0.7 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.2 0.7 GO:0008465 glycerate dehydrogenase activity(GO:0008465)
0.2 0.8 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2 1.2 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.2 1.0 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.2 1.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 1.0 GO:0046922 peptide-O-fucosyltransferase activity(GO:0046922)
0.2 0.6 GO:0008384 IkappaB kinase activity(GO:0008384)
0.2 1.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 5.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 3.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 0.7 GO:0004061 arylformamidase activity(GO:0004061)
0.2 1.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.2 1.8 GO:0051117 ATPase binding(GO:0051117)
0.2 2.0 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 1.4 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.2 0.5 GO:0004348 glucosylceramidase activity(GO:0004348)
0.2 1.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 0.6 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.2 0.5 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.2 0.6 GO:0008061 chitin binding(GO:0008061)
0.1 1.6 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 5.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.1 0.4 GO:0004044 amidophosphoribosyltransferase activity(GO:0004044)
0.1 1.0 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1 1.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.8 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.1 0.5 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.1 2.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.6 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 1.0 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 1.2 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 0.6 GO:0042287 MHC protein binding(GO:0042287)
0.1 1.9 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.4 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.4 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.1 0.6 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.3 GO:0035514 DNA demethylase activity(GO:0035514)
0.1 0.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 2.9 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 0.7 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 2.9 GO:0030674 protein binding, bridging(GO:0030674)
0.1 0.8 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.2 GO:0003874 6-pyruvoyltetrahydropterin synthase activity(GO:0003874)
0.1 2.8 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 0.4 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 1.6 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.1 0.8 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 1.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.8 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 0.8 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.3 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 0.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 2.2 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.1 1.1 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 1.9 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 5.5 GO:0005516 calmodulin binding(GO:0005516)
0.1 0.2 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 2.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.2 GO:0071949 FAD binding(GO:0071949)
0.0 0.2 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.4 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.6 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.5 GO:0004622 lysophospholipase activity(GO:0004622) lysophosphatidic acid acyltransferase activity(GO:0042171)
0.0 0.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 2.0 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 1.8 GO:0030276 clathrin binding(GO:0030276)
0.0 0.7 GO:0016229 steroid dehydrogenase activity(GO:0016229)
0.0 0.1 GO:0019869 chloride channel regulator activity(GO:0017081) chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 2.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 2.1 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 5.0 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 2.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.0 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.0 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140) succinate transmembrane transporter activity(GO:0015141)
0.0 2.4 GO:0005543 phospholipid binding(GO:0005543)
0.0 2.1 GO:0016757 transferase activity, transferring glycosyl groups(GO:0016757)
0.0 2.0 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 1.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 0.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 2.9 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 1.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 1.9 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 2.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 1.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 1.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 1.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.2 PID AURORA A PATHWAY Aurora A signaling
0.1 1.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.0 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 1.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.4 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 3.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.3 PID ATM PATHWAY ATM pathway
0.0 0.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.5 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.1 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.0 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.4 2.7 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.3 1.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.3 4.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.3 5.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2 1.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 1.0 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 0.8 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.2 3.1 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 1.9 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.5 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.1 1.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 0.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 3.1 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 1.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 1.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 0.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 0.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.3 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 3.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 2.7 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.1 1.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 0.7 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 1.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 0.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.9 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.8 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 1.2 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 1.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.9 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 3.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.0 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 1.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein