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Results for pax3a+pax3b

Z-value: 1.45

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Transcription factors associated with pax3a+pax3b

Gene Symbol Gene ID Gene Info
pax3a
ENSDARG00000010192 paired box 3a
pax3b
ENSDARG00000028348 paired box 3b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pax3bdr10_dc_chr15_-_42250788_42250820-0.943.8e-08Click!
pax3adr10_dc_chr2_-_47578695_47578757-0.931.7e-07Click!

Activity profile of pax3a+pax3b motif

Sorted Z-values of pax3a+pax3b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of pax3a+pax3b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr7_-_24249672 7.16 ENSDART00000077039
faah2b
fatty acid amide hydrolase 2b
chr12_+_22551105 5.79 ENSDART00000123808
ENSDART00000159864
cdca9
cell division cycle associated 9
chr10_-_34971985 5.53 ENSDART00000141201
ccna1
cyclin A1
chr8_-_410190 4.38 ENSDART00000151155
trim36
tripartite motif containing 36
chr6_-_53145464 4.23 ENSDART00000079694
gnai2b
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
chr7_-_24249630 3.71 ENSDART00000077039
faah2b
fatty acid amide hydrolase 2b
chr12_-_14104939 3.53 ENSDART00000152742
buc2l
bucky ball 2-like
chr1_+_11508857 3.45 ENSDART00000172334
ENSDART00000112171
tdrd7a
tudor domain containing 7 a
chr14_-_21320696 3.43 ENSDART00000043162
reep2
receptor accessory protein 2
chr7_-_24724911 3.21 ENSDART00000173791
rcor2
REST corepressor 2
chr22_+_8856370 3.17 ENSDART00000178799
CABZ01046433.1
ENSDARG00000109049
chr16_+_9822930 3.15 ENSDART00000164103
ecm1b
extracellular matrix protein 1b
chr5_+_21902777 3.10 ENSDART00000141385
si:dkey-27p18.3
si:dkey-27p18.3
chr16_+_9823111 2.77 ENSDART00000164103
ecm1b
extracellular matrix protein 1b
chr8_-_410293 2.55 ENSDART00000164886
trim36
tripartite motif containing 36
chr7_+_27184121 2.51 ENSDART00000148417
cyp2r1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr10_-_34971926 2.51 ENSDART00000141201
ccna1
cyclin A1
chr20_-_36510718 2.40

chr25_-_13394261 2.29 ENSDART00000056721
ldhd
lactate dehydrogenase D
chr22_+_62610 2.22 ENSDART00000062264
sdhb
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr11_+_2615745 2.21 ENSDART00000160777
b3galt6
UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
chr10_+_16543480 2.20 ENSDART00000121864
slc27a6
solute carrier family 27 (fatty acid transporter), member 6
chr6_-_53145335 2.15 ENSDART00000079694
gnai2b
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
chr6_-_53145582 2.03 ENSDART00000079694
gnai2b
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
chr1_+_50893368 2.01 ENSDART00000152789
etaa1
ETAA1, ATR kinase activator
chr4_+_4825461 1.98 ENSDART00000150309
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr22_-_760140 1.96 ENSDART00000019155
btg2
B-cell translocation gene 2
chr20_-_18482817 1.86 ENSDART00000159636
vipas39
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
chr2_-_4191540 1.80 ENSDART00000158335
rab18b
RAB18B, member RAS oncogene family
chr1_+_25911314 1.77 ENSDART00000011645
coro2a
coronin, actin binding protein, 2A
chr1_+_57878303 1.77 ENSDART00000162460
si:ch73-221f6.3
si:ch73-221f6.3
chr16_+_9822879 1.77 ENSDART00000164103
ecm1b
extracellular matrix protein 1b
chr21_-_19883182 1.74 ENSDART00000065670
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr14_-_20940726 1.72 ENSDART00000129743
si:ch211-175m2.5
si:ch211-175m2.5
chr24_-_20063951 1.68 ENSDART00000139329
cry-dash
cryptochrome DASH
chr10_+_38720500 1.67 ENSDART00000067448
acat1
acetyl-CoA acetyltransferase 1
chr12_+_18849010 1.65 ENSDART00000078494
l3mbtl2
l(3)mbt-like 2 (Drosophila)
chr8_-_47215582 1.65 ENSDART00000147606
ppih
peptidylprolyl isomerase H (cyclophilin H)
chr1_+_45907424 1.65 ENSDART00000053240
cab39l
calcium binding protein 39-like
chr21_-_2261849 1.62 ENSDART00000172041
ENSDART00000161554
si:ch73-299h12.4
si:ch73-299h12.4
chr2_-_47766563 1.59 ENSDART00000038228
ap1s3b
adaptor-related protein complex 1, sigma 3 subunit, b
chr12_+_18848952 1.59 ENSDART00000153235
l3mbtl2
l(3)mbt-like 2 (Drosophila)
chr4_-_7861030 1.56 ENSDART00000067339
mcm10
minichromosome maintenance 10 replication initiation factor
chr21_-_19882766 1.51 ENSDART00000147396
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr7_+_20091996 1.49 ENSDART00000138786
ponzr1
plac8 onzin related protein 1
chr23_-_33753484 1.47 ENSDART00000138416
tfcp2
transcription factor CP2
chr11_+_5724343 1.45 ENSDART00000172911
r3hdm4
R3H domain containing 4
KN150137v1_+_17956 1.39 ENSDART00000164745
BPHL
biphenyl hydrolase like
chr5_+_12894381 1.39 ENSDART00000051669
tctn2
tectonic family member 2
chr20_+_27398061 1.38 ENSDART00000153440
BX255913.1
ENSDARG00000096709
chr12_-_926596 1.38 ENSDART00000088351
SPAG9 (1 of many)
sperm associated antigen 9
chr15_-_41732606 1.35 ENSDART00000059327
spsb4b
splA/ryanodine receptor domain and SOCS box containing 4b
chr1_+_57891538 1.33 ENSDART00000158425
FO704618.1
ENSDARG00000105176
chr10_+_16543577 1.32 ENSDART00000121864
slc27a6
solute carrier family 27 (fatty acid transporter), member 6
chr20_-_50211708 1.31 ENSDART00000148892
extl3
exostosin-like glycosyltransferase 3
chr18_+_20045293 1.28 ENSDART00000139441
morf4l1
mortality factor 4 like 1
chr24_-_39315552 1.28

chr23_+_2847589 1.27 ENSDART00000156954
plcg1
phospholipase C, gamma 1
chr23_-_33848571 1.25 ENSDART00000027959
racgap1
Rac GTPase activating protein 1
chr15_-_41732430 1.24 ENSDART00000059327
spsb4b
splA/ryanodine receptor domain and SOCS box containing 4b
chr25_+_2252667 1.20 ENSDART00000172905
zmp:0000000932
zmp:0000000932
chr13_+_35730680 1.20 ENSDART00000017202
kcnk1b
potassium channel, subfamily K, member 1b
chr21_+_21871674 1.19

chr10_-_35488523 1.16

chr17_-_25813136 1.15 ENSDART00000148743
hhat
hedgehog acyltransferase
chr19_-_6503643 1.14

chr17_+_48041427 1.12 ENSDART00000160219
slc39a9
solute carrier family 39, member 9
chr21_+_10689336 1.10 ENSDART00000146248
znf532
zinc finger protein 532
chr7_+_20092235 1.09 ENSDART00000139274
ponzr1
plac8 onzin related protein 1
chr25_-_28920272 1.09 ENSDART00000166889
nptna
neuroplastin a
chr16_-_44910578 1.09 ENSDART00000157375
arhgap33
Rho GTPase activating protein 33
chr25_+_13695224 1.09 ENSDART00000159278
zgc:92873
zgc:92873
chr21_-_2261748 1.08 ENSDART00000172041
ENSDART00000161554
si:ch73-299h12.4
si:ch73-299h12.4
chr2_-_37762426 1.08 ENSDART00000144807
myo9b
myosin IXb
chr3_+_32401005 1.07 ENSDART00000150981
nosip
nitric oxide synthase interacting protein
chr15_-_41732304 1.06 ENSDART00000143447
spsb4b
splA/ryanodine receptor domain and SOCS box containing 4b
chr4_+_4825409 1.03 ENSDART00000150309
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr8_-_47215639 1.02 ENSDART00000147606
ppih
peptidylprolyl isomerase H (cyclophilin H)
chr21_+_22293328 0.98 ENSDART00000157839
nadk2
NAD kinase 2, mitochondrial
chr5_-_26349966 0.98 ENSDART00000050542
htra4
HtrA serine peptidase 4
chr19_+_2834491 0.97 ENSDART00000112414
rapgef5a
Rap guanine nucleotide exchange factor (GEF) 5a
chr17_+_32412739 0.97 ENSDART00000156197
CR627496.1
ENSDARG00000097538
chr9_+_31265296 0.94 ENSDART00000132478
BX470183.1
ENSDARG00000095476
chr10_+_39972154 0.94 ENSDART00000003435
smfn
small fragment nuclease
chr3_-_14421675 0.94 ENSDART00000137197
swsap1
SWIM-type zinc finger 7 associated protein 1
chr12_+_37039816 0.92 ENSDART00000162922
CR456627.1
ENSDARG00000104543
chr18_+_20044862 0.91 ENSDART00000139441
morf4l1
mortality factor 4 like 1
chr8_+_26391153 0.89 ENSDART00000053447
ifrd2
interferon-related developmental regulator 2
chr6_-_16267327 0.86 ENSDART00000089445
agap1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr10_+_16544000 0.84 ENSDART00000121864
slc27a6
solute carrier family 27 (fatty acid transporter), member 6
chr3_-_15861110 0.84 ENSDART00000080672
mrps34
mitochondrial ribosomal protein S34
chr10_+_43578519 0.83 ENSDART00000132486
rasa1b
RAS p21 protein activator (GTPase activating protein) 1b
chr17_+_25163592 0.82 ENSDART00000100277
cln8
CLN8, transmembrane ER and ERGIC protein
chr18_+_20045221 0.79 ENSDART00000139441
morf4l1
mortality factor 4 like 1
chr4_-_14894468 0.77

chr7_+_28773716 0.75 ENSDART00000086871
gfod2
glucose-fructose oxidoreductase domain containing 2
chr6_-_1315025 0.74

chr15_-_41732512 0.72 ENSDART00000059327
spsb4b
splA/ryanodine receptor domain and SOCS box containing 4b
chr7_+_23881828 0.72 ENSDART00000076735
lrp10
low density lipoprotein receptor-related protein 10
chr25_-_12838540 0.72 ENSDART00000167362
ccl39.7
chemokine (C-C motif) ligand 39, duplicate 7
chr3_-_36235222 0.70 ENSDART00000028883
gna13b
guanine nucleotide binding protein (G protein), alpha 13b
chr15_-_23786239 0.70 ENSDART00000109318
zc3h4
zinc finger CCCH-type containing 4
chr12_+_2769741 0.66 ENSDART00000178262
mms19
MMS19 homolog, cytosolic iron-sulfur assembly component
chr8_+_49103201 0.66 ENSDART00000032355
zgc:56525
zgc:56525
chr13_+_21543950 0.65 ENSDART00000078567
ENSDART00000165166
mtg1
mitochondrial ribosome-associated GTPase 1
chr4_+_4825628 0.64 ENSDART00000150309
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr14_+_1106141 0.64 ENSDART00000106708
sec24b
SEC24 homolog B, COPII coat complex component
chr18_+_45648360 0.63 ENSDART00000010256
eif3m
eukaryotic translation initiation factor 3, subunit M
chr22_+_25911875 0.63 ENSDART00000157842
dnaja3b
DnaJ (Hsp40) homolog, subfamily A, member 3B
chr8_+_24721104 0.63 ENSDART00000126897
lamtor5
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
chr21_+_2728070 0.62

chr23_+_44795356 0.60 ENSDART00000145905
eno3
enolase 3, (beta, muscle)
chr6_+_37551455 0.59 ENSDART00000160960
ENSDART00000039934
ENSDART00000136585
slc9a7
solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
chr2_-_47020452 0.58

chr19_+_33506239 0.57 ENSDART00000019459
fam91a1
family with sequence similarity 91, member A1
chr3_+_32400841 0.57 ENSDART00000150981
nosip
nitric oxide synthase interacting protein
chr24_-_31155315 0.56 ENSDART00000168398
hccsb
holocytochrome c synthase b
chr6_-_1315162 0.55

chr18_-_5004815 0.53

chr2_+_2977250 0.53

chr8_-_48858897 0.53 ENSDART00000122458
ENSDART00000010591
wrap73
WD repeat containing, antisense to TP73
chr17_+_20549925 0.52 ENSDART00000113936
ENSDARG00000074663
ENSDARG00000074663
chr7_-_44631642 0.52 ENSDART00000124342
fam96b
family with sequence similarity 96, member B
chr15_-_41732567 0.51 ENSDART00000059327
spsb4b
splA/ryanodine receptor domain and SOCS box containing 4b
chr15_+_847111 0.50 ENSDART00000158679
si:dkey-7i4.13
si:dkey-7i4.13
chr19_-_18672697 0.49

chr1_+_57891569 0.45 ENSDART00000158425
FO704618.1
ENSDARG00000105176
chr16_+_42383980 0.45

chr10_+_45056951 0.43 ENSDART00000158553
ENSDARG00000101143
ENSDARG00000101143
chr25_-_35595100 0.41

chr25_-_22954929 0.41 ENSDART00000024633
dusp8a
dual specificity phosphatase 8a
chr5_-_40542596 0.41 ENSDART00000134891
zfr
zinc finger RNA binding protein
chr20_-_51494625 0.40 ENSDART00000098833
nfkbie
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr8_-_410733 0.40 ENSDART00000151255
trim36
tripartite motif containing 36
chr21_-_11274574 0.37 ENSDART00000151000
ENSDART00000151465
zgc:162472
zgc:162472
chr9_-_46609148 0.36

chr24_-_39315521 0.30

chr4_+_75469488 0.30 ENSDART00000144892
znf1009
zinc finger protein 1009
chr23_-_33753634 0.30 ENSDART00000138416
tfcp2
transcription factor CP2
chr14_+_21725253 0.29 ENSDART00000149121
clcf1
cardiotrophin-like cytokine factor 1
chr16_+_10950751 0.22 ENSDART00000128762
dedd1
death effector domain-containing 1
chr19_+_4128351 0.13 ENSDART00000161676
bty
bloodthirsty
chr8_-_47215701 0.12 ENSDART00000060883
ppih
peptidylprolyl isomerase H (cyclophilin H)
chr3_+_35478909 0.11 ENSDART00000132703
traf7
TNF receptor-associated factor 7
chr7_-_32859341 0.10 ENSDART00000127006
ENSDART00000143768
mns1
meiosis-specific nuclear structural 1
chr3_-_40020899 0.10 ENSDART00000025285
drg2
developmentally regulated GTP binding protein 2
chr13_+_37527958 0.08 ENSDART00000141988
phf3
PHD finger protein 3
chr18_+_2902170 0.07 ENSDART00000170827
ccpg1
cell cycle progression 1
chr6_-_1315096 0.06

chr8_+_31325461 0.06

chr17_+_12504341 0.06 ENSDART00000139918
gpn1
GPN-loop GTPase 1
chr24_-_21740552 0.06

chr16_+_10950160 0.04 ENSDART00000065467
dedd1
death effector domain-containing 1
chr6_-_16267239 0.03 ENSDART00000089445
agap1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr20_+_41123859 0.03 ENSDART00000146052
man1a1
mannosidase, alpha, class 1A, member 1
chr5_+_23651005 0.02 ENSDART00000089851
slc25a15b
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 8.4 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.8 2.5 GO:0070640 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.8 3.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.6 3.0 GO:0043968 histone H2A acetylation(GO:0043968)
0.5 2.0 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.4 7.7 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.4 1.3 GO:0035474 selective angioblast sprouting(GO:0035474)
0.4 2.3 GO:0072329 monocarboxylic acid catabolic process(GO:0072329)
0.3 3.4 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.3 3.4 GO:0030719 P granule organization(GO:0030719)
0.3 2.4 GO:0072088 renal tubule morphogenesis(GO:0061333) nephron tubule morphogenesis(GO:0072078) nephron epithelium morphogenesis(GO:0072088)
0.2 0.7 GO:0003262 endocardial progenitor cell migration to the midline involved in heart field formation(GO:0003262)
0.2 1.8 GO:0034389 lipid particle organization(GO:0034389)
0.2 1.4 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.2 1.0 GO:0006741 NADP biosynthetic process(GO:0006741)
0.2 0.7 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168)
0.2 3.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.6 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 4.3 GO:0015908 fatty acid transport(GO:0015908)
0.1 0.7 GO:0002548 monocyte chemotaxis(GO:0002548) response to interferon-gamma(GO:0034341) cellular response to interferon-gamma(GO:0071346)
0.1 1.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 8.0 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 2.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.6 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 3.5 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.1 12.5 GO:0016042 lipid catabolic process(GO:0016042)
0.1 0.6 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 6.3 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.1 0.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 1.1 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 3.1 GO:0016575 histone deacetylation(GO:0016575)
0.1 1.6 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.3 GO:0048680 tyrosine phosphorylation of STAT protein(GO:0007260) regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531) positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.8 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 1.2 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.6 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 1.9 GO:0007283 spermatogenesis(GO:0007283)
0.0 0.8 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 2.0 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 7.3 GO:0051726 regulation of cell cycle(GO:0051726)
0.0 1.1 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.8 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.6 GO:0009408 response to heat(GO:0009408)
0.0 0.8 GO:0032543 mitochondrial translation(GO:0032543)
0.0 1.2 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.3 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 4.9 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.0 0.1 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.9 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.0 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.8 5.8 GO:0032133 chromosome passenger complex(GO:0032133)
0.5 1.6 GO:0031298 replication fork protection complex(GO:0031298)
0.4 3.4 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.3 0.9 GO:0097196 Shu complex(GO:0097196)
0.3 3.0 GO:0016580 Sin3 complex(GO:0016580)
0.2 0.7 GO:0097361 CIA complex(GO:0097361)
0.2 9.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 3.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 0.8 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 3.4 GO:0043186 P granule(GO:0043186)
0.1 0.6 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 1.4 GO:0036038 MKS complex(GO:0036038)
0.1 0.4 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 2.0 GO:0043596 nuclear replication fork(GO:0043596)
0.1 0.6 GO:0071986 Ragulator complex(GO:0071986)
0.1 4.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.8 GO:0005811 lipid particle(GO:0005811)
0.0 3.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 3.4 GO:0055037 recycling endosome(GO:0055037)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.1 GO:0016459 myosin complex(GO:0016459)
0.0 1.6 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.6 4.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.6 1.7 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.3 1.7 GO:0051920 peroxiredoxin activity(GO:0051920)
0.3 0.8 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.3 9.1 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2 0.7 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729) CCR5 chemokine receptor binding(GO:0031730)
0.2 3.3 GO:2001069 glycogen binding(GO:2001069)
0.2 2.8 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 10.9 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 3.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 8.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 2.2 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.1 0.8 GO:0097001 sphingolipid binding(GO:0046625) ceramide binding(GO:0097001)
0.1 0.6 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 3.2 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.0 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.1 2.5 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 0.6 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 1.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.1 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 1.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 1.7 GO:0071949 FAD binding(GO:0071949)
0.1 1.1 GO:0000146 microfilament motor activity(GO:0000146)
0.1 1.0 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 1.0 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 3.3 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 3.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.9 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 3.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.3 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 8.5 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.2 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 0.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.6 GO:0031072 heat shock protein binding(GO:0031072)
0.0 2.7 GO:0005096 GTPase activator activity(GO:0005096)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 1.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.2 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 1.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 2.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.0 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3 1.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 4.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2 1.6 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.1 2.5 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 1.6 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 2.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 1.2 REACTOME KINESINS Genes involved in Kinesins
0.1 1.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.6 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 7.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 1.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases