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Results for pax7a+pax7b+prop1

Z-value: 0.78

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Transcription factors associated with pax7a+pax7b+prop1

Gene Symbol Gene ID Gene Info
prop1
ENSDARG00000039756 PROP paired-like homeobox 1
pax7b
ENSDARG00000070818 paired box 7b
pax7a
ENSDARG00000100398 paired box 7a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pax7bdr10_dc_chr23_+_20936600_20936609-0.964.3e-09Click!
pax7adr10_dc_chr11_+_40652239_40652375-0.941.0e-07Click!

Activity profile of pax7a+pax7b+prop1 motif

Sorted Z-values of pax7a+pax7b+prop1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of pax7a+pax7b+prop1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_+_37303599 2.23 ENSDART00000097754
ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr10_-_34058331 2.14 ENSDART00000046599
zar1l
zygote arrest 1-like
chr10_+_33449922 2.06 ENSDART00000115379
ENSDART00000163458
ENSDART00000078012
zgc:153345
zgc:153345
chr10_-_25246786 1.99 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr24_+_19270877 1.99

chr22_-_20670164 1.92 ENSDART00000169077
org
oogenesis-related gene
chr8_+_45326435 1.89 ENSDART00000134161
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr21_+_6289363 1.88 ENSDART00000138600
si:ch211-225g23.1
si:ch211-225g23.1
chr16_-_24727689 1.74 ENSDART00000167121
fxyd6l
FXYD domain containing ion transport regulator 6 like
chr11_+_12754166 1.70 ENSDART00000123445
ENSDART00000163364
ENSDART00000066122
rtel1
regulator of telomere elongation helicase 1
chr16_+_47283253 1.70 ENSDART00000062507
ica1
islet cell autoantigen 1
chr2_+_6341404 1.69 ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr1_-_54391298 1.68 ENSDART00000152143
ENSDART00000152590
peli1a
pellino E3 ubiquitin protein ligase 1a
chr3_+_17562348 1.62

chr10_+_17277353 1.59 ENSDART00000038780
sppl3
signal peptide peptidase 3
chr21_-_32027717 1.58 ENSDART00000131651
ENSDARG00000073961
ENSDARG00000073961
chr9_+_8412489 1.56 ENSDART00000144851
zgc:113984
zgc:113984
chr25_+_5845303 1.48 ENSDART00000163948
ENSDARG00000053246
ENSDARG00000053246
chr4_+_4825461 1.46 ENSDART00000150309
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr21_+_22598805 1.43 ENSDART00000142495
BX510940.1
ENSDARG00000089088
chr14_+_22159893 1.41 ENSDART00000019296
gdf9
growth differentiation factor 9
chr6_-_50731449 1.38 ENSDART00000157153
pigu
phosphatidylinositol glycan anchor biosynthesis, class U
chr4_-_62022037 1.37

chr19_+_2942485 1.36 ENSDART00000177848
CABZ01066434.1
ENSDARG00000107451
chr25_+_7067115 1.33 ENSDART00000179500
BX005076.1
ENSDARG00000107609
chr14_-_14353451 1.25 ENSDART00000170355
ENSDART00000159888
nsdhl
NAD(P) dependent steroid dehydrogenase-like
chr25_+_7067043 1.23 ENSDART00000179500
BX005076.1
ENSDARG00000107609
chr25_-_13394261 1.22 ENSDART00000056721
ldhd
lactate dehydrogenase D
chr15_+_35076414 1.21 ENSDART00000165210
zgc:66024
zgc:66024
chr6_-_8156471 1.20 ENSDART00000081561
ilf3a
interleukin enhancer binding factor 3a
chr9_+_23813071 1.20

chr23_+_19663746 1.19 ENSDART00000170149
slmapb
sarcolemma associated protein b
chr15_-_16241412 1.16 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr8_-_53165501 1.16 ENSDART00000135982
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr16_+_47283374 1.15 ENSDART00000062507
ica1
islet cell autoantigen 1
chr22_+_2735606 1.14 ENSDART00000133652
si:dkey-20i20.11
si:dkey-20i20.11
chr15_+_40340914 1.13 ENSDART00000063779
efhd1
EF-hand domain family, member D1
chr20_+_54404987 1.13 ENSDART00000099338
actr10
ARP10 actin related protein 10 homolog
chr11_+_17849608 1.12 ENSDART00000020283
rpusd4
RNA pseudouridylate synthase domain containing 4
chr25_+_19302983 1.09

chr12_-_33256934 1.08 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr20_-_29961498 1.07 ENSDART00000132278
rnf144ab
ring finger protein 144ab
chr14_-_49777408 1.07 ENSDART00000166463
cnot6b
CCR4-NOT transcription complex, subunit 6b
chr8_+_11287550 1.05 ENSDART00000115057
tjp2b
tight junction protein 2b (zona occludens 2)
chr20_-_29961589 1.03 ENSDART00000132278
rnf144ab
ring finger protein 144ab
chr6_+_18941289 1.01 ENSDART00000044519
cx44.2
connexin 44.2
chr12_-_33256754 0.99 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr12_-_33256671 0.98 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr19_-_5186692 0.97 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr3_-_26675055 0.96 ENSDART00000143710
pigq
phosphatidylinositol glycan anchor biosynthesis, class Q
chr5_-_11162837 0.96

chr6_+_18941186 0.95 ENSDART00000044519
cx44.2
connexin 44.2
chr22_+_1837102 0.95 ENSDART00000163288
znf1174
zinc finger protein 1174
chr6_+_40925259 0.95 ENSDART00000002728
ENSDART00000145153
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr2_+_8314513 0.94 ENSDART00000138136
chst2a
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2a
KN150663v1_-_3381 0.94

chr11_+_6012910 0.92 ENSDART00000161001
gtpbp3
GTP binding protein 3
chr22_+_11943005 0.92 ENSDART00000105788
mgat5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr13_-_51743281 0.91

chr6_-_10676857 0.88 ENSDART00000036456
cycsb
cytochrome c, somatic b
chr11_-_44756789 0.88 ENSDART00000161712
syngr2b
synaptogyrin 2b
chr15_-_25025251 0.87 ENSDART00000109990
abhd15a
abhydrolase domain containing 15a
chr23_-_19299279 0.85 ENSDART00000080099
oard1
O-acyl-ADP-ribose deacylase 1
chr4_+_13902603 0.83 ENSDART00000137549
pphln1
periphilin 1
chr2_+_8314372 0.83 ENSDART00000138136
chst2a
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2a
chr19_-_1571878 0.81

chr10_-_17214368 0.80

chr1_+_35253862 0.79 ENSDART00000139636
zgc:152968
zgc:152968
chr19_-_18664670 0.79 ENSDART00000108627
snx10a
sorting nexin 10a
chr24_-_2454189 0.78 ENSDART00000093331
rreb1a
ras responsive element binding protein 1a
chr2_-_57826189 0.78 ENSDART00000131420
si:dkeyp-68b7.5
si:dkeyp-68b7.5
chr12_-_33257026 0.77 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr21_+_27477153 0.77 ENSDART00000065420
pacs1a
phosphofurin acidic cluster sorting protein 1a
chr21_+_21871674 0.76

chr14_+_45685886 0.75

chr12_+_22459218 0.74 ENSDART00000171725
capgb
capping protein (actin filament), gelsolin-like b
chr10_+_33450122 0.74 ENSDART00000115379
ENSDART00000163458
ENSDART00000078012
zgc:153345
zgc:153345
chr21_-_13026036 0.74 ENSDART00000135623
fam219aa
family with sequence similarity 219, member Aa
chr9_-_34700736 0.73 ENSDART00000169114
ppp2r3b
protein phosphatase 2, regulatory subunit B'', beta
chr18_+_19467527 0.73 ENSDART00000079695
zwilch
zwilch kinetochore protein
chr12_+_33257120 0.73

chr9_-_32347822 0.73 ENSDART00000037182
ankrd44
ankyrin repeat domain 44
chr4_+_4825628 0.73 ENSDART00000150309
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr6_+_18941135 0.73 ENSDART00000044519
cx44.2
connexin 44.2
chr23_-_33753484 0.73 ENSDART00000138416
tfcp2
transcription factor CP2
chr12_-_33256599 0.73 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr14_+_46362661 0.72 ENSDART00000025749
ttc9c
tetratricopeptide repeat domain 9C
chr8_+_11387135 0.72

chr1_+_13244145 0.72 ENSDART00000157563
noctb
nocturnin b
chr5_+_1109967 0.72 ENSDART00000046781
ENSDART00000163101
rnf185
ring finger protein 185
chr5_+_6005049 0.71

chr18_+_15695287 0.71

chr10_+_43953171 0.71

chr20_-_46079529 0.70 ENSDART00000153228
AL929237.3
ENSDARG00000096676
chr16_-_31386496 0.69

chr20_+_29306863 0.69 ENSDART00000141252
katnbl1
katanin p80 subunit B-like 1
chr17_-_43725091 0.68

chr17_-_21029377 0.68 ENSDART00000155300
bicc1a
BicC family RNA binding protein 1a
chr19_+_1743359 0.67 ENSDART00000166744
dennd3a
DENN/MADD domain containing 3a
chr15_-_43402935 0.66 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr6_+_27100350 0.66 ENSDART00000121558
atg4b
autophagy related 4B, cysteine peptidase
chr17_-_9794176 0.65

chr8_-_44247277 0.64

chr14_+_47190202 0.64 ENSDART00000074116
rab33ba
RAB33B, member RAS oncogene family a
chr5_-_3673698 0.64

chr24_-_21788942 0.63 ENSDART00000113092
abhd10b
abhydrolase domain containing 10b
chr20_+_25687135 0.62 ENSDART00000063122
cyp2p10
cytochrome P450, family 2, subfamily P, polypeptide 10
chr17_+_12788541 0.62 ENSDART00000016597
nfkbiab
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b
chr15_+_14656886 0.62 ENSDART00000162350
FBXO46
F-box protein 46
chr25_-_19927083 0.62 ENSDART00000140182
cnot4a
CCR4-NOT transcription complex, subunit 4a
chr22_-_10511906 0.62 ENSDART00000013933
si:dkey-42i9.4
si:dkey-42i9.4
chr21_+_31113731 0.61 ENSDART00000065366
st6gal1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr12_+_22459177 0.61 ENSDART00000171725
capgb
capping protein (actin filament), gelsolin-like b
chr19_+_2942373 0.61 ENSDART00000177848
CABZ01066434.1
ENSDARG00000107451
chr8_-_53593850 0.60

chr14_-_6901783 0.60 ENSDART00000167994
ENSDART00000166532
stox2b
storkhead box 2b
chr23_+_26099718 0.60 ENSDART00000141553
pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr17_+_32579392 0.60 ENSDART00000112559
gcfc2
GC-rich sequence DNA-binding factor 2
chr15_-_16241500 0.60 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr24_-_34794538 0.60 ENSDART00000171009
ENSDART00000170046
ctnna1
catenin (cadherin-associated protein), alpha 1
chr10_-_43874597 0.59 ENSDART00000025366
cetn3
centrin 3
KN150200v1_+_7856 0.59

chr7_+_22042296 0.59 ENSDART00000123457
TMEM102
transmembrane protein 102
chr25_-_19926991 0.59 ENSDART00000140182
cnot4a
CCR4-NOT transcription complex, subunit 4a
chr7_-_73204361 0.58 ENSDART00000157500
AL929105.1
ENSDARG00000105194
chr10_-_25808063 0.58 ENSDART00000134176
postna
periostin, osteoblast specific factor a
KN150200v1_+_7782 0.58

chr2_-_8002471 0.58 ENSDART00000146360
tbl1xr1b
transducin (beta)-like 1 X-linked receptor 1b
chr2_+_8314844 0.58 ENSDART00000138136
chst2a
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2a
chr17_-_22553428 0.58 ENSDART00000079390
exo1
exonuclease 1
chr10_+_1801745 0.58

chr20_+_46588659 0.57 ENSDART00000060695
zc3h14
zinc finger CCCH-type containing 14
chr17_-_25630635 0.57 ENSDART00000149060
ppp1cb
protein phosphatase 1, catalytic subunit, beta isozyme
chr10_-_21971084 0.57 ENSDART00000174954
CABZ01031892.1
ENSDARG00000107280
chr7_-_9628384 0.57 ENSDART00000006343
asb7
ankyrin repeat and SOCS box containing 7
chr22_+_17803347 0.57 ENSDART00000136016
hapln4
hyaluronan and proteoglycan link protein 4
chr17_+_49540985 0.57

chr20_-_46079578 0.56 ENSDART00000153228
AL929237.3
ENSDARG00000096676
chr21_-_2183869 0.56 ENSDART00000163659
zgc:162971
zgc:162971
chr21_-_25765319 0.56 ENSDART00000101219
mettl27
methyltransferase like 27
chr15_+_2556689 0.56 ENSDART00000063329
cux1b
cut-like homeobox 1b
chr16_+_12726556 0.56

chr8_-_16638825 0.56 ENSDART00000100727
osbpl9
oxysterol binding protein-like 9
chr2_+_6341345 0.55 ENSDART00000058256
zp3b
zona pellucida glycoprotein 3b
chr20_+_29306677 0.55 ENSDART00000141252
katnbl1
katanin p80 subunit B-like 1
chr22_+_10668889 0.54 ENSDART00000081228
abhd14a
abhydrolase domain containing 14A
chr19_+_10742344 0.53 ENSDART00000091813
ago3b
argonaute RISC catalytic component 3b
chr14_-_26127173 0.53 ENSDART00000088690
lman2
lectin, mannose-binding 2
chr20_-_55094208 0.53 ENSDART00000151522
si:dkey-15f23.1
si:dkey-15f23.1
chr3_-_15517844 0.53 ENSDART00000115022
zgc:66474
zgc:66474
chr12_+_10405904 0.52 ENSDART00000029133
snu13b
SNU13 homolog, small nuclear ribonucleoprotein b (U4/U6.U5)
chr1_-_17544731 0.52 ENSDART00000143157
AL929210.1
ENSDARG00000094943
chr7_+_23752492 0.52 ENSDART00000141165
tinf2
TERF1 (TRF1)-interacting nuclear factor 2
chr5_+_37303707 0.51 ENSDART00000097754
ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr20_-_33272243 0.51 ENSDART00000178752
ENSDART00000047834
nbas
neuroblastoma amplified sequence
chr23_-_15234716 0.51 ENSDART00000158943
ndrg3b
ndrg family member 3b
chr19_+_31280451 0.51 ENSDART00000047461
mfsd2ab
major facilitator superfamily domain containing 2ab
chr16_-_28723759 0.51 ENSDART00000148456
abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr22_-_37861903 0.50 ENSDART00000085931
acap2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr3_-_15517767 0.50 ENSDART00000115022
zgc:66474
zgc:66474
chr8_+_30103357 0.50 ENSDART00000133717
fancc
Fanconi anemia, complementation group C
chr22_+_1335355 0.50 ENSDART00000169629
znf45l
zinc finger 45 like
chr1_+_8010026 0.50 ENSDART00000152142
zgc:77849
zgc:77849
chr8_-_49739908 0.50 ENSDART00000138810
gkap1
G kinase anchoring protein 1
chr7_+_24374240 0.49 ENSDART00000087691
gba2
glucosidase, beta (bile acid) 2
chr22_+_35229352 0.49 ENSDART00000061315
ENSDART00000146430
tsc22d2
TSC22 domain family 2
chr4_-_2370333 0.49 ENSDART00000131046
si:ch73-278m9.1
si:ch73-278m9.1
chr6_+_56224631 0.49 ENSDART00000174612
ENSDART00000177824
FO834918.1
ENSDARG00000106015
chr13_+_40347099 0.49

chr21_-_39132507 0.48 ENSDART00000065143
unc119b
unc-119 homolog b (C. elegans)
chr9_+_8412584 0.48 ENSDART00000133880
ENSDART00000142233
zgc:113984
zgc:113984
chr17_-_21029294 0.48 ENSDART00000155300
bicc1a
BicC family RNA binding protein 1a
chr6_-_9440411 0.48 ENSDART00000169915
nop58
NOP58 ribonucleoprotein homolog (yeast)
chr4_-_20119812 0.48 ENSDART00000100867
fam3c
family with sequence similarity 3, member C
chr15_-_25025058 0.48 ENSDART00000109990
abhd15a
abhydrolase domain containing 15a
chr24_-_17261929 0.48 ENSDART00000153858
BX005392.2
ENSDARG00000096996
chr16_+_9835124 0.47 ENSDART00000020859
pip5k1ab
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b
chr23_+_43968576 0.47 ENSDART00000024313
rnf150b
ring finger protein 150b
chr21_-_4913068 0.47 ENSDART00000081954
haus1
HAUS augmin-like complex, subunit 1
chr11_-_12744413 0.46 ENSDART00000104143
txlng
taxilin gamma
KN149830v1_-_31870 0.46 ENSDART00000167653
zgc:194336
zgc:194336
chr23_-_29467861 0.46 ENSDART00000017728
pgd
phosphogluconate dehydrogenase
chr20_+_24047842 0.45 ENSDART00000128616
ENSDART00000144195
casp8ap2
caspase 8 associated protein 2
chr3_+_52290252 0.45 ENSDART00000018908
slc27a1a
solute carrier family 27 (fatty acid transporter), member 1a
chr3_-_34208507 0.45 ENSDART00000151634
tnrc6c1
trinucleotide repeat containing 6C1
chr15_-_47260834 0.45 ENSDART00000098711
eif3k
eukaryotic translation initiation factor 3, subunit K
chr2_+_11335970 0.45 ENSDART00000055737
tyw3
tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
chr17_-_8155740 0.44 ENSDART00000064678
lft2
lefty2
chr16_-_31664756 0.44 ENSDART00000176939
phf20l1
PHD finger protein 20-like 1
chr5_-_68848113 0.44 ENSDART00000097249
aldh2.2
aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 2
chr19_+_5562075 0.44 ENSDART00000148794
jupb
junction plakoglobin b
chr12_+_22459371 0.44 ENSDART00000171725
capgb
capping protein (actin filament), gelsolin-like b
chr8_-_22305457 0.43 ENSDART00000149517
cep104
centrosomal protein 104
chr8_+_21127033 0.43 ENSDART00000033491
spryd4
SPRY domain containing 4
chr22_-_35218207 0.43 ENSDART00000104687
pfn2
profilin 2
chr11_+_30006715 0.43 ENSDART00000157272
ENSDART00000003475
ppef1
protein phosphatase, EF-hand calcium binding domain 1
chr20_+_54404819 0.43 ENSDART00000099338
actr10
ARP10 actin related protein 10 homolog
chr9_+_2523927 0.43 ENSDART00000166326
si:ch73-167c12.2
si:ch73-167c12.2
chr11_-_2437361 0.42

chr10_-_43874646 0.42 ENSDART00000025366
cetn3
centrin 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0090656 t-circle formation(GO:0090656)
0.5 1.4 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.4 1.7 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.3 1.0 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.3 1.6 GO:0032289 central nervous system myelin formation(GO:0032289)
0.3 0.8 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.2 0.7 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.2 1.4 GO:0030237 female sex determination(GO:0030237)
0.2 0.7 GO:0070655 mechanosensory epithelium regeneration(GO:0070655) mechanoreceptor differentiation involved in mechanosensory epithelium regeneration(GO:0070656) neuromast regeneration(GO:0070657) neuromast hair cell differentiation involved in neuromast regeneration(GO:0070658)
0.2 2.8 GO:0050796 regulation of insulin secretion(GO:0050796)
0.2 0.8 GO:0070986 left/right axis specification(GO:0070986)
0.2 0.8 GO:1903726 negative regulation of phospholipid metabolic process(GO:1903726)
0.2 0.9 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.2 0.5 GO:2000623 negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 0.7 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 2.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 1.3 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.2 2.3 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 0.7 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.1 1.6 GO:0006465 signal peptide processing(GO:0006465)
0.1 2.2 GO:0060046 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.5 GO:0051977 lysophospholipid transport(GO:0051977) lipid transport across blood brain barrier(GO:1990379)
0.1 0.6 GO:2001287 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 1.7 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 0.3 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.1 0.5 GO:0000012 single strand break repair(GO:0000012)
0.1 0.5 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 0.3 GO:0042373 vitamin K metabolic process(GO:0042373) cellular response to fluid shear stress(GO:0071498)
0.1 0.5 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 4.0 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.1 0.4 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 1.8 GO:0051014 actin filament severing(GO:0051014)
0.1 1.0 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.2 GO:0006531 aspartate metabolic process(GO:0006531)
0.1 0.2 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 0.2 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 0.6 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 1.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 2.1 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.7 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.5 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 1.8 GO:0001878 response to yeast(GO:0001878)
0.0 1.3 GO:0051607 defense response to virus(GO:0051607)
0.0 0.9 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 1.1 GO:0042493 response to drug(GO:0042493)
0.0 0.5 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.6 GO:0016233 telomere capping(GO:0016233)
0.0 0.7 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.2 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.4 GO:0006183 GTP biosynthetic process(GO:0006183)
0.0 1.3 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.6 GO:0006298 mismatch repair(GO:0006298)
0.0 0.4 GO:0003128 heart field specification(GO:0003128)
0.0 0.5 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 1.0 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.4 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 1.5 GO:0072329 monocarboxylic acid catabolic process(GO:0072329)
0.0 0.3 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.4 GO:0050906 detection of stimulus involved in sensory perception(GO:0050906)
0.0 0.2 GO:1901909 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.5 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.3 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 1.2 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.4 GO:0002429 immune response-activating cell surface receptor signaling pathway(GO:0002429)
0.0 0.1 GO:0030814 regulation of cAMP metabolic process(GO:0030814) regulation of cAMP biosynthetic process(GO:0030817) regulation of adenylate cyclase activity(GO:0045761)
0.0 0.4 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.2 GO:0034311 diol metabolic process(GO:0034311)
0.0 0.3 GO:0031297 replication fork processing(GO:0031297)
0.0 0.8 GO:0022406 membrane docking(GO:0022406)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.8 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.3 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone metabolic process(GO:1901661) quinone biosynthetic process(GO:1901663)
0.0 0.5 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.6 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.2 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.3 2.8 GO:0030667 secretory granule membrane(GO:0030667)
0.2 1.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 1.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.2 0.6 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.2 2.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 1.6 GO:0005869 dynactin complex(GO:0005869)
0.1 1.0 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.6 GO:0070187 telosome(GO:0070187)
0.1 0.2 GO:0097196 Shu complex(GO:0097196)
0.1 0.4 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 2.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.3 GO:0000811 GINS complex(GO:0000811)
0.1 0.2 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 0.6 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.5 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.0 0.3 GO:0035101 FACT complex(GO:0035101)
0.0 1.3 GO:0005902 microvillus(GO:0005902)
0.0 0.3 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.5 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 1.8 GO:0001726 ruffle(GO:0001726)
0.0 0.4 GO:0044545 NSL complex(GO:0044545)
0.0 0.4 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 2.0 GO:0000786 nucleosome(GO:0000786)
0.0 0.6 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.3 GO:0043296 apical junction complex(GO:0043296)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 1.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.8 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.4 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0017119 Golgi transport complex(GO:0017119)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.5 2.1 GO:1903231 mRNA binding involved in posttranscriptional gene silencing(GO:1903231)
0.5 1.4 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.4 1.2 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.4 2.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.3 1.0 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.3 1.7 GO:0034338 short-chain carboxylesterase activity(GO:0034338)
0.3 1.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 2.2 GO:0035804 structural constituent of egg coat(GO:0035804)
0.2 0.7 GO:0004348 glucosylceramidase activity(GO:0004348)
0.2 1.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 1.4 GO:0070698 type I activin receptor binding(GO:0070698)
0.2 2.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 1.6 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 1.0 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 1.0 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2 1.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.6 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.1 2.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.5 GO:0051978 lysophospholipid transporter activity(GO:0051978)
0.1 2.0 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.9 GO:0008143 poly(A) binding(GO:0008143)
0.1 3.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.6 GO:0015562 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) efflux transmembrane transporter activity(GO:0015562)
0.1 0.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 3.2 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.1 1.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.5 GO:0090624 endoribonuclease activity, cleaving miRNA-paired mRNA(GO:0090624)
0.1 0.3 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.5 GO:0005537 mannose binding(GO:0005537)
0.1 0.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.4 GO:0016972 flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
0.1 0.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.3 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 0.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.4 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.3 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 1.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.8 GO:0044325 ion channel binding(GO:0044325)
0.0 1.2 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 2.8 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.2 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.4 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 2.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.5 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.6 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 1.3 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 2.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.4 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.5 GO:0050661 NADP binding(GO:0050661)
0.0 0.5 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.7 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.2 GO:0031267 small GTPase binding(GO:0031267)
0.0 3.4 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 4.9 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.7 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.9 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.6 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.4 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 1.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 0.7 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 1.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair