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Results for pax8

Z-value: 0.27

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Transcription factors associated with pax8

Gene Symbol Gene ID Gene Info
pax8
ENSDARG00000015879 paired box 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pax8dr10_dc_chr5_-_71643185_71643209-0.591.7e-02Click!

Activity profile of pax8 motif

Sorted Z-values of pax8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of pax8

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr24_-_25297360 0.46 ENSDART00000138215
phex
phosphate regulating endopeptidase homolog, X-linked
chr16_-_34240818 0.40 ENSDART00000054026
rcc1
regulator of chromosome condensation 1
chr4_+_1727494 0.34 ENSDART00000149448
AL929171.1
ENSDARG00000095920
chr9_+_35205519 0.32 ENSDART00000100700
gabpa
GA binding protein transcription factor, alpha subunit
chr5_-_36741099 0.29 ENSDART00000084675
wdr44
WD repeat domain 44
chr9_-_23954640 0.26 ENSDART00000027212
ENSDARG00000006848
ENSDARG00000006848
chr5_-_36741219 0.26 ENSDART00000084675
wdr44
WD repeat domain 44
chr5_-_36741034 0.25 ENSDART00000084675
wdr44
WD repeat domain 44
chr23_-_24772871 0.25 ENSDART00000104031
sdf4
stromal cell derived factor 4
chr16_-_43107682 0.24 ENSDART00000142003
nudt17
nudix (nucleoside diphosphate linked moiety X)-type motif 17
chr10_+_29883772 0.24 ENSDART00000100032
hyou1
hypoxia up-regulated 1
chr12_-_4212149 0.24 ENSDART00000059298
zgc:92313
zgc:92313
chr19_-_2084484 0.22

chr24_-_25297298 0.21 ENSDART00000138215
phex
phosphate regulating endopeptidase homolog, X-linked
chr12_+_19226572 0.21 ENSDART00000066388
tomm22
translocase of outer mitochondrial membrane 22 homolog (yeast)
chr10_+_29884057 0.20 ENSDART00000100032
hyou1
hypoxia up-regulated 1
chr7_-_29084775 0.20 ENSDART00000075757
gtf2a2
general transcription factor IIA, 2
chr7_+_19300487 0.19 ENSDART00000169060
si:ch211-212k18.5
si:ch211-212k18.5
chr9_-_22014861 0.19 ENSDART00000101986
mrpl30
mitochondrial ribosomal protein L30
chr4_+_56996802 0.19

chr9_+_2538387 0.19

chr9_-_23954761 0.18 ENSDART00000027212
ENSDARG00000006848
ENSDARG00000006848
chr13_+_32323781 0.18 ENSDART00000057421
rdh14a
retinol dehydrogenase 14a (all-trans/9-cis/11-cis)
chr9_-_32532691 0.17 ENSDART00000078499
rftn2
raftlin family member 2
chr21_-_20083822 0.17 ENSDART00000065664
dusp4
dual specificity phosphatase 4
chr11_-_40239946 0.17 ENSDART00000165394
si:dkeyp-61b2.1
si:dkeyp-61b2.1
chr13_-_35719176 0.16 ENSDART00000171371
map3k4
mitogen-activated protein kinase kinase kinase 4
chr16_+_46728897 0.14 ENSDART00000169767
rab25b
RAB25, member RAS oncogene family b
chr9_-_23954690 0.14 ENSDART00000027212
ENSDARG00000006848
ENSDARG00000006848
chr4_+_90885 0.14 ENSDART00000169805
eps8
epidermal growth factor receptor pathway substrate 8
chr6_-_50588444 0.13 ENSDART00000151500
mtss1
metastasis suppressor 1
chr9_+_35205252 0.13 ENSDART00000100701
gabpa
GA binding protein transcription factor, alpha subunit
chr22_+_3994627 0.13 ENSDART00000166768
timm44
translocase of inner mitochondrial membrane 44 homolog (yeast)
chr20_+_15264912 0.12 ENSDART00000063877
prdx6
peroxiredoxin 6
chr12_-_4212095 0.12 ENSDART00000059298
zgc:92313
zgc:92313
chr11_-_25224150 0.11 ENSDART00000014945
hcfc1a
host cell factor C1a
chr11_+_18856937 0.11

chr12_+_23300259 0.11

chr8_-_7278846 0.11 ENSDART00000162228
grip2a
glutamate receptor interacting protein 2a
chr16_+_50355723 0.11 ENSDART00000166664
ENSDARG00000102916
ENSDARG00000102916
chr12_+_19226616 0.10 ENSDART00000066388
tomm22
translocase of outer mitochondrial membrane 22 homolog (yeast)
chr22_-_16128314 0.10 ENSDART00000009464
slc30a7
solute carrier family 30 (zinc transporter), member 7
chr9_+_23954807 0.10 ENSDART00000145120
ENSDARG00000040445
ENSDARG00000040445
chr10_+_24690784 0.10 ENSDART00000147974
vps36
vacuolar protein sorting 36 homolog (S. cerevisiae)
chr24_+_31396974 0.09 ENSDART00000168837
fam168b
family with sequence similarity 168, member B
chr19_-_2084281 0.08

chr20_-_14784875 0.08 ENSDART00000063857
scrn2
secernin 2
chr9_+_23954669 0.08 ENSDART00000145120
ENSDARG00000040445
ENSDARG00000040445
chr15_+_16451221 0.08 ENSDART00000101157
flot2b
flotillin 2b
chr9_-_32532616 0.07 ENSDART00000078499
rftn2
raftlin family member 2
chr3_-_15960288 0.06 ENSDART00000051807
lasp1
LIM and SH3 protein 1
chr17_+_612173 0.06

chr23_-_24772748 0.05 ENSDART00000104031
sdf4
stromal cell derived factor 4
chr22_+_18904372 0.04 ENSDART00000131131
bsg
basigin
chr9_+_23954607 0.04 ENSDART00000145120
ENSDARG00000040445
ENSDARG00000040445
chr5_+_68055581 0.04 ENSDART00000061406
usp39
ubiquitin specific peptidase 39
chr9_-_22014768 0.04 ENSDART00000101986
mrpl30
mitochondrial ribosomal protein L30
chr6_-_47841704 0.04 ENSDART00000141986
lrig2
leucine-rich repeats and immunoglobulin-like domains 2
chr23_-_24772650 0.03 ENSDART00000104031
sdf4
stromal cell derived factor 4
chr25_+_18378608 0.03 ENSDART00000158142
ENSDART00000073563
tes
testis derived transcript (3 LIM domains)
chr5_+_68055760 0.02 ENSDART00000061406
usp39
ubiquitin specific peptidase 39
chr10_+_24690680 0.02 ENSDART00000147974
vps36
vacuolar protein sorting 36 homolog (S. cerevisiae)
chr24_-_21828216 0.02 ENSDART00000030592
acot9.1
acyl-CoA thioesterase 9, tandem duplicate 1
chr13_-_35719075 0.02 ENSDART00000171371
map3k4
mitogen-activated protein kinase kinase kinase 4
KN149962v1_-_109672 0.02

chr23_-_7191380 0.02 ENSDART00000176914
slco4a1
solute carrier organic anion transporter family, member 4A1
chr7_-_28278230 0.01 ENSDART00000054368
st5
suppression of tumorigenicity 5
chr7_-_51210658 0.01 ENSDART00000174026
nhsl2
NHS-like 2
chr10_+_36094175 0.01 ENSDART00000164678
katnal1
katanin p60 subunit A-like 1
chr20_+_32321484 0.01 ENSDART00000147448
sesn1
sestrin 1
chr18_+_27242463 0.01

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.1 0.2 GO:0019677 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.0 0.4 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.2 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.1 GO:0048855 hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852) adenohypophysis morphogenesis(GO:0048855)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.2 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated