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Results for pax9_pax1a+pax1b

Z-value: 0.86

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Transcription factors associated with pax9_pax1a+pax1b

Gene Symbol Gene ID Gene Info
pax9
ENSDARG00000053829 paired box 9
pax1a
ENSDARG00000008203 paired box 1a
pax1b
ENSDARG00000073814 paired box 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pax9dr10_dc_chr17_-_38296557_382965710.656.7e-03Click!

Activity profile of pax9_pax1a+pax1b motif

Sorted Z-values of pax9_pax1a+pax1b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of pax9_pax1a+pax1b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr24_+_41790437 4.44 ENSDART00000159135
ENSDART00000158456
ENSDART00000160069
lama1
laminin, alpha 1
chr18_+_48426375 3.26

chr21_+_13764828 2.81 ENSDART00000171306
stxbp1a
syntaxin binding protein 1a
chr15_+_41878670 2.58 ENSDART00000137434
pxylp1
2-phosphoxylose phosphatase 1
chr2_-_44429891 2.46 ENSDART00000163040
ENSDART00000056372
ENSDART00000109251
ENSDART00000166923
ENSDART00000132682
mpz
myelin protein zero
chr23_+_157661 2.18

chr5_+_296856 1.83

chr21_+_13764917 1.76 ENSDART00000015629
stxbp1a
syntaxin binding protein 1a
chr4_-_16461748 1.71 ENSDART00000128835
wu:fc23c09
wu:fc23c09
chr12_+_10594531 1.68

chr18_-_3244618 1.61 ENSDART00000161520
gdpd4a
glycerophosphodiester phosphodiesterase domain containing 4a
chr16_-_9108885 1.54 ENSDART00000153785
triob
trio Rho guanine nucleotide exchange factor b
chr1_+_38834751 1.32 ENSDART00000137676
tenm3
teneurin transmembrane protein 3
chr17_+_1610578 1.24 ENSDART00000082101
ppp2r5ca
protein phosphatase 2, regulatory subunit B', gamma a
chr12_-_7820226 1.21 ENSDART00000149594
ENSDART00000148866
ank3b
ankyrin 3b
chr17_+_794430 1.06 ENSDART00000158830
cyp1c2
cytochrome P450, family 1, subfamily C, polypeptide 2
chr20_+_29685096 0.92 ENSDART00000153339
adam17b
ADAM metallopeptidase domain 17b
chr5_+_52198613 0.80 ENSDART00000162459
scarb2a
scavenger receptor class B, member 2a
chr10_+_39211384 0.76

chr9_-_24219908 0.73 ENSDART00000144163
rpe
ribulose-5-phosphate-3-epimerase
chr16_+_20932876 0.71 ENSDART00000079343
jazf1b
JAZF zinc finger 1b
chr13_-_24248675 0.68 ENSDART00000046360
rhoua
ras homolog family member Ua
chr14_+_23220869 0.67 ENSDART00000112930
si:ch211-221f10.2
si:ch211-221f10.2
chr10_-_39211281 0.66 ENSDART00000148825
slc37a4b
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr5_-_35143549 0.65 ENSDART00000157881
ophn1
oligophrenin 1
chr3_-_49242655 0.65 ENSDART00000142200
ENSDART00000139524
arl16
ADP-ribosylation factor-like 16
chr24_-_36840203 0.44 ENSDART00000135142
si:ch73-334d15.1
si:ch73-334d15.1
chr6_-_26897413 0.31

chr8_-_16614882 0.30 ENSDART00000135319
osbpl9
oxysterol binding protein-like 9
chr20_+_29685331 0.30 ENSDART00000153339
adam17b
ADAM metallopeptidase domain 17b
chr9_-_23177842 0.19

chr23_+_46015863 0.16 ENSDART00000012234
syap1
synapse associated protein 1
chr8_+_48976926 0.05 ENSDART00000008058
aak1a
AP2 associated kinase 1a
chr24_+_3447129 0.02 ENSDART00000134598
wdr37
WD repeat domain 37
chr20_+_12809388 0.01 ENSDART00000163499
zgc:153383
zgc:153383
chr7_+_26274252 0.00 ENSDART00000164824
tnk1
tyrosine kinase, non-receptor, 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.7 4.4 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.4 1.3 GO:1903385 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.2 0.7 GO:0019323 pentose catabolic process(GO:0019323)
0.1 4.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.8 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 1.2 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 0.7 GO:0032488 Cdc42 protein signal transduction(GO:0032488)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 GO:0043209 myelin sheath(GO:0043209)
0.1 4.4 GO:0005604 basement membrane(GO:0005604)
0.1 4.6 GO:0030141 secretory granule(GO:0030141)
0.0 1.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 4.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.2 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 0.7 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 1.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.6 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.3 GO:0015248 sterol transporter activity(GO:0015248)
0.0 1.3 GO:0042803 protein homodimerization activity(GO:0042803)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.7 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions