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Results for pbx4

Z-value: 1.14

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Transcription factors associated with pbx4

Gene Symbol Gene ID Gene Info
pbx4
ENSDARG00000052150 pre-B-cell leukemia transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pbx4dr10_dc_chr3_+_52745606_52745690-0.852.5e-05Click!

Activity profile of pbx4 motif

Sorted Z-values of pbx4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of pbx4

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr7_-_25426346 8.35 ENSDART00000082620
dysf
dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
chr21_-_23271127 5.00 ENSDART00000007806
zbtb16a
zinc finger and BTB domain containing 16a
chr13_-_5440923 4.63 ENSDART00000102576
meis1b
Meis homeobox 1 b
chr19_+_25009921 3.59

chr17_+_52736192 3.37 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr24_-_6868340 2.72 ENSDART00000158646
dpp6a
dipeptidyl-peptidase 6a
chr23_+_32573474 2.37 ENSDART00000134811
si:dkey-261h17.1
si:dkey-261h17.1
chr6_-_14821305 2.25

chr1_+_25378105 2.20 ENSDART00000059264
mxd4
MAX dimerization protein 4
chr25_+_24520476 2.17

chr19_-_5429428 2.15 ENSDART00000066620
ENSDART00000151398
krtt1c19e
keratin type 1 c19e
chr24_+_18804086 2.10 ENSDART00000106186
prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr20_-_42805703 2.08 ENSDART00000045816
plg
plasminogen
chr19_+_20209561 2.07 ENSDART00000168833
CR382300.1
ENSDARG00000098798
chr5_+_34857986 2.03 ENSDART00000141239
erlin2
ER lipid raft associated 2
chr7_+_26357875 1.97 ENSDART00000101044
hsbp1a
heat shock factor binding protein 1a
chr3_-_32202533 1.94 ENSDART00000155757
si:dkey-16p21.8
si:dkey-16p21.8
chr16_-_44682957 1.87

chr1_-_46292847 1.85 ENSDART00000125032
pknox1.2
pbx/knotted 1 homeobox 1.2
chr23_+_2391223 1.84

chr1_-_9387290 1.78 ENSDART00000135522
ENSDART00000135676
fga
fibrinogen alpha chain
chr17_-_52735250 1.77

chr6_+_29800606 1.74 ENSDART00000017424
ptmaa
prothymosin, alpha a
chr8_-_25055333 1.69 ENSDART00000134190
sort1b
sortilin 1b
chr21_-_43083936 1.67 ENSDART00000040169
jakmip2
janus kinase and microtubule interacting protein 2
chr8_+_49789789 1.67 ENSDART00000083790
ntrk2a
neurotrophic tyrosine kinase, receptor, type 2a
chr7_+_16610457 1.66

chr4_+_13811932 1.60 ENSDART00000067168
pdzrn4
PDZ domain containing ring finger 4
chr12_+_48643983 1.58 ENSDART00000168441
zgc:165653
zgc:165653
chr9_-_13383818 1.58 ENSDART00000084055
fzd7a
frizzled class receptor 7a
chr13_-_24316940 1.57 ENSDART00000127741
slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr3_-_45779817 1.57 ENSDART00000164361
gcgra
glucagon receptor a
chr23_+_20936419 1.49 ENSDART00000129992
pax7b
paired box 7b
chr12_-_26760324 1.48 ENSDART00000047724
zeb1b
zinc finger E-box binding homeobox 1b
chr17_-_52735615 1.47

chr22_-_5652624 1.46 ENSDART00000127688
ENSDART00000012686
dnase1l4.1
deoxyribonuclease 1 like 4, tandem duplicate 1
chr24_-_6048914 1.42 ENSDART00000146830
ENSDART00000021981
apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr5_-_20310793 1.38 ENSDART00000147639
si:ch211-225b11.1
si:ch211-225b11.1
chr13_-_5440751 1.36 ENSDART00000102576
meis1b
Meis homeobox 1 b
chr6_+_4712785 1.36 ENSDART00000151674
pcdh9
protocadherin 9
chr16_-_16433191 1.35 ENSDART00000022685
nradd
neurotrophin receptor associated death domain
chr9_-_23406315 1.34 ENSDART00000159256
kif5c
kinesin family member 5C
chr21_-_17259886 1.34 ENSDART00000114877
gfi1b
growth factor independent 1B transcription repressor
chr10_+_2779947 1.34 ENSDART00000131435
aebp1
AE binding protein 1
chr17_+_23892232 1.34

chr13_+_16130123 1.33 ENSDART00000170855
mocos
molybdenum cofactor sulfurase
chr16_-_54638972 1.33

chr4_-_13996902 1.31 ENSDART00000147955
prickle1b
prickle homolog 1b
chr18_+_48426375 1.30

chr2_-_21960233 1.29 ENSDART00000027587
ralab
v-ral simian leukemia viral oncogene homolog Ab (ras related)
chr5_+_49103778 1.29 ENSDART00000155405
CR751602.2
ENSDARG00000098045
chr23_-_15381030 1.29

chr23_+_20936374 1.26 ENSDART00000129992
pax7b
paired box 7b
chr8_+_47909655 1.24

chr13_-_31165867 1.24 ENSDART00000030946
prdm8
PR domain containing 8
chr5_+_296856 1.23

chr2_-_10394639 1.20 ENSDART00000128535
dmbx1a
diencephalon/mesencephalon homeobox 1a
chr23_-_15442032 1.20 ENSDART00000082060
ENSDARG00000078145
ENSDARG00000078145
chr3_-_15918262 1.20 ENSDART00000157315
ENSDARG00000097322
ENSDARG00000097322
chr13_-_5440558 1.17 ENSDART00000102576
meis1b
Meis homeobox 1 b
chr3_-_37558102 1.17 ENSDART00000151810
gpatch8
G patch domain containing 8
chr10_-_44509732 1.16

chr9_-_33916709 1.16 ENSDART00000028225
mao
monoamine oxidase
chr8_+_5222065 1.15 ENSDART00000035676
bnip3la
BCL2/adenovirus E1B interacting protein 3-like a
chr10_+_44509370 1.14

chr7_-_18346474 1.14

chr12_+_2835894 1.14 ENSDART00000165225
prkar1ab
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b
chr9_+_32267615 1.11

chr1_-_25377787 1.11

chr10_-_26782374 1.11 ENSDART00000162710
fgf13b
fibroblast growth factor 13b
chr20_-_29148810 1.10 ENSDART00000140350
thbs1b
thrombospondin 1b
chr9_-_2588401 1.10 ENSDART00000161018
sp9
sp9 transcription factor
chr8_+_30491476 1.09 ENSDART00000062073
ENSDARG00000042329
ENSDARG00000042329
chr21_+_22386643 1.09 ENSDART00000133190
capslb
calcyphosine-like b
chr16_-_19154920 1.09 ENSDART00000088818
fhod3b
formin homology 2 domain containing 3b
chr6_+_30441419 1.08

chr20_+_15119519 1.07 ENSDART00000039345
myoc
myocilin
chr11_+_43559400 1.07

chr10_+_45499009 1.04 ENSDART00000166085
ppiab
peptidylprolyl isomerase Ab (cyclophilin A)
chr10_+_9134634 1.03 ENSDART00000110443
fstb
follistatin b
chr2_-_1752776 1.03 ENSDART00000126566
slc22a23
solute carrier family 22, member 23
chr16_+_21121428 1.02

chr10_-_35293024 1.01 ENSDART00000145804
ypel2a
yippee-like 2a
chr5_+_44407763 1.01 ENSDART00000010786
dmrt2a
doublesex and mab-3 related transcription factor 2a
chr19_-_7576069 1.00 ENSDART00000148836
rfx5
regulatory factor X, 5
chr23_+_24711233 0.97

chr22_-_11408859 0.97 ENSDART00000007649
mid1ip1b
MID1 interacting protein 1b
chr18_+_5707066 0.96

chr7_+_56375651 0.96 ENSDART00000112242
zgc:194679
zgc:194679
chr20_+_15119754 0.96 ENSDART00000039345
myoc
myocilin
chr3_-_47328771 0.95 ENSDART00000020168
kctd5a
potassium channel tetramerization domain containing 5a
chr16_+_46902372 0.95 ENSDART00000177679
thsd7ab
thrombospondin, type I, domain containing 7Ab
chr13_-_31304614 0.95

chr15_+_32410860 0.93 ENSDART00000154457
fhdc4
FH2 domain containing 4
chr1_-_7744605 0.92 ENSDART00000033917
syngr3b
synaptogyrin 3b
chr4_-_16344954 0.90 ENSDART00000079523
epyc
epiphycan
chr24_+_35899507 0.89 ENSDART00000122408
si:dkeyp-7a3.1
si:dkeyp-7a3.1
chr6_-_2294751 0.89 ENSDART00000165223
pbx1b
pre-B-cell leukemia homeobox 1b
chr17_+_52736535 0.89 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr17_-_19606453 0.86 ENSDART00000011432
reep3a
receptor accessory protein 3a
chr12_-_11419332 0.86 ENSDART00000012318
htra1b
HtrA serine peptidase 1b
chr17_+_23102259 0.86 ENSDART00000178403
rasgrp3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr5_+_19737802 0.85 ENSDART00000153643
ssh1a
slingshot protein phosphatase 1a
chr3_-_16077831 0.84 ENSDART00000111707
cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr16_-_16244210 0.83 ENSDART00000012718
fabp11b
fatty acid binding protein 11b
chr16_-_50024848 0.83 ENSDART00000161782
etfb
electron-transfer-flavoprotein, beta polypeptide
chr6_-_50705420 0.82 ENSDART00000074100
osgn1
oxidative stress induced growth inhibitor 1
chr22_+_528076 0.82

chr3_+_23621843 0.82 ENSDART00000146636
hoxb2a
homeobox B2a
chr19_-_27284726 0.80 ENSDART00000089699
prrt1
proline-rich transmembrane protein 1
chr21_-_37914590 0.80

chr18_-_25002972 0.79 ENSDART00000163449
chd2
chromodomain helicase DNA binding protein 2
chr1_+_48708504 0.78 ENSDART00000008468
msx1b
muscle segment homeobox 1b
chr12_-_48643687 0.78 ENSDART00000178135
ENSDART00000176040
CABZ01078412.1
ENSDARG00000107260
chr2_-_1753058 0.78 ENSDART00000126566
slc22a23
solute carrier family 22, member 23
chr7_+_42124857 0.77 ENSDART00000004120
adamts18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr20_+_48971948 0.76 ENSDART00000164006
nkx2.4b
NK2 homeobox 4b
chr3_-_44113070 0.75 ENSDART00000160717
znf750
zinc finger protein 750
chr4_-_20764499 0.74 ENSDART00000023337
napepld
N-acyl phosphatidylethanolamine phospholipase D
chr8_+_8056616 0.74

chr15_+_3296905 0.73 ENSDART00000171723
foxo1a
forkhead box O1 a
chr5_-_33156615 0.73 ENSDART00000159058
dab2ipb
DAB2 interacting protein b
chr10_-_27780050 0.73 ENSDART00000138149
si:dkey-33o22.1
si:dkey-33o22.1
chr21_-_44109455 0.72 ENSDART00000044599
oatx
organic anion transporter X
chr18_-_45892 0.72 ENSDART00000052641
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr22_+_35090105 0.72

chr20_+_18803167 0.72 ENSDART00000019476
eif5
eukaryotic translation initiation factor 5
chr21_+_26690161 0.71 ENSDART00000065392
calm3b
calmodulin 3b (phosphorylase kinase, delta)
chr17_+_52736844 0.71 ENSDART00000160507
meis2a
Meis homeobox 2a
chr19_+_27133834 0.71 ENSDART00000134455
zgc:100906
zgc:100906
chr13_+_28286826 0.70 ENSDART00000043658
slc2a15a
solute carrier family 2 (facilitated glucose transporter), member 15a
chr5_-_24365811 0.70 ENSDART00000112287
gas2l1
growth arrest-specific 2 like 1
chr2_-_24947660 0.70 ENSDART00000113356
ENSDART00000163038
crtc1a
CREB regulated transcription coactivator 1a
chr21_-_36886505 0.70 ENSDART00000113678
wwc1
WW and C2 domain containing 1
chr4_+_9535985 0.69 ENSDART00000130083
lsm8
LSM8 homolog, U6 small nuclear RNA associated
chr1_-_56233548 0.68 ENSDART00000152597
si:ch211-1f22.1
si:ch211-1f22.1
chr15_+_895792 0.67

chr7_+_15619409 0.66 ENSDART00000144765
ENSDART00000145946
pax6b
paired box 6b
chr24_+_34227202 0.66 ENSDART00000105572
gbx1
gastrulation brain homeobox 1
chr14_-_205130 0.65 ENSDART00000035581
ENSDART00000158725
ENSDART00000163549
OTOP1
otopetrin 1
chr1_-_20132900 0.65 ENSDART00000054472
tll1
tolloid-like 1
chr22_+_35113233 0.64 ENSDART00000123066
srfa
serum response factor a
chr8_+_50994889 0.63 ENSDART00000142061
si:dkey-32e23.4
si:dkey-32e23.4
chr10_-_17383380 0.63

chr3_+_22447812 0.60 ENSDART00000112270
tanc2a
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2a
chr2_-_7560202 0.60 ENSDART00000164494
asip2b
agouti signaling protein, nonagouti homolog (mouse) 2b
chr6_+_40664212 0.59 ENSDART00000103842
eno1b
enolase 1b, (alpha)
chr3_+_23621561 0.58 ENSDART00000146636
hoxb2a
homeobox B2a
chr9_+_32267297 0.57

chr20_+_33889082 0.57 ENSDART00000175023
olfml2ba
olfactomedin-like 2Ba
chr9_+_56507484 0.56 ENSDART00000160980
sept10
septin 10
chr3_-_15556928 0.55 ENSDART00000134729
BX936308.1
ENSDARG00000081299
chr1_-_39509011 0.55 ENSDART00000146680
ENSDARG00000078251
ENSDARG00000078251
chr7_+_15623685 0.53 ENSDART00000146704
pax6b
paired box 6b
chr13_+_50062513 0.53 ENSDART00000124142
ENSDART00000099537
cox5b2
cytochrome c oxidase subunit Vb 2
chr16_+_54001592 0.52

chr11_-_16067646 0.52

chr5_-_19691538 0.52 ENSDART00000139675
dao.1
D-amino-acid oxidase, tandem duplicate 1
chr2_-_19181629 0.51 ENSDART00000165782
pbx1a
pre-B-cell leukemia homeobox 1a
chr5_-_24365560 0.51 ENSDART00000112287
gas2l1
growth arrest-specific 2 like 1
chr16_+_35917621 0.50

chr10_-_17383466 0.47

chr4_-_16344835 0.47 ENSDART00000134449
epyc
epiphycan
chr5_-_48377307 0.47 ENSDART00000097452
si:dkey-172m14.1
si:dkey-172m14.1
chr18_+_20836320 0.47 ENSDART00000090100
ttc23
tetratricopeptide repeat domain 23
chr19_+_14197118 0.47 ENSDART00000166230
tpbga
trophoblast glycoprotein a
chr19_-_24683045 0.45 ENSDART00000104083
s100v2
S100 calcium binding protein V2
chr12_+_34726748 0.45 ENSDART00000105533
enthd2
ENTH domain containing 2
chr20_-_54591757 0.45 ENSDART00000136779
entpd5b
ectonucleoside triphosphate diphosphohydrolase 5b
chr12_+_47029281 0.44

chr16_-_36090863 0.44

chr14_-_1342450 0.44 ENSDART00000060417
cetn4
centrin 4
chr15_-_42081757 0.44 ENSDART00000004338
epha4l
eph receptor A4, like
chr2_-_54028761 0.44 ENSDART00000178289
CABZ01050256.1
ENSDARG00000109075
chr17_-_28084988 0.43 ENSDART00000149654
kdm1a
lysine (K)-specific demethylase 1a
chr23_+_20936600 0.43 ENSDART00000129992
pax7b
paired box 7b
chr2_-_52792076 0.42 ENSDART00000097716
zgc:136336
zgc:136336
chr22_+_17409030 0.41 ENSDART00000139523
rabgap1l
RAB GTPase activating protein 1-like
chr19_+_43524566 0.40 ENSDART00000129362
eef1a1l2
eukaryotic translation elongation factor 1 alpha 1, like 2
chr7_-_20201693 0.40 ENSDART00000174001
ntn5
netrin 5
chr7_-_20201358 0.39 ENSDART00000174001
ntn5
netrin 5
chr9_-_13383708 0.39 ENSDART00000084055
fzd7a
frizzled class receptor 7a
chr5_-_24365703 0.38 ENSDART00000112287
gas2l1
growth arrest-specific 2 like 1
chr8_-_12253026 0.38 ENSDART00000091612
dab2ipa
DAB2 interacting protein a
chr3_-_39117801 0.38 ENSDART00000102678
nmt1a
N-myristoyltransferase 1a
KN150015v1_+_1935 0.38 ENSDART00000169907
ENSDART00000160155
PDCL3
phosducin like 3
chr2_+_34155114 0.37 ENSDART00000137170
dars2
aspartyl-tRNA synthetase 2, mitochondrial
chr13_-_49749469 0.36 ENSDART00000136165
lyst
lysosomal trafficking regulator
chr20_+_4750766 0.35 ENSDART00000153486
lgals8a
galectin 8a
chr11_+_23012136 0.35 ENSDART00000110152
csf1a
colony stimulating factor 1a (macrophage)
chr10_-_14587464 0.35 ENSDART00000057865
ier3ip1
immediate early response 3 interacting protein 1
chr5_-_23715514 0.34 ENSDART00000011878
eif4a1b
eukaryotic translation initiation factor 4A1B
chr16_+_24047857 0.33

chr11_-_29569229 0.33 ENSDART00000069132
cybb
cytochrome b-245, beta polypeptide (chronic granulomatous disease)
chr16_-_19154824 0.31 ENSDART00000088818
fhod3b
formin homology 2 domain containing 3b
chr23_+_2391317 0.31

chr24_+_20391758 0.31 ENSDART00000082082
gars
glycyl-tRNA synthetase
chr23_-_18454945 0.30 ENSDART00000016891
hsd17b10
hydroxysteroid (17-beta) dehydrogenase 10
chr15_+_14925920 0.29

chr6_-_2294717 0.29 ENSDART00000165223
pbx1b
pre-B-cell leukemia homeobox 1b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.3 GO:0050765 monocyte activation involved in immune response(GO:0002280) negative regulation of phagocytosis(GO:0050765)
1.2 5.0 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.8 3.2 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.7 2.1 GO:0042730 fibrinolysis(GO:0042730)
0.7 2.0 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.6 1.7 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.5 1.5 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.4 7.2 GO:0072554 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.4 2.0 GO:0035988 chondrocyte proliferation(GO:0035988)
0.4 2.6 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.3 1.3 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971) axo-dendritic protein transport(GO:0099640)
0.2 0.7 GO:0070292 N-acylphosphatidylethanolamine metabolic process(GO:0070292)
0.2 0.7 GO:0048659 smooth muscle cell proliferation(GO:0048659) smooth muscle tissue development(GO:0048745)
0.2 0.7 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.2 1.2 GO:0090104 pancreatic epsilon cell differentiation(GO:0090104)
0.2 0.7 GO:0032475 otolith formation(GO:0032475)
0.2 1.3 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.2 1.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 1.7 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 0.6 GO:1903146 regulation of mitophagy(GO:1903146)
0.2 0.6 GO:0050886 negative regulation of lipid transport(GO:0032369) endocrine process(GO:0050886) positive regulation of feeding behavior(GO:2000253)
0.2 1.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.2 2.0 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.2 1.1 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.2 1.2 GO:0009712 catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712) neurotransmitter catabolic process(GO:0042135)
0.2 1.8 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 0.6 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 1.0 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 2.0 GO:0001952 regulation of cell-matrix adhesion(GO:0001952)
0.1 0.4 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 1.1 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.1 1.4 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.3 GO:0021754 facial nucleus development(GO:0021754)
0.1 0.5 GO:0019478 D-amino acid catabolic process(GO:0019478) D-serine catabolic process(GO:0036088) D-amino acid metabolic process(GO:0046416) D-serine metabolic process(GO:0070178)
0.1 0.7 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 0.4 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.1 0.3 GO:0042554 superoxide anion generation(GO:0042554)
0.1 1.9 GO:0006825 copper ion transport(GO:0006825)
0.1 1.3 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.1 1.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.9 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 1.2 GO:0061074 regulation of neural retina development(GO:0061074)
0.1 0.5 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.1 1.6 GO:0051764 actin crosslink formation(GO:0051764)
0.1 1.0 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.7 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.8 GO:0030878 thyroid gland development(GO:0030878)
0.1 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.2 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 0.8 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 0.2 GO:0090594 inflammatory response to wounding(GO:0090594)
0.1 0.5 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 1.9 GO:0060037 pharyngeal system development(GO:0060037)
0.0 5.7 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 1.6 GO:0010675 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.0 1.0 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 1.0 GO:0007548 sex differentiation(GO:0007548)
0.0 0.2 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.1 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.1 GO:0035143 embryonic caudal fin morphogenesis(GO:0035124) caudal fin morphogenesis(GO:0035143)
0.0 0.2 GO:0010165 response to X-ray(GO:0010165)
0.0 1.0 GO:0046890 regulation of lipid biosynthetic process(GO:0046890)
0.0 1.4 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.1 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.0 1.3 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 1.0 GO:0051260 protein homooligomerization(GO:0051260)
0.0 1.2 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 3.7 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 0.2 GO:0072102 glomerulus morphogenesis(GO:0072102)
0.0 0.9 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.8 GO:0016358 dendrite development(GO:0016358)
0.0 0.3 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.0 1.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.3 GO:0030315 T-tubule(GO:0030315)
0.6 1.8 GO:0005577 fibrinogen complex(GO:0005577)
0.3 1.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 2.6 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 2.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 0.9 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.9 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 1.4 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.1 GO:0030426 filopodium(GO:0030175) growth cone(GO:0030426)
0.0 0.1 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 2.2 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.6 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 1.9 GO:0030424 axon(GO:0030424)
0.0 2.6 GO:0005874 microtubule(GO:0005874)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.5 1.4 GO:0043121 neurotrophin binding(GO:0043121)
0.4 1.7 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.4 1.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.4 1.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.3 1.3 GO:0030151 molybdenum ion binding(GO:0030151)
0.3 2.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 1.3 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.2 1.9 GO:0016531 copper chaperone activity(GO:0016531)
0.2 8.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.6 GO:0017046 peptide hormone binding(GO:0017046)
0.1 0.7 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 2.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 12.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 1.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.0 GO:0048185 activin binding(GO:0048185)
0.1 0.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 5.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 1.0 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.5 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 1.0 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.7 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.5 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 1.3 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 1.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 3.0 GO:0015293 symporter activity(GO:0015293)
0.0 0.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 2.0 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 2.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.8 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 3.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 3.2 GO:0008017 microtubule binding(GO:0008017)
0.0 0.3 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 2.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.1 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.9 GO:0004222 metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 2.1 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 2.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 1.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.0 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.4 3.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 1.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC