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Results for pitx2

Z-value: 1.21

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Transcription factors associated with pitx2

Gene Symbol Gene ID Gene Info
ENSDARG00000036194 paired-like homeodomain 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pitx2dr10_dc_chr14_+_35885903_358859940.656.0e-03Click!

Activity profile of pitx2 motif

Sorted Z-values of pitx2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of pitx2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr18_-_46356213 2.81 ENSDART00000010813
forkhead box A3
chr17_+_1080921 2.78

chr15_+_35184996 2.35 ENSDART00000086954
ENSDART00000161594
sestrin 3
chr12_+_30591157 2.10 ENSDART00000133869
potassium channel, subfamily K, member 1a
chr6_+_29226868 1.97 ENSDART00000006386
ATPase, Na+/K+ transporting, beta 1a polypeptide
chr15_-_38027363 1.86 ENSDART00000157550
si:dkey-238d18.15
chr14_+_6117282 1.86 ENSDART00000051556
ATP-binding cassette, sub-family A (ABC1), member 1B
chr14_-_40454194 1.77 ENSDART00000166621
E74-like factor 1 (ets domain transcription factor)
chr15_-_25649570 1.75 ENSDART00000154733
si:dkey-54n8.2
chr16_+_46728964 1.65 ENSDART00000163571
RAB25, member RAS oncogene family b
chr8_-_31098193 1.59 ENSDART00000098925
vestigial like 4 like
chr14_-_5239605 1.59 ENSDART00000054877
fibroblast growth factor 24
chr3_-_10342940 1.53 ENSDART00000124419
ENSDARG00000101154
chr12_+_9504247 1.49 ENSDART00000127952
prolyl 4-hydroxylase, alpha polypeptide I a
chr8_+_17148864 1.39 ENSDART00000140531
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)
chr23_+_23305483 1.37 ENSDART00000126479
pleckstrin homology domain containing, family N member 1
chr11_+_5929544 1.30 ENSDART00000104364
ribosomal protein S15
chr19_+_17832515 1.29 ENSDART00000149045
Kruppel-like factor 2b
chr7_-_54407461 1.21 ENSDART00000162795
cyclin D1
chr11_+_6446302 1.11 ENSDART00000140707
ENSDART00000036939
growth arrest and DNA-damage-inducible, beta a
chr5_+_45822196 1.10

chr7_+_23843682 1.10 ENSDART00000173899
mitochondrial ribosomal protein L52
chr15_+_46114986 1.09 ENSDART00000156366
si:ch1073-340i21.3
chr17_-_25865861 1.09

chr16_-_45943282 1.05 ENSDART00000133213
antifreeze protein type IV
chr19_-_28699796 1.04 ENSDART00000079104
NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr23_+_18565721 1.03

chr15_-_643531 0.98 ENSDART00000102257
arachidonate 5-lipoxygenase b, tandem duplicate 3
chr16_-_17350056 0.97 ENSDART00000079497
EMG1 N1-specific pseudouridine methyltransferase
chr8_-_22486746 0.91 ENSDART00000101616
si:ch211-261n11.5
chr13_+_43266551 0.88 ENSDART00000084321
dishevelled-binding antagonist of beta-catenin 2
chr7_+_38455040 0.87

chr7_+_73598802 0.86 ENSDART00000109720
zgc:163061
chr2_+_25468904 0.86 ENSDART00000056801
male-specific lethal 2 homolog a (Drosophila)
chr25_+_21732255 0.83 ENSDART00000027393
creatine kinase, mitochondrial 1
chr5_+_63068121 0.83 ENSDART00000135097
si:ch73-274k23.1
chr19_-_15951003 0.82 ENSDART00000133059
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4a
KN149859v1_+_16751 0.82 ENSDART00000167610
ENSDARG00000103399
chr6_+_29226824 0.80 ENSDART00000006386
ATPase, Na+/K+ transporting, beta 1a polypeptide
chr18_-_44323435 0.79 ENSDART00000098599
si:ch211-151h10.2
chr5_+_58017820 0.78 ENSDART00000083015
coiled-coil domain containing 84
chr5_+_11340748 0.77 ENSDART00000159248
tescalcin a
chr7_+_37105966 0.75 ENSDART00000111842
spalt-like transcription factor 1a
chr20_-_32431934 0.73

chr8_+_21974863 0.69

chr21_+_13030816 0.68 ENSDART00000179221
outer dense fiber of sperm tails 2a
chr15_-_20088439 0.67 ENSDART00000161379
autism susceptibility candidate 2b
chr3_-_24550538 0.65 ENSDART00000161612
ENSDARG00000099678
chr10_-_43924675 0.65 ENSDART00000052307
arrestin domain containing 3b
chr10_+_17470158 0.61

chr25_-_17271237 0.60 ENSDART00000110692
cytochrome P450, family 2, subfamily X, polypeptide 6
chr23_+_8261065 0.60 ENSDART00000044733
neuropeptides B and W receptor 2
chr19_-_32214978 0.60 ENSDART00000103640
hes-related family bHLH transcription factor with YRPW motif 1
chr8_-_23591082 0.56 ENSDART00000025024
solute carrier family 38, member 5b
chr16_+_26989962 0.56 ENSDART00000140673
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1
chr11_-_4216204 0.56 ENSDART00000121716
ENSDARG00000086300
chr3_+_50398735 0.55

chr24_-_16995194 0.54 ENSDART00000111079
ENSDARG00000077318
chr21_+_13031158 0.54 ENSDART00000081426
outer dense fiber of sperm tails 2a
chr25_+_34515221 0.54 ENSDART00000046218
filamin C, gamma a (actin binding protein 280)
chr22_+_1296143 0.54 ENSDART00000170421
si:ch73-138e16.6
chr15_+_35185174 0.53 ENSDART00000086954
ENSDART00000161594
sestrin 3
chr6_+_24211657 0.53

chr4_-_29003925 0.51 ENSDART00000111294
zgc:174315
chr23_+_22649686 0.51 ENSDART00000146709
ENSDARG00000095377
chr16_-_25748690 0.51 ENSDART00000031304
derlin 1
chr23_+_9285446 0.49 ENSDART00000033663
ribosomal protein S21
chr8_+_17148832 0.49 ENSDART00000140531
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)
chr23_-_45927723 0.48

chr10_+_17470092 0.47

chr11_-_22211478 0.47 ENSDART00000065996
transmembrane protein 183A
chr23_-_17078246 0.46 ENSDART00000126841
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2
chr17_+_25503946 0.46

chr25_-_35817806 0.45 ENSDART00000129969
ENSDARG00000086604
chr2_+_3125365 0.45 ENSDART00000164308
ENSDART00000167649
phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
chr4_-_17226968 0.44 ENSDART00000177956
ENSDART00000177406
ENSDARG00000106175
chr19_+_44374082 0.44 ENSDART00000051712
GATA zinc finger domain containing 1
chr1_-_29958288 0.42 ENSDART00000085454
DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
chr16_+_25749018 0.39 ENSDART00000154024
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase
chr18_-_46355957 0.39 ENSDART00000010813
forkhead box A3
chr6_-_6160613 0.38

chr13_-_11873376 0.38 ENSDART00000111438
meningioma expressed antigen 5 (hyaluronidase)
chr21_-_40389601 0.38 ENSDART00000003221
nuclear speckle splicing regulatory protein 1
chr24_-_21114505 0.36 ENSDART00000111025
BOC cell adhesion associated, oncogene regulated
chr9_-_23936295 0.35 ENSDART00000165907
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10
chr25_-_34634503 0.35 ENSDART00000157370
Histone H3.2
chr23_+_23305376 0.34 ENSDART00000126479
pleckstrin homology domain containing, family N member 1
chr18_+_618393 0.34 ENSDART00000159464
neural precursor cell expressed, developmentally down-regulated 4a
chr23_-_18454945 0.33 ENSDART00000016891
hydroxysteroid (17-beta) dehydrogenase 10
chr16_-_6909034 0.33 ENSDART00000149206
ENSDART00000149778
myelin basic protein b
chr3_+_42217445 0.33 ENSDART00000168228
transmembrane protein 184a
chr21_+_13031206 0.32 ENSDART00000081426
outer dense fiber of sperm tails 2a
chr16_-_51087813 0.32 ENSDART00000165408
si:dkeyp-97a10.3
chr15_-_38027496 0.32 ENSDART00000157550
si:dkey-238d18.15
chr10_+_17470024 0.32

chr24_-_18341006 0.30 ENSDART00000172533
si:dkey-73n8.3
chr1_-_11707288 0.30 ENSDART00000134708
sodium channel and clathrin linker 1
chr2_+_14805305 0.30

chr3_+_25888520 0.29 ENSDART00000135389
FAD-dependent oxidoreductase domain containing 2
chr21_+_43715322 0.29 ENSDART00000115799
Small nucleolar RNA SNORD83
chr7_+_53143741 0.28 ENSDART00000164643
ENSDARG00000104530
chr7_+_21592861 0.28 ENSDART00000159626
si:dkey-85k7.7
chr24_+_17044956 0.27

chr6_+_52242112 0.27 ENSDART00000041549
zinc finger CCCH-type containing 10
chr3_+_30117895 0.27 ENSDART00000122203
Metazoan signal recognition particle RNA
chr16_+_12922721 0.27 ENSDART00000008535
U2 small nuclear RNA auxiliary factor 2a
chr19_-_28699617 0.27 ENSDART00000151756
NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr5_+_3375612 0.27

chr1_+_39965440 0.27 ENSDART00000127907
wu:fc34e06
chr2_-_6380457 0.26 ENSDART00000092182
protein phosphatase, Mg2+/Mn2+ dependent, 1La
chr2_+_58654570 0.26 ENSDART00000164102
ENSDART00000158777
cold inducible RNA binding protein a
chr22_+_5657904 0.25 ENSDART00000138102
deoxyribonuclease 1 like 4, tandem duplicate 2
chr7_-_25991743 0.25 ENSDART00000137769
adaptor-related protein complex 1, sigma 1 subunit
chr6_-_12787356 0.25 ENSDART00000157139
transmembrane BAX inhibitor motif containing 1a
chr8_-_38308535 0.25

chr19_-_40599163 0.24 ENSDART00000150972
EF-hand calcium binding domain 1
chr9_+_32496059 0.24 ENSDART00000078513
MOB family member 4, phocein
chr15_-_8343858 0.24 ENSDART00000137552
si:ch211-113p18.3
chr19_+_7839888 0.24

chr1_+_35058654 0.23 ENSDART00000131284
hedgehog interacting protein
chr18_-_40518772 0.23 ENSDART00000021372
cholinergic receptor, nicotinic, alpha 5
chr23_-_31474216 0.22 ENSDART00000132736
Leber congenital amaurosis 5
chr20_+_32599031 0.22 ENSDART00000145481
SEC63 homolog, protein translocation regulator
chr15_+_20428823 0.22 ENSDART00000062676
SPT5 homolog, DSIF elongation factor subunit
chr18_-_12302111 0.22 ENSDART00000062216
nucleoporin 205
chr1_+_6862901 0.22 ENSDART00000015732
myosin, light polypeptide 3, skeletal muscle
chr10_-_10058065 0.22 ENSDART00000129151
ENSDART00000137392
spermatid perinuclear RNA binding protein
chr23_+_22649652 0.22 ENSDART00000146709
ENSDARG00000095377
chr17_-_5426195 0.21 ENSDART00000035944
chloride intracellular channel 5a
chr6_+_27072030 0.21 ENSDART00000149429
BCL2-related ovarian killer a
chr17_+_1058137 0.21

chr21_+_11274670 0.21 ENSDART00000091835
general transcription factor IIIC, polypeptide 5
chr7_+_5846555 0.20 ENSDART00000083397
histone 1, H4, like
chr3_-_5734028 0.20 ENSDART00000019957
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Ab
chr13_+_36459625 0.20 ENSDART00000030211
glia maturation factor, beta
chr10_+_17414243 0.19 ENSDART00000122663
signal peptide peptidase 3
chr18_-_5822255 0.19 ENSDART00000121503
complexin 3b
chr11_-_29316162 0.19 ENSDART00000163958
Rho guanine nucleotide exchange factor (GEF) 10-like a
chr16_-_25748643 0.19 ENSDART00000132136
derlin 1
chr5_+_23555868 0.19 ENSDART00000124379
GABA(A) receptor-associated protein a
chr8_+_10302071 0.18 ENSDART00000132253
TBC1 domain family, member 22B
chr13_+_36459706 0.18 ENSDART00000138940
glia maturation factor, beta
chr9_+_308260 0.18 ENSDART00000163474
SH3 and cysteine rich domain 3
chr11_+_15988149 0.18 ENSDART00000168083
Metazoan signal recognition particle RNA
chr2_+_49787853 0.18 ENSDART00000056254
signal transducing adaptor family member 2a
chr11_-_35788900 0.18 ENSDART00000025033
glutathione peroxidase 1a
chr3_-_33812379 0.18

chr14_+_28180174 0.17 ENSDART00000161852
stromal antigen 2b
chr1_+_55077656 0.17 ENSDART00000144983
trans-2,3-enoyl-CoA reductase b
chr24_+_12845250 0.17 ENSDART00000126842
hypothetical protein FLJ11011-like (H. sapiens)
chr13_+_36459562 0.16 ENSDART00000030211
glia maturation factor, beta
chr8_-_46963909 0.16

chr19_+_35155538 0.16 ENSDART00000146777
ENSDART00000103276
family with sequence similarity 206, member A
chr9_+_26218474 0.16 ENSDART00000177394
ENSDARG00000107108
chr7_+_45748322 0.16 ENSDART00000169822
cyclin E1
chr2_-_1753058 0.16 ENSDART00000126566
solute carrier family 22, member 23
chr19_+_46631965 0.16 ENSDART00000158703
vacuolar protein sorting 28 (yeast)
chr5_+_64159481 0.16 ENSDART00000073953
leucine rich repeat containing 8 family, member Ab
chr8_-_556380 0.16 ENSDART00000050352
si:ch211-87m7.2
chr19_-_5429428 0.15 ENSDART00000066620
ENSDART00000151398
keratin type 1 c19e
chr8_-_22517872 0.15 ENSDART00000132680
cold shock domain containing E1, RNA-binding
chr12_-_17013870 0.15

chr20_+_32598608 0.15 ENSDART00000021035
ENSDART00000152944
SEC63 homolog, protein translocation regulator
chr9_-_32942783 0.15 ENSDART00000060006
oligodendrocyte lineage transcription factor 2
chr19_-_22761674 0.15

chr23_+_43362722 0.15 ENSDART00000102712
transglutaminase 2, C polypeptide A
chr20_-_35343057 0.15 ENSDART00000113294
frizzled class receptor 3a
chr11_+_5929498 0.15 ENSDART00000104364
ribosomal protein S15
chr5_-_70991958 0.14 ENSDART00000011955
ENSDART00000160380
G protein signaling modulator 1b
chr6_+_42340776 0.14 ENSDART00000015277
glutathione peroxidase 1b
chr20_-_50249356 0.14 ENSDART00000123634
NADH:ubiquinone oxidoreductase subunit B1
chr11_+_12459272 0.14 ENSDART00000172127
Metazoan signal recognition particle RNA
chr19_-_20508993 0.14 ENSDART00000129917
membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)
chr18_-_17527321 0.14

chr23_+_17912784 0.14 ENSDART00000104647
primase, DNA, polypeptide 1
chr14_-_33596430 0.14 ENSDART00000112438
si:ch73-335m24.5
chr3_-_10343029 0.13 ENSDART00000124419
ENSDARG00000101154
chr14_-_15393962 0.13 ENSDART00000161123
ENSDART00000167146
neuralized E3 ubiquitin protein ligase 1B
chr6_-_6091628 0.13 ENSDART00000132350
reticulon 4a
chr3_-_24977167 0.13 ENSDART00000055432
ring-box 1, E3 ubiquitin protein ligase
chr12_-_30385893 0.12 ENSDART00000153108
NHL repeat containing 2
chr5_-_22090338 0.12

chr13_+_49154065 0.12

chr6_+_42340724 0.12 ENSDART00000015277
glutathione peroxidase 1b
chr20_-_27193158 0.12 ENSDART00000062096
si:dkeyp-55f12.3
chr23_+_44543892 0.12 ENSDART00000097644
eph receptor B4b
chr2_+_37312637 0.11 ENSDART00000056519
G protein-coupled receptor 160
chr7_+_20008083 0.11 ENSDART00000012450
dishevelled segment polarity protein 2
chr16_+_38251653 0.11 ENSDART00000044971
myosin IE, b
chr3_+_28808901 0.11 ENSDART00000141904
ENSDART00000077221
lectin, galactoside-binding, soluble, 1 (galectin 1)-like 1
chr3_-_33811737 0.11 ENSDART00000026090
ENSDART00000047660
ENSDART00000111878
general transcription factor IIF, polypeptide 1
chr23_-_30114528 0.10 ENSDART00000131209
coiled-coil domain containing 187
chr8_+_16954190 0.10 ENSDART00000018934
phosphodiesterase 4D, cAMP-specific
chr15_+_37644266 0.10 ENSDART00000099456
presenilin enhancer gamma secretase subunit
chr25_+_14302256 0.10 ENSDART00000130548
cytokine induced apoptosis inhibitor 1
chr12_+_30538113 0.10 ENSDART00000179355
thrombospondin 2b
chr16_+_46728897 0.10 ENSDART00000169767
RAB25, member RAS oncogene family b
chr14_+_596346 0.10 ENSDART00000178302
ENSDARG00000106587
chr23_+_10461899 0.09 ENSDART00000046577
eukaryotic translation initiation factor 4Ba
chr13_-_37001997 0.09 ENSDART00000135510
spectrin repeat containing, nuclear envelope 2b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0048785 hatching gland development(GO:0048785)
0.7 2.8 GO:0098900 regulation of action potential(GO:0098900)
0.4 1.3 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.4 1.7 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.4 1.1 GO:1904035 epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035)
0.4 2.9 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.2 1.0 GO:0043651 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.2 1.2 GO:0031571 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) mitotic G1 DNA damage checkpoint(GO:0031571) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.2 1.9 GO:0033700 phospholipid efflux(GO:0033700)
0.2 0.9 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.2 2.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 0.5 GO:0071846 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) actin filament debranching(GO:0071846)
0.2 1.6 GO:0008406 gonad development(GO:0008406) negative regulation of endodermal cell fate specification(GO:0042664) reproductive structure development(GO:0048608) reproductive system development(GO:0061458)
0.2 0.5 GO:1902024 serine transport(GO:0032329) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 1.5 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1 0.4 GO:0010269 response to selenium ion(GO:0010269)
0.1 0.8 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 2.8 GO:0031167 rRNA methylation(GO:0031167)
0.1 1.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.5 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 1.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.2 GO:0060760 positive regulation of cytokine-mediated signaling pathway(GO:0001961) interferon-gamma-mediated signaling pathway(GO:0060333) positive regulation of response to cytokine stimulus(GO:0060760)
0.1 0.5 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.1 0.5 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.1 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.1 0.2 GO:0021742 abducens nucleus development(GO:0021742)
0.0 0.7 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:0014808 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) sarcoplasmic reticulum calcium ion transport(GO:0070296) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
0.0 0.2 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 0.5 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 1.1 GO:0060030 dorsal convergence(GO:0060030)
0.0 0.2 GO:0035094 response to nicotine(GO:0035094)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.3 GO:0098508 endothelial to hematopoietic transition(GO:0098508)
0.0 0.4 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.3 GO:0046660 female sex differentiation(GO:0046660)
0.0 0.2 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.9 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.6 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.3 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.1 GO:0042987 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.0 0.8 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.1 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.1 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.1 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.0 0.4 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.3 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.0 0.4 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.3 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.2 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.9 GO:0061700 GATOR2 complex(GO:0061700)
0.3 2.8 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.1 0.7 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.5 GO:0072487 MSL complex(GO:0072487)
0.1 2.1 GO:0043204 perikaryon(GO:0043204)
0.1 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.2 GO:1990077 primosome complex(GO:1990077)
0.0 1.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 1.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 1.5 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0031207 endoplasmic reticulum Sec complex(GO:0031205) Sec62/Sec63 complex(GO:0031207)
0.0 0.3 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.3 GO:0043209 myelin sheath(GO:0043209)
0.0 1.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.9 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.8 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0043195 terminal bouton(GO:0043195)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.4 2.9 GO:0070728 leucine binding(GO:0070728)
0.3 1.6 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.3 1.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.3 1.7 GO:1901612 cardiolipin binding(GO:1901612)
0.3 1.6 GO:0001223 transcription coactivator binding(GO:0001223)
0.3 2.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.2 1.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.2 0.7 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.2 2.8 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.8 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.5 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 1.0 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.3 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.9 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.0 0.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 3.1 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.6 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.3 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 2.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.0 0.1 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 3.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.0 0.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 1.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.1 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.3 REACTOME MYOGENESIS Genes involved in Myogenesis