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Results for plagx

Z-value: 0.72

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Transcription factors associated with plagx

Gene Symbol Gene ID Gene Info
ENSDARG00000036855 pleiomorphic adenoma gene X

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
plagxdr10_dc_chr23_+_32085181_320853040.774.8e-04Click!

Activity profile of plagx motif

Sorted Z-values of plagx motif

Network of associatons between targets according to the STRING database.

First level regulatory network of plagx

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr9_-_22499899 3.12 ENSDART00000147358
crystallin, gamma M2d10
chr7_-_69639922 2.18

chr20_-_44598129 2.15 ENSDART00000012229
FK506 binding protein 1b
chr15_+_43776204 2.05 ENSDART00000122238
tyrosinase
chr24_+_35676505 1.81 ENSDART00000122734
CCAAT/enhancer binding protein (C/EBP), delta
chr23_+_45020761 1.58 ENSDART00000159104
ATPase, Na+/K+ transporting, beta 2a polypeptide
chr16_-_35633520 1.35 ENSDART00000169868
ENSDART00000166606
sex comb on midleg homolog 1 (Drosophila)
chr12_-_25825072 1.31

chr7_+_44269171 1.26 ENSDART00000149981
CKLF-like MARVEL transmembrane domain containing 3
chr4_+_22020246 1.18 ENSDART00000112035
ENSDART00000127664
myogenic factor 5
chr12_-_30230492 1.09 ENSDART00000152985
von Willebrand factor A domain containing 2
chr19_-_4079427 1.06 ENSDART00000170325
MAP7 domain containing 1b
chr5_+_63103958 1.01

chr22_-_15930756 0.98 ENSDART00000080047
epidermal growth factor receptor pathway substrate 15-like 1a
chr1_+_48923897 0.97 ENSDART00000101004
ENSDART00000164000
ENSDART00000142957
collagen, type XVII, alpha 1a
chr19_+_9113356 0.97 ENSDART00000127755
ash1 (absent, small, or homeotic)-like (Drosophila)
chr12_+_40919018 0.96 ENSDART00000176047
ENSDARG00000108020
chr4_+_19545842 0.93 ENSDART00000140028
leucine rich repeat containing 4.1
chr25_+_28329427 0.73 ENSDART00000160619
solute carrier family 41 (magnesium transporter), member 2a
chr19_+_38033219 0.71 ENSDART00000158960
thrombospondin, type I, domain containing 7Aa
chr19_-_20508993 0.67 ENSDART00000129917
membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)
chr19_+_21783111 0.64 ENSDART00000024639
teashirt zinc finger homeobox 1
chr1_+_46754799 0.62 ENSDART00000126904
ENSDART00000007262
gap junction protein alpha 8 paralog b
chr1_+_52373036 0.54 ENSDART00000129747
inositol polyphosphate-4-phosphatase type II B
chr10_+_41237437 0.52 ENSDART00000141657
annexin A4
chr7_+_73594790 0.43 ENSDART00000123081
zgc:173552
chr12_+_16391933 0.33 ENSDART00000113810
ankyrin repeat domain 1b (cardiac muscle)
chr13_-_22653869 0.32

chr3_-_25290558 0.32 ENSDART00000154200
bromodomain PHD finger transcription factor
chr3_+_18645970 0.27 ENSDART00000042368
fumarylacetoacetate hydrolase domain containing 1
chr24_-_35646129 0.27 ENSDART00000026578
ubiquitin-conjugating enzyme E2 variant 2
chr2_-_24330667 0.27

chr6_-_35417797 0.24 ENSDART00000016586
regulator of G protein signaling 5a
chr3_+_35377667 0.21

chr21_-_20983913 0.20 ENSDART00000132091
eukaryotic translation initiation factor 4E binding protein 1
chr16_-_36844763 0.19 ENSDART00000145697
calbindin 1
chr16_+_35633745 0.10

chr2_-_24330786 0.07

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0042423 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.3 1.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 1.6 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 2.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.2 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.0 3.1 GO:0007601 visual perception(GO:0007601)
0.0 0.3 GO:0042766 nucleosome mobilization(GO:0042766)
0.0 1.1 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.7 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.3 GO:0006301 postreplication repair(GO:0006301)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 1.0 GO:0016586 RSC complex(GO:0016586)
0.2 1.6 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.1 0.6 GO:0005921 gap junction(GO:0005921)
0.1 1.0 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 1.0 GO:0005604 basement membrane(GO:0005604)
0.0 0.2 GO:0043195 terminal bouton(GO:0043195)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
0.2 0.6 GO:0005243 gap junction channel activity(GO:0005243)
0.1 3.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.6 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.5 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 2.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 1.0 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation