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Results for pou1f1

Z-value: 1.38

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Transcription factors associated with pou1f1

Gene Symbol Gene ID Gene Info
ENSDARG00000058924 POU class 1 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou1f1dr10_dc_chr9_-_19154264_191542700.862.2e-05Click!

Activity profile of pou1f1 motif

Sorted Z-values of pou1f1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of pou1f1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_-_17590507 10.55 ENSDART00000010144
parvalbumin 2
chr4_+_9668755 6.88 ENSDART00000004604
si:dkey-153k10.9
chr13_+_24148599 6.67 ENSDART00000058629
actin, alpha 1b, skeletal muscle
chr3_-_32686790 4.97 ENSDART00000075465
myosin light chain, phosphorylatable, fast skeletal muscle a
chr21_+_25199691 4.93 ENSDART00000168140
ENSDART00000112783
transmembrane protein 45B
chr3_+_28808901 4.61 ENSDART00000141904
ENSDART00000077221
lectin, galactoside-binding, soluble, 1 (galectin 1)-like 1
chr7_+_58718614 4.00 ENSDART00000157873
3-hydroxyacyl-CoA dehydratase 1
chr9_-_22402341 3.93 ENSDART00000110656
crystallin, gamma M2d20
chr20_+_19613133 3.68 ENSDART00000152548
ENSDART00000063696
all-trans retinoic acid-induced differentiation factor
chr23_+_19887319 3.57 ENSDART00000139192
emerin (Emery-Dreifuss muscular dystrophy)
chr23_-_42775849 3.48 ENSDART00000149944
glutathione peroxidase 7
chr23_-_6588073 3.15 ENSDART00000092214
ENSDART00000138020
bone morphogenetic protein 7b
chr14_+_47326080 3.12 ENSDART00000047525
crystallin, beta A1, like 1
chr15_+_9351511 3.07 ENSDART00000144381
sarcoglycan, gamma
chr10_+_18994733 3.03 ENSDART00000146517
dihydropyrimidinase-like 2b
chr20_-_9107294 2.99 ENSDART00000140792
OMA1 zinc metallopeptidase
chr22_-_22846670 2.91 ENSDART00000176355
ENSDARG00000108442
chr24_-_1155215 2.89 ENSDART00000177356
integrin, beta 1a
chr7_-_73866202 2.81

chr16_+_46145286 2.74 ENSDART00000172232
synaptic vesicle glycoprotein 2A
chr24_+_32261533 2.69 ENSDART00000003745
vimentin
chr19_+_43763483 2.68 ENSDART00000136695
Yes-related kinase
chr11_+_30416115 2.66 ENSDART00000161662
tau tubulin kinase 1a
chr15_+_43714699 2.53 ENSDART00000168191
ENSDARG00000102235
chr19_+_44185325 2.50 ENSDART00000063870
ribosomal protein L11
chr21_-_43020159 2.47 ENSDART00000065097
dihydropyrimidinase-like 3
chr6_-_16590883 2.46 ENSDART00000153552
nodal modulator
chr3_-_15849644 2.45 ENSDART00000160668
NME/NM23 nucleoside diphosphate kinase 3
chr5_+_40722565 2.31 ENSDART00000097546
AT rich interactive domain 3C (BRIGHT-like)
chr16_+_43249142 2.28 ENSDART00000154493
ADAM metallopeptidase domain 22
chr10_+_9575 2.26

chr19_-_39048324 2.24 ENSDART00000086717
collagen, type XVI, alpha 1
chr4_+_4841191 2.23 ENSDART00000130818
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr9_+_36092350 2.22 ENSDART00000005086
ATPase, Na+/K+ transporting, alpha 1b polypeptide
chr5_-_40894631 2.19 ENSDART00000121840
eukaryotic translation elongation factor 2, like 2
chr9_-_1949904 2.14 ENSDART00000082355
homeobox D4a
chr16_-_28921444 2.12 ENSDART00000078543
synaptotagmin XIb
chr4_-_73485204 2.12 ENSDART00000122898
PHD finger protein 21B
chr23_-_21520413 2.11 ENSDART00000044080
ENSDART00000112929
hairy-related 12
chr16_+_46435014 2.08 ENSDART00000144000
rapunzel 2
chr2_+_20748431 2.08 ENSDART00000137848
palmdelphin a
chr19_-_35739239 2.04

chr14_-_24094142 2.00 ENSDART00000126894
family with sequence similarity 13, member B
chr17_-_30685367 1.99 ENSDART00000114358
zgc:194392
chr14_-_4038642 1.97 ENSDART00000077348
caspase 3, apoptosis-related cysteine peptidase b
chr19_+_12995955 1.97 ENSDART00000132892
collagen triple helix repeat containing 1a
chr1_-_53403731 1.93 ENSDART00000171722
single-pass membrane protein with aspartate-rich tail 1b
chr7_+_19243998 1.89 ENSDART00000173766
si:ch211-212k18.8
chr14_-_45883839 1.86

chr21_+_45802046 1.85 ENSDART00000038657
fatty acid hydroxylase domain containing 2
chr7_+_25758469 1.80 ENSDART00000101126
arachidonate 12-lipoxygenase
chr1_+_4704661 1.78 ENSDART00000040204
tubulin, alpha 8 like 2
chr5_+_62987426 1.78 ENSDART00000178937
dynamin 1b
chr19_-_27284726 1.76 ENSDART00000089699
proline-rich transmembrane protein 1
chr4_+_1750689 1.76 ENSDART00000146779
solute carrier family 38, member 2
chr2_+_16492315 1.75 ENSDART00000135783
selenoprotein J
chr12_+_2988101 1.73 ENSDART00000044690
ENSDART00000122905
ras-related C3 botulinum toxin substrate 3b (rho family, small GTP binding protein Rac3)
chr5_-_44229464 1.73 ENSDART00000019104
fructose-1,6-bisphosphatase 2
chr16_-_28943421 1.71 ENSDART00000149501
si:dkey-239n17.4
chr13_-_49983998 1.70

chr11_-_1374026 1.68 ENSDART00000172953
ribosomal protein L29
chr5_+_71028018 1.67 ENSDART00000164893
ENSDART00000159658
ENSDART00000097164
ENSDART00000124939
ENSDART00000171230
LIM homeobox 3
chr1_-_22160662 1.66 ENSDART00000054386
quinoid dihydropteridine reductase b1
chr4_+_22759177 1.65 ENSDART00000146272
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr2_+_29729161 1.65 ENSDART00000141666
ENSDARG00000093205
chr13_-_9554501 1.64 ENSDART00000139541
ENSDARG00000069828
chr13_+_9100463 1.63 ENSDART00000058064
ENSDARG00000039726
chr15_-_18226612 1.62 ENSDART00000012064
PIH1 domain containing 2
chr24_+_9335428 1.60 ENSDART00000132688
si:ch211-285f17.1
chr14_+_2969679 1.57 ENSDART00000044678
ENSDARG00000034011
chr20_+_7596461 1.56 ENSDART00000127975
ENSDART00000132481
ENSDART00000144551
biogenesis of lysosomal organelles complex-1, subunit 2
chr4_-_2615160 1.55 ENSDART00000140760
E2F transcription factor 7
chr14_-_16791447 1.55 ENSDART00000158002
ENSDARG00000103278
chr5_-_9162684 1.54

chr10_-_43924675 1.54 ENSDART00000052307
arrestin domain containing 3b
chr13_+_7109810 1.53 ENSDART00000080975
tumor necrosis factor, alpha-induced protein 2b
chr18_+_24932972 1.53 ENSDART00000008638
repulsive guidance molecule family member a
chr21_+_28441951 1.53 ENSDART00000077887
solute carrier family 22 (organic anion transporter), member 6, like
chr3_+_50511676 1.52 ENSDART00000102202
phosphatidic acid phosphatase type 2D
chr12_+_27040886 1.51

chr5_-_2014043 1.48 ENSDART00000064012
carbonic anhydrase IV a
chr2_-_44402486 1.46 ENSDART00000011188
ENSDART00000093298
ATPase, Na+/K+ transporting, alpha 2a polypeptide
chr9_+_34832049 1.46 ENSDART00000100735
ENSDART00000133996
short stature homeobox
chr15_-_21003820 1.44 ENSDART00000152371
ubiquitin specific peptidase 2a
chr4_-_935448 1.42 ENSDART00000171855
single-minded family bHLH transcription factor 1b
chr12_+_13244482 1.42 ENSDART00000137757
interferon regulatory factor 9
chr12_+_13870214 1.41 ENSDART00000066367
FK506 binding protein 10b
chr21_+_44203036 1.41

chr6_-_50705420 1.41 ENSDART00000074100
oxidative stress induced growth inhibitor 1
chr10_+_13042496 1.40 ENSDART00000158919
lysophosphatidic acid receptor 1
chr20_-_3970778 1.40 ENSDART00000178724
ENSDART00000178565
tripartite motif containing 67
chr3_-_19050721 1.39 ENSDART00000131503
regulatory factor X, 1a (influences HLA class II expression)
chr24_+_24686591 1.39 ENSDART00000080969
tripartite motif containing 55b
chr8_+_50994889 1.39 ENSDART00000142061
si:dkey-32e23.4
chr11_-_26595578 1.38 ENSDART00000153519
IQ motif and Sec7 domain 1b
chr10_-_35293024 1.38 ENSDART00000145804
yippee-like 2a
chr6_+_52350428 1.36 ENSDART00000151612
si:ch211-239j9.1
chr18_+_21419735 1.36 ENSDART00000144523
N-terminal EF-hand calcium binding protein 2
chr20_+_3095763 1.35 ENSDART00000133435
centrosomal protein 170B
chr21_-_30508374 1.34 ENSDART00000019199
RAB39B, member RAS oncogene family a
chr19_+_20181908 1.33 ENSDART00000158987
homeobox A4a
chr19_+_5562107 1.33 ENSDART00000082080
junction plakoglobin b
chr7_-_73866265 1.33

chr4_+_5246465 1.33 ENSDART00000137966
coiled-coil domain containing 167
chr8_-_17031599 1.33 ENSDART00000132687
RAB3C, member RAS oncogene family
chr13_-_31491759 1.32 ENSDART00000057432
SIX homeobox 1a
chr14_-_33483075 1.32 ENSDART00000158870
si:dkey-76i15.1
chr11_+_15935769 1.30 ENSDART00000158824
chitobiase, di-N-acetyl-
chr1_+_39844690 1.29 ENSDART00000122059
short coiled-coil protein a
chr24_+_37692365 1.29

chr14_-_47129958 1.29 ENSDART00000172166
NADH:ubiquinone oxidoreductase subunit C1
chr10_+_26786051 1.26 ENSDART00000100329
coagulation factor IXb
chr17_+_25500291 1.24 ENSDART00000041721
crystallin beta-gamma domain containing 1a
chr24_-_24306469 1.21 ENSDART00000154149
ENSDARG00000097984
chr8_+_2428689 1.20 ENSDART00000081325
dynein, light chain, LC8-type 1
chr21_+_6858073 1.18 ENSDART00000139493
olfactomedin 1b
chr7_+_21006803 1.16 ENSDART00000052942
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr15_+_9351211 1.14 ENSDART00000144381
sarcoglycan, gamma
chr8_+_24725855 1.14 ENSDART00000078656
solute carrier family 16, member 4
chr17_-_36948926 1.13 ENSDART00000045287
microtubule-associated protein, RP/EB family, member 3a
chr6_+_6640324 1.13 ENSDART00000150967
si:ch211-85n16.3
chr8_+_43334181 1.12 ENSDART00000038566
family with sequence similarity 101, member A
chr1_+_40795366 1.11 ENSDART00000146310
deltex 4, E3 ubiquitin ligase
chr16_-_2570425 1.10

chr2_-_17721575 1.10 ENSDART00000141188
ENSDART00000100201
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr16_+_9141325 1.06

chr2_+_29507819 1.05

chr10_-_35714800 1.05

chr14_-_47083485 1.05 ENSDART00000172512
E74-like factor 2a (ets domain transcription factor)
chr25_-_21718782 1.04 ENSDART00000175132
ENSDARG00000051873
chr5_-_40894693 1.03 ENSDART00000051081
eukaryotic translation elongation factor 2, like 2
chr2_+_21267793 1.03 ENSDART00000099913
phospholipase A2, group IVAa (cytosolic, calcium-dependent)
chr14_-_31514534 1.03 ENSDART00000003345
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr8_+_28240085 1.01 ENSDART00000110857
family with sequence similarity 212, member B
chr10_-_11303185 1.01 ENSDART00000146727
polypyrimidine tract binding protein 3
chr8_-_17951834 1.00 ENSDART00000112699
fucose-1-phosphate guanylyltransferase
chr2_+_44718147 0.99 ENSDART00000098132
kelch-like family member 24a
chr2_-_44402452 0.98 ENSDART00000011188
ENSDART00000093298
ATPase, Na+/K+ transporting, alpha 2a polypeptide
chr5_+_65754237 0.98 ENSDART00000170757
kinetochore associated 1
chr7_+_66660781 0.97 ENSDART00000082664
SET binding factor 2
chr14_-_30630835 0.97 ENSDART00000010512
zgc:92907
chr3_-_12087518 0.97 ENSDART00000081374
cilia and flagella associated protein 70
chr8_-_12253026 0.97 ENSDART00000091612
DAB2 interacting protein a
chr16_+_43249077 0.97 ENSDART00000154493
ADAM metallopeptidase domain 22
chr16_+_53602834 0.96 ENSDART00000074653
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1b (glutamate binding)
chr24_+_192889 0.96 ENSDART00000067764
serine/threonine kinase 17a
chr20_+_36098607 0.96 ENSDART00000021456
opsin 5
chr13_+_33138144 0.95 ENSDART00000002095
transmembrane protein 39B
chr1_-_30801520 0.94 ENSDART00000007770
ladybird homeobox 1b
chr16_+_37519702 0.94

chr1_-_661529 0.93 ENSDART00000166786
ENSDART00000170483
amyloid beta (A4) precursor protein a
chr2_+_4144790 0.92 ENSDART00000160806
mohawk homeobox b
chr15_-_21078596 0.91 ENSDART00000154019
ENSDARG00000093199
chr12_-_41128584 0.90

chr21_+_27241416 0.90

chr12_-_28248133 0.90 ENSDART00000016283
proteasome 26S subunit, non-ATPase 11b
chr4_-_885413 0.90 ENSDART00000022668
crystallin beta-gamma domain containing 1b
chr15_+_32439470 0.90 ENSDART00000153657
tripartite motif containing 3a
chr20_+_25326042 0.89 ENSDART00000130494
monooxygenase, DBH-like 1
chr16_+_29060022 0.88 ENSDART00000088023
gon-4-like (C. elegans)
chr9_-_43736549 0.87 ENSDART00000140526
zinc finger protein 385B
chr23_-_23474703 0.85 ENSDART00000078936
hairy-related 9
chr9_+_7745593 0.85 ENSDART00000061716
motor neuron and pancreas homeobox 2a
chr6_-_51666164 0.85

chr12_-_425381 0.84 ENSDART00000083827
heparan sulfate (glucosamine) 3-O-sulfotransferase 3-like
chr5_-_55263153 0.84 ENSDART00000050966
solute carrier family 25, member 46
chr17_+_2551397 0.84 ENSDART00000178759
potassium channel, subfamily K, member 10b
chr9_+_24255064 0.83 ENSDART00000101577
ENSDART00000159324
ENSDART00000023196
ENSDART00000079689
ENSDART00000172743
ENSDART00000171577
leucine rich repeat (in FLII) interacting protein 1a
chr8_-_2375664 0.83 ENSDART00000144017
voltage-dependent anion channel 3
chr13_-_29290894 0.83 ENSDART00000150228
choline O-acetyltransferase a
chr19_-_39048402 0.83 ENSDART00000086717
collagen, type XVI, alpha 1
chr14_-_28228583 0.83 ENSDART00000054088
zgc:113364
chr3_-_19218660 0.82 ENSDART00000132987
sphingosine-1-phosphate receptor 5a
chr12_-_552235 0.81 ENSDART00000168586
ENSDART00000158355
brain specific kinase 146
chr18_-_48375325 0.80

chr16_+_21065200 0.77 ENSDART00000006429
3-hydroxyisobutyrate dehydrogenase b
chr18_-_43890514 0.77 ENSDART00000087382
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr8_-_20357907 0.76

chr6_+_9192009 0.76 ENSDART00000022620
kalirin RhoGEF kinase b
chr25_-_25339268 0.75 ENSDART00000171589
v-Ha-ras Harvey rat sarcoma viral oncogene homolog a
chr6_+_14854101 0.75 ENSDART00000087782
mitochondrial ribosomal protein S9
chr17_+_10345498 0.73 ENSDART00000081659
ENSDART00000169120
ENSDART00000170970
ENSDART00000140391
TYRO3 protein tyrosine kinase
chr7_-_29003965 0.73

chr16_-_21334269 0.73 ENSDART00000145837
si:dkey-271j15.3
chr9_-_53380782 0.72 ENSDART00000166906
transient receptor potential cation channel, subfamily M, member 2
chr17_+_44583892 0.72 ENSDART00000156625
placental growth factor b
chr5_-_42304154 0.71 ENSDART00000112807
chemokine (C-X-C motif) ligand 20
chr1_+_51087450 0.71 ENSDART00000040397
peroxiredoxin 2
chr6_+_7376428 0.71 ENSDART00000057823
proliferation-associated 2G4, a
chr19_-_5851328 0.70 ENSDART00000133106
si:ch211-264f5.6
chr9_+_11311198 0.70 ENSDART00000110691
wingless-type MMTV integration site family, member 6b
chr14_-_1342450 0.69 ENSDART00000060417
centrin 4
chr3_-_7220340 0.69

chr3_-_38642067 0.69 ENSDART00000155518
zinc finger protein 281a
chr18_-_13234871 0.68 ENSDART00000142942
kelch-like family member 36
chr7_-_71290605 0.67 ENSDART00000111797
alkaline ceramidase 2
chr8_-_20357968 0.67

chr16_-_53008678 0.65

chr12_-_22438379 0.65 ENSDART00000177715
ENSDARG00000108493
chr14_-_23784679 0.65 ENSDART00000158576
muscle segment homeobox 2a

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.7 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.8 2.5 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.8 2.4 GO:0010084 specification of organ axis polarity(GO:0010084)
0.5 1.6 GO:0032875 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.5 1.5 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.5 5.5 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.5 1.4 GO:1903146 regulation of mitophagy(GO:1903146)
0.5 1.8 GO:0043651 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.4 1.3 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.4 1.8 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.4 2.5 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.3 0.9 GO:0009713 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.3 0.8 GO:0051701 interaction with host(GO:0051701)
0.3 1.4 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.3 1.9 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.3 1.6 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.3 1.0 GO:0001541 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698) inflammatory response to wounding(GO:0090594)
0.3 0.8 GO:0006574 valine catabolic process(GO:0006574)
0.3 1.5 GO:0051601 exocyst localization(GO:0051601)
0.3 1.8 GO:0006868 glutamine transport(GO:0006868)
0.2 1.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.2 2.7 GO:0048246 macrophage chemotaxis(GO:0048246)
0.2 1.2 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 1.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.2 2.0 GO:0030216 keratinocyte differentiation(GO:0030216)
0.2 1.6 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.2 1.4 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.2 1.3 GO:0014857 skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857)
0.2 0.7 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.2 2.9 GO:1903672 positive regulation of sprouting angiogenesis(GO:1903672)
0.2 0.8 GO:0008291 neuromuscular synaptic transmission(GO:0007274) acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.2 1.0 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.2 0.6 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 2.2 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 2.5 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 1.1 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 0.4 GO:0032475 otolith formation(GO:0032475)
0.1 4.0 GO:0030497 fatty acid elongation(GO:0030497)
0.1 0.4 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.1 2.1 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 0.2 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.1 0.7 GO:0060753 mast cell chemotaxis(GO:0002551) positive regulation of leukocyte chemotaxis(GO:0002690) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 0.7 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.1 0.3 GO:0030279 negative regulation of ossification(GO:0030279)
0.1 6.7 GO:0048741 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.1 0.6 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 0.8 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.6 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.1 3.1 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 0.6 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.7 GO:0000305 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 1.0 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.1 2.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.8 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.2 GO:0045117 azole transport(GO:0045117)
0.1 0.5 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.1 7.0 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 1.7 GO:0021654 rhombomere boundary formation(GO:0021654)
0.1 0.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 1.8 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 1.0 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 2.0 GO:0030282 bone mineralization(GO:0030282)
0.1 0.5 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.1 1.0 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.3 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 0.3 GO:0006801 superoxide metabolic process(GO:0006801)
0.1 1.2 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.9 GO:0043248 proteasome assembly(GO:0043248)
0.1 1.4 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 3.2 GO:0006414 translational elongation(GO:0006414)
0.1 0.4 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.1 0.6 GO:0031623 receptor internalization(GO:0031623)
0.1 0.2 GO:0006788 heme oxidation(GO:0006788)
0.0 2.1 GO:0001570 vasculogenesis(GO:0001570)
0.0 0.5 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 3.3 GO:0006979 response to oxidative stress(GO:0006979)
0.0 0.8 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.3 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.0 0.9 GO:0050768 negative regulation of neurogenesis(GO:0050768)
0.0 0.5 GO:0006265 DNA topological change(GO:0006265)
0.0 2.7 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.6 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 4.2 GO:0048738 cardiac muscle tissue development(GO:0048738)
0.0 0.1 GO:0030817 regulation of cAMP metabolic process(GO:0030814) regulation of cAMP biosynthetic process(GO:0030817) regulation of adenylate cyclase activity(GO:0045761)
0.0 1.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.3 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.7 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 1.5 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.9 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 1.0 GO:1901215 negative regulation of neuron death(GO:1901215)
0.0 0.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0046958 learning(GO:0007612) nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 2.1 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 1.7 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 1.3 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 0.5 GO:0043113 receptor clustering(GO:0043113)
0.0 1.3 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 1.2 GO:0010506 regulation of autophagy(GO:0010506)
0.0 2.8 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.8 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 2.7 GO:0042060 wound healing(GO:0042060)
0.0 0.6 GO:0050821 protein stabilization(GO:0050821)
0.0 2.9 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.1 GO:0098781 ncRNA transcription(GO:0098781)
0.0 1.0 GO:0016579 protein deubiquitination(GO:0016579)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.5 6.5 GO:0005869 dynactin complex(GO:0005869)
0.4 1.8 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.3 1.6 GO:0097255 R2TP complex(GO:0097255)
0.3 1.9 GO:1990246 uniplex complex(GO:1990246)
0.2 1.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.4 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1 2.9 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.5 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 1.7 GO:0000145 exocyst(GO:0000145)
0.1 1.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 3.4 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.9 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.6 GO:0001650 fibrillar center(GO:0001650)
0.1 0.8 GO:0046930 pore complex(GO:0046930)
0.1 4.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.9 GO:0030667 secretory granule membrane(GO:0030667)
0.1 2.5 GO:0030426 growth cone(GO:0030426)
0.1 2.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 0.2 GO:0071914 prominosome(GO:0071914)
0.1 0.2 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 1.1 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.5 GO:1990752 microtubule end(GO:1990752)
0.1 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.6 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 2.5 GO:0005581 collagen trimer(GO:0005581)
0.0 1.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 3.4 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.8 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 2.7 GO:0005882 intermediate filament(GO:0005882)
0.0 4.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.6 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.4 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 3.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 2.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 3.1 GO:0043005 neuron projection(GO:0043005)
0.0 1.0 GO:0030027 lamellipodium(GO:0030027)
0.0 0.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 1.6 GO:0009986 cell surface(GO:0009986)
0.0 0.7 GO:0005814 centriole(GO:0005814)
0.0 6.0 GO:0005615 extracellular space(GO:0005615)
0.0 7.3 GO:0031226 intrinsic component of plasma membrane(GO:0031226)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
1.2 4.6 GO:0016936 galactoside binding(GO:0016936)
1.0 2.9 GO:0019960 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.8 5.5 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.5 4.7 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.4 1.3 GO:0004568 chitinase activity(GO:0004568)
0.3 3.1 GO:0070700 BMP receptor binding(GO:0070700)
0.3 1.0 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.3 1.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.3 0.8 GO:0015288 porin activity(GO:0015288)
0.3 0.8 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.3 2.6 GO:0015026 coreceptor activity(GO:0015026)
0.2 7.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 0.9 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2 3.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 1.8 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.2 3.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.2 0.7 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.2 0.5 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
0.2 0.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 0.6 GO:0019808 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.2 1.0 GO:0016918 retinal binding(GO:0016918)
0.2 1.6 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.2 2.0 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.1 1.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.5 GO:0000215 tRNA 2'-phosphotransferase activity(GO:0000215) 2'-phosphotransferase activity(GO:0008665)
0.1 0.5 GO:0030507 spectrin binding(GO:0030507)
0.1 0.7 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 0.7 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 1.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.2 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1 1.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.3 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.1 2.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 3.2 GO:0043022 ribosome binding(GO:0043022)
0.1 0.7 GO:0008009 chemokine activity(GO:0008009) chemokine receptor binding(GO:0042379)
0.1 1.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.8 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.1 1.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.4 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 0.8 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.5 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.5 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 1.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 3.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 1.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.3 GO:0036122 BMP binding(GO:0036122)
0.1 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:0008905 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.0 0.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 3.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 1.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 18.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.7 GO:0019003 GDP binding(GO:0019003)
0.0 0.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.9 GO:0008201 heparin binding(GO:0008201)
0.0 3.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 2.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 1.4 GO:0008083 growth factor activity(GO:0008083)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.5 GO:0008514 organic anion transmembrane transporter activity(GO:0008514)
0.0 1.2 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.5 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.2 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 3.1 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.5 PID BMP PATHWAY BMP receptor signaling
0.0 2.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.4 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.5 PID E2F PATHWAY E2F transcription factor network
0.0 2.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 ST P38 MAPK PATHWAY p38 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.6 1.8 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.4 2.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.7 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.1 1.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 3.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 0.8 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 4.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 2.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.6 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.6 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G