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Results for pou2f2a

Z-value: 1.90

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Transcription factors associated with pou2f2a

Gene Symbol Gene ID Gene Info
pou2f2a
ENSDARG00000019658 POU class 2 homeobox 2a
pou2f2a
ENSDARG00000036816 POU class 2 homeobox 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou2f2adr10_dc_chr16_+_11027394_110274420.572.2e-02Click!

Activity profile of pou2f2a motif

Sorted Z-values of pou2f2a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of pou2f2a

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_-_6078015 6.91 ENSDART00000165715
BX284638.1
ENSDARG00000098850
chr16_+_17808623 5.01 ENSDART00000149596
si:dkey-87o1.2
si:dkey-87o1.2
chr23_+_21546553 4.73 ENSDART00000142921
si:ch73-21g5.7
si:ch73-21g5.7
chr23_+_23305483 4.53 ENSDART00000126479
plekhn1
pleckstrin homology domain containing, family N member 1
chr6_-_39315024 4.44 ENSDART00000012644
krt4
keratin 4
chr5_-_42272455 4.35 ENSDART00000161586
flot2a
flotillin 2a
chr6_+_56163589 3.87 ENSDART00000150219
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr16_+_737615 3.67 ENSDART00000161774
irx1a
iroquois homeobox 1a
chr15_-_29454583 3.62 ENSDART00000145976
serpinh1b
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr9_-_43178744 3.45

chr15_-_16076874 3.35 ENSDART00000144138
hnf1ba
HNF1 homeobox Ba
chr15_+_7190427 3.34 ENSDART00000109394
her13
hairy-related 13
chr14_-_32624823 3.33 ENSDART00000114973
cdx4
caudal type homeobox 4
chr14_+_35885903 3.19 ENSDART00000052569
pitx2
paired-like homeodomain 2
chr23_-_31446156 3.16 ENSDART00000053367
hmgn3
high mobility group nucleosomal binding domain 3
chr5_+_12786897 3.13

chr20_+_40247918 3.04 ENSDART00000121818
trdn
triadin
chr5_-_65349550 2.99 ENSDART00000164228
nrarpb
notch-regulated ankyrin repeat protein b
chr10_+_17494274 2.97

chr8_-_22945616 2.91

chr3_+_28450576 2.89 ENSDART00000150893
sept12
septin 12
chr9_-_54126121 2.87 ENSDART00000126314
pcdh8
protocadherin 8
chr16_-_24634751 2.84 ENSDART00000108590
si:ch211-79k12.1
si:ch211-79k12.1
chr13_-_5953330 2.84 ENSDART00000099224
dld
deltaD
chr11_-_11591394 2.80 ENSDART00000142208
zgc:110712
zgc:110712
chr20_-_22576513 2.74 ENSDART00000103510
pdgfra
platelet-derived growth factor receptor, alpha polypeptide
chr11_-_29910947 2.59 ENSDART00000156121
scml2
sex comb on midleg-like 2 (Drosophila)
chr8_+_28584427 2.56 ENSDART00000097213
tcf15
transcription factor 15
chr14_-_40454194 2.52 ENSDART00000166621
ef1
E74-like factor 1 (ets domain transcription factor)
chr1_+_53353690 2.52 ENSDART00000126339
dla
deltaA
chr17_+_26946957 2.51 ENSDART00000114215
grhl3
grainyhead-like transcription factor 3
chr1_-_46141359 2.51 ENSDART00000142406
si:ch73-160h15.3
si:ch73-160h15.3
chr19_+_22478256 2.47 ENSDART00000100181
sall3b
spalt-like transcription factor 3b
chr6_-_343209 2.46

chr23_-_4990023 2.45 ENSDART00000142699
taz
tafazzin
chr19_+_3713027 2.45 ENSDART00000125673
nedd9
neural precursor cell expressed, developmentally down-regulated 9
chr1_+_50395721 2.45 ENSDART00000134065
dpy30
dpy-30 histone methyltransferase complex regulatory subunit
chr9_-_53898458 2.41 ENSDART00000175619
ENSDART00000179009
CABZ01078244.2
ENSDARG00000107473
chr25_-_3704591 2.38 ENSDART00000055843
cd151
CD151 molecule
chr14_-_4038642 2.36 ENSDART00000077348
casp3b
caspase 3, apoptosis-related cysteine peptidase b
chr7_-_11812634 2.28 ENSDART00000101537
mex3b
mex-3 RNA binding family member B
chr10_+_36096599 2.27

chr14_-_7774262 2.27 ENSDART00000045109
zgc:92242
zgc:92242
chr9_-_53898524 2.27 ENSDART00000175619
ENSDART00000179009
CABZ01078244.2
ENSDARG00000107473
chr17_+_33766838 2.24 ENSDART00000132294
fut8a
fucosyltransferase 8a (alpha (1,6) fucosyltransferase)
chr25_-_2485276 2.24 ENSDART00000154889
ENSDART00000155027
BX957346.1
ENSDARG00000096850
chr1_-_24747855 2.21 ENSDART00000111686
fhdc1
FH2 domain containing 1
chr10_+_10428297 2.18 ENSDART00000179214
sardh
sarcosine dehydrogenase
chr22_+_36687668 2.15 ENSDART00000134031
b3gnt7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr7_-_55406347 2.13 ENSDART00000021009
cbfa2t3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr21_+_19034242 2.09 ENSDART00000123309
nkx6.1
NK6 homeobox 1
chr2_+_55859099 2.08 ENSDART00000097753
ENSDART00000141688
nmrk2
nicotinamide riboside kinase 2
chr11_+_5745644 2.07 ENSDART00000179139
arid3a
AT rich interactive domain 3A (BRIGHT-like)
chr24_-_8590572 2.06 ENSDART00000082349
tfap2a
transcription factor AP-2 alpha
chr11_-_25962291 2.05

chr9_+_54612545 2.04 ENSDART00000104475
tmsb4x
thymosin, beta 4 x
chr7_+_35769973 2.02 ENSDART00000168658
irx3a
iroquois homeobox 3a
chr2_-_42784609 2.01

chr22_-_336857 1.97

chr7_-_33678058 1.95 ENSDART00000173513
pias1a
protein inhibitor of activated STAT, 1a
chr12_+_23302859 1.94 ENSDART00000077732
bambia
BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a
chr15_-_18638643 1.93 ENSDART00000142010
ncam1b
neural cell adhesion molecule 1b
chr10_+_4987494 1.92 ENSDART00000121959
si:ch73-234b20.5
si:ch73-234b20.5
chr6_-_14821305 1.92

chr21_+_27346176 1.91 ENSDART00000005682
actn3a
actinin alpha 3a
chr23_+_10552781 1.90

chr5_-_32687349 1.89 ENSDART00000004238
rpl7a
ribosomal protein L7a
chr15_+_1187249 1.88 ENSDART00000152638
ENSDART00000152466
mlf1
myeloid leukemia factor 1
chr23_+_11412329 1.88 ENSDART00000135406
chl1a
cell adhesion molecule L1-like a
chr1_+_30992553 1.88 ENSDART00000112333
cnnm2b
cyclin and CBS domain divalent metal cation transport mediator 2b
chr16_+_26989962 1.87 ENSDART00000140673
galnt1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1
chr23_-_20332076 1.86 ENSDART00000147326
lamb2
laminin, beta 2 (laminin S)
chr12_-_3742062 1.85 ENSDART00000092983
ENSDARG00000063555
ENSDARG00000063555
chr6_+_30441419 1.79

chr14_-_27703812 1.77 ENSDART00000054115
tsc22d3
TSC22 domain family, member 3
chr5_+_44722544 1.74 ENSDART00000084411
adamts3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr14_-_26406720 1.74 ENSDART00000078563
neurog1
neurogenin 1
chr7_+_65532390 1.74 ENSDART00000156683
CT573494.2
ENSDARG00000097673
chr17_-_26849495 1.71 ENSDART00000153590
si:dkey-221l4.10
si:dkey-221l4.10
chr23_-_1008307 1.70 ENSDART00000110588
cdh26.1
cadherin 26, tandem duplicate 1
chr5_-_24568752 1.70 ENSDART00000145061
pnpla7b
patatin-like phospholipase domain containing 7b
chr13_-_37394157 1.69 ENSDART00000141420
sgpp1
sphingosine-1-phosphate phosphatase 1
chr23_-_29138952 1.68 ENSDART00000002812
casz1
castor zinc finger 1
chr1_+_45503061 1.68 ENSDART00000010894
sox1b
SRY (sex determining region Y)-box 1b
chr25_+_18467217 1.67 ENSDART00000170841
cav1
caveolin 1
chr11_+_27970922 1.64 ENSDART00000169360
ENSDART00000043756
ephb2b
eph receptor B2b
chr5_-_41672394 1.63 ENSDART00000164363
si:ch211-207c6.2
si:ch211-207c6.2
chr1_-_51086211 1.62 ENSDART00000045894
rnaseh2a
ribonuclease H2, subunit A
chr13_+_18414806 1.61 ENSDART00000110197
zgc:154058
zgc:154058
chr13_+_24703802 1.61 ENSDART00000101274
zgc:153981
zgc:153981
chr9_-_55204516 1.60

chr4_-_9779763 1.60 ENSDART00000134280
svopl
SVOP-like
chr19_+_20202737 1.54 ENSDART00000164677
hoxa4a
homeobox A4a
chr18_+_38768524 1.53 ENSDART00000143735
si:ch211-215d8.2
si:ch211-215d8.2
chr10_+_10393377 1.47 ENSDART00000109432
cercam
cerebral endothelial cell adhesion molecule
chr2_+_38057483 1.43 ENSDART00000159951
casq1a
calsequestrin 1a
chr12_-_36138709 1.42 ENSDART00000130985
st6galnac
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase
chr21_+_38770125 1.41 ENSDART00000149085
hnf1bb
HNF1 homeobox Bb
chr1_+_12076622 1.40 ENSDART00000159226
pcdh10a
protocadherin 10a
chr25_+_5922190 1.39 ENSDART00000128816
sv2
synaptic vesicle glycoprotein 2
chr11_+_24720057 1.37 ENSDART00000145647
sulf2a
sulfatase 2a
chr8_-_38308535 1.37

chr10_+_36861503 1.37 ENSDART00000153914
BX323076.1
ENSDARG00000097240
chr17_+_18097490 1.35 ENSDART00000144894
bcl11ba
B-cell CLL/lymphoma 11Ba (zinc finger protein)
chr24_-_25283218 1.34 ENSDART00000090010
phex
phosphate regulating endopeptidase homolog, X-linked
chr7_+_72257899 1.31

chr19_-_28273791 1.31 ENSDART00000137033
srd5a1
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
chr19_+_20183210 1.31 ENSDART00000164968
hoxa4a
homeobox A4a
chr12_-_34786844 1.30 ENSDART00000027379
bicral
BRD4 interacting chromatin remodeling complex associated protein like
chr22_-_337198 1.30

chr25_+_5162045 1.29 ENSDART00000169540
ENSDARG00000101164
ENSDARG00000101164
chr21_+_5887486 1.27 ENSDART00000048399
slc4a4b
solute carrier family 4 (sodium bicarbonate cotransporter), member 4b
chr13_+_41998500 1.26 ENSDART00000074707
cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr6_-_54103765 1.26 ENSDART00000083880
hyal2a
hyaluronoglucosaminidase 2a
chr2_-_30071872 1.25 ENSDART00000056747
shhb
sonic hedgehog b
KN150001v1_+_14939 1.22

chr12_+_30471689 1.21 ENSDART00000124920
nrap
nebulin-related anchoring protein
chr3_-_58488929 1.21 ENSDART00000042386
unm_sa1261
un-named sa1261
chr19_-_22182031 1.20 ENSDART00000104279
znf516
zinc finger protein 516
chr19_+_14669633 1.19 ENSDART00000022076
fam46bb
family with sequence similarity 46, member Bb
chr2_+_33399405 1.19 ENSDART00000137207
slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr5_-_57016269 1.19 ENSDART00000074264
crfb12
cytokine receptor family member B12
chr12_-_28766713 1.18 ENSDART00000148459
cbx1b
chromobox homolog 1b (HP1 beta homolog Drosophila)
chr16_+_53111969 1.17 ENSDART00000011506
nkd2b
naked cuticle homolog 2b
chr3_+_24145201 1.15 ENSDART00000169765
pdgfbb
platelet-derived growth factor beta polypeptide b
chr20_+_51388214 1.15 ENSDART00000153452
hsp90ab1
heat shock protein 90, alpha (cytosolic), class B member 1
chr3_-_5318289 1.15 ENSDART00000137105
myh9b
myosin, heavy chain 9b, non-muscle
chr20_+_28958586 1.13 ENSDART00000142678
slc10a1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr8_+_11604334 1.13 ENSDART00000004288
ift81
intraflagellar transport 81 homolog
chr16_+_12740993 1.13 ENSDART00000128497
nat14
N-acetyltransferase 14 (GCN5-related, putative)
chr23_-_4175790 1.10 ENSDART00000109807
ENSDARG00000076299
ENSDARG00000076299
chr21_+_5044859 1.10 ENSDART00000130569
st8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr11_+_19894772 1.10 ENSDART00000103997
fezf2
FEZ family zinc finger 2
chr21_+_44018278 1.09 ENSDART00000012396
ik
IK cytokine
chr19_-_30975279 1.08 ENSDART00000171006
hpcal4
hippocalcin like 4
chr12_-_3741925 1.08 ENSDART00000092983
ENSDARG00000063555
ENSDARG00000063555
chr5_-_62609495 1.08 ENSDART00000164651
gsnb
gelsolin b
chr4_-_16417703 1.08 ENSDART00000013085
dcn
decorin
chr5_+_58824344 1.07 ENSDART00000148727
gtf2ird1
GTF2I repeat domain containing 1
chr25_+_34135377 1.07 ENSDART00000157519
trpm1b
transient receptor potential cation channel, subfamily M, member 1b
chr2_+_10497066 1.06 ENSDART00000063996
gadd45aa
growth arrest and DNA-damage-inducible, alpha, a
chr15_-_47696481 1.05

chr16_-_20084451 1.05 ENSDART00000079155
hdac9b
histone deacetylase 9b
chr5_-_24806610 1.04 ENSDART00000089748
rorb
RAR-related orphan receptor B
chr19_+_42491631 1.04 ENSDART00000150949
nfyc
nuclear transcription factor Y, gamma
chr1_+_41523935 1.03 ENSDART00000110860
ctnna2
catenin (cadherin-associated protein), alpha 2
chr5_-_34393017 1.02 ENSDART00000134516
btf3
basic transcription factor 3
chr8_-_17031599 0.99 ENSDART00000132687
rab3c
RAB3C, member RAS oncogene family
chr22_-_336942 0.99

chr1_+_6995893 0.99 ENSDART00000163488
en1b
engrailed homeobox 1b
chr1_-_1254253 0.99 ENSDART00000130697
runx1
runt-related transcription factor 1
chr1_-_47080507 0.98 ENSDART00000101079
neurl1aa
neuralized E3 ubiquitin protein ligase 1Aa
chr20_+_51388313 0.97 ENSDART00000153452
hsp90ab1
heat shock protein 90, alpha (cytosolic), class B member 1
chr17_+_1986151 0.95 ENSDART00000103775
pak6a
p21 protein (Cdc42/Rac)-activated kinase 6a
chr5_-_24365811 0.95 ENSDART00000112287
gas2l1
growth arrest-specific 2 like 1
chr11_+_19894390 0.93 ENSDART00000103997
fezf2
FEZ family zinc finger 2
chr2_+_58658615 0.93

chr24_+_16992420 0.93

chr5_+_63103958 0.92

chr16_-_21064300 0.92 ENSDART00000040727
tax1bp1b
Tax1 (human T-cell leukemia virus type I) binding protein 1b
chr21_-_11554253 0.92 ENSDART00000133443
cast
calpastatin
chr25_-_35698109 0.92 ENSDART00000134928
nfatc3b
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3b
chr7_-_29300402 0.90 ENSDART00000099477
rorab
RAR-related orphan receptor A, paralog b
chr21_+_26696853 0.88 ENSDART00000168379
pcxa
pyruvate carboxylase a
chr6_+_4379989 0.87 ENSDART00000025031
pou4f1
POU class 4 homeobox 1
chr21_-_14276856 0.87

chr2_-_30071815 0.86 ENSDART00000056747
shhb
sonic hedgehog b
chr16_+_25158949 0.84 ENSDART00000155465
si:dkeyp-84f3.9
si:dkeyp-84f3.9
chr24_+_16249188 0.83 ENSDART00000164516
sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr16_+_21090083 0.82 ENSDART00000052662
hoxa13b
homeobox A13b
chr23_-_6831711 0.82 ENSDART00000125393
FP102169.1
ENSDARG00000089210
chr4_+_67023074 0.81 ENSDART00000158749
zgc:173702
zgc:173702
chr2_-_30071993 0.81 ENSDART00000056747
shhb
sonic hedgehog b
chr4_+_830826 0.80

chr4_+_9393501 0.80 ENSDART00000092013
tmtc1
transmembrane and tetratricopeptide repeat containing 1
chr11_-_35313757 0.80 ENSDART00000031441
sema3fb
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb
chr7_-_29300448 0.80 ENSDART00000019140
rorab
RAR-related orphan receptor A, paralog b
chr20_-_33272014 0.80 ENSDART00000178752
ENSDART00000047834
nbas
neuroblastoma amplified sequence
chr7_-_51186389 0.78 ENSDART00000174328
arhgap6
Rho GTPase activating protein 6
KN150001v1_+_15017 0.77

chr19_-_32454747 0.77 ENSDART00000088358
znf704
zinc finger protein 704
chr13_+_30820707 0.77 ENSDART00000057469
vstm4a
V-set and transmembrane domain containing 4a
chr13_+_49154065 0.77

chr3_-_45420882 0.77 ENSDART00000161507
zgc:153426
zgc:153426
chr23_-_2957203 0.76 ENSDART00000165955
zhx3
zinc fingers and homeoboxes 3
chr19_+_42491275 0.76

chr13_-_48465147 0.75 ENSDART00000132895
ntpcr
nucleoside-triphosphatase, cancer-related
chr12_-_31342432 0.75 ENSDART00000148603
acsl5
acyl-CoA synthetase long-chain family member 5
chr20_+_46309812 0.74 ENSDART00000100532
stx7l
syntaxin 7-like
chr23_+_16937788 0.72 ENSDART00000060181
zgc:114174
zgc:114174
chr20_+_25727285 0.72 ENSDART00000143883
ppat
phosphoribosyl pyrophosphate amidotransferase
chr2_-_59019569 0.72

chr7_-_67028394 0.71 ENSDART00000048104
znf143a
zinc finger protein 143a
chr3_+_41416821 0.70 ENSDART00000157023
card11
caspase recruitment domain family, member 11
chr2_+_52561735 0.70 ENSDART00000175043
CABZ01040021.1
ENSDARG00000107973
chr24_+_25326286 0.70 ENSDART00000066625
smpx
small muscle protein, X-linked
KN150460v1_+_164589 0.69

chr2_+_47864913 0.69

chr13_+_48565310 0.69

chr2_-_42784707 0.68

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.6 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.8 2.4 GO:0070254 mucus secretion(GO:0070254)
0.8 3.2 GO:0061072 iris morphogenesis(GO:0061072)
0.8 3.1 GO:0045168 cell-cell signaling involved in cell fate commitment(GO:0045168)
0.6 2.5 GO:0055016 hypochord development(GO:0055016)
0.6 3.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.6 2.3 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.6 3.3 GO:0003311 pancreatic D cell differentiation(GO:0003311) foregut morphogenesis(GO:0007440)
0.5 2.2 GO:1901052 sarcosine metabolic process(GO:1901052)
0.5 2.1 GO:1901389 transforming growth factor beta activation(GO:0036363) transforming growth factor beta production(GO:0071604) regulation of transforming growth factor beta production(GO:0071634) negative regulation of transforming growth factor beta production(GO:0071635) regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
0.5 3.2 GO:0071322 cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.5 4.6 GO:0072098 anterior/posterior pattern specification involved in pronephros development(GO:0034672) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.5 2.4 GO:0090527 actin filament reorganization(GO:0090527)
0.5 4.3 GO:2000047 regulation of cell-cell adhesion mediated by cadherin(GO:2000047)
0.5 1.4 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.4 1.7 GO:0021516 dorsal spinal cord development(GO:0021516)
0.3 5.9 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.3 2.4 GO:0060325 face morphogenesis(GO:0060325)
0.3 1.0 GO:0010712 regulation of collagen metabolic process(GO:0010712) regulation of granulocyte differentiation(GO:0030852) plasminogen activation(GO:0031639) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246) regulation of neutrophil differentiation(GO:0045658)
0.3 3.9 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.3 2.9 GO:0003348 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.3 2.2 GO:0036065 fucosylation(GO:0036065)
0.3 2.8 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.3 1.9 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.3 2.5 GO:0032048 cardiolipin metabolic process(GO:0032048) phosphatidylglycerol metabolic process(GO:0046471)
0.3 1.2 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.3 1.2 GO:0099565 chemical synaptic transmission, postsynaptic(GO:0099565)
0.3 1.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.3 0.8 GO:2000622 negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.3 1.0 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.2 0.7 GO:1903959 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) regulation of organic acid transport(GO:0032890) positive regulation of organic acid transport(GO:0032892) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transport(GO:1903793) regulation of anion transmembrane transport(GO:1903959) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.2 0.5 GO:0061323 cell proliferation involved in heart morphogenesis(GO:0061323) regulation of cell proliferation involved in heart morphogenesis(GO:2000136)
0.2 2.4 GO:0030216 keratinocyte differentiation(GO:0030216)
0.2 3.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.2 2.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.2 1.6 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.2 1.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.2 1.9 GO:0030168 platelet activation(GO:0030168)
0.2 0.6 GO:0070166 enamel mineralization(GO:0070166) amelogenesis(GO:0097186)
0.2 1.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 1.7 GO:0006670 sphingosine metabolic process(GO:0006670)
0.2 3.3 GO:0051764 actin crosslink formation(GO:0051764)
0.2 3.6 GO:0030199 collagen fibril organization(GO:0030199)
0.2 1.9 GO:0070831 basement membrane assembly(GO:0070831)
0.2 0.6 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.2 1.7 GO:0031641 regulation of myelination(GO:0031641)
0.2 2.2 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 1.1 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 1.4 GO:0097324 melanocyte migration(GO:0097324)
0.1 2.0 GO:0036302 atrioventricular canal development(GO:0036302)
0.1 1.1 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.1 1.1 GO:0048339 paraxial mesoderm development(GO:0048339)
0.1 0.5 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 1.0 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 1.3 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 3.4 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.1 1.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.8 GO:0010002 cardioblast differentiation(GO:0010002)
0.1 1.3 GO:0015701 bicarbonate transport(GO:0015701)
0.1 1.9 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.3 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.1 0.4 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.9 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 1.6 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 1.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.3 GO:1903306 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.1 0.6 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 1.1 GO:0050654 chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.1 2.0 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 0.5 GO:0090660 cerebrospinal fluid circulation(GO:0090660)
0.0 6.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.3 GO:0007548 sex differentiation(GO:0007548)
0.0 2.3 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 1.1 GO:0051014 actin filament severing(GO:0051014)
0.0 2.1 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.5 GO:0021508 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0 0.2 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.0 0.7 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 1.1 GO:0060402 cytosolic calcium ion transport(GO:0060401) calcium ion transport into cytosol(GO:0060402)
0.0 1.1 GO:0007599 blood coagulation(GO:0007596) hemostasis(GO:0007599)
0.0 1.0 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.3 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.7 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.8 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.7 GO:0048278 vesicle docking(GO:0048278)
0.0 0.1 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.5 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 1.6 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.2 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 5.7 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 0.6 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.6 GO:0010506 regulation of autophagy(GO:0010506)
0.0 1.7 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.1 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.0 0.8 GO:0033333 fin development(GO:0033333)
0.0 4.3 GO:0045892 negative regulation of transcription, DNA-templated(GO:0045892)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.3 GO:0016600 flotillin complex(GO:0016600)
0.8 2.4 GO:0098594 mucin granule(GO:0098594)
0.6 1.7 GO:0033270 paranode region of axon(GO:0033270)
0.3 1.0 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.3 1.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.3 1.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.2 2.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 4.4 GO:0045095 keratin filament(GO:0045095)
0.2 2.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 3.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 1.9 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.2 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.7 GO:0043034 costamere(GO:0043034)
0.1 2.9 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 0.5 GO:0005858 axonemal dynein complex(GO:0005858)
0.1 2.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 1.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 2.3 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 2.2 GO:0016342 catenin complex(GO:0016342)
0.1 2.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 1.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.4 GO:0005795 Golgi stack(GO:0005795)
0.0 0.4 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 1.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.1 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.4 GO:0014069 postsynaptic density(GO:0014069)
0.0 1.5 GO:0030018 Z disc(GO:0030018)
0.0 1.1 GO:0016459 myosin complex(GO:0016459)
0.0 4.7 GO:0043235 receptor complex(GO:0043235)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 2.9 GO:0005938 cell cortex(GO:0005938)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 7.7 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 1.9 GO:0016607 nuclear speck(GO:0016607)
0.0 1.3 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.8 GO:0030141 secretory granule(GO:0030141)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.6 2.5 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.6 3.6 GO:1901612 cardiolipin binding(GO:1901612)
0.5 1.4 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.4 1.3 GO:0035671 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.4 2.1 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.4 1.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.4 1.5 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.3 5.6 GO:0005112 Notch binding(GO:0005112)
0.3 2.9 GO:0005113 patched binding(GO:0005113)
0.3 1.1 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.3 1.9 GO:0061665 SUMO ligase activity(GO:0061665)
0.3 1.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 5.0 GO:0005518 collagen binding(GO:0005518)
0.2 1.7 GO:0070888 E-box binding(GO:0070888)
0.2 0.7 GO:0004044 amidophosphoribosyltransferase activity(GO:0004044)
0.2 1.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 2.4 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.2 0.7 GO:0050700 CARD domain binding(GO:0050700)
0.2 1.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 2.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 1.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 2.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.7 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 0.6 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 1.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 1.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 2.6 GO:0044325 ion channel binding(GO:0044325)
0.1 0.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 3.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.7 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.8 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.6 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 3.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.4 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 0.8 GO:0038191 neuropilin binding(GO:0038191)
0.1 3.2 GO:0045296 cadherin binding(GO:0045296)
0.1 1.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 1.8 GO:0005109 frizzled binding(GO:0005109)
0.0 1.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 2.7 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 1.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 3.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.7 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.3 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 1.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:0032977 membrane insertase activity(GO:0032977)
0.0 1.2 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 38.1 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 2.9 GO:0060090 binding, bridging(GO:0060090)
0.0 1.6 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.7 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 1.1 GO:0005262 calcium channel activity(GO:0005262)
0.0 2.6 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 3.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 5.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.2 1.7 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 3.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 3.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 1.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 2.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 4.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 2.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 PID ARF6 PATHWAY Arf6 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.3 2.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.3 2.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 1.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 4.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.1 REACTOME BILE ACID AND BILE SALT METABOLISM Genes involved in Bile acid and bile salt metabolism
0.1 1.0 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.1 0.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 2.4 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 2.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.7 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 2.7 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 2.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases