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Results for pou2f3

Z-value: 0.54

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Transcription factors associated with pou2f3

Gene Symbol Gene ID Gene Info
ENSDARG00000052387 POU class 2 homeobox 3

Activity profile of pou2f3 motif

Sorted Z-values of pou2f3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of pou2f3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_+_13118866 0.84 ENSDART00000123257
MAP kinase interacting serine/threonine kinase 1
chr8_-_14014576 0.76 ENSDART00000135811
ATPase, Ca++ transporting, plasma membrane 3a
chr21_+_36938230 0.58 ENSDART00000027459
G protein-coupled receptor kinase 6
chr10_-_22881453 0.57

chr14_+_14850200 0.53 ENSDART00000167966
zgc:158852
chr9_+_34510091 0.53 ENSDART00000035522
ENSDART00000170615
ENSDART00000146480
POU class 2 homeobox 1b
chr9_+_49961721 0.46

chr10_+_26636293 0.44 ENSDART00000079187
four and a half LIM domains 1b
chr3_-_59690168 0.42 ENSDART00000035878
cerebellar degeneration-related protein 2-like
chr20_+_54525614 0.41 ENSDART00000160409
ADP-ribosylation factor 6a
chr16_+_4292625 0.41

chr10_-_45535333 0.39

chr19_-_5186692 0.38 ENSDART00000037007
triosephosphate isomerase 1a
chr13_-_2211438 0.38 ENSDART00000137124
ARFGEF family member 3
chr11_+_30416953 0.37

chr16_+_46145286 0.37 ENSDART00000172232
synaptic vesicle glycoprotein 2A
chr19_-_5429428 0.36 ENSDART00000066620
ENSDART00000151398
keratin type 1 c19e
chr4_+_30530 0.35 ENSDART00000157825
synapsin III
chr10_+_2554651 0.34 ENSDART00000016103
nucleoredoxin-like 2
chr18_+_5303006 0.34

chr3_-_48458042 0.33 ENSDART00000156822
cell death-inducing p53 target 1
chr10_+_15450466 0.33 ENSDART00000003839
neurolysin (metallopeptidase M3 family)
chr8_-_7584890 0.33 ENSDART00000137975
interleukin-1 receptor-associated kinase 1
chr9_+_30297924 0.32 ENSDART00000060174
jagunal homolog 1a
chr10_-_14971401 0.32 ENSDART00000044756
ENSDART00000128579
SMAD family member 2
chr13_+_22346304 0.32 ENSDART00000137220
LIM domain binding 3a
chr1_-_50395003 0.30 ENSDART00000035150
spastin
chr5_-_47523737 0.30 ENSDART00000153239
ENSDARG00000095715
chr20_-_43853614 0.29 ENSDART00000100605
tetratricopeptide repeat domain 32
chr5_-_19459698 0.29 ENSDART00000148146
si:dkey-234h16.7
chr5_-_15921657 0.29

chr18_+_31038010 0.28 ENSDART00000163471
urate (5-hydroxyiso-) hydrolase a
chr20_+_54525159 0.28 ENSDART00000160409
ADP-ribosylation factor 6a
chr7_-_17916122 0.28 ENSDART00000127428
pellino E3 ubiquitin protein ligase family member 3
chr21_+_34053590 0.28 ENSDART00000147519
ENSDART00000158115
ENSDART00000029599
ENSDART00000145123
myotubularin related protein 1b
chr14_-_3937426 0.27 ENSDART00000169527
sorting nexin 25
chr11_+_11000566 0.27 ENSDART00000065933
integrin, beta 6
chr19_+_1743359 0.27 ENSDART00000166744
DENN/MADD domain containing 3a
chr24_-_20496410 0.26 ENSDART00000166135
zinc finger and BTB domain containing 47b
chr9_+_12473243 0.26 ENSDART00000132709
transmembrane protein 41aa
chr5_+_23741791 0.26 ENSDART00000049003
ATPase, H+ transporting, lysosomal, V1 subunit Aa
chr11_+_43136945 0.26

chr18_-_20880226 0.25 ENSDART00000090079
synemin, intermediate filament protein
chr20_-_54669179 0.25

chr6_+_4091120 0.25 ENSDART00000170351
neurobeachin-like 1
chr10_-_22948684 0.25 ENSDART00000163908
ribonuclease, RNase K b
chr16_-_12282596 0.25 ENSDART00000110567
calsyntenin 3
chr10_-_34058331 0.24 ENSDART00000046599
zygote arrest 1-like
chr16_+_2582656 0.24 ENSDART00000092299
ENSDARG00000073784
chr10_+_9762039 0.24

chr13_-_39033849 0.24 ENSDART00000045434
collagen, type IX, alpha 1b
chr25_-_2932820 0.24 ENSDART00000149117
ENSDART00000137950
si:ch1073-296i8.2
chr25_-_24960874 0.24 ENSDART00000178891
ENSDARG00000061421
chr22_+_35299551 0.23 ENSDART00000165353
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr16_-_43107682 0.23 ENSDART00000142003
nudix (nucleoside diphosphate linked moiety X)-type motif 17
chr3_+_18645970 0.23 ENSDART00000042368
fumarylacetoacetate hydrolase domain containing 1
chr16_-_33637966 0.22 ENSDART00000142965
ENSDARG00000092272
chr5_-_64983812 0.22 ENSDART00000147707
calmodulin regulated spectrin-associated protein 1b
chr20_+_54595334 0.22

chr8_+_22910147 0.22 ENSDART00000063096
synaptophysin a
chr1_+_51087450 0.22 ENSDART00000040397
peroxiredoxin 2
chr10_+_2554914 0.22 ENSDART00000016103
nucleoredoxin-like 2
chr5_-_34364552 0.22 ENSDART00000133170
Rho guanine nucleotide exchange factor (GEF) 28
chr10_-_36849596 0.22

chr11_-_37613237 0.22 ENSDART00000102868
ethanolamine kinase 2
chr5_-_23741221 0.22 ENSDART00000042481
PHD finger protein 23a
chr22_+_18364282 0.21 ENSDART00000088270
YjeF N-terminal domain containing 3
chr23_-_18131105 0.21 ENSDART00000173102
zgc:92287
chr19_+_2942092 0.21 ENSDART00000177848
ENSDARG00000107451
chr7_+_10792973 0.21

chr18_+_3482740 0.21 ENSDART00000158763
leucine-rich repeats and calponin homology (CH) domain containing 3
chr19_+_2942485 0.21 ENSDART00000177848
ENSDARG00000107451
chr21_-_40694583 0.21 ENSDART00000045124
proteasome maturation protein
chr18_+_1347470 0.21

chr3_+_39425125 0.21 ENSDART00000146867
aldolase a, fructose-bisphosphate, a
chr13_+_42276937 0.21

chr8_-_53584884 0.20

chr24_-_25283218 0.20 ENSDART00000090010
phosphate regulating endopeptidase homolog, X-linked
chr17_-_37447869 0.20 ENSDART00000148160
cysteine-rich protein 1
chr9_+_3416525 0.20 ENSDART00000019910
distal-less homeobox 1a
chr23_-_33783345 0.20 ENSDART00000143333
POU class 6 homeobox 1
chr19_+_2942373 0.20 ENSDART00000177848
ENSDARG00000107451
chr20_-_39886349 0.20 ENSDART00000098253
ring finger protein 217
chr23_+_21546553 0.20 ENSDART00000142921
si:ch73-21g5.7
chr14_-_43191278 0.19 ENSDART00000169615
alcohol dehydrogenase 5
chr21_+_26035166 0.19 ENSDART00000134939
ribosomal protein L23a
chr25_-_36678227 0.19 ENSDART00000087247
golgi glycoprotein 1a
chr23_-_27418761 0.19 ENSDART00000022042
sodium channel, voltage gated, type VIII, alpha subunit a
chr10_+_23090883 0.19 ENSDART00000079711
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1a
chr11_-_41798903 0.19 ENSDART00000162944
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr10_-_42302932 0.19 ENSDART00000076693
ENSDART00000073631
STAM binding protein a
chr24_-_32864493 0.19

chr13_+_25590508 0.19 ENSDART00000046050
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
chr17_-_29196678 0.18 ENSDART00000076481
EH-domain containing 4
chr17_-_30958965 0.18 ENSDART00000051697
Enah/Vasp-like a
chr11_+_30400284 0.18 ENSDART00000169833
expressed sequence EH507706
chr11_+_36147478 0.18 ENSDART00000077641
cytochrome b561 family, member D1
chr1_-_18581114 0.18 ENSDART00000178278
ENSDARG00000107606
chr4_-_1952230 0.18 ENSDART00000135749
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr20_-_1248089 0.18 ENSDART00000027119
large tumor suppressor kinase 1
chr15_-_12297979 0.18 ENSDART00000165159
Down syndrome cell adhesion molecule like 1
chr23_-_25871518 0.17 ENSDART00000041833
fat storage-inducing transmembrane protein 2
chr1_-_9256864 0.17 ENSDART00000041849
transmembrane protein 8A
chr2_+_35258438 0.17 ENSDART00000015827
tenascin R (restrictin, janusin)
chr5_-_18393705 0.17 ENSDART00000010101
ENSDART00000099434
acetoacetyl-CoA synthetase
chr12_-_26317480 0.17 ENSDART00000105636
myozenin 1b
chr5_-_12706441 0.17 ENSDART00000051666
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr13_+_36832145 0.17 ENSDART00000024386
FERM domain containing 6
chr10_+_18953671 0.17 ENSDART00000135786
BCL2/adenovirus E1B interacting protein 3-like b
chr5_+_50580190 0.17 ENSDART00000083340
UBA domain containing 1
chr17_-_37447917 0.16 ENSDART00000075975
cysteine-rich protein 1
chr9_-_9000604 0.16 ENSDART00000145266
inhibitor of growth family, member 1
chr14_-_34172522 0.16 ENSDART00000140368
si:ch211-232m8.3
chr22_-_800449 0.16 ENSDART00000123487
zgc:153675
chr19_+_4835526 0.16

chr6_-_3837294 0.16 ENSDART00000059212
unc-50 homolog (C. elegans)
chr23_-_34967879 0.16 ENSDART00000168731
ENSDARG00000061272
chr17_+_11921705 0.16 ENSDART00000155329
consortin, connexin sorting protein a
chr5_-_47523636 0.16 ENSDART00000153239
ENSDARG00000095715
chr20_+_27565701 0.16

chr8_+_28891430 0.16 ENSDART00000141634
glutamate receptor, ionotropic, delta 2
chr9_-_32348003 0.16 ENSDART00000037182
ankyrin repeat domain 44
chr4_+_4501129 0.15 ENSDART00000028694
glucosamine (N-acetyl)-6-sulfatase a
chr20_-_35567985 0.15 ENSDART00000016090
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr5_+_38903966 0.15 ENSDART00000121460
PR domain containing 8b
chr9_-_32347940 0.15 ENSDART00000037182
ankyrin repeat domain 44
chr20_-_3074186 0.15 ENSDART00000046641
mitogen-activated protein kinase kinase kinase 5
chr9_-_6402663 0.15 ENSDART00000078523
esophageal cancer related gene 4a
chr20_-_31594202 0.15 ENSDART00000046841
SAM and SH3 domain containing 1a
chr10_+_18953548 0.15 ENSDART00000030205
BCL2/adenovirus E1B interacting protein 3-like b
chr20_+_40247918 0.15 ENSDART00000121818
triadin
chr12_+_48497255 0.15 ENSDART00000168389
Rho GTPase activating protein 44
chr12_+_44829938 0.14 ENSDART00000098932
WW domain binding protein 2
chr10_+_20222743 0.14 ENSDART00000167008
protein phosphatase 3, catalytic subunit, gamma isozyme, b
chr9_+_38672040 0.14 ENSDART00000157556
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr24_-_20496308 0.14 ENSDART00000166135
zinc finger and BTB domain containing 47b
chr16_+_53438411 0.14 ENSDART00000155940
ENSDARG00000097164
chr21_-_3462128 0.14 ENSDART00000139194
dymeclin
chr24_-_24859334 0.14 ENSDART00000080997
zinc finger, DHHC-type containing 20b
chr18_+_6747156 0.14 ENSDART00000111343
lipase maturation factor 2a
chr17_-_6294409 0.14 ENSDART00000064700
fucosidase, alpha-L- 2, plasma
chr5_-_64983964 0.14 ENSDART00000147707
calmodulin regulated spectrin-associated protein 1b
chr10_+_40293111 0.14

chr7_+_5855024 0.14 ENSDART00000173105
si:dkey-23a13.21
chr6_-_10728582 0.14 ENSDART00000151102
notum pectinacetylesterase 2
chr25_-_13394261 0.14 ENSDART00000056721
lactate dehydrogenase D
chr20_+_29788065 0.13 ENSDART00000164121
membrane bound O-acyltransferase domain containing 2b
chr20_+_4000402 0.13 ENSDART00000112053
family with sequence similarity 89, member A
chr6_+_7165326 0.13 ENSDART00000065500
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
chr22_-_20899539 0.13 ENSDART00000100642
elongation factor RNA polymerase II
chr9_-_14172110 0.13 ENSDART00000108950
tubulin tyrosine ligase-like family, member 4
chr3_-_14981512 0.13 ENSDART00000131720
exportin 6
chr19_+_5399535 0.13 ENSDART00000145749
si:dkeyp-113d7.1
chr14_-_34172619 0.13 ENSDART00000147380
ENSDARG00000092889
chr20_-_7186902 0.13 ENSDART00000012247
24-dehydrocholesterol reductase
chr19_-_26188624 0.13 ENSDART00000052393
par-6 family cell polarity regulator gamma b
chr10_-_36849540 0.13

chr25_-_20568599 0.13 ENSDART00000098076
c-src tyrosine kinase
chr19_-_33356861 0.13 ENSDART00000137611
antizyme inhibitor 1b
chr17_-_5918853 0.13 ENSDART00000058890
ENSDART00000171084
epoxide hydrolase 2, cytoplasmic
chr1_-_53123905 0.13 ENSDART00000122445
v-akt murine thymoma viral oncogene homolog 3b
chr14_+_49875056 0.12 ENSDART00000167810
zgc:154054
chr13_-_36495730 0.12 ENSDART00000165629
cyclin-dependent kinase inhibitor 3
chr23_+_22857958 0.12 ENSDART00000111345
arginine-glutamic acid dipeptide (RE) repeats a
chr18_+_6664159 0.12

chr4_+_12293403 0.12 ENSDART00000061070
makorin, ring finger protein, 1
chr22_+_28496424 0.12 ENSDART00000089546
ABI family, member 3 (NESH) binding protein b
chr5_-_11471707 0.12 ENSDART00000166285
si:ch73-47f2.1
chr8_-_17031599 0.12 ENSDART00000132687
RAB3C, member RAS oncogene family
chr17_-_7194180 0.12 ENSDART00000098731
syntaxin binding protein 5b (tomosyn)
chr16_+_17762256 0.12 ENSDART00000128672
transmembrane protein 238b
chr23_-_18131038 0.12 ENSDART00000173385
zgc:92287
chr7_+_55332040 0.12 ENSDART00000171736
trafficking protein particle complex 2-like
chr25_+_6059393 0.12 ENSDART00000154658
ornithine decarboxylase antizyme 2a
chr3_-_39163141 0.12 ENSDART00000102674
ENSDART00000167070
phospholipase C, delta 3a
chr14_-_2288186 0.12 ENSDART00000081870
protocadherin 2 alpha b 6
chr8_-_1833095 0.12 ENSDART00000114476
ENSDART00000091235
ENSDART00000140077
phosphatidylinositol 4-kinase, catalytic, alpha b
chr13_-_2083873 0.12 ENSDART00000129773
muscular LMNA-interacting protein
chr12_-_3630622 0.12 ENSDART00000164707
cytochrome C oxidase assembly factor 3a
chr18_-_35861482 0.12 ENSDART00000088488
optic atrophy 3
chr21_+_36938203 0.11 ENSDART00000027459
G protein-coupled receptor kinase 6
chr1_+_53294559 0.11 ENSDART00000159900
centriole, cilia and spindle-associated protein a
chr25_+_34410718 0.11 ENSDART00000073441
syntrophin, beta 2
chr12_-_48092534 0.11

chr2_-_14757989 0.11 ENSDART00000162816
ENSDARG00000099630
chr7_-_52678749 0.11 ENSDART00000174329
tubulin, gamma complex associated protein 4
chr13_-_46423391 0.11

chr6_+_4091251 0.11 ENSDART00000170351
neurobeachin-like 1
chr5_-_12706568 0.11 ENSDART00000051666
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr12_-_34786663 0.11 ENSDART00000158848
BRD4 interacting chromatin remodeling complex associated protein like
chr3_+_44328013 0.11 ENSDART00000166294
meteorin, glial cell differentiation regulator-like
chr25_-_10992022 0.11 ENSDART00000154748
synaptic vesicle glycoprotein 2Bb
chr9_-_33116897 0.11

chr19_-_1002877 0.11

chr16_+_53438473 0.11 ENSDART00000155940
ENSDARG00000097164
chr5_-_23741334 0.11 ENSDART00000042481
PHD finger protein 23a
chr5_+_59394192 0.10

chr17_+_21944679 0.10 ENSDART00000063704
cysteine-rich protein 3
chr18_+_31020260 0.10 ENSDART00000154993
CD151 antigen, like
chr5_+_26804676 0.10 ENSDART00000121886
ENSDART00000005025
hematopoietic death receptor

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.4 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 0.3 GO:1903523 negative regulation of heart contraction(GO:0045822) negative regulation of blood circulation(GO:1903523)
0.1 0.6 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.7 GO:0036010 protein localization to endosome(GO:0036010)
0.1 0.3 GO:1902869 negative regulation of photoreceptor cell differentiation(GO:0046533) regulation of amacrine cell differentiation(GO:1902869) positive regulation of amacrine cell differentiation(GO:1902871)
0.1 0.3 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.1 0.2 GO:0072526 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.1 0.3 GO:0043243 positive regulation of protein complex disassembly(GO:0043243)
0.1 0.3 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.3 GO:0050832 neutrophil mediated immunity(GO:0002446) defense response to fungus(GO:0050832)
0.1 0.2 GO:0086010 mechanosensory behavior(GO:0007638) membrane depolarization during action potential(GO:0086010)
0.1 0.2 GO:0046887 positive regulation of peptide secretion(GO:0002793) positive regulation of insulin secretion(GO:0032024) positive regulation of hormone secretion(GO:0046887) positive regulation of peptide hormone secretion(GO:0090277)
0.1 0.4 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.2 GO:1990697 protein depalmitoleylation(GO:1990697)
0.0 0.2 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.1 GO:1902269 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.1 GO:0051899 membrane depolarization(GO:0051899)
0.0 0.2 GO:0051965 regulation of synapse assembly(GO:0051963) positive regulation of synapse assembly(GO:0051965)
0.0 0.2 GO:0046294 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.0 0.6 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.4 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.2 GO:0032371 regulation of sterol transport(GO:0032371) regulation of cholesterol transport(GO:0032374)
0.0 0.1 GO:0031100 organ regeneration(GO:0031100)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.2 GO:0098869 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.1 GO:1902868 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.0 0.1 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.2 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.0 0.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0032978 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.0 0.1 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.1 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 0.2 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.1 GO:0071543 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.1 GO:0098754 detoxification(GO:0098754)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.3 GO:0072523 purine-containing compound catabolic process(GO:0072523)
0.0 0.1 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.2 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.2 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.1 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.2 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.3 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.8 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.2 GO:0001966 thigmotaxis(GO:0001966)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0046620 regulation of organ growth(GO:0046620)
0.0 0.2 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0002429 immune response-activating cell surface receptor signaling pathway(GO:0002429)
0.0 0.1 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.0 0.8 GO:0006836 neurotransmitter transport(GO:0006836)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 1.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.1 GO:1990879 CST complex(GO:1990879)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.3 GO:0030496 midbody(GO:0030496)
0.0 0.1 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 0.7 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.3 GO:0033971 hydroxyisourate hydrolase activity(GO:0033971)
0.1 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.2 GO:1903231 mRNA binding involved in posttranscriptional gene silencing(GO:1903231)
0.1 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.2 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 0.2 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.1 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0016803 ether hydrolase activity(GO:0016803)
0.0 0.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.1 GO:0052834 inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.4 GO:0044325 ion channel binding(GO:0044325)
0.0 0.3 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.2 GO:0017075 syntaxin-1 binding(GO:0017075)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.8 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.2 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 0.8 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport