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Results for pou3f2a+pou3f2b+pou3f3a+pou3f3b

Z-value: 1.00

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Transcription factors associated with pou3f2a+pou3f2b+pou3f3a+pou3f3b

Gene Symbol Gene ID Gene Info
ENSDARG00000042032 POU class 3 homeobox 3a
ENSDARG00000070220 POU class 3 homeobox 2a
ENSDARG00000076262 POU class 3 homeobox 2b
ENSDARG00000095896 POU class 3 homeobox 3b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou3f2adr10_dc_chr4_+_5733160_5733232-0.844.9e-05Click!
pou3f2bdr10_dc_chr16_+_32605735_32605856-0.837.4e-05Click!
pou3f3bdr10_dc_chr6_+_14823185_14823275-0.821.0e-04Click!
pou3f3adr10_dc_chr9_-_6683651_6683699-0.731.4e-03Click!

Activity profile of pou3f2a+pou3f2b+pou3f3a+pou3f3b motif

Sorted Z-values of pou3f2a+pou3f2b+pou3f3a+pou3f3b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of pou3f2a+pou3f2b+pou3f3a+pou3f3b

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr14_+_34150130 2.30 ENSDART00000132193
ENSDART00000141058
wingless-type MMTV integration site family, member 8a
ENSDARG00000105311
chr17_+_10582214 2.07 ENSDART00000051527
TATA box binding protein like 2
chr2_-_2373601 1.77 ENSDART00000113774
si:ch211-188c16.1
chr13_+_35799681 1.70 ENSDART00000046115
major facilitator superfamily domain containing 2aa
chr13_+_35799602 1.62 ENSDART00000046115
major facilitator superfamily domain containing 2aa
chr20_+_34091702 1.58 ENSDART00000061729
si:dkey-97o5.1
chr20_-_9135267 1.57 ENSDART00000125133
Myb-like, SWIRM and MPN domains 1
chr1_-_54391298 1.55 ENSDART00000152143
ENSDART00000152590
pellino E3 ubiquitin protein ligase 1a
chr10_-_7513764 1.53 ENSDART00000167054
ENSDART00000167706
neuregulin 1
chr24_+_34183462 1.51 ENSDART00000143995
zgc:92591
chr1_-_8593850 1.49 ENSDART00000146065
ENSDART00000114876
ubinuclein 1
chr14_-_33641145 1.47 ENSDART00000167774
forkhead box A sequence
chr7_-_8466131 1.46 ENSDART00000065488
testis expressed 261
chr1_+_13244145 1.43 ENSDART00000157563
nocturnin b
chr24_-_36413059 1.40 ENSDART00000062736
CoA synthase
chr7_-_5253629 1.39 ENSDART00000033316
VANGL planar cell polarity protein 2
chr8_-_49227232 1.36

chr25_+_5845303 1.35 ENSDART00000163948
ENSDARG00000053246
chr5_+_26888744 1.32 ENSDART00000123635
secreted frizzled-related protein 1a
chr6_+_28218420 1.27 ENSDART00000171216
ENSDART00000171377
si:ch73-14h10.2
chr3_+_32617947 1.27 ENSDART00000125260
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase
chr8_-_49227286 1.20

chr24_+_10758290 1.18 ENSDART00000106272
si:dkey-37o8.1
chr3_+_32285237 1.17 ENSDART00000157324
proline rich Gla (G-carboxyglutamic acid) 2
chr24_+_34183557 1.16 ENSDART00000143995
zgc:92591
chr11_+_39664664 1.16 ENSDART00000102734
ENSDART00000137516
vesicle-associated membrane protein 3 (cellubrevin)
chr1_-_39141284 1.16 ENSDART00000053763
dCMP deaminase
chr15_+_14656645 1.15 ENSDART00000162350
F-box protein 46
chr17_+_24790812 1.14 ENSDART00000082251
speedy/RINGO cell cycle regulator family member A
chr22_+_15317622 1.13 ENSDART00000045682
ribosomal RNA processing 36
chr24_-_25297360 1.12 ENSDART00000138215
phosphate regulating endopeptidase homolog, X-linked
chr1_+_13244109 1.12 ENSDART00000157563
nocturnin b
chr21_+_22598805 1.12 ENSDART00000142495
ENSDARG00000089088
chr16_-_33047066 1.12 ENSDART00000147941
ENSDART00000075218
malic enzyme 1, NADP(+)-dependent, cytosolic
chr3_+_40654510 1.11 ENSDART00000014729
actin related protein 2/3 complex, subunit 1A
chr24_-_36412892 1.10 ENSDART00000148868
CoA synthase
chr17_+_24791024 1.09 ENSDART00000130871
speedy/RINGO cell cycle regulator family member A
chr9_-_7308912 1.08 ENSDART00000128352
MIT, microtubule interacting and transport, domain containing 1
chr23_+_46000362 1.07 ENSDART00000023944
lamin L3
chr16_-_47446494 1.06 ENSDART00000032188
si:dkey-256h2.1
chr19_+_20617380 1.04 ENSDART00000133633
insulin-like growth factor 2 mRNA binding protein 3
chr2_-_47766563 1.04 ENSDART00000038228
adaptor-related protein complex 1, sigma 3 subunit, b
chr2_-_3588636 1.04 ENSDART00000055618
IBA57 homolog, iron-sulfur cluster assembly
chr18_+_8959686 1.03 ENSDART00000145226
si:ch211-233h19.2
chr7_+_38444768 1.02 ENSDART00000024590
synaptotagmin XIII
chr18_+_27457678 1.01 ENSDART00000014726
tumor protein p53 inducible protein 11b
chr5_-_39205454 0.98 ENSDART00000133231
RasGEF domain family, member 1Ba
chr15_-_5913264 0.97 ENSDART00000155156
ENSDART00000155971
si:ch73-281n10.2
chr11_+_34909393 0.96 ENSDART00000110839
MON1 secretory trafficking family member A
chr15_+_14656797 0.96 ENSDART00000162350
F-box protein 46
chr18_+_6747156 0.95 ENSDART00000111343
lipase maturation factor 2a
chr2_+_15379717 0.95 ENSDART00000058484
calponin 3, acidic b
chr3_-_20912934 0.95 ENSDART00000156275
family with sequence similarity 57, member Ba
chr21_+_19040595 0.95 ENSDART00000145969
ENSDARG00000092282
chr9_+_23813071 0.95

chr10_-_21404605 0.95 ENSDART00000125167
avidin
chr18_+_15137751 0.94 ENSDART00000168639
cryptochrome circadian clock 1ab
chr14_+_9175399 0.94 ENSDART00000054690
ENSDART00000135449
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr19_+_33551956 0.94 ENSDART00000043039
family with sequence similarity 84, member B
chr2_-_26941084 0.93 ENSDART00000134685
ENSDART00000056787
zgc:113691
chr2_-_26941232 0.93 ENSDART00000134685
ENSDART00000056787
zgc:113691
chr21_-_30247820 0.92 ENSDART00000066363
ENSDARG00000045127
chr13_+_11696495 0.92 ENSDART00000110141
suppressor of fused homolog (Drosophila)
chr17_+_4902984 0.92 ENSDART00000064313
ENSDART00000121806
CDC5 cell division cycle 5-like (S. pombe)
chr20_+_51193122 0.91 ENSDART00000028084
membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5)
chr24_-_6304289 0.91 ENSDART00000140212
zgc:174877
chr16_+_53632289 0.91 ENSDART00000124691
sphingomyelin phosphodiesterase 5
chr3_-_33296077 0.91 ENSDART00000075495
ribosomal protein L23
chr13_-_17991273 0.91 ENSDART00000128748
family with sequence similarity 21, member C
chr15_+_20054306 0.90 ENSDART00000155199
zgc:112083
chr4_+_20074260 0.90 ENSDART00000024925
GRIP and coiled-coil domain containing 1
chr14_+_25208174 0.90 ENSDART00000079016
THO complex 3
chr25_+_7067115 0.89 ENSDART00000179500
ENSDARG00000107609
chr5_-_37785264 0.87

chr24_+_21030141 0.87 ENSDART00000154940
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr25_-_3619590 0.86 ENSDART00000037973
MORC family CW-type zinc finger 2
chr7_-_8465988 0.85 ENSDART00000172928
testis expressed 261
chr25_+_33118422 0.85

chr23_+_44470297 0.85 ENSDART00000149842
methylphosphate capping enzyme
chr13_-_49749441 0.84 ENSDART00000136165
lysosomal trafficking regulator
chr21_+_6008781 0.84 ENSDART00000141607
folylpolyglutamate synthase
chr1_-_8843231 0.84 ENSDART00000110790
si:ch73-12o23.1
chr19_+_20617246 0.83 ENSDART00000133633
insulin-like growth factor 2 mRNA binding protein 3
chr22_+_8856370 0.83 ENSDART00000178799
ENSDARG00000109049
chr2_-_6153363 0.83 ENSDART00000037698
uridine-cytidine kinase 2b
chr12_+_31345948 0.82 ENSDART00000031154
guanylate cyclase 2g
chr1_-_22617455 0.82 ENSDART00000137567
small integral membrane protein 14
chr23_-_3568408 0.82 ENSDART00000019667
ring finger protein 114
chr19_+_7489293 0.82 ENSDART00000081746
apolipoprotein A-I binding protein
chr2_+_30497550 0.81 ENSDART00000125933
family with sequence similarity 173, member B
chr1_+_48770997 0.81 ENSDART00000015007
TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr24_+_36451347 0.81 ENSDART00000142264
granulin b
chr8_-_22493608 0.81 ENSDART00000021514
APEX nuclease (apurinic/apyrimidinic endonuclease) 2
chr14_+_29932533 0.81 ENSDART00000017122
N-acylsphingosine amidohydrolase (acid ceramidase) 1a
chr17_-_49980590 0.80 ENSDART00000106562
zgc:113886
chr5_+_29193876 0.80 ENSDART00000045410
Thy-1 cell surface antigen
chr8_-_28323975 0.79

chr3_+_54551887 0.79 ENSDART00000169663
ENSDARG00000098327
chr20_+_31036284 0.79 ENSDART00000153344
superoxide dismutase 2, mitochondrial
chr3_+_37648476 0.79 ENSDART00000151506
si:dkey-260c8.8
chr3_+_32617855 0.79 ENSDART00000053684
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase
chr25_+_2252667 0.78 ENSDART00000172905
zmp:0000000932
chr9_-_21287478 0.77 ENSDART00000018570
tryptophanyl tRNA synthetase 2, mitochondrial
chr9_-_34700736 0.77 ENSDART00000169114
protein phosphatase 2, regulatory subunit B'', beta
chr2_-_37299150 0.76 ENSDART00000137598
NAD kinase b
chr10_+_10429005 0.76 ENSDART00000129253
ENSDART00000131043
sarcosine dehydrogenase
chr25_-_36512943 0.76 ENSDART00000114508
hypoxanthine phosphoribosyltransferase 1, like
chr17_+_13803088 0.76 ENSDART00000176632
ENSDARG00000107833
chr2_-_19705537 0.76 ENSDART00000168627
zinc finger, FYVE domain containing 9a
chr1_-_8842947 0.75 ENSDART00000110790
si:ch73-12o23.1
chr17_-_27217309 0.75 ENSDART00000130080
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr23_-_17503357 0.75 ENSDART00000043076
pancreatic progenitor cell differentiation and proliferation factor b
chr18_-_7138171 0.74 ENSDART00000149122
cilia and flagella associated protein 161
chr3_+_17783319 0.74 ENSDART00000104299
2',3'-cyclic nucleotide 3' phosphodiesterase
chr13_+_35799851 0.74 ENSDART00000046115
major facilitator superfamily domain containing 2aa
chr13_-_50940551 0.74

chr17_-_18878230 0.73 ENSDART00000028044
galactosylceramidase b
chr23_-_41367783 0.73

chr5_-_8177663 0.73 ENSDART00000168659
zgc:153352
chr17_-_23234771 0.73

chr13_+_29795813 0.73 ENSDART00000131609
CUE domain containing 2
chr2_+_15379961 0.72 ENSDART00000058484
calponin 3, acidic b
chr18_+_15137711 0.72 ENSDART00000128609
cryptochrome circadian clock 1ab
chr8_+_2484943 0.72 ENSDART00000101137
GLE1 RNA export mediator homolog (yeast)
chr14_-_16469435 0.72 ENSDART00000113711
zgc:123335
chr25_-_14684924 0.72

chr20_-_23354440 0.71 ENSDART00000103365
OCIA domain containing 1
chr16_-_52090636 0.71 ENSDART00000155308
ENSDARG00000063300
chr21_-_31215463 0.71 ENSDART00000170507
calcitonin gene-related peptide-receptor component protein
chr23_-_27768575 0.71 ENSDART00000146703
IKAROS family zinc finger 4
chr2_-_37116119 0.71 ENSDART00000003670
zgc:101744
chr13_+_51747107 0.70 ENSDART00000161098
lysocardiolipin acyltransferase 1
chr5_+_36049836 0.70 ENSDART00000147667
alkB homolog 6
chr12_-_26529300 0.69 ENSDART00000162163
ENSDART00000087067
hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing
chr4_-_24033285 0.69 ENSDART00000132855
carboxypeptidase M
chr15_-_25333252 0.69 ENSDART00000127771
methyltransferase like 16
chr10_+_44456550 0.69 ENSDART00000157611
small nuclear ribonucleoprotein 35 (U11/U12)
chr4_-_20119812 0.69 ENSDART00000100867
family with sequence similarity 3, member C
chr24_+_29902165 0.69 ENSDART00000168422
ENSDART00000100092
ENSDART00000113304
ferric-chelate reductase 1b
chr7_-_38443332 0.68 ENSDART00000047220
F-box protein 3
chr2_-_26940965 0.68 ENSDART00000134685
ENSDART00000056787
zgc:113691
chr7_-_15008685 0.68 ENSDART00000173048
ENSDARG00000023868
chr14_+_9175488 0.67 ENSDART00000054690
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr2_-_44123230 0.67

chr19_+_27338879 0.67 ENSDART00000149988
negative elongation factor complex member E
chr11_+_30006715 0.67 ENSDART00000157272
ENSDART00000003475
protein phosphatase, EF-hand calcium binding domain 1
chr24_-_23570846 0.67 ENSDART00000084954
ENSDART00000004013
ENSDART00000129028
phosphatidylinositol glycan anchor biosynthesis, class N
chr21_-_30247906 0.67 ENSDART00000066363
ENSDARG00000045127
chr5_-_57053687 0.66 ENSDART00000144237
grass carp reovirus (GCRV)-induced gene 2p
chr7_-_51474798 0.66 ENSDART00000175523
histone deacetylase 8
chr15_-_14102102 0.66 ENSDART00000139068
zgc:114130
chr21_+_15637516 0.66 ENSDART00000149371
isocitrate dehydrogenase 3 (NAD+) beta
chr25_+_30627892 0.66

chr10_-_25366450 0.65 ENSDART00000123820
transmembrane protein 135
chr12_-_19063761 0.65 ENSDART00000153343
zinc finger CCCH-type containing 7B
chr12_+_19837053 0.65 ENSDART00000015780
excision repair cross-complementation group 4
chr21_+_26954898 0.65 ENSDART00000114469
FK506 binding protein 2
chr22_-_26269585 0.65 ENSDART00000043774
SDE2 telomere maintenance homolog (S. pombe)
chr4_-_13932592 0.65 ENSDART00000067174
zinc finger CCHC-type and RNA binding motif 1
chr8_-_13231600 0.64 ENSDART00000014528
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1b
chr3_-_35735315 0.64 ENSDART00000102952
SUZ12 polycomb repressive complex 2a subunit
chr13_-_50940520 0.64

chr7_-_51474531 0.64 ENSDART00000083190
histone deacetylase 8
chr5_+_23582676 0.64 ENSDART00000139520
tumor protein p53
chr17_+_21797726 0.63 ENSDART00000079011
IKAROS family zinc finger 5
chr16_-_7703633 0.63 ENSDART00000148581
ENSDARG00000095852
chr7_-_25991514 0.63 ENSDART00000137769
adaptor-related protein complex 1, sigma 1 subunit
chr12_+_4651222 0.63 ENSDART00000128145
KAT8 regulatory NSL complex subunit 1a
chr5_-_68408107 0.63 ENSDART00000109761
ENSDART00000156681
ENSDART00000167680
ENSDARG00000076888
chr7_-_24604255 0.63 ENSDART00000173920
adenosine deaminase domain containing 2
chr14_+_30390987 0.63

chr13_-_36635434 0.63 ENSDART00000179302
mitogen-activated protein kinase kinase kinase kinase 5
chr17_-_49256667 0.63 ENSDART00000112806
origin recognition complex, subunit 3
chr7_+_22042296 0.63 ENSDART00000123457
transmembrane protein 102
chr8_-_21110183 0.62 ENSDART00000143192
carnitine palmitoyltransferase 2
chr13_-_49886891 0.62 ENSDART00000074230
protein kinase containing Z-DNA binding domains
chr23_-_29952057 0.62 ENSDART00000058407
solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr23_-_32173435 0.62 ENSDART00000044658
LETM1 domain containing 1
chr15_-_33342455 0.62

chr1_-_46423056 0.61 ENSDART00000053157
SET domain containing 4
chr1_+_39141680 0.61 ENSDART00000149984
interferon regulatory factor 2a
chr23_-_17503329 0.61 ENSDART00000132024
pancreatic progenitor cell differentiation and proliferation factor b
chr7_-_8465929 0.61 ENSDART00000172928
testis expressed 261
chr20_+_37592206 0.61 ENSDART00000153092
ENSDARG00000096774
chr7_+_21485734 0.60 ENSDART00000173641
lysine (K)-specific demethylase 6B, a
chr3_+_16692138 0.60 ENSDART00000023985
zgc:153952
chr2_+_44041230 0.60 ENSDART00000143885
guanylate binding protein 3
chr6_+_11162062 0.60 ENSDART00000151548
SUMO1/sentrin/SMT3 specific peptidase 2
chr20_+_32620786 0.60 ENSDART00000147319
sex comb on midleg-like 4 (Drosophila)
chr13_+_29795897 0.60 ENSDART00000131609
CUE domain containing 2
chr10_+_20435169 0.60 ENSDART00000160803
R3H domain and coiled-coil containing 1
chr17_-_31802796 0.60 ENSDART00000172519
abraxas 2b, BRISC complex subunit
chr7_+_5789700 0.59 ENSDART00000173025
si:dkey-23a13.9
chr19_-_26188747 0.59 ENSDART00000052393
par-6 family cell polarity regulator gamma b
chr21_-_7322856 0.59 ENSDART00000151543
ENSDART00000114982
coagulation factor II (thrombin) receptor-like 1, tandem duplicate 2
chr19_-_30834980 0.59 ENSDART00000043554
protein phosphatase 1, regulatory subunit 10
chr23_-_24616306 0.58 ENSDART00000088777
ATPase type 13A2
chr4_+_72009475 0.58 ENSDART00000172536
zinc finger protein 989
chr13_-_6195363 0.58 ENSDART00000148907
microcephalin 1
chr3_-_141976 0.58 ENSDART00000114289
ENSDARG00000075737

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0051977 maintenance of blood-brain barrier(GO:0035633) lysophospholipid transport(GO:0051977) lipid transport across blood brain barrier(GO:1990379)
0.7 2.8 GO:0072111 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.5 1.5 GO:0021755 glial cell migration(GO:0008347) eurydendroid cell differentiation(GO:0021755)
0.4 1.2 GO:0045813 positive regulation of Wnt signaling pathway, calcium modulating pathway(GO:0045813)
0.4 1.6 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.3 1.0 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.3 1.2 GO:0046078 dUMP biosynthetic process(GO:0006226) dUMP metabolic process(GO:0046078)
0.3 1.7 GO:0010526 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.3 1.0 GO:0046100 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine metabolic process(GO:0046098) guanine biosynthetic process(GO:0046099) hypoxanthine metabolic process(GO:0046100)
0.2 0.7 GO:0006683 galactosylceramide catabolic process(GO:0006683) galactolipid catabolic process(GO:0019376)
0.2 1.0 GO:0072574 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.2 1.6 GO:0070933 histone H4 deacetylation(GO:0070933)
0.2 0.9 GO:1903533 regulation of protein targeting(GO:1903533)
0.2 1.6 GO:0016578 histone deubiquitination(GO:0016578)
0.2 0.9 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.2 0.8 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.2 1.0 GO:0021588 cerebellum formation(GO:0021588)
0.2 0.6 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.2 0.8 GO:0042823 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.2 0.6 GO:0009098 leucine biosynthetic process(GO:0009098)
0.2 0.8 GO:1901052 sarcosine metabolic process(GO:1901052)
0.2 2.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.2 0.5 GO:0097704 response to oscillatory fluid shear stress(GO:0097702) cellular response to oscillatory fluid shear stress(GO:0097704)
0.2 1.1 GO:0006108 malate metabolic process(GO:0006108)
0.2 0.6 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.2 0.8 GO:0006741 NADP biosynthetic process(GO:0006741)
0.2 0.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 0.5 GO:0015911 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) regulation of organic acid transport(GO:0032890) positive regulation of organic acid transport(GO:0032892) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transport(GO:1903793) regulation of anion transmembrane transport(GO:1903959) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.2 0.9 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.7 GO:0060217 phosphatidylinositol acyl-chain remodeling(GO:0036149) hemangioblast cell differentiation(GO:0060217)
0.1 1.1 GO:0044206 pyrimidine-containing compound salvage(GO:0008655) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206) CTP salvage(GO:0044211)
0.1 0.6 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.8 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.4 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.4 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 0.6 GO:1901255 nucleotide-excision repair involved in interstrand cross-link repair(GO:1901255)
0.1 0.4 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.1 1.8 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 0.9 GO:0034087 establishment of mitotic sister chromatid cohesion(GO:0034087)
0.1 0.7 GO:0060296 regulation of cilium beat frequency(GO:0003356) regulation of translational termination(GO:0006449) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1 0.4 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.1 0.9 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.1 0.6 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.1 0.7 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.6 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.5 GO:1903449 male sex determination(GO:0030238) androst-4-ene-3,17-dione biosynthetic process(GO:1903449)
0.1 0.4 GO:0046931 pore complex assembly(GO:0046931) nuclear pore complex assembly(GO:0051292)
0.1 0.6 GO:0044034 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.1 0.4 GO:0032196 transposition(GO:0032196)
0.1 0.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.7 GO:0098869 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 1.6 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.1 0.5 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 0.4 GO:0043622 cortical microtubule organization(GO:0043622)
0.1 0.8 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.3 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.1 1.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.4 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.1 0.7 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.3 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.1 0.4 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.1 0.8 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.9 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.9 GO:0042026 protein refolding(GO:0042026)
0.1 1.4 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 2.8 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.1 0.6 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.3 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.1 0.3 GO:0006999 nuclear pore organization(GO:0006999)
0.1 0.6 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.5 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 1.9 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.6 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.5 GO:1904666 regulation of ubiquitin protein ligase activity(GO:1904666)
0.1 0.3 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.7 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 0.5 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.8 GO:0050779 RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.1 0.4 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.5 GO:0006265 DNA topological change(GO:0006265)
0.1 0.1 GO:0060876 semicircular canal formation(GO:0060876)
0.1 0.3 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
0.1 0.3 GO:0000012 single strand break repair(GO:0000012)
0.1 0.3 GO:0051657 maintenance of organelle location(GO:0051657)
0.1 1.0 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 0.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 0.6 GO:0016926 protein desumoylation(GO:0016926)
0.0 3.1 GO:0051028 mRNA transport(GO:0051028)
0.0 1.4 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 1.3 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.1 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.6 GO:0048669 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.5 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.2 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.0 0.2 GO:0071674 positive regulation of lamellipodium assembly(GO:0010592) regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759) skeletal muscle satellite cell proliferation(GO:0014841) regulation of skeletal muscle satellite cell proliferation(GO:0014842) negative regulation of skeletal muscle cell proliferation(GO:0014859) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.3 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.3 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 0.2 GO:0051031 tRNA transport(GO:0051031)
0.0 1.1 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 1.0 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 0.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.5 GO:0009409 response to cold(GO:0009409)
0.0 0.8 GO:0000959 mitochondrial RNA metabolic process(GO:0000959)
0.0 1.8 GO:0006414 translational elongation(GO:0006414)
0.0 0.4 GO:0060232 delamination(GO:0060232)
0.0 0.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.4 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.7 GO:0050906 detection of stimulus involved in sensory perception(GO:0050906)
0.0 0.3 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 1.0 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.8 GO:0006284 base-excision repair(GO:0006284)
0.0 1.0 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.2 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
0.0 0.7 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.6 GO:0048599 oocyte development(GO:0048599)
0.0 0.8 GO:0031103 axon regeneration(GO:0031103)
0.0 0.3 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.5 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 0.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.7 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 1.2 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.1 GO:0043116 negative regulation of vascular permeability(GO:0043116) negative regulation of calcium ion import(GO:0090281)
0.0 1.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.6 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 0.3 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.1 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.0 2.6 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 2.1 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.1 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.2 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.7 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.4 GO:0006298 mismatch repair(GO:0006298)
0.0 0.5 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.2 GO:0048796 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 0.3 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 0.3 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.5 GO:0006278 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.3 GO:0046660 female sex differentiation(GO:0046660)
0.0 0.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.1 GO:0003197 endocardial cushion development(GO:0003197)
0.0 0.3 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.5 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.4 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.2 GO:0045661 regulation of myoblast differentiation(GO:0045661)
0.0 0.7 GO:0007283 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.1 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 0.1 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.0 GO:0070528 protein kinase C signaling(GO:0070528)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.4 GO:0001878 response to yeast(GO:0001878)
0.0 0.3 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 0.3 GO:0001510 RNA methylation(GO:0001510)
0.0 0.3 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.2 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0097189 apoptotic body(GO:0097189)
0.3 1.0 GO:0061689 tricellular tight junction(GO:0061689)
0.2 0.6 GO:1990077 primosome complex(GO:1990077)
0.2 1.5 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 0.9 GO:0031415 NatA complex(GO:0031415)
0.2 0.5 GO:0032585 multivesicular body membrane(GO:0032585)
0.2 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 0.5 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.2 0.5 GO:0070209 ASTRA complex(GO:0070209)
0.1 1.5 GO:0000974 Prp19 complex(GO:0000974)
0.1 0.9 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.6 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.9 GO:0032021 NELF complex(GO:0032021)
0.1 0.4 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.1 0.6 GO:0000439 core TFIIH complex(GO:0000439)
0.1 0.6 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.3 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 0.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.5 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1 1.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 1.1 GO:0044545 NSL complex(GO:0044545)
0.1 1.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 0.4 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.1 0.2 GO:0032545 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.1 1.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 0.4 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.1 0.7 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 1.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 3.1 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.4 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.5 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.3 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.7 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.3 GO:0089701 U2AF(GO:0089701)
0.0 1.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.7 GO:0030686 90S preribosome(GO:0030686)
0.0 2.7 GO:0000786 nucleosome(GO:0000786)
0.0 0.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.2 GO:0098533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 3.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.4 GO:0005776 autophagosome(GO:0005776)
0.0 0.6 GO:0036452 ESCRT complex(GO:0036452)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.8 GO:0031514 motile cilium(GO:0031514)
0.0 0.7 GO:0005643 nuclear pore(GO:0005643)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.9 GO:0031201 SNARE complex(GO:0031201)
0.0 0.3 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.3 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.1 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.0 1.0 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 0.1 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0051978 lysophospholipid transporter activity(GO:0051978)
1.0 2.9 GO:0097020 COPII adaptor activity(GO:0097020)
0.8 2.5 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.5 1.6 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.4 1.6 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.4 1.1 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.3 1.0 GO:0052657 guanine phosphoribosyltransferase activity(GO:0052657)
0.3 1.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.3 0.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.3 0.8 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.3 1.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.3 0.8 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.2 0.7 GO:0004336 galactosylceramidase activity(GO:0004336)
0.2 1.9 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 0.7 GO:0052907 U6 snRNA 3'-end binding(GO:0030629) 23S rRNA (adenine(1618)-N(6))-methyltransferase activity(GO:0052907)
0.2 0.6 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 0.8 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326)
0.2 1.4 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.2 0.6 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 0.6 GO:0044548 S100 protein binding(GO:0044548)
0.2 0.6 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 0.9 GO:0009374 biotin binding(GO:0009374)
0.2 0.6 GO:0003896 DNA primase activity(GO:0003896)
0.2 0.9 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 0.7 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 0.9 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.2 2.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 0.5 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.2 0.7 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.2 1.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.2 0.8 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 0.6 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 1.1 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.7 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 1.6 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.6 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 2.3 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.1 0.3 GO:0004044 amidophosphoribosyltransferase activity(GO:0004044)
0.1 0.6 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.5 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1 0.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.5 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.4 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 0.3 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.1 0.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.6 GO:0070122 isopeptidase activity(GO:0070122)
0.1 0.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.6 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.3 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.1 0.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.6 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 2.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 2.2 GO:0005109 frizzled binding(GO:0005109)
0.1 1.0 GO:0019239 deaminase activity(GO:0019239)
0.1 0.6 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 0.5 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.3 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.2 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 0.6 GO:0042054 histone methyltransferase activity(GO:0042054)
0.1 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 1.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.9 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.4 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.8 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.2 GO:0003916 DNA topoisomerase activity(GO:0003916)
0.0 0.5 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 1.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.8 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 1.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.5 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.4 GO:2001069 glycogen binding(GO:2001069)
0.0 0.3 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.1 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.7 GO:0017069 snRNA binding(GO:0017069)
0.0 0.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.2 GO:0008026 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 1.3 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.4 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.9 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.0 0.5 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.8 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 2.5 GO:0019901 protein kinase binding(GO:0019901)
0.0 1.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.2 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0022839 ion gated channel activity(GO:0022839)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.2 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 2.0 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 2.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.3 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 1.0 GO:0019783 ubiquitin-like protein-specific protease activity(GO:0019783)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.7 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 0.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.8 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 3.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.9 PID FOXO PATHWAY FoxO family signaling
0.0 0.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.5 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.6 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.6 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.3 PID FGF PATHWAY FGF signaling pathway
0.0 0.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 2.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 1.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 1.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.5 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 0.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.0 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 1.2 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 0.6 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1 0.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 2.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.4 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.2 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.8 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle