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Results for pou4f2

Z-value: 0.56

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Transcription factors associated with pou4f2

Gene Symbol Gene ID Gene Info
pou4f2
ENSDARG00000069737 POU class 4 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou4f2dr10_dc_chr1_+_35704610_357046300.656.5e-03Click!

Activity profile of pou4f2 motif

Sorted Z-values of pou4f2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of pou4f2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr17_+_15425559 1.17 ENSDART00000026180
fabp7a
fatty acid binding protein 7, brain, a
chr5_-_30015572 0.98 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr16_+_46145286 0.76 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr24_-_21778717 0.76 ENSDART00000131944
tagln3b
transgelin 3b
chr8_+_15989815 0.76 ENSDART00000110171
elavl4
ELAV like neuron-specific RNA binding protein 4
chr6_+_27156169 0.70 ENSDART00000088364
kif1aa
kinesin family member 1Aa
chr7_+_32097831 0.64 ENSDART00000169588
LGR4
leucine rich repeat containing G protein-coupled receptor 4
chr1_+_46537108 0.63

chr22_-_13018196 0.63 ENSDART00000028787
ahr1b
aryl hydrocarbon receptor 1b
chr15_-_31687 0.61

chr16_-_12282596 0.59 ENSDART00000110567
clstn3
calsyntenin 3
chr23_+_22763861 0.56

chr23_+_22763789 0.55

chr13_+_35213326 0.53 ENSDART00000019323
jag1b
jagged 1b
chr25_+_30472954 0.49

chr7_+_73408688 0.49 ENSDART00000159745
PCP4L1
Purkinje cell protein 4 like 1
chr25_+_30473054 0.47

chr1_-_50215233 0.47 ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr3_-_28120668 0.45

chr16_+_51319421 0.44

chr5_+_17120453 0.42

chr3_-_30303173 0.40 ENSDART00000150958
lrrc4ba
leucine rich repeat containing 4Ba
chr17_-_12772433 0.39 ENSDART00000044126
ENSDARG00000020655
ENSDARG00000020655
chr4_-_1346961 0.39 ENSDART00000164623
ptn
pleiotrophin
chr11_-_42626842 0.38 ENSDART00000052912
pcdh20
protocadherin 20
chr5_-_71643185 0.37 ENSDART00000029014
pax8
paired box 8
chr5_-_62821458 0.37 ENSDART00000022348
prdm12b
PR domain containing 12b
chr15_-_46670611 0.37

chr9_-_32942783 0.36 ENSDART00000060006
olig2
oligodendrocyte lineage transcription factor 2
chr15_-_24987099 0.34

chr11_+_38013238 0.34 ENSDART00000171496
CDK18
cyclin dependent kinase 18
chr3_+_43010408 0.33 ENSDART00000169061
CU138533.1
ENSDARG00000099842
chr6_+_3873114 0.32 ENSDART00000159952
sema5bb
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Bb
chr6_-_43094573 0.32 ENSDART00000084389
lrrn1
leucine rich repeat neuronal 1
chr25_+_6059393 0.32 ENSDART00000154658
oaz2a
ornithine decarboxylase antizyme 2a
chr8_-_27839244 0.32 ENSDART00000136562
cttnbp2nlb
CTTNBP2 N-terminal like b
chr14_+_46896395 0.31 ENSDART00000114790
flrt1b
fibronectin leucine rich transmembrane protein 1b
chr6_+_39186673 0.31 ENSDART00000156187
tac3b
tachykinin 3b
chr8_-_15091823 0.31 ENSDART00000142358
bcar3
breast cancer anti-estrogen resistance 3
chr20_-_38714872 0.30 ENSDART00000050474
slc30a2
solute carrier family 30 (zinc transporter), member 2
chr12_-_10372055 0.30 ENSDART00000052001
eef2k
eukaryotic elongation factor 2 kinase
chr3_-_28120760 0.30

chr3_+_47735048 0.29 ENSDART00000083024
gpr146
G protein-coupled receptor 146
chr21_+_37668334 0.29 ENSDART00000143621
nsd1b
nuclear receptor binding SET domain protein 1b
chr1_+_53127046 0.29

chr1_-_18581114 0.28 ENSDART00000178278
BX546494.1
ENSDARG00000107606
KN150670v1_-_72156 0.28

chr23_+_22763739 0.28

chr2_-_44329092 0.28

chr6_+_54179493 0.27 ENSDART00000056830
pacsin1b
protein kinase C and casein kinase substrate in neurons 1b
chr20_+_54595334 0.27

chr20_-_18836593 0.26 ENSDART00000142837
enpp5
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr1_-_37475807 0.26 ENSDART00000020409
hand2
heart and neural crest derivatives expressed 2
chr1_+_13779755 0.25

chr9_-_39190534 0.25

chr7_+_73408746 0.25 ENSDART00000159745
PCP4L1
Purkinje cell protein 4 like 1
chr21_+_36938230 0.23 ENSDART00000027459
grk6
G protein-coupled receptor kinase 6
chr17_+_26946957 0.23 ENSDART00000114215
grhl3
grainyhead-like transcription factor 3
chr23_+_25378921 0.23 ENSDART00000143291
RPL41
ribosomal protein L41
chr3_-_58739476 0.22 ENSDART00000161248
si:ch73-281f12.4
si:ch73-281f12.4
chr10_+_39291358 0.22 ENSDART00000159501
stt3a
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr11_-_44724371 0.22 ENSDART00000166501
cant1b
calcium activated nucleotidase 1b
chr2_+_29265967 0.21 ENSDART00000099157
cdh18a
cadherin 18, type 2a
chr18_+_1353857 0.19 ENSDART00000165301
rab27a
RAB27A, member RAS oncogene family
chr12_+_24833569 0.18 ENSDART00000014868
calm3a
calmodulin 3a (phosphorylase kinase, delta)
chr17_-_37447917 0.17 ENSDART00000075975
crip1
cysteine-rich protein 1
chr6_-_8009055 0.17 ENSDART00000151358
rgl3a
ral guanine nucleotide dissociation stimulator-like 3a
chr8_-_4270732 0.16 ENSDART00000134378
cux2b
cut-like homeobox 2b
chr16_+_11295005 0.15

chr24_+_26287471 0.15 ENSDART00000105784
ENSDART00000122554
cldn11b
claudin 11b
chr8_+_6533379 0.15 ENSDART00000138135
vsig8b
V-set and immunoglobulin domain containing 8b
chr6_-_43094926 0.13 ENSDART00000084389
lrrn1
leucine rich repeat neuronal 1
chr18_+_6664159 0.13

chr2_-_26160882 0.13 ENSDART00000133163
CR392026.2
ENSDARG00000094803
chr19_+_1743359 0.13 ENSDART00000166744
dennd3a
DENN/MADD domain containing 3a
chr24_-_41403824 0.13 ENSDART00000063504
ENSDART00000169374
xylb
xylulokinase homolog (H. influenzae)
chr18_-_40518772 0.12 ENSDART00000021372
chrna5
cholinergic receptor, nicotinic, alpha 5
chr13_-_46423391 0.12

chr2_-_40170303 0.11 ENSDART00000165602
epha4a
eph receptor A4a
chr3_-_58739399 0.11 ENSDART00000161248
si:ch73-281f12.4
si:ch73-281f12.4
chr13_-_42274486 0.10 ENSDART00000043069
march5
membrane-associated ring finger (C3HC4) 5
chr9_+_38278401 0.10 ENSDART00000123749
cacnb4a
calcium channel, voltage-dependent, beta 4a subunit
chr4_-_2707563 0.09 ENSDART00000021953
ENSDART00000150344
cog5
component of oligomeric golgi complex 5
chr15_-_56306 0.09 ENSDART00000168340
CABZ01080370.1
POU class 2 homeobox 1a
chr15_+_43192811 0.09

chr11_+_44240444 0.09 ENSDART00000172998
ero1b
endoplasmic reticulum oxidoreductase beta
chr17_-_12812747 0.09 ENSDART00000022874
ENSDART00000046025
psma6a
proteasome subunit alpha 6a
chr7_-_52848084 0.09 ENSDART00000172179
ENSDART00000167882
cdh1
cadherin 1, type 1, E-cadherin (epithelial)
chr8_+_8889274 0.07 ENSDART00000142075
pim2
Pim-2 proto-oncogene, serine/threonine kinase
chr23_-_17524325 0.06 ENSDART00000104680
tpd52l2b
tumor protein D52-like 2b
chr2_+_36957471 0.06 ENSDART00000143915
gadd45bb
growth arrest and DNA-damage-inducible, beta b
chr13_+_36496475 0.06 ENSDART00000133198
si:ch211-67f24.7
si:ch211-67f24.7
chr7_+_17527276 0.06

chr7_-_7530898 0.06 ENSDART00000113131
intu
inturned planar cell polarity protein
chr22_-_342682 0.05 ENSDART00000067633
necap2
NECAP endocytosis associated 2
chr7_-_17527827 0.05 ENSDART00000128504
si:dkey-106g10.7
si:dkey-106g10.7
chr19_-_5186692 0.05 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr17_-_20182801 0.03 ENSDART00000133650
ecd
ecdysoneless homolog (Drosophila)
chr4_+_9835529 0.03 ENSDART00000004879
hsp90b1
heat shock protein 90, beta (grp94), member 1
chr4_+_13430131 0.03 ENSDART00000137200
si:dkey-39a18.1
si:dkey-39a18.1
chr20_-_18836698 0.02 ENSDART00000142837
enpp5
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr2_-_10020770 0.02 ENSDART00000046587
ap2m1a
adaptor-related protein complex 2, mu 1 subunit, a
chr9_-_50304120 0.02 ENSDART00000161648
ENSDART00000168514
scn1a
sodium channel, voltage-gated, type I, alpha
chr18_-_15582896 0.01 ENSDART00000172690
ENSDART00000159915
ppfibp1b
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr17_-_37447869 0.01 ENSDART00000148160
crip1
cysteine-rich protein 1
chr8_+_17132156 0.01 ENSDART00000134665
cenph
centromere protein H

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.1 0.4 GO:0021742 abducens nucleus development(GO:0021742)
0.1 0.3 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 0.6 GO:0051965 regulation of synapse assembly(GO:0051963) positive regulation of synapse assembly(GO:0051965)
0.1 0.3 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.1 0.3 GO:0045777 positive regulation of blood pressure(GO:0045777)
0.1 0.7 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.5 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.1 0.2 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.0 0.1 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.4 GO:0034672 anterior/posterior pattern specification involved in pronephros development(GO:0034672) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.0 0.3 GO:0002093 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.3 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.1 GO:0035094 response to nicotine(GO:0035094)
0.0 0.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.6 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.2 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.3 GO:0006595 polyamine metabolic process(GO:0006595)
0.0 0.1 GO:0003379 establishment of cell polarity involved in gastrulation cell migration(GO:0003379)
0.0 0.1 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.0 0.0 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.7 GO:0043204 perikaryon(GO:0043204)
0.0 0.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.7 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.2 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.3 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.3 GO:0051020 GTPase binding(GO:0051020)
0.0 0.0 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.0 0.2 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing