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Results for pou6f1

Z-value: 0.58

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Transcription factors associated with pou6f1

Gene Symbol Gene ID Gene Info
pou6f1
ENSDARG00000011570 POU class 6 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou6f1dr10_dc_chr23_-_33783345_33783373-0.835.7e-05Click!

Activity profile of pou6f1 motif

Sorted Z-values of pou6f1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of pou6f1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_+_56970554 1.88 ENSDART00000162930
bahcc1a
BAH domain and coiled-coil containing 1a
chr9_-_14533551 1.46 ENSDART00000056103
nrp2b
neuropilin 2b
chr19_-_31815128 1.40 ENSDART00000137292
tmem106bb
transmembrane protein 106Bb
chr23_+_35819625 1.35 ENSDART00000049551
rarga
retinoic acid receptor gamma a
chr4_-_76620869 1.05

KN150207v1_-_1208 1.01 ENSDART00000171112
CABZ01112575.1
ENSDARG00000099354
chr21_-_22510751 1.01 ENSDART00000169870
myo5b
myosin VB
chr22_-_13325409 0.95 ENSDART00000154095
si:ch211-227m13.1
si:ch211-227m13.1
chr5_-_13872815 0.93 ENSDART00000164698
CT009570.1
ENSDARG00000104490
chr22_-_336857 0.90

chr13_+_21989327 0.83 ENSDART00000173206
camk2g2
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 2
chr1_+_13779755 0.80

chr22_+_25652275 0.78 ENSDART00000087769
si:ch211-250e5.2
si:ch211-250e5.2
chr13_+_371940 0.76 ENSDART00000013007
degs1
delta(4)-desaturase, sphingolipid 1
chr15_-_17933972 0.76 ENSDART00000155066
atf5b
activating transcription factor 5b
chr12_+_20230575 0.74 ENSDART00000066383
hbae5
hemoglobin, alpha embryonic 5
chr7_-_46510632 0.73

chr22_+_16509286 0.73 ENSDART00000083063
tal1
T-cell acute lymphocytic leukemia 1
chr9_-_30437160 0.71 ENSDART00000147241
BX936337.1
ENSDARG00000092870
chr1_+_51706536 0.70

chr19_-_35513216 0.66

chr7_+_25794014 0.64 ENSDART00000174010
ENSDART00000173815
CT027989.1
ENSDARG00000105638
chr25_+_36878565 0.61 ENSDART00000157596
ric3b
RIC3 acetylcholine receptor chaperone b
chr22_-_337198 0.59

chr19_-_22182031 0.57 ENSDART00000104279
znf516
zinc finger protein 516
chr9_-_785511 0.57 ENSDART00000012506
en1a
engrailed homeobox 1a
chr2_-_44402486 0.55 ENSDART00000011188
ENSDART00000093298
atp1a2a
ATPase, Na+/K+ transporting, alpha 2a polypeptide
chr3_+_21059221 0.55 ENSDART00000078807
zgc:123295
zgc:123295
chr8_+_14120313 0.54 ENSDART00000080832
si:dkey-6n6.2
si:dkey-6n6.2
chr9_-_41982635 0.54 ENSDART00000144573
obsl1b
obscurin-like 1b
chr7_-_72500748 0.53 ENSDART00000160523
CU929444.1
ENSDARG00000099109
chr17_+_12544451 0.51 ENSDART00000064509
ENSDART00000136830
stmn4l
stathmin-like 4, like
chr19_+_42899678 0.51 ENSDART00000076915
si:dkey-166k12.1
si:dkey-166k12.1
chr10_+_2688361 0.50 ENSDART00000130793
grk5
G protein-coupled receptor kinase 5
chr15_-_33782909 0.49 ENSDART00000167705
stard13b
StAR-related lipid transfer (START) domain containing 13b
chr24_-_23155932 0.49

chr11_-_6442836 0.47 ENSDART00000004483
zgc:162969
zgc:162969
chr16_-_11908084 0.47 ENSDART00000135408
cnfn
cornifelin
chr4_+_12616987 0.46 ENSDART00000003583
lmo3
LIM domain only 3
chr4_+_12617165 0.46 ENSDART00000003583
lmo3
LIM domain only 3
chr13_+_18401965 0.46 ENSDART00000136024
ftr14l
finTRIM family, member 14-like
chr6_+_60060297 0.45 ENSDART00000178621
pck1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr9_-_22528568 0.45 ENSDART00000134805
crygm2d1
crystallin, gamma M2d1
chr22_-_13325475 0.45 ENSDART00000154095
si:ch211-227m13.1
si:ch211-227m13.1
chr22_-_336942 0.43

chr11_-_7310284 0.42 ENSDART00000091664
apc2
adenomatosis polyposis coli 2
chr18_-_50527399 0.42 ENSDART00000033591
cd276
CD276 molecule
chr12_+_18559530 0.41 ENSDART00000152948
rgs9b
regulator of G protein signaling 9b
chr18_+_34205362 0.41 ENSDART00000130831
gmps
guanine monophosphate synthase
chr7_-_9557990 0.40 ENSDART00000055593
aldh1a3
aldehyde dehydrogenase 1 family, member A3
chr1_+_51706568 0.40

chr4_-_1564624 0.38 ENSDART00000168633
BICD1 (1 of many)
BICD cargo adaptor 1
chr9_-_785569 0.38 ENSDART00000012506
en1a
engrailed homeobox 1a
chr8_+_14120357 0.38 ENSDART00000080832
si:dkey-6n6.2
si:dkey-6n6.2
chr17_-_43725003 0.36

chr7_+_25793777 0.35 ENSDART00000174010
ENSDART00000173815
CT027989.1
ENSDARG00000105638
chr13_+_43266551 0.35 ENSDART00000084321
dact2
dishevelled-binding antagonist of beta-catenin 2
chr13_-_11553609 0.35

chr5_-_38022706 0.34

chr2_+_29265967 0.32 ENSDART00000099157
cdh18a
cadherin 18, type 2a
chr5_-_70915664 0.31

chr7_-_14937467 0.29 ENSDART00000031049
ENSDARG00000023868
ENSDARG00000023868
chr8_+_37136126 0.28 ENSDART00000098636
csf1b
colony stimulating factor 1b (macrophage)
chr2_-_44402452 0.27 ENSDART00000011188
ENSDART00000093298
atp1a2a
ATPase, Na+/K+ transporting, alpha 2a polypeptide
chr14_+_45619218 0.27 ENSDART00000158723
sncb
synuclein, beta
chr19_+_21781738 0.26

chr17_-_49355712 0.26 ENSDART00000004424
znf292a
zinc finger protein 292a
chr9_-_785400 0.26 ENSDART00000012506
en1a
engrailed homeobox 1a
chr22_+_11490729 0.25 ENSDART00000063147
sgsh
N-sulfoglucosamine sulfohydrolase (sulfamidase)
chr10_-_24422496 0.25 ENSDART00000141332
ENSDART00000100772
slc43a2b
solute carrier family 43 (amino acid system L transporter), member 2b
chr13_+_21989216 0.25 ENSDART00000165842
camk2g2
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 2
chr2_-_50638153 0.25 ENSDART00000108900
cntnap2b
contactin associated protein-like 2b
chr5_-_13872772 0.24 ENSDART00000164698
CT009570.1
ENSDARG00000104490
chr4_-_13394059 0.23 ENSDART00000175909
ENSDART00000174861
BX511038.1
ENSDARG00000108089
chr18_+_1353738 0.23 ENSDART00000165301
rab27a
RAB27A, member RAS oncogene family
chr4_-_74789596 0.23 ENSDART00000174356
ENSDART00000174313
si:ch73-158p21.3
si:ch73-158p21.3
chr3_-_8608620 0.22

chr1_-_24493345 0.22 ENSDART00000177225
tmem154
transmembrane protein 154
chr17_+_1986151 0.21 ENSDART00000103775
pak6a
p21 protein (Cdc42/Rac)-activated kinase 6a
chr23_-_36198253 0.20

chr2_+_6331176 0.20 ENSDART00000058258
gng5
guanine nucleotide binding protein (G protein), gamma 5
chr2_-_21323717 0.19 ENSDART00000113384
lyrm4
LYR motif containing 4
chr10_-_45212226 0.19 ENSDART00000170413
mrps24
mitochondrial ribosomal protein S24
chr14_-_28260272 0.18 ENSDART00000172547
insb
preproinsulin b
chr18_-_15582896 0.18 ENSDART00000172690
ENSDART00000159915
ppfibp1b
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr23_+_46015863 0.17 ENSDART00000012234
syap1
synapse associated protein 1
chr19_-_11161797 0.17

chr4_+_17088146 0.16

chr25_+_6059393 0.16 ENSDART00000154658
oaz2a
ornithine decarboxylase antizyme 2a
chr15_-_5732737 0.15 ENSDART00000109599
urb1
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
chr16_-_5254337 0.15 ENSDART00000134981
dctn3
dynactin 3 (p22)
chr6_-_43782889 0.13

chr12_-_22387786 0.11 ENSDART00000109707
neurl4
neuralized E3 ubiquitin protein ligase 4
chr5_+_21593388 0.11 ENSDART00000090375
zc3h12b
zinc finger CCCH-type containing 12B
chr8_+_30446599 0.11 ENSDART00000085894
pgm5
phosphoglucomutase 5
chr22_+_34735496 0.09 ENSDART00000155906
hoga1
4-hydroxy-2-oxoglutarate aldolase 1
chr19_+_46631965 0.08 ENSDART00000158703
vps28
vacuolar protein sorting 28 (yeast)
chr17_-_49355906 0.08 ENSDART00000162563
znf292a
zinc finger protein 292a
chr6_-_9440411 0.08 ENSDART00000169915
nop58
NOP58 ribonucleoprotein homolog (yeast)
chr3_+_21059313 0.06 ENSDART00000141410
zgc:123295
zgc:123295
chr25_+_7287952 0.05 ENSDART00000170569
syt12
synaptotagmin XII
chr14_+_47016666 0.05 ENSDART00000145241
slu7
SLU7 homolog, splicing factor
chr23_-_17524325 0.05 ENSDART00000104680
tpd52l2b
tumor protein D52-like 2b
chr18_+_1353857 0.04 ENSDART00000165301
rab27a
RAB27A, member RAS oncogene family
chr9_+_41910191 0.04

chr12_+_48176075 0.03

chr5_-_39136238 0.03 ENSDART00000127123
rasgef1ba
RasGEF domain family, member 1Ba
chr21_-_20295921 0.02 ENSDART00000166049
slc26a1
solute carrier family 26 (anion exchanger), member 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0003242 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.3 0.8 GO:0010084 specification of organ axis polarity(GO:0010084)
0.2 0.7 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.2 1.5 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.1 1.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.5 GO:0046327 propionate metabolic process(GO:0019541) propionate catabolic process(GO:0019543) glycerol biosynthetic process from pyruvate(GO:0046327) cellular response to dexamethasone stimulus(GO:0071549)
0.1 1.4 GO:0032418 lysosome localization(GO:0032418)
0.1 0.3 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.7 GO:0015671 oxygen transport(GO:0015671)
0.0 0.4 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.4 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 0.3 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 1.4 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.4 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.8 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.3 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 1.1 GO:0001666 response to hypoxia(GO:0001666)
0.0 0.2 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0005833 hemoglobin complex(GO:0005833) haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 1.4 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.1 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.0 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.3 GO:0043679 axon terminus(GO:0043679)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.5 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 0.7 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.3 GO:1903136 cuprous ion binding(GO:1903136)
0.1 0.5 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.6 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.4 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.4 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 1.4 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation