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Results for pou6f2

Z-value: 0.93

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Transcription factors associated with pou6f2

Gene Symbol Gene ID Gene Info
pou6f2
ENSDARG00000086362 POU class 6 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou6f2dr10_dc_chr24_+_9898743_9898830-0.902.8e-06Click!

Activity profile of pou6f2 motif

Sorted Z-values of pou6f2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of pou6f2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_+_56970554 3.16 ENSDART00000162930
bahcc1a
BAH domain and coiled-coil containing 1a
chr8_-_26623251 3.13 ENSDART00000159264
sema3b
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr23_+_35819625 2.96 ENSDART00000049551
rarga
retinoic acid receptor gamma a
chr13_+_35213326 2.69 ENSDART00000019323
jag1b
jagged 1b
chr18_+_5899355 2.62

chr12_-_17576409 2.30 ENSDART00000147282
pvalb9
parvalbumin 9
chr20_-_22576513 2.25 ENSDART00000103510
pdgfra
platelet-derived growth factor receptor, alpha polypeptide
chr19_+_31046291 2.11 ENSDART00000052124
fam49al
family with sequence similarity 49, member A-like
chr6_+_3873114 2.05 ENSDART00000159952
sema5bb
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Bb
chr15_-_31687 1.97

chr3_-_6078015 1.97 ENSDART00000165715
BX284638.1
ENSDARG00000098850
chr24_-_21778717 1.94 ENSDART00000131944
tagln3b
transgelin 3b
chr22_-_13325409 1.90 ENSDART00000154095
si:ch211-227m13.1
si:ch211-227m13.1
chr12_-_17576531 1.88 ENSDART00000105974
pvalb9
parvalbumin 9
chr3_-_60929921 1.81 ENSDART00000055064
pvalb8
parvalbumin 8
chr9_-_14533551 1.72 ENSDART00000056103
nrp2b
neuropilin 2b
chr3_-_42649955 1.68 ENSDART00000171213
uncx
UNC homeobox
chr3_-_32202533 1.68 ENSDART00000155757
si:dkey-16p21.8
si:dkey-16p21.8
chr6_-_43094573 1.60 ENSDART00000084389
lrrn1
leucine rich repeat neuronal 1
chr15_-_4537178 1.55 ENSDART00000155619
ENSDART00000128602
tfdp2
transcription factor Dp-2
chr19_-_31815128 1.55 ENSDART00000137292
tmem106bb
transmembrane protein 106Bb
chr21_-_39132283 1.54 ENSDART00000065143
unc119b
unc-119 homolog b (C. elegans)
chr7_-_31488479 1.53 ENSDART00000113467
igdcc4
immunoglobulin superfamily, DCC subclass, member 4
chr2_+_55888093 1.50 ENSDART00000146160
loxl5b
lysyl oxidase-like 5b
chr17_+_25503946 1.49

chr13_+_24531753 1.48 ENSDART00000014176
msx3
muscle segment homeobox 3
chr9_-_30437160 1.45 ENSDART00000147241
BX936337.1
ENSDARG00000092870
chr4_-_17640519 1.44 ENSDART00000108814
nrip2
nuclear receptor interacting protein 2
chr12_-_26314881 1.42 ENSDART00000178687
myoz1b
myozenin 1b
chr2_-_44402486 1.39 ENSDART00000011188
ENSDART00000093298
atp1a2a
ATPase, Na+/K+ transporting, alpha 2a polypeptide
chr12_+_20230575 1.37 ENSDART00000066383
hbae5
hemoglobin, alpha embryonic 5
chr11_-_27455242 1.37 ENSDART00000045942
phf2
PHD finger protein 2
chr4_-_15442828 1.34 ENSDART00000157414
plxna4
plexin A4
chr24_+_24308055 1.33

chr1_+_13779755 1.32

chr6_+_27156169 1.25 ENSDART00000088364
kif1aa
kinesin family member 1Aa
chr3_-_42649907 1.24 ENSDART00000171213
uncx
UNC homeobox
chr9_-_32942783 1.24 ENSDART00000060006
olig2
oligodendrocyte lineage transcription factor 2
chr25_-_14472107 1.23

chr15_-_17933972 1.23 ENSDART00000155066
atf5b
activating transcription factor 5b
chr2_-_35584440 1.21 ENSDART00000125298
tnw
tenascin W
chr24_+_9603813 1.18 ENSDART00000129656
tmem108
transmembrane protein 108
chr11_-_37158131 1.17 ENSDART00000160911
erc2
ELKS/RAB6-interacting/CAST family member 2
chr16_+_46145286 1.17 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr3_-_56474209 1.15 ENSDART00000156398
si:ch211-189a21.1
si:ch211-189a21.1
chr11_+_19894772 1.15 ENSDART00000103997
fezf2
FEZ family zinc finger 2
chr23_+_31181140 1.14 ENSDART00000103448
tbx18
T-box 18
chr13_-_22515619 1.14 ENSDART00000136808
ENSDART00000131262
mmrn2a
multimerin 2a
chr17_-_48623315 1.13 ENSDART00000030934
kcnk5a
potassium channel, subfamily K, member 5a
chr7_-_46510632 1.12

chr3_-_60930025 1.10 ENSDART00000055064
pvalb8
parvalbumin 8
chr5_-_13872815 1.10 ENSDART00000164698
CT009570.1
ENSDARG00000104490
chr19_+_48499602 1.09

chr23_-_29138952 1.09 ENSDART00000002812
casz1
castor zinc finger 1
chr20_+_26408687 1.07

chr6_+_16279737 1.05 ENSDART00000040035
ccdc80l1
coiled-coil domain containing 80 like 1
chr19_-_22182031 1.03 ENSDART00000104279
znf516
zinc finger protein 516
chr11_-_27455348 1.02 ENSDART00000045942
phf2
PHD finger protein 2
chr1_-_54593214 1.02 ENSDART00000152807
si:ch211-286b5.5
si:ch211-286b5.5
chr22_-_13325475 1.02 ENSDART00000154095
si:ch211-227m13.1
si:ch211-227m13.1
chr8_-_27839244 0.99 ENSDART00000136562
cttnbp2nlb
CTTNBP2 N-terminal like b
chr23_-_24240728 0.99 ENSDART00000113598
arhgef19
Rho guanine nucleotide exchange factor (GEF) 19
chr14_-_9407573 0.98 ENSDART00000166739
NRK
si:zfos-2326c3.2
chr1_+_25005968 0.96 ENSDART00000054228
lrata
lecithin retinol acyltransferase a (phosphatidylcholine-retinol O-acyltransferase)
chr6_-_43094926 0.93 ENSDART00000084389
lrrn1
leucine rich repeat neuronal 1
chr13_-_31304614 0.92

chr5_+_26925238 0.91 ENSDART00000051491
sfrp1a
secreted frizzled-related protein 1a
chr21_-_24552672 0.91

chr20_-_48677794 0.90 ENSDART00000124040
ENSDART00000148437
insm1a
insulinoma-associated 1a
chr13_+_16148867 0.90 ENSDART00000142408
anxa11a
annexin A11a
chr4_+_12616987 0.90 ENSDART00000003583
lmo3
LIM domain only 3
chr20_+_29307142 0.90 ENSDART00000153016
katnbl1
katanin p80 subunit B-like 1
chr20_+_29307039 0.88 ENSDART00000152949
katnbl1
katanin p80 subunit B-like 1
chr20_-_3970778 0.88 ENSDART00000178724
ENSDART00000178565
TRIM67
tripartite motif containing 67
chr22_-_13018196 0.82 ENSDART00000028787
ahr1b
aryl hydrocarbon receptor 1b
chr11_-_42934175 0.81 ENSDART00000172929
sptbn1
spectrin, beta, non-erythrocytic 1
chr7_+_25794014 0.81 ENSDART00000174010
ENSDART00000173815
CT027989.1
ENSDARG00000105638
chr11_-_42933969 0.80 ENSDART00000172929
sptbn1
spectrin, beta, non-erythrocytic 1
chr15_-_46670611 0.80

chr9_-_41608298 0.80

chr17_-_47893203 0.80

chr13_-_44492897 0.79

chr3_-_28120668 0.77

chr13_+_42280697 0.77 ENSDART00000084354
cpeb3
cytoplasmic polyadenylation element binding protein 3
chr2_-_44402452 0.77 ENSDART00000011188
ENSDART00000093298
atp1a2a
ATPase, Na+/K+ transporting, alpha 2a polypeptide
chr22_+_25795022 0.76 ENSDART00000161120
vasna
vasorin a
chr4_+_12617165 0.75 ENSDART00000003583
lmo3
LIM domain only 3
chr2_-_50638153 0.75 ENSDART00000108900
cntnap2b
contactin associated protein-like 2b
chr23_+_28804842 0.74 ENSDART00000047378
sst3
somatostatin 3
chr9_-_43736549 0.73 ENSDART00000140526
znf385b
zinc finger protein 385B
chr3_+_17387551 0.73 ENSDART00000104549
hcrt
hypocretin (orexin) neuropeptide precursor
chr11_+_43924640 0.70 ENSDART00000179206
gnb4b
guanine nucleotide binding protein (G protein), beta polypeptide 4b
chr3_+_12132746 0.70

chr12_+_27444832 0.69 ENSDART00000133719
etv4
ets variant 4
chr11_+_19894390 0.67 ENSDART00000103997
fezf2
FEZ family zinc finger 2
chr22_-_12905648 0.65 ENSDART00000157820
mfsd6a
major facilitator superfamily domain containing 6a
chr11_-_42626842 0.64 ENSDART00000052912
pcdh20
protocadherin 20
chr4_+_11385828 0.64

chr3_+_23607148 0.63 ENSDART00000143981
hoxb3a
homeobox B3a
chr7_-_50359643 0.61 ENSDART00000174031
crtc3
CREB regulated transcription coactivator 3
chr18_+_37034218 0.60

chr3_-_30303173 0.59 ENSDART00000150958
lrrc4ba
leucine rich repeat containing 4Ba
chr13_+_18401965 0.58 ENSDART00000136024
ftr14l
finTRIM family, member 14-like
chr2_+_29265967 0.58 ENSDART00000099157
cdh18a
cadherin 18, type 2a
chr6_+_11594333 0.57 ENSDART00000109552
baz2ba
bromodomain adjacent to zinc finger domain, 2Ba
chr7_-_50359583 0.57 ENSDART00000174031
crtc3
CREB regulated transcription coactivator 3
chr9_-_39190534 0.56

chr6_+_44891187 0.56

chr6_+_16341787 0.54 ENSDART00000114667
zgc:161969
zgc:161969
chr9_-_41982635 0.54 ENSDART00000144573
obsl1b
obscurin-like 1b
chr25_+_6059393 0.53 ENSDART00000154658
oaz2a
ornithine decarboxylase antizyme 2a
chr6_+_44891278 0.51

chr24_-_23155932 0.51

chr8_+_6533379 0.50 ENSDART00000138135
vsig8b
V-set and immunoglobulin domain containing 8b
chr12_-_17576472 0.50 ENSDART00000147282
pvalb9
parvalbumin 9
chr18_-_43890514 0.49 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr6_-_40724581 0.47 ENSDART00000035101
kbtbd12
kelch repeat and BTB (POZ) domain containing 12
chr25_-_21618526 0.46 ENSDART00000152011
DOCK4 (1 of many)
dedicator of cytokinesis 4
chr18_+_1353738 0.46 ENSDART00000165301
rab27a
RAB27A, member RAS oncogene family
chr7_+_25793777 0.45 ENSDART00000174010
ENSDART00000173815
CT027989.1
ENSDARG00000105638
chr8_+_51061523 0.44 ENSDART00000166249
DISP3
dispatched RND transporter family member 3
chr23_-_24240798 0.43 ENSDART00000135173
CR925709.1
ENSDARG00000092130
KN149874v1_-_3544 0.42 ENSDART00000165981
CABZ01046348.1
ENSDARG00000099481
chr8_+_30446599 0.42 ENSDART00000085894
pgm5
phosphoglucomutase 5
chr23_+_17220363 0.41 ENSDART00000143420
BX927275.2
ENSDARG00000095017
chr11_+_19894420 0.41 ENSDART00000103997
fezf2
FEZ family zinc finger 2
chr11_-_6442836 0.40 ENSDART00000004483
zgc:162969
zgc:162969
chr14_-_6901415 0.40 ENSDART00000167994
ENSDART00000166532
stox2b
storkhead box 2b
chr16_+_31890795 0.39 ENSDART00000159821
atn1
atrophin 1
chr7_+_30874387 0.39 ENSDART00000075407
ENSDART00000169462
fam189a1
family with sequence similarity 189, member A1
chr9_+_33049445 0.37 ENSDART00000168992
si:dkey-145p14.5
si:dkey-145p14.5
chr3_-_8608620 0.37

chr23_-_29138719 0.37 ENSDART00000002812
casz1
castor zinc finger 1
chr19_+_8693914 0.36 ENSDART00000144925
snx27a
sorting nexin family member 27a
chr4_+_12613575 0.35 ENSDART00000133767
lmo3
LIM domain only 3
chr9_+_33049549 0.35 ENSDART00000121751
si:dkey-145p14.5
si:dkey-145p14.5
chr10_-_24422496 0.33 ENSDART00000141332
ENSDART00000100772
slc43a2b
solute carrier family 43 (amino acid system L transporter), member 2b
chr17_-_49355712 0.31 ENSDART00000004424
znf292a
zinc finger protein 292a
chr13_-_51409167 0.30 ENSDART00000174550
CABZ01090417.1
ENSDARG00000108080
chr5_-_71277652 0.29

chr3_-_33773025 0.27

chr8_+_8889274 0.27 ENSDART00000142075
pim2
Pim-2 proto-oncogene, serine/threonine kinase
chr13_+_24453943 0.26 ENSDART00000057599
fuom
fucose mutarotase
chr22_-_2942708 0.26 ENSDART00000040701
ing5a
inhibitor of growth family, member 5a
chr16_-_12282596 0.24 ENSDART00000110567
clstn3
calsyntenin 3
chr2_+_7127561 0.24 ENSDART00000050597
xpr1b
xenotropic and polytropic retrovirus receptor 1b
chr6_-_29094887 0.23

chr2_+_29729161 0.23 ENSDART00000141666
AL845362.1
ENSDARG00000093205
chr20_-_9448803 0.23 ENSDART00000133000
ENSDARG00000033201
ENSDARG00000033201
chr7_-_17527827 0.22 ENSDART00000128504
si:dkey-106g10.7
si:dkey-106g10.7
chr17_-_29885237 0.21 ENSDART00000009104
esrrga
estrogen-related receptor gamma a
chr13_+_25319230 0.20 ENSDART00000101328
atoh7
atonal bHLH transcription factor 7
chr11_+_19894502 0.20 ENSDART00000103997
fezf2
FEZ family zinc finger 2
chr23_-_36198253 0.19

chr5_-_13872772 0.19 ENSDART00000164698
CT009570.1
ENSDARG00000104490
chr15_-_5732737 0.18 ENSDART00000109599
urb1
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
chr16_+_31890895 0.18 ENSDART00000159821
atn1
atrophin 1
chr16_-_21973243 0.18 ENSDART00000039381
cops7a
COP9 constitutive photomorphogenic homolog subunit 7A
chr1_-_18581114 0.17 ENSDART00000178278
BX546494.1
ENSDARG00000107606
chr2_-_27065203 0.17 ENSDART00000148110
si:dkey-181m9.8
si:dkey-181m9.8
chr1_+_9634016 0.16 ENSDART00000029774
tmem55bb
transmembrane protein 55Bb
chr4_-_15442709 0.15 ENSDART00000157414
plxna4
plexin A4
chr18_+_1353857 0.14 ENSDART00000165301
rab27a
RAB27A, member RAS oncogene family
chr17_-_45036982 0.12 ENSDART00000155043
tmed8
transmembrane p24 trafficking protein 8
chr24_-_14447136 0.12

chr1_-_8439215 0.12 ENSDART00000081337
ndufab1a
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1a
chr3_-_28120760 0.12

chr9_+_41910191 0.12

chr11_+_38013238 0.12 ENSDART00000171496
CDK18
cyclin dependent kinase 18
chr4_+_11465367 0.12 ENSDART00000008584
gdi2
GDP dissociation inhibitor 2
chr17_-_44446275 0.09 ENSDART00000165252
slc35f4
solute carrier family 35, member F4
chr18_-_46279307 0.09

chr18_-_36787879 0.08

chr3_-_34431797 0.08 ENSDART00000129313
sept9a
septin 9a
chr8_-_21110428 0.06 ENSDART00000135938
cpt2
carnitine palmitoyltransferase 2
chr6_+_16342020 0.03 ENSDART00000114667
zgc:161969
zgc:161969
chr12_-_20493683 0.01

chr20_+_54595334 0.00

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.7 2.2 GO:0010084 specification of organ axis polarity(GO:0010084)
0.4 1.2 GO:0021742 abducens nucleus development(GO:0021742)
0.4 1.2 GO:0097484 dendrite extension(GO:0097484)
0.4 2.5 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.3 1.2 GO:0099558 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.3 2.4 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.3 2.4 GO:0060325 face morphogenesis(GO:0060325)
0.2 2.2 GO:0003315 heart rudiment formation(GO:0003315)
0.2 1.5 GO:0018057 peptidyl-lysine oxidation(GO:0018057) protein oxidation(GO:0018158)
0.2 0.7 GO:0030431 temperature homeostasis(GO:0001659) sleep(GO:0030431)
0.2 0.6 GO:0019884 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.2 1.5 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.2 1.2 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.2 1.7 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.1 0.9 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 1.4 GO:0015671 oxygen transport(GO:0015671)
0.1 1.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 1.0 GO:0042572 retinol metabolic process(GO:0042572)
0.1 1.6 GO:0032418 lysosome localization(GO:0032418)
0.1 5.2 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.1 1.7 GO:0006825 copper ion transport(GO:0006825)
0.1 0.8 GO:0050919 negative chemotaxis(GO:0050919)
0.1 0.8 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 3.0 GO:0060037 pharyngeal system development(GO:0060037)
0.1 1.2 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.5 GO:0043049 otic placode formation(GO:0043049)
0.0 0.9 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.0 GO:0001843 neural tube closure(GO:0001843)
0.0 0.2 GO:0051963 regulation of synapse assembly(GO:0051963) positive regulation of synapse assembly(GO:0051965)
0.0 0.9 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.3 GO:0036065 fucosylation(GO:0036065)
0.0 1.3 GO:0051693 regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835) actin filament capping(GO:0051693)
0.0 0.5 GO:0006595 polyamine metabolic process(GO:0006595)
0.0 0.8 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.7 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.6 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 2.1 GO:0030833 regulation of actin filament polymerization(GO:0030833)
0.0 1.2 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.3 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.3 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.0 GO:0030643 cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320) cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0008091 spectrin(GO:0008091)
0.2 1.2 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.2 1.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.2 1.4 GO:0005833 hemoglobin complex(GO:0005833) haptoglobin-hemoglobin complex(GO:0031838)
0.1 1.0 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 2.4 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.8 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 1.7 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 1.2 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.6 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.2 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 0.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.4 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.0 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 2.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 7.0 GO:0005887 integral component of plasma membrane(GO:0005887)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.3 1.2 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.2 1.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 3.1 GO:0038191 neuropilin binding(GO:0038191)
0.2 2.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 3.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 1.4 GO:0031720 haptoglobin binding(GO:0031720)
0.2 1.7 GO:0016531 copper chaperone activity(GO:0016531)
0.2 2.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 1.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 2.7 GO:0005112 Notch binding(GO:0005112)
0.1 0.5 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 1.1 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.1 1.4 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 1.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.8 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.5 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 0.8 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 2.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 4.0 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.1 GO:0044620 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0 2.2 GO:0019838 growth factor binding(GO:0019838)
0.0 1.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.6 GO:0045296 cadherin binding(GO:0045296)
0.0 0.0 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.9 GO:0031490 chromatin DNA binding(GO:0031490)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.6 PID E2F PATHWAY E2F transcription factor network
0.0 1.0 PID TNF PATHWAY TNF receptor signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 2.2 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing