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Results for prdm1a

Z-value: 0.92

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Transcription factors associated with prdm1a

Gene Symbol Gene ID Gene Info
prdm1a
ENSDARG00000002445 PR domain containing 1a, with ZNF domain

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
prdm1adr10_dc_chr16_-_7525980_75260510.802.3e-04Click!

Activity profile of prdm1a motif

Sorted Z-values of prdm1a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of prdm1a

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_-_40894631 2.69 ENSDART00000121840
eef2l2
eukaryotic translation elongation factor 2, like 2
chr24_-_39722595 2.51 ENSDART00000066506
cox6b1
cytochrome c oxidase subunit VIb polypeptide 1
chr22_+_33177432 2.46 ENSDART00000126885
dag1
dystroglycan 1
chr15_-_35563367 2.46

chr7_-_8635687 2.31 ENSDART00000081620
vax2
ventral anterior homeobox 2
chr15_+_40707917 2.15 ENSDART00000154187
ENSDART00000042082
fat3a
FAT atypical cadherin 3a
chr7_-_35438739 2.12 ENSDART00000043857
irx5a
iroquois homeobox 5a
chr11_+_21749658 2.10 ENSDART00000161485
foxp4
forkhead box P4
chr6_-_39315024 2.10 ENSDART00000012644
krt4
keratin 4
chr1_-_44009572 1.97 ENSDART00000144900
ENSDARG00000079632
ENSDARG00000079632
chr8_+_23716843 1.97 ENSDART00000136547
rpl10a
ribosomal protein L10a
chr22_+_30234718 1.87 ENSDART00000172496
add3a
adducin 3 (gamma) a
chr23_+_2391223 1.84

chr9_-_22140954 1.82 ENSDART00000146528
lmo7a
LIM domain 7a
chr13_+_30781652 1.82 ENSDART00000133138
drgx
dorsal root ganglia homeobox
chr8_+_39964695 1.81 ENSDART00000073782
ggt5a
gamma-glutamyltransferase 5a
chr8_+_15968469 1.81 ENSDART00000134787
elavl4
ELAV like neuron-specific RNA binding protein 4
chr10_-_35036872 1.80 ENSDART00000170625
smad9
SMAD family member 9
chr25_-_22890657 1.76

chr16_+_42925950 1.75 ENSDART00000159730
ENSDART00000014956
polr3glb
polymerase (RNA) III (DNA directed) polypeptide G like b
chr21_-_20674965 1.65 ENSDART00000065649
ENSDARG00000044676
ENSDARG00000044676
chr6_+_17959219 1.61 ENSDART00000026448
evpla
envoplakin a
chr6_-_58152436 1.55 ENSDART00000170752
tox2
TOX high mobility group box family member 2
chr10_-_42032702 1.52

chr18_-_15405161 1.50 ENSDART00000031752
rfx4
regulatory factor X, 4
chr12_+_32936230 1.47 ENSDART00000153146
rbfox3a
RNA binding protein, fox-1 homolog (C. elegans) 3a
chr25_+_222244 1.45 ENSDART00000155344
ENSDARG00000073905
ENSDARG00000073905
chr20_-_20502615 1.45

chr17_+_1058137 1.45

chr6_-_40660116 1.44 ENSDART00000154359
ppil1
peptidylprolyl isomerase (cyclophilin)-like 1
chr19_-_47366517 1.41 ENSDART00000043713
angpt1
angiopoietin 1
chr3_+_16826320 1.39 ENSDART00000112450
cavin1a
caveolae associated protein 1a
chr13_+_30781718 1.36 ENSDART00000133138
drgx
dorsal root ganglia homeobox
chr4_+_15870605 1.36 ENSDART00000178674
BX004864.1
ENSDARG00000107641
chr5_-_43334777 1.35 ENSDART00000142271
ENSDARG00000053091
ENSDARG00000053091
chr11_-_18542803 1.26 ENSDART00000059732
id1
inhibitor of DNA binding 1
chr2_-_43997672 1.25 ENSDART00000005449
zeb1a
zinc finger E-box binding homeobox 1a
chr8_-_50270783 1.24 ENSDART00000146056
nkx3-1
NK3 homeobox 1
chr16_-_43441084 1.21 ENSDART00000058680
psma2
proteasome subunit alpha 2
chr23_+_6298911 1.20 ENSDART00000139795
syt2a
synaptotagmin IIa
chr17_-_31041977 1.18 ENSDART00000104307
eml1
echinoderm microtubule associated protein like 1
chr16_+_5508950 1.17 ENSDART00000138674
plecb
plectin b
chr14_-_12531063 1.16 ENSDART00000165004
ENSDART00000043180
gria3b
glutamate receptor, ionotropic, AMPA 3b
chr5_-_63531729 1.15 ENSDART00000171711
gpsm1a
G protein signaling modulator 1a
chr12_+_5154886 1.14 ENSDART00000163897
lgi1b
leucine-rich, glioma inactivated 1b
chr4_+_5124186 1.09 ENSDART00000127874
ccnd2b
cyclin D2, b
chr3_-_23107763 1.07 ENSDART00000154058
AL929222.2
ENSDARG00000097738
chr19_+_9113356 1.04 ENSDART00000127755
ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr7_-_68229145 1.03

chr5_-_63422783 1.01 ENSDART00000083684
pappab
pregnancy-associated plasma protein A, pappalysin 1b
chr1_+_30974088 1.00 ENSDART00000144957
as3mt
arsenite methyltransferase
chr19_+_48582114 0.99 ENSDART00000157424
CU693379.1
ENSDARG00000098777
chr11_-_34367105 0.98 ENSDART00000157625
mapkapk3
mitogen-activated protein kinase-activated protein kinase 3
chr15_-_39756101 0.96

chr1_+_44009649 0.94 ENSDART00000131296
ssrp1b
structure specific recognition protein 1b
chr8_+_50953220 0.93 ENSDART00000124748
b2ml
beta-2-microglobulin, like
chr7_+_48597712 0.91 ENSDART00000009642
igf2a
insulin-like growth factor 2a
chr13_-_1021000 0.91 ENSDART00000007231
psmb1
proteasome subunit beta 1
chr11_-_25803101 0.91 ENSDART00000088888
kaznb
kazrin, periplakin interacting protein b
chr12_-_37124892 0.90 ENSDART00000146142
pmp22b
peripheral myelin protein 22b
chr14_+_20862466 0.89 ENSDART00000059796
ENSDARG00000019213
ENSDARG00000019213
chr7_-_27877036 0.89 ENSDART00000044208
lmo1
LIM domain only 1
chr8_+_39525254 0.89

chr7_+_65532390 0.89 ENSDART00000156683
CT573494.2
ENSDARG00000097673
chr23_-_27196543 0.86 ENSDART00000023218
ENSDART00000168175
ENSDART00000059346
stat6
signal transducer and activator of transcription 6, interleukin-4 induced
chr6_-_39315608 0.86 ENSDART00000012644
krt4
keratin 4
chr10_+_10252074 0.84 ENSDART00000144214
sh2d3ca
SH2 domain containing 3Ca
chr23_-_28286971 0.82

chr25_+_6858286 0.82

chr5_-_46382728 0.82

chr11_+_21749918 0.81 ENSDART00000161485
foxp4
forkhead box P4
chr24_+_37266599 0.80 ENSDART00000140412
si:dkey-224b4.5
si:dkey-224b4.5
chr11_-_38225034 0.80 ENSDART00000065613
elk4
ELK4, ETS-domain protein
chr3_-_12087518 0.80 ENSDART00000081374
cfap70
cilia and flagella associated protein 70
chr10_-_37098396 0.80 ENSDART00000155277
BX323076.2
ENSDARG00000097288
chr5_-_43686611 0.78 ENSDART00000146080
si:ch73-337l15.2
si:ch73-337l15.2
chr2_-_16586136 0.77 ENSDART00000133708
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr1_+_31210417 0.77 ENSDART00000007522
anos1a
anosmin 1a
chr23_-_3760604 0.77 ENSDART00000143731
pacsin1a
protein kinase C and casein kinase substrate in neurons 1a
chr7_-_8635989 0.76 ENSDART00000081620
vax2
ventral anterior homeobox 2
chr10_-_29930133 0.76 ENSDART00000055913
hist2h2l
histone 2, H2, like
chr7_+_37105282 0.75

chr7_+_26980284 0.75 ENSDART00000173962
sox6
SRY (sex determining region Y)-box 6
chr16_+_13964949 0.74 ENSDART00000143983
zgc:174888
zgc:174888
chr25_-_23648033 0.71 ENSDART00000089278
si:ch211-236l14.4
si:ch211-236l14.4
chr9_-_8475669 0.68 ENSDART00000110158
irs2b
insulin receptor substrate 2b
chr23_+_24778062 0.67

chr13_+_41885396 0.67 ENSDART00000131147
cyp1b1
cytochrome P450, family 1, subfamily B, polypeptide 1
chr15_-_1042743 0.67 ENSDART00000154195
si:dkey-77f5.6
si:dkey-77f5.6
chr20_-_47576935 0.66 ENSDART00000067776
rab10
RAB10, member RAS oncogene family
chr11_-_16067646 0.66

chr13_+_41885308 0.64 ENSDART00000126013
cyp1b1
cytochrome P450, family 1, subfamily B, polypeptide 1
chr7_-_68229018 0.64

chr9_-_19951894 0.64 ENSDART00000146841
si:ch211-141e20.2
si:ch211-141e20.2
chr18_-_14723138 0.64 ENSDART00000010129
pdf
peptide deformylase (mitochondrial)
chr22_-_23641813 0.64 ENSDART00000159622
cfh
complement factor H
chr16_-_49282668 0.62

chr14_-_4014025 0.61 ENSDART00000157782
irf2
interferon regulatory factor 2
chr18_-_18554151 0.61 ENSDART00000126460
il34
interleukin 34
chr11_-_1792616 0.60

chr3_-_34417082 0.59 ENSDART00000166623
sept9a
septin 9a
chr10_-_210681 0.58 ENSDART00000059476
psmg1
proteasome (prosome, macropain) assembly chaperone 1
chr18_+_14725148 0.56 ENSDART00000146128
uri1
URI1, prefoldin-like chaperone
chr8_+_15968636 0.56 ENSDART00000141173
elavl4
ELAV like neuron-specific RNA binding protein 4
chr8_+_22470384 0.56 ENSDART00000125805
si:ch211-261n11.8
si:ch211-261n11.8
chr4_+_17535295 0.55 ENSDART00000172169
ENSDART00000021610
recql
RecQ helicase-like
chr8_-_14338087 0.55 ENSDART00000090306
xpr1a
xenotropic and polytropic retrovirus receptor 1a
chr11_-_38225208 0.55 ENSDART00000102850
elk4
ELK4, ETS-domain protein
chr17_+_860032 0.55 ENSDART00000160400
gchfr
GTP cyclohydrolase I feedback regulator
chr14_-_46645127 0.52

chr10_+_7043530 0.52

chr4_-_9666436 0.51 ENSDART00000133214
dmtf1
cyclin D binding myb-like transcription factor 1
chr12_-_16331781 0.51 ENSDART00000152133
hectd2
HECT domain containing 2
chr24_+_17056023 0.51 ENSDART00000149225
mllt10
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10
chr18_+_50279433 0.49 ENSDART00000143911
si:dkey-105e17.1
si:dkey-105e17.1
chr20_+_4750766 0.49 ENSDART00000153486
lgals8a
galectin 8a
chr6_-_39313420 0.49

chr4_-_74789596 0.48 ENSDART00000174356
ENSDART00000174313
si:ch73-158p21.3
si:ch73-158p21.3
chr9_-_22141138 0.47 ENSDART00000146528
lmo7a
LIM domain 7a
chr8_-_14014576 0.46 ENSDART00000135811
atp2b3a
ATPase, Ca++ transporting, plasma membrane 3a
chr20_-_51585893 0.46 ENSDART00000151426
si:ch73-91k6.2
si:ch73-91k6.2
chr8_-_27839244 0.45 ENSDART00000136562
cttnbp2nlb
CTTNBP2 N-terminal like b
chr5_-_42304154 0.44 ENSDART00000112807
cxcl20
chemokine (C-X-C motif) ligand 20
chr4_+_17535561 0.42 ENSDART00000101198
recql
RecQ helicase-like
chr11_-_38280444 0.42

chr25_-_7585373 0.42 ENSDART00000157076
prdm11
PR domain containing 11
chr23_+_35405877 0.42 ENSDART00000159218
acp1
acid phosphatase 1, soluble
chr13_-_49921086 0.41 ENSDART00000165066
eif2ak2
eukaryotic translation initiation factor 2-alpha kinase 2
chr10_+_10252239 0.40 ENSDART00000144214
sh2d3ca
SH2 domain containing 3Ca
chr7_+_37105966 0.40 ENSDART00000111842
sall1a
spalt-like transcription factor 1a
chr22_-_23721742 0.39 ENSDART00000163228
cfh
complement factor H
chr5_-_14990023 0.39

chr23_+_24778090 0.38

chr14_+_21388983 0.37 ENSDART00000137589
ran
RAN, member RAS oncogene family
chr19_-_32900108 0.35 ENSDART00000050130
gmpr
guanosine monophosphate reductase
chr23_+_2391317 0.35

chr25_-_23648222 0.33 ENSDART00000089278
si:ch211-236l14.4
si:ch211-236l14.4
chr6_+_24561921 0.33 ENSDART00000169283
znf644b
zinc finger protein 644b
chr7_+_65532771 0.33 ENSDART00000082740
CT573494.2
ENSDARG00000097673
chr22_+_2253153 0.32 ENSDART00000133751
AL929017.2
ENSDARG00000095449
chr11_-_38280529 0.32

chr16_+_7874573 0.31

chr5_+_58824344 0.29 ENSDART00000148727
gtf2ird1
GTF2I repeat domain containing 1
chr3_-_19847002 0.29

chr19_+_8693914 0.28 ENSDART00000144925
snx27a
sorting nexin family member 27a
chr14_-_46645261 0.28

chr7_+_65532871 0.26 ENSDART00000082740
CT573494.2
ENSDARG00000097673
chr10_+_28700844 0.25 ENSDART00000047776
cblb
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr8_+_39964882 0.24 ENSDART00000134452
ggt5a
gamma-glutamyltransferase 5a
chr14_+_10795333 0.23

chr11_-_34366745 0.23 ENSDART00000157625
mapkapk3
mitogen-activated protein kinase-activated protein kinase 3
chr4_-_22617898 0.22 ENSDART00000131402
golgb1
golgin B1
chr9_+_8475950 0.21

chr18_+_50279394 0.21 ENSDART00000143911
si:dkey-105e17.1
si:dkey-105e17.1
chr19_-_35642784 0.21 ENSDART00000167853
ENSDART00000054274
macf1a
microtubule-actin crosslinking factor 1a
chr11_-_44223754 0.20 ENSDART00000172828
mfn1b
mitofusin 1b
chr4_+_22617563 0.20

chr9_-_15236879 0.17 ENSDART00000137043
ENSDART00000131512
pard3bb
par-3 family cell polarity regulator beta b
chr25_-_29914241 0.17 ENSDART00000171137
pdia3
protein disulfide isomerase family A, member 3
chr4_+_672670 0.16 ENSDART00000169748
fbxo7
F-box protein 7
chr20_-_27038165 0.16 ENSDART00000160827
ftr79
finTRIM family, member 79
chr9_-_32803650 0.16

chr23_-_7048903 0.15 ENSDART00000149656
edem2
ER degradation enhancer, mannosidase alpha-like 2
chr24_+_24777962 0.14 ENSDART00000065288
pcyt1ba
phosphate cytidylyltransferase 1, choline, beta a
chr7_-_32511304 0.13 ENSDART00000052497
gas2b
growth arrest-specific 2b
chr1_-_18084246 0.12

chr3_-_41369324 0.12

chr2_+_42155813 0.12 ENSDART00000143562
gbp2
guanylate binding protein 2
chr10_-_31334198 0.09 ENSDART00000134866
pknox2
pbx/knotted 1 homeobox 2
chr13_-_49920975 0.09 ENSDART00000165066
eif2ak2
eukaryotic translation initiation factor 2-alpha kinase 2
chr24_+_9740818 0.06 ENSDART00000036204
cdv3
carnitine deficiency-associated gene expressed in ventricle 3
chr13_-_43503505 0.06 ENSDART00000127930
ENSDART00000084474
fam160b1
family with sequence similarity 160, member B1
chr5_-_41044841 0.06 ENSDART00000051092
riok2
RIO kinase 2 (yeast)
chr7_-_37292692 0.05 ENSDART00000149052
nod2
nucleotide-binding oligomerization domain containing 2
chr22_-_8479330 0.05 ENSDART00000140146
ENSDART00000136891
si:ch73-27e22.3
si:ch73-27e22.3
chr25_-_22242337 0.02

chr19_+_7196277 0.02 ENSDART00000001359
psmb12
proteasome subunit beta 12
chr4_-_6365088 0.01 ENSDART00000140100
MDFIC
MyoD family inhibitor domain containing
chr19_+_12430505 0.00 ENSDART00000052240
psmg2
proteasome (prosome, macropain) assembly chaperone 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0006751 glutathione catabolic process(GO:0006751)
0.4 1.2 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.4 1.5 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.3 2.1 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.3 3.1 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259) negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.2 1.0 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.2 0.4 GO:0036230 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.2 0.9 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.2 0.6 GO:0014005 microglia development(GO:0014005)
0.2 1.4 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.1 0.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.6 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 1.3 GO:0042572 retinol metabolic process(GO:0042572)
0.1 1.2 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 0.4 GO:0006404 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.1 2.0 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 0.8 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 0.7 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.1 0.9 GO:0042102 positive regulation of mononuclear cell proliferation(GO:0032946) positive regulation of T cell proliferation(GO:0042102) positive regulation of lymphocyte proliferation(GO:0050671) positive regulation of leukocyte proliferation(GO:0070665)
0.1 0.6 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 1.1 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 3.0 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.1 1.9 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 0.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 1.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.7 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.8 GO:0097320 membrane tubulation(GO:0097320) positive regulation of dendrite development(GO:1900006)
0.1 0.2 GO:1903146 regulation of mitophagy(GO:1903146)
0.1 1.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 2.7 GO:0006414 translational elongation(GO:0006414)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.9 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 1.3 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 1.4 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 0.6 GO:0006817 phosphate ion transport(GO:0006817)
0.0 1.8 GO:0071559 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 0.4 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 1.1 GO:0048854 brain morphogenesis(GO:0048854)
0.0 2.3 GO:0030155 regulation of cell adhesion(GO:0030155)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 1.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.7 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 1.2 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.0 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.0 0.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 1.2 GO:0009416 response to light stimulus(GO:0009416)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0016586 RSC complex(GO:0016586)
0.2 0.7 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.9 GO:0035101 FACT complex(GO:0035101)
0.1 0.3 GO:1902560 GMP reductase complex(GO:1902560)
0.1 1.2 GO:0030056 hemidesmosome(GO:0030056)
0.1 1.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.9 GO:0045095 keratin filament(GO:0045095)
0.1 2.4 GO:0043204 perikaryon(GO:0043204)
0.1 1.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.2 GO:0032019 mitochondrial cloud(GO:0032019)
0.0 2.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.9 GO:0005839 proteasome core complex(GO:0005839)
0.0 1.4 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 1.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 1.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.2 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.2 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.2 GO:0005801 cis-Golgi network(GO:0005801)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.4 1.3 GO:0070330 aromatase activity(GO:0070330)
0.3 1.4 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.3 1.6 GO:0019215 intermediate filament binding(GO:0019215)
0.2 1.0 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.2 1.0 GO:0036310 annealing helicase activity(GO:0036310)
0.2 1.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.6 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 1.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.1 0.3 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.9 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 1.2 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.5 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.9 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 2.7 GO:0043022 ribosome binding(GO:0043022)
0.1 0.7 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.4 GO:0042379 chemokine activity(GO:0008009) chemokine receptor binding(GO:0042379)
0.0 2.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.0 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.2 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.6 GO:0005126 cytokine receptor binding(GO:0005126)
0.0 0.0 GO:0050700 CARD domain binding(GO:0050700)
0.0 1.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 16.4 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.3 PID ALK1 PATHWAY ALK1 signaling events
0.1 0.9 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 2.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 0.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.8 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 1.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 0.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 2.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 2.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.0 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.9 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.4 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle