Project

DANIO-CODE

Navigation
Downloads

Results for prdm2a

Z-value: 5.70

Motif logo

logo of

Transcription factors associated with prdm2a

Gene Symbol Gene ID Gene Info
prdm2a
ENSDARG00000090721 PR domain containing 2, with ZNF domain a

Activity profile of prdm2a motif

Sorted Z-values of prdm2a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of prdm2a

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr4_-_24310846 14.08 ENSDART00000017443
celf2
cugbp, Elav-like family member 2
chr7_+_39173765 13.86 ENSDART00000173748
tnnt3b
troponin T type 3b (skeletal, fast)
chr6_+_33556031 13.48 ENSDART00000147625
pik3r3b
phosphoinositide-3-kinase, regulatory subunit 3b (gamma)
chr20_+_31366832 11.59 ENSDART00000133353
apobb.1
apolipoprotein Bb, tandem duplicate 1
chr23_-_9556986 11.57 ENSDART00000139688
soga1
suppressor of glucose, autophagy associated 1
chr13_-_49826330 10.95 ENSDART00000099475
nid1a
nidogen 1a
chr15_-_2677200 10.92 ENSDART00000063320
cldne
claudin e
chr23_-_35595271 10.92 ENSDART00000164616
tuba1c
tubulin, alpha 1c
chr14_+_20809272 10.77 ENSDART00000139865
aldob
aldolase b, fructose-bisphosphate
chr13_-_18704185 10.72 ENSDART00000146795
lzts2a
leucine zipper, putative tumor suppressor 2a
chr21_-_1716495 10.24 ENSDART00000151049
onecut2
one cut homeobox 2
chr6_-_43094573 10.06 ENSDART00000084389
lrrn1
leucine rich repeat neuronal 1
chr5_+_59845054 10.02 ENSDART00000130565
tmem132e
transmembrane protein 132E
chr5_+_59844830 9.66 ENSDART00000130565
tmem132e
transmembrane protein 132E
chr15_-_9026081 9.66 ENSDART00000126708
rhoub
ras homolog family member Ub
chr3_-_6078015 9.64 ENSDART00000165715
BX284638.1
ENSDARG00000098850
chr18_+_5899355 9.37

chr18_+_6551983 9.31 ENSDART00000160382
ENSDART00000171495
ENSDART00000160228
fam168a
family with sequence similarity 168, member A
chr17_+_28690237 8.96 ENSDART00000126967
strn3
striatin, calmodulin binding protein 3
chr6_+_33556155 8.95 ENSDART00000147625
pik3r3b
phosphoinositide-3-kinase, regulatory subunit 3b (gamma)
chr2_+_24881103 8.88 ENSDART00000144149
angptl4
angiopoietin-like 4
chr15_-_2689005 8.71 ENSDART00000063325
cldnf
claudin f
chr22_+_37944019 8.69

chr7_-_28425307 8.56 ENSDART00000148822
adgrg1
adhesion G protein-coupled receptor G1
chr13_-_7434672 8.49 ENSDART00000159453
h2afy2
H2A histone family, member Y2
chr14_+_35885903 8.44 ENSDART00000052569
pitx2
paired-like homeodomain 2
chr9_-_3429153 8.42 ENSDART00000111386
dlx2a
distal-less homeobox 2a
chr14_-_46359062 8.39 ENSDART00000090844
zgc:153018
zgc:153018
chr23_-_27226280 8.36 ENSDART00000141305
si:dkey-157g16.6
si:dkey-157g16.6
chr17_-_49878964 8.32 ENSDART00000154728
col12a1a
collagen, type XII, alpha 1a
chr14_+_34683602 8.18 ENSDART00000172171
ebf1a
early B-cell factor 1a
chr7_+_6814828 7.92 ENSDART00000001649
actn3b
actinin alpha 3b
chr2_-_39710140 7.81 ENSDART00000147821
spsb4a
splA/ryanodine receptor domain and SOCS box containing 4a
chr6_+_55022668 7.77 ENSDART00000158845
mybphb
myosin binding protein Hb
chr10_-_26468280 7.76 ENSDART00000128894
dchs1b
dachsous cadherin-related 1b
chr25_-_10992022 7.74 ENSDART00000154748
sv2bb
synaptic vesicle glycoprotein 2Bb
chr3_-_54866453 7.70 ENSDART00000125092
hbae1
hemoglobin, alpha embryonic 1
chr4_+_8531280 7.70 ENSDART00000162065
wnt5b
wingless-type MMTV integration site family, member 5b
chr12_+_32936230 7.61 ENSDART00000153146
rbfox3a
RNA binding protein, fox-1 homolog (C. elegans) 3a
chr1_+_50277442 7.61 ENSDART00000150420
otx1a
orthodenticle homeobox 1a
chr19_-_35739239 7.58

KN149968v1_+_15749 7.56 ENSDART00000168977
ENSDARG00000102503
ENSDARG00000102503
chr7_-_8635687 7.49 ENSDART00000081620
vax2
ventral anterior homeobox 2
chr8_-_30233470 7.48 ENSDART00000139864
zgc:162939
zgc:162939
chr23_+_42381296 7.46 ENSDART00000158684
ENSDART00000159985
ENSDART00000172144
cyp2aa11
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr15_+_38957922 7.40 ENSDART00000141086
robo2
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr4_-_16556116 7.36 ENSDART00000033188
btg1
B-cell translocation gene 1, anti-proliferative
chr10_-_11806373 7.36 ENSDART00000009715
adamts6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr9_+_53788118 7.35 ENSDART00000125715
ENSDART00000166582
ENSDART00000162224
dct
dopachrome tautomerase
chr11_-_4216204 7.33 ENSDART00000121716
ENSDARG00000086300
ENSDARG00000086300
chr23_-_18958008 7.33 ENSDART00000133419
CR847953.1
ENSDARG00000057403
chr23_-_29138952 7.26 ENSDART00000002812
casz1
castor zinc finger 1
chr20_+_4222097 7.21 ENSDART00000097543
im:7142702
im:7142702
chr9_+_26292183 7.14

chr7_+_22552724 7.14 ENSDART00000101459
ENSDART00000159743
pygmb
phosphorylase, glycogen, muscle b
chr5_+_53938629 7.13 ENSDART00000171225
npr2
natriuretic peptide receptor 2
chr3_-_30554400 7.10 ENSDART00000151097
si:ch211-51c14.1
si:ch211-51c14.1
chr10_-_25695574 6.97 ENSDART00000110751
tiam1a
T-cell lymphoma invasion and metastasis 1a
chr13_+_28601627 6.92 ENSDART00000015773
ldb1a
LIM domain binding 1a
chr16_+_53238110 6.87 ENSDART00000102170
CABZ01053976.1
ENSDARG00000069929
chr6_-_343209 6.81

chr19_+_7234029 6.77 ENSDART00000080348
brd2a
bromodomain containing 2a
chr1_-_48853800 6.77 ENSDART00000137357
zgc:175214
zgc:175214
chr10_+_9052152 6.75 ENSDART00000139466
itga2.2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 2
chr23_-_4990023 6.71 ENSDART00000142699
taz
tafazzin
chr13_-_43027245 6.57 ENSDART00000099601
ENSDARG00000068784
ENSDARG00000068784
chr9_+_54692834 6.53

chr10_-_36462538 6.53 ENSDART00000161823
ubl3a
ubiquitin-like 3a
chr24_-_9151388 6.53 ENSDART00000149875
tgif1
TGFB-induced factor homeobox 1
chr13_+_41998500 6.53 ENSDART00000074707
cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr14_-_4166292 6.49 ENSDART00000127318
frmpd1b
FERM and PDZ domain containing 1b
chr8_+_28584427 6.47 ENSDART00000097213
tcf15
transcription factor 15
chr2_-_59531831 6.43 ENSDART00000168568
CU861477.1
ENSDARG00000100128
chr16_-_17164459 6.40 ENSDART00000178443
tnfrsf1a
tumor necrosis factor receptor superfamily, member 1a
chr10_+_3728747 6.39

chr25_+_35901081 6.37 ENSDART00000042271
ENSDART00000158027
irx3b
iroquois homeobox 3b
chr6_-_12487617 6.35 ENSDART00000090174
dock9b
dedicator of cytokinesis 9b
chr3_+_31542311 6.32

chr20_+_54512601 6.31 ENSDART00000169386
faua
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed a
chr4_+_7668939 6.26 ENSDART00000149218
elk3
ELK3, ETS-domain protein
chr16_-_31763183 6.25 ENSDART00000169109
rbp5
retinol binding protein 1a, cellular
chr24_-_21114505 6.21 ENSDART00000111025
boc
BOC cell adhesion associated, oncogene regulated
chr2_-_30340646 6.17 ENSDART00000099078
jph1b
junctophilin 1b
chr6_-_19928053 6.15 ENSDART00000161257
plxnb1b
plexin b1b
chr9_-_32942783 6.08 ENSDART00000060006
olig2
oligodendrocyte lineage transcription factor 2
chr8_+_15989815 5.99 ENSDART00000110171
elavl4
ELAV like neuron-specific RNA binding protein 4
KN149932v1_+_27584 5.95

chr5_+_37053530 5.92 ENSDART00000161051
sptbn2
spectrin, beta, non-erythrocytic 2
chr25_-_4376129 5.92

chr7_+_58718614 5.91 ENSDART00000157873
hacd1
3-hydroxyacyl-CoA dehydratase 1
chr3_+_22412059 5.90

chr23_-_27226387 5.87 ENSDART00000141305
si:dkey-157g16.6
si:dkey-157g16.6
chr12_+_689413 5.85 ENSDART00000174804
abcc3
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr16_+_54906517 5.85 ENSDART00000126646
ENSDARG00000091079
ENSDARG00000091079
chr20_-_9212177 5.84 ENSDART00000064140
ylpm1
YLP motif containing 1
chr25_-_36760720 5.83 ENSDART00000111862
ldlrad3
low density lipoprotein receptor class A domain containing 3
chr22_-_22694468 5.82 ENSDART00000166794
nr5a2
nuclear receptor subfamily 5, group A, member 2
chr25_+_30746445 5.79 ENSDART00000156916
lsp1
lymphocyte-specific protein 1
chr20_-_6822668 5.75 ENSDART00000169569
igfbp1a
insulin-like growth factor binding protein 1a
chr10_-_32580145 5.75 ENSDART00000137608
dgat2
diacylglycerol O-acyltransferase 2
chr2_-_816669 5.72 ENSDART00000122732
foxc1a
forkhead box C1a
chr5_-_36349284 5.70 ENSDART00000047269
h3f3b.1
H3 histone, family 3B.1
chr14_-_2008649 5.65 ENSDART00000161817
pcdh2g16
protocadherin 2 gamma 16
chr3_-_7769397 5.61

chr3_-_35928594 5.60

chr8_+_26103807 5.59

chr9_+_46038777 5.59 ENSDART00000114814
twist2
twist2
chr16_-_53896201 5.56 ENSDART00000179533
fzd1
frizzled class receptor 1
chr10_+_10252074 5.53 ENSDART00000144214
sh2d3ca
SH2 domain containing 3Ca
chr7_-_32888309 5.53 ENSDART00000173461
BX571811.2
ENSDARG00000105655
chr8_-_4451417 5.50 ENSDART00000141915
si:ch211-166a6.5
si:ch211-166a6.5
chr1_-_4696894 5.50 ENSDART00000103724
ndfip2
Nedd4 family interacting protein 2
chr25_-_33670713 5.49 ENSDART00000125036
foxb1a
forkhead box B1a
chr21_-_43020159 5.47 ENSDART00000065097
dpysl3
dihydropyrimidinase-like 3
chr22_-_17652938 5.43 ENSDART00000139911
tjp3
tight junction protein 3
chr21_-_9708608 5.42

chr20_-_21773202 5.41 ENSDART00000133286
si:ch211-207i1.2
si:ch211-207i1.2
chr4_+_11312432 5.39 ENSDART00000051792
sema3aa
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa
chr19_-_29205158 5.39 ENSDART00000026992
sox4a
SRY (sex determining region Y)-box 4a
chr18_+_7607055 5.38 ENSDART00000140784
CR318588.4
ENSDARG00000095556
chr4_+_14972708 5.38 ENSDART00000005985
smo
smoothened, frizzled class receptor
chr7_-_34656224 5.37 ENSDART00000073397
nfatc3a
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3a
chr12_+_11042472 5.36 ENSDART00000079336
raraa
retinoic acid receptor, alpha a
chr14_-_31128891 5.34

chr15_-_14616083 5.34 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr1_+_1953714 5.31 ENSDART00000164488
ENSDART00000167050
ENSDART00000122626
ENSDART00000128187
mbnl2
muscleblind-like splicing regulator 2
chr2_+_3701942 5.30 ENSDART00000132572
gpt2l
glutamic pyruvate transaminase (alanine aminotransferase) 2, like
chr22_+_5697877 5.26 ENSDART00000063484
si:dkey-222f2.1
si:dkey-222f2.1
chr2_-_35584440 5.25 ENSDART00000125298
tnw
tenascin W
chr3_+_59560881 5.24 ENSDART00000084738
ppp1r27a
protein phosphatase 1, regulatory subunit 27a
chr14_+_41805073 5.24 ENSDART00000074362
pcdh18b
protocadherin 18b
chr2_+_49837788 5.22 ENSDART00000108861
sema4e
semaphorin 4e
chr20_+_34640226 5.21 ENSDART00000076946
ENSDARG00000054723
ENSDARG00000054723
chr2_-_49114158 5.19

chr9_-_30243398 5.19 ENSDART00000139863
ENSDART00000140040
dcbld2
discoidin, CUB and LCCL domain containing 2
chr18_-_45892 5.17 ENSDART00000052641
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr23_-_41690232 5.16

chr7_-_56493164 5.16

chr5_+_62987426 5.15 ENSDART00000178937
dnm1b
dynamin 1b
chr23_+_42449144 5.14 ENSDART00000171119
cyp2aa9
cytochrome P450, family 2, subfamily AA, polypeptide 9
chr19_-_23037220 5.12 ENSDART00000090669
pleca
plectin a
chr14_-_16023198 5.12

chr3_+_12287067 5.10 ENSDART00000158060
vasnb
vasorin b
chr16_+_5625301 5.07

chr14_+_34683695 5.07 ENSDART00000170631
ebf1a
early B-cell factor 1a
chr20_-_54742983 5.04

chr2_+_33399405 5.04 ENSDART00000137207
slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr15_-_23587330 5.02 ENSDART00000167246
hmbsb
hydroxymethylbilane synthase, b
chr15_+_14918849 5.02 ENSDART00000164119
diabloa
diablo, IAP-binding mitochondrial protein a
chr20_+_7337738 5.01 ENSDART00000165596
dsg2.1
desmoglein 2, tandem duplicate 1
chr19_-_35512932 4.97

chr14_-_46359248 4.97 ENSDART00000090844
zgc:153018
zgc:153018
chr2_+_26523457 4.96 ENSDART00000024662
plppr3a
phospholipid phosphatase related 3a
chr18_-_45750 4.96 ENSDART00000148821
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr10_+_24476213 4.94 ENSDART00000146370
slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr20_-_26568204 4.93 ENSDART00000158213
akap12b
A kinase (PRKA) anchor protein 12b
chr16_-_13704905 4.92 ENSDART00000060004
ntd5
ntl-dependent gene 5
chr9_+_17341042 4.92 ENSDART00000147488
slain1a
SLAIN motif family, member 1a
chr19_-_35513216 4.91

chr11_-_471166 4.88 ENSDART00000154888
cnbpb
CCHC-type zinc finger, nucleic acid binding protein b
chr12_+_27370834 4.88 ENSDART00000105661
meox1
mesenchyme homeobox 1
chr6_-_27901354 4.83 ENSDART00000155116
im:7152348
im:7152348
chr3_-_30554490 4.81 ENSDART00000151097
si:ch211-51c14.1
si:ch211-51c14.1
chr10_-_32580373 4.79 ENSDART00000066793
dgat2
diacylglycerol O-acyltransferase 2
chr3_-_55995924 4.78 ENSDART00000167356
tfap4
transcription factor AP-4 (activating enhancer binding protein 4)
chr6_-_49674729 4.77 ENSDART00000112226
apcdd1l
adenomatosis polyposis coli down-regulated 1-like
chr22_+_24362712 4.74 ENSDART00000157861
p3h2
prolyl 3-hydroxylase 2
chr12_+_41016238 4.74 ENSDART00000170976
kif5bb
kinesin family member 5B, b
KN149955v1_+_4206 4.73 ENSDART00000167370
cdkn1d
cyclin-dependent kinase inhibitor 1D
chr20_+_26803282 4.72 ENSDART00000077753
foxc1b
forkhead box C1b
chr23_+_24711233 4.71

chr14_+_4810147 4.71 ENSDART00000114678
nanos1
nanos homolog 1
chr24_-_26165778 4.71 ENSDART00000080113
apodb
apolipoprotein Db
chr16_+_29060022 4.69 ENSDART00000088023
gon4l
gon-4-like (C. elegans)
chr24_-_14567403 4.69 ENSDART00000131830
jph1a
junctophilin 1a
KN149955v1_+_4134 4.67 ENSDART00000167370
cdkn1d
cyclin-dependent kinase inhibitor 1D
chr25_+_24152717 4.64 ENSDART00000064646
tmem86a
transmembrane protein 86A
chr19_+_14197118 4.62 ENSDART00000166230
tpbga
trophoblast glycoprotein a
chr19_+_1797470 4.62

chr2_+_49683715 4.60 ENSDART00000122742
ENSDART00000160783
rorcb
RAR-related orphan receptor C b
chr10_-_10374032 4.57 ENSDART00000134929
BX323065.1
ENSDARG00000095365
chr20_-_11111340 4.56

chr4_+_21166170 4.53 ENSDART00000036886
nav3
neuron navigator 3
chr3_-_10342940 4.51 ENSDART00000124419
BX539325.2
ENSDARG00000101154
chr12_+_18403055 4.50 ENSDART00000090332
neurl2
neuralized E3 ubiquitin protein ligase 2
chr6_-_12953515 4.50 ENSDART00000150036
ENSDART00000149940
adam23a
ADAM metallopeptidase domain 23a
chr4_-_19027117 4.49 ENSDART00000166160
si:dkey-31f5.11
si:dkey-31f5.11
chr23_+_18176720 4.46 ENSDART00000010270
mfsd4ab
major facilitator superfamily domain containing 4Ab
chr10_+_33462953 4.46 ENSDART00000137089
ryr1a
ryanodine receptor 1a (skeletal)
chr10_-_1799784 4.46 ENSDART00000058627
epb41l4a
erythrocyte membrane protein band 4.1 like 4A
chr3_+_24059652 4.44 ENSDART00000034762
prr15la
proline rich 15-like a
chr12_+_30448812 4.39 ENSDART00000126064
si:ch211-28p3.4
si:ch211-28p3.4
chr16_-_12579115 4.38 ENSDART00000147483
ephb6
eph receptor B6
chr23_+_2193582 4.36 ENSDART00000106336
cpeb2
cytoplasmic polyadenylation element binding protein 2
chr25_+_15551474 4.34 ENSDART00000137375
spon1b
spondin 1b
chr8_-_19311772 4.33 ENSDART00000138881
ENSDART00000010604
rgl1
ral guanine nucleotide dissociation stimulator-like 1
chr24_-_24001766 4.29 ENSDART00000173052
ENSDART00000173220
map7d2b
MAP7 domain containing 2b
chr11_-_27260783 4.28

chr6_-_14010044 4.28 ENSDART00000149177
ENSDART00000174839
ENSDART00000089577
cacnb4b
calcium channel, voltage-dependent, beta 4b subunit
chr21_+_21337628 4.27 ENSDART00000136325
rtn2b
reticulon 2b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 3.9 GO:0034369 protein-lipid complex remodeling(GO:0034368) plasma lipoprotein particle remodeling(GO:0034369)
3.7 11.1 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
3.5 10.5 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
3.5 10.5 GO:0008306 associative learning(GO:0008306) visual learning(GO:0008542) mammillary axonal complex development(GO:0061373) mammillothalamic axonal tract development(GO:0061374) corpora quadrigemina development(GO:0061378) inferior colliculus development(GO:0061379) cell migration in diencephalon(GO:0061381)
3.5 10.4 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
3.4 10.1 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
3.1 21.5 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
2.9 8.8 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
2.8 8.4 GO:1902869 negative regulation of photoreceptor cell differentiation(GO:0046533) regulation of amacrine cell differentiation(GO:1902869) positive regulation of amacrine cell differentiation(GO:1902871)
2.1 8.4 GO:0061072 iris morphogenesis(GO:0061072)
2.0 6.1 GO:0021742 abducens nucleus development(GO:0021742)
1.9 7.4 GO:0016199 axon midline choice point recognition(GO:0016199)
1.8 7.3 GO:0048103 cell proliferation in forebrain(GO:0021846) neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
1.8 5.5 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
1.8 5.5 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
1.8 7.2 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
1.7 9.9 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
1.6 12.4 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
1.5 22.4 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
1.5 3.0 GO:0015670 carbon dioxide transport(GO:0015670)
1.4 10.1 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
1.4 5.7 GO:0099565 chemical synaptic transmission, postsynaptic(GO:0099565)
1.4 4.1 GO:0048664 neuron fate determination(GO:0048664)
1.3 10.7 GO:0051013 microtubule severing(GO:0051013)
1.3 3.9 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
1.3 7.8 GO:0007343 egg activation(GO:0007343)
1.3 11.6 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
1.3 6.4 GO:0035777 pronephric distal tubule development(GO:0035777)
1.3 7.6 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
1.2 3.7 GO:0097376 interneuron axon guidance(GO:0097376) spinal cord interneuron axon guidance(GO:0097377) dorsal spinal cord interneuron axon guidance(GO:0097378)
1.2 3.7 GO:1903385 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
1.2 11.1 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
1.2 4.9 GO:1904969 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
1.2 8.1 GO:0030104 water homeostasis(GO:0030104)
1.1 13.7 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
1.1 6.7 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
1.1 3.3 GO:1903010 regulation of bone development(GO:1903010)
1.1 5.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
1.1 7.7 GO:0021523 somatic motor neuron differentiation(GO:0021523)
1.1 5.4 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
1.1 3.2 GO:0045475 locomotor rhythm(GO:0045475)
1.0 5.1 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
1.0 6.2 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
1.0 4.9 GO:0061056 sclerotome development(GO:0061056)
0.9 11.9 GO:0097320 membrane tubulation(GO:0097320)
0.9 11.0 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.9 4.5 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.9 0.9 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.8 6.7 GO:0046471 cardiolipin metabolic process(GO:0032048) phosphatidylglycerol metabolic process(GO:0046471)
0.8 19.6 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.7 20.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.7 6.9 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.7 2.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.7 2.7 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.7 3.3 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.7 13.9 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.7 5.9 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.6 15.3 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.6 3.2 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.6 9.9 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.6 3.0 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.6 1.8 GO:0032964 collagen biosynthetic process(GO:0032964)
0.6 3.5 GO:0006382 adenosine to inosine editing(GO:0006382)
0.6 6.9 GO:0044247 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.6 4.0 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.6 3.4 GO:0035094 response to nicotine(GO:0035094)
0.6 10.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.6 6.2 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.6 6.7 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.6 10.1 GO:0021602 cranial nerve morphogenesis(GO:0021602)
0.6 7.2 GO:0072576 liver morphogenesis(GO:0072576)
0.6 5.5 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.6 3.9 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.5 4.9 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.5 5.2 GO:0070527 platelet aggregation(GO:0070527)
0.5 8.7 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.5 2.5 GO:0019229 regulation of vasoconstriction(GO:0019229)
0.5 8.3 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.5 2.9 GO:2000765 regulation of cytoplasmic translation(GO:2000765)
0.5 5.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.5 2.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.4 3.1 GO:0045453 bone resorption(GO:0045453)
0.4 4.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.4 2.2 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.4 8.2 GO:0021871 forebrain regionalization(GO:0021871)
0.4 3.9 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.4 6.8 GO:0002574 thrombocyte differentiation(GO:0002574)
0.4 7.6 GO:0032526 response to retinoic acid(GO:0032526)
0.4 1.7 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.4 7.1 GO:0044259 collagen metabolic process(GO:0032963) multicellular organismal macromolecule metabolic process(GO:0044259)
0.4 9.3 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.4 3.1 GO:0097028 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011) dendritic cell differentiation(GO:0097028)
0.4 2.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.4 1.1 GO:0052803 imidazole-containing compound metabolic process(GO:0052803) imidazole-containing compound catabolic process(GO:0052805)
0.4 2.6 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.4 7.8 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.4 4.4 GO:0097178 ruffle assembly(GO:0097178)
0.4 6.9 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) nucleus localization(GO:0051647)
0.3 2.4 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.3 1.3 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.3 1.0 GO:0051965 regulation of synapse assembly(GO:0051963) positive regulation of synapse assembly(GO:0051965)
0.3 6.4 GO:0050727 regulation of inflammatory response(GO:0050727)
0.3 3.8 GO:0070831 basement membrane assembly(GO:0070831)
0.3 2.1 GO:0046549 retinal cone cell development(GO:0046549)
0.3 2.4 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.3 3.6 GO:0031581 cell-substrate junction assembly(GO:0007044) hemidesmosome assembly(GO:0031581)
0.3 3.8 GO:0045332 phospholipid translocation(GO:0045332)
0.3 3.2 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.3 5.8 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.3 1.6 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.3 3.8 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.3 5.8 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.3 1.6 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.3 18.5 GO:0007224 smoothened signaling pathway(GO:0007224)
0.3 1.3 GO:0002551 mast cell chemotaxis(GO:0002551) positive regulation of leukocyte chemotaxis(GO:0002690) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.3 8.4 GO:0009755 hormone-mediated signaling pathway(GO:0009755)
0.2 5.1 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.2 9.7 GO:0007160 cell-matrix adhesion(GO:0007160)
0.2 0.9 GO:0016264 gap junction assembly(GO:0016264)
0.2 1.8 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.2 3.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.2 2.0 GO:0021703 locus ceruleus development(GO:0021703)
0.2 3.0 GO:1990798 pancreas regeneration(GO:1990798)
0.2 7.7 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.2 8.3 GO:0030834 regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835) actin filament capping(GO:0051693)
0.2 3.2 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.2 3.3 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.2 22.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 5.9 GO:0030497 fatty acid elongation(GO:0030497)
0.2 1.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.2 6.6 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.2 2.6 GO:0010833 telomere maintenance via telomere lengthening(GO:0010833)
0.2 5.9 GO:0007050 cell cycle arrest(GO:0007050)
0.2 4.7 GO:0060349 bone morphogenesis(GO:0060349)
0.2 6.7 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.2 4.7 GO:0000302 response to reactive oxygen species(GO:0000302)
0.2 0.7 GO:0090299 regulation of neural crest formation(GO:0090299)
0.2 12.7 GO:0006836 neurotransmitter transport(GO:0006836)
0.2 5.5 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.2 2.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.2 1.4 GO:0032264 IMP salvage(GO:0032264)
0.2 11.6 GO:0010506 regulation of autophagy(GO:0010506)
0.1 7.7 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.1 0.8 GO:0002063 chondrocyte development(GO:0002063)
0.1 2.5 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 3.2 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 1.1 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 2.5 GO:0043627 response to estrogen(GO:0043627) cellular response to estrogen stimulus(GO:0071391)
0.1 3.7 GO:0007043 cell-cell junction assembly(GO:0007043)
0.1 6.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 2.2 GO:0015914 phospholipid transport(GO:0015914)
0.1 2.3 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 2.1 GO:0007416 synapse assembly(GO:0007416)
0.1 0.6 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.1 5.3 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.1 1.3 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.1 3.3 GO:0042742 defense response to bacterium(GO:0042742)
0.1 1.1 GO:0003323 type B pancreatic cell development(GO:0003323)
0.1 1.0 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 2.5 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 3.7 GO:0045010 actin nucleation(GO:0045010)
0.1 3.3 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.1 8.0 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.1 1.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 1.2 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 2.8 GO:0072175 epithelial tube formation(GO:0072175)
0.1 0.7 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 1.6 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.1 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 1.3 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 2.7 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.1 1.9 GO:0001946 lymphangiogenesis(GO:0001946)
0.1 7.1 GO:0045664 regulation of neuron differentiation(GO:0045664)
0.0 3.8 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.7 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 2.1 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 22.5 GO:0055085 transmembrane transport(GO:0055085)
0.0 3.3 GO:0006869 lipid transport(GO:0006869)
0.0 0.6 GO:0098781 ncRNA transcription(GO:0098781)
0.0 7.6 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 0.9 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 1.3 GO:0021782 glial cell development(GO:0021782)
0.0 4.3 GO:0007411 axon guidance(GO:0007411)
0.0 1.7 GO:1905037 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.1 GO:0021982 pineal gland development(GO:0021982)
0.0 1.1 GO:0098916 chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916)
0.0 6.0 GO:0008380 RNA splicing(GO:0008380)
0.0 0.3 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 3.3 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.0 1.1 GO:0048477 oogenesis(GO:0048477)
0.0 5.4 GO:0000226 microtubule cytoskeleton organization(GO:0000226)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.9 GO:0030314 junctional membrane complex(GO:0030314)
2.3 11.6 GO:0042627 chylomicron(GO:0042627)
1.7 8.3 GO:0008091 spectrin(GO:0008091)
1.4 5.5 GO:0032019 mitochondrial cloud(GO:0032019)
1.2 7.3 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
1.1 10.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
1.0 12.5 GO:0005640 nuclear outer membrane(GO:0005640)
1.0 5.1 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.9 6.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.9 2.6 GO:1990879 CST complex(GO:1990879)
0.7 4.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.6 13.9 GO:0005861 troponin complex(GO:0005861)
0.5 5.1 GO:0030056 hemidesmosome(GO:0030056)
0.4 4.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.4 4.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.4 1.3 GO:0071914 prominosome(GO:0071914)
0.4 22.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.4 8.3 GO:0005581 collagen trimer(GO:0005581)
0.3 3.8 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.3 26.0 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.3 11.5 GO:0030426 growth cone(GO:0030426)
0.3 7.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.3 8.9 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.3 7.8 GO:0016342 catenin complex(GO:0016342)
0.3 2.1 GO:0005921 gap junction(GO:0005921)
0.3 3.9 GO:0036038 MKS complex(GO:0036038)
0.3 5.6 GO:0045095 keratin filament(GO:0045095)
0.2 1.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 2.5 GO:0032783 ELL-EAF complex(GO:0032783)
0.2 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 3.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 1.5 GO:0005955 calcineurin complex(GO:0005955)
0.2 8.7 GO:0005604 basement membrane(GO:0005604)
0.2 2.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 3.2 GO:0071564 npBAF complex(GO:0071564)
0.2 1.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 26.9 GO:0031012 extracellular matrix(GO:0031012)
0.2 7.7 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 8.0 GO:0030496 midbody(GO:0030496)
0.2 6.9 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.2 6.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 71.7 GO:0005615 extracellular space(GO:0005615)
0.1 9.4 GO:0043235 receptor complex(GO:0043235)
0.1 15.7 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 64.1 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 2.5 GO:0005844 polysome(GO:0005844)
0.1 2.8 GO:0048786 presynaptic active zone(GO:0048786)
0.1 3.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 24.1 GO:0005576 extracellular region(GO:0005576)
0.1 3.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 3.7 GO:0030141 secretory granule(GO:0030141)
0.1 9.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 1.6 GO:0031225 anchored component of membrane(GO:0031225)
0.1 4.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 10.7 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.1 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.7 GO:0016605 PML body(GO:0016605)
0.0 2.1 GO:0005643 nuclear pore(GO:0005643)
0.0 3.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 3.9 GO:0005740 mitochondrial envelope(GO:0005740) mitochondrial membrane(GO:0031966)
0.0 4.9 GO:0005929 cilium(GO:0005929)
0.0 3.4 GO:0043005 neuron projection(GO:0043005)
0.0 2.5 GO:0005884 actin filament(GO:0005884)
0.0 1.0 GO:0009986 cell surface(GO:0009986)
0.0 0.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 22.4 GO:0005886 plasma membrane(GO:0005886)
0.0 3.5 GO:0005730 nucleolus(GO:0005730)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.7 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
3.3 9.9 GO:0004383 guanylate cyclase activity(GO:0004383)
2.0 5.9 GO:0102344 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
1.9 9.5 GO:0005035 death receptor activity(GO:0005035)
1.8 7.1 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
1.7 13.9 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
1.7 6.9 GO:0030274 LIM domain binding(GO:0030274)
1.7 6.7 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
1.7 11.6 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
1.5 6.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
1.4 10.0 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
1.4 6.9 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
1.3 5.4 GO:0008142 oxysterol binding(GO:0008142)
1.3 10.5 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
1.3 7.8 GO:0016918 retinal binding(GO:0016918)
1.2 4.6 GO:0016803 ether hydrolase activity(GO:0016803)
1.1 11.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
1.0 5.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.9 6.3 GO:0005355 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.9 3.5 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.9 7.8 GO:0048495 Roundabout binding(GO:0048495)
0.8 3.4 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.8 4.2 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.8 2.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.8 5.5 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.8 3.9 GO:0017040 ceramidase activity(GO:0017040)
0.7 4.5 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.7 3.6 GO:0004565 beta-galactosidase activity(GO:0004565)
0.7 7.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.7 22.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.7 7.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.7 2.1 GO:0005243 gap junction channel activity(GO:0005243)
0.7 6.9 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.7 5.5 GO:0050699 WW domain binding(GO:0050699)
0.7 3.3 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.7 5.9 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.6 3.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.6 3.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.6 3.0 GO:0008515 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.6 3.5 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.5 4.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.5 24.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.5 5.0 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.5 2.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.5 17.5 GO:0005109 frizzled binding(GO:0005109)
0.5 10.1 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.5 9.6 GO:0030371 translation repressor activity(GO:0030371)
0.5 18.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.5 1.4 GO:0030553 cGMP-dependent protein kinase activity(GO:0004692) cGMP binding(GO:0030553)
0.4 2.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.4 10.7 GO:0008013 beta-catenin binding(GO:0008013)
0.4 5.4 GO:0038191 neuropilin binding(GO:0038191)
0.4 6.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.3 2.4 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.3 3.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.3 1.7 GO:0070492 oligosaccharide binding(GO:0070492)
0.3 4.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.3 6.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.3 5.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.3 23.3 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.3 5.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 3.1 GO:0005272 sodium channel activity(GO:0005272)
0.3 5.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.3 1.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3 3.3 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.3 2.2 GO:0001968 fibronectin binding(GO:0001968)
0.3 2.7 GO:0017046 peptide hormone binding(GO:0017046)
0.3 4.0 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 4.0 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.2 3.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.2 1.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.2 1.6 GO:0015026 coreceptor activity(GO:0015026)
0.2 1.3 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.2 1.5 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 1.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.2 7.3 GO:0008201 heparin binding(GO:0008201)
0.2 1.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 3.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 5.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.2 1.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2 4.9 GO:0051018 protein kinase A binding(GO:0051018)
0.2 3.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 2.8 GO:0030165 PDZ domain binding(GO:0030165)
0.2 5.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 5.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 11.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 3.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.7 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 72.3 GO:0005509 calcium ion binding(GO:0005509)
0.1 3.9 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.1 1.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 2.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 13.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 2.6 GO:0044325 ion channel binding(GO:0044325)
0.1 11.1 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.1 0.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 2.5 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 2.6 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.1 1.2 GO:0019843 rRNA binding(GO:0019843)
0.1 0.7 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 20.9 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 3.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 5.8 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.1 0.7 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 2.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 13.4 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 0.6 GO:0070700 BMP receptor binding(GO:0070700)
0.1 1.9 GO:0017124 SH3 domain binding(GO:0017124)
0.1 9.4 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 3.6 GO:0015293 symporter activity(GO:0015293)
0.0 1.1 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.4 GO:0016530 metallochaperone activity(GO:0016530) copper chaperone activity(GO:0016531)
0.0 43.8 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 1.3 GO:0015485 cholesterol binding(GO:0015485)
0.0 6.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 5.7 GO:0005198 structural molecule activity(GO:0005198)
0.0 11.3 GO:1990837 sequence-specific double-stranded DNA binding(GO:1990837)
0.0 0.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.4 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.6 GO:0045296 cadherin binding(GO:0045296)
0.0 0.9 GO:0005125 cytokine activity(GO:0005125)
0.0 0.5 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 2.7 GO:0038023 signaling receptor activity(GO:0038023)
0.0 0.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 4.7 GO:0005525 GTP binding(GO:0005525)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.7 14.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.5 8.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.4 5.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.4 13.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.3 5.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 21.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.2 19.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 1.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 2.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.2 3.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.2 1.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 3.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 1.9 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 2.1 PID RAS PATHWAY Regulation of Ras family activation
0.1 3.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 3.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 3.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 1.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 5.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 2.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 2.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 2.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.7 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 1.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.6 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.0 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
1.2 8.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
1.0 5.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.8 5.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.7 10.9 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.7 9.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.6 5.8 REACTOME BILE ACID AND BILE SALT METABOLISM Genes involved in Bile acid and bile salt metabolism
0.6 10.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.6 12.0 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.6 3.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.5 12.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.5 3.4 REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.5 2.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.5 3.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.4 12.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.3 3.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.3 3.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.3 2.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.3 7.8 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.3 2.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.3 3.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.2 5.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 8.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 0.6 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.2 1.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 3.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 3.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.2 2.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 2.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 7.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.9 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 1.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 6.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 2.2 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 5.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 2.1 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 11.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 1.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 2.1 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 2.5 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis