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Results for prrx1a+prrx1b

Z-value: 1.18

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Transcription factors associated with prrx1a+prrx1b

Gene Symbol Gene ID Gene Info
prrx1a
ENSDARG00000033971 paired related homeobox 1a
prrx1b
ENSDARG00000042027 paired related homeobox 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
prrx1adr10_dc_chr2_-_23516930_235169680.963.9e-09Click!
prrx1bdr10_dc_chr20_+_34608782_346088560.944.8e-08Click!

Activity profile of prrx1a+prrx1b motif

Sorted Z-values of prrx1a+prrx1b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of prrx1a+prrx1b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_+_9668755 4.13 ENSDART00000004604
si:dkey-153k10.9
si:dkey-153k10.9
chr2_+_27344633 3.68 ENSDART00000178275
cdh7
cadherin 7, type 2
chr16_-_31763183 3.50 ENSDART00000169109
rbp5
retinol binding protein 1a, cellular
chr20_-_22576513 3.15 ENSDART00000103510
pdgfra
platelet-derived growth factor receptor, alpha polypeptide
chr16_+_24069711 3.03 ENSDART00000142869
apoc2
apolipoprotein C-II
chr10_+_32160464 2.89 ENSDART00000099880
wnt11r
wingless-type MMTV integration site family, member 11, related
chr22_-_15567180 2.88 ENSDART00000123125
tpm4a
tropomyosin 4a
chr25_+_30699938 2.84 ENSDART00000036275
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr25_+_18866796 2.77 ENSDART00000017299
tdg.1
thymine DNA glycosylase, tandem duplicate 1
chr22_-_32553488 2.77 ENSDART00000104693
pcbp4
poly(rC) binding protein 4
chr1_+_44205158 2.77 ENSDART00000142820
wu:fc21g02
wu:fc21g02
chr12_-_954375 2.65 ENSDART00000054367
kdelr2b
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2b
chr3_+_28808901 2.58 ENSDART00000141904
ENSDART00000077221
lgals1l1
lectin, galactoside-binding, soluble, 1 (galectin 1)-like 1
chr13_+_24148599 2.47 ENSDART00000058629
acta1b
actin, alpha 1b, skeletal muscle
chr14_-_26238386 2.43 ENSDART00000105933
tgfbi
transforming growth factor, beta-induced
chr14_-_16791447 2.40 ENSDART00000158002
CR812832.1
ENSDARG00000103278
chr20_-_44598129 2.37 ENSDART00000012229
fkbp1b
FK506 binding protein 1b
chr3_-_32202533 2.34 ENSDART00000155757
si:dkey-16p21.8
si:dkey-16p21.8
chr13_+_23065500 2.34 ENSDART00000158370
sorbs1
sorbin and SH3 domain containing 1
chr11_-_44724371 2.33 ENSDART00000166501
cant1b
calcium activated nucleotidase 1b
chr7_+_6814828 2.32 ENSDART00000001649
actn3b
actinin alpha 3b
chr7_+_26357875 2.20 ENSDART00000101044
hsbp1a
heat shock factor binding protein 1a
chr25_+_4918339 2.15 ENSDART00000153980
parvb
parvin, beta
chr6_+_23787804 2.13 ENSDART00000163188
znf648
zinc finger protein 648
chr6_+_6767424 2.13 ENSDART00000065551
ENSDART00000151393
zak
sterile alpha motif and leucine zipper containing kinase AZK
chr20_-_21031504 2.12 ENSDART00000152726
btbd6b
BTB (POZ) domain containing 6b
chr24_-_23797468 2.11 ENSDART00000080810
arxa
aristaless related homeobox a
chr10_+_7125001 2.09 ENSDART00000157987
psd3l
pleckstrin and Sec7 domain containing 3, like
chr8_-_9081109 2.07 ENSDART00000176850
slc6a8
solute carrier family 6 (neurotransmitter transporter), member 8
chr9_-_34491458 1.97 ENSDART00000049805
ildr2
immunoglobulin-like domain containing receptor 2
chr12_+_42281025 1.94 ENSDART00000167324
ebf3a
early B-cell factor 3a
chr2_+_30932612 1.93 ENSDART00000132450
ENSDART00000137012
myom1a
myomesin 1a (skelemin)
chr24_-_1155215 1.88 ENSDART00000177356
itgb1a
integrin, beta 1a
chr14_-_20760787 1.85

chr6_+_8895437 1.84 ENSDART00000162588
rgn
regucalcin
chr11_+_21749658 1.83 ENSDART00000161485
foxp4
forkhead box P4
chr3_+_56970554 1.81 ENSDART00000162930
bahcc1a
BAH domain and coiled-coil containing 1a
chr1_+_13779755 1.81

chr1_-_40208544 1.80 ENSDART00000027463
hmx4
H6 family homeobox 4
chr1_+_14540517 1.76

chr20_+_34417665 1.74 ENSDART00000153207
ivns1abpa
influenza virus NS1A binding protein a
chr5_+_26804344 1.73 ENSDART00000121886
ENSDART00000005025
hdr
hematopoietic death receptor
chr7_-_30096283 1.71 ENSDART00000075519
aldh1a2
aldehyde dehydrogenase 1 family, member A2
chr1_-_40208469 1.69 ENSDART00000027463
hmx4
H6 family homeobox 4
chr24_-_21778717 1.68 ENSDART00000131944
tagln3b
transgelin 3b
chr8_+_2428689 1.67 ENSDART00000081325
dynll1
dynein, light chain, LC8-type 1
chr2_+_38057483 1.66 ENSDART00000159951
casq1a
calsequestrin 1a
chr21_+_7844259 1.65 ENSDART00000027268
otpa
orthopedia homeobox a
chr2_+_56339323 1.64 ENSDART00000123392
rab11bb
RAB11B, member RAS oncogene family, b
chr6_-_23455346 1.61 ENSDART00000157527
ENSDART00000168882
ENSDART00000171384
ntn1a
netrin 1a
chr8_+_3026357 1.61 ENSDART00000148020
ENSDART00000157599
lhx2b
LIM homeobox 2b
chr13_+_33378267 1.60 ENSDART00000025007
jag2a
jagged 2a
chr8_-_14054145 1.59 ENSDART00000137857
si:ch211-229n2.7
si:ch211-229n2.7
chr19_-_22182031 1.56 ENSDART00000104279
znf516
zinc finger protein 516
chr11_+_8558222 1.56 ENSDART00000169141
ENSDART00000126523
tbl1xr1a
transducin (beta)-like 1 X-linked receptor 1a
chr25_+_19992389 1.56 ENSDART00000143441
tnni4b.2
troponin I4b, tandem duplicate 2
chr21_-_27845076 1.55 ENSDART00000132583
nrxn2a
neurexin 2a
chr4_-_12862869 1.54 ENSDART00000080536
hmga2
high mobility group AT-hook 2
chr1_+_16983775 1.51 ENSDART00000030665
slc25a4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr6_-_12953515 1.50 ENSDART00000150036
ENSDART00000149940
adam23a
ADAM metallopeptidase domain 23a
chr16_+_737615 1.49 ENSDART00000161774
irx1a
iroquois homeobox 1a
chr2_-_20490037 1.48 ENSDART00000160388
FQ377605.1
ENSDARG00000101927
chr5_+_48031920 1.48 ENSDART00000008043
ENSDART00000171438
adgrv1
adhesion G protein-coupled receptor V1
chr7_+_19895162 1.48 ENSDART00000011398
si:ch73-335l21.1
si:ch73-335l21.1
chr11_-_37158131 1.47 ENSDART00000160911
erc2
ELKS/RAB6-interacting/CAST family member 2
chr1_+_16681778 1.46

chr10_-_26782374 1.45 ENSDART00000162710
fgf13b
fibroblast growth factor 13b
chr14_-_24113324 1.43 ENSDART00000125923
cxcl14
chemokine (C-X-C motif) ligand 14
chr5_-_64348528 1.43 ENSDART00000158856
anxa1b
annexin A1b
chr13_-_23536022 1.41

chr3_+_31542311 1.41

chr13_-_31491759 1.40 ENSDART00000057432
six1a
SIX homeobox 1a
chr24_+_41790437 1.39 ENSDART00000159135
ENSDART00000158456
ENSDART00000160069
lama1
laminin, alpha 1
chr23_+_11350727 1.39

chr16_+_14817718 1.38 ENSDART00000027982
col14a1a
collagen, type XIV, alpha 1a
chr12_+_18559530 1.37 ENSDART00000152948
rgs9b
regulator of G protein signaling 9b
chr14_+_6122948 1.37 ENSDART00000149783
ENSDART00000148461
abca1b
ATP-binding cassette, sub-family A (ABC1), member 1B
chr17_+_38528709 1.36 ENSDART00000123298
stard9
StAR-related lipid transfer (START) domain containing 9
chr19_-_3299610 1.34 ENSDART00000105168
si:ch211-133n4.4
si:ch211-133n4.4
chr7_-_26165200 1.34 ENSDART00000123395
her8a
hairy-related 8a
chr1_+_18118995 1.34 ENSDART00000078610
slc25a51a
solute carrier family 25, member 51a
chr2_-_9691594 1.33 ENSDART00000146715
st6galnac3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr18_+_23891068 1.32 ENSDART00000146490
BX569787.1
ENSDARG00000092402
chr14_+_6834563 1.32 ENSDART00000170994
ENSDART00000129898
ctsf
cathepsin F
chr24_+_30343717 1.31 ENSDART00000162377
FP085414.1
ENSDARG00000100270
chr15_+_35184996 1.30 ENSDART00000086954
ENSDART00000161594
sesn3
sestrin 3
chr12_+_15624640 1.29 ENSDART00000079803
nmt1b
N-myristoyltransferase 1b
chr11_+_37639045 1.28 ENSDART00000111157
si:ch211-112f3.4
si:ch211-112f3.4
chr25_+_558191 1.27 ENSDART00000126863
ENSDART00000166012
nell2a
neural EGFL like 2a
chr5_-_31301280 1.27 ENSDART00000141446
coro1cb
coronin, actin binding protein, 1Cb
chr19_+_4208233 1.27 ENSDART00000172524
TRAPPC9
trafficking protein particle complex 9
chr2_+_33399405 1.26 ENSDART00000137207
slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr19_+_2754903 1.25 ENSDART00000160533
tomm7
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr1_-_44348236 1.24 ENSDART00000023336
rps6
ribosomal protein S6
chr5_-_19357961 1.24 ENSDART00000088904
ENSDART00000163701
gltpa
glycolipid transfer protein a
chr16_-_42968807 1.22 ENSDART00000154757
txnipb
thioredoxin interacting protein b
chr20_-_54192057 1.22 ENSDART00000023550
hsp90aa1.2
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2
chr4_-_16356071 1.21 ENSDART00000079521
kera
keratocan
chr4_+_5826813 1.21 ENSDART00000055414
pex26
peroxisomal biogenesis factor 26
chr5_-_56984800 1.21 ENSDART00000074290
mia
melanoma inhibitory activity
chr6_-_343209 1.21

chr15_+_43714699 1.20 ENSDART00000168191
ENSDARG00000102235
ENSDARG00000102235
chr10_+_9575 1.20

KN150108v1_-_8893 1.20 ENSDART00000167033
ENSDARG00000100513
ENSDARG00000100513
chr7_+_13753344 1.20

chr2_-_49114158 1.20

chr1_-_674449 1.20 ENSDART00000160564
cyyr1
cysteine/tyrosine-rich 1
chr20_-_34389652 1.20 ENSDART00000144705
ENSDART00000020389
hmcn1
hemicentin 1
chr7_-_72278552 1.19 ENSDART00000168532
HECTD4
HECT domain E3 ubiquitin protein ligase 4
chr21_+_13764828 1.19 ENSDART00000171306
stxbp1a
syntaxin binding protein 1a
chr11_+_6118322 1.16 ENSDART00000165031
nr2f6b
nuclear receptor subfamily 2, group F, member 6b
chr19_+_32183937 1.16 ENSDART00000147474
stmn2b
stathmin 2b
chr19_+_17461581 1.16 ENSDART00000159838
lye
lymphocyte antigen-6, epidermis
chr7_+_28896401 1.14 ENSDART00000076345
slc38a8b
solute carrier family 38, member 8b
chr21_+_10775209 1.13

chr24_+_9335428 1.13 ENSDART00000132688
si:ch211-285f17.1
si:ch211-285f17.1
chr17_+_37306052 1.13 ENSDART00000134000
tmem62
transmembrane protein 62
chr19_-_28546417 1.13 ENSDART00000130922
ENSDART00000079114
irx1b
iroquois homeobox 1b
chr23_+_26806694 1.12 ENSDART00000035080
zgc:158263
zgc:158263
chr15_-_19789174 1.11 ENSDART00000152345
ENSDART00000047643
ENSDART00000163435
sytl2b
synaptotagmin-like 2b
chr9_-_56292487 1.11 ENSDART00000151720
si:ch211-39i22.1
si:ch211-39i22.1
chr16_-_21334269 1.11 ENSDART00000145837
si:dkey-271j15.3
si:dkey-271j15.3
chr12_+_17382681 1.11 ENSDART00000020628
cyth3a
cytohesin 3a
chr7_-_34656224 1.10 ENSDART00000073397
nfatc3a
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3a
chr14_-_16762869 1.10 ENSDART00000163766
phox2bb
paired-like homeobox 2bb
chr19_-_7576069 1.07 ENSDART00000148836
rfx5
regulatory factor X, 5
chr14_-_47083485 1.07 ENSDART00000172512
elf2a
E74-like factor 2a (ets domain transcription factor)
chr14_-_16762762 1.06 ENSDART00000106333
phox2bb
paired-like homeobox 2bb
chr4_-_376986 1.06 ENSDART00000067482
ENSDART00000160718
dynlt1
dynein, light chain, Tctex-type 1
chr5_+_50432868 1.06 ENSDART00000097466
fam169aa
family with sequence similarity 169, member Aa
chr23_+_25224499 1.06

chr9_+_34832049 1.05 ENSDART00000100735
ENSDART00000133996
shox
short stature homeobox
chr23_+_19018062 1.05 ENSDART00000104487
cox4i2
cytochrome c oxidase subunit IV isoform 2
chr21_-_44109455 1.03 ENSDART00000044599
oatx
organic anion transporter X
chr3_+_12287067 1.02 ENSDART00000158060
vasnb
vasorin b
chr14_-_24304373 1.02

chr8_+_15216833 1.01 ENSDART00000141185
slc5a9
solute carrier family 5 (sodium/sugar cotransporter), member 9
chr13_+_30097568 1.01 ENSDART00000134691
rps24
ribosomal protein S24
chr10_+_7296895 1.01 ENSDART00000161506
fut10
fucosyltransferase 10
chr6_-_40886902 0.99 ENSDART00000017968
ENSDART00000154100
sirt4
sirtuin 4
chr3_+_32234028 0.98 ENSDART00000155967
ap2a1
adaptor-related protein complex 2, alpha 1 subunit
chr18_+_23891152 0.98 ENSDART00000146490
BX569787.1
ENSDARG00000092402
chr16_-_13733759 0.97 ENSDART00000164344
si:dkeyp-69b9.6
si:dkeyp-69b9.6
chr20_+_23599157 0.97 ENSDART00000149922
palld
palladin, cytoskeletal associated protein
chr1_-_46015367 0.97 ENSDART00000074519
kpna3
karyopherin alpha 3 (importin alpha 4)
chr8_+_3026415 0.96 ENSDART00000136250
lhx2b
LIM homeobox 2b
chr23_+_5899604 0.96

chr25_-_21618526 0.95 ENSDART00000152011
DOCK4 (1 of many)
dedicator of cytokinesis 4
chr25_-_13631707 0.95 ENSDART00000169865
lcat
lecithin-cholesterol acyltransferase
chr2_+_49683715 0.94 ENSDART00000122742
ENSDART00000160783
rorcb
RAR-related orphan receptor C b
chr20_-_9474672 0.93 ENSDART00000152674
ENSDARG00000033201
ENSDARG00000033201
chr20_-_27193158 0.92 ENSDART00000062096
si:dkeyp-55f12.3
si:dkeyp-55f12.3
chr25_+_34745872 0.90 ENSDART00000003494
slc17a6a
solute carrier family 17 (vesicular glutamate transporter), member 6a
chr11_-_42263721 0.90 ENSDART00000130573
atp6ap1la
ATPase, H+ transporting, lysosomal accessory protein 1-like a
chr21_-_10354049 0.89 ENSDART00000159958
hcn1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr14_-_33704021 0.88 ENSDART00000149396
ENSDART00000123607
cyfip2
cytoplasmic FMR1 interacting protein 2
chr25_+_28717079 0.88 ENSDART00000162854
pkmb
pyruvate kinase, muscle, b
chr24_-_14447773 0.88

chr20_+_31384580 0.87 ENSDART00000007688
slc22a16
solute carrier family 22 (organic cation/carnitine transporter), member 16
chr4_+_6024067 0.87

chr6_-_8075384 0.87 ENSDART00000129674
slc44a2
solute carrier family 44 (choline transporter), member 2
chr11_+_30569525 0.87

chr8_+_44765658 0.87 ENSDART00000025875
ENSDARG00000006901
ENSDARG00000006901
chr16_-_2972770 0.86 ENSDART00000082522
abcd2
ATP-binding cassette, sub-family D (ALD), member 2
chr13_-_40190349 0.86 ENSDART00000009343
pyroxd2
pyridine nucleotide-disulphide oxidoreductase domain 2
chr4_+_8667698 0.86

chr24_-_38496534 0.86 ENSDART00000140739
lrrc4bb
leucine rich repeat containing 4Bb
chr3_+_28822408 0.86 ENSDART00000133528
lgals2a
lectin, galactoside-binding, soluble, 2a
chr13_-_29290894 0.86 ENSDART00000150228
chata
choline O-acetyltransferase a
chr13_+_30743690 0.85 ENSDART00000134809
ercc6
excision repair cross-complementation group 6
chr9_-_27838603 0.85

chr1_-_50215233 0.85 ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr5_+_64411412 0.85 ENSDART00000158484
BX001023.2
ENSDARG00000101163
chr23_-_12410797 0.84 ENSDART00000133956
phactr3a
phosphatase and actin regulator 3a
chr6_+_43429115 0.84 ENSDART00000056457
mitfa
microphthalmia-associated transcription factor a
chr6_-_3413472 0.84 ENSDART00000026693
dmbx1b
diencephalon/mesencephalon homeobox 1b
chr24_-_39997875 0.83 ENSDART00000143476
slc12a7b
solute carrier family 12 (potassium/chloride transporter), member 7b
chr6_+_16341787 0.83 ENSDART00000114667
zgc:161969
zgc:161969
chr4_-_28384562 0.83 ENSDART00000056132
tprkb
Tp53rk binding protein
chr8_-_7548976 0.83 ENSDART00000132536
hcfc1b
host cell factor C1b
chr22_-_864745 0.83 ENSDART00000035514
cept1b
choline/ethanolamine phosphotransferase 1b
chr24_+_30343687 0.82 ENSDART00000162377
FP085414.1
ENSDARG00000100270
chr10_-_28949067 0.81 ENSDART00000030138
alcama
activated leukocyte cell adhesion molecule a
chr1_+_45843326 0.81

chr24_+_19374200 0.80 ENSDART00000056081
ENSDART00000027022
sulf1
sulfatase 1
chr2_+_29729161 0.80 ENSDART00000141666
AL845362.1
ENSDARG00000093205
chr14_-_24113237 0.80 ENSDART00000125923
cxcl14
chemokine (C-X-C motif) ligand 14
chr3_-_12818954 0.79 ENSDART00000158747
ENSDART00000158815
pdgfab
platelet-derived growth factor alpha polypeptide b
chr23_-_18203680 0.78 ENSDART00000016976
nucks1b
nuclear casein kinase and cyclin-dependent kinase substrate 1b
chr9_-_51975919 0.78 ENSDART00000006612
tbr1b
T-box, brain, 1b
chr6_+_40664212 0.78 ENSDART00000103842
eno1b
enolase 1b, (alpha)
chr16_-_16682692 0.77 ENSDART00000059841
si:ch211-257p13.3
si:ch211-257p13.3
chr16_-_31763281 0.77 ENSDART00000169109
rbp5
retinol binding protein 1a, cellular
chr7_-_34656337 0.77 ENSDART00000073397
nfatc3a
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3a
chr3_-_30027552 0.77 ENSDART00000103502
si:ch211-152f23.5
si:ch211-152f23.5
chr15_+_42329269 0.76 ENSDART00000099234
ENSDART00000152731
scaf4b
SR-related CTD-associated factor 4b
chr21_+_13764917 0.76 ENSDART00000015629
stxbp1a
syntaxin binding protein 1a
chr20_-_43878454 0.75 ENSDART00000100610
ENSDART00000100608
ENSDART00000148809
matn3a
matrilin 3a
chr22_+_31866783 0.75 ENSDART00000159825
dock3
dedicator of cytokinesis 3
chr24_-_16922912 0.75 ENSDART00000111237
armc3
armadillo repeat containing 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.7 2.2 GO:0061549 sympathetic ganglion development(GO:0061549)
0.7 2.8 GO:0033119 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.6 2.5 GO:0003322 pancreatic A cell development(GO:0003322)
0.6 2.3 GO:0035908 ventral aorta development(GO:0035908) pharyngeal arch artery morphogenesis(GO:0061626)
0.6 1.7 GO:0061114 branching involved in pancreas morphogenesis(GO:0061114) pancreatic bud formation(GO:0061130) pancreas field specification(GO:0061131)
0.6 1.7 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.5 1.6 GO:0070292 N-acylphosphatidylethanolamine metabolic process(GO:0070292)
0.5 2.6 GO:0071632 optomotor response(GO:0071632)
0.5 1.5 GO:0030815 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclic nucleotide metabolic process(GO:0030800) negative regulation of cyclic nucleotide biosynthetic process(GO:0030803) negative regulation of nucleotide biosynthetic process(GO:0030809) negative regulation of cAMP metabolic process(GO:0030815) negative regulation of cAMP biosynthetic process(GO:0030818) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350) negative regulation of purine nucleotide biosynthetic process(GO:1900372)
0.5 1.4 GO:0010519 positive regulation of adaptive immune response(GO:0002821) positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002824) negative regulation of phospholipase activity(GO:0010519) positive regulation of vesicle fusion(GO:0031340) type 2 immune response(GO:0042092) regulation of fatty acid biosynthetic process(GO:0042304) T-helper 2 cell differentiation(GO:0045064) leukocyte apoptotic process(GO:0071887) regulation of leukocyte apoptotic process(GO:2000106)
0.5 2.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.5 1.4 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.5 1.8 GO:0042364 L-ascorbic acid metabolic process(GO:0019852) water-soluble vitamin biosynthetic process(GO:0042364) regulation of calcium-mediated signaling(GO:0050848)
0.4 2.7 GO:0006621 protein retention in ER lumen(GO:0006621)
0.4 1.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.4 1.2 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.4 1.5 GO:1990544 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.4 3.2 GO:0003315 heart rudiment formation(GO:0003315)
0.3 1.7 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.3 1.0 GO:0015695 organic cation transport(GO:0015695)
0.3 1.3 GO:0018377 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.3 1.3 GO:0099565 chemical synaptic transmission, postsynaptic(GO:0099565)
0.3 0.6 GO:0055091 phospholipid homeostasis(GO:0055091)
0.3 1.2 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.3 1.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.3 2.8 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.3 0.8 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.3 3.5 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.2 1.2 GO:0046677 response to antibiotic(GO:0046677)
0.2 0.7 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.2 0.9 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.2 3.0 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.2 1.4 GO:0014856 skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857)
0.2 2.6 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.2 0.8 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.2 0.6 GO:0042554 superoxide anion generation(GO:0042554)
0.2 1.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 4.4 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 0.9 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 0.7 GO:0010269 response to selenium ion(GO:0010269)
0.2 0.9 GO:0090303 positive regulation of wound healing(GO:0090303)
0.2 1.3 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.2 3.2 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.9 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 1.0 GO:0036065 fucosylation(GO:0036065)
0.1 2.6 GO:0071711 basement membrane organization(GO:0071711)
0.1 0.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 1.7 GO:0021767 mammillary body development(GO:0021767)
0.1 0.5 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.1 0.6 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.9 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 2.9 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 2.8 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.1 1.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.6 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.1 1.1 GO:0006956 complement activation(GO:0006956)
0.1 0.9 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.1 1.9 GO:1903672 positive regulation of sprouting angiogenesis(GO:1903672)
0.1 0.3 GO:0043476 pigment accumulation(GO:0043476) Golgi vesicle docking(GO:0048211)
0.1 0.7 GO:0044458 motile cilium assembly(GO:0044458)
0.1 0.9 GO:0001964 startle response(GO:0001964)
0.1 0.8 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
0.1 0.4 GO:0098900 regulation of action potential(GO:0098900)
0.1 0.3 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.1 2.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.8 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
0.1 1.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.5 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.1 5.6 GO:0048747 muscle fiber development(GO:0048747)
0.1 2.0 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 1.1 GO:0006825 copper ion transport(GO:0006825)
0.1 0.8 GO:0061074 regulation of neural retina development(GO:0061074)
0.1 0.8 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 2.2 GO:0060326 cell chemotaxis(GO:0060326)
0.1 1.0 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.4 GO:0006706 steroid catabolic process(GO:0006706)
0.1 0.8 GO:0002250 adaptive immune response(GO:0002250)
0.0 1.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.4 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.6 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.3 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.0 1.5 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.9 GO:0015696 ammonium transport(GO:0015696)
0.0 0.4 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.0 0.4 GO:1902110 positive regulation of mitochondrial membrane permeability(GO:0035794) mitochondrial outer membrane permeabilization(GO:0097345) positive regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902110) mitochondrial outer membrane permeabilization involved in programmed cell death(GO:1902686)
0.0 0.6 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 1.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 1.2 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.2 GO:0099638 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 1.1 GO:0030282 bone mineralization(GO:0030282)
0.0 0.3 GO:0033700 phospholipid efflux(GO:0033700)
0.0 1.7 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.7 GO:2001236 regulation of extrinsic apoptotic signaling pathway(GO:2001236)
0.0 0.8 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 1.5 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 0.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.8 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.2 GO:0002090 regulation of receptor internalization(GO:0002090) positive regulation of receptor-mediated endocytosis(GO:0048260)
0.0 1.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 1.9 GO:0006936 muscle contraction(GO:0006936)
0.0 0.8 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.1 GO:0016203 muscle attachment(GO:0016203)
0.0 0.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0046958 learning(GO:0007612) nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.6 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.3 GO:0001649 osteoblast differentiation(GO:0001649)
0.0 0.4 GO:0009648 photoperiodism(GO:0009648)
0.0 0.9 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 0.5 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 4.8 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.1 GO:0010883 regulation of lipid storage(GO:0010883)
0.0 1.1 GO:0007601 visual perception(GO:0007601)
0.0 1.1 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.1 GO:0006672 ceramide metabolic process(GO:0006672)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.4 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 1.6 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.3 GO:0050708 regulation of protein secretion(GO:0050708)
0.0 2.0 GO:0031016 pancreas development(GO:0031016)
0.0 0.6 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.0 0.5 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.3 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 0.0 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.0 0.3 GO:0001843 neural tube closure(GO:0001843)
0.0 1.2 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.3 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.3 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.2 GO:0048278 vesicle docking(GO:0048278)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:0042627 chylomicron(GO:0042627)
0.3 1.7 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.3 1.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.3 1.5 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.2 1.7 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.2 3.2 GO:0005869 dynactin complex(GO:0005869)
0.2 4.4 GO:0005861 troponin complex(GO:0005861)
0.2 0.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 1.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 1.9 GO:0031430 M band(GO:0031430)
0.2 4.0 GO:0032587 ruffle membrane(GO:0032587)
0.2 1.4 GO:0005614 interstitial matrix(GO:0005614)
0.2 2.7 GO:0005801 cis-Golgi network(GO:0005801)
0.2 1.3 GO:0061700 GATOR2 complex(GO:0061700)
0.2 1.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 1.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.2 GO:0043209 myelin sheath(GO:0043209)
0.1 1.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.9 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.7 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 0.6 GO:0030897 HOPS complex(GO:0030897)
0.1 0.5 GO:0044304 main axon(GO:0044304)
0.1 1.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.9 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.5 GO:0001650 fibrillar center(GO:0001650)
0.1 3.8 GO:0005604 basement membrane(GO:0005604)
0.1 0.9 GO:0031209 SCAR complex(GO:0031209)
0.1 2.6 GO:0030426 growth cone(GO:0030426)
0.1 0.3 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 2.9 GO:0005884 actin filament(GO:0005884)
0.0 0.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.9 GO:0005871 kinesin complex(GO:0005871)
0.0 1.9 GO:0030141 secretory granule(GO:0030141)
0.0 2.1 GO:0030018 Z disc(GO:0030018)
0.0 2.2 GO:0005795 Golgi stack(GO:0005795)
0.0 0.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.1 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 1.4 GO:0055037 recycling endosome(GO:0055037)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 9.3 GO:0005615 extracellular space(GO:0005615)
0.0 0.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0030175 filopodium(GO:0030175)
0.0 1.2 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.5 GO:0031201 SNARE complex(GO:0031201)
0.0 0.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.4 GO:0016936 galactoside binding(GO:0016936)
0.7 4.3 GO:0016918 retinal binding(GO:0016918)
0.6 1.9 GO:0019960 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.4 1.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.4 2.8 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.4 1.5 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.4 1.1 GO:0001729 ceramide kinase activity(GO:0001729)
0.4 1.5 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.3 1.0 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.3 1.3 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.3 0.9 GO:0004743 pyruvate kinase activity(GO:0004743)
0.3 0.8 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.2 2.2 GO:0008009 chemokine activity(GO:0008009) chemokine receptor binding(GO:0042379)
0.2 0.9 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.2 1.0 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 0.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 1.7 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.2 1.4 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.2 0.5 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.2 0.9 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.2 1.3 GO:0070728 leucine binding(GO:0070728)
0.2 2.3 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 1.0 GO:0015149 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.1 1.6 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 1.7 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 1.5 GO:0005158 insulin receptor binding(GO:0005158)
0.1 2.2 GO:0005518 collagen binding(GO:0005518)
0.1 1.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.9 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 1.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.7 GO:0052659 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.1 1.1 GO:0016531 copper chaperone activity(GO:0016531)
0.1 1.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 3.6 GO:0005048 signal sequence binding(GO:0005048)
0.1 1.4 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.6 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 1.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.6 GO:0005112 Notch binding(GO:0005112)
0.1 1.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.8 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 0.9 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.9 GO:0005272 sodium channel activity(GO:0005272) cAMP binding(GO:0030552)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 1.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.9 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 1.0 GO:0070403 NAD+ binding(GO:0070403)
0.1 1.0 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.3 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.9 GO:0005324 long-chain fatty acid transporter activity(GO:0005324) fatty acid transporter activity(GO:0015245)
0.1 0.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 2.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.5 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.3 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 3.2 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.9 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 1.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 1.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.7 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.6 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 4.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.8 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 2.1 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.6 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.5 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.0 1.5 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 1.4 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 10.0 GO:0003779 actin binding(GO:0003779)
0.0 1.5 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.4 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.0 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.7 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 0.6 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.3 GO:0016208 AMP binding(GO:0016208)
0.0 0.4 GO:0017124 SH3 domain binding(GO:0017124)
0.0 5.3 GO:0005509 calcium ion binding(GO:0005509)
0.0 14.8 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.3 GO:0019003 GDP binding(GO:0019003)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 2.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 1.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 3.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 1.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 1.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 1.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 0.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.3 2.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.3 1.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 0.9 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.2 1.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 1.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 2.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 3.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 0.9 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 2.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.5 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.4 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.9 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 1.0 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.7 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.9 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 1.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production