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Results for raraa+rarab

Z-value: 0.65

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Transcription factors associated with raraa+rarab

Gene Symbol Gene ID Gene Info
rarab
ENSDARG00000034893 retinoic acid receptor, alpha b
raraa
ENSDARG00000056783 retinoic acid receptor, alpha a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
raraadr10_dc_chr12_+_11042472_110425070.918.8e-07Click!
rarabdr10_dc_chr3_-_33127793_33127962-0.155.7e-01Click!

Activity profile of raraa+rarab motif

Sorted Z-values of raraa+rarab motif

Network of associatons between targets according to the STRING database.

First level regulatory network of raraa+rarab

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr21_+_28408329 3.06 ENSDART00000077871
pygma
phosphorylase, glycogen, muscle A
chr6_-_39315024 1.82 ENSDART00000012644
krt4
keratin 4
chr2_+_53253623 1.69 ENSDART00000121980
creb3l3b
cAMP responsive element binding protein 3-like 3b
chr13_+_24703802 1.48 ENSDART00000101274
zgc:153981
zgc:153981
chr5_+_64175669 1.42 ENSDART00000050863
zgc:101858
zgc:101858
chr17_+_53224434 1.38 ENSDART00000166517
asb2b
ankyrin repeat and SOCS box containing 2b
chr8_-_28323246 1.22 ENSDART00000005583
kdm5bb
lysine (K)-specific demethylase 5Bb
chr22_+_30060679 1.01 ENSDART00000142529
si:dkey-286j15.1
si:dkey-286j15.1
chr23_+_25378921 0.95 ENSDART00000143291
RPL41
ribosomal protein L41
chr5_-_3562233 0.90 ENSDART00000143250
si:ch1073-189o9.1
si:ch1073-189o9.1
chr14_+_36156947 0.89

chr17_+_14878846 0.77 ENSDART00000010507
ENSDART00000131052
ptger2a
prostaglandin E receptor 2a (subtype EP2)
chr14_+_151136 0.65 ENSDART00000165766
mcm7
minichromosome maintenance complex component 7
chr19_+_20189224 0.65 ENSDART00000163611
hoxa4a
homeobox A4a
chr14_-_51837257 0.64 ENSDART00000170107
ppp2r2ba
protein phosphatase 2, regulatory subunit B, beta a
chr15_+_1238615 0.64 ENSDART00000167760
ENSDART00000163827
mfsd1
major facilitator superfamily domain containing 1
chr24_-_36840203 0.62 ENSDART00000135142
si:ch73-334d15.1
si:ch73-334d15.1
chr8_+_37136126 0.60 ENSDART00000098636
csf1b
colony stimulating factor 1b (macrophage)
chr8_+_54003190 0.57

chr5_+_64175494 0.57 ENSDART00000050863
zgc:101858
zgc:101858
chr4_+_1680973 0.56 ENSDART00000149826
ENSDART00000166437
ENSDART00000031135
ENSDART00000172300
ENSDART00000067446
slc38a4
solute carrier family 38, member 4
chr20_-_49965171 0.53

chr18_-_36085063 0.42 ENSDART00000059352
ENSDART00000145177
exosc5
exosome component 5
chr24_+_21828704 0.39 ENSDART00000042495
sat1b
spermidine/spermine N1-acetyltransferase 1b
chr12_-_3742020 0.36 ENSDART00000092983
ENSDARG00000063555
ENSDARG00000063555
chr6_-_12035327 0.26

chr20_+_25727285 0.23 ENSDART00000143883
ppat
phosphoribosyl pyrophosphate amidotransferase
chr8_-_337744 0.22

chr11_-_27970634 0.22

chr2_+_58654570 0.21 ENSDART00000164102
ENSDART00000158777
cirbpa
cold inducible RNA binding protein a
chr16_+_7325399 0.17 ENSDART00000081477
sri
sorcin
chr10_+_6494926 0.14 ENSDART00000164770
reep5
receptor accessory protein 5
chr19_+_20189194 0.12 ENSDART00000163611
hoxa4a
homeobox A4a
chr13_+_24703728 0.07 ENSDART00000101274
zgc:153981
zgc:153981
chr12_+_26972001 0.07

chr12_+_26971596 0.05

chr22_-_817086 0.04 ENSDART00000105873
cry4
cryptochrome circadian clock 4
chr19_-_29196131 0.02 ENSDART00000155766
ENSDART00000151806
BX957317.2
ENSDARG00000096312

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.1 GO:0044247 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.2 0.8 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.1 0.4 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 1.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.7 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 1.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.4 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.2 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
0.0 0.6 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 GO:0045095 keratin filament(GO:0045095)
0.0 0.7 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0000177 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.3 0.8 GO:0004953 icosanoid receptor activity(GO:0004953)
0.2 1.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.2 0.7 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.1 0.4 GO:0019808 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.1 1.7 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.2 GO:0004044 amidophosphoribosyltransferase activity(GO:0004044)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 1.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation