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Results for rargb_pparab

Z-value: 1.60

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Transcription factors associated with rargb_pparab

Gene Symbol Gene ID Gene Info
ENSDARG00000054003 retinoic acid receptor, gamma b
ENSDARG00000054323 peroxisome proliferator-activated receptor alpha b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pparabdr10_dc_chr25_+_2107536_21075800.621.0e-02Click!

Activity profile of rargb_pparab motif

Sorted Z-values of rargb_pparab motif

Network of associatons between targets according to the STRING database.

First level regulatory network of rargb_pparab

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr23_+_44817648 4.41 ENSDART00000143688
discs, large homolog 4b (Drosophila)
chr11_+_11217547 4.38 ENSDART00000087105
myomesin 2a
chr5_+_40722565 4.28 ENSDART00000097546
AT rich interactive domain 3C (BRIGHT-like)
chr3_+_33168814 4.24 ENSDART00000114023
heat shock protein, alpha-crystallin-related, 9
chr13_-_39033893 4.18 ENSDART00000045434
collagen, type IX, alpha 1b
chr22_-_17570306 4.10 ENSDART00000139361
glutathione peroxidase 4a
chr18_+_62936 4.02 ENSDART00000052638
solute carrier family 27 (fatty acid transporter), member 2a
chr2_+_42342148 3.91 ENSDART00000144716
caveolae associated protein 4a
chr22_+_33177432 3.89 ENSDART00000126885
dystroglycan 1
chr13_-_37001997 3.88 ENSDART00000135510
spectrin repeat containing, nuclear envelope 2b
chr16_+_29716279 3.84 ENSDART00000137153
tropomodulin 4 (muscle)
chr2_-_47578695 3.81 ENSDART00000014350
ENSDART00000038828
paired box 3a
chr12_-_5085227 3.76 ENSDART00000160729
retinol binding protein 4, plasma
chr3_-_48865474 3.70 ENSDART00000133036
ELAV like neuron-specific RNA binding protein 3
chr18_-_39491932 3.70 ENSDART00000122930
secretogranin III
chr15_-_29454583 3.68 ENSDART00000145976
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr20_+_2255204 3.65 ENSDART00000137579
si:ch73-18b11.2
chr13_+_1595986 3.63

chr3_+_39425125 3.59 ENSDART00000146867
aldolase a, fructose-bisphosphate, a
chr3_+_23587156 3.57

chr12_+_27032862 3.52

chr10_-_44180588 3.49 ENSDART00000145404
crystallin, beta B1
chr17_+_16067769 3.41 ENSDART00000155292
si:ch73-204p21.2
chr7_+_25758469 3.23 ENSDART00000101126
arachidonate 12-lipoxygenase
chr24_-_12794057 3.16 ENSDART00000024084
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr4_-_16461748 3.16 ENSDART00000128835
wu:fc23c09
chr9_+_42112576 3.16 ENSDART00000130434
ENSDART00000007058
collagen type XVIII alpha 1 chain a
chr13_-_37144297 3.15

chr17_+_8874210 3.08

chr5_-_46382728 3.07

chr14_-_48951428 3.03 ENSDART00000157785
Rap guanine nucleotide exchange factor (GEF) 2
chr25_+_4490129 3.01

chr2_-_43110857 2.98 ENSDART00000098303
otoconin 90
chr15_+_24708696 2.96 ENSDART00000043292
smoothelin, like
chr4_-_1346961 2.85 ENSDART00000164623
pleiotrophin
chr3_-_18426055 2.84 ENSDART00000122968
aquaporin 8b
chr19_-_7069920 2.80 ENSDART00000145741
zinc finger protein 384 like
chr6_-_13654186 2.77 ENSDART00000150102
ENSDART00000041269
crystallin, beta A2a
chr18_+_45893199 2.76 ENSDART00000158246
dishevelled segment polarity protein 3b
chr6_+_3549861 2.69 ENSDART00000170781
phosphatase, orphan 2
chr2_+_45228446 2.69 ENSDART00000123966
cholinergic receptor, nicotinic, gamma
chr14_+_14272033 2.65 ENSDART00000167483
proteolipid protein 1a
chr9_-_41982635 2.64 ENSDART00000144573
obscurin-like 1b
chr24_-_21778717 2.64 ENSDART00000131944
transgelin 3b
chr6_-_39315024 2.63 ENSDART00000012644
keratin 4
chr7_+_65532390 2.61 ENSDART00000156683
ENSDARG00000097673
chr10_+_6316944 2.52 ENSDART00000162428
tropomyosin 2 (beta)
chr23_-_9924987 2.51 ENSDART00000005015
protein kinase C binding protein 1, like
chr18_+_9413588 2.49 ENSDART00000061886
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr20_-_45819128 2.47 ENSDART00000124283
glycerophosphocholine phosphodiesterase 1
KN150207v1_-_1208 2.44 ENSDART00000171112
ENSDARG00000099354
chr7_+_40604000 2.40 ENSDART00000149395
sonic hedgehog a
chr3_-_45779817 2.39 ENSDART00000164361
glucagon receptor a
chr7_+_25641990 2.38 ENSDART00000129924
high mobility group box 3a
chr15_-_25582891 2.38

chr7_+_40603904 2.37 ENSDART00000149395
sonic hedgehog a
chr4_-_76620869 2.31

chr12_-_457997 2.30 ENSDART00000143232
dehydrogenase/reductase (SDR family) member 7Cb
chr10_-_44441481 2.29 ENSDART00000160231
strawberry notch homolog 1 (Drosophila)
chr22_+_13952935 2.29 ENSDART00000080313
ADP-ribosylation factor-like 4Ca
chr2_+_38057483 2.26 ENSDART00000159951
calsequestrin 1a
chr2_-_24357532 2.24 ENSDART00000137065
collagen, type XV, alpha 1b
chr23_+_36079164 2.23 ENSDART00000103131
homeo box C1a
chr12_+_28739504 2.21 ENSDART00000152991
nuclear factor, erythroid 2-like 1b
chr21_-_22510751 2.21 ENSDART00000169870
myosin VB
chr11_+_30482530 2.20 ENSDART00000103270
solute carrier family 22 (organic anion transporter), member 7a
chr17_+_381715 2.20 ENSDART00000162898
si:rp71-62i8.1
chr1_+_16681778 2.19

chr5_-_54773058 2.18 ENSDART00000145791
prune homolog 2 (Drosophila)
chr20_-_53162473 2.17 ENSDART00000164460
GATA binding protein 4
chr23_-_21520413 2.17 ENSDART00000044080
ENSDART00000112929
hairy-related 12
chr1_+_23093114 2.16

chr5_+_26840147 2.14 ENSDART00000064701
lysyl oxidase-like 2b
chr25_-_13518274 2.14 ENSDART00000165510
fatty acid 2-hydroxylase
chr2_+_52473102 2.13 ENSDART00000146418
Src homology 2 domain containing transforming protein D, a
chr15_-_23711689 2.13 ENSDART00000128644
creatine kinase, muscle b
chr2_-_24275851 2.12 ENSDART00000121885
transforming growth factor, beta receptor 1 a
chr25_-_33920256 2.11

chr22_+_10172134 2.09 ENSDART00000132641
pyruvate dehydrogenase (lipoamide) beta
chr13_+_22350043 2.09 ENSDART00000136863
LIM domain binding 3a
chr9_+_9524547 2.08 ENSDART00000061525
ENSDART00000125174
nuclear receptor subfamily 1, group I, member 2
chr6_-_49900124 2.07 ENSDART00000150204
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
chr7_+_19765237 2.07 ENSDART00000100808
B-cell CLL/lymphoma 6, member B
chr22_-_2870591 2.05 ENSDART00000063533
aquaporin 12
chr7_+_48532749 2.00 ENSDART00000145375
carnitine palmitoyltransferase 1Aa (liver)
chr16_-_39181608 2.00 ENSDART00000075517
growth differentiation factor 6a
chr6_-_40724581 1.99 ENSDART00000035101
kelch repeat and BTB (POZ) domain containing 12
chr13_-_219661 1.99 ENSDART00000133731
si:ch1073-291c23.2
chr8_-_23102555 1.98

chr9_-_22528568 1.98 ENSDART00000134805
crystallin, gamma M2d1
chr9_-_48152388 1.98

chr19_-_47994946 1.96 ENSDART00000114549
ENSDARG00000076126
chr13_+_30546398 1.95

chr17_+_135165 1.94 ENSDART00000166339
kelch domain containing 2
chr25_-_18855316 1.93 ENSDART00000155927
si:ch211-68a17.7
chr17_-_31041977 1.93 ENSDART00000104307
echinoderm microtubule associated protein like 1
chr9_-_53220424 1.90

chr5_-_21520111 1.90

chr19_-_5441932 1.88 ENSDART00000105034
type I cytokeratin, enveloping layer, like
chr25_+_35901081 1.88 ENSDART00000042271
ENSDART00000158027
iroquois homeobox 3b
chr1_-_40208544 1.87 ENSDART00000027463
H6 family homeobox 4
chr22_+_16511562 1.86

chr22_+_26543146 1.85

KN149795v1_-_24393 1.85

chr16_-_17439735 1.83 ENSDART00000144392
zyxin
chr11_-_6960107 1.80 ENSDART00000171255
cartilage oligomeric matrix protein
chr19_-_7069850 1.80 ENSDART00000145741
zinc finger protein 384 like
chr12_+_30119269 1.79 ENSDART00000102081
actin filament associated protein 1-like 2
chr23_-_35657313 1.79 ENSDART00000043429
junctophilin 2
chr21_+_5483017 1.78 ENSDART00000160885
starch binding domain 1
chr12_-_29190576 1.77 ENSDART00000153458
SH2 domain containing 4Bb
chr17_+_443558 1.75 ENSDART00000171386
zgc:194887
chr1_-_40208469 1.74 ENSDART00000027463
H6 family homeobox 4
chr2_+_393439 1.74 ENSDART00000122138
myosin light chain kinase family, member 4a
chr16_-_45943282 1.74 ENSDART00000133213
antifreeze protein type IV
chr20_-_29580624 1.74 ENSDART00000062370
actin, alpha, cardiac muscle 1a
chr13_-_39821399 1.74 ENSDART00000056996
secreted frizzled-related protein 5
chr21_-_3301751 1.73 ENSDART00000009740
SMAD family member 7
chr19_-_39048324 1.72 ENSDART00000086717
collagen, type XVI, alpha 1
chr22_-_26971466 1.72 ENSDART00000087202
ENSDARG00000061256
chr13_-_2259405 1.71 ENSDART00000166456
ELOVL fatty acid elongase 5
chr4_-_25847471 1.71 ENSDART00000142491
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr14_+_38375351 1.71 ENSDART00000175744
ENSDARG00000107351
chr23_+_26215871 1.71 ENSDART00000158878
protein tyrosine phosphatase, non-receptor type 22
chr2_-_14757989 1.71 ENSDART00000162816
ENSDARG00000099630
chr10_-_43711606 1.70 ENSDART00000170891
si:ch73-215f7.1
chr19_-_5416317 1.70 ENSDART00000010373
keratin, type 1, gene 19d
chr10_+_4717800 1.70 ENSDART00000161789
paralemmin 2
chr5_+_1223598 1.70 ENSDART00000159783
ENSDART00000026535
ENSDART00000168130
ENSDART00000147972
dynamin 1a
chr17_+_12254292 1.70 ENSDART00000160722
ketohexokinase
chr1_+_25157675 1.69 ENSDART00000136984
fatty acid binding protein 2, intestinal
chr4_-_935448 1.68 ENSDART00000171855
single-minded family bHLH transcription factor 1b
chr23_+_6298911 1.66 ENSDART00000139795
synaptotagmin IIa
chr24_-_16884946 1.66 ENSDART00000171988
prostaglandin D2 synthase b, tandem duplicate 2
chr17_+_134921 1.65 ENSDART00000166339
kelch domain containing 2
chr6_-_37481918 1.65 ENSDART00000130359
si:dkey-66a8.7
chr5_+_26832823 1.64 ENSDART00000124705
histone H1 like
chr8_+_48488009 1.64

chr1_-_18709814 1.62 ENSDART00000145224
RNA binding motif protein 47
chr13_-_37002066 1.61 ENSDART00000135510
spectrin repeat containing, nuclear envelope 2b
chr24_+_16249188 1.60 ENSDART00000164516
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr11_+_43559400 1.59

chr7_+_5372830 1.59 ENSDART00000135271
myeloid associated differentiation marker
chr11_-_7310284 1.59 ENSDART00000091664
adenomatosis polyposis coli 2
chr7_-_52434786 1.58 ENSDART00000131282
transcription factor 12
chr12_+_25006393 1.57 ENSDART00000050070
phosphatidylinositol glycan anchor biosynthesis, class F
chr9_-_21257082 1.56 ENSDART00000124533
T-box 15
chr7_+_25642061 1.56 ENSDART00000135728
high mobility group box 3a
chr9_-_1969197 1.55 ENSDART00000080608
homeobox D10a
chr23_+_4083697 1.54 ENSDART00000055099
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
chr3_-_32795866 1.53 ENSDART00000140117
amine oxidase, copper containing 2
chr21_+_15613081 1.53 ENSDART00000065772
D-dopachrome tautomerase
chr20_-_39200252 1.53 ENSDART00000037318
ENSDART00000143379
regulator of calcineurin 2
chr2_-_30005139 1.52 ENSDART00000146968
canopy1
chr17_-_17744885 1.52 ENSDART00000155261
SRA stem-loop interacting RNA binding protein
chr19_+_41274734 1.52 ENSDART00000126470
zgc:85777
chr10_+_34372205 1.51 ENSDART00000110121
StAR-related lipid transfer (START) domain containing 13a
chr19_+_3925188 1.51

chr9_-_34491458 1.50 ENSDART00000049805
immunoglobulin-like domain containing receptor 2
chr3_+_47735048 1.49 ENSDART00000083024
G protein-coupled receptor 146
chr19_+_4996328 1.49 ENSDART00000165082
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr14_-_46359248 1.49 ENSDART00000090844
zgc:153018
chr18_-_15963983 1.48 ENSDART00000127769
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr8_-_14146621 1.47 ENSDART00000063817
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11
chr11_-_33925792 1.47 ENSDART00000172978
ATPase type 13A3
chr23_+_18796386 1.46 ENSDART00000137438
myosin, heavy chain 7B, cardiac muscle, beta b
chr18_+_36650892 1.46 ENSDART00000098980
zinc finger protein 296
chr10_-_39210658 1.46 ENSDART00000150193
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr13_+_1377875 1.46

chr17_-_38831108 1.45 ENSDART00000124041
c17h14orf159 homolog (H. sapiens)
chr4_+_12033088 1.45 ENSDART00000044154
troponin T2c, cardiac
chr5_-_63031745 1.45

chr9_+_9524688 1.45 ENSDART00000061525
ENSDART00000125174
nuclear receptor subfamily 1, group I, member 2
chr1_-_46233556 1.45 ENSDART00000142560
pyridoxal (pyridoxine, vitamin B6) kinase b
chr18_-_48498261 1.44 ENSDART00000146346
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6
chr14_+_35906366 1.44 ENSDART00000105602
ELOVL fatty acid elongase 6
chr11_+_7148830 1.44 ENSDART00000035560
transmembrane protein 38A
chr3_-_26393945 1.44 ENSDART00000087118
xylosyltransferase I
chr7_+_25861386 1.44 ENSDART00000129834
N-acetyltransferase 16
chr9_-_711269 1.43 ENSDART00000144625
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3
chr16_+_25491981 1.43 ENSDART00000086333
jumonji, AT rich interactive domain 2a
chr25_-_30818836 1.43 ENSDART00000156828
proline rich 33
chr25_+_21732255 1.41 ENSDART00000027393
creatine kinase, mitochondrial 1
chr14_+_34174018 1.41 ENSDART00000024440
forkhead box I3b
chr5_+_26925238 1.41 ENSDART00000051491
secreted frizzled-related protein 1a
chr7_-_52848084 1.41 ENSDART00000172179
ENSDART00000167882
cadherin 1, type 1, E-cadherin (epithelial)
chr22_+_18218979 1.41

chr7_+_26980284 1.40 ENSDART00000173962
SRY (sex determining region Y)-box 6
chr8_+_49582361 1.40 ENSDART00000108613
RAS and EF-hand domain containing
chr22_+_30234718 1.40 ENSDART00000172496
adducin 3 (gamma) a
chr16_-_10404109 1.40

chr15_-_35563367 1.39

chr16_-_7321943 1.39 ENSDART00000149260
5'-nucleotidase, cytosolic IIIA
chr17_-_5426195 1.38 ENSDART00000035944
chloride intracellular channel 5a
chr12_+_42244935 1.38 ENSDART00000166484
si:ch211-221j21.3
chr2_-_20941256 1.37 ENSDART00000114199
si:ch211-267e7.3
chr21_-_2147085 1.36 ENSDART00000169262
zgc:163077
chr17_+_30431520 1.36 ENSDART00000153826
lipin 1
chr8_+_25714744 1.36 ENSDART00000156340
si:ch211-167b20.8
chr14_-_46359062 1.35 ENSDART00000090844
zgc:153018

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:1905178 regulation of cardiac muscle tissue regeneration(GO:1905178)
1.5 4.4 GO:0072578 neurotransmitter-gated ion channel clustering(GO:0072578)
1.0 3.1 GO:0046552 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.9 2.7 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.9 2.7 GO:0003241 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.8 3.2 GO:0051121 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.8 3.2 GO:0019543 propionate metabolic process(GO:0019541) propionate catabolic process(GO:0019543) glycerol biosynthetic process from pyruvate(GO:0046327) cellular response to dexamethasone stimulus(GO:0071549)
0.8 2.3 GO:0061130 branching involved in pancreas morphogenesis(GO:0061114) pancreatic bud formation(GO:0061130) pancreas field specification(GO:0061131)
0.8 4.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.8 2.3 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.7 2.1 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.6 1.8 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.6 4.1 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.6 1.7 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
0.5 5.9 GO:0033292 T-tubule organization(GO:0033292)
0.5 2.5 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.5 1.5 GO:0032675 interleukin-6 production(GO:0032635) regulation of interleukin-6 production(GO:0032675)
0.5 1.4 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.5 1.9 GO:0035777 pronephric distal tubule development(GO:0035777)
0.5 1.4 GO:0009957 epidermal cell fate specification(GO:0009957)
0.5 3.8 GO:0034633 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.5 3.6 GO:1901571 icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
0.4 3.5 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.4 1.3 GO:0086010 mechanosensory behavior(GO:0007638) membrane depolarization during action potential(GO:0086010)
0.4 3.8 GO:0050936 xanthophore differentiation(GO:0050936)
0.4 1.2 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.4 1.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.4 1.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.4 0.8 GO:0048664 neuron fate determination(GO:0048664)
0.4 2.8 GO:0090177 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.4 1.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.4 1.5 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.4 2.2 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.4 2.2 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.4 1.1 GO:1902869 negative regulation of photoreceptor cell differentiation(GO:0046533) regulation of amacrine cell differentiation(GO:1902869) positive regulation of amacrine cell differentiation(GO:1902871)
0.4 1.4 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332) positive regulation of cartilage development(GO:0061036)
0.3 1.7 GO:0003197 endocardial cushion development(GO:0003197)
0.3 1.7 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.3 1.0 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.3 0.9 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.3 2.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.3 2.2 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.3 2.7 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.3 1.4 GO:0003379 establishment of cell polarity involved in gastrulation cell migration(GO:0003379)
0.3 1.1 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.3 0.5 GO:1903010 regulation of bone development(GO:1903010)
0.3 1.6 GO:2000742 regulation of anterior head development(GO:2000742)
0.3 1.1 GO:1901490 regulation of lymphangiogenesis(GO:1901490) positive regulation of lymphangiogenesis(GO:1901492)
0.3 1.1 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.3 1.0 GO:0003085 negative regulation of systemic arterial blood pressure(GO:0003085)
0.2 0.7 GO:0030431 sleep(GO:0030431)
0.2 2.1 GO:0016203 muscle attachment(GO:0016203)
0.2 0.7 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.2 1.3 GO:0009110 vitamin biosynthetic process(GO:0009110)
0.2 2.9 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.2 1.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 1.2 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.2 0.8 GO:0010996 response to auditory stimulus(GO:0010996)
0.2 1.0 GO:1902221 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.2 1.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 3.7 GO:0030199 collagen fibril organization(GO:0030199)
0.2 1.1 GO:0006833 water transport(GO:0006833)
0.2 3.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 0.9 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.2 2.9 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.2 0.5 GO:0030279 negative regulation of ossification(GO:0030279)
0.2 0.5 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2 0.7 GO:0048025 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025) negative regulation of cell aging(GO:0090344) regulation of cellular senescence(GO:2000772)
0.2 0.8 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.2 0.7 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.2 2.9 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.2 0.5 GO:0052805 imidazole-containing compound metabolic process(GO:0052803) imidazole-containing compound catabolic process(GO:0052805)
0.2 0.9 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.2 10.2 GO:0007601 visual perception(GO:0007601)
0.2 0.5 GO:2000583 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
0.1 0.4 GO:0030852 regulation of collagen metabolic process(GO:0010712) regulation of granulocyte differentiation(GO:0030852) plasminogen activation(GO:0031639) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246) regulation of neutrophil differentiation(GO:0045658)
0.1 3.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 2.2 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.8 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 1.4 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.1 1.8 GO:0097320 membrane tubulation(GO:0097320)
0.1 1.2 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 1.6 GO:0009746 response to carbohydrate(GO:0009743) response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.1 0.8 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 2.1 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 0.8 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.1 0.9 GO:0061621 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.4 GO:0002504 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.1 0.6 GO:0071632 optomotor response(GO:0071632)
0.1 0.4 GO:0061032 visceral serous pericardium development(GO:0061032) glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.1 0.4 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 1.2 GO:0006956 complement activation(GO:0006956)
0.1 0.6 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 1.0 GO:0032264 IMP salvage(GO:0032264)
0.1 2.0 GO:0032963 collagen metabolic process(GO:0032963) multicellular organismal macromolecule metabolic process(GO:0044259)
0.1 1.2 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 0.8 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1 0.3 GO:0035776 pronephric proximal tubule development(GO:0035776)
0.1 1.3 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.1 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 0.3 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.4 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.1 9.4 GO:0006936 muscle contraction(GO:0006936)
0.1 1.8 GO:0007632 visual behavior(GO:0007632)
0.1 0.9 GO:0050919 negative chemotaxis(GO:0050919)
0.1 1.4 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 1.5 GO:0060030 dorsal convergence(GO:0060030)
0.1 1.1 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.5 GO:0007183 SMAD protein complex assembly(GO:0007183) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 3.1 GO:0034599 cellular response to oxidative stress(GO:0034599)
0.1 1.5 GO:0002250 adaptive immune response(GO:0002250)
0.1 6.5 GO:0071560 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.1 2.1 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.3 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.1 0.7 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 1.2 GO:0001952 regulation of cell-matrix adhesion(GO:0001952)
0.1 0.6 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.5 GO:1902946 protein localization to endosome(GO:0036010) protein localization to early endosome(GO:1902946)
0.1 0.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 1.2 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 1.3 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.1 2.7 GO:0009636 response to toxic substance(GO:0009636)
0.1 0.8 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 8.6 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.1 0.3 GO:0030224 monocyte differentiation(GO:0030224)
0.1 1.0 GO:1900046 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.1 3.1 GO:0007416 synapse assembly(GO:0007416)
0.1 0.4 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.5 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.1 0.3 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.1 1.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 1.2 GO:1900076 regulation of insulin receptor signaling pathway(GO:0046626) regulation of cellular response to insulin stimulus(GO:1900076)
0.1 0.3 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.1 0.2 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.1 0.6 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823) regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.1 1.1 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 0.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 2.0 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 0.7 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 0.6 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.1 0.7 GO:0018149 peptide cross-linking(GO:0018149)
0.1 1.4 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 1.3 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.1 1.3 GO:0050773 regulation of dendrite development(GO:0050773)
0.1 1.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 1.0 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 3.2 GO:0006979 response to oxidative stress(GO:0006979)
0.1 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.1 0.5 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 0.9 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 1.5 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 0.2 GO:0090398 cellular senescence(GO:0090398)
0.1 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.3 GO:1900028 negative regulation of Rac protein signal transduction(GO:0035021) wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.1 0.3 GO:1903286 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 1.1 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 0.4 GO:0019226 transmission of nerve impulse(GO:0019226)
0.1 1.9 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 2.4 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.3 GO:0034969 histone arginine methylation(GO:0034969)
0.1 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.7 GO:0031033 myosin filament organization(GO:0031033)
0.1 2.9 GO:0045010 actin nucleation(GO:0045010)
0.1 2.7 GO:0051781 positive regulation of cell division(GO:0051781)
0.1 0.8 GO:0035675 neuromast hair cell development(GO:0035675)
0.1 0.8 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.3 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.1 0.8 GO:0014823 response to activity(GO:0014823)
0.1 1.1 GO:1903307 positive regulation of calcium ion-dependent exocytosis(GO:0045956) positive regulation of regulated secretory pathway(GO:1903307)
0.1 0.3 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 0.4 GO:0042744 hydrogen peroxide metabolic process(GO:0042743) hydrogen peroxide catabolic process(GO:0042744)
0.1 0.8 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 0.7 GO:0001966 thigmotaxis(GO:0001966)
0.1 2.0 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.7 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 1.1 GO:0046460 triglyceride biosynthetic process(GO:0019432) neutral lipid biosynthetic process(GO:0046460) acylglycerol biosynthetic process(GO:0046463)
0.1 1.1 GO:0046847 filopodium assembly(GO:0046847)
0.0 1.3 GO:0043049 otic placode formation(GO:0043049)
0.0 1.5 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.9 GO:0061386 closure of optic fissure(GO:0061386)
0.0 7.5 GO:0007517 muscle organ development(GO:0007517)
0.0 0.7 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 2.2 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.2 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.7 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 1.9 GO:0006821 chloride transport(GO:0006821)
0.0 0.2 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 1.0 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 1.6 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.2 GO:0051029 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
0.0 1.4 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.3 GO:0001843 neural tube closure(GO:0001843)
0.0 2.2 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.0 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 1.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.7 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 0.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.6 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 1.8 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 1.0 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 1.8 GO:0001503 ossification(GO:0001503)
0.0 1.1 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.5 GO:0016525 negative regulation of angiogenesis(GO:0016525) negative regulation of blood vessel morphogenesis(GO:2000181)
0.0 0.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.3 GO:0060840 artery development(GO:0060840)
0.0 1.3 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 1.3 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 3.3 GO:0031016 pancreas development(GO:0031016)
0.0 0.3 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 1.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.6 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228) synaptic transmission, GABAergic(GO:0051932)
0.0 0.1 GO:1901998 toxin transport(GO:1901998)
0.0 0.4 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.0 0.1 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.0 0.6 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.9 GO:0021782 glial cell development(GO:0021782)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.3 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.7 GO:0001708 cell fate specification(GO:0001708)
0.0 0.9 GO:0001756 somitogenesis(GO:0001756)
0.0 0.8 GO:0033339 pectoral fin development(GO:0033339)
0.0 0.1 GO:0015822 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.0 0.2 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.9 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.2 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.7 GO:0022900 electron transport chain(GO:0022900)
0.0 0.1 GO:0071265 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 1.9 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 0.2 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.3 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.4 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.2 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.1 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 1.5 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.8 GO:0031101 fin regeneration(GO:0031101)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.0 GO:0070476 peptidyl-glutamine methylation(GO:0018364) rRNA (guanine-N7)-methylation(GO:0070476)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.8 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.8 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 0.1 GO:0010878 cholesterol storage(GO:0010878) regulation of cholesterol storage(GO:0010885)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 2.1 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.1 GO:0009435 NAD biosynthetic process(GO:0009435)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.9 2.6 GO:0030314 junctional membrane complex(GO:0030314)
0.5 5.5 GO:0031430 M band(GO:0031430)
0.5 2.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.4 3.9 GO:0016011 dystroglycan complex(GO:0016011)
0.4 2.1 GO:0048179 activin receptor complex(GO:0048179)
0.3 1.7 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.3 2.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.3 3.4 GO:0030667 secretory granule membrane(GO:0030667)
0.3 4.6 GO:0031594 neuromuscular junction(GO:0031594)
0.3 10.5 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.3 2.9 GO:0030056 hemidesmosome(GO:0030056)
0.2 2.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 2.6 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.2 9.3 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 1.3 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.2 0.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 10.8 GO:0005581 collagen trimer(GO:0005581)
0.2 6.2 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.2 0.7 GO:0070062 extracellular exosome(GO:0070062)
0.2 1.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 4.1 GO:0044420 basement membrane(GO:0005604) extracellular matrix component(GO:0044420)
0.2 3.3 GO:0045095 keratin filament(GO:0045095)
0.1 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.7 GO:0005869 dynactin complex(GO:0005869)
0.1 6.9 GO:0005882 intermediate filament(GO:0005882)
0.1 0.9 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 5.8 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.8 GO:0043195 terminal bouton(GO:0043195)
0.1 3.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 2.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 5.0 GO:0016459 myosin complex(GO:0016459)
0.1 2.7 GO:0034707 chloride channel complex(GO:0034707)
0.1 1.7 GO:0031941 filamentous actin(GO:0031941)
0.1 0.3 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 1.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.2 GO:0043034 costamere(GO:0043034)
0.1 0.3 GO:0046930 pore complex(GO:0046930)
0.1 1.5 GO:0005902 microvillus(GO:0005902)
0.1 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.2 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.7 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.4 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.1 0.8 GO:0043209 myelin sheath(GO:0043209)
0.1 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.5 GO:0005899 insulin receptor complex(GO:0005899)
0.1 1.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 36.1 GO:0005615 extracellular space(GO:0005615)
0.1 0.7 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.2 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.1 1.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 2.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.2 GO:0070822 Sin3-type complex(GO:0070822)
0.1 0.2 GO:0032420 stereocilium(GO:0032420)
0.1 2.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 16.1 GO:0005576 extracellular region(GO:0005576)
0.1 0.2 GO:0071020 post-spliceosomal complex(GO:0071020)
0.1 3.3 GO:0043025 neuronal cell body(GO:0043025)
0.1 2.8 GO:0005884 actin filament(GO:0005884)
0.1 0.4 GO:0031838 hemoglobin complex(GO:0005833) haptoglobin-hemoglobin complex(GO:0031838)
0.0 1.4 GO:0008305 integrin complex(GO:0008305)
0.0 2.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.4 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 1.0 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 1.0 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.6 GO:0045177 apical plasma membrane(GO:0016324) apical part of cell(GO:0045177)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.6 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 2.4 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 1.7 GO:0030424 axon(GO:0030424)
0.0 1.2 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.7 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 2.4 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.5 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.7 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.2 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.8 4.2 GO:2001070 starch binding(GO:2001070)
0.8 3.2 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.8 3.8 GO:0034632 retinol transporter activity(GO:0034632)
0.7 4.3 GO:0015250 water channel activity(GO:0015250)
0.7 2.7 GO:0004738 pyruvate dehydrogenase activity(GO:0004738)
0.6 1.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.5 2.2 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.5 2.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.5 2.0 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.5 1.4 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.5 1.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.5 4.8 GO:0005113 patched binding(GO:0005113)
0.5 0.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.5 3.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.4 1.8 GO:0042169 SH2 domain binding(GO:0042169)
0.4 3.5 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.4 6.0 GO:0005523 tropomyosin binding(GO:0005523)
0.4 0.8 GO:0005119 smoothened binding(GO:0005119)
0.4 1.2 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.4 1.1 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.4 2.2 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.4 2.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.3 1.0 GO:0008131 primary amine oxidase activity(GO:0008131)
0.3 2.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.3 8.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 1.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 4.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324) fatty acid transporter activity(GO:0015245)
0.3 1.4 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.3 1.9 GO:0003993 acid phosphatase activity(GO:0003993)
0.3 3.0 GO:0004623 phospholipase A2 activity(GO:0004623)
0.3 2.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.3 0.8 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.3 2.9 GO:0030506 ankyrin binding(GO:0030506)
0.3 0.8 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.2 1.0 GO:0033971 hydroxyisourate hydrolase activity(GO:0033971)
0.2 3.7 GO:0005518 collagen binding(GO:0005518)
0.2 3.9 GO:0043236 laminin binding(GO:0043236)
0.2 1.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.2 3.1 GO:0038191 neuropilin binding(GO:0038191)
0.2 0.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.2 4.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.2 1.0 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.2 1.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 0.6 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.2 2.4 GO:0017046 peptide hormone binding(GO:0017046)
0.2 0.6 GO:0097016 L27 domain binding(GO:0097016)
0.2 1.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 3.2 GO:0008301 DNA binding, bending(GO:0008301)
0.2 1.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 0.7 GO:0019201 nucleotide kinase activity(GO:0019201)
0.2 1.2 GO:0043495 protein anchor(GO:0043495)
0.2 0.7 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.2 0.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 1.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 0.8 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 0.8 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.2 2.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 1.7 GO:0005504 fatty acid binding(GO:0005504)
0.2 2.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 0.5 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 1.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 1.3 GO:0016531 copper chaperone activity(GO:0016531)
0.1 8.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.2 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.7 GO:0051429 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 3.3 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.8 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 2.5 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.8 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 1.2 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.9 GO:0070095 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.1 1.7 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.0 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.6 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.4 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.1 5.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.5 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 1.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.3 GO:0015288 porin activity(GO:0015288)
0.1 0.4 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 1.9 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 0.9 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.7 GO:0016722 oxidoreductase activity, oxidizing metal ions(GO:0016722)
0.1 0.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 1.4 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.9 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.1 0.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.3 GO:0070699 adrenergic receptor binding(GO:0031690) beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
0.1 0.4 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 1.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.5 GO:0036122 BMP binding(GO:0036122)
0.1 0.5 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 1.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.1 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.3 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 1.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.1 2.8 GO:0005267 potassium channel activity(GO:0005267)
0.1 2.8 GO:0005109 frizzled binding(GO:0005109)
0.1 0.4 GO:0042287 MHC protein binding(GO:0042287)
0.1 1.4 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.2 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.2 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.1 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.5 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.1 1.3 GO:0015248 sterol transporter activity(GO:0015248)
0.1 2.8 GO:0008201 heparin binding(GO:0008201)
0.1 0.3 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.1 1.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 2.5 GO:0008013 beta-catenin binding(GO:0008013)
0.1 0.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.4 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.3 GO:0017081 chloride channel regulator activity(GO:0017081) chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 1.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 14.0 GO:0051015 actin filament binding(GO:0051015)
0.1 0.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.4 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.4 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.1 1.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.5 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 1.6 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 2.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.8 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 2.6 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.9 GO:0005254 chloride channel activity(GO:0005254)
0.0 1.2 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 6.7 GO:0003779 actin binding(GO:0003779)
0.0 2.3 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0035620 ceramide transporter activity(GO:0035620) sphingolipid transporter activity(GO:0046624) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.0 1.9 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.7 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 6.8 GO:0008017 microtubule binding(GO:0008017)
0.0 0.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.1 GO:0030151 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725) molybdenum ion binding(GO:0030151)
0.0 0.2 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 9.0 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.6 GO:0051427 hormone receptor binding(GO:0051427)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 1.6 GO:0015293 symporter activity(GO:0015293)
0.0 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 2.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.8 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.0 22.8 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 4.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.6 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 1.7 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 4.7 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.7 GO:0019838 growth factor binding(GO:0019838)
0.0 0.9 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.7 GO:0005125 cytokine activity(GO:0005125)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.4 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.7 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.9 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.4 2.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 3.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.2 3.7 NABA COLLAGENS Genes encoding collagen proteins
0.1 0.8 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 2.3 PID ALK1 PATHWAY ALK1 signaling events
0.1 0.9 PID IL5 PATHWAY IL5-mediated signaling events
0.1 2.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 4.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 4.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 6.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 1.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.0 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 3.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.3 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.5 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.3 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.2 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 1.0 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.4 2.7 REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.3 1.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3 2.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 2.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.2 2.9 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.2 1.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 2.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 1.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 1.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 3.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 3.8 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.2 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 0.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 2.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 9.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 3.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 0.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 1.1 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 0.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 3.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.8 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.1 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.1 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.7 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 1.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport